BIBLIOGRAPHY - C. B. Anfinsen

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Anfinsen, C.B., Lowry, O.H. and Hastings, A.B.: Application of the freezing-drying technique to retinal histochemistry. J. Cell. and Camp. Physiol. 20: 231-237, 1942. -

Anfinsen, C.B.: The distribution of diphosphopyridine nucleotide in the bovine retina, J. Biol. Chem. 152: 273-284, 1944.

Anfinsen, C.B.: The distribution of cholinesterase in the bovine retina. J. Biol. Chem. 152: 267-278, 1944.

Anfinsen, C.B.: A micromanometric method for the determination of dipbosphopyridine nucleotide. J. Biol. Chem. 152: 285-291, 1944.

Ball, E.G., Anfinsen, C.B., Geiman, Q.M., McKee, R.W. and Ormsbee, R.A.: In vitro growth and multiplication of the malaria parasite Plasmodium -- knowlesi. Science 101: 542-544, 1945.

McKee, R.W., Ormsbee, R.A., Anfinsen, C-B., Geiman, Q.M. and Ball, E.G.: Studies on malarial parasites. VI. The chemistry and metabolism of normal and parasitized (P. knowlesl) monkey blood. - J. Exp. Hed. 84: - 569-582, 1946.

Geiman, Q.M., Anffnsen, C.B., McKee, R.W., Ormsbee, R.A. and Ball, E.G.: Studies on malarial parasites. VII. Methods and techniques for culti- vation. J. Exp. Med. 34: 538-606, 1946. -

Anfinsen, C.B., Geiman, Q.M., McKee, R.W., Ormsbee, R.A. and-Ball, E.G.: Studies on malarial parasites. VIII. Factors affecting the growth of Plasmodium knowlesi in vitro. J. Exp. Med. 84: 607-621, 1946.

Anfinsen, C.B.: Determination of dauterium in the gradient tube, Preparation and Measurement of Isotopic Tracers, D. Wright Wilson, Editor, J.W.Edwards, Ann Arb;;;, 1946.

Anfinsen, C.B. and Claff, C.L.: An extension of the Cartesian diver micro respirometer technique. J. Biol. Chem. 167: 27-33, 1947.

Ball, E.G., Anffnsen, C.B., and Cooper, 0.: The inhibitory action of napthoquinones on respirator processes. J. Biol. Chem. 168: 257-270, 1947.

Anfinsen, C.B., Beloff, A., Hastings, A-B. and Solomon, A.K.: The in - vitro turnover of dicarboxylic amino acids in liver slice proteins. J. Biol. Chem. 168: 771-772, 1947.

Anfinsen, C.B.: The inhibitory action of maphthoguinones on respira- tory process: the inhibition of cleavage and respiration in the eggs of Arbacia punctulata. J. Cell. and Comp. Physiol. 29: 323-332, 1947. -

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Solomon, A.K., yyld, R. 4, radiation from S and C E and Anfinsen, C.B.: Energy of beta-

. Phys. Review 72: - 1097-1100, 1947.

Pope, A. and Anfinsen, C.B.: Histochemical distribution of peptidase activity in the central nervcus system of the rat. J. Biol. Chem. 173: 305-311, 1948.

Ball, E.G., McKee, R.W., Anfinsen, C.B., Cruz, W.O. and Geiman, Q.M.: Studies on malarial parasites., IX. Chemical and metabolic changes during growth and multiplication in viva and in vitro. J. Biol. -- -- them 175: 547-571, 1943.

Beloff, A., and Anfinsen, C.B.: The products of proteolysis of some purified proteins. J. Biol. Chem. 176: .- 863-872, 1938.

Gould, R.G., Hastings, A.B., AnfinSen, C.B., Rosenberg, I.N., Solomon, A.K. and Topper, Y.J.: Metabolism of isotopic pyruvate and acetate in rabbit liver slices in vitro. J. Biol. Chem. 177: -- 727-731, 1949.

Hastings, A.B., Solomon, A.K., Anfinsen, C.B., Gould, R.G. and Rosenberg, I.N.: Incorporation of isotopic carbon dioxide in rabbit liver glycogen in vitro. J. Biol. Chem. : -- 717-726, 1949.

Anfinsen, C-B., Beloff, A. and Solomon, A.K.: The incorporation of radioactive carbon dioxide and acetate into liver proteins in vitro. -- J. Biol. Chem. 179: 1001-1013, 1949.

Buchanan, J.M., and Anfinsen, C.B.: Partial purification of aconitase. J. Biol. Chem. 180: 47-54, 1949.

Peters, T., Jr. and Anfinsen, C.B.: Production of radioactive serum albumin by liver slices. J. Biol. Chem. 182: 171-179, 1950.

Beecher, H.K., Francis, L. and Anfinsen, C.B.: Metabolic effects of anesthesia in man. J. Pharmacol. and Exp. Therap. 98: 38-44, 1950. -

Anfinsen, C.B.: Radioactive crystalline ribonuclease. J. Biol. Chem. 185: 827-831, 1950.

Peters, T.P. and Anfinsen, C.B.: Net production of serum albumin by liver slices. J. Biol. Chem. 186: - 805-813, 1950.

Anfinsen, C.B. and Steinht.rg, D.: Studies on the biosynthesis of ovalbumin. J. Biol. Chea. 189: 739-744, 1951.

Steinberg, D. and Anfinsen, C.B.: Evidence for intermediate compounds in ovalbumin synthesis. J. Biol. Chem. 199: 25-42, 1952.

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Olson, J.A. and Anfinsen, C.B.: Crystallization and characterization of L-glutamic acid dehydrogenase. J. Biol. Chem. 197: 67-79, 1952.

Anfinsen, C.B.: The peptic digestion of ribonuclease. J. Biol. Chem. - 201-208, 1952. 196:

Anfinsen, C.B., Flavin, M., Farnsworth, J.: Preliminary studies on ribonuclease structure. Biochem. et Biophys. Acta 2: 468-469, 1952.

Anfinsen, C.B., Boyle, E. and Brown, R.K.: Role of heparin in lipo- protein metabolism. Science 115: 583-586, 1952.

