21
SIEMENS The E.CAM offers extensive cardiac-specific assessment tools that increase clinical quality and accuracy. The result...an unsurpassed level of clinical confidence. Featuring unique clinical solutions... • Profile non-uniform attenuation correction • Efficient comprehensive review displays • Advanced telemedicine and connectivity packages • Cedars gated SPECTquantification • Emory cardiac quantitative 'toolbox' - EF,volumes and mass - Wall motion analysis - Defect extent/reversibility maps - Transient ischemie dilatation ratio - 3D cardiac displays - Coronary artery overlays/image fusion When it comes to clear outcomes, the E.CAM delivers a level of performance second to none. a clear outcome in Siemens Medical Systems, Inc. • North and South America 847.304.7700 • Canada 905.819.8000 • Europe 49.9131.84.6685 • Asia and Pacific Rim 81.3.5423.4066 • E-mail: [email protected] • Web site: http://www.sms.siemens.com/nmg Circle Reader Service No. 181

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Page 1: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

SIEMENS

The E.CAM offers extensive cardiac-specificassessment tools that increase clinical qualityand accuracy. The result...an unsurpassed levelof clinical confidence.

Featuring unique clinical solutions...•Profile non-uniform attenuation correction•Efficient comprehensive review displays•Advanced telemedicine and connectivity packages•Cedars gated SPECTquantification

•Emory cardiac quantitative 'toolbox'- EF,volumes and mass- Wall motion analysis- Defect extent/reversibility maps- Transient ischemie dilatation ratio- 3D cardiac displays- Coronary artery overlays/image fusion

When it comes to clear outcomes, the E.CAMdelivers a level of performance second to none.

a clear outcome in

Siemens Medical Systems, Inc. •North and South America 847.304.7700 •Canada 905.819.8000 •Europe 49.9131.84.6685 •

Asia and Pacific Rim 81.3.5423.4066 •E-mail: [email protected] •Web site: http://www.sms.siemens.com/nmg

Circle Reader Service No. 181

Page 2: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

I» OProfile Attenuation Correction Emory Cardiac Toolbox Cedars Gated SPECTQuantification

I I I

Siemens medicalSolutionsthat help

Page 3: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

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Page 4: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

See your way clear

Decisive information keepsyou on course

Guiding you to optimal interventionfor neuroendocrine tumors•Somatostatin receptor scintigraphy with OctreoScan

detects and localizes primary tumors and metastaticspread often missed by conventional imaging(sensitivity varies 61%-100%, depending ontumor type).'

•Whole-body scanning can more definitively confirmthe extent of disease.

•You are better able to

- stage the patient- determine diagnostic work-up

- avoid unnecessary procedures

- select optimal treatment

- assesssurgical candidates

- evaluate response to treatment

Transient adverse effects including dizziness,fever, flush, headache, hypotension, changesin liver enzymes, joint pain, nausea, sweating,and weakness were observed in less than 1%of 538 patients during clinical trials.

Please see the prescribing information for specialconsiderations regarding patients receiving total

acetate therapy and patients with insulinoma orimpaired renal function.

Theacceptedstandardfor CEP*tumors

An emergingchoice forsmall cell lung cancer

'Castnxntero-pancreaticneuroendocrinetumofs

OCTREOSCAN

Mr.i.sr sec .¡tlj.ici-nl/).«(•/'or hriri sunmwry (>/'/jr<wri/>/n# intorm.ttion.

Page 5: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

"OCTREOSCAN*KitforthePreparationofIndiumIn-IllPentetreotide

BRIEF SUMMARY OF

PRESCRIBING INFORMATION

OctreoScan'isakitlorthepreparationolindiumln-111pentetreotide,adiagnosticradio-pharmaceutical.It isakitconsistingol twocomponents:1) A 10-mLOctreoScanReactionVialwhichcontainsa lyophilizedmixtureol 10ugpentetreotide.2) A 10-mLvialofIndiumln-111ChlorideStenleSolution.Indiumln-111pentetreotideispreparedbycombiningthetwokitcomponents.

INDICATIONSANDUSAGEIndiumln-111pentetreotideisanagentforthesctntkjraphiclocalizationol primaryandmetastaticneuroendocrinetumorsbearingsomatostatinreceptors.

