Upload
coleen-harrison
View
224
Download
0
Embed Size (px)
DESCRIPTION
Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment
Citation preview
2004-2005Pharmacology Review
of Everything(Principles, Cardiovascular and Respiratory drugs have been
updated)
May 4, 202311:11 PM
Spectinomycin
AntibioticBacteriostatic protein synthesis
inhibitor
30S ribosome
Spironolactone
Potassium sparing diureticAntiandrogen
Aldosterone receptor antagonistAndrogen receptor antagonist
Testosterone synthesis inhibitorAntihypertensive
Heart failure treatment
St. John’s Wort
Dietary supplement
Antidepressant
Streptokinase
Thrombolytic
Streptomycin
Aminoglycoside antibioticBactericidal protein synthesis
inhibitor
30S ribosomeFreezes initiation
Succinylcholine
Paralytic
Depolarizing blockerParalyzes skeletal muscles
Bronchoconstrictor
Sucralfate
Antiulcer
Sufentanil
OpioidGeneral anaesthetic
Intravenous anaesthetic
Sulfacetamide
Sulfonamide antibioticMicrobial nucleic acid
and protein synthesis inhibitor
Inhibits dihydropteroate synthetaseTopical
Sulfadoxine
Sulfonamide antibioticMicrobial nucleic acid
and protein synthesis inhibitor
Dihydropteroate synthetase inhibitor
Sulfamethoxazole
Sulfonamide antibioticMicrobial nucleic acid
and protein synthesis inhibitor
Inhibits dihydropteroate synthetase
Sulfasalazine
Disease modifyinganti-rheumatic drug (DMARD)
Metabolized to sulfonamide+ salicylate (NSAID)
Treatment of IBD
Sulfinpyrazone
Uricosuric
Anti-gout
Sulfisoxazole
Sulfonamide antibioticNucleic acid and
protein synthesis inhibitor
Inhibits dihydropteroate synthetase
Sulfonamides
AntibioticsNucleic acid and
protein synthesis inhibitors
Inhibit dihydropteroate synthetase
Sulindac
NSAIDAnalgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Suramin
Tropical antiparasitic
Treatment of African Trypanosomiasis
Tacrolimus
ImmunosuppressiveAntineoplastic
Binds FKBP (FK506 binding protein)
Inhibits calcineurin
Tamoxifen
Antineoplastic Antiestrogen
Estrogen receptor anatagonist
Tegaserod
IBS treatment
5HT4 receptor agonist
Telmisartan
Antihypertensive
Angiotensin receptor blocker(ARB)
Temazepam
Sedative/Hypnotic
Benzodiazepine Acts on GABAA receptor
complex
Tenecteplase
Thrombolytic
Tissue plasminogen activator (tPA)
Terazosin
Sympatholytic1 adrenergic antagonist
AntihypertensiveTreatment for benign prostatic
hypertrophy
Terbinafine
Allylamine antifungal
Inhibits ergosterol synthesis by inhibiting squalene epoxidase
Terbutaline
Sympathomimetic2 adrenergic agonist
Short acting bronchodilator Tocolytic
Uterine relaxant
Testosterone
Androgen
Natural male gonadal steroid
Testosterone cypionate
Androgen
Synthetic depot
Testosterone enanthate
Androgen
Synthetic depot
Testosterone propionate
Androgen
Synthetic depot
Tetracaine
Local anaesthetic
Tetracycline
AntibioticBacteriostatic protein synthesis
inhibitor Antiulcer
30S ribosomePrevents aminoacyl tRNA attachment
Thalidomide
AntineoplasticLeprosy treatment
Anti-angiogenicAnti-TNF
Theophylline
Bronchodilator
MethylxanthinePhosphodiesterase inhibitor
Used in asthma
Thiabendazole
Antihelminthic
Treatment of intestinal roundworms
6-Thioguanine
Antineoplastic
Antimetabolite (“pseudofeedback inhibition” of
HGPRT and PRP – purine synthesis)
Thiopental
General Anaesthetic
Ultra-short-acting barbiturate
Thioridazine
Antipsychotic
Phenothiazine
Thiotepa
Antineoplastic
Alkylating agent
Thiothixene
Antipsychotic
Thrombopoietin
Cytokine
Platelet synthesis stimulator
Thromboxane A2 (TXA2)
Autacoid
Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism
Thyrotropin-releasing Hormone (TRH)
Hypothalamic hormone