Gordon, R.S., Jr. Boyle, E., Brown, R.K., Cherkes, A. and Anfinsen, C-B.: The role of serum albumin in the lipemia clearing reaction. Proc. Sot. Exp. Biol. and Med. 84: - 168-170, 1953.

Anfinsen, C.B. and Horning, M.: Enzymatic degradation of the choles- terol. side chain in cell-free preparations. J. Am. Chem. Sot. 75: - 1511, 1953.

Brown, R.K., Boyle, E. and Anfinsen, C.B.: The enzymatic transfor- mation of lipoproteins. .J. Biol. Chem. 204: 423-434, 1953.

Olson, J.A. and Anfinsen, C.B.: Kinetic and equilibrium studies on crystalline L-glutamic dehydrogenase. J. Biol. Chem. 202: 841-856, 1952.

Hendler, R.W., Horning, M.G. and .Anfinsen, C.B.: The synthesis of radioactive L-glutamic acid. Arch. Biochem. and Biophys. 51;- 470- 474, 1954.

Anfinsen, C.B.: Fat metabolism. On the role of lipemia clearing factor in lipid transport. Fat Metabolism, Johns Hopkins Press, Baltimore, 93-110, 1954. -

Anfinsen, C.B., Redfield, R.R., Choate, W.L., Page, J. and Carroll, W.R.: Studies on the gross structure, cross-linkages, and terminal sequences in ribonuclease. J. Biol. Chem. 207: 201-210, 1954.

Wang, J.H., Anfinsen, C-B. and Polestra, F.M.: The self-diffusion coefficients of water and ovalbumin in aqueous ovalbumin solutions at 10". J. Am. Chem. Sot. 76: 4763, 1954. -

Hendler, R.W. and Anfinsen, C.B.: The incorporation of carbon dioxide into both carboxyl groups of glutamic acid. J. Biol. Chem. 209 : 55-62, 1954.

Stadtman, T.C., Cherkes, A., and Anfinsen, C.B.: Studies on the microbiological degradation of cholesterol. J. Biol. Chem. 206: 511-523, 1954.

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Anfinsen, C.B. and Kielley, W.W.: Biological oxidations. Annual Review of Biochemistry 23: - 17-54, 1954.

Anfinsen, C.B.: Physiological aspects of lipid transport. National Research Council Symposium on Atherosclerosis, March, 1954.

Flavin, M., and Anfinsen, C.B.: The isolation and characterization of cysteic acid peptides applied to the study of ovalbumin synthesis. J.-Biol. Chem. 211: 375-390, 1954.

Vaughan, M. and Anfinsen, C.B.: Nonuniform labelling of insulin and ribonuclease synthesized in vitro. -- J. Bio.1. Chem. 211: 367-374, 1954.

Anfinsen, C.B.: Summary - second session, National Research Council Symposium on Atherosclerosis, March 23, 1954.

Anfinsen, C.B.: Lipoprotein metabolism in the etiology of athero- sclerosis. Minnesota Medicine 38: 767-774, 1955. -

Anfinsen, C.B.: Aconitase from pig heart muscle, in Methods in Enzymology, edited by Colowick and Kaplan, Academic Press, Inz 1955.

Anfinsen, C.B.: The inactivation of ribonuclase by restricted pepsin digestion. Biochim. et Biophys. Acta I?: 593-594, 1955.

Anfinsen, C.B., Harrington, W.F., Hvidt, Aa, Linderstrdm-Lang, K., Ottesen, M. and Schellman, J.: Studies on the structural basis of ribonuclease activity. Biochim. et Biophys. Acta 17: 141-142, 1955. -

Anfinsen, C.B.: On the structural basis of ribonuclease activity. Symposium on molecular structure and biological specificity. American Institute of Biological Sciences, Washington, D-C,, October, 1955.

Anfinsen, C.B.: The limited digestion of ribonuclease with pepsin. J. Biol. Chem. 221: 405-412, 1956.

Redfield, R.R. and Anfinsen, C-B.: The structure of riobnuclease. II. The preparation, separation and relative alignment of large enzymatically produced fragments. J. Biol. Chem. 221: 385-404, 1956.

Steinberg, D., Vaughan, M. and Anfinsen, C.B.: Kinetic aspects of the assembly and degradation of proteins. Science 124: 389-395, 1956.

Anfinsen, C.B. and Redfield, R-R.: Protein structure in relation to function and synthesis, in Advances in Protein Chemistry Vol. XI, Academic Press, N.Y., pp. l-100, 1956.

Anfinsen, C.B.: Biochemical aspects of atherosclerosis. Fed. Proc. 15: - 894-899, 1956.

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Anfinsen, C.B.; Sela, M. and Tritch, H.: A method for the specific proteolytic cleavage of protein chains. Arch. Biochem. and Biophys. 65: - 156-163, 1956.

Anfinsen, C.B.: On the non-essential,nature of hydrogen bonding for the catalytic activity of ribonuclease. Compt. Rend. des Trav. du Carlsberg. S&r. Chim. 30: 13-20, 1956. -

Anfinsen, C.B.: Funzione dell'eparina nel metabolismo delle lipo- pro teine. Estratto dai Rendicanti Dell' Istituto Superiore di Sanith. Suppl. al Vol. XIX. Roma 1956. pp. 181-196.

Sela, M. and Anfinsen, C.B.: Some spectrophotometric and polarimetric experiments with ribonuclease. Biochim. et Biophys. Acta 24: 229- - 235, 1957. .

Sela, M., White, F.H., Jr. and Anfinsen, C.B.: Reductive cleavage of disulfide bridges in ribonuclease. Science.125: 691-692, 1957.

Steinberg, D., Vaughan, M., Anfinsen, C.B. and Gorry, J.: Preparation of tritiated proteins by the Wilzbach method. Science 126: 447-448, 1957.

Ryle, A.P. and Anfinsen, C.B.: Studies on the disulfide bridges in ribonuclease. Biocheim. et Biophys. Acta 24: - 633-635, 1957.

Morning, M.G., Fredrickson, D.S. and Anfinsen, C.B.: Studies on the enzymatic degradation of the cholesterol side chain. II. Requirements of the mitochondrial system. Arch. Biochem. and Biophys. 71: 266- - 273, 1957.