CONTRAINDICATIONSNoneknown

WARNINGSDONOTADMINISTERINTOTALPARENTERALNUTRITION(TPN)ADMIXTURESORINJECTINTOTPNINTRAVENOUSADMINISTRATIONLINES;INTHESESOLUTIONS,ACOMPLEXGLYCOSYLOCTREOTIDECONJUGATEMAYFORM.Thesensitivityofscintigraphywithindiumln-111pentetreotidemaybereducedinpatientsconcurrentlyreceivingtherapeuticdosesofoctreolideacetate.Considerationshouldbegiventotemporarilysuspendingoctreotideacetatetherapybeforetheadministrationofindiumln-111pentetreotideandtomonitoringthepatientforanysignsofwithdrawal.

PRECAUTIONSGeneral

1.Therapywithoctreotideacetatecanproduceseverehypoglycémieinpatientswithinsulinomas.Sincepentetreotideisananalogofoctreotide,anintravenouslineis recommendedinanypatientsuspectedofhavinganinsulinoma.Anintravenoussolutioncontainingglucoseshouldbeadministeredjustbetöreandduringadministrationofindiumln-111pentetreotide.2.Thecontentsofthetwovialssuppliedwiththekitareintendedonlyforuseinthepreparationofindiumln-111pentetreotideandareNOTtobeadministeredseparatelytothepatient.3.Sinceindiumln-111pentetreotideiseliminatedprimarilybyrenalexcretion,useinpatientswithimpairedrenalfunctionshouldbecarefullyconsidered.4 Tohelpreducetheradiationdosetothethyroid,kidneys,bladder,andothertargetorgans,patientsshouldbewellhydratedbeforetheadministrationofindiumln-111pentetreotide.Theyshouldincreasefluidintakeandvoidfrequentlyforonedayafteradministrationofthisdrug.Inaddition,it is recommendedthatpatientsbegivenamildlaxative(e.g.,bisacodylorlactulose)beforeandafteradministrationofindiumln-111pentetreotide(seeDosageandAdministrationsection).5.Indiumln-111pentetreotideshouldbetestedforlabelingyieldofradioactivitypnortoadministration.Theproductmustbeusedwithinsixhoursofpreparation.6.Componentsofthekitarestenleandnonpyrogenic.Tomaintainsterility,it isessentialthatdirectionsarefollowedcarefully.Aseptictechniquemustbeusedduringthepreparationandadministrationofindiumln-111pentetreotide.7.Octreotideacetateandthenaturalsomatostatinhormonemaybeassociatedwithcholelithiasis,presumablybyalteringfatabsorptionandpossiblybydecreasingmotilityofthegallbladder.Asingledoseofindiumln-111pentetreotideisnotexpectedtocausecholelithiasis.8.Aswithanyotherradioactivematerial,appropriateshieldingshouldbeusedtoavoidunnecessaryradiationexposuretothepatient,occupationalworkers,andotherpersons.9.Radiopharmaceulicalsshouldbeusedonlybyphysicianswhoarequalifiedbyspecifictraininginthesafeuseandhandlingofradionuclides.

Carcinoqenesis.Mutagenesis.Impairmentof FertilityStudieshavenotbeenperformedwithindiumln-111pentetreotidetoevaluatecarcinogenicpotentialoreffectsonfertility.Pentetreotidewasevaluatedformutagenicpotentialinaninvitromouselymphomaforwardmutationassayandaninvivomousemicronucleusassay;evidenceofmutagenicitywasnotfound.

PregnancyCategoryCAnimalreproductionstudieshavenotbeenconductedwithindiumln-111pentetreotide.It isnotknownwhetherindiumln-111pentetreotidecancausefetalharmwhenadministeredtoapregnantwomanorcanaffectreproductioncapacity.Therefore,indiumln-111pentetreotideshouldnotbeadministeredtoapregnantwomanunlessthepotentialbenefitjustifiesthepotentialrisktothefetus.

NursingMothersIt isnotknownwhetherthisdrugisexcretedinhumanmilk.Becausemanydrugsareexcretedinhumanmilk,cautionshouldbeexercisedwhenindiumln-111pentetreotideisadministeredtoanursingwoman.

PediatrieuseSafetyandeffectivenessmchildrenhavenotbeenestablished.

