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1 23 Cognitive Therapy and Research ISSN 0147-5916 Cogn Ther Res DOI 10.1007/s10608-011-9381- z A Latent Profile Analysis of Implicit and Explicit Cognitions Associated with Depression Wendy J. Phillips, Donald W. Hine & Navjot Bhullar

A Latent Profile Analysis of Implicit and Explicit Cognitions Associated with Depression

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1 23

Cognitive Therapy andResearch ISSN 0147-5916 Cogn Ther ResDOI 10.1007/s10608-011-9381-z

A Latent Profile Analysis of Implicitand Explicit Cognitions Associated withDepression

Wendy J. Phillips, Donald W. Hine &Navjot Bhullar

1 23

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ORIGINAL ARTICLE

A Latent Profile Analysis of Implicit and Explicit CognitionsAssociated with Depression

Wendy J. Phillips • Donald W. Hine •

Navjot Bhullar

� Springer Science+Business Media, LLC 2011

Abstract Dual-process cognitive profiles associated with

depression were identified in an undergraduate sample

(N = 306) and dysphoric sub-sample (n = 57). Two

Latent Profile Analyses (LPAs) were conducted on four

implicit and four explicit cognitions associated with

depression (self-esteem, negative memory, positive mem-

ory and dysfunctional beliefs). The first LPA, performed on

the total sample, produced a three-profile solution reflect-

ing quantitative shifts from generally negative, through

intermediate, to generally positive biases on both implicit

and explicit indicators. Patterns of biases across the profiles

were associated with incremental decreases in current

depressive symptoms, and logistic regression revealed that

profile membership significantly predicted depression sta-

tus 3 months later. Sequential logistic regression indicated

that implicit self-esteem was the strongest predictor of

subsequent dysphoria. The second LPA, focusing on a

subgroup of dysphoric participants, identified two qualita-

tively distinct profiles that may represent cognitive sub-

types of depression: (1) a schematic profile with multiple

negative biases and (2) a profile dominated by implicit

negative memory. These results are consistent with the

dual-process premise that implicit and explicit cognitive

processes are involved in depression and suggest that

treatment efficacy may be improved by incorporating

strategies that address implicit cognitive biases.

Keywords Depression � Cognitive bias � Dual-process �Implicit � Explicit

Individual responses to stressful or sad events differ

markedly. While some people experience temporary psy-

chological discomfort, others become overwhelmed by

despair. Influential cognitive theories of depression assume

that depression-vulnerable individuals possess negative

self-referential cognitions that precipitate negative

responses to daily stressors, which in turn lead to depres-

sion (Abramson et al. 1989; Beck 1987; Ingram 1984;

Teasdale 1988). Accordingly, an array of negative self-

cognitions have predicted subsequent depressive symp-

tomatology (Abramson et al. 2002; Joormann 2009; Wisco

2009)—including low or unstable self-esteem (e.g., Franck

and De Raedt 2007; Orth et al. 2009), heightened memory

for negative self-referential or emotional stimuli (e.g.,

Bellew and Hill 1991), decreased memory for positive

stimuli (e.g., Johnson et al. 2007), dysfunctional attitudes

(e.g., Reilly-Harrington et al. 1999), and self-deprecating

interpretations of ambiguous information (e.g., Rude et al.

2002). In support of cognitive vulnerability hypotheses,

several self-cognitions have also been found to interact

with stressful events to predict future depression; including

self-esteem, memory bias, and dysfunctional attitudes

(e.g., Bellew and Hill 1991; Haeffel et al. 2007; Reilly-

Harrington et al. 1999).

Recently, theorists have suggested that cognitive vul-

nerability to depression may result from an interaction

between two distinct information processing systems

(Beevers 2005; Carver et al. 2008; Haeffel et al. 2007).

This dual-process perspective recognizes the existence of

an implicit system that is automatic, effortless, affect-

oriented and guided by associative memory, and an explicit

system that is deliberate, motivated, effortful and directed

by rule-based learning (for review, see Evans 2008).

Neurophysiological research suggests that the proposed

cognitive systems map onto two distinct neurological

W. J. Phillips (&) � D. W. Hine � N. Bhullar

School of Behavioural, Cognitive and Social Sciences,

University of New England, Armidale, NSW 2351, Australia

e-mail: [email protected]; [email protected]

123

Cogn Ther Res

DOI 10.1007/s10608-011-9381-z

Author's personal copy

systems (e.g., Lieberman et al. 2004). Dual-process

accounts also tacitly differentiate between explicit output

(i.e., what one thinks) and explicit processes (i.e., how one

thinks). Explicit processing refers to how we interpret a

stimulus (e.g., our cognitive style; Alloy et al. 2000),

whereas explicit output refers to our final conscious inter-

pretation of the stimulus (e.g., our attitude). This distinc-

tion has been empirically supported in relation to

depressive cognitive constructs (Ciesla and Roberts 2007).

As system outputs, implicit and explicit cognitions are

presumed to possess characteristics of their originating

system, which require different modes of assessment.

Measures of explicit cognitions are based on participants’

deliberate consideration (e.g., self-reports) whereas impli-

cit cognitions may be assessed under automatic conditions

(e.g., memory associations). According to Moors et al.

(2010), measures may be automatic in several ways,

including unconscious, uncontrolled, goal-independent,

fast and efficient, and automaticity features may not nec-

essarily co-exist within a particular measure. Traditionally,

researchers have tended to assess depression-related cog-

nitions in the context of predictions made by depression

theories (e.g., Cognitive Theory; Beck 1987). However,

extant research can also be classified according to its

implicit or explicit status. All hypothesised depression-

related cognitions that have been assessed by explicit

measures may be considered explicit depressive cognitions

and all those assessed using implicit methods may be

considered implicit depressive cognitions.

Most dual-process models propose that implicit cogni-

tions reflect initial responses to a stimulus and that explicit

cognitions follow as the result of conscious reflection (see

Evans 2008). Beevers (2005) proposed that depression

occurs when negatively biased implicit processing remains

uncorrected by explicit processing. An initial response to a

negative stimulus is believed to reflect the activation of

negative implicit self-schemas. Effortful explicit process-

ing may perform a corrective function by reinterpreting

stressful stimuli, overriding implicit negative responses and

relieving negative affect. However, if corrective processing

is unsuccessful, negatively biased implicit output will be

reflected in negative explicit cognitions; resulting in

increased dysphoria, depleted cognitive resources and a

downward spiral into depression. Carver et al. (2008)

offered a similar perspective in their review of behavioural,

brain function, and serotonin studies relating to two system

models and depressive vulnerability.

Considerable evidence supports this conceptualisation

(see Beck 2008; Beevers 2005; Carver et al. 2008). For

example, experimental manipulations to deplete cognitive

resources have revealed automatic negative biases amongst

depression-vulnerable individuals that were not otherwise

evident (e.g., Wenzlaff and Bates 1998). Additionally,

neurophysiological evidence suggests that depression may

occur when regulatory functions of top-down (explicit)

processing are undermined and maladaptive bottom-up

(implicit) processing is exposed (see Beck 2008; Carver

et al. 2008; Thase 2009). Haeffel et al. (2007) proposed a

similar dual-process model of depression, but placed

greater emphasis on the influence of explicit processing as

the creator of the final interpretation of an event.

