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BLUE-BRAIN Prejith S Roll No: 73 S 7 Dept. of A E& I Govt Engineering College, Kozhikode December 22, 2010 Prejith S () BLUE-BRAIN December 22, 2010 1 / 17

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Page 1: blue brain ppt

B L U E - B R A I N

Prejith SRoll No: 73

S7 Dept. of A E& IGovt Engineering College, Kozhikode

December 22, 2010

Prejith S () B L U E - B R A I N December 22, 2010 1 / 17

Page 2: blue brain ppt

Introduction B L U E - B R A I N

Introduction

Blue BrainIBM developing a virtualbrain known as Blue brain.With in 30 years, we will beable to scan ourselves intothe computers.

Virtual Brainan artificial brain.think, take decisions basedon the past experience, &respond as the natural braincan.

Why we need Virtual Brain?knowledge & intelligence ofanyone can be kept andused for ever.get assistance from amachine.

How it is possible?small robots, or Nanobots.Super computer.

Prejith S () B L U E - B R A I N December 22, 2010 2 / 17

Page 3: blue brain ppt

Introduction B L U E - B R A I N

Introduction

Blue BrainIBM developing a virtualbrain known as Blue brain.With in 30 years, we will beable to scan ourselves intothe computers.

Virtual Brainan artificial brain.think, take decisions basedon the past experience, &respond as the natural braincan.

Why we need Virtual Brain?knowledge & intelligence ofanyone can be kept andused for ever.get assistance from amachine.

How it is possible?small robots, or Nanobots.Super computer.

Prejith S () B L U E - B R A I N December 22, 2010 2 / 17

Page 4: blue brain ppt

Introduction B L U E - B R A I N

Introduction

Blue BrainIBM developing a virtualbrain known as Blue brain.With in 30 years, we will beable to scan ourselves intothe computers.

Virtual Brainan artificial brain.think, take decisions basedon the past experience, &respond as the natural braincan.

Why we need Virtual Brain?knowledge & intelligence ofanyone can be kept andused for ever.get assistance from amachine.

How it is possible?small robots, or Nanobots.Super computer.

Prejith S () B L U E - B R A I N December 22, 2010 2 / 17

Page 5: blue brain ppt

Introduction B L U E - B R A I N

Introduction

Blue BrainIBM developing a virtualbrain known as Blue brain.With in 30 years, we will beable to scan ourselves intothe computers.

Virtual Brainan artificial brain.think, take decisions basedon the past experience, &respond as the natural braincan.

Why we need Virtual Brain?knowledge & intelligence ofanyone can be kept andused for ever.get assistance from amachine.

How it is possible?small robots, or Nanobots.Super computer.

Prejith S () B L U E - B R A I N December 22, 2010 2 / 17

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Working of the Natural Brain. B L U E - B R A I N

Working of Natural Brain.

Human BrainInformation processing centrereceives signals from sensoryneuronsin response it generates andsends new signals that instructthe body to reactbrain weighs about 1,500 grams(3 pounds) and constitutesabout 2 percent of total bodyweightSensory InputIntegrationMotor Output

How we see, hear, feel, & smell?nose - olfactory bulb -olfactory tract - thalamus -smell sensory cortexlens - vitreous disc - - rods& cones - optic nerve - brainmicroscopic buds - sensorynerve fiber - braindrum - cochlea - corti -nerve- brain forinterpretation and memory.

Prejith S () B L U E - B R A I N December 22, 2010 3 / 17

Page 7: blue brain ppt

Working of the Natural Brain. B L U E - B R A I N

Working of Natural Brain.

Human BrainInformation processing centrereceives signals from sensoryneuronsin response it generates andsends new signals that instructthe body to reactbrain weighs about 1,500 grams(3 pounds) and constitutesabout 2 percent of total bodyweightSensory InputIntegrationMotor Output

How we see, hear, feel, & smell?nose - olfactory bulb -olfactory tract - thalamus -smell sensory cortexlens - vitreous disc - - rods& cones - optic nerve - brainmicroscopic buds - sensorynerve fiber - braindrum - cochlea - corti -nerve- brain forinterpretation and memory.

Prejith S () B L U E - B R A I N December 22, 2010 3 / 17

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Brain Simulation B L U E - B R A I N

Brain Simulation

Natural Brain Simulated BrainINPUT - sensory cells & neu-rons

INPUT - artificial neurons &sensory cells

INTERPRETATION - ac-complished by the meansof certain states of manyneurons

INTERPRETATION - bymeans of a set of register

OUTPUT - sensory cells &neurons

OUTPUT - artificial neurons& sensory cell

MEMORY - permanent stateneuron

MEMORY - registers can bestored permanently

PROCESSING - past experi-ence stored and the current in-put

PROCESSING - stored statesand the received input & byperforming some arithmeticand logical calculations.

Prejith S () B L U E - B R A I N December 22, 2010 4 / 17

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How the Blue Brain Projects work? B L U E - B R A I N

How the Blue Brain Projects work?

Goals & Objetives

Architecture of Blue Gene

Prejith S () B L U E - B R A I N December 22, 2010 5 / 17

Page 10: blue brain ppt

How the Blue Brain Projects work? B L U E - B R A I N

How the Blue Brain Projects work?