ADVERSEREACTIONSThefollowingadverseeffectswereobservedinclinicaltrialsata frequencyoflessthan1%of538patients:dizziness,fever,flush,headache,hypotension,changesinliverenzymes,jointpain,nausea,sweating,andweakness,Theseadverseeffectsweretransient.Alsoinclinicaltrials,therewasonereportedcaseofbradycardiaandonecaseofdecreasedhematocntandhemoglobin.Pentetreotideisderivedfromoctreotidewhichisusedasa therapeuticagenttocontrolsymptomsfromcertaintumors.Theusualdoseforindiumln-111pentetreotideisapproximately5 to20timeslessthanforoctreotideandissubtherapeutic.Thefollowingadversereactionshavebeenassociatedwithoctreotidein3%to10%ofpatients:nausea,injectionsitepain,diarrhea,abdominalpain/discomfort,loosestools,andvomiting.Hypertensionandhyper-andhypoglycemiahavealsobeenreportedwiththeuseofoctreotide.

DOSAGEANDADMINISTRATIONBeforeadministration,apatientshouldbewellhydrated.Afteradministration,thepatientmustbeencouragedtodnnkfluidsliberally.Eliminationofextrafluidintakewillhelpreducetheradiationdosebyflushingoutunbound,labelledpentetreotidebyglomerularfiltration.It isalsorecommendedthatamildlaxative(e.g.,bisacodylorlactulose)begiventothepatientstartingtheeveningbeforetheradioactivedrugisadministered,andcontinuing

for48hours.Amplefluiduptakeisnecessaryduringthisperiodasasupportbothto renaleliminationandthebowel-cleansingprocess.Inapatientwithaninsulinoma,bowel-deansingshouldbeundertakenonlyafterconsultationwithanendocrinologist.Therecommendedintravenousdosetorplanarimagingis 111MBq(3.0mCi)ofindiumln-111pentetreotidepreparedfromanOctreoScankit.TherecommendedintravenousdoseforSPECTimagingis222MBq(6.0mCi)ofindiumln-111pentetreotide.

Thedoseshouldbeconfirmedbyasuitablycalibratedradioactivityionizationchamberimmediatelybeforeadministration.Aswithallintravenouslyadministeredproducts.OctreoScanshouldbeinspectedvisuallylorpaniculatematteranddiscolorationpriortoadministration,wheneversolutionandcontainerpermit.Preparationscontainingpaniculatematterordiscolorationshouldnotbeadministered.Theyshouldbedisposedofinasafemanner,incompliancewithapplicableregulations.Aseptictechniquesandeffectiveshieldingshouldbeemployedinwithdrawingdosesforadministrationtopatients.Waterproofglovesshouldbewornduringtheadministrationprocedure.DonotadministerOctreoScaninTPNsolutionsorthroughthesameintravenousline.

RadiationDoslmelryTheestimatedradiationdoses'totheaverageadult(70kg)fromintravenousadministrationof111MBq(3mCi)and222MBq(6mCi)arepresentedbelow.TheseestimateswerecalculatedbyOakRidgeAssociatedUniversitiesusingthedatapublishedbyKrenning,etal.'

EstimatedAbsorbedRadiationDosesafterIntravenousAdministrationof Indiumln-111Pentetreotide'toa70kgpatient

| PLANARSPECT09»_jHHKidneysLiverSpleenUterusOvariesTestesRed

MarrowUrinary

BladderWaiGl

TractStomach

Wall

SmallIntestineUpper

LargeIntestineLower

LargeIntestineAdrenalsThyroidEffective

Dose'Equivalent54.1612.1573.866.344.892.903.4630425.874.785.807.737.557.43mSv/111MBqrads/3mCi

j mGy/222MBq ;rarJsfômCi5.42Ì227.390.630.490.290.353.04O.S70.48MB0.770.760.74••-

rem/3mCi108.32

24.31147.7312.679.795.806.9160.4811.349.5811.5915.4615.1114.86

mSv/222MBq10.83

2.4314.771.270.980.580.696.051.130.961.161.551.511.49rem/8mCi

a13.03

1.30 26.06 2.61

1.Valueslistedincludeacorrectionforamaximumof0.1%indiumln-114mradiocontaminantatcalibration.2.E.P.Krenning,W.H.Bakker.PPM.Kooij,W.A.P.Breeman,H.Y.Oei,M.deJong,J.C.Reubi,T.J.Visser,C.Bruns,D.J.Kwekkeboom,A.E.M.Reijs,P.M.vanHagen,J.W.Köper,andS.W.J.Lamberts,"SomatostatinReceptorScintigraphywithlndium-111-DTPA-D-Phe-1-OctreotideinMan:Metabolism,DosimetryandComparisonwithlodine-123-Tyr-3-Octreotide,"TheJournalofNuclearMedicine,Vol.33,No.5,May1992.pp.652-658.