Researchers are currently investigating cognitive

mechanisms that may be involved in an interaction

between processing systems in depression (e.g., Philippot

and Brutoux 2008). However, little research has addressed

the coexistence of multiple implicit and explicit cognitive

biases within individuals, and how they co-exist to predict

current and future depressive symptoms.

One outstanding issue involves determining whether the

structure of dual-process cognitions associated with

depression is best conceptualised as dimensional or cate-

gorical. Specifically, it is not known whether implicit and

explicit cognitive biases coincide to reflect quantitative

differences along one or more continuous dimensions, or

whether these biases co-exist to create qualitatively distinct

subtypes of vulnerable and non-vulnerable individuals.

Only one study has examined the dimensionality of cog-

nitive vulnerability to depression in an unspecified sample.

Gibb and colleagues’ (2004) used taxometric procedures

developed by Meehl and colleagues (see Waller and Meehl

1998) to determine whether the latent structure of dys-

functional attitudes and cognitive styles was dimensional

or categorical. The analysis indicated that explicit cognitive

vulnerability to depression was dimensional amongst

undergraduates. That is, all participants possessed both

explicit depressive cognitions to some degree, and higher

levels of vulnerability were associated with greater

depressive symptomatology. Relatedly, depressive symp-

toms appear to be dimensionally distributed in unspecified

samples (e.g., Ruscio and Ruscio 2002)—although taxons

(i.e., distinct groups of symptoms) have been observed in

depressed samples (e.g., Ruscio et al. 2009).

Such dimensionality of explicit self-referential cogni-

tions and symptoms is consistent with most dual-process

accounts of depression, insofar as they posit that negative

explicit cognitions may emerge as a consequence of un-

curtailed negative implicit output (Beevers 2005; Carver

et al. 2008) and immediately precede and coincide with

depressive symptomatology (Beevers 2005; Carver et al.

2008; Haeffel et al. 2007). To date, no taxometric studies

of implicit cognitive vulnerabilities to depression have

been conducted. However, consistent with a dimensional

structure, significant relationships between negative

implicit cognitive biases and depression have been

observed in various sampled populations (Phillips et al.

2010) and implicit interpretations of ambiguous stories

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have been found to vary systematically from negative to

positive across depressed, dysphoric and non-depressed

groups (Halberstadt et al. 2008). Therefore, to the extent

that explicit cognitive vulnerability appears to be dimen-

sional, underlying implicit cognitive vulnerabilities may

take a similarly quantitative form that foretells explicit

vulnerabilities and current depressive symptoms.

Alternatively, it is possible that dual-process cognitive

profiles in depression may adopt a qualitative structure.

Logically, four general co-occurrences of depressive cog-

nitions may exist: positive implicit/positive explicit; posi-

tive implicit/negative explicit; negative implicit/positive

explicit; and negative implicit/negative explicit—where

positive and negative refer to levels above and below

average, respectively.

The existence of profiles with compatible implicit and

explicit cognitions is supported by the evidence cited

above. Yet simultaneous possession of conflicting levels of

implicit and explicit depression-related cognitions has also

been observed and associated with a range of adverse

mental health outcomes (see Brinol et al. 2006). For

example, possession of high explicit and low implicit self-

esteem has been associated with poor emotional well-being

(Zelenski and Larsen 2003; cited in Brinol et al. 2006), and

possession of high implicit and low explicit self-esteem has

been associated with depressive cognitive styles and ner-

vousness (Schroder-Abe et al. 2007). Additionally, some

studies have observed relationships between high implicit

self-esteem and depression (e.g., Franck et al. 2007)

despite an overall association with low implicit self-esteem

in the literature (Phillips et al. 2010).

Both possible conflicting cognitive profiles are also

consistent with proposed dual-process mechanisms in

depression. Beevers (2005) and Haeffel et al. (2007) pro-

posed that negative implicit self-cognitions confer cogni-

tive vulnerability to depression. However, individuals with

latent negative implicit biases may escape dysphoria if

explicit processing can override implicit output and create

co-occurring positive explicit cognitions. Accordingly,

negative stressors have precipitated greater activation of a

variety of negative explicit depressive cognitions in for-

merly-dysphoric than in never-dysphoric groups (see Scher

et al. 2005). In contrast, positive implicit and negative

explicit cognitions may co-occur when maladaptive

explicit processing has overridden positive implicit output.

Haeffel et al. (2007) made the additional prediction that the

latter profile may also render an individual vulnerable to

future depression.

Whether dual-process depressive cognitive profiles are

dimensional or categorical, most cognitive theories of

depression predict that individuals who possess negatively

biased self-referential cognitions are particularly likely to

become depressed in the future (Abramson et al. 1989;

Beck 1987; Beevers 2005; Ingram 1984). However, dual-

process theorists differ in their predictions regarding which

type of processing confers the greater vulnerability to

depression. Beevers’ (2005) and Carver et al.’s (2008)

position suggests that individuals whose cognitive profiles

comprise negative implicit self-cognitions are most likely

to experience long-term depressive reactions, whereas

Haeffel et al. (2007) model suggests that cognitive profiles

containing negative explicit cognitions carry greater risk. If

dual-process depressive cognitive profiles are qualitative in

nature, then assessing which profiles confer risk for future

dysphoria has the capacity to shed light on the relative risk

conferred by implicit and explicit cognitions and their

co-occurrence.

A separate but related field of enquiry has investigated

the existence of subtypes of depression. Although taxo-

metric and factor-analytic studies of clinically depressed

samples have tended to identify a melancholic subtype of

depressive symptomatology (e.g., Haslam and Beck 1994),

few have supported the independence of specific clusters of

cognitions predicted by putative depression subtypes, such

as hopelessness (HT; Abramson et al. 1989), autonomous

and sociotropic (CT; Beck 1987), and self-critical (Blatt

and Homann 1992) depression (for reviews, see Adams

et al. 2007; Haslam 2007). For example, a factor analysis

conducted by Reno and Halaris (1989) did not differentiate

explicit cognitions stemming from HT and CT in a sample

of depressed inpatients, where depressive explanatory and

attributional styles (HT) and dysfunctional attitudes (CT)

loaded onto the same factor. Although it should be noted

that factor analytical studies have discriminated between

cognitions associated with putative subtypes (e.g., HT and

CT) in non-clinical, undergraduate, samples (e.g., Hankin

et al. 2007). One shortcoming of extant taxonic research is

the failure to investigate implicit depressive cognitions as

potential discriminators of depressive subtypes. The pos-

sibility that subtypes of depression may reflect differences

in implicit, but not explicit, negative cognitive biases (or

vice versa) has not been assessed.

The Current Study

The current study aimed to identify dual-process cognitive

profiles associated with depression by conducting a Latent

Profile Analysis (LPA) of four implicit and four explicit

cognitions associated with depression (i.e., implicit and

explicit self-esteem, positive and negative memory biases,

and dysfunctional self-beliefs) and to assess their ability to

predict subsequent depression. Our selection of cognitive

indicators was guided by dual-process theory. We selected

four explicit depression-related cognitions that have been

empirically identified as cognitive vulnerabilities for

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depression1 and paired them with implicit measures that

purport to assess conceptually similar constructs.