Anfinsen, C.B.: Structural basis of ribonuclease activity. Federa- tion Proc. 16: 783-791, 1957. -

Sela, M., Anfinsen, C.B. and Harrington, W.F.: The correlation of ribonuclease activity with specific aspects of tertiary structure. Biochim. et Biophys. Acta 26: 502-512, 1957. -

Anfinsen, C.B.: The structure of riobnuclease in relation to its enzymatic activity and physical properties. Symposium on Protein Structure, Edited by Albert Neuberger, John Wiley & Sons, Inc., N.Y. 1958.

Sela, M., White, F.H., Jr. and Anfinsen, C.B.: The reductive cleavage of disulfide bonds and its application to problems of protein struc- ture. Biochim. et Biophys. Acta 31: 417-426, 1959. -

Anfinsen, C.B.: Protein structure and biological activity, in A Symposium on Molecular Biology, Raymond E. Zirkle, ed., Univ of Chicago Press, Chicago, 1959.

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Anfinsen, C.B., lqvist, S.E.G., Cooke j.P., and JGnsson, B.: A comparative study of the structures of bovine and ovine pancreatic ribonucleases. J. Biol. Chem. 234: - 1118-1123, 1959.

Itqvist, S.E.G. and Anfinsen, C.B.: The isolation and characterization of ribonucleases from sheep pancreas. J. Biol. Chem. 234: 1112-1117, 1959.

White, F.H. and Anfinsen, C.B.: Some relationships of structure to function in ribonuclease. AM. N.Y. Acad. Sci. 81: 515-523, 1959. -

White, F.H., Jr. and Anfinsen, C.B.: On the order,of disulfide bond reduction in ribonuclease, in Sulfur in Proteins, Academic Press, - New York, pp. 279-288, 1959.

Avigan, J. and Anfinsen, C.B.: Further observations on the structure and properties of serum lipoproteins. Biochim. Biophys. Acta 31: - 249-251, 1959.

Anfinsen, C.B.: Some approaches to the study of active centers. 3. Cellular Comp. Physiol. 54: Suppl. 1, 215, 1959. -

Katz, A.M., Dreyer, W.J. and Anfinsen, C.B.: Peptide separation by two-dimensional chromatography and electrophoresis. J. Biol. Chem. 234: 2897-2900, 1959.

Brown, R.K., Tacey, B.C., and Anfinsen, C.B.: The reaction of porcine and ovine riboncuelases with antibody to bovine ribonuclease. Biochim. Biophys. Acta 39: 528, 1960. -

Anfinsen, C.B.: The Molecular Basis of Evolution, John Wiley & Sons, -- Inc., New'York, l=.

79. Anfinsen, C.B. and White, F.H., Jr.: The ribonucleases, occurrence, structure and properties. The Enzymes, Second ed., Academic Press, New York, 1961, pp. 95-122.-

80. Tuve, T.W. and Anfinsen, C.B.: Preparation and properties of spinach ribonuclease. J. Biol. Chem. 235: 3437-3441, 1960.

81. Anfinsen, C.B.: Genetic control of protein structure in bacteriophages. Fed. Proc. 20: 634-640, 1961. -

82. Haber, E. and Anfinsen, C.B.: Regeneration of enzyme activity by air oxidation of reduced, subtilisin-modified ribonuclease. J. Biol. Chem. 236: 422-424, 1961.

83. Anfinsen, C.B.: The influences of three-dimensional configuration of the chemical reactivity and stability of proteins. J. Polymer Sci. 49: - 31-49, 1961.

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Anfinsen, C.B. and Haber, E.: STudies on the reduction and reformation of protein disulfide bonds. J. Biol. Chem. 236: 1361-1363,. 1961.

Anfinsen, C.B.: Points of current interest in protein chemistry. Lab Invest. 10: 987-991, 1961. -

Anfinsen, C.B., Haber, E., Sela, M. and White, F.H., Jr.: The kinetics of formation of native ribonuclease during oxidation of the reduced polypeptide chain. Proc. Nat. Acad. Sci. 47: 1309-1314, 1961. -

Anfinsen, C.B.: Factors influencing the formation and maintenance of the secondary and tertiary structure of proteins. Presented at the Pontificia Academia Scientiarum Study Week.. Oct. 23-30, 1961. The Vatican.

Epstein, C.J., Goldberger, R.F., Young, D.M. and Aniinsen, C.B.: A study of the factors influencing the rate and extent of enzymic reactivation during reoxidation of reduced ribonuclease. Arch. Biochem. Suppl. 1: 223-231, 1962.

Anfinsen, C.B.: Some observations on the basic principles of design in protein molecules. Fifth International Congress of Biochemistry, August 10-17, 1961, Moscow. Comp. Biochem. Physiol. 4: 229, 1963. Pergamon Press.

Anfinsen, C.B., Sela, Ma and Cooke, J.P.: The reversible reduction of disulfide bonds in polyalanyl ribonuclease. J. Biol. Chem. 237: 1825-1831, 1962.

Haber, E. and Anfinsen, C.B.: Side chain interactions governing the pairing of half-cystine residues in ribonuclease. J. Biol. Chem. 237: 1839-1844, 1962.

Potts, J.T., Berger, A., Cooke, J.P. and Anfinsen, C.B.: A reinvesti- gation of the sequence of residues eleven to eighteen in bovine pancreatic ribonuclease. J. Biol. Chem. 237: 1851-1855, 1962.

Goldberger, R.F. and Anfinsen, C.B.: The reversible masking of amino groups in ribonuclease and its possible usefulness in the synthesis of the protein. Biochemistry I: 401-405, 1962.

Epstein, C.J. and Anfinsen, C.B.: The reversible reduction of disulfide bonds in trypsin and ribonuclease coupled to carboxymethyl-cellulose. J. Biol. Chem. 237: 2175-2179, 1962.

Anfinsen, C.B.: Amino acid sequence as the major determinant of structure and function in proteins. In Gellhorn, A. and Hirschberg (Eds): Basic Problems in Neoplastic Disease. Univ. Press, 1962, pp. =2-130.

New York, Columbia

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Epstein, D.J. and Anfinsen, C.B.: Reversible reduction and reoxidation of poly-DL-alanyl trypsin. J. Biol. Chem. 237: 3464-3467, 1962.