3.Assumes4.8hourvoidingintervalandInternationalCommissiononRadiologicalProtection(ICRP)30modelforthegastrointestinaltractcalculations.4.Estimatedaccordingto ICRPPublication53.

i

HOWSUPPLIEDTheOctreoScankit,NDC0019-9050-40,issuppliedwiththefollowingcomponents:1. A10-mLOctreoScanReactionVialwhichcontainsa lyophilizedmixtureof:

(i) 10ugpentetreotide[N-(diethylenetriamine-N,N.N'.N"-tetraaceticacid-N"-acetyl)-D-phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyt-L-lysyl-L-threonyl-L-hemicystyl-L-threoninolcyclic(2-»7)disulfide).(alsoknownasoctreotideDTPA),

(ii) 2.0mggentisicacid [2.5-dihydroxybenzoicacid],(mi4.9mgtrisodiumcitrate,anhydrous,iiv)0.37mgcitricacid,anhydrous,and(v)10.0mginositol.

Beforelyophilizalion,sodiumhydroxideorhydrochloricacidmayhavebeenaddedforpHadjustment.Thevialcontentsaresterileandnonpyrogenic.Nobacteriostaticpreservativeispresent.2.A 10-mLvialofIndiumln-111ChlorideSterileSolution,whichcontains1.1mLof111MBq/mL(3.0mCi/mL)indiumln-111chloridein0.02NHCIattimeofcalibration.Thevialalsocontains'ernechlorideataconcentrationof3.5ug/mL(ferricion.1.2ug/mL).Thevialcontentsaresterileandnonpyrogenic.Nobacteriostaticpreservativeispresent.Inaddition,thekitalsocontainsthefollowingitems:(1)a25Gx5/8"needle(B-DMonoject)usedtotransferIndiumln-111ChlorideSterileSolutiontotheOctreoScanReactionVial.(2)apressuresensitivelabel,and(3)apackageinsert.

IALLINCKRODT

Mallinckrodt Inc.,Mallinckrodt Nuclear Medicine Division

P.O. Box 5840St. Louis, MO 63134

1. Termanini B, Cibril F, Reynolds JC, et al. Value of Somatostatin Receptor Sciniigraphy: A Prospective Studyin Gastrinoma of its Effect on Clinical Management. G.isfroenfero/cgy1997;112:335-337.

©1997MallinckrodtInc. MI22701

Circle Reader Service No. 110

12/97

Page 6: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

Nuclear Medicine Self-Study Programs in Cardiology

Renew Your Perspective on NuclearMedicine Cardiology with the SNM's

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.#Los Angeles: H. William Strauss. Stanford University MedicalCenter, Stanford; and Mario S. Verani, Methodist Hospital,Houston.

4

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Page 7: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

Nuclear Medicine Self-Study Programs in Oncology

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NUCLEAR MEDICINE:

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available.

The all-new Oncology Self-Study series offers eight topic booklets, a new topic booklet published every three months. Eachbooklet includes an extensive list of annotated references, questions and answers with critiques, along with an authoritative syllabus review of the topic. Publication dates are in parenthesis.

Oncology Topic BookletsSeries Editor: Thomas P. Haynie, MDOncology Series Writers: Gerald L. Denardo,MD, Randall Hawkins, MD, PhD, E. EdmundKim, MD, Alexander J. McEwan, MD, Hani A.Nabi, MD, Patrice K. Rehm, MD, Edward B.Silberstein, MD and Richard Wahl, MD

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To order, simply contact SNM's book distributor, Matthews Medical Books, at their toll-freenumber (800) 633-2665 (non-U.S. 314-432-1401), or Fax: (314) 432-7044). If you chooseto order the complete series, please have yourcredit card number ready when callingMatthews Medical Books. Each topic bookletwill be automatically sent to you as they arereleased. Your credit card will only be chargedonce a booklet is ready for shipping.