LPA is a model-based procedure that groups participants

according to shared responses across multiple measures.

Grouping participants according to their cognitive charac-

teristics may facilitate insight into the relationships

between depression-related implicit and explicit cognitions

and how they co-exist to manifest in depression. In turn,

this may increase our understanding of cognitive vulnera-

bility to depression. Given that interventions for depression

typically address cognitive biases (e.g., Beck et al. 1979),

the results of this study may also inform the refinement of

treatment strategies.

Our primary aim was to determine whether dual-process

cognitive profiles associated with depression would exhibit

a quantitative or qualitative structure in an undergraduate

sample. Guided by dual-process theory and empirical evi-

dence, we hypothesized two alternative outcomes: (1a) At

least two quantitative profiles would emerge—one com-

prising dysphoric individuals with negative biases on all

implicit and explicit cognitions and another comprising

non-dysphoric individuals with positive biases on all cog-

nitions; and (1b) At least four qualitative profiles would

emerge, including profiles comprising: negative implicit

and explicit biases, negative implicit and positive explicit

biases; positive implicit and explicit biases; and positive

implicit and negative explicit biases.

Second, we aimed to investigate whether the profile

solution would predict participants’ depressive status

3 months later. On the basis of Beevers’ (2005) dual-

process theory and extant evidence, we hypothesized that:

(2) Emergent profiles featuring negatively biased implicit

and explicit cognitions or negative implicit and positive

explicit cognitions would predict subsequent depressive

status.

Third, we hoped to identify the relative contributions of

the eight cognitive indicators to future depression status.

We made no predictions regarding specific negatively

biased cognitions, but formed the general hypothesis that:

(3) Implicit biases would represent stronger predictors of

subsequent depressive status than explicit biases.

Fourth, we aimed to analyse a sub-sample of dysphoric

participants to identify dual-process cognitive profiles that

may represent subtypes of depression, and to compare

them with the cognitive profiles of never-depressed

participants.

Method

Participants

Three hundred and six first year undergraduates (57 Males

and 249 Females) at the University of New England par-

ticipated at Time 1 to receive course credits. Ages ranged

from 18 to 66 years (M = 29.91, SD = 10.72;

Median = 27.00).

Cognitive Bias Measures

Implicit Self-Esteem

The Name Letter Preference Task (NLPT; Nuttin 1985)

assesses preferences for one’s own name initials, which

have been shown to reflect self-evaluations that are acti-

vated automatically and without conscious self-reflection

(Koole et al. 2001). All letters of the alphabet were pre-

sented individually, in random order, for (up to) 30 s each.

Participants rated each letter from 1) not at all attractive to

9) very attractive. A practice session involving three

numbers preceded the task. Variable scores were calculated

from participants’ initials using the Z-transformed double-

correction algorithm (LeBel and Gawronski 2009). The

NLPT has previously demonstrated convergent and con-

struct validity (Koole et al. 2001) and test–retest reliability

(Bosson, Swann, and Pennebaker 2000). We assessed

reliability of the NLPT in the current study by calculating

Cronbach’s alpha from all letter scores after replacing each

participant’s own initial scores with the sample mean for

those letters (a = .84).

Explicit Self-Esteem

The Rosenberg Self-Esteem Scale (RSE; Rosenberg 1965)

includes 10 statements of self-worth (e.g., ‘‘On the whole, I

am satisfied with myself’’). Participants indicated agree-

ment with each statement from 1) totally agree to 4) totally

disagree. Scale scores were calculated by summing across

items (a = .91).

Implicit Dysfunctional Beliefs

The Scrambled Sentences Test (SST; Wenzlaff 1993)

measured participants’ tendency to interpret ambiguous

self-referential information (e.g., ‘‘winner born I am loser

a’’) in a positive way (‘‘I am a born winner’’) or a negative

way (‘‘I am a born loser’’). Insofar as interpretations

express underlying beliefs, we are referring to interpreta-

tions as implicit dysfunctional beliefs for ease of compar-

ison with explicit dysfunctional beliefs. Participants

unscrambled 20 sentences in 4 min to form the first

1 We did not include cognitive styles because we believe their

measure assesses explicit processes as well as output and no

conceptually equivalent implicit measure exists.

Cogn Ther Res

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grammatically correct sentences that came to mind. Par-

ticipants simultaneously retained a six-digit number in

memory. The number was presented for 30 s prior to the

scrambled sentences and participants reported it after

unscrambling all sentences. Seventy-nine percent of par-

ticipants correctly recalled at least five digits. Participants

who recalled fewer digits were retained because poor recall

was weakly related to depressive symptoms, r = .06,

p = .28, and did not differ significantly between dysphoric

and non-dysphoric groups, v2 (1) = 2.23, p = .14

(Wenzlaff and Bates 1998). A practice session involving

three neutral sentences with a cognitive load preceded the

task. Proportion of negative to total solutions constituted

the variable scores. The SST has reliably discriminated

between depressed and non-depressed participants in sev-

eral studies (e.g., Rude et al. 2003).

Explicit Dysfunctional Beliefs

The Dysfunctional Attitudes Scale (DAS-A; Weissman and

Beck 1978) includes 40 dysfunctional beliefs that may

influence a person’s self-evaluation (e.g., ‘‘I am nothing if a

person I love doesn’t love me’’). Participants endorsed each

belief on a scale from 1) totally disagree to 9) totally agree.

Variable scores were calculated by summing items

(a = .95).

Implicit Memory Bias

A word-stem completion task (WSCT) using perceptual

encoding assessed implicit memory biases. Two lists of

nine positive state or trait adjectives (e.g., talented) and two

lists of nine negative adjectives (e.g., miserable) were

created from words used in previous research (e.g., Bradley

and Mathews 1983) and matched on numbers of syllables.

One positive and one negative list were combined to form

an encoding list. Following a fixation cross (800 ms),

encoding list words were presented individually on screen

for 7 s in random order. On a scale from 0 to 8, participants

indicated the number of letters in each word that contained

closed parts (e.g., d, p, b, q). After a filler task, all word

lists were presented as three letter word stems. Participants

completed them with the first words that came to mind. The

difference between number of primed and unprimed neg-

ative words completed provided an index of negative

memory bias. Primed minus unprimed positive words

represented an index of positive memory bias.

Explicit Memory Bias

A free-recall task assessed explicit memory biases. Two

word lists were created as per the lists for the implicit

memory task. The six lists used in both implicit and explicit

memory tasks did not differ in length, usage frequency and

emotionality, all Fs \ 0.50. Following a fixation cross

(800 ms), nine positive and nine negative state or trait

adjectives were presented individually for 7 s in random

order. Participants were asked to memorise the words and to

rate each word’s meaning from 1) very unpleasant to 7) very

pleasant. Following a filler task, participants typed all words

they could remember from the presented series. Numbers of

positive and negative words recalled represented measures

of positive and negative memory bias, respectively.