Epstein, C.J., Anfinsen, C.B. and Sela, M.: The properties of poly-DL- alanyl chymotrypsin. J. Biol. Chem. 237: 3458-3463, 1962.

Anfinsen, C.B.: Macromolecular considerations of cellular organization. In Canadian Cancer Conference. New York, Academic Press, 1963. Vol. 5, pp. 3-9.

Anfinsen, C.B.: The tertiary structure of ribonuclease. Brookhaven Symposia in Biology 15: 184-198, 1962. -

Anfinsen, C.B.: General remarks on protein structure and biosynthesis. In Symposium on Informational Macromolecules. 1963, ppa 153q66.

New York, Academic Press,

Goldberger, R.F., Epstein, C.J., and Anfinsen, C.B.: Acceleration of reactivation of reduced bovine pancreatic ribonuclease by a microsomal system from rat liver. J. Biol. Chem. 238: 628-635, 1963.

Epstein, C.J. and Anfinsen, C.B.: The use of gel filtration in the isolation and purification of beef insulin. Biochem. 2: 461-464, May- June 1963.

Cooke, J.P., Anfinsen, C.B. and Sela, M.: The identification of un- reactive amino groups in ribonuclease and their significance to enzymatic activity. J. Biol. Chem. 238: 2034-2039, 1963.

Canfield, R.E., and Anfinsen, C.B.: Chromatography of pepsin and chymotrypsin digests of egg white lysozyme on phosphocellulose. J. Biol. Chem. 238, 2684, 1963.

Canfield, R.E. and Anfinsen, C.B.: Nonuniform labeling of egg white lysozyme. Biochem. 2: 1073-1078, 1963.

Canfield, R.E. and Anfinsen, C.B.: Concepts and experimental approaches in the determination of -he primary structure of proteins. In Neurath, H. (ed): The c'roteins. New York, Academic Press, 1963. Vol 1, pp. 311-378. -

Anfinsen, C.B., Rumley, M.K., and Taniuchi, H.: Structural and enzymatic properties of the extracellular nuclease of micrococcus pyogenes. Acta Chemica Stand. 17: - 270-276, 1963.

Potts, J.T., Jr., Young, D.M. and Anfinsen, C.B.: Reconstitution of fully active RNase S by carboxypeptidase-degraded RNase S-peptide. J. Biol. Chem. 238: 2593-2594, 1963.

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Brown, R.K., Trzpis, M.A., Sela, M. and Anfinsen, C.B.: Studies on the antigenic structure of riobnuclease. IV. Polyalanyl ribonuclease. J. Biol. Chem. 238: 3876-3883, 1963.

Epstein, C.J., Goldberger, 'R.F. and Anfinsen, C.B.: The genetic control of tertiary protein structure: studies with model systems. Cold Spr. Harb. Symp. on &ant. Biol. XXVIII, 439-449, 1963.

Anfinsen, C.B.: On the possibility of predicting tertiary structure from primary sequence. In Sela, M. (Ed), New Perspectives in Biology. Amsterdam, The Netherlands, Elsevier Pub. co., 1964. pp. 4z50.

Goldberger, R.F., Epstein, C.J. and Anfinsen, C.B.: Purification and properties of'a microsomal enzyme system catalyzing the reactivation of reduced ribonuclease and lysozyme. J. Biol. Chem. 239: 1406- 1410, 1964.

Potts, J.T., Jr., Young, D.M., Anfinsen, C.B. and Sandoval, A.: Studies on ribonculease S. I. Limited carboxypeptidase degradation of ribonuclease S-protein and ribonuclease S-peptide: effects of changes in primary structure on enzymic activity. J. Biol. Chem. 239: 3781-3786, 1964.

Givol, D., Goldberger, R.F. and Anfinsen, C.B.: Oxidation and disulfide interchange in the reactivation of reduced ribonuclease. J. Biol. cbem. 239: 3114-3116, 1964.

Craven, G.R., Steers, E., Jr., and Anfinsen, C.B.: Purification, Composition, and molecular weight of the B-galactosidase of Escherichia

- K12* coli J. Biol. Chem. 240: 2468-2477, 1965.

Steers, E., Jr., Craven, G.R., Anfinsen, C.B. and Bethune, J.L.: Evidence for non-identical chains in the B-galactosidase of Escherichia coli - Q* J* Givol, D., DeLorenzo, F., Disulfide interchange and Proc. Nat. Acad. Sci. 53: -

Biol. Chem. 240: 2478-2484, 1965.

Goldberger, R.F. and Anfinsen, C.B.: the three-dimensional structure of proteins.

676-684, 1965.

Anfinsen, C.B.; Molecular structure and the function of proteins. In Allen, J.M. (Ed): Molecular Organization and Biological Function (Modern Perspectives in Biology). New YorcHarper & Row, 1966, pp. 1-19.

Givol, D., Craven, G.R., Steers, E., Jr. and Anfinsen, C.B.: Effect of limited digestion by proteolytic enzymes on Escherichia coli B-galactosidase. Biochem. Bfophys. Acta 113: 120-125, 1966.

Steiner, R.F., DeLorenzo, F. and Anffnsen, C.B.: Enzymically-catalyzed disulfide interchange in randomly cross-linked soy bean trypsin inhibitor. J. Biol. Chem. 240: 4648-4651, 1965.

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121. Steers, E., Jr., Craven, G.R. and++finsen, C.B.: Comparison of B-gafa$tosidases from normal (k o z ) and operator constitutive (i 0 2 ) strains of E. coli. Proc. Nat. Acad. Sci. 54: 1174-1181 1965.

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122. Korenman, S.G., Craven, G.R. and Anfinsen, C.B.: Determination of the carboxyl-terminal amino acid residue of the 8-galactosidase of . Escherichia coli - K12* Biochim. Biophys. Acta 124: 160-165, 1966.

123. DeLorenzo, F., Goldberger, R.F., Steers, E., Jr., Givol, D. and Anfinsen, C.B.: Purification and properties of an enzyme from beef liver which catalyzes sulfhydryl-disulfide interchange in proteins. J. Biol. Chem. 241: 1562-1567, 1966.