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Page 10: aclearoutcomein - The Journal of Nuclear Medicinejnm.snmjournals.org/content/40/1/local/advertising.pdf · "OCTREOSCAN* KitforthePreparationofIndiumIn-IllPentetreotide BRIEFSUMMARYOF

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LOCATION:Los Angeles Convention Center1201 South Figueroa StreetLos Angeles, GA 90015

DEADLINES:Pre-Registration Ends:

Last Day for Housing Reservations:Abstract Submission Deadline:

April 29, 1999April 29, 1999January 8, 1999

REGISTRATION FEES:CategoricalSaturday, .June5, 1999 Prc-Registration On-SiteMember 8115 8135Non-Member 8145 8165

(Boxed lunch is provided for the Saturday Categorical only,

the cost of which is included in the fee)

CategoricalsSunday, June 6, 1999MemberNon-Member

Prc-RcgistrationS1008130

On-SiteS120«150

Continuing EducationMonday, June 7, 1999 through Thursday, June 10, 1999

Member Pre-Registration On-SitePhysician/Scientist/Pharmacist S335 S395Technologist S205 8255

Non-MemberPhysician/Scientist/Pharmacist 8530 8590Technologist 8395 8450

Companion S55 S55

EXHIBITS:Monday, June 7, 1999 through Thursday, June 10, 1999Exhibit space is 821.50 per square foot.Contact Jane Day [email protected] for further information.

HOW TO OBTAIN PRE-REGISTRATIONAND HOUSING FORMS:1. The SNM Web Site, www.snm.org. starting January2. Fax-On-I)emand°, starting January

3. The Journal of Nuclear Medicine, February Issue4. The Journal of Nuclear Medicine Technology, March Issue

HOW TO OBTAIN A FREE COPY OFTHE SOFTWARE THAT YOU WILLNEED TO SUBMIT YOUR ABSTRACT:1. DOWNLOAD Submitter Assistant Software for the PC/Macfrom the SNMWeb Site at www.snm.org -or-

2. REQUEST a copy of the Submitter Assistant on diskette fromMedical Support Systems (MSS) at:

Attn: Submitter Assistant RequestSociety of Nuclear Medicine1000 Massachusetts Avenue, 3rd FloorCambridge, MA02138-5394

USA

Phone: (800) 375-2586 (USA), (617) 492-0509 (International)FAX:(800) 830-2586 (USA), (617) 876-5351 (International)E-mail: [email protected]

Please specify PC or Macintosh.

* Fax-on-I)emand is <inautomated system that faxes you thoseportions qf the Annual Meeting Preview you request. Ifyou do notknow exactly which ¡Mirtinayou would like to receive (or what isavailable), you can refluent an index of documents when prompted bythe system.

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WHERE DO YOU FIT IN?

WHAT IS THE UA DATA BASE?The Commission on Health Care Policy andPractice in conjunction with the SNMTechnologist Task Force on Utilization Data, hasdeveloped a quarterly survey on SNM's web

site. Participants enter data quarterly.The website's data entry form will collect infor

mation from nuclear medicine practitioners tocompile a utilization analysis database.

The database contains information on:•Facility type and location

•Active general medicine and surgical beds

•Outpatient encounters (visits)

•Physician, technologist and clerical FTEs

•Planar, SPECT, PET Hybrid gamma cameras

and PET scanners•Inpatient and outpatient procedures for a

selected set of commonly used nuclear medicine CPT-4 codes

WHY SHOULD YOU PARTICIPATE?Participants receive standard reports on utilization by procedure, place of service, type ofpatient, etc.

Participants will be able to compare their facilitydata with others in the region and with thenational (global) averages.

Subscribers may query reports on-line or

receive printed reports quarterly via mail.This is a free service. As long as you input yourdata quarterly, you will be able to obtain dataand reports.