Depression and Mood Measures

Depression

Severity of current depression symptomatology was

assessed by the Zung Self-Rating Depression Scale (ZDS;

Zung 1965). Participants indicated how often they experi-

enced each of 20 depression symptoms over the previous

two weeks, from 1) a little or none of the time to 4) most or

all of the time. Variable scores were calculated by sum-

ming item scores. The ZDS correlates moderately to highly

with other depression measures and Zung’s (1986) rec-

ommended cut-off score of 50 has reliably discriminated

depressed from non-depressed groups. For example, Turner

and Romano (1984) found the ZDS correlated .86 with the

Beck Depression Inventory and the cut-off score of 50

correctly classified 82% of participants according to clini-

cally diagnosed depression status. The ZDS was highly

reliable in the current study (a = .89 at Times 1 and 2).

Depression Groups and Status

Participants were classified as currently dysphoric if they

scored C50 on the ZDS; never-depressed if they answered

negatively to a yes/no question regarding previous diag-

nosis and scored\50 on the ZDS; and dysphoric at follow-

up if their ZDS-T2 scores were C50.

Sad Mood Induction and Mood Ratings

In accordance with previous cognitive reactivity research,

we included a procedure to sadden participants’ moods (see

Scher et al. 2005). Participants visualised a past unpleasant

event, wrote brief responses to four questions regarding

the event’s sensory, perceptual and semantic elements

(Neumann and Philippot 2007) and graded its degree of

unpleasantness. They then rated their moods on two visual

analogue scales ranging from 1) not at all happy to 100)

extremely happy and 1) not at all sad to 100) extremely sad.

Variable scores were calculated by averaging happy and sad

scores after reverse-scoring sad scores. Mood-ratings pro-

vided by a sub-sample before (M = 62.54) and after

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(M = 56.82) the induction indicated that it successfully

saddened moods, t(154) = 3.96, p \ .001, d = 0.26. A

‘‘sad mood top-up’’ question seeking further information

about the sad recollection was inserted between the groups

of implicit and explicit measures. To comply with ethical

requirements, 54 individuals who answered affirmatively to

a suicidal ideation question were automatically excluded

from the procedure by the computer software.

Procedure

Data were collected by two web-based surveys. The first

survey contained a series of implicit and explicit measures of

depression-related cognitions. Forward progression through

the survey was enforced. Participants initially completed

measures of current and past depression, followed by the

negative mood induction. Implicit measures were presented

prior to explicit measures because we considered initial

completion of explicit measures may influence subsequent

responses to implicit measures employed in this study

(Wittenbrink and Schwarz 2007). Additionally, we consid-

ered one implicit measure (SST) to be more transparent than

the other implicit measures and likely to influence sub-

sequent responses. Consequently, the NLPT and WSCT

were presented in counterbalanced order prior to the SST. A

filler task was inserted after the implicit measures to mini-

mize cross-priming of subsequent measures. The explicit

measures were then presented in counterbalanced order

following the sad mood top-up. Demographics questions

were inserted as filler items between the encoding and

completion sections of the WSCT and between the learning

and retrieval sections of the free-recall task.

Three months later, participants were invited to com-

plete a follow-up survey that assessed depressive symp-

toms. Drop-out analyses revealed that the 146 individuals

who declined to participate at Time 2 were significantly

younger (M = 27.77) than the 160 follow-up participants,

M = 31.87, t(304) = 3.40, p = .001, d = 0.39, but did not

differ on gender, years of education, relationship status or

on all study variables (i.e., mood, depression and cogni-

tive). They also did not differ on membership of the cog-

nitive profiles that emerged from the initial LPA of the

whole sample (reported below), t(304) = -0.87, p = .38.

The high attrition rate may reflect the absence of incentives

offered for Time 2 participation.

Statistical Methods

LPAs were conducted using MPlus 4.1 (Muthen and Muthen

2006) to classify participants according to patterns in the

strength and valence of their implicit and explicit cognitive

biases. When assessing model fit, particular emphasis was

given to the Bayesian information criterion (BIC, Schwartz

1978), the Lo-Mendell-Rubin likelihood ratio test (LMR,

Lo, Mendell, and Rubin 2001) and the bootstrapped likeli-

hood ratio test (BLRT, McLachlan and Peel 2000). The best

fitting model for a dataset is indicated by the smallest BIC

value generated amongst competing models. The LMR and

BLRT assess difference in goodness-of-fit between model

k and model k - 1, where k refers to the number of retained

profiles. A significant p value indicates that model k fits the

data better than model k - 1. All cognitive variables were

standardized to a mean of 50 with a standard deviation of 10

(T Scores) to facilitate interpretation of the profiles. Using

SPSS 17, we performed logistic regressions to assess the

ability of the sample profile solution and the eight cognitive

indicators to predict future depression, and conducted

ANOVAs to identify characteristics of the profiles that

emerged from both LPAs.

Results

Participants’ self-reported depressive symptoms ranged

from low to moderate (ZDS = 22–65) and the mean ZDS

score of 40 approximated the expected mean of 39 in a

non-clinical sample (Zung 1986). Missing values were

observed on implicit positive and negative memory, and

implicit self esteem (between 1% and 2%). SST responses

were excluded if the valence of an unscrambled sentence

was ambiguous, and total scores were treated as missing

data if less than 60% of the sentences were meaningfully

unscrambled (9.8%). All missing values were imputed

using the expectation maximization algorithm in SPSS 17.

Square root transformations were applied to the ZDS and

SST variables to correct positive skew. Correlations

between the measures are presented in Table 1.

LPA of the Total Sample

Fit indices for one through five profile solutions appear in

Table 2. With the smallest BIC and significant LMR and

BLRT values, the three-profile solution emerged as the best

fitting model for the data. Characteristics of the three

cognitive profiles are depicted in Fig. 1.

Profile 1 comprised 64 (21%) participants who were

characterized by generally negative (GNEG) biases on both

negative (i.e., explicit and implicit negative memory and

dysfunctional beliefs) and positive (i.e., implicit and

explicit positive memory and self-esteem) cognitive indi-

cators. That is, this group scored above average on

most negative indicators and below average on most

positive cognitions. In contrast, the 119 (39%) participants

categorized as Profile 3 demonstrated generally positive

(GPOS) cognitive biases by scoring average or above

average on all positive cognitive indicators and below

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average on all negative cognitions. Profile 2 contained 123

(40%) participants who displayed an intermediate cogni-

tive profile (GINT), by exhibiting less extreme values on

most cognitive indicators than the other groups. Significant

differences among the three profiles were observed on all

cognitive indicators except implicit positive memory.

Means, standard deviations and group differences are pre-

sented in Table 3.

The Sample Profiles and Depression

ANOVA revealed that membership of the profile solution

was significantly associated with current depressive

symptoms, F(2,303) = 91.54, p \ .001. Participants

belonging to GNEG scored significantly higher on the ZDS

than GINT members, who in turn reported more depressive

symptoms than members of GPOS. Consistent with

hypothesis (1a), GNEG comprised the most severely

dysphoric participants and GPOS included the least dys-

phoric participants. At time 1, GNEG’s mean ZDS score of

49 fell one point short of the cutoff for clinical depression

(Zung 1986). However, score distributions indicated that

52% of this group exceeded the cutoff, including 27% with

moderate levels of depressive symptoms (ZDS 56–65),

whereas mean ZDS scores for the GPOS and GINT groups

were in the non-depressed range and only 4 and 15% of

members reported mild dysphoria (ZDS 50–55 and 50–56),

respectively (Zung 1986).

