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1338 NATURE MEDICINE VOLUME 5 NUMBER 12 DECEMBER 1999 NEWS Poor attendance bankrupts conference Biomedical researchers keen to commer- cialize their discoveries were left stranded last month when the APEC Technomart III conference and trade fair in Australia closed shop after only two of its scheduled six days. APEC economies, including the US, The People’s Republic of China, Chinese Taipei, Russia, Japan, New Zealand and Indonesia, were expected to generate 30,000 visits to 11 conference venues, but fewer than 3,000 people turned up, send- ing the operating company, PacRim Technomart, into liquidation. On day one, the director of Melbourne’s Baker Medical Research Institute, John Funder, told visitors that the Australian government was “scientifically and tech- nologically illiterate” in failing to move fast enough to cash in on the biotech rev- olution. By day two, exhibitors, who had paid up to AUS$30,000 (US$19,000) for their displays, were inclined to agree, and some speakers were addressing audiences of fewer than ten people. On day three, some of Australia’s well-known biomed- ical researchers—including Mark von Itzstein, whose work led to the develop- ment of the influenza drug zanamivir, and Ian Gust, director of R&D for vaccine manufacturer CSL—were flying in to Cross-disciplinary biomedical research at Stanford University will benefit from a $150 million gift by Jim Clark, a former engineering professor at the university who went on to start Netscape, Silicon Graphics and other companies. With 50 faculty, 400 students and a 20,700-m 2 building, the new Clark Center will be a mid-range privately funded biomedical research institute, equal in size to San Diego’s Salk Institute and somewhat larger than the Whitehead Institute at the Massachusetts Institute of Technology. The center aims to foster collaborations between basic, applied and clinical sciences. Stanford has taken a lead on this with its Institute of Biomedical Engineering, which merges traditionally separate disciplines such as engineering and radiology to approach tasks like sim- ulating the physiology of a knee joint, or calculating blood flow patterns to show how the vasculature is affected by shunts. The center’s programs are all based on the premise that it is no longer possible to think about biomedicine without compu- tation. As industry continues to drain off talent from academia faster than it can be replaced, “we’d like to double the num- ber of people at Stanford who want to make biocomputation a key part of their work,” says Russ Altman, who directs a Stanford informatics program. The largest part of the center, “Bio-X,” will be a more diffuse—hence the variable embedded in its name—aggregation of disciplines, according to its biochemist di- rector, Jim Spudich. ‘Neuroinformatics’, for example, with its heavy imaging com- ponent, requires talent from medicine, cognitive psychology, molecular biology, physics and computer science. Unlike Harvard or Berkeley, Stanford has no Charles River or San Francisco Bay separating its main campus from its medical school, but Campus Drive, a main thoroughfare that bisects the campus, has historically separated medicine from academic departments. The Clark building will bridge Stanford’s ‘moat’ both physically and intellectually. “It makes enormous sense to have this building as a unifier,” says Mike Levitt, chair of Structural Biology. “Clark’s initial investment of $150 million will produce value in the billions,” he predicts. Potter Wickware, San Francisco Queensland’s Gold Coast to deliver their papers just as exhibitors were pulling down their stalls. “I’ve never heard of this happening be- fore,” Peter Timms, director of DNA re- search at the Queenland University of Technology center for diagnostic tech- nologies, told Nature Medicine. “It’s a very competitive world and this was an impor- tant thing for us to get right…I hope that it hasn’t done a huge amount of damage [to Australian research].” Last year’s Technomart, held in Chinese Taipei, generated deals worth a total of AUS$275 million in medicine, defence, agriculture and information technology. Some observers blamed the 1999 collapse on the failure of the private sector opera- tors to deliver an affordable event, even propped up by AUS$500,000 in govern- ment funds. For biotech-promoting politicians like Queensland Premier Peter Beattie, who had personally invited delegates during trade missions to Asia and North America, the collapse was a disaster, moving him to plead “let’s not let this one incident cast a cloud over the excellent reputation and work” being done in Australia. Rada Rouse, Brisbane Stanford donation funds transdisciplinary center More than a decade after a US National Academy of Sciences report to the US Congress called for 10 new research cen- ters devoted to aging research, the first and only such center to have come out of the proposal has opened in Novato, California. The Buck Center, an independent research institute that received $5.5 million from the Leonard and Beryl Buck Trust in 1999, is expected house up to 50 laboratories within the next five-ten years. The cen- ter’s president and CEO, Dale E. Bredesen, is recruiting staff to study neurodegenerative diseases associated with the aging process. “Our initial re- search focus will be to find early markers for diseases such as Alzheimer’s Disease and Parkinson’s, based on proteoge- nomics,” says Bredesen. According to Huber Warner of the National Institute of Aging (NIA), which spends $600 million annually on aging research, the Buck Center is the only in- First independent aging research center opens dependent aging research center in the US, although there are around two dozen universities that have departments de- voted specifically to the field. “Unfortunately, until aging research reaches the level of prominence of something like can- cer, it will be hard to get private funding for these kinds of centers,” says Warner. Using a new $6 million gift from the Brown Foundation, the University of Texas Health Science Center at San Antonio is also planning to build a free- standing Center for Longevity and Aging Studies. “Right now cancer research is the queen of science. But as the average pop- ulation grows older...[aging research] is where the money and demand will be,” says Director of Aging Research Arlan Richardson. The number of senior citi- zens in the US is expected to double by the year 2050, making up over 25% of the population. Kristine Novak, New York The Buck Center © 1999 Nature America Inc. • http://medicine.nature.com © 1999 Nature America Inc. • http://medicine.nature.com

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1338 NATURE MEDICINE • VOLUME 5 • NUMBER 12 • DECEMBER 1999

NEWS

Poor attendance bankrupts conferenceBiomedical researchers keen to commer-cialize their discoveries were left strandedlast month when the APEC Technomart IIIconference and trade fair in Australiaclosed shop after only two of its scheduledsix days. APEC economies, including theUS, The People’s Republic of China,Chinese Taipei, Russia, Japan, New Zealandand Indonesia, were expected to generate30,000 visits to 11 conference venues, butfewer than 3,000 people turned up, send-ing the operating company, PacRimTechnomart, into liquidation.

