Anatomy for the Gynecologic Oncologist

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    Overview

    Abdominal wall anatomy

    Upper abdomen organs, vessels,

    innervation Pelvic anatomy

    Vulvar anatomy

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    Abdominal wall anatomy

    Best to comprehend the anatomy as it relates to

    incision types Midline, Pfannenstiel, Maylard &

    Cherney

    What dermatomes are affected by a midline

    incision? What are affected by a pfannenstiel?

    Name all the layers of the abdominal wall above

    and below the arcuate line?

    Describe the relationship between the incision

    type and the inferior epigastric artery?

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    Innervation of the abdominal wall

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    Musculature

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    Rectus sheath

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    Rectus sheath

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    Course of the epigastric artery

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    Veins of the abdominal wall

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    Upper abdominal anatomy

    Adequate debulking of ovarian carcinomarequires dissection of several key organs

    What vessels supply the omentum,spleen, stomach, small bowel, colon andliver?

    What are their functions?

    How do you manage these organspostoperatively if they are injured orremoved?

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    Omentum

    Functions as a filter for lymphatic fluid

    Lymph fluid flow in a clock-wise patternsecondary to peristalsis of the ascending,

    transverse and descending colon Brings lymph fluid to the cisterna chyli, the

    thoracic duct and then the left brachiocephalicvein

    Right sided lymphatic drainage is directedthrough lymphatic channels of the diaphragm tothe azygos system and then the IVC and SVC

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    Omentum

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    Stomach

    Second organ involved with digestion

    Innervated by the vagus nerve

    Blood supply from the celiac trunk: left and right

    gastric arteries, right and left gastroepiploicarteries and the short gastric arteries

    Produces hydrochloric acid and pepsin to digestfood

    Produces 1 to 1.5 liters of fluid each day

    Injury can be controlled by primary closure Continuous NG suctioning causes a

    hyponatremic, hypokalemic metabolic alkalosis

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    Stomach

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    Spleen

    Filter for senescent erythrocytes and circulatingpathogens

    Major producer of opsonins (properdin/ tuftsin)

    Hilum contains the splenic artery and vein

    Extremely vascular

    Splenocolic ligament must be mobilized to free thesplenic flexure of the colon

    Posterior aspect of this ligament in close proximity to thetail of the pancreas

    Splenectomies patients are at risk for pneumonia,

    bacteremia, pancreatic injuries and splenic abcesses MUST BE VACCINATED POST OPERATIVELY FOR: Streptococcus pneumoniae

    Haemophilus influenzae

    Nisseria meningitidis

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    Spleen

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    Small Bowel

    On average 270 to 290 cm in length

    Consists of the duodenum ( 20cm), jejunum (100 to110cm) and ileum (150 to 160 cm)

    Entire blood supply from the superior mesenteric artery

    Both parasympathetic and sympathetic innervation Parasympathetic innervation is from the vagus nerve

    which stems from the celiac ganglion

    Parasympathetic innervation controls motility andsecretion of enzymes

    Sympathetic innervation from three sets of splanchnicnerves oriented around the base of the SMA

    Sympathetic innervation responsible for pain sensationand blood vessel motility

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    Small Bowel

    Majority of nutritional uptake is responsible within thejejunum and ileum

    80% to 90% of proteins reabsorbed in the jejunum

    95% of lipid reabsorbed within the jejunum and ileum

    8 to 10 liters of water are reabsorbed, perhaps only 500ml actually enter the cecum

    Fat soluble vitamins are reabsorbed in the terminal ileum(A, D, E and K)

    Vitamin B12 also reabsorbed in the terminal ileum KEY POINT: the more small bowel removed expect

    problems with digestion, nutrition and diarrhea

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    Small Bowel

    Enzymes of the small bowel

    Gastrin (D) promotes gastric acid and pepsinogen

    production

    CCK(D) promotes pancreatic enzyme secretion andgall bladder contraction

    Secretin (D,J) causes water release, secretion of bile

    salts and inhibition of gastrin

    Somatostatin (P) universal off switch Gastrin releasing peptide (D,J,I) universal on switch