124. Heins, J.N., Suriano, J.R., Taniuchi, H. and Anfinsen, C.B.: Char- acterization of a nuclease produced by Staphylococcus aureus. J. Biol. Chem. 242, 1016-1020, 1967.

125. Taniuchi, H. and Anfinsen, C.B;: The amino acid sequence of an extracellular nuclease of Staphylococcus aureus. I. Linear order of the fragments produced by cleavage with cyanogen bromide. J. Biol. Chem. 241: __ 4366-4385, 1966.

126. Anfinsen, C.B.: The formation of the tertiary structure of proteins. Harvey Lectures, Series 61, 1967. Academic Press, Ic., New York, p. 95.

127. Fuchs, S., DeLorenzo, F. and Anfinsen, C.B.: Studies on the mechanism of the enzymic catalysis of disulfide interchange in proteins. J. Biol. Chem. 242: 298-402, 1967.

128. DeLorenzo, F., Fuchs, S. and Anfinsen, C.B.: Characterization of a peptide fragment containing the essential half-cystine residue of a microsomal disulfide interchange enzyme. Biochem. 2: 3961-3965, 1966.

129. Cuatrecasas, P., Fuchs, S., and Anfinsen, C.B.: Catalytic properties and specificity of the extracellular nuclease of Staphylococcus aureus. J. Biol. Chem. 242: 1541-1547, 1967.

130. Cuatrecasas, P., Fuchs, S., and Anfinsen, C.B.: The binding of nucleotides and calcium to the extracellular nuclease of Staphylococcus aureus: studies by gel filtration. J. Biol. Chem. 242: 3063-3067, 1967.

131. Taniuchi, H., Anfinsen, C.B. and Sodja, A.: The amino acid sequence of an extracellular nuclease of Staphylococcus aureus. II. The amino acid sequences of tryptic and chymotryptic peptides. J. Biol. Chem. 242: 4736-4751, 1967.

132. Taniuchi, H., Anfinsen, C.B. and Sodja, A.: The amino acid sequence of an extracellular nuclease of Staphylococcus aureus, V8. III. Complete amino acid sequence. J. Biol. Chem. 242: 4752-4758, 1967.

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133. Cuatrecasas, P., Fuchs, S. and Anfinsen, C.B.: The interaction of nucleotides with the active site of staphplococcal nuclease: spectrophotometric studies. J. Mol. Chem. 242: 4759-4767, 1967.

134. Fuchs, S., Cuatrecasas, P. and Anfinsen, C.B.: An improved method for the purification of staphylococcal nuclease. J. Biol. Chem. 242: 4768-4770, 1967.

135. Taniuchi, H., Anfinsen, C.B. and Soclja, A.: Nuclease-T: an active derivative of staphylococcal nuclease composed of two noncovaleatly bonded peptide fragments. Roe, Nat. Acad. Sci. U.S.A. 58: 123% 1242, 1967.

136. Anfinsen, C-B., Ontjes, D., Ohno;M., Corley, L. and Eastlake, A.: The synthesis of protected peptide fragments of a staphylococcal nuclease. Proc. Nat. Acad. Sci. U.S.A. 2: 1806-1811, 1967.

l.37.. Ohno, M. and Anfinsen, C.B.: Removal of protected peptides by hydrazinolysis after solid phase synthesis. J. Am. Chem. Sot. 89: 59944995, 1967;

138. Cuatrecasas, P., Edelhoch, 8. and Anfinsen, C.B.: Fluorescence studies of the interaction of nucleotides with the active site of the nuclease of Stanhylococcus aureus. Roe. Nat. Acad. Sci. U.S.A. 2: 2043- 2050,% 1967.

139. Cuatrecasas, P., Fuchs, S. and Anfinsen, C.B.: The effect of a competitive inhibitor on the acetylation of tprosyl and lysyl residues of staphylococcal m&ease. Biochim. Biophys. Acta : 417-419, 1968 .

140. Cusumano, C.L., Taniuchi, H., and Anfinsen, C.B.: Stqphylococcal nuclease (Foggi strain). I. Order of cyanogkn bromide fragments and a "fourth" bistidine. J. Biol. Chem. 43: 4769-4777, 1968.

141. Taniuchi, H. and Anfisen, C.B.: Steps in the formation of active derivatives of staphylococcal nuclease during trypsin digestion. J. Biol. Chem. 243: 4778-4786, 1968.

142. Cuatrecasas, P., Fuchs, S. and Anfibsen, C.B.: The tyrosyl residues at the active site of staphylococcal nuclease: modifications by tetranitromerhane. J. Biol. Chem. 243: 4787-4798, 1968.

143. Cuatrecasas, P., Taniuchi, H., Anfinsen, C.B. and Ontfes, D.: The structural basis of the catalytic function of staphylococcal nuclease. Brookhaven Symp, Biol. 2: 172-200, 1968.

144. Anfinsen, C.B.: Spontaneous formation of the three-dimensional structure of proteins. Proc. 27th Symp. Sot. Study of Devel. 6 Crovth, June 19-21, 1968, Ithaca, pp. l-20.

12.

145. Fuchs, S., Cuatrecasas, P., Ontjes, D.A. and Anfinsen, C.B.: Correlation between the antigenic and catalytic properties of staphylococcal nuclease. J. Biol. Chem. 244: 943-950, 1969.

146. Anfinsen, C.B.: Characterization of staphylococcal nuclease and the status of studies on its chemical' synthesis. Proc. 5th Int. Symp. Chem. of Natural Products, July 8-13, 1968. London. Pure and Applied Chem. 17: - 461-487, 1968,

147. Cuatrecasas, p., Wilchek, M. and Anfinsen, C.B.: Selective enzyme purificaton by affinity chromatography. Proc. Nat. Acad. Sci. 61: 636-643, 1968.

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148. Cuatrecasas, P., Fuchs, S. and Anfinsen, C;B.: Crosslinking of aminotyrosyl residues in the active site of staphylococcal nuclease. J. Biol. !Zhem. 244: 406-412, 1969. ' .

149. Ontjes, D.A. and Anfinsen, C.B.: Solid phase synthesis of a polypeptide sequence from staphylococcal nuclease. Proc. 1st Amer. Peptide Symp., August 11-15, New Haven, Conn. 1968.

