Blood transfusion
1. Bloodtransfusion
in the Netherlands and
in the LUMC
2. Haemovigilance
3. Quality indicators
4. Blood transfusion research
in Leiden
Blood in the Netherlands
500.000donors
Sanquin Products/components
distribution via
4 blood establishments
750.000components
Hospital bloodbanks
Central facility products apotheek
1.000.000
donations
Blood components
Component* Price Number
erythrocytes ≥ € 200 600.000
Platelets ≥ € 500 60.000
Plasma € 175 100.000
*NB about 100 products
Blood transfusion in the LUMC
-Dept of IHB : B of Bloodtransfusion- Section Blood Transfusion
- patient care : BTD*
- resesearch
* Blood Transfusion Dienst ( Service)
Personel Blood Transfusion Service 2009
Functie FTE ORD
Administratief medewerker 0.33
Analist 14.73 14.04
Arts assistent
Hemovigilantiemedewerker 0.25
Hoofdanalist 1.00
ICT 1.39
Klinisch chemicus
Kwaliteitsmedewerker 1.00
Medisch specialist 0.65
Hoogleraar sectiehoofd 1.00
Secretaresse 0.00
Senioranalist 1.84 1.21
Totaal FTE 22.19 15.25
Finances Blood Transfusion Service IHB
Financieën
29
7.0
00
36
5.0
00
35
7.0
00
1.3
18
.00
0
1.3
46
.00
0
6.3
14
.00
0
6.8
07
.00
0
6.2
09
.00
0
0
1.000.000
2.000.000
3.000.000
4.000.000
5.000.000
6.000.000
7.000.000
8.000.000
2007 2008 2009
jaar
euro
Bedrijfslasten
Personeelskosten
Waarde ingekochtebloedproducten
Haemovigilance in the hospital
• to transfuse or not to transfuse?• and if so: the right product to
the right patient.
Why Haemovigilance?
• to improve the quality of
- bloodproducts
- transfusion medicine
• to inform and educate the society
Transfusion safety > component safety
Dutch blood components are very safe
The risk of transfusion-transmitted infection is nearer to that of being struck by lightening than by being struck by a motor vehicle.
HBV 2 : 1.000.000
HCV 2 : 10.000.000
HIV 1 : 10.000.000
Hepatitis C virus RNA test
• introduced in UK in 1999 to detect infection missed by routine hepatitis C virus screening
• had detected one additional positive sample per 1.4 million donations tested, at a cost of £ 8.3 million per detection
• a suggested cost of £ 7.9 million per quality of life year gained is therefore almost certainly an underestimate
(McLelland and Contreras '05)
Risks of blood transfusion