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WORLD COUNCIL ON ISOTOPES 1
2019 KOICA-IAEA Joint Training Program
Prepared by the WCI Secretariat
The 2019 KOICA-IAEA Joint Training Program on the
establishment of a long term management plan by
strengthening capacity for diagnostic and
therapeutic radioisotopes and
radiopharmaceutical applications was
implemented by the KAERI in cooperation with the
WCI from September 23 to October 4, 2019.
The opening ceremony took place on 24
September (Tuesday) at the KAERI, Daejeon, Korea.
This training program was organized by the
International Atomic Energy Agency (IAEA) and
the Korea International Cooperation Agency
(KOICA), and implemented by the KAERI in
cooperation with the WCI. It was held over two
weeks. The program consisted of several lectures
and discussion sessions. There were also the
practical exercise sessions together with scientific
visits to hospitals.
From around the world there were a total of 10
experts attending the training course. They were
from Argentina, Bangladesh, India, Macedonia,
Malaysia, Mexico, Montenegro, Philippines, Serbia
01. Lead Article
2019 November Vol.8 – Issue 11
01 Lead Article 1
02 Isotope-related News 10
03 Sketches from the Secretariat 15
04Future Conferences and Events 16
Nigel R. Stevenson President
Van Zyl de Villiers Immediate-Past President
Jong Kyung Kim President-Elect
Bernard Ponsard Chair, Industrial Application
Timothy Payne Chair, Environmental Applications
Tatsuo Ido Chair, Medical Applications
Carlo R. Chemaly Chair, Publication
MeeraVenkatesh Chair, Education and Training
Myung Jae Song Chair, Info. Exchange & Coop.
Paul Dickman Chair, ICI Coordination
Ira GoldmanChair, Long-Term Funding
Woo-Geun Song Director of Secretariat
WCI Secretariat
18F Seoul Forest IT Valley 77 Seongsuil-ro,
Seongdong-gu, Seoul, Korea
TEL: +82-2-3490-7141
Email: [email protected]
www.wci-ici.org
WORLD COUNCIL ON ISOTOPES 2
and Thailand.
For these 10 participants, living expenses and round-trip air tickets were borne by the
Korea International Cooperation Agency(KOICA) of the Republic of Korea. Upcoming
training courses will run through to 2021, over three years starting this year, 2019.
Opening Speech
Dr. Shin Ae Kim, Director of the Nuclear Training and Education Center, the KAERI gave the
opening speech. She said that she was very happy to have an opportunity to host this
training course at the KAERI. She emphasized the importance of nuclear medicine when
addressing prevention, diagnosis, and therapy for human health. She added that the
number of radioisotopes and radiopharmaceuticals is growing rapidly, thereby allowing
the medical community better access to detailed information on diagnostic and
therapeutic applications. Finally, she said that she hoped this training course would
provide the participants with a valuable opportunity to enhance their knowledge and to
share information and their experiences in various countries they come from.
WORLD COUNCIL ON ISOTOPES 3
Congratulatory Speech
Dr. Joao Alberto OSSO JUNIO, Head of Radioisotope Products and Radiation Technology
Section, Division of Physical and Chemical Sciences, IAEA said that the IAEA had
organizing this first training course with the KOICA, the KAERI and the WCI, which had
cooperated effectively over a long period of time. He said that he was happy to have the
opportunity for the KAERI to host this training course in cooperation with the WCI. He said
the training program is going to help member states consolidate the production of
medical isotopes and radio pharmaceuticals. He said participants were going to visit
installations in the country and conduct practical experiments. He strongly encouraged
every participant to discuss, interact and create new networks through active
participation in this training course with a view of developing their future activities. He said
establishing the network among participants was very important. He said it is why the IAEA
supports the program, not only the learning. In addition, he added the IAEA will continue
to support this training program into the future.