150. Omenn, G.S. and Anfinsen, C.B.: Solid phase peptide coupling. J. Am. 3mr1. Sot. 90, 6571-6572, 1968.

151. Cuatrecasas, P., Wilchek, M. and Anfinsen, C.B.: Staphylococcal Nuclease: on the size and specificity of the active site. Science 162: 1491-1493, 1968.

152. Moravek, L., Anfinsen, C.B., Cone, J.L. and Taniuchi, H.: The large scale preparation of an extracellular nuclease of Stpahylococcus aureus. J. Biol. Chem. 244: 497-499, 1969.

153. Schechter, A.N., Moravek, L. and Anfinsen, C.B.: Suppression of hydrogen exchange in staphylococcal nuclease by ligands. Proc. Nat. Acad. Sci. 61: 1478-1493, 1968. -

154. Kato, I. and Anfinsen, C.B.: On the stabilization of ribonuclease-s- protein by rfbonuclease-S-peptide. J. Biol. Chem. 244: 1004-1007, 1969.

155. Cuatrecasas, P., Milchek, M. and Anfinsen, C.B.: The action of staphylococcal nuclease on synthetic substrates. Biochem. 8: 2277- 2284, 1969.

156. Taniuchi, H. and Anfinsen, C.B.: An experimental approach to the study of the 'folding of staphylococcal nuclease. J. Biol. Chem. 244: 3864-387’5, 1969.

157. Cuatrecasas, P., Wilchek, M. and Anfinsen, C.B.: Affinity labeling of the active site of staphylococcal nuclease. Reactions with bromoacetylated substrate analogues. J. Biol. Chem. 244: 4316- 4329, 1969.

13.

158. Schechter, A.NI, Moravek, L. and Anfinsen, C.B.: Hydrogen exchange in proteins as a measure of solvent exclusion due to ligands: nuclease and myoglobin. J. Biol. Chem. 244: 4981-4988, 1969.

159. Taniuchi, H., Moravek, L. and Anfinsen, C.B.: Ligand-induced resistance of staphylococcal nuclease and nuclease-T to proteolysis by subtilisin, a-chymotrypsin and thermolysin. J. Biol. Chem. 244: 4600-4606, 1969.

160. Gntjes, D.A. and Anfinsen, C.B.: Solid phase synthesis of a 42 residue fragment of staphylococcal nuclease: properties of a semi- . synthetic enzyme. Proc. Nat. Acad. Sci. 64: 428-435, 1969. -

164 Kato, I. and Anfinsen, C.B.: Purification of synthetic RNase-S- peptide derivatives by specific complex formation on columns of RNase- R-protein bound to agarose. J. Biol. Chem. 244: 5849-5866, 1969.

162. Anfinsen, C.B. and Corley, L.G.: An active variant of staphylococcal nuclease protected carboxyl-terminal tetradecapeptide sequence of staphylococcal nuclease. J. Am. them. Sot. 91: 6842-6846, 1969. -

163. Ohno, M., Eastlake, A., Ontjes, D.A. and Anfinsen, C.B.: Synthesis of a fully protected carboxyl-terminal tetradecapeptide sequence of staphylococcal nuclease. J. Am. Chem. Sot. 91: 6842-6846, 1969. -

164. Omenn, G.S., Ontjes, D.A. and Afnisnen,' C.B.: Fractionation of antibodies 'against staphylococcal nuclease on Sepharose immunoadsorbents. Nature 225: - -189-190, iSjO.

165. Ontjes, D.A. and Anfinsen, C.B.: Synthetic studies of structure- function relationships in staphylococcal nuclease: synthetic analogues of fragment P2. J. Biol. Chem. 244: 6316-6322, 1969.

166. Omenn, G.S., Cuatrecasas, P. and Anfinsen, C.B.: Studies of the aromatic circular dichroism of staphylococcal nuclease. Proc. Nat. Acad. Sci. 64: 923-930, 1969. -.

167. Schechter, A.N., Chen, R.F. and Anfinsen, C.B.: The kinetics of the folding of stpahylococcal nuclease. Science 167: 886-887, 1970.

168. Omenn, G.S., Fontana, A. and Anfinsen, C.B.: Modification of the single tryptophan residue of staphylococcal nuclease by a new mild oxidizing agent. J. Biol. Chem. 245: 1895-1902, 1970.

169. Anfinsen, C.B., Ontjes, D.A. and Chaiken, I.M.: Synthetic analogues of a biologically active fragment of staphylococcal nuclease. Proc. 10th European Symp. Peptides 1969.

170. Omenn, G.S., Ontjes, D.A. and Anfinsen, C.B.: Immunochemistry of staphylococcal nuclease. I. Physical, enzymatic, and immunological studies of chemically modified derivatives. Biochem. 2: 304-312,. 1970.

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171. Omenn, G.S., Ontjes, D.A. and Anfinsen, C.B.: Immunochemistry of staphylococcal nuclease. II. Inhibition and binding studies with sequence fragments. Biochem. 2: 313-321, 1970.

172. Chaiken, I.M. and Anfinsen, C.B.: A study of the role of histfdine residue 46 in staphylococcal nuclease by solid phase peptide synthesis. J. Biol. Chem. 245: 2337-2341, 1970.

173. Cuatrecasas, P. and Anfinsen, C.B.: Affinity chromatography. Methods in Enzymology, vol. XXII, New York, Academic Press. 1971, p. 345-378.

174. Ohno, M. and Anfinsen, C.B.: Partial enzymic deprotection in the synthesis of a protected octapeptide bearing a free terminal carboxyl group. J. Am. Chem. Sot. 92: 4098-4102, 1970. -

175. Chaiken, I.M. and Anfinsen, C.B.: A solid phase synthetic study of structure-function relationships in the amino-terminal region of staphylococcal nuclease. J. Biol. Chem. 245: 4718-4723, 1970.

176. Chaiken, I.M. and Anfinsen, C.B.: A solid phase synthetic study of the active site region of staphylococcal nuclease-T. J. Biol. Chem. 246: 2285-2290, 1971.