Goals & Objetives

Architecture of Blue Gene

Prejith S () B L U E - B R A I N December 22, 2010 5 / 17

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How the Blue Brain Projects work? B L U E - B R A I N

Modelling the Microcircuit

Prejith S () B L U E - B R A I N December 22, 2010 6 / 17

Page 12: blue brain ppt

How the Blue Brain Projects work? B L U E - B R A I N

Modelling the Microcircuit

Figure: Reconstructing the neocortical column

Prejith S () B L U E - B R A I N December 22, 2010 7 / 17

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How the Blue Brain Projects work? B L U E - B R A I N

Simulating the Microcircuitall the 8192 processors of the Blue Gene are pressed into servicea massively parallel computation solving the complexmathematical equations that govern the electrical activity in eachneuron when a stimulus is appliedthe results are communicated via interprocessor communicationtime required to simulate the circuit is about two orders ofmagnitude larger than the actual biological time simulatedThe Blue Brain team is working to streamline the computation sothat the circuit can function in real time

Prejith S () B L U E - B R A I N December 22, 2010 8 / 17

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How the Blue Brain Projects work? B L U E - B R A I N

Interpreting the ResultsBrain simulation generates huge amounts of dataanalyses dealing with the network activity must deal with datathat easily reaches hundreds of gigabytes per second of simulationArchitects at EPFL have worked with the Blue Brain developersto design a visualization interface that translates the Blue Genedata into a 3D visual representation of the columnvisualization of the neurons shapes is a challenging task given thefact that a column of 10,000 neurons rendered in high qualitymesh accounts for essentially 1 billion triangles for which about100GB of management data is requiredelectrical impulse travels through the column, neurons light upand change color as they become electrically activevisual interface makes it possible to quickly identify areas ofinterest that can then be studied more extensively using furthersimulations

Prejith S () B L U E - B R A I N December 22, 2010 9 / 17

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How the Blue Brain Projects work? B L U E - B R A I N

Whole Brain Simulations

Prejith S () B L U E - B R A I N December 22, 2010 10 / 17

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What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 17: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 18: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 19: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 20: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 21: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 22: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 23: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

What we can learn from Blue Brain?

Defining functions of the basic elements

Understanding complexity

Exploring the role of dendrites

Revealing functional diversity

Tracking the emergence of intelligence

Identifying points of vulnerability

Simulating disease and developing treatments

Providing a circuit design platform

Prejith S () B L U E - B R A I N December 22, 2010 11 / 17

Page 24: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 25: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 26: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 27: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 28: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 29: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 30: blue brain ppt

What we can learn from Blue Brain? B L U E - B R A I N

Applications of Blue Brain

Gathering and Testing 100 Years of Data

Cracking the Neural Code

Understanding Neocortical Information Processing

A Novel Tool for Drug Discovery for Brain Disorders

A Global Facility

A Foundation for Whole Brain Simulations

A Foundation for Molecular Modeling of Brain Function

Prejith S () B L U E - B R A I N December 22, 2010 12 / 17

Page 31: blue brain ppt

Advantages & Limitation B L U E - B R A I N

Advantages & Limitation

AdvantagesWe can remember thingswithout any effort.Decision can be made withoutthe presence of a person.Even after the death of a manhis intelligence can be used.The activity of differentanimals can be understood.It would allow the deaf to hearvia direct nerve stimulation,and also be helpful for curingmany psychological diseases.

LimitationsWe become dependent uponthe computer systems.Others may use technicalknowledge against us.Computer viruses will posean increasingly criticalthreat.The real threat, however, isthe fear that people willhave of new technologies.That fear may culminate ina large resistance.

Prejith S () B L U E - B R A I N December 22, 2010 13 / 17

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Advantages & Limitation B L U E - B R A I N

Advantages & Limitation

AdvantagesWe can remember thingswithout any effort.Decision can be made withoutthe presence of a person.Even after the death of a manhis intelligence can be used.The activity of differentanimals can be understood.It would allow the deaf to hearvia direct nerve stimulation,and also be helpful for curingmany psychological diseases.

LimitationsWe become dependent uponthe computer systems.Others may use technicalknowledge against us.Computer viruses will posean increasingly criticalthreat.The real threat, however, isthe fear that people willhave of new technologies.That fear may culminate ina large resistance.

Prejith S () B L U E - B R A I N December 22, 2010 13 / 17

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Conclusion B L U E - B R A I N

BLUE BRAIN

ConclusionWe can hope to learn a great deal about brain function anddisfunction from accurate models of the brain.Blue Brain will allow us to challenge the foundations of ourunderstanding of intelligence and generate new theories ofconsciousness.In conclusion, we will be able to transfer ourselves intocomputers at some point.

Prejith S () B L U E - B R A I N December 22, 2010 14 / 17

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References B L U E - B R A I N

References1 Henry Markram, “Engineering in Medicine and Biology Society,

2008. EMBS 2008. 30th Annual International Conference of theIEEE

2 Henry Markram, “The Blue Brain Project, Nature ReviewsNeuroscience 2006 February.

3 Simulated brain closer to thought BBC News 22 April 2009.4 Project Milestones. Blue Brain.

http://bluebrain.epfl.ch/Jahia/site/bluebrain/op/edit/pid/190855 Graham-Rowe, Duncan. Mission to build a simulated brain begins,

NewScientist, June 2005. pp. 1879-85.6 The Blue Brain Project: http://bluebrainproject.epfl.ch7 Blue Gene: http://www.research.ibm.com/bluegene

Prejith S () B L U E - B R A I N December 22, 2010 15 / 17

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BLUE BRAIN BLUE BRAIN

Prejith S () B L U E - B R A I N December 22, 2010 16 / 17

Page 36: blue brain ppt

BLUE BRAIN BLUE BRAIN

Prejith S () B L U E - B R A I N December 22, 2010 17 / 17