Gen. Pharmac. Vol. 22, No. 2, pp. i-xv, 1991 Pergamon Press plc. Printed in Great Britain NEW PATENTS This Section contains abstracts and, where appropriate, illustrations of recently issued United States patents and published patent applications filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the Pergamon PATSEARCH ~ online database in accordance with interest profiles developed by the Editors. Further information about Pergamon PATSEARCH" can be obtained from Pergamon Orbit InfoLine Inc., 8000 Westpark Drive, McLean, Virginia 22102, U,S.A. Copies of complete patents announced in this Section are available from Pergamon Orbit InfoLine Inc. for $8 per copy. Payment with order is required. Orders outside North America add $2 for air postage. Order by patent number for Pergamon Orbit InfoLine only. 4944945 PHARMACEUTICAL COMPOSITION FOR INHIBITING VIRUSES AND INCREASING IMMUNE FUNCTION (PII) Yaguang Lui A safe pharmaceutical composition for treatment and prevention of infections caused by viruses and increasing immune function. The pharmaceutical composition is composed of four active ingredients: Polysaccharides of Wang Qi, Banlankensu, Yejuhua-flavonoid and Guan- zhongsu and method of making the same. 4944946 PHARMACEUTICAL COMPOSITION FOR INHIBITING VIRUSES AND INCREASING IMMUNE FUNCTION (PII) Yaguang Liu A safe pharmaceutical composition for treatment and prevention of infections caused by viruses and increasing immune function. The pharmaceutical composition is composed of four active ingredients: Polysaccharides of Wang Qi, Banlankensu, Yejuhua-flavonoid and Guan- zhongsu and method of making the same. 4944949 PHARMACEUTICAL DELIVERY SYSTEMS Michael J Story, Michael J Flynn, Threapwood, United Kingdom assigned to T I L Medical Ltd Non-steroidal anti-inflammatory drugs (NSAIDs) including diclofenac, flufenamic acid, flurbiprofen, ibuprofen, indomethacin, ketoprofen, naproxen, phenylbutazone, pirox- icam and sulindac are administered in micelles to alleviate their adverse effects on the gastroin- testinal tract. The drugs are formulated with sur- factants such as polyethoxylated nonionics to give micelle-forming compositions. 4945093 NOVEL DERIVATIVES OF UREYLENE, 2,4 TRIAMINOPYRIMIDINE-3- OXIDE, THEIR PREPARATION AND USE IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS Jean Maignan, Serge Restle, Gerard Lang, Tremblay les Gonesse, France assigned to L'Oreal A compound having formula: See Patent for Chemical Structure (I) is described, where R3 and R4 may be identical or different and represent a hydrogen atom, alkyl, alkenyl, cycloalkyl; or R3 and R4 represent aryl aralkyl; or R3 and R4 together with the nitrogen atom linked thereto form a heterocycle; RI and/or R2, inde- pendent of each other, represent hydrogen or carbanoyl having formula: See Patent for Chem- ical Structure (III) where R7 represents alkyl, alkenyl, cycloalkyl, aryl or aralkyl. The com- pounds of formula (I) can be used in cosmetic or pharmaceutical compositions for the cosmetic treatment of hair, the treatment of alopecia, and also for the treatment of desquamating der- matitis.

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Page 1: 4944949 Pharmaceutical delivery systems

Gen. Pharmac. Vol. 22, No. 2, pp. i-xv, 1991 Pergamon Press plc. Printed in Great Britain

NEW PATENTS

This Section contains abstracts and, where appropriate, illustrations of recently issued United States patents and published patent applications filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the Pergamon PATSEARCH ~ online database in accordance with interest profiles developed by the Editors. Further information about Pergamon PATSEARCH" can be obtained from Pergamon Orbit InfoLine Inc., 8000 Westpark Drive, McLean, Virginia 22102, U,S.A.

Copies of complete patents announced in this Section are available from Pergamon Orbit InfoLine Inc. for $8 per copy. Payment with order is required. Orders outside North America add $2 for air postage. Order by patent number for Pergamon Orbit InfoLine only.

4944945

PHARMACEUTICAL COMPOSITION FOR INHIBITING

VIRUSES AND INCREASING IMMUNE FUNCTION (PII)

Yaguang Lui

A safe pharmaceutical composition for treatment and prevention of infections caused by viruses and increasing immune function. The pharmaceutical composition is composed of four active ingredients: Polysaccharides of Wang Qi, Banlankensu, Yejuhua-flavonoid and Guan- zhongsu and method of making the same.

4944946

PHARMACEUTICAL COMPOSITION FOR INHIBITING

VIRUSES AND INCREASING IMMUNE FUNCTION (PII)

Yaguang Liu

4944949

PHARMACEUTICAL DELIVERY SYSTEMS

Michael J Story, Michael J Flynn, Threapwood, United Kingdom assigned to T I L Medical Ltd

Non-steroidal anti-inflammatory drugs (NSAIDs) including diclofenac, flufenamic acid, flurbiprofen, ibuprofen, indomethacin, ketoprofen, naproxen, phenylbutazone, pirox- icam and sulindac are administered in micelles to alleviate their adverse effects on the gastroin- testinal tract. The drugs are formulated with sur- factants such as polyethoxylated nonionics to give micelle-forming compositions.

4945093

NOVEL DERIVATIVES OF UREYLENE, 2,4

TRIAMINOPYRIMIDINE-3- OXIDE, THEIR PREPARATION AND USE IN COSMETIC AND

PHARMACEUTICAL COMPOSITIONS

Jean Maignan, Serge Restle, Gerard Lang, Tremblay les Gonesse, France assigned to L'Oreal

A compound having formula: See Patent for Chemical Structure (I) is described, where R3 and R4 may be identical or different and represent a hydrogen atom, alkyl, alkenyl, cycloalkyl; or R3 and R4 represent aryl aralkyl; or R3 and R4 together with the nitrogen atom linked thereto form a heterocycle; RI and/or R2, inde- pendent of each other, represent hydrogen or carbanoyl having formula: See Patent for Chem- ical Structure (III) where R7 represents alkyl, alkenyl, cycloalkyl, aryl or aralkyl. The com- pounds of formula (I) can be used in cosmetic or pharmaceutical compositions for the cosmetic treatment of hair, the treatment of alopecia, and also for the treatment of desquamating der- matitis.