Approach to leucocytosis

Jackie Thomson

LYMPHOID

MYELOID

ACUTE / IMMATURE

MATURE/ CHRONIC

LYMPHOID

MYELOID

MATU

RE

IMM

ATU

RE

B-ALLT-ALL

LYMPHOID

MYELOID

MATU

RE

IMM

ATU

RE

B-ALLT-ALL

AMLMDS

LYMPHOID

MYELOID

MATU

RE

IMM

ATU

RE

B-ALLT-ALL

CLLALL LYMPHOMAS

BURKITT LEUKAEMIAMYELOMA

AMLMDS

LYMPHOID

MYELOID

MATU

RE

IMM

ATU

RE

B-ALLT-ALL

CLLALL LYMPHOMAS

BURKITT LEUKAEMIAMYELOMA

AMLMDS

CHRONIC MYELOID LEUKAEMIAESSENTIAL THROMBOCYTOSIS

POLYCYTHEMIA VERAMYELOFIBROSIS

LYMPHOID

MYELOID

MATU

RE

IMM

ATU

RE

Child

• Infections

• Leukemia most common ALL

Adult

• Good history:– Infection– B symptoms– Tierdness– Bleeding– Burning eyes – Skin

adult

• FBC• NB look at platelets and HB• Contact the hematologist when you have a

clinical suspicion regarding patient• Remember flow cytometry• Fish• Molecular testing

adult

• Exam:• Look for spleen/ lymphnodes• Mouth ulcers • Auto immune /artritis• erythromialgia