    Motilin (D,J) stimulates upper GI motility

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    Small Bowel

    Small Bowel Obstruction

    Adhesions 60%

    Malignancy 20%

    Hernias 10%

    Crohns disease 5%

    Miscellaneous 5%

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    Duodenum

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    Small Bowel

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    Small Bowel

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    Colon

    6 segments cecum and appendix,

    ascending, transverse, descending,

    sigmoid and rectum

    On average 130 to 150 cm in length

    Blood supply from the superior mesenteric

    and inferior mesenteric arteries (SMA &

    IMA)

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    Segments of the colon

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    Blood supply to the colon

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    Colonic function

    Absorption

    1000 to 1500ml of ileal effluent crosses the ileocecal

    valve

    Stool has 100 to 150 ml of water Descending colon mainly responsible

    Recycling of nutrients

    Nonstarch polysaccharides

    Short chain fatty acids Urea

    Ascending colon responsible

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    Colonic innervation

    Parasympathetic innervation from the vagusnerve and the pelvic autonomic center S2-S4

    Nerves are centered in plexuses along the

    subserosal and muscular components of thecolon: Auerbach and Meissner plexuses

    Controls colonic motility

    Sympathetic innervation is from the superior and

    inferior mesenteric ganglia (found by the SMAand IMA)

    Controls pain and vascular tonicity

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    Cecal anatomy

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    Appendix

    No appreciable utility

    Associated with carcinoid and primary

    appendiceal carcinomas

    Must be taken for mucinous ovarian tumors

    Appendiceal artery arises from the ileocolic

    artery and MUST be ligated

    Primary appendiceal tumors often diagnosed bygynecologic oncologists as a right ovarian tumor

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    Appendix

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    Portal circulation

    Not essential for gynecologic malignancies;however must understand the different source ofvenous drainage

    Splenic vein, SMV, IMV, gastric veins involved inthe portal system

    Portal hypertension can therefore cause,gastroesophageal varices, rectal varices andmedusae caput

    Acute bleeding has 25-30% mortality rate

    Patients with cirrhosis have a 50% mortality rate

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    Portal circulation

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    Pelvic Anatomy

    The home of the gynecologic oncologist

    Focus on blood supply, nerves of thepelvis, musculature and rectal anatomy

    Must understand the boundaries of pelviclymph node dissection

    Lateral: genitofemoral nerve

    Medial: ureter

    Inferior: deep iliac circumflex vein

    Superior: inferior mesenteric artery

    P l i bl d l

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    Pelvic blood supply Aorta

    Middle sacral artery

    Common iliac artery External iliac artery

    Inferior epigastric artery

    Deep circumflex iliac artery

    Posterior division of internal iliac artery Superior gluteal artery

    Iliolumbar artery

    Lateral sacral

    Anterior division of internal iliac artery Obturator artery

    Uterine artery

    Superior vesical artery

    Inferior vesical artery

    Umbilical ligament

    Middle rectal artery Internal pudendal artery

    Inferior rectal artery

    Labial arteries

    Dorsal artery of the clitoris

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    Pelvic blood supply

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    Pelvic blood supply

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    Common iliac artery

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    External iliac artery & vein

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    Superior vesical artery

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    Obturator space

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    Obturator nerve

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    Obturator artery

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    Obturator venous plexus

    Pelvic nerves

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    Pelvic nerves Femoral nerve