177. Taniuchi, H. and Anfinsen, C.B.: Simultaneous formation of two alternative enzymically active structures by complementation of two overlapping fragments of stpahylococcal nuclease. J. Biol. Chem. 246: 2291-2301, 1971.

178. Anfinsen, C.B., Schechter, A.N. and Taniuchi, H.: Some aspects of the structure of staphylococcal nuclease. Part II. Studies in solution. Cold Spr. Harb. Symp. &ant. Biol. XXVI: 249-255, 1971.

179. Cuatrecasas, P. and Anfinsen, C.B.: Affinity chromatography. Ann. Review of Biochem. 40: - 259-278, 1971.

180. Anfinsen, C.B., Cuatrecasas, P. and Taniuchi, H.: Staphylococcal nuclease, chemical properties and catalysis. The Enzymes, Vol. IV. New York, Academic Press, Inc., 1971. pp. 177-204.

181. Izumiya, N. and Anfinsen, C.B.: Synthesis of phenylalanyl-arginyl- leucyl-aspartic acid: a model study of the coupling of arginine- terminal tryptic fragments of proteins. Arch. Biochem. Biophys. 3: 237-244, 1971.

182. Cone, J.L., Cusumano, C.L., Taniuchi, H. and Anfinsen, C.B.: Staphylococcal nuclease (Foggi strain). II. The amino acid sequence. J. Biol. Chem. 246: 3103-3110, 1971.

183. Epstein, H.F., Schechter, A.N., Chen, R.F. and Anfinsen, C-B.: The folding of stphylococcal nuclease: kinetic studies of two processes in acid renaturation. J. Mol. Biol. 600 499-508, 1971. --

184. Arson, R., Maron, E., Sela, M. and Anfinsen, C.B.: Antibodies reactive with native oysozyme elicited by a completely synthetic antigen. Proc. Nat. Acad. Sci. U.S.A. 68: 1450-1455, 1971. -

185. Anfinsen, C.B.: Synthetic analogues of staphylococcal nuclease: studies of activity and conformation. Proc. 23rd Int. Cong. of Pure and Applied Chemistry, July 1971, Boston, Mass.

186. Parikh, I., Corley, L. and Anfinsen, C.B.: Semi-synthetic analogues of an enzymically active complex formed between two overlapping fragments of staphylococcal nuclease. J. Biol. Chem. 246: 7392- 7397, 1971.

187. Taniuchi, H., Davies, D.R., and Anfinsen, C.B.: A comparison of the X-ray diffraction patterns of crystals of reconstituted nuclease-T and of native staphylococcal nuclease. J. Biol. Chem. 247: 3362- 3364, 1972. .

188. Zeiger, A. and Anfinsen, C.B.: Progress of the classical synthesis of "fragment P2" (residues 6-47) of staphylococcal nuclease-T. Prog. Peptide Research Vol. 2, pp. 307-316, 1972.

189. Corley, L., Sachs, D.H. and Anfinsen, C.B.': Rapid solid-phase synthesis of bradykinin. Biochem. Biophys. Res. Comm. 47: 1353- - 1359, 1972.

190. Anfinsen, C.B.: The formation and stabilization of protein structure. The Sixth Jubilee Lecture. Biochem. J. 128: 737-749, 1972.

191. Sachs, D.H., Schechter, A.N., Eastlake, A. and Anfinsen, C.B.: Inactivation of staphylococcal nuclease by the binding of antibodies to a distinct antigenic determinant. Biochemistry 11: 4268-4273, - 1972.

192. Zeiger, A. and Anfinsen, C.B.: Synthesis of a fully protected heptacosapeptide norleucine analogue corresponding to positions 20-47 of the Primary structure of. stpahylococcal nuclease. J. Am. Chem. sot. 95.: - 880-886, 1973.

193. Sachs, D.H., Schechter, A., Eastlake, A. and Anfinsen, C.B.: Antibodies to a distinct antigenic detemrinant of staphylococcal nuclease. J. Immunol. 109: 1300-1310, 1972.

194. Sachs, D.H., Schechter, A., Eastlake, A. and Anfinsen, C.B.: An immuno- logic approach to the conformational equilibria of polypeptides. Proc. Nat. Acad. Sci. U.S.A. 690 -- 3790-3794, 1972.

195. Sanchez, G.R., Chaiken, I.M. and Anfinsen, C.B.: Structure-function relationships at the active site of nuclease-T'. J. Biol. Chem. 248: 3653-3659, 1973.

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196. Fisher, W.R., Taniuchi, H. and Anfinsen, C.B.: On the role of heme in the formation of the structure of cytochrome c. J; Biol. Chem. 248: 3188-3195, 1973.

197. Anfinsen, C.B.: Studies on the principles that govern the folding of protein chains. Les Prix Nobel En 1972.

198. Anfinsen, C.B.: Princip'les that govern the folding of protein chains. Science 181: 223-230, 1973) (Nobel Lecture).

199. Peters, T., Taniuchi, H. and Anfinsen, C.B.: Affinity chromatography of serum albumin with fatty acids immobilized on agarose. J. Biol. Chem. 248: 2447-2451, 1973.

200. Dunn, B.M., D.iBello; C. and Anfinsen, C.B.: The pH-dependence of the st ady state kinetics parameters for stpahylococcal nuclease catalyzed hydrolysis of deoxythymidine-d'-phosphate-5'-p-nitrophenylphosphate in B20 and D20. J. Biol. Chem. 248: 4769-4774, 1973.

201. Furie, B., Eastlake, A., Schechter, A.N. and Anfinsen, C.B.: The interaction of the lanthanide ions with staphylococcal nuclease. J. Biol. Chem. 248: 5821-5825, 1973.

202. Fuchs, S., Sela, M. and Anfinsen, C.B.: Nuclease-coated bacteriophage: a sensitive tool for studying antigenic reactivity of synthetic sequence fragments. Arch. Biochem. Biophys. : 601-605, 1973.

203. Dunn, B.M., Anfinsen, C.B..and Shrager;R.I.: Kinetics of Woodward's reagent K hydrolysis and reaction with staphylococcal nuclease. J. Biol. Chem. 249: 3717-3723, 1974.

