Bio Chem 07

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    Before we study the

    digestion system, we

    need to know a littlemore about the food

    that we put intoit.

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    Why is food necessary?

    -every living thing requires a constant supply of energy andmolecules

    -The 200 000 chemical reactions that take place in the cells of

    your body is called metabolism

    Catabolic(catabolism)

    large chemicals

    broken down intosmaller

    Anabolic (anabolism)-

    complex chemicals

    built from smaller onesWhat does this sound

    like???

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    Food supplies us with:

    Macronutrients: carbohydrates, fats(lipids),proteins

    Micronutrients: vitamins and minerals

    Special Nutrient Water: involved in most

    chemical reactions in the body

    We will concentrate on the macronutrients!!

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    What do we use macronutrients for?

    make new cells

    replace old and/or damaged cells

    help tissues to grow

    supply energy to the cells for cellular processes,this includes the physical and mental activities ofthe body (this is why we eat breakfast before anexam)

    Note: All the macronutrients are organic compounds(contain the element carbon)

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    MACRONUTRIENTS

    CARBOHYDRATES PROTEINS FATS

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    CARBOHYDRATES (pages 242-245)

    means carbon water basically sugars in the ratio of

    1 carbon: 2 hydrogens: 1 oxygen

    formula of a hexose sugar ______________ A. Monosaccharides the simplest sugars that are thebuilding blocks for all the other sugars

    Examples are

    glucose, most important sugar in the body

    fructose, fruit sugar

    galactose, makes up milk sugar

    All are isomers of each other

    Same formula, different structures

    What is similarabout these

    words?

    Lets see glucose! http://

    cheminf.cmbi.ru.nl/wetche/organic/

    http://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.html
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    B. Disaccharides

    These are made up of two monosaccharides

    Examples are

    Sucrose table sugar

    Lactose milk sugar

    Maltose seeds of germinating plants

    Formed by the process of dehydrolysis synthesis

    Taking away a water molecule to join two molecules together

    What is the formula for a disaccharide?

    ________________________________

    Did you know that someone who is lactose intolerant does not

    have the ability the break lactose down into themonosaccharides glucose and galactose?

    The build up of lactose causes discomfort!

    http://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.html
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    C. Polysaccharides

    Many monosaccharides joined together

    Some examples Cellulose component of plant cell walls that is impossible for

    humans to digest

    Starch plants store energy as starch, which is easy to digest (up

    to 4 hours) Glycogen animals store this form in liver and muscles, when

    the body needs glucose the liver breaks down glycogen and

    releases glucose into the blood (*this is not found in plants*)

    http://cheminf.cmbi.ru.nl/wetche/organic/gluc/glucindex.htmlhttp://niko.unl.edu/bs101/pix/glycogen.gifhttp://images.google.ca/imgres?imgurl=http://www.bmb.psu.edu/courses/bisci004a/chemtutor/polysac2.jpg&imgrefurl=http://www.bmb.psu.edu/courses/bisci004a/chemtutor/carbs.htm&h=397&w=547&sz=103&tbnid=qOgtHAYUhB0J:&tbnh=94&tbnw=129&start=30&prev=/images%3Fq%3Dstarch%26start%3D20%26hl%3Den%26lr%3D%26sa%3DN
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    http://www.wisc-online.com/objects/index_tj.asp

    http://

    science.nhmccd.edu/biol/macmole.html

    http://www.wisc-online.com/objects/index_tj.asp?objid=AP13104http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://www.wisc-online.com/objects/index_tj.asp?objid=AP13104
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    MACRONUTRIENTS

    CARBOHYDRATES PROTEINS FATS

    http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.html
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    PROTEINS (page 249-251) Why do we need them?

    Structural components of ourcells (especially nerves,

    muscles, skin and hair)

    Used to make antibodies andenzymes

    Can provide us with energy

    (not the main function)

    Our bodys arrangement of

    proteins determines who we

    are

    http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.html
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    We digest protein into the smaller amino acids

    which are absorbed and stored in our cells untilthey are needed

    These amino acids are then directed by the DNAto form proteins the body needs

    All amino acids must be present, or the protein isdismantled

    What happens when we eat protein?

    http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.html
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    What do they look like?

