www.usuhs.edu/4dbio3
4D Bio3 Program Capabilities
The 4D Bio³ facility has a wide assortment of commercially
available and custom bioprinters• Laser induced forward transfer,
extrusion, stereo-lithography,
and microvalve techniques
• Multimodal printing
• Ability to match material properties to cell and tissue
type
• Largest multi-tool bioprinter in the world
The 4D Bio³ lab space is equipped with all the necessities and
expertise for eukaryotic cell culture• Differentiation into any
adult cell type with pluripotent
stem cells
• All cell types in tissue model derive from single source
• Human cell lines with normal chromosomal karyotype
• Rhesus macaque pluripotent cell line with normal
chromosol karyotype
• Ability to add immune component without cross-reactivity
The 4D Bio³ is a Uniformed Services University Program with a
7,000 ft² facility that supports a
broad range of research and education activities related to
biotechnology. The facility includes
a biofabrication suite, tissue culture room, bioreactor and
sensor facility, and medical/surgical
simulation room. The laboratories capabilities encompass
precision medicine, biomarker discovery,
drug and vaccine development, medical technology validation,
bio-sensors, environmental and
occupational health, medical simulation, distance/education
learning, and regenerative medicine.
www.usuhs.edu/4dbio3
The 4D Bio³ facility contains rapid proto-typing technology for
bioreactor design and fabrication• Rapid prototyping
• Multi-chamber format for barrier tissue testing
• Custom applications
• Biocompatible materials
• Continuous monitoring of culture conditions
• Oxygen, TEER, flow, and force measurements
• Optical and electrochemical sensing
4D Bio³ utilizes electrospinning equipment, including
traditional electrospinning and novel direct write technology, to
create 3D tissue • Printing nanofibers to form tissue structures
and scaffolds
• Print rate of hundreds of lines per second
• Ability to print synthetic materials (e.g. polyethylene
oxide) or natural materials (i.e. collagen)
Contacts
Kelli Blaize-WiseDirector of Strategic Partnerships
[email protected]
940-859-8547
Linzie Wagner, PMP, CRAProgram Manager
[email protected]
253-682-3809