All information is confidential.For more information or to participate in thisprogram, contact UA ^^^^Project Coordinator at •fpT| UTILIZATION(703) 708-9000 x255 or ¡DATABASEe-mail: [email protected]. I b ••ANALYSIS

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AN N O U N CI N G

TheAmericanBoardof

ScienceInNuclear

Medicine1999

CertificationExamination

The1999examinationwillbegivenSunday,June6,1999inLosAngeles,CAinconjunctionwiththe46thAnnualMeetingoftheSocietyofNuclearMedicine.The examination is written and consists of two parts —

Part One (3.5 hours) assesses knowledge of basic aspects of NuclearMedicine Science.

Part Two (2.5 hours) examines in depth the knowledge of apredetermined subspecialty area of the candidate's choice including:

•Nuclear Medicine Physics and Instrumentation

•Nuclear Pharmaceutical Science and Radiochemistry

•Radiation Protection

Completed Applications must be postmarked by March 12,1999.The examination fee is $650 ($550 refundable if you do not qualify).

For applications and more information, please contact:ABSNM Exam CoordinatorAmerican Board of Science in Nuclear Medicinec/o The Society of Nuclear Medicine1850 Samuel Morse Drive, Reston, Virginia 20190-5316Tel: (703) 708-9000, ext. 227 •Fax: (703) 708-9013

1ère

O* WCll .tR h* DK

The new, third edition of the widely popular SPECT: APrimer is now available from Matthews Medical Booksat the toll-free number below.

Substantially updated and expanded throughout, the third editionincludes even more basic information essential to the technologistworking in day-to-day clinical settings.

The new SPECT Primer features an enhanced section on ClinicalApplications, incorporating the latest and most widely acceptedfundamental knowledge in the field, with, three all-new chapters

on Acquisition Devices, Processing Devices, and ClinicalIndications. And in every chapter, you'll find expanded material to

help nuclear medicine professionals who use SPECT perform atpeak.Whether you're a working technologist, teacher, or student, the

new edition of SPECT:A Primer is a must for your clinical library.No other text available brings together—clearly and authoritatively—theessential information you need to understand and useSingle Photon Emission Computerized Tomography.

Call toll-free to order your copy today—$30.00members/$40.00 nonmembers.

Matthews Medical Books •800-633-2665 •(Non-U.S., call 314-432-1401)

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Do you know the most effective and efficient wayto perform a myocardial perfusion study?

How does your procedure for performing renal studies for renovas-cular hypertension compare withthe procedure recommended byleading nuclear medicine experts?

How should you modify yourprocedures for adult patientswhen they are performed inpediatrie patients?

The answers to these questions and more may

be found in the 1997 Society of Nuclear Medicine

Procedure Guidelines Manual. This publication will help

you achieve high quality nuclear medicine studies to insure that your

patients get the treatment they deserve.This informative and useful reference tool

is now available for only $20.00. To order your copy contact Marie Davis at(703)708-9000 x2SO or via email at [email protected]

CONTENTS INCLUDE

PROCEDURE GUIDELINE DEVELOPMENT PROCESS

CARDIAC GUIDELINESGuideline for Myocardial Perfusion ImagingGuideline for Gated Equilibrium RadionuclideVentriculography

ENDOCRINE GUIDELINESGuideline for Thyroid Uptake Measurement

Guideline for Thyroid ScintigraphyGuideline for Extended Scintigraphy for Differentiated

Thyroid Cancer

Guideline for Parathyroid Scintigraphy

GASTROINTESTINAL GUIDELINESGuideline for Hepatobiliary Scintigraphy

Guideline for Hepatic and Splenic ImagingGuideline for C-14 Urea Breath Test

GENERAL GUIDELINESGuidelines for Guideline Development

Guideline for General Imaging

Guideline for Imaging With Radiopharmaceuticals

GENITOURINARY GUIDELINESGuideline for Diagnosis of Renovascular Hypertension

INFECTION GUIDELINESGuideline for Gallium Scintigraphy in InflammationGuideline for In-1 I I Leukocyte Scintigraphy for Suspected

Infection/InflammationGuideline forTc-99m Exametazime (HMPAO) Labeled Leukocyte

Scintigraphy for Suspected Infection/Inflammation

NEUROLOGY GUIDELINESGuideline for Brain Perfusion Single Photon Emission Computed

Tomography (SPECT) Using Tc-99m Radiopharmaceuticals

ONCOLOGY GUIDELINESGuideline for Gallium Scintigraphy in the Evaluation of Malignant

