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8/3/2019 Age Defying Process Using Hyaluronic Acid
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AGE DEFYING PROCESS
USINGHYALURONIC ACID
By-
P.Yasaswini
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Intro..
Hyaluronic Acid- Key To The Fountain Of Youth
A natural sugar that gives skin fullness andelasticity that removes wrinkles and acts as amoisturizing agent.
It is found in human connective tissue includescartilage, epithelial tissue, neural tissue, extracellular matrix.. etc.
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In details..
In 1934, Karl Meyer, John Palmer isolated thissubstance from the vitreous body of cows eyes
for the first time.
Hyaluronic Acid is a type ofmucopolysaccharidecalledglycosaminoglycan.
Hyaluronic Acid is composed ofN-Acetyl
glucosamine andglucuronic acid.
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Sources of HA
Animal products is believed to be the bestnatural source available.
Even most hyaluronic acid supplements are
made from rooster combs.
Magnesium is needed in the body to synthesize
hyaluronic acid, so consuming foods rich inmagnesium, like peanuts, potatoes, soy andspinach can keep hyaluronic acid levels fromdropping too low.
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Glucuronic acid
A carboxylic acid that binds toxins togetherand make them more water soluble.
It is formed in the liver, the excessive dose
results in the damage of liver.
USES:
Glucuronic acid is the precursor of ascorbic acid.
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N-acetylglucosamine
A monosaccharide derivative of glucose.
This Polymerizes with glucuronic acid it forms thehyaluronic acid.
This derivative are found in the brains of mammal.
USES:
Helps in immune system functioning.Decrease the pain and inflammation, repaircartilages.
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Dermal fillers..
Dermal fillers reverse of changes that are oftenassociated with old age.
This is used for injection in the dermis for thepurpose of augmenting soft tissues.
So HA can be used as a dermal fillers.
The two most popular filler materials used areHyaluronic Acid and collagen.
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EXAMPLES OF DREMAL FILLERS..
Restylane
Revanesse
Elevess Radiesse
Evolence
Sculptra
Juvederm
Perlane
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Results of dermal fillers..
These fillers are to be taken once in 6 months.
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Effects..
Excessive usage of hyaluronic acid resultsredness, pain, itching, tenderness and swellingat the site of injection.
Vitamin E supplements, aspirin, non steroidalanti-inflammatory drugs (NSAIDs) such asAleve and Motrin may increase bruising orbleeding after injection of hyaluronic acid.
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Research study on HA
HA along with its biocompatibility andimmunogenicity has led to its use in a numberof clinical applications.
Like supplementation of joint fluids inarthritis, surgical aid in eye surgery.
Most recently HA has been investigated as adrug delivery agent for various routes ofadministration including ophthalmic, nasaletc.
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Conclusion..
Fillers are a practical and a temporary solution
to look young without undergoing majorsurgical procedures.
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Acknowledgement
Smt N. K .D. DEVI
K. ANIL KUMAR
K.V.S.R.Siddhartha College OfPharmaceutical Sciences ,Vijayawada
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Thank you