204. Furie, B., Schechter, A.N., Sachs, D.H. and Anfinsen, C.B.: Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease. Biochemistry 13: 1561-1566, 1974. -

205. Eastlake, A., Sachs, D.H., Schechter, A.N. and Anfinsen, C.B.: Binding of univalent antibody fragments to a distinct antigenic determinant of staphylococcal nuclease. Biochemistry z: 1567-1571, 1974.

206. Sachs, D.H., Schechter, A.N., Eastlake, A. and Anfinsen, C-B.: An immunologic distinction between possible origins of enzymatic activity in a polypeptide fragment of stpahylococcal nuclease. Nature 251: 242-244, 1974.

207. Anfinsen, C.B., Bose, S., Corley, L. and Gurari-Rotman, D.: Partial purification of human interferon by affinity chromatography. Proc. Nat. Acad. Sci. U.S.A. 710 -* 3139-3142, 1974.

208. Anfinsen, C.B.: The Weizmann Institute of the past 15 years. Rehovot, 1974.

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209. Furie, B., Schechter, A.N., Sachs, D.H. and Anfinsen, C.B.: An izmunclogical approach to the conformational equilibrium of staphylococcal nuclease. J. Mol. Biol. 92: 497-506, 1975.

* 210. Anfinsen, C.B. and Scheraga, H.A.: Experimental and theoretical

aspects of protein folding. In Anfinsen, C.B., Edsall, J.T. and Richards, F.M. (Eds): Advances in Protein Chemistry. New York, Academic Press, Inc., 1975, Vol.29, pp. 205-300.

211. Bose, S., Gurari-Rotman, D., Ruegg, U.Th., Corley, L. and Anfinsen, C.B.: Apparent dispensability of the carbohydrate moiety of human interferon for antiviral activity. J. Biol. Chem. 251: 1659-1662, 1976.

212. Anfinsen, C.B.: One Hundred Years of Originality, Quality and Style. (Lecture given at the Centennial of the Carlsberg Laboratory, Copenhagen, September 27, 1976). Carlsberg Res. Commun. 41: 293-298, 1976.

213. Bridgen, P.J., Anfinsen, C.B., Corley, L., Bose, S., Zoon, K.C., Rcegg, U.Th. and Buckler, C.E.: Human lymphoblastoid interferon: large scale production and partial purification. J. Biol. Chem. 252: 6585-6587;1977.

214. Zoon, K.C., Smith, M-E., Bridgen, P.J., zur Nedden, D. and Anfinsen, C.B.: Purification of human lymphoblastoid interferon. Interferon Workshop, Sloan-Kettering, 1979.

215. Anfinsen, C.B.: Biological synthesis of peptide hormones. Miles Symposium, 1979.

216. Zoon, K.C., Smith, M.E., Bridgen, P.J., zur Nedden, D. and Anfinsen, C.B..: Purification and partial characterization of human lymphoblastoid interferon. Proc. Natl. Acad. Sci. USA 76: 5601-5605, 1979.

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217. Zoon, K.C., Smith, M.E., Bridgen, P.J. and Anfinsen, C.B.: Amino terminal sequence of the major component f human lymphoblastoid interferon. Science 207: 527-528, 1980.

218. Zoon, KC., Smith, M.E., Bridgen, P.J., zur Nedden, D., Miller, D.M. and Anfinsen, C.B.: Human lymphoblastoid interferon: purification, amino acid composition and amino-terminal sequence. Ann. N.Y. Acad. sci. 350: 390-398, 1980.

219. Anfinsen, C.B.: Human interferon. Interdisciplinary Science Reviews 5: 110-118, 1981.

220. Smith, M.E., Komoriya, A. and Anfinsen, C.B.: Chemical Synthesis and Properties of Fragments of Human Leukocyte Interferon. In deMaeyer, E., Galasso, G. and Schellekens, H. (Eds): The Biology of the Interferon -- System. New York, Elsevier/North Hollandiomed. Press, 1981.

18.

221. Anfinsen, C.B.: The use of affinity chromatography in the study of protein folding, in Bffinitv ChromatoeraDhy &,Bioloeical Recoznition, I. Chaiken, M. Wilchek, I. Parikh (Eds.). Orlando, Academic Press, 1983, pp. 355-361.

222. Meadow, N., P. Coyle, A. Komoriya, C.B. Anfinsen, and S. Roseman: Limited proteolysis of IIIalC, a regulatory protein of the phosphoenolpyruvate:glycose phosphotransferase system, by membrane-associated enzymes from Salmonella gvohimurium and Bscherichia m. J. Biol. Chem. a: 13504-13509, 1986.

223. Anfinsen, C.B.: Classical protein chemistry in a world of slicing and splicing, in Protein maineerinp, I. Masayori, R. Sarma (Eds.), Orlando, Academic Press, 1986, pp. 3-13.

224. Rudzki, J., D. Shortle, C.B. Anfinsen, and L. Brand: Intrinsic fluorescence of wild type in mutant forms of staphylococcal nuclease. Biochemistry, submitted for publication 1987.

225. Skaja, A.K., C.B. Anfinsen, and M. Kelly. Use of high performance liquid affinity chromatography for protein recovery and thermostability analysis. November 1988. AIChE Annual Meeting, Wash., D.C. 1988.

226. Laderman, K.A., B.R. Davis, H.C. Krutzsch, M.C. Lewis, and C.B. Anfinsen. The purification and characterization of an extremely thermostable cr-amylase from the hyperthermophilic archaebacterium Pvrococcus furiosus. J. Biol. Chem 268 -9 -, 24394-24401, 1993.

227. Ladennan, K.A., K. Asada, T. Uemori, H. Mukai, Y. Taguchi, I. Koto and C.B. Anfinsen. a-Amylase from the hyperthermophilic archaebacterium Pvrococcus furiosus. Cloning and sequencing of the gene and expression in Bscherichia coli. J. Biol. Chem., m, 24402-24407, 1993.

228. Stagsted, J., C. Mapelli, C. Meyers, B.W. Matthews, C.B. Anfinsen, A. Goldstein and L. Olsson. Amino acid residues essential for biological activity of a peptide derived from a major histocompatibility complex class I antigen. Proc. Natl. Acad. Sci. USA 90, 7686-7690, 1993.