Blood transfusion

1. Bloodtransfusion

in the Netherlands and

in the LUMC

2. Haemovigilance

3. Quality indicators

4. Blood transfusion research

in Leiden

Blood in the Netherlands

500.000donors

Sanquin Products/components

distribution via

4 blood establishments

750.000components

Hospital bloodbanks

Central facility products apotheek

1.000.000

donations

Blood components

Component* Price Number

erythrocytes ≥ € 200 600.000

Platelets ≥ € 500 60.000

Plasma € 175 100.000

*NB about 100 products

Blood transfusion in the LUMC

-Dept of IHB : B of Bloodtransfusion- Section Blood Transfusion

- patient care : BTD*

- resesearch

* Blood Transfusion Dienst ( Service)

Personel Blood Transfusion Service 2009

Functie FTE ORD

Administratief medewerker 0.33

Analist 14.73 14.04

Arts assistent

Hemovigilantiemedewerker 0.25

Hoofdanalist 1.00

ICT 1.39

Klinisch chemicus

Kwaliteitsmedewerker 1.00

Medisch specialist 0.65

Hoogleraar sectiehoofd 1.00

Secretaresse 0.00

Senioranalist 1.84 1.21

Totaal FTE 22.19 15.25

Finances Blood Transfusion Service IHB

Financieën

29

7.0

00

36

5.0

00

35

7.0

00

1.3

18

.00

0

1.3

46

.00

0

6.3

14

.00

0

6.8

07

.00

0

6.2

09

.00

0

0

1.000.000

2.000.000

3.000.000

4.000.000

5.000.000

6.000.000

7.000.000

8.000.000

2007 2008 2009

jaar

euro

Bedrijfslasten

Personeelskosten

Waarde ingekochtebloedproducten

Haemovigilance in the hospital

• to transfuse or not to transfuse?• and if so: the right product to

the right patient.

Why Haemovigilance?

• to improve the quality of

- bloodproducts

- transfusion medicine

• to inform and educate the society

Transfusion safety > component safety

Dutch blood components are very safe

The risk of transfusion-transmitted infection is nearer to that of being struck by lightening than by being struck by a motor vehicle.

HBV 2 : 1.000.000

HCV 2 : 10.000.000

HIV 1 : 10.000.000

Hepatitis C virus RNA test

• introduced in UK in 1999 to detect infection missed by routine hepatitis C virus screening

• had detected one additional positive sample per 1.4 million donations tested, at a cost of £ 8.3 million per detection

• a suggested cost of £ 7.9 million per quality of life year gained is therefore almost certainly an underestimate

(McLelland and Contreras '05)

Risks of blood transfusion