Stimulates release of thyroid stimulating hormone (TSH) from
the anterior pituitary
ThyrotropinThyroid-stimulating Hormone
(TSH)
Anterior pituitary hormone
Stimulates production of thyroxine (T4), triiodothyronine
(T3) and thyroglobulin
Ticarcillin
Penicillin antibioticCell wall synthesis inhibitor
Anti-pseudomonal penicillinInhibits peptidoglycan cross-
linking
Ticlopidine
Antiplatelet
ADP receptor antagonist
Timolol
Sympatholytic adrenergic antagonist
AntihypertensiveGlaucoma treatment
Anti-anginalBronchoconstrictor
Tissue plasminogen activators
Thrombolytics
alteplase, reteplase, tenecteplase
Tobramycin
Aminoglycoside antibioticBactericidal protein synthesis
inhibitor
30S ribosomeFreezes initiation
Tocainide
Class I antiarrhythmic
Na+ channel blocker(activated channels)
Tolbutamide
Oral hypoglycemic
SulfonylureaInsulinotropic
Tolterodine
Anticholinergic
Muscarinic receptor antagonistPrevents urination
Toremifene
Estrogen antagonist
Selective estrogen receptor modulator (SERM)
Tosemide
Loop diuretic
Na-K-2Cl symporter inhibitor
Trandopril
Antihypertensive
Converting enzyme inhibitor
Tranylcypromine
Antidepressant
Monoamine oxidase inhibitor (MAO-I)
Trastuzumab
Antineoplastic
Anti-HER2 antibody
Triamcinolone
AdrenocorticosteroidGlucocorticoid
Anti-inflammatory steroidInhaled
Triamterene
Potassium sparing diuretic
Sodium channel inhibitorAntihypertensive
Triazolam
Sedative/Hypnotic
Benzodiazepine Acts on GABAA receptor
complex
Trifluoperazine
Antipsychotic
Phenothiazine
Trifluridine
Antiherpes
Pyrimidine analogPhosphorylated to inhibitor of
viral DNA polymerase
Trihexyphenidyl
Antiparkinson
Antimuscarinic
Trimethaphan
SympatholyticAnticholinergic
Nicotinic antagonistAntihypertensive
Trimethoprim
AntibioticProtein and nucleic acid
synthesis inhibitor
Inhibits bacterial dihydrofolate reductase
Tripelennamine
Classical antihistamine
H1 antagonist
Tubocurarine
Paralytic
Paralyzes skeletal muscles
Tumor necrosis factor
CytokineAntineoplastic
Tyramine
Indirect sympathomimetic
VasoconstrictorVasopressor
Ultralente insulin
HormoneInsulin analogue
Long acting
Urokinase
Thrombolytic
Valacyclovir
Antiherpes
Purine analogPhosphorylated to inhibitor of
viral DNA polymerase
Valsartan
Antihypertensive
Angiotensin receptor blocker(ARB)
Valganciclovir
Antiherpes
Purine analogPhosphorylated to inhibitor of
viral DNA polymerase
Valproic acid
Anticonvulsant
Valsartan
Antihypertensive
Angiotensin receptor blocker(ARB)
Vancomycin
AntibioticInhibits cell wall synthesis
Not a lactam
Arginine vasopressin(Antidiuretic hormone;
ADH)
Hypothalamic (posterior pituitary) hormone
AntidiureticVasoconstrictor
Vecuronium
Paralytic
Paralyze skeletal muscles
Verapamil
Class IV antiarrhythmicAntihypertensive
L-type Ca2+ channel blocker Antianginal
Vigabatrin
Anticonvulsant
Irreversible GABA aminotransferase inhibitor
Vinblastine
Antineoplastic
Vinca alkaloidNatural product
Vincristine
Antineoplastic
Vinca alkaloidNatural product
Voriconazole
Triazole antifungal
Inhibits synthesis of ergosterol by inhibiting lanosterol 14
demethylase
Warfarin
Anticoagulant
Vitamin K synthesis inhibitor
Zafirlukast
Leukotriene inhibitor
LTR1 and LTD4 antagonistAsthma treatment
Zalcitabine
Antiretroviral
Nucleoside reverse transcriptase inhibitor (NRTI)
Dideoxycytidine (ddC)
Zanamivir
Antiviral
Inhibits neuraminidaseand decreases viral release
Treatment of Influenza A & B
Zidovudine
Antiretroviral
Nucleoside reverse transcriptase inhibitor (NRTI)
Azidothymidine (AZT)
Zileuton
Leukotriene inhibitor
5-lipoxygenase inhibitorUsed in asthma
Zolpidem
Sedative/Hypnotic
Non-benzodiazepine