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Stephen E. Fish, Ph.D.

Mitchell L. Berk, Ph.D.

Marshall University J. C. E.

School of Medicine

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Note to instructors:

I use these PowerPoint slides in histology lectures that I give to

first year medical students. Copy the slides, or just the images

into your own teaching media. We all know that teaching science

often requires compromises and simplification for specific

student populations, or the requirements of a specific course.

Please feel free to offer suggestions for improvements,corrections, or additional illustrations. I would be pleased to hear 

from anyone who finds my work useful, and am always willing to

make it better. Also, the images have been compressed to screen

resolution to keep PowerPoint file size down, and I can provide

them at any resolution. Contact me about the illustrations and

Mitchell L. Berk about the photomicrographs.

Stephen E. Fish, Ph.D.

Fish@Marshall.edu

Berk@Marshall.edu

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Urinary system

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Kidney overview

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Kidney overview

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Nephrons are the functional

unit of the kidney

Nephron

 ± Glomerulus

 ± Proximal convoluted

tubule

 ± Loop of Henle

 ± Distal convoluted tubule

Uriniferous Tubule

 ± Nephron

 ± Collecting tubule & duct

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Cortical vs. juxtamedullary nephrons

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Glomerulus

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Renal corpuscle

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Podocytes team up to make

filtration slits

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Building an ultrafiltration barrier 

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Getting the scale correct, as might be

seen in an EM photograph

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When a filter gets dirty it must be

cleaned- mesangial cells are the janitors

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Renal corpuscle

Collecting tubule

Medullary ray

Proximal & distalconvoluted tubules

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Proximal tubule cells

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The thin limb of the loop of Henle

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Thin limbs of the loop of Henle

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Histologically the ascending thick limb & the

distal convoluted tubules are the same

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Collecting tubule

Thick

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Distal convoluted (shorter)

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Glomerulus

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Collecting tubules

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Collecting tubulesHow about

thick and

thin limbs

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Collecting duct

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Collecting ducts (of Bellini)

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Ducts exiting at the area cribrosa on the papilla

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Arteries, veins & lobes

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More vasculature & lobules

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Kidney capillaries

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Large lobar artery entering

from medulla

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Intermediate size arcuate at border 

of cortex and medulla

Cortex with

Corpuscles &

Convoluted tubes Medulla with

straight tubes

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Interlobular (running up in

middle of lobule

between corpuscles

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Minor calyx

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Transitional epithelia

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Calyx epithelia

Dome cells

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Ureter 

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Circular smooth

muscle

Longitudinal

smooth muscle

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Dome cells

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Urinary Bladder 

Bundles

of 

smooth

muscle

Dense irregular CT

Transitional

epithelium

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Transitional epithelia changes depending

on how full the urinary bladder is

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Transitional epithelia membrane

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