    They are chains (8 thousands) of amino acids

    There are 20 amino acids 8 of which are

    essential because we cannot make them

    Lets see!!

    http://trc.ucdavis.edu/biosci10v/bis10v/week2/2webi

    two amino acids join together in the process ofdehydration synthesis

    http://

    www.tvdsb.on.ca/westmin/science/sbioac/biochem/a

    Two amino acids are called a dipeptide

    Many amino acids are called a polypeptide

    http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://trc.ucdavis.edu/biosci10v/bis10v/week2/2webimages/ch5-amino-acids.jpghttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://trc.ucdavis.edu/biosci10v/bis10v/week2/2webimages/ch5-amino-acids.jpg
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    What can happen to proteins?

    Denaturation small changes that occur due to heatand pH, but can be reversed

    Coagulation permanent damage to the protein

    FYI sickle cell anemia is an error in the assembly of

    2 of the 600 amino acids that make up a red blood

    cell, causing it to be abnormally shaped

    http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304

    http://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.johnkyrk.com/aminoacid.htmlhttp://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304
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    MACRONUTRIENTS

    CARBOHYDRATES PROTEINSFATS

    (LIPIDS)

    http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304
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    FATS (LIPIDS) Page 246-247

    What are lipids?

    Class of organic compounds that are non-polar

    so they are insoluble in waterYou need to be familiar with 3 types:

    Triglycerides

    Phospholipids

    Waxes

    http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304
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    Why do we need lipids?

    Important for storage of energy

    100 g of fat = 3870 kJ of energy 100 g of carbos = 1680 kJ of energy

    Key components in cell membranes

    Cushions organsNeeded for fat soluble vitamins

    Used to make hormones

    Used to maintain body temperature

    http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304
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    Types of lipids?

    1. Triglycerides

    Made up of 1 glycerol and 3 fatty acids

    What do you think a diglyceride or monoglyceridelooks like?

    http://www2.nl.edu/jste/lipids.htm

    http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www.wisc-online.com/objects/index_tj.asp?objid=AP13304http://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htm
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    There are two types of unsaturated lipids:

    Monounsaturated only one double bond

    Polyunsaturated 2 or more double bonds

    http://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htm
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    Made up of glycerol and 2 fatty acids and aphophate/choline group

    This molecule has a polar and non polar end (just like

    the cell membrane)

    2.___________________________

    http://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htm
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    3. WaxesFatty acids attached to carbon rings

    Very stable insoluble moleculesUsed for waterproofing leaves or animal fur

    and/or feathers

    http://www.wisc-online.com/objects/index_tj.asp?

    =AP13204

    Review:http://science.nhmccd.edu/biol/dehydrat/dehydrat.html

    http://science.nhmccd.edu/biol/macmole.html

    http://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www2.nl.edu/jste/lipids.htmhttp://www.wisc-online.com/objects/index_tj.asp?objid=AP13204http://www.wisc-online.com/objects/index_tj.asp?objid=AP13204http://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://www.wisc-online.com/objects/index_tj.asp?objid=AP13204http://www.wisc-online.com/objects/index_tj.asp?objid=AP13204
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    MICRONUTRIENTS

    Used in small quantities Cannot be used for energy

    1. Vitamins

    Organic compounds that act as co-enzymes (activatean enzyme)

    Fat soluble vitamins A,D,E,K stored in fat tissues and are

    not excreted

    Toxic in large doses

    Water soluble vitamins B and C are not stored in body

    and excreted in the urine

    Large doses put strain on kidneys

    http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.html
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    2. Minerals

    Inorganic chemical elements

    Major minerals Required in higher doses

    Ca (bones), Mg, P (bones, ATP, DNA), K and Na

    Trace minerals

    Needed in minute amounts Includes Fe, Fl, Cu, Zn and more

    ALL DONE!!!!!

    http://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.htmlhttp://science.nhmccd.edu/biol/macmole.html