We conducted a logistic regression (LR) to determine

whether profile membership would predict clinical

levels of depressive symptoms assessed 3 months later.

Future depression status was assessed dichotomously,

where 1 = non-dysphoric (ZDS \ 50) and 2 = dysphoric

(ZDS C 50). We treated depression as a dichotomous

variable because theories of cognitive vulnerability to

depression are primarily concerned with factors conferring

risk for future depression onset or escalation, rather than

increases in symptoms that may still be within the normal

range.2 Profile membership was dummy coded with GPOS

serving as the contrast group. After controlling for current

mood and depression status, the future depression model

was statistically reliable, v2 (2) = 6.21, p \ .05, Nage-

lkerke R2 = .35. The latent profile variables explained a

significant 4.4% of the total variance in future depressive

status. Supporting models of cognitive vulnerability to

depression and our second hypothesis, membership of

Table 1 Correlations between cognitive indicator and depression variables

Variables 1 2 3 4 5 6 7 8 9 10

1. Explicit negative memory .37** .01 .06 .01 -.14 .20 .00 .16 .09

2. Explicit positive memory .36** -.24 .20 .06 .14 -.30* .10 -.12 -.17

3. Explicit dysfunctional beliefs .13* -.08 -.64** -.18 -.11 .66** -.14 .55** -.09

4. Explicit self-esteem -.09 .07 -.67** .07 -.06 -.67** .10 -.49** -.10

5. Implicit negative memory .01 .02 .12* -.12* .30* .02 -.08 -.09 .43**

6. Implicit positive memory -.01 .14* -.03 .02 .09 -.01 .04 -.02 .04

7. Implicit dysfunctional beliefs .11* -.12* .63** -.66** .13* -.06 -.15 .61** .22

8. Implicit self-esteem -.03 .01 -.06 .12* -.11 .03 -.12* -.15 -.37*

9. Current depression (Time 1) .08 -.10 .57** -.64** .17** -.09 .61** -.11 .31

10. Future depression (Time 2) .10 -.10 .36** -.50** .20* -.11 .48** -.17* .71**

Values below and above the diagonal refer to the total sample (N = 306) and the depressed sub-sample (n = 57), respectively. * p \ .05,

** p \ .01

Table 2 Model fit indices for profile solutions

Profile solution BIC LMR BLRT

LPA 1: Total sample (N = 306)

1 7,030.69 – –

2 6,780.00 .01 .00

3 6,714.61 \.001 .00

4 6,722.77 .10 .00

5 6,733.01 .13 F

LPA 2: Dysphoric sub-sample (n = 57)

1 1,338.28 – –

2 1,314.19 .04 .00

3 1,319.44 .64 .03

4 1,332.31 .40 .16

5 1,343.01 .46 F

BIC = Bayesian information criterion, LMR = Lo-Mendell-Rubin

likelihood ratio test, BLRT = Bootstrapped likelihood ratio test,

F = failed to converge

2 We also conducted hierarchical multiple regressions predicting

continuous Time 2 depression scores (ZDS-T2) from: (1) the GPOS-

GNEG and GPOS-GINT dummy variables and, (2) the eight cognitive

variables after controlling for ZDS-T1 and mood at the first step. Both

models were significant: (1), R2 = .53, F(4,151) = 42.38, p \ .001;

(2) R2 = .55, F(10,145) = 17.80, p \ .001. However, the dummy

variables and cognitive indicators did not significantly predict ZDS-

T2 at the second steps of their respective models: (1) R2 = .01,

F(2,151) = 1.32, p = .27; (2) R2 = .03, F(8,145) = 1.23, p = .29.

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GNEG significantly predicted future depression status,

Wald = 5.21, B = 2.03, p = .02, but GINT membership

did not, Wald = 2.28, B = 1.25, p = .13. The odds of

being categorised as dysphoric at Time 2 were 7.63 times

greater for GNEG than for GPOS members.3 The model

correctly classified 85.9% of participants as dysphoric or

non-dysphoric.

Explicit negative memory Explicit positive memory Explicit dysfunctional beliefs Explicit self-esteem

Implicit negative memory Implicit positive memory Implicit dysfunctional beliefs Implicit self-esteem

Generally negative Intermediate Generally positive n = 64 n = 123 n = 119

Mea

n T

Sco

res

65

60

55

50

45

40

35

Fig. 1 Cognitive bias means by

profile for the total sample.

Error bars: ±1 SE

Table 3 Means and standard deviations for cognitive indicators, age and depressive symptomatology across the three profiles from the total

sample

Variables Profile 1 Profile 2 Profile 3

Generally negative Intermediate Generally positive

n = 64 (37) n = 123 (63) n = 119 (60)

M SD M SD M SD

Explicit negative memory* 50.15ab 9.47 51.89b 10.12 47.97a 9.84

Explicit positive memory* 45.67a 8.87 52.01b 9.74 50.26b 10.20

Explicit dysfunctional beliefs* 63.24a 6.95 49.94b 6.11 42.94c 6.98

Explicit self-esteem* 38.40a 6.75 48.52b 5.67 57.77c 8.05

Implicit negative memory* 51.39a 10.10 51.30ab 9.69 47.91b 9.98

Implicit positive memory* 48.28 9.90 50.40 8.89 50.52 11.06

Implicit dysfunctional beliefs* 63.37a 4.20 52.71b 4.50 40.01c 4.77

Implicit self-esteem* 48.71a 10.84 48.64ab 9.38 52.10b 9.88

Age 29.33 12.45 29.26 9.78 30.86 10.71

Current depression (Time 1) 49.11a 8.12 41.41b 7.29 34.02c 6.88

Future depression (Time 2) 46.60a 10.00 41.43b 8.15 33.78c 7.75

* Cognitive bias means standardized to a mean of 50 (SD = 10). ns in parentheses represent group sizes at Time 2. Group means with different

superscripts (on rows) are significantly different at p \ .05

3 To enable comparison of the profiles as predictors of current and

future depression, we also conducted logistic regressions that did not

Footnote 3 continued

control for the effects of pre-existing depression. After controlling for

mood, the odds of being categorised as dysphoric were 10.19 times

greater for GNEG than for GPOS members at Time 1 and 17.78 times

greater at Time 2. Thus, GNEG membership was more strongly

associated with future than with current depressive status.

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A subsequent sequential LR assessed the relative con-

tributions of the eight cognitive predictors to future

depression status. Current mood and depression status were

entered as covariates in the first block. We entered all

implicit cognitions in the second block and all explicit

cognitions in the third block because implicit (automatic)

cognitions are posited to occur prior to explicit (deliberate)

cognitions (e.g., Beevers 2005; Carver et al. 2008). As

shown in Table 4, the model provided good fit for the data.

Addition of the four implicit cognitions at Block 2 signif-

icantly improved model fit, v2(4) = 11.35, p = .02, and

explained an extra 10% of the variance in future depressive

status. In contrast, the addition of the four explicit cogni-

tions at Block 3 did not significantly improve model fit,

v2(4) = 1.23, p = .87, and explained only 1% of addi-

tional variance in future depression. Of the eight cognitions

assessed, only implicit self-esteem significantly predicted

Time 2 depressive status. Specifically, a one unit increase

in implicit self-esteem decreased the odds of experiencing

dysphoria 3 months later by 45%. Time 1 depressive status

and mood correctly classified 83.3% of participants as

dysphoric or non-dysphoric at Time 2. Classification

accuracy increased to 88.2% with the addition of the

implicit variables but decreased to 87.5% following addi-

tion of the explicit variables.4 Therefore, as hypothesized,

the results suggest that the set of implicit cognitions pre-

dicted future depression status more strongly than the

explicit cognitions; although the predictive power of the

implicit set was driven primarily by implicit self-esteem.