    Nerve roots L2, L3, L4

    Provides motor function to the extensor muscles Provides sensation to the thigh

    Sciatic nerve Nerve roots L4, L5, S1, S2, S3

    Largest nerve in the body

    It divides into the tibial and peroneal nerves

    Provides motor function to the distal extremity Obturator nerve

    Nerve roots L2, L3, L4

    Provides motor function to the adductor muscles

    Pudendal nerve Nerve roots S2, S3, S4

    Provides motor functions to the muscles of the pelvis and external analsphincter

    Provides sensation to the vulva and clitoris

    Genitofemoral nerve Nerve roots L1, L2

    Provides sensation to the thigh and vulva

    P l i

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    Pelvic nerves

    Pelvic nerves

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    Pelvic nerves

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    Muscles of the pelvis

    Psoas L2, L3, L4 flexes thigh

    Piriformis S1, S2 rotates thigh laterally

    Obturator internus L5, S1, S2 rotates thigh laterally

    Levator Ani Pubococcygeus S3, S4 raise pelvic floor

    Iliococcygeus

    Puborectalis

    Coccygeus S4, S5 raise pelvic floor

    Muscles of the pelvis

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    Muscles of the pelvis

    M l f th l i

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    Muscles of the pelvis

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    Bladder

    Muscular structure which functions as a reservoir forurine

    Can hold 1000 ml however most females have a strongurge to void at 400 ml

    Supplied by the superior vesical and inferior vesicalarteries

    Innervation is both parasympathetic and sympathetic

    Parasympathetic (S2, S3, S4) controls detrusorcontraction while inhibiting the internal sphincter

    Sympathetic (T11, T12, L1, L2) transmit sensation

    Bladder innervation

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    Bladder innervation

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    Rectum

    Last portion of the colon, rich blood supply, relativelymobile below the peritoneum

    Multiple layers which control continence 1st it follows the contour of the sacrum

    2nd

    the valves of houston produce sharp turns for the feces tonavigate

    3rd the puborectalis muscles forms a sling around the rectumcalled the anorectal angle

    All these layers close off the lumen with valsalva

    The pectinate line marks the transformation fromsquamous epithelium to columnar epithelium

    Blood supply stems from both the IMA and the internaliliac arteries (superior, middle, inferior rectal arteries)

    Rectum

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    Rectum

    Rectum

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    Rectum

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    Vulvar anatomy

    Layers of support to the pelvic floor

    Blood supply to the vulva Internal pudendal artery

    Inferior rectal artery

    Labial/ perineal arteries

    Dorsal artery of the clitoris External pudendal artery

    Nervous supply to the vulva Ilioinguinal nerve

    Pudendal nerve Labial/ perineal nerves

    Dorsal nerve of the clitoris

    Posterior femoral cutaneous nerve

    Points of interest with a inguinal lymphadenectomy

    Vulva: deep to superficial

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    Vulva: deep to superficial

    Vulva: deep to superficial

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    Vulva: deep to superficial

    V l d t fi i l

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    Vulva: deep to superficial

    Vulva: deep to superficial

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    Vulva: deep to superficial

    Vulva: deep to superficial

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    Vulva: deep to superficial

    Vulvar blood supply

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    Vulvar blood supply

    Vulvar blood supply

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    pp y

    Vulvar blood supply

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    pp y

    Lymphatic drainage of the vulva

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    Lymphatic drainage of the vulva

    Innervation of the vulva

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    Femoral Triangle

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    Femoral Triangle

    Borders: Inguinal ligament superiorly, sartoriusmuscle laterally and adductor longus medially

    Superficial inguinal lymph nodes above thecribriform fascia (6-8)

    Femoral nerve, artery, and vein are found belowthe cribriform fascia

    Deep inguinal lymph nodes (2-3)

    Cloquets node deepest most superior lymphnode before crossing inguinal ligament andthereby external iliac lymph nodes

    Femoral Triangle

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    g

    Muscles of the thigh

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    Muscles of the thigh

    Sartorius

    L2, L3 (F) Flexes, abducts and

    laterally rotates thigh

    Gracilus L2, L3 (O) Flexes, adducts and

    medially rotates thigh

    Adductor longus L2, L3 (O) Adducts thigh

    Femoral and Obturator Nerves

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