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ABSITE statistics: the absolute basics Christian Jones, MD, FACS Department of Surgery Johns Hopkins School of Medicine

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Page 1: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

ABSITE statistics: the absolute basics

Christian Jones, MD, FACSDepartment of Surgery

Johns Hopkins School of Medicine

Page 2: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

statsO mean: typical “average”O median: middle numberO mode: most frequent numberO normal: type of distribution, equal about a

mean, “bell curve”, mean = median = mode

Page 3: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

termsO incidence: interval of timeO prevalence: point in time

Page 4: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

types of studiesO cohort study: prospective, nonrandom

assignment to treatment groupO case-control study: retrospective,

nonrandom

Page 5: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

biasesO selection bias: test groups end up being

different, e.g., volunteers vs. populationO measurement bias: aka system bias, actual

measurement is inaccurate, e.g., recall biasO exposure bias: aka treatment bias,

treatments not applied equally or as originally planned, e.g., dead patients “withdraw”

Page 6: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

test parametersO sensitivity: how well does the test see the

disease?O specificity: how well does the test make sure

it really is the disease?O positive predictive value: if the test says yes,

how certain can you be that it’s right?O negative predictive value: if the test says no,

how certain can you be that it’s right?

Page 7: ABSITE statistics: the absolute basics - Jones Surgeryjonessurgery.com/wp-content/uploads/Jones-C-ABSITE-Statistics-1.1.pdfABSITE statistics: the absolute basics Christian Jones, MD,

copyright, etc.This document is entirely the work of Christian Jones ([email protected]) and is hereby released into the public domain, with no rights reserved.

This is version 1.1, last modified on 28 January 2016 by Christian Jones. Contact the author by email or on Twitter (@jonessurgery) for questions, comments, or concerns.