Welcoming Speech
Dr. Nigel Stevenson, President of the WCI delivered his welcoming remarks and
emphasized the importance of this training course that seems to be instructive and
stimulating to the participants. He said that all of the participants would have a special
opportunity to learn from the experts and from other specialists. He also wished that this
training program would inject new energy into participants’ work and careers. He also
hoped it would encourage the participants to make the maximum use of their opportunity
in order to gain a new or broader perspective, to share knowledge and experience with
other participants, and to be open to the views of others. Finally, he made a request for
every participant to transfer information from this training program to others in the
participants’ working environments.
WORLD COUNCIL ON ISOTOPES 4
Lectures and Scientific Visits
This training program consisted of lectures and discussion sessions and practical exercise
sessions and scientific visits. The lecture and discussion sessions centered around
radioisotopes (RI) and radiopharmaceuticals(RPs) with regard to policy and regulatory
aspects, and RI and RPs in the technical area. Accordingly, for this session, the 18 lectures
were given by domestic and international experts.
Their lectures were on a variety of topics, including basic radiochemistry and analytical
techniques, the production of RI based on the reactor and the cyclotron, chemistry and
radiochemistry of metallic and nonmetallic RIs, GMP of RPs, quality control of
radiopharmaceuticals, quality control of RPs, preclinical evaluation of RPs, clinical trials
with RPs, compounding and the manufacturing of diagnostic and therapeutic RPs,
regulatory agencies and the regulatory process for RPs, GMP requirements, compounding
and the manufacturing of diagnostic RPs, RP regulatory landscape in the European Union
and in the USA, and guidance for countries for setting optimum RP regulations.
The practical exercise session dealt with reactor and cyclotron facilities including
cyclotron, hot cell, High-flux Advanced Neutron Application Reactor(HANARO),
radioisotope production facility(RIPF), etc., at the KAERI and RP production facilities with
GMP accreditation for therapeutic RPs at the Samyoung Unitech Co., LTD.
In addition, the scientific visits to the hospitals that are involved in RI and RP use for
diagnostic and therapeutic application are at Seoul National Hospital and at Asan
Medical Center in Seoul, Korea.
Country Report Presentation
The participants were given the opportunity to present their country reports that discussed
their current status and other issues, with regard to human resources, the services/business
area, facilities and the utilization of RI and RPs, authentication and regulation, among
WORLD COUNCIL ON ISOTOPES 5
others. It was suggested that their improvement strategies including specific action plans
should be presented in alphabetical order.
Action Plan Formulation and Presentation
To develop the action plan, common sense and assumptions were suggested in the
training course, based on the country reports presented by the participants as follows;
1. The participating country has to have very good infrastructure for SPEC and PET
radiopharmaceuticals preparation, enough human resources for PET and SPECT
radiopharmaceuticals and needs to prepare for GMP and MA(marketing
authorization) or new drug approval for various kinds of PET radiopharmaceuticals.
2. The participant has strong interests in new radioisotope production with cyclotron
or reactors, and considers the importance of the hardware for GMP, etc.
Under the situation with the afore mentioned common sense and assumptions, the
participants were given the following action options for an action plan to develop as
follows;
1. Action 1: The participants need to prepare to do research, complete a project
plan or a fellowship program for radioisotope production or radiopharmaceutical
development.
2. Action 2: The participants should set up and validate GMP regulations for each
country.
3. Action 3: The participants should summarize MA(marketing authorization) or
NDA(New Drug Approval) regulations in each country together with the
reimbursement status.
Considering the above mentioned common sense, assumptions and action options, the
participants prepared action plans for a presentation on the following contents;
1. Background and Purpose
2. Current Status and Issues(Overall, S.W.O.T. analysis, Gap analysis)
WORLD COUNCIL ON ISOTOPES 6
3. Improvement Strategy
4. Specific Action Plan(Overall, the steps to achieve your goals)
5. The steps to achieve your goals(implementing organization, during of the project)
6. Action Plan Timetable
7. Outline of the Action Plan-Budget(if necessary)
8. Expected Results-Outputs/Outcomes)
9. Challenges and Solutions
The participants prepared for their action plans, based on one of their action options
given, and gave their presentations in alphabetical order and discussed with the
participants and consultants to explore the best solution.