On day one, the director of Melbourne’sBaker Medical Research Institute, JohnFunder, told visitors that the Australiangovernment was “scientifically and tech-nologically illiterate” in failing to movefast enough to cash in on the biotech rev-olution. By day two, exhibitors, who hadpaid up to AUS$30,000 (US$19,000) fortheir displays, were inclined to agree, andsome speakers were addressing audiencesof fewer than ten people. On day three,some of Australia’s well-known biomed-ical researchers—including Mark vonItzstein, whose work led to the develop-ment of the influenza drug zanamivir,and Ian Gust, director of R&D for vaccinemanufacturer CSL—were flying in to

Cross-disciplinary biomedical research atStanford University will benefit from a$150 million gift by Jim Clark, a formerengineering professor at the universitywho went on to start Netscape, SiliconGraphics and other companies. With 50faculty, 400 students and a 20,700-m2

building, the new Clark Center will be amid-range privately funded biomedicalresearch institute, equal in size to SanDiego’s Salk Institute and somewhatlarger than the Whitehead Institute at theMassachusetts Institute of Technology.

The center aims to foster collaborationsbetween basic, applied and clinicalsciences. Stanford has taken a lead on this with its Institute of BiomedicalEngineering, which merges traditionallyseparate disciplines such as engineeringand radiology to approach tasks like sim-ulating the physiology of a knee joint, orcalculating blood flow patterns to showhow the vasculature is affected by shunts.

The center’s programs are all based onthe premise that it is no longer possible tothink about biomedicine without compu-tation. As industry continues to drain offtalent from academia faster than it can bereplaced, “we’d like to double the num-ber of people at Stanford who want tomake biocomputation a key part of theirwork,” says Russ Altman, who directs aStanford informatics program.

The largest part of the center, “Bio-X,”will be a more diffuse—hence the variableembedded in its name—aggregation ofdisciplines, according to its biochemist di-rector, Jim Spudich. ‘Neuroinformatics’,for example, with its heavy imaging com-ponent, requires talent from medicine,cognitive psychology, molecular biology,physics and computer science.

Unlike Harvard or Berkeley, Stanfordhas no Charles River or San FranciscoBay separating its main campus from itsmedical school, but Campus Drive, amain thoroughfare that bisects thecampus, has historically separatedmedicine from academic departments.The Clark building will bridgeStanford’s ‘moat’ both physically andintellectually. “It makes enormoussense to have this building as a unifier,”says Mike Levitt, chair of StructuralBiology. “Clark’s initial investment of$150 million will produce value in thebillions,” he predicts.

Potter Wickware, San Francisco

Queensland’s Gold Coast to deliver theirpapers just as exhibitors were pullingdown their stalls.

“I’ve never heard of this happening be-fore,” Peter Timms, director of DNA re-search at the Queenland University ofTechnology center for diagnostic tech-nologies, told Nature Medicine. “It’s a verycompetitive world and this was an impor-tant thing for us to get right…I hope that ithasn’t done a huge amount of damage [toAustralian research].”

Last year’s Technomart, held in ChineseTaipei, generated deals worth a total ofAUS$275 million in medicine, defence,agriculture and information technology.Some observers blamed the 1999 collapseon the failure of the private sector opera-tors to deliver an affordable event, evenpropped up by AUS$500,000 in govern-ment funds.

For biotech-promoting politicians likeQueensland Premier Peter Beattie, whohad personally invited delegates duringtrade missions to Asia and North America,the collapse was a disaster, moving him toplead “let’s not let this one incident cast acloud over the excellent reputation andwork” being done in Australia.

Rada Rouse, Brisbane

Stanford donation fundstransdisciplinary center

More than a decade after a US NationalAcademy of Sciences report to the USCongress called for 10 new research cen-ters devoted to aging research, the firstand only such center tohave come out of theproposal has opened inNovato, California.

The Buck Center, anindependent researchinstitute that received$5.5 million from theLeonard and Beryl Buck Trust in 1999, isexpected house up to 50 laboratorieswithin the next five-ten years. The cen-ter’s president and CEO, Dale E. Bredesen,is recruiting staff to studyneurodegenerative diseases associatedwith the aging process. “Our initial re-search focus will be to find early markersfor diseases such as Alzheimer’s Diseaseand Parkinson’s, based on proteoge-nomics,” says Bredesen.

According to Huber Warner of theNational Institute of Aging (NIA), whichspends $600 million annually on agingresearch, the Buck Center is the only in-

First independent aging research center opensdependent aging research center in theUS, although there are around two dozenuniversities that have departments de-voted specifically to the field.

“Unfortunately, untilaging research reachesthe level of prominenceof something like can-cer, it will be hard to getprivate funding forthese kinds of centers,”says Warner.

Using a new $6 million gift from theBrown Foundation, the University ofTexas Health Science Center at SanAntonio is also planning to build a free-standing Center for Longevity and AgingStudies. “Right now cancer research is thequeen of science. But as the average pop-ulation grows older...[aging research] iswhere the money and demand will be,”says Director of Aging Research ArlanRichardson. The number of senior citi-zens in the US is expected to double bythe year 2050, making up over 25% of thepopulation.

Kristine Novak, New York

The Buck Center

© 1999 Nature America Inc. • http://medicine.nature.com©

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