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Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft lacement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin, T. Konorza, H. Kälsch, H. Eggebrecht, R. Erbel Department of Cardiology West German Heart Center Essen

Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

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Page 1: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

Aortic Symposium

New York 2012

„Pseudoaneurysm After Endovascular Stent Graft

Placement for Treatment of Type B Aortic Dissection“

R.A. Jánosi, M. Bettin, T. Konorza, H. Kälsch, H. Eggebrecht, R. Erbel

Department of CardiologyWest German Heart Center Essen

Page 2: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

Patient Characteristics

no DPA DPA p

patients 143 (95 %) 8 (5 %)

male 96 (63 %) 5 (63 %) 0,786

age (y) 62,2 ± 12,8 (22-84) 60,7 ± 8,7 (48-71) 0,746

Time to Treatment (mo) 4,3 ± 11,9 20,3 ± 36,3 0,251

acute dissection 62 1 0,64

stent graft diameter (mm) 34,0 ± 5,1 33,0 ± 1,5 0,589

stent graft length (mm) 153,2 ± 43,1 158,1 ± 40,0 0,753

Angle (°) 167,1 ± 12,4 148,2 ± 16,5 <0,05

reintervention 18 (13 %) 7 (88 %)* <0,05

Time to reintervention (mo) 27,8 ± 24,6 19,1 ± 15,1 0,364

Page 3: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

Characteristics of 8 patients complicated with DPA afterEndografting for Type B Dissection

patient

Age Initial Indication Coexisting conditions

Onset timeIntervention>diagnosis DPA (mo)

Stent graft extension

Duration of follow up (mo)

DPA (mm)

Stent

1 70 Recurrent pain, impending rupture

HTN 16 yes 45 15x35 Valiant

2 59 Recurrent pain HTN 3 yes 27 22x34 Relay

3 47 Recurrent pain, Malperfusion

HTN 19 yes 27 10x16 Valiant

4 68 Recurrent pain HTN 50 yes 80 39x44 Talent

5 67 Recurrent pain HTN, MI

76 yes 109 20x34 Talent

6 65 Recurrent pain HTN, CHD

14 yes 13 13x25 Relay

7 58 Recurrent pain HTN 115 refused 115 - Talent

8 49 Progredient FL-aneurysm

HTN 26 yes 26 9x28 Valiant

Page 4: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,
Page 5: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,
Page 6: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

10,08,06,04,02,00,0

Zeit TEVAR bis Reintervention

1,0

0,8

0,6

0,4

0,2

0,0

Ver

lau

f o

hn

e R

ein

terv

enti

on

nein-censored

ja-censored

nein

ja

DistalesPseudoaneurysma

Rat

e of

free

dom

Rei

nter

vent

ion

years

DistalPseudoaneurysm

YesNoYes-censoredNo-censored

Page 7: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,
Page 8: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,
Page 9: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

When passively bent at the arch, the self-expanding stent graft has theinherent tendency to spring back toits initial straight status.

Page 10: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

When passively bent at the arch, the self-expanding stent graft has theinherent tendency to spring back toits initial straight status.

Page 11: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

Conclusions

•Endovascular treatment in chronic type B dissection has a

high technical success rate and low mortality•Pseudoaneurysm of the thoracic aorta is a rare and

potentially fatal condition•Potential mechanism:

• Trauma caused by the semi-rigid stent graft• Fragility of the aortic wall and disease progression• Excessive radial force due to distal oversizing of the

stent graft prosthesis to > 20%Development of dissection-specific, less-rigid endo-

prosthesis

Page 12: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,
Page 13: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,
Page 14: Aortic Symposium New York 2012 „Pseudoaneurysm After Endovascular Stent Graft Placement for Treatment of Type B Aortic Dissection“ R.A. Jánosi, M. Bettin,

Characteristics of 8 patients complicated with DPA afterEndografting for Type B Dissection

patient

Age Initial Indication Coexisting conditions

Oversizing

Onset timeIntervention>diagnosis DPA (mo)

Stent graft extension

Duration of follow up (mo)

DPA (mm)

Stent

1 70 Recurrent pain, impending rupture

HTN 16 yes 45 15x35 Valiant

2 59 Recurrent pain HTN 3 yes 27 22x34 Relay

3 47 Recurrent pain, Malperfusion

HTN 19 yes 27 10x16 Valiant

4 68 Recurrent pain HTN 50 yes 80 39x44 Talent

5 67 Recurrent pain HTN, MI

76 yes 109 20x34 Talent

6 65 Recurrent pain HTN, CHD

14 yes 13 13x25 Relay

7 58 Recurrent pain HTN 115 refused 115 - Talent

8 49 Progredient FL-aneurysm

HTN 26 yes 26 9x28 Valiant