DiseaseGuideline for Tumor Imaging Using F-18 FDG

Guideline for Bone Pain Treatment

PEDIATRIC GUIDELINESGuideline for Pediatrie Sedation in Nuclear Medicine

Guideline for Radionuclide Cystography in Children

Guideline for Diuretic Renography in Children

Guideline for Renal Cortical Scintigraphy in Children

PULMONARY GUIDELINESGuideline for Lung Scintigraphy

SKELETAL GUIDELINESGuideline for Bone Scintigraphy

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APublicationoftheSocietyofNuclearMedicine

DIAGNOSTICPATTERNSINNUCLEARMEDICINE

Authors: Edward B. Silberstein, MDJohn G. McAfee, MDAndrew P. Spasoti

This reference book provides a complete list ofdifferential diagnoses for virtually every patterndescribed in modem nuclear medicinescintigraphy, including the latest findings innuclear cardiology, PET,antibody andsomatostatin receptor imaging. A full list of alldiagnostic patterns reported for every organsystem is given. Pharmacologie effects onlabeling and distribution are fully described.

Diagnostic Patterns in Nuclear Medicine assists inimage interpretation by providing completediagnoses for every scintigraphic pattern. Allentries are documented by published references.Organization by organ system provides an easy-to-fìnd,detailed differential diagnosis.

The clinician simply looks up any scintigraphicfinding to determine possible causes of thatfinding, ranked in order of probability, makingDiagnostic Patterns in Nuclear Medicine the mostcomplete referenced diagnostic guide available.

ISBN: 0-932004-69-5

Price: $45 (members);$63 (nonmembers).

First-pass radionuchde

MTTERNSIN NUCLEAR

1. Superior vena cavaa. obstruction

sawardB-Sibastein

Jthn G. McAfee

Andrew P.

Table of ContentsPart I: CardiovascularSystemPart II: Central Nervous SystemPart III: EndocrineSystemPart IV: The EyePart V: GalliumImagingPart VI: GastrointestinalSystemPart VII: GenitourinarySystemPart VIII: HématologieStudies/DiseasesPart IX: Peri-Diaphragmatic Disease

Part X: PulmonarySystemPart XI: SkeletalSystemPart XII: Tumor/InflammationImaging (Non-Gallium, Non-Leukocyte)

For more information on SNM books, visit our Web site:

http://www.snm.org

To order, simply callMatthews Medical Books at

their toll free number:

800-633-2665Non-U.S. 314-432-1401 or

FAX 314-432-7044

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ights! Camera! Act on yourpassion for nuclear medicine atthe Society of Nuclear Medicine's

46th Annual Meeting.

The latest developments that willkeep you at the forefront ofnuclear medicine await you.Here you will findcomprehensive continuingeducation sessions and refreshercourses on the latest nuclearmedicine issues that willencompass practical and basicaspects of nuclear medicine

procedures in the management ofclinical dilemmas and their cost-

effectiveness. Also included willbe courses pertaining to the state-of-the-art in instrumentation and

radiopharmaceuticals, andupdates on new regulations.These courses will also emphasizethe practical roles of SPECT andPET in a variety of diseaseentities such as myocardialperfusion, brain perfusion, cancerdetection and staging.

The Technologist Section

June 6-10, 1999Join 7,OOO attendees from around the world at theSociety of Nuclear Medicines 46th Annual Meeting

educational program will followthe theme of diseasemanagement.

Continuing education sessionsand categorical seminars offerattendees approximately 33credit hours of AMACategory 1CME for physicians, ACPE forcontinuing pharmaceuticaleducation for pharmacists, andGEH through the VOICE programfor technologists (for coursesoffered Saturday, June 5 throughThursday, June 10, 1999).

Join us !

For further information contact the Department: Meeting Services, 703-708-9000 ext. 229, fax on demand at 888-398-7662 or

visit us at our website www.snm.org

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OF NUCLEAR MEDICINE PATIENT PAMPHLET SERIES

EducateYourPatientsSNMPatient PamphletsOffer the ReassuranceYourPatients Need

Asa clinician,youknownuclear

medicineproceduresaresafe

andeffective.Butyoualsoknow

that patientsaresometimes

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patientspeaceof mindbypro

vidingthemwith conciseand

thoroughinformation.Whateveryour

mostcommonlyorderedprocedure,you'll find anSNMPatientPamphlet

that will addressyour

patient educationneeds.

lucie«RitteimpsfuiOï«nma[Dimettilitati

For more information on SNMbooks, visit our Web site:

http://www.snm.org

Startwith "TheBenefitsof Nuclear

Medicine."Thispamphletdefinescom

monlyperformednuclearmedicinepro

cedures,andincludesaquestionand

answersectiongearedfor the patient.

