Business Trends

in Industrial Biotechnology

and its Organization in BRIC-Countries

Dr. Manfred Kircher Chairman of the Board

28.10. 2010

OECD; St. Petersburg

The German Chemical Industry

Nr. 3 in the world

Sales: 183 bio €

Employees: 400.000

Share in GDP (prod.ind.: 28 %

w/o constr.)

Currenta (Leverkusen)

in NRW:

Sales: 30 %

Employees 27 %

Petrochem. Production 74 %

Vegetable Oils

Animal Fats

Starch

Sugar

Cellulose

Fibres

Proteins

Rosin & Waxes

Other

Fossil Oil

72%

Natural Gas

14%

Coal

1%

BioRenewable

Feedstocks

13%

Germany 2008;

Chmie-Report VCI06/2010

The Need for Feedstock-Flexibility

is a Major Driver

K.Hill, R Höfer; Biomass for Green Chemistry;

in: R. Höfer (ed.) Sustainable Solutions for Modern

Economies; RSCPublishing (2009)

The Future of Industrial Biotechnology:

Combining Biotechnology & Chemistry

Biotechnology

Bioproduct

Endproduct

Bioproduct

Today

Tomorrow

Platform Chemical

Special Products

for Niche Markets

Platform Chemicals

for Bulk Markets Chemistry

BioProcess

PLA is an Example for Polymers

starting from Biotech-Monomers

OH

O

OH

O

O

O

O

O

O

OH

HO

CH3

CH3

CH3

O

O

On

L-lactic

acid

L,L-lactide

D,L-lactide

D,D-lactide

Sugar Poly-lactide

PLA

Chemical Polymerization

Catalyst

Heat

Biomass-

Processing

BioPlatform Chemicals

on the Way to Commodities

1,3 PDO Dupont 50.000 t/a operating

PHA ADM 50.000 t/a

Butanol Shi Jinyan 50.000 t/a

PE ex EtOH Braskem 200.000 t/a

L-Lactic Acid Purac 100.000 t/a under

construction

Succinic Acid BASF

BioAmber pilot scale

Myriant

Farnesen Amyris

Acrylic Acid Novozyme

Methylmethacrylate Evonik Degussa

BDO/THF Tate&Lyle/Genomatika R&D

Isopren Goodyear/Genencor

Caprolactam DSM

Source: Oskar Zelder; 8.7.2010; BMBF; Berlin

EuropaBio:

20 % Biobased Products by 2020

0 5 10 15 20 25 30 35 40 45 50 Source: VCI 2009

Polymers

Pharmaceuticals

Fine & Special Chemistry

Petrochemicals & Derivatives

Detergents & Hygienic Chemicals

Inorganics

: Biotech. Products 2009 : Biotech. Products 2021

Ch

em

ica

l I

nd

us

try S

ale

s

(Ge

rma

ny; € b

io)

2020: 20%

2009: 6%

Chemical Sales

Today Industrial Biotechnonology is

Based on Agricultural Sugar Sources

+ aerob fractionation

30%

70% of Biomass Carbon

Wheat

Sugar beet

Corn

Sugar cane Sugar beet

BioEnergy Industries

will Dominate the Sugar Markets

EU

USA

BRA

0

50

2004 2005 2006 2007 2008

Bioethanol-Plant Pischelsdorf

2004 2005 2006 2007 2008

40

30

20

10

0

50

Bioethanol Production

[mio m³]

Germany:

Bioethanol Consumption 2008-2009 +61%

Non-Food Lignocellulose

might be an Alternative

Partnering reduces the technical and financial risk

Partnering improves meeting an important need

The CLIB-Model for Innovation

is Partnering

Partnering guides to the open market space

Partnering watches emerging technologies better

Partnering shortens time to market

Sugarbeet

Corn

Seed

Value

Plant-

Biomass

Pharma-

Active

Polyester

Amino Acid

Adhesive Protein

Succinate

Sphingosine

Plastics

Feedstock-Industry

(Bio-)Chemical Industry

Consumer Industries

Cosmetics

Bottle

Lignocellulose

Syngas

CO, CO2, H2

Sugar 1,4-Butandiol

Isoprene

Rubber

Tire

Starch

Sugar

Polyisoprene

L-tert.-Leucine

Pharmaceuticals

Value-Chain

Dermatolog.

Active

Agriculture

CLIB2021 Links All Stakeholders

and Shortens Time to Market

EU-Report

presents CLIB2021 as a model

India: Leading in Vaccine Production

Cooperation in Protein-Technologies

Academia: application oriented

BioIndustry: protein production

service provider

Feedstocks: to be developed

China: Catching up in Science

Leading Bulk Producer

Academia: catching up very fast

BioIndustry: leading in bulk production

needs to move towards bioeconomy

Feedstocks: to be developed

Europe will Depend on Import

of Renewable Carbon Sources

5 5

300 5

30

20

85

20

35

Expected Biomass Trade Routes by 2020 [TWh] Source: The Future of Industrial Biorefineries; World Economic Forum, 2010

:Plant-Oil

:Biomass

10

15

10

Brazil is Blessed

with Sugar & Lignocellulose

0%

5%

10%

15%

20%

[Sh

are

of

Wo

rld

Su

ga

r]

Brazil EU India China USA

19%

of World Sugar Production

Brazil: The Global Leader

in BioChemical Precursors ?

Academia: focus on sugar transformation

BioIndustry: ethanol > biochemicals

Feedstocks: global leader in sugar cane

Russia is Blessed with Starch

and Lignocellulosic Carbon Sources

0

200.000

400.000

600.000

800.000

1.000.000

[10

00

ha

]

Russia Brazil Canada USA China

22%

of Global Forest Area

30.9.2010: CLIB-Office in Russia

Cooperation in Science & Business

Academia: broad tradition in scientific excellence

BioIndustry: 1985: 5 % world market share

2010: 0,2 % „

Feedstocks: leading in wheat & lignocellulose

ERA-Net to be Prolonged by 5 Years

Russia may be Partner!

16