Closing Speech
Mr. Woo-Geun Song, the WCI Secretariat Director said that he was very pleased to have
an opportunity to deliver the closing remarks on behalf of the organizers for this training
course. He emphasized the importance of the participant's role. They need to share their
experience with other people all over the world who are working in this field, and asked
the participants to contribute to the promotion of safe and environmentally sound isotope
technologies for global wellbeing. In addition, he expressed his deep appreciation to
KOICA for providing financial support and to the KAERI and the IAEA for preparing this
course in his closing remarks. Especially, he expressed his special thanks to Dr. Hyeon-
Jin(James) Kim and his colleagues for their devoted efforts to have organized this training
course successfully.
Opinions from Participants:
Ms. Ana Clarisa Lopez Bularte from Argentina : She noted that the
program was very well organized and that experts were well
qualified and were showing a high level of professionalism and
enthusiasm for consultations during and after training. She said
friendly ties were created between the different participants and
WORLD COUNCIL ON ISOTOPES 7
that each other’s work experiences helped in finding solutions. She expressed that she was
very grateful for the willingness to seek solutions from both experts and other course
participants.
Ms. Syedzadi Mahbuba Monzur Mouna from Bangladesh : She said
it was a nice concept to make the radioisotope and
radiopharmaceutical sector more effective and more powerful.
She expressed her thanks to KOICA for giving participants a great
opportunity.
Ms. RakheeVatsa from India : This program provided a chance to
build long term friendships with people from 10 different countries.
Not only was there the opportunity to share her culture and field
experiences with other participants, she said there was also the
chance to learn about their cultures away from the scientific work
as well. Also, she added the scientific visits to hospitals, the KAERI
and the traditional Korean Village would be the moments that she would always cherish.
She expressed here gratitude to KOICA and IAEA for giving her this opportunity.
Ms. Katerina Kolevska from Macedonia : She said that she was
thankful to the organizers for giving her the opportunity to
participate in this training program at the highest level. She noted
that it had been a great experience in terms of strengthening
knowledge in the field of radio pharmacy, providing key updates
on new trends in radiopharmaceutical research. She suggested
that the information which was obtained during the lectures and the visits to the
radiopharmaceutical research and production facilities was very useful. She said that it
WORLD COUNCIL ON ISOTOPES 8
had been a pleasure to make many new contacts and to share ideas with the other
participants.
Mr. MohdFirdaus Bin Abdul Aziz from Malaysia : He pointed out that
it was a really good course and an enjoyable few weeks, adding
that trainers and speakers were excellent. On a personal level, he
liked the fact that the time management was excellent and that
sessions and days were not too long, adding that hospitality was
really outstanding.
Ms. Gabriela Contreras Castanon from Mexico : She said that she
was happy and satisfied with the program, because this training
program was confirmed by polite expert scientists. She said that
they were always in a good mood to answer every question.
Adding that, the practice sessions and the field trips were helpful to
understand how the GMP works.
Mr. Sasa LOZO from Montenegro : He said that he had just words of
praise for the perfect organization of this course. He expressed his
gratitude for all beautiful things he had experienced. With the
professional knowledge axis, he said he had the opportunity to
discover Korean culture and delicious cuisine.
WORLD COUNCIL ON ISOTOPES 9
Ms. Joanna Michelle Encarnacion Chua from Philippines : The
KOICA-IAEA joint program was able to cover all topics necessary to
operate a radio pharmacy. She said it was very helpful for those
who have never had formal training in the field. She expressed her
gratitude to KOICA for selecting her as one of the participants for
this 3-year project.
Mr. Marko Peric from Serbia : He expressed that nice surroundings
and magnificent people made the stay in Korea wonderful while
pointing out that the organization of training course was perfect.
