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7/28/2019 2 Energy and Thermodynamics
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Topics
1. Introduction
2.Energy and thermodynamics
3.Feeding and ingestion
4. Ionic gradient, electrical potential
5.Electrical signals and neurons
6.Locomotion, muscle and skeleton
7.Heat production and body temperature
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Reading assignment
Energy and life
http://hyperphysics.phy-astr.gsu.edu/hbase/biology/enercyc.html
Thermodynamics
http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookEner1.html
Biological system and thermodynamics
http://www.bio.net/bionet/mm/neur-sci/1995-July/019223.html
Obesity
http://www.nlm.nih.gov/medlineplus/obesity.html
Food label and calorie information
http://www.nutritiondata.com/
Which exercise burns more calorie?
http://www.healthcentral.com/diet-exercise/quizzes-251185.html
http://hyperphysics.phy-astr.gsu.edu/hbase/biology/enercyc.htmlhttp://www.estrellamountain.edu/faculty/farabee/biobk/BioBookEner1.htmlhttp://www.bio.net/bionet/mm/neur-sci/1995-July/019223.htmlhttp://www.nlm.nih.gov/medlineplus/obesity.htmlhttp://www.nutritiondata.com/http://www.healthcentral.com/diet-exercise/quizzes-251185.htmlhttp://www.healthcentral.com/diet-exercise/quizzes-251185.htmlhttp://www.healthcentral.com/diet-exercise/quizzes-251185.htmlhttp://www.healthcentral.com/diet-exercise/quizzes-251185.htmlhttp://www.healthcentral.com/diet-exercise/quizzes-251185.htmlhttp://www.healthcentral.com/diet-exercise/quizzes-251185.htmlhttp://www.nutritiondata.com/http://www.nlm.nih.gov/medlineplus/obesity.htmlhttp://www.bio.net/bionet/mm/neur-sci/1995-July/019223.htmlhttp://www.bio.net/bionet/mm/neur-sci/1995-July/019223.htmlhttp://www.bio.net/bionet/mm/neur-sci/1995-July/019223.htmlhttp://www.bio.net/bionet/mm/neur-sci/1995-July/019223.htmlhttp://www.bio.net/bionet/mm/neur-sci/1995-July/019223.htmlhttp://www.estrellamountain.edu/faculty/farabee/biobk/BioBookEner1.htmlhttp://hyperphysics.phy-astr.gsu.edu/hbase/biology/enercyc.htmlhttp://hyperphysics.phy-astr.gsu.edu/hbase/biology/enercyc.htmlhttp://hyperphysics.phy-astr.gsu.edu/hbase/biology/enercyc.html7/28/2019 2 Energy and Thermodynamics
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What is physiology?
Physiology deals with the (1) processes,
(2) activities and (3) phenomenaincidental
to and characteristics oflife.
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What is live?
What is death?
Why do you need a supply
of energy to be alive?
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What are living organisms made of?atoms
molecules
macromolecular complex
elementary cellular structures
organelles
cellstissues
organ systems
animal
(Chemistry)
(Biochemistry)macromolecules
(Cell Biology)
(Genetics)(Histology)
(Physiology)
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Energyis necessary to maintain
structure, but structure is in turn
necessary to utilize the energy.
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Laws of Thermodynamics
1. The amount ofenergy present in this
Universe is constant.
2. There is alwaysa certain amount ofenergy which changes into a lower quality
form such as heat and becomes less
available to do work.
(Concept of entropy)
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Different forms of energyGravitational energy
Energy of rotationEnergy of orbital motion
Energy of nuclear fission
Energy of nuclear fusionSolar energy
Sound energy
Electrical energy
Energy of chemical reaction
Chemical potential energy
Heat
Cosmic radiation
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Laws of Thermodynamics
1. The amount ofenergy present in this
Universe is constant.
2. There is alwaysa certain amount ofenergy which changes into a lower quality
form such as heat and becomes less
available to do work.
(Concept of entropy)
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Both 1st and 2nd Laws ofThermodynamics refer to observations
made on the Universe and not only the
system that we are interested in.
Universe= System +Surrounding
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SURROUNDING
SYSTEM
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Living systems would appear defy theSecond Law of Thermodynamics because oftheir high degree of maintained order.
How do you reconcile the low entropy of anorganism with this fundamental physical law?
Can the 2nd law of thermodynamics beapplied here?
egg
Highly-ordered
organism
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Ingestion of food by animal increases the entropy of
the food molecules by breaking them down intosmaller molecules of lower free energy content.
The free energy liberated is utilized by animal cells
to drive energy-requiring reactions.
H2OCO2
Nitrogenous
waste
H2O
H2O
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Initial State
Final State
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In relationship to chemical reactions, Gibbs Free
Energy(G)defines if the reaction would go
spontaneously from the initial state to the final state.
where H = change in enthalpy (heat content)
G = H - T S
G = H +(- T S)
S = change in entropy (energy that is highly
dispersed and not available to do work)
Reactions would go spontaneously in the direction of
achieving a final state of lower internal energy in the
system.
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Initial State
Final State
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Whats the meaning ofG?
-G= the maximum amount of energytheoretically available for the system to dobiological useful work on its surrounding
when the system goes from initial state tothe final state if the process is reversible.
= Exergonic
G = Gfinal - Ginitial
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+ G= the amount of energytheoreticallythesurrounding has to supply to the system so
that it can go from the initial state to the final
state
= Endergonic
G = Gfinal - Ginitial
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G = 0 = equilibrium
A + B C + D
Keq = [C] [D]
[A] [B]
IfKeqis very big, e.g. 106, we basically still assumethere is some A and some B left.
Thermodynamics deals with collections of matter.
It does not apply to several molecules. As such itsanalyses depend a lot on statistical probability.
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Under what condition will an
endergonic reaction proceed?
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ADP
C6H12O6 + 6O2COUPLE
ATP
6CO2 + 6H2O
G = +7000 cal / mole
G = -420,000cal / mole
G = -686,000cal / mole
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Biological TranducersTransformation Transducers
Chemical electrical
mechanicalChemical
Chemical osmotic
Light
Sound
electrical
electrical
Light chemical
Brain, nerve
Nose, tongue
Muscle
Kidney
Eye
Ear
Plant
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What is unique to living organisms?
The essential feature of living organisms is
their ability to capture, transformand
storevarious forms of energy accordingto the specific instructions of their
individual genetic materials.
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Photosynthesis
(leaf)CO2 + H2O O2 + C6H12O6
PLANTS
Solar
energy
Respiration (mitochonddria)
ATP
Mechanical Transport Assembly
contractionof solute of biomolecules
ADP ADP ADP
Protein
FatsCarbohydrate
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Solar energy/light
Chemical potential energy e.g. Na+ or K+ gradient
Chemical energy, ATP
Chemical energy, e.g. carbohydrate
Electrical energy, e.g. membrane potential
Heat
Heat
Heat
Heat
Chemical energy, ATP
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End
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Teaching is transmission of knowledge
to students
Instruction Paradigm
Versus
Teaching is facilitation of students
learning
Learning Paradigm
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Be an Active Listener
People speak at 100 to 175 words per minute,but they can listen intelligently at up to 300 words
per minute.
Mind-driftthinking about other things whilelistening to someone.
Listen with a purpose (gain info, obtain
directions, understand others, solve problems,
share interests, show support)
Try repeating words mentally as they say it
control mind drift.
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Topics
1. Introduction
2.Energy and thermodynamics
3.Feeding and ingestion4. Ionic gradient, electrical potential
5.Electrical signals and neurons
6.Locomotion, muscle and skeleton
7.Heat production and body temperature
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