Table 4 Logistic regression of implicit and explicit cognitive indicators predicting time 2 depression status

Variables B SE B Wald p Exp (B)

Block 1: Covariates

DEP-T1 2.68 0.59 20.36 \.001 14.51

Mood-T1 0.01 0.01 0.19 .67 1.01

Block/model: v2(2) = 29.85, p \ .001, R2 = .30

Block 2: Implicit cognitions

DEP-T1 (Block 1) 2.52 0.66 14.48 \.001 12.45

Mood-T1 (Block 1) 0.01 0.01 0.88 .35 1.01

IMNEG 0.14 0.19 0.57 .45 1.15

IMPOS -0.07 0.17 0.18 .67 0.93

SST 0.18 0.12 2.14 .14 1.20

NLPT -0.80 0.36 4.95 .03 0.45

Block: v2(4) = 11.35, p = .02; Model: v2(6) = 41.21, p \ .001, R2 = .40

Block 3: Explicit cognitions

DEP-T1 (Block 1) 2.46 0.69 12.76 \.001 11.65

Mood-T1 (Block 1) 0.01 0.02 0.88 .35 1.01

IMNEG (Block 2) 0.15 0.19 0.62 .43 1.16

IMPOS (Block 2) -0.07 0.18 0.15 .70 0.93

SST (Block 2) 0.07 0.17 0.19 .66 1.08

NLPT (Block 2) -0.81 0.36 4.94 .03 0.45

EMNEG -0.11 0.24 0.23 .63 0.89

EMPOS -0.05 0.19 0.06 .81 0.95

DAS 0.00 0.01 0.15 .70 1.00

RSE -0.04 0.07 0.39 .53 0.96

Block: v2(4) = 1.23, p = .87; Model: v2(10) = 42.43, p \ .001, R2 = .41

R2 = Nagelkerke R2, DEP-T1 = time 1 depression status (1 = non-depressed, 2 = depressed), Mood-T1 = mood after mood induction,

IMNEG = implicit memory for negative stimuli, IMPOS = implicit memory for positive stimuli, SST = scrambled sentences task,

NLPT = name letter preference task, EMNEG = explicit memory for negative stimuli, EMPOS = explicit memory for positive stimuli,

DAS = dysfunctional attitude scale, RSE = rosenberg self-esteem scale

4 We conducted a second sequential logistic regression in which

explicit cognitions were entered in the second block and implicit

cognitions in the third block. Despite their earlier entry in this

analysis, the explicit variables failed to explain a significant amount

of variance in future depressive status (4.5%, p = .28). After

controlling for explicit cognitions, the implicit block explained

6.5% variance; but this also fell short of significance (p = .11). We

considered that the results of both sequential regressions, together,

indicated greater predictive power from implicit than explicit

cognitions. Consequently, we elected to report the significant results

of the theoretically driven analysis.

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LPA of Currently Dysphoric Participants

LPA of participants classified as currently dysphoric

(ZDS C 50, n = 57) indicated that a two profile solution

provided an optimal fit for the data. As shown in Table 2,

the two profile model produced the smallest BIC value and

significant LMR and BLRT values. Cognitive features of

the two depressive profiles are depicted in Fig. 2, along

with the profile of never-depressed participants.

Profile 2 comprised 42 (74%) dysphoric participants

who displayed average or negatively biased scores on all

cognitive indicators. This profile resembled the GNEG

profile of the sample LPA, and was primarily characterized

by low implicit and explicit self-esteem, weak explicit

positive memory, and high levels of implicit and explicit

dysfunctional beliefs. In contrast, the 15 (26%) dysphoric

participants classified as Profile 1 displayed average or

positively biased levels of all cognitions except for implicit

negative memory, which was stronger than average. We

named Profiles 1 and 2 negative memory (NEGMEM) and

schematic (SCHEM), respectively.

ANOVAs with post-hoc comparisons assessed differ-

ences between each depressive profile and the cognitive

biases of a never-depressed sub-sample (n = 188). Means,

standard deviations and group differences are presented in

Table 5. Members of SCHEM displayed significantly

greater negative biases than never-depressed participants

on five of the eight indicators. In contrast, individuals

belonging to NEGMEM differed significantly from the

never-depressed group only in their demonstration of

greater implicit negative memory.

The Dysphoric Profiles and Depression

Individuals belonging to the SCHEM profile exhibited

more depressive symptoms than members of NEGMEM,

F(1,55) = 11.60, p = .001, d = 0.70. NEGMEM’s ZDS

scores (range 50–55) indicated that all members reported

mild levels of depression, whereas SCHEM’s scores (range

50–65) revealed that it comprised moderately depressed

individuals (Zung 1986).

Discussion

According to dual-process models of cognitive vulnera-

bility to depression, implicit and explicit information pro-

cessing systems interact to precipitate depression (Beevers

2005; Carver et al. 2008; Haeffel et al. 2007). These per-

spectives imply that vulnerable individuals possess cogni-

tive profiles comprising multiple negative implicit and/or

explicit cognitive biases that may take either a quantitative

or a qualitative form. To help clarify the nature of dual-

process depressive cognitive profiles within an under-

graduate sample, we conducted an LPA of four implicit

and four explicit depression-related cognitions and tested

the ability of the profile solution to predict clinical levels of

depressive symptoms assessed 3 months later. We also

conducted an LPA of cognitive biases observed in a dys-

phoric sub-sample of participants to investigate the possi-

ble existence of dual-process cognitive subtypes of

depression.

Mea

n T

Sco

res

65

60

55

50

45

40

35Dysphoric Profile 1 Dysphoric Profile 2 Never depressed Negative implicit Negative beliefs & n = 188

memory self-esteem n = 15 n = 42

Explicit negative memory Explicit positive memory Explicit dysfunctional beliefs Explicit self-esteem

Implicit negative memory Implicit positive memory Implicit dysfunctional beliefs Implicit self-esteem

Fig. 2 Means for the two

dysphoric group profiles

compared to the never-

depressed group. Error bars:

±1 SE

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Emergent patterns of implicit and explicit cognitions

from the LPA of the total sample (N = 306) were best

described by three cognitive profiles that reflected a

dimensional progression from generally negative, through

intermediate, to generally positive biases. Twenty-one

percent of participants classified as GNEG attained high

mean scores on most indicators of negative cognitions

(i.e., implicit and explicit dysfunctional beliefs and nega-

tive memory) and low scores on all positive cognitions

(i.e., implicit and explicit self-esteem and positive mem-

ory). An inverse pattern of biases was exhibited by the 39%

of participants belonging to GPOS, who displayed high or

average levels of most positive cognitions and low levels of

all negative cognitions. Biases displayed by 40% of the

sample classified as GINT were generally less extreme than

the other two profiles and conveyed a slightly negative

overall bias. As predicted by cognitive theories of

depression, GNEG members were significantly more

dysphoric than GINT members, who in turn were more

dysphoric than GPOS members.