OtherPatientPamphlettopicsoffer

yourpatientsdescriptionsonspecific

exampreparations,examprocedures

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patientsto follow whentheygohome

andafter their treatment.

•NuclearMedicineBenefits

•RadioiodineTreatment•Stress-RestTest

•BrainImaging

•LiverandHepatobiliaryImaging

•BreastImaging

•BoneImaging

•RenalImagingin Children

•ProstateCancer

•OvarianandColorectalCancer

All pamphletsare40C/copy;

minimumorderof 50.

Toorderthe SNMPatientPamphletSeriescontactthe SNM's 800-633-2665

medicalfulfillment company,MatthewsMedicalBooks. Non-U.S.314-432-1401or FAX314-432-7044E-mail:[email protected]

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Positions NeededPostdoctoral Fellowship in PET/SPECT/f MRIImaging

Unique opportunity for postdoctoral training in functional imaging research. Emphasis on neuropsychiatrie,psycho-pharmacologie, oncology imaging and quantification techniques. Excellent mix of clinical and basicresearch. Opportunity for fMRI/PET correlation. MD/clin-ical credentials required. May start as early as June 1999.Applications to Dean F. Wong. MD. PhD, Johns Hopkins Med Inst. Radiology-JHOC Bldg, Rm. 3245, 601N. Caroline St.. Baltimore. MD 21287-0807. E-mail:drwongferad.jhu.edu.

Faculty Position-Northeast FloridaThe University of Florida Health Science Center/Jacksonville seeks MD, BC/BE in Diagnostic Radiology, withSpecial Competency or BC/BE in Nuclear Medicine.Fringe benefits are excellent, salary is negotiable. This isa full-time faculty position in the Department of Radiology, with academic rank based on training, backgroundand experience. Send CV and references to Chairman,Search Committee. Radiology Department. 655 W. 8thSt., Jacksonville, FL 32209. Fax: (904) 549-3382.EOE/AAE.

BCIM/NMUnique practice opportunity available for expanding two-man group practice for BC IM/NM physician. Practiceresponsibilities include hospital-based and outpatient NM

facilities and private practice of IM with special emphasis on thyroid disease, osteoporosis and diabetes. Qualified applicants send CV to Carolina Nuclear Medicine,841 Heather Rd., Burlington. NC 27215.

Full-Time Nuclear PhysicianFull-time nuclear physician for a community hospitallocated an hour drive from Chicago. Modem departmentwith Picker triple- and dual-head cameras. Would prefera recently trained physician with board certification andinterest in nuclear cardiology. Please send CV to Amar-jit Kochar, MD, Departments of Pathology and NuclearMedicine, St. Mary Medical Center, 1500 S. LakeparkAve., Hobart, IN 46342. Phone: (219) 947-6266. Fax:(219)947-6306.

Nuclear Medicine ServiceDepartment of Veterans Affairs

Medical CenterDallas, TX 75216

Applications are being sought for a full-time Nuclear

Medicine Staff Physician, Veterans Affairs MedicalCenter, Dallas, TX.The position includes an academicappointment in the Department of Radiology,University of Texas Southwest Medical School.

Applications must be board eligible or board certifiedin Nuclear Medicine. Cardiac, Therapeutic and SPECTexperience as well as strong research capabilitiesrequired.

Responsibilities include teaching Radiology andNuclear Medicine residents. A CVand 3 letters of reference should be sent to: Ana Mello, MD, Chief, NuclearMedicine Service, Veterans Affairs Medical Center,4500 Lancaster Rd.,Dallas, TX 75216.

NO TELEPHONE CALLS ACCEPTED.

Equal Opportunity EmployerApplicants Subject to Drug Testing

Smoke-Free Facility

34A THE JOURNALOFNUCLEARMEDICINE•Vol. 40 •No. 1 •January 1999

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CLINICAL VERSATILITY

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