Ms. NatphimolBoonkawin from Thailand : She said the training
course was very useful and helpful for the understanding of
radiopharmaceuticals, radiochemistry and quality control, adding
that EP and USP regulation lectures were very useful. They provided
insight with regard to the applying of each country’s regulations,
including the GMP set-up. She expressed her happiness with Korean
culture, cuisine and also the good relationships established or
maintained with all participants.
To Contents
WORLD COUNCIL ON ISOTOPES 10
02. Isotope-related News
8 AI Diagnostics and imaging startups for digital health
Investing in emerging technologies can be extremely risky. It can also be extremely
rewarding - and not just for your bank account. Technologies like artificial intelligence
have the potential to change the world in many different ways. One of the industries
where AI is already making real advances is healthcare, such as the ability to design and
validate drug candidates to treat disease in less than two months.
To read more please visit:
https://www.nanalyze.com/2019/10/ai-diagnostics-imaging-startups/
Source: Nanalyze
Canadian technology offers Fukushima tritium option
Laker TRF Ltd says its water detritiation technology could provide "cost-effective and
reliable" detritiation for light water applications, such as contaminated water at the
Fukushima Daiichi nuclear power plant, and fusion power reactors, such as ITER. The
Canadian company's Advanced Water Distillation (AWD) technology was initially
developed for pressurised heavy water reactors.
To read more please visit:
http://www.world-nuclear-news.org/Articles/Canadian-technology-offers-Fukushima-
tritium-optio?feed=feed
Source: World nuclear news
WORLD COUNCIL ON ISOTOPES 11
Record breaking fusion reaction could transform medical isotope production
Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved
a new world record for a nuclear fusion reaction in a steady-state system, the strongest of
its kind ever produced on Earth. The reaction yielded 46 trillion (4.6×1013) neutrons per
second, eclipsing the previous record by nearly 25% and setting a new standard for
neutron generator technology.
To read more please visit:
https://physicsworld.com/a/record-breaking-fusion-reaction-could-transform-medical-
isotope-production/
Source: Physicsworld
Advanced accelerator applications: innovating against cancer
Cancer is very complex. It is not just one disease. There are hundreds of different types of
cancer, each one with unique characteristics. To make things more complicated, each
person’s disease acts differently.
One of the most challenging things about treating cancer is that it is not predictable and
can change. One therapy may work for a period of time, then stop working. Tumors can
also spread to different parts of the body, making the disease more difficult to treat.
To read more please visit:
https://www.thebusinessdebate.com/advanced-accelerator-applications-innovating-
against-cancer/
Source: The business debate
WORLD COUNCIL ON ISOTOPES 12
US regulator accepts SHINE's radioisotope operating license application
The US Nuclear Regulatory Commission (NRC) has accepted SHINE Medical Technologies'
operating licence application for its medical isotope production facility in Janesville,
Wisconsin. SHINE said the NRC's acceptance confirms that its application was "complete
and of sufficient quality" for the NRC to start its detailed technical review of the
application.
To read more please visit:
https://www.world-nuclear-news.org/Articles/US-regulator-accepts-SHINEs-radioisotope-
operating?feed=feed
Source: World nuclear news
International collaboration secures radioisotope supplies
Research reactors in Canada and the Netherlands will work together to create a dual
supply of the medical isotope iodine-125 (I-125), McMaster University and NRG have
announced. The collaboration is a response to a worldwide shortage of the product in
2017.
Iodine-125 has a half-life of 60 days and is used in brachytherapy for prostate and brain
cancers, as well as in diagnostics and radioimmunoassays.
To read more please visit:
https://www.world-nuclear-news.org/Articles/International-collaboration-secures-
radioisotope-s?feed=feed
Source: World nuclear news
WORLD COUNCIL ON ISOTOPES 13
IAEA Partners with Prominent US Research Hospital to Tackle Childhood
Cancers in Developing Countries
The International Atomic Energy Agency (IAEA) and St. Jude Children’s Research Hospital
are joining forces to combat childhood cancers in developing countries, where children
are four times more likely to die of the disease than in high-income countries due to a lack
of affordable treatment and quality care options.