In contrast, the LPA of our dysphoric sub-sample

(n = 57) produced a categorical solution. Two strikingly

different patterns of responses across indicators emerged,

which may represent cognitive subtypes of depression. To

identify clinically meaningful features, we compared these

profiles with the cognitive profile of a pre-selected group of

never-depressed participants. Like the GNEG profile

observed in the total sample, most dysphoric participants

demonstrated schematic negative biases on most cogni-

tions. In contrast, the profiles of 26% of dysphoric

participants were similar to those of never-depressed par-

ticipants in every respect except for significantly higher

scores on implicit negative memory. Validation of the two

profile solution against the ZDS revealed that NEGMEM

comprised individuals whose symptoms indicated mild

depression whereas SCHEM included all participants

whose symptoms indicated moderate depression (Zung

1986).

Theoretical Predictions and Implications

The progressive shift in cognitive biases from negative to

positive across the three profiles that emerged from the

initial LPA supports our hypothesis (1a), that heterogeneity

of implicit and explicit cognitive biases associated with

depression would take a quantitative form. This result is

compatible with previously observed dimensional distri-

butions of explicit depressive cognitions (Gibb et al. 2004)

and depressive symptoms (e.g., Ruscio and Ruscio 2002) in

unspecified samples, and with the finding that implicit

interpretations of ambiguous stories ranged from positive

to negative across groups of participants whose depressive

symptoms ranged from low to high (Halberstadt, et al.

2008). The existence of dimensional dual-process cognitive

profiles is consistent with the dual-process theoretical

proposition that depressive symptoms may occur when

negative explicit cognitions reflect underlying negative

implicit cognitions (Beevers 2005; Carver et al. 2008).

However, it should be noted that other interpretations are

equally viable. Most notably, the profile solution is also

Table 5 Means and standard deviations for cognitive indicators, age and depressive symptomatology across the two depressive profiles and the

never-depressed sub-sample

Variables Depressive profiles

Negative memory Schematic Never-depressed

n = 15 (7) n = 42 (30) n = 188 (86)

M SD M SD M SD

Explicit negative memory* 50.92 9.58 50.92 9.45 49.39 10.31

Explicit positive memory* 53.37a 8.82 44.95b 9.38 50.89a 9.82

Explicit dysfunctional beliefs* 48.00a 6.99 62.17b 8.53 47.33a 8.33

Explicit self-esteem* 51.50a 7.99 37.91b 6.82 52.70a 8.50

Implicit negative memory* 55.85a 10.27 51.42ab 9.44 49.64b 10.26

Implicit positive memory* 49.75 12.49 50.20 10.59 50.58 10.12

Implicit dysfunctional beliefs* 47.25a 6.22 62.50b 5.43 47.41a 8.89

Implicit self-esteem* 52.26 5.10 46.76 11.84 50.94 9.97

Age 34.13 11.97 29.29 11.24 28.37 9.57

Current depression (Time 1) 51.93a 1.75 55.24a 3.59 36.44b 6.78

Future depression (Time 2) 47.43a 10.23 49.03a 8.70 36.31b 8.44

* Cognitive bias means standardized to a mean of 50 (SD = 10). ns in parentheses represent group sizes at Time 2. Group means with different

superscripts are significantly different at p \ .05

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consistent with the existence of a single system of

depressive processing.

Accordingly, the LPA failed to support our categorical

dual-process hypothesis (1b) which predicted the emer-

gence of qualitatively distinct cognitive profiles, including

a vulnerable profile comprising negative implicit and

positive explicit cognitive biases. This outcome is at odds

with neurophysiological and behavioural evidence sug-

gesting that effortful processing can override negative

implicit processing when sufficient resources are available

(for reviews, see Beck 2008; Beevers 2005; Carver et al.

2008; Scher et al. 2005). The absence of qualitative cog-

nitive profiles is particularly discordant with previous

studies of self-esteem in depression. For example, depres-

sion-related fluctuations in explicit self-esteem (Franck and

De Raedt 2007) and discrepancies between implicit and

explicit self-esteem (Schroder-Abe et al. 2007) support the

notion that some individuals possess conflicting levels of

these constructs. Thus, further research is needed to

investigate the role of implicit and explicit self-esteem in

depression.

An essential feature of all models of cognitive vulner-

ability to depression is that high-risk cognitions can exist in

the absence of symptoms and precede depression onset or

recurrence (Abramson et al. 1989; Beck 1987; Beevers

2005; Haeffel et al. 2007; Ingram 1984). Supporting this

premise and our second hypothesis, logistic regression

revealed that GNEG members were seven times more

likely than GPOS members to experience clinical levels of

depressive symptoms 3 months later, even after controlling

for current depression status and mood. This result suggests

that possession of a GNEG cognitive profile may account

for variance in future depression that cannot be explained

by current depression and mood. Thus, our finding may

offer unique (predictive) support for the theoretical notion

that cognitive vulnerability to depression involves sys-

tematic negative biases in all self-referential thoughts and

information processes (Beck 1987; Bower 1981; Ingram

1984; Teasdale 1988).

Previous research has observed predictive relationships

between individual negative cognitions (e.g., explicit dys-

functional beliefs) and subsequent depression; albeit

inconsistently (for review, see Joormann 2009). However,

to our knowledge, no prior study has simultaneously

assessed as many as eight cognitions. Our sequential

logistic regression of the four implicit and four explicit

cognitive variables revealed that the set of implicit cogni-

tions explained a significant 10% of the variance in future

depressive status over and above the contributions of cur-

rent depression and mood, but adding the set of explicit

cognitions did not significantly improve model fit.

Furthermore, similar (although less pronounced) results

emerged when explicit cognitions were entered prior to

implicit cognitions. Therefore, the results provided some

support for our third hypothesis and the view that negative

implicit cognitions confer greater cognitive vulnerability to

future depression than negative explicit cognitions (e.g.,

Beevers 2005). However, of the eight cognitions assessed,

only implicit self-esteem significantly predicted subsequent

depressive status; where high implicit self-esteem was

associated with reduced likelihood of experiencing dys-

phoria 3 months later. This observed relationship is con-

sistent with most, but not all, previous studies of implicit

self-esteem in depression (see Phillips et al. 2010). Overall,

the results of the sample LPA and logistic regressions

suggest that explicit cognitions are more closely associated

with current depression and implicit cognitions are stronger

predictors of future depression.

The possible identification of a negative memory cog-

nitive subtype of depression is particularly interesting

given the importance of memory in most theories of cog-

nitive vulnerability to depression. Beck (1987) and Bower

(1981) proposed that depressive schemas comprise nega-

tive memory representations that bias information pro-

cessing toward negatively valenced stimuli, and Ingram

(1984) and Teasdale (1988) proposed that depressed mood

increases the accessibility of representations of depressing

experiences and constructs. A variety of empirical studies

support these perspectives. For example, varying mood

inductions (e.g., sad, happy, angry) have been associated

with parallel shifts in mood and representations in working

memory (Siemer 2005). Consequently, mild depression

experienced by individuals belonging to NEGMEM may

reflect activated memory networks associated with low

mood, but may not involve the spreading activation that is

purportedly characteristic of clinical depression (Bower

1981; Ingram 1984; Teasdale 1988).

However, a more intriguing interpretation of the nega-

tive memory profile is suggested by dual-process theories

of cognitive vulnerability to depression (Beevers 2005;

Carver et al. 2008; Haeffel et al. 2007). Memory is an

essential component of these accounts. Depressive cogni-

tions are posited to originate at an implicit level; where

processing is guided by similarities between a current

stimulus and memory associations that have developed

slowly over time through repeated experience (Beevers

2005). These associations are believed to pre-consciously

influence the subsequent processing and interpretation of

new information at both implicit and explicit levels (Smith

and DeCoster 2000). Therefore, although speculative,

NEGMEM may represent the early stages of depressive

onset; where implicit negative memory biases precede or

activate other implicit and explicit depressive cognitions.

Future longitudinal research may investigate this pos-

sibility by reassessing cognitive biases at follow-up to

identify which biases behave like symptoms of disorder

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(i.e., returning to normal/positive following recovery) and

which cognitions remain relatively stable despite decreases

in depressive symptoms. Stability of negative biases before

and/or after a depressive episode may be indicative of

cognitive vulnerability. Several studies have investigated

the stability of depressive cognitions (e.g., Dozois and

Dobson 2001); however, they did not statistically assess the

relative stability of conceptually similar output from both

processing systems (e.g., implicit vs. explicit self-esteem).

Prospective research that elucidates mechanisms

underlying the hypothesized dual-process interaction is

also needed. To date, two studies have directly addressed

dual-process diathesis-stress hypotheses and found con-

flicting results. Haeffel et al. (2007) found that explicit

cognitive styles conferred greater vulnerability than

implicit self-esteem to depressive symptoms five weeks

later for undergraduates who experienced high life stress.

In contrast, Steinberg et al. (2007) found a greater pre-

dictive contribution from implicit self-esteem assessed by

the Implicit Association Task (Greenwald and Farnham

2000) toward future depression in the presence of life stress

amongst undergraduates who scored highly on measures of

explicit depressive cognitions.5 Study designs employing

participant groups that differ in their capacity to utilise

explicit corrective processing may effectively assess the

hypothesized dual-process interaction.

Treatment Implications

Our initial LPA solution suggests that some cognitive

biases are more reliable discriminators of current depres-

sive symptoms than others. Significant decreases in

depressive symptoms across the profiles were reflected in

dramatic and regular increases in explicit self-esteem and

decreases in implicit and explicit dysfunctional beliefs.

Thus, our results validate the approach of the most widely

used intervention, Cognitive Therapy (Beck et al. 1979),

which aims to modify explicit negative beliefs by inter-

rupting thought patterns associated with depression. How-

ever, although this treatment is strongly associated with

immediate symptomatic improvement, 2 year recurrence

rates can be as high as 73% for certain patient groups (Tang

et al. 2007). We found that participants with cognitive

profiles featuring both implicit and explicit negatively-

biased cognitions were at high risk of experiencing clinical

levels of depressive symptoms 3 months later, and that

possession of negative implicit cognitions, especially low

implicit self-esteem, conferred greater vulnerability to

future depression than negative explicit cognitions. These

results suggest that long-term treatment efficacy may be

improved by incorporating strategies that address implicit

processes.

Beevers (2005) described three ways to target implicit

processing. First, therapies could aim to change conscious

expectancies so that corrective explicit processing is trig-

gered in response to negative implicit responses. For

example, Mindfulness Based Cognitive Therapy (Segal

et al. 2002) aims to help recovered depressed individuals to

become aware of unwanted thoughts, feelings and body

sensations, and to disengage from negative thinking pat-

terns by changing their responses from automatic or

avoidant to intentional and skilful. Second, strategies could

aim to change patterns of activation determined by asso-

ciative network structures by repeatedly engaging in cor-

rective explicit processing. For example, repeatedly

preventing memories from entering awareness has been

shown to impair their subsequent deliberate recollection

(Anderson and Green 2001) and a procedure to train

depressed individuals to forget negative material was

recently developed (Joormann et al. 2009). Third, therapies

could incorporate both affective and cognitive strategies to

relearn implicit associations and explicit interpretations.

For example, Emotion-Focused Therapy (Greenberg and

Watson 2005) and Exposure-Based Cognitive Therapy

(Hayes et al. 2005) aim to generate new cognitive struc-

tures by focussing on emotional experiences and the

meanings attributed to them.

Limitations

Several limitations of this study should be taken into

account when interpreting its results. First, the generalis-

ability of these results may be limited by our relatively

small, predominantly mature-aged, undergraduate sample

and substantial attrition rate at Time 2. It is also probable

that the small follow-up sample underpowered the logistic

regression of the eight cognitive indicators, and that

stronger effects may be observed in a larger sample.

Additionally, the small dysphoric sub-sample may have

limited the power to detect subgroups in the dysphoric

group analysis. Second, control of environmental factors

during survey completion was not possible due to our web-

based data-collection medium. Third, participants’

depression status was determined by self-report because the

preferred method of classification by formal diagnosis was

not practicable. Fourth, this study did not consider the

effects of life stress, which are hypothesized to play an

integral role in models of cognitive vulnerability to

depression. Lastly, we classified the SST as an implicit

measure because it involves the automaticity features of

fast and efficient (see, Moors et al. 2010). However, its

5 Steinberg et al. (2007) found no significant effects when implicit

self-esteem was assessed by the NLPT. However, their scoring

procedure did not include an algorithm to control for individual

differences in baseline responses (LeBel and Gawronski 2009) which

may have affected the measure’s validity.

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relative transparency may overlap with explicit measures in

the consciousness and control of participants’ responses

(Wenzlaff et al. 2001).6 Thus, its role as an implicit mea-

sure should be considered with caution.

Conclusion

LPA of unselected undergraduates identified three dual-

process cognitive profiles comprising compatible levels of

implicit and explicit cognitive biases ranging from nega-

tive, through intermediate, to positive. This quantitative

distribution is consistent with the dual-process notion that

negative explicit cognitions and depressive symptomatol-

ogy may occur when negative implicit processing remains

uncorrected by explicit processing. The LPA produced

little evidence to support the alternative dual-process

implication that some individuals possess conflicting

implicit and explicit self-cognitions that place them at

greater risk for depression. Patterns of biases across the

profiles were associated with decreases in current depres-

sive symptoms and membership of the negative profile

significantly predicted clinical levels of depressive symp-

toms 3 months later. Implicit self-esteem emerged as the

strongest predictor of subsequent dysphoria, and the like-

lihood of future dysphoria was more strongly influenced by

the set of four implicit self-cognitions than the set of

explicit cognitions. Our dysphoric group LPA identified a

possible cognitive subtype of depression that was charac-

terized by heightened implicit memory for negative stimuli

but was otherwise positive. Further research is needed to

determine whether this profile represents a distinct form of

mild depression or a precursor to more severe forms of

depression. Overall, our results are consistent with the

dual-process premise that two types of cognitive processes

are involved in depression; suggest that cognitive therapies

should incorporate strategies that target implicit cognitions;

and highlight the need for further investigations into the

roles of implicit and explicit processes in depression.

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