To read more please visit:
https://www.iaea.org/newscenter/pressreleases/iaea-partners-with-prominent-us-
research-hospital-to-tackle-childhood-cancers-in-developing-countries
Source: IAEA
Illawarra patients await diagnostic scans as Lucas Heights' shutdown
continues
Some Illawarra residents are facing delays for vital diagnostic scans due to a continuing
nationwide shortage of nuclear medicine.
Australia's only nuclear reactor, at Lucas Heights, halted production of the radioisotope
known as molybdenum-99 (Mo-99) after a mechanical fault at the facility on September 6.
Mo-99 is used in 85 per cent of nuclear medicine scans to diagnose cancer, heart disease
and other abnormalities. It's also needed to produce Technetium-99m, a radioactive
tracer which is injected in patients to diagnose a variety of health conditions including
heart, lung, organ and muscular-skeletal conditions.
To read more please visit:
https://www.illawarramercury.com.au/story/6431297/illawarra-patients-face-delays-for-
vital-scans-due-to-nuclear-medicine-shortage/
Source: Illawarramercury
WORLD COUNCIL ON ISOTOPES 14
Inside the ASNC SPECT Imaging Guidelines
The field of nuclear cardiology has expanded greatly over the last few years, prompting
an update of the ASNC SPECT Myocardial Perfusion Guidelines.
Updated guidelines were published in May 2018 and include newer generation cameras,
processing techniques, and key topics such as radiation reduction. These guidelines have
also been endorsed by SNMMI. A core tenet of the guidelines is giving clinicians a review
of the available imaging tools in nuclear myocardial perfusion imaging and focusing
attention on choosing the right test for the right patient at the right time.
To read more please visit:
https://www.digirad.com/asnc-spect-imaging-guidelines/
Source: Digirad
To Contents
WORLD COUNCIL ON ISOTOPES 15
03. Sketches from the Secretariat
[WCI President's Awards/ICI Awards] Call for nominations
The World Council on Isotopes(WCI) has the honor to announce that it would like to invite
all WCI members to nominate any individual, organization or company that has directly
and exceptionally contributed to advancing the WCI’s mission, objectives and activities,
according to Article B7 of the WCI Bylaws.
The categories of the Awards are shown as follows;
1. The WCI President’s Award recognizes (1) outstanding contributions to the
promotion of isotope technologies and the use of isotopes to benefit mankind, or (2)
exceptional contributions to the activities of the Council through, for example,
sharing and the dissemination of relevant information, active cooperation in
promoting the peaceful applications of isotope technologies, provision of
technical/policy advice or training, and technology transfer. The number of the
WCI President’s Award will be restricted to 6 Awards.
2. The ICI Chair’s Award recognizes exceptional contributions to the successful
organization of the International Conference on Isotopes (ICI). The number of the
ICI Chair’s Awards will be restricted to 2 Awards.
The nomination form should be sent to the Director of the WCI Secretariat, Mr. Woo-Geun
Song, by November 20, 2019. Please find the Nomination Form at the WCI
wesite(http://wci-ici.org/06_commu/commu01.html?Item=free&mode=view&s_t=1&No=191)
(including a copy of the relevant Bylaw)for the two awards.
We hope you share our commitment, interest and enthusiasm to award different
stakeholders working in our isotope community.
To Contents
WORLD COUNCIL ON ISOTOPES 16
04.Future Conferences and Events
ASNT Annual Conference 2019
• Date: November 18-21, 2019
• Venue: Las Vegas, America
•Website:
https://www.asnt.org/MajorSiteSections/Events/Upcoming_Events/Annual_2019.aspx
The ASNT Annual Conference will provide a forum for the exchange of theoretical,
scientific and application information. In this challenging economy you need to stay
informed and up to date on the latest advances in NDT technology. Participating in this
conference will expand your knowledge while increasing your visibility.
2020 SNMMI Mid-Winter & ACNM Annual Meeting
• Date: , January 23-25, 2020
• Venue:Tampa, Florida, America
•Website: http://www.snmmi.org/mwm2020
Attention young professionals including those in training (residents, physicians, nuclear
pharmacists, or scientists) or in practice within 10 years of graduation:
Submit your original clinical or scientific abstract for the 2020 ACNM Annual Meeting,
January 23-25, 2020 in Tampa, Florida.
Clinical and scientific abstracts will be accepted on the following topics:
- Aspects of Clinical and Basic Science in Nuclear Medicine/Correlative Imaging in
Nuclear Medicine and Radiology/Nuclear Pharmacy and Physics/ Nuclear
Cardiology/Radionuclide Therapy/Quality and Safety in Nuclear Medicine
WORLD COUNCIL ON ISOTOPES 17
EANM Focus 3 MOLECULAR IMAGING AND THERANOSTICS IN NEUROENDOCRINE TUMOURS
• Date: January 30 - February 1, 2020
• Venue: Athens, GreeceEANM Focus 3 MOLECULAR IMAGING AND THERANOSTICS IN
NEUROENDOCRINE TUMOURS
• Website: https://focusmeeting.eanm.org/
The European Association of Nuclear Medicine (EANM), the world-leading society for
nuclear medicine, molecular imaging and theranostics, is pleased to announce the third
edition of the EANM Focus Meeting – an annual conference in a new format that will take
place in the first months of each year. It will supplement the very successful EANM Annual
Congress in October and the educational events organized by EANM/ESMIT. As all good
things come in threes, it is our special pleasure to inform you that the third EANM Focus
Meeting will be on “Molecular Imaging and Theranostics in Neuroendocrine Tumours”.
10th International Conference on Isotopes
•Date: February 3-7, 2020
•Venue: Kuala Lumpur, MALAYSIA
•Website: https://10ici.org
The theme for 10ICI is “Harnessing Isotopes for Improved Quality of Life” with the main
objective of providing a platform to discuss the state-of-the art developments in isotope
technology for the advancement and application of isotopes in various fields such as
medicine, the environment, industry and agriculture. The conference aims to bring
together scientists, engineers, nuclear and medical physicists, health physicists, radio
chemists, physicians, national and international leaders from business, industry, and
governments to educate, engage, network and exchange best practices with experts
and peers from all parts of the world and to share cutting-edge research and advanced
WORLD COUNCIL ON ISOTOPES 18
state-of-art practice.
20th World Conference on Non-Destructive Testing (WCNDT 2020)
• Date: June 8-12, 2020
• Venue: Seoul, KOREA
•Website: http://www.wcndt2020.com
The 20th World Conference on Non-Destructive Testing (WCNDT 2020) hosted by the
Korean Society for Nondestructive Testing (KSNT) will be held in Seoul, South Korea in June
2020 in association with ICNDT.
To Contents
WORLD COUNCIL ON ISOTOPES 19
WORLD COUNCIL ON ISOTOPES 20
Call for New Members
Becoming a member of WCI – as an organization or as an individual – comes with many benefits.
WCI is the major network concerned with isotopes and isotope technologies in the world.
Take a look on this overview of what WCI Membership can offer you!
Representation
Through consultation and discussion with its members, WCI has knowledge of the
industry, allowing it to carry out an efficient representative role.
Specialized information
The various expert committees of WCI provide members with regular updates
and advice on key industry topics, market developments and relevant legislation.
Training
WCI offers radioisotope-related training programs and provides selected
member trainees with tuition fees, travel expenses, and accommodation.
Newsletter
WCI members receive key information via the WCI monthly newsletter.
Networking opportunities
WCI provides a platform where members benefit from unrivalled networking
opportunities within the industry.
Promotion
WCI’s communication tools, newsletter and website, provide an opportunity for
members to enhance their organization’s profile.
Discounts
Members also enjoy reduced registration rates for the WCI and other specific
events.
Our membership is free and you can apply for WCI membership by eitherour website orby
email.
•on our website: Click here to sign up!
•by e-mail: You can email the WCI secretary by filling out the forms below.
Organization / Individual
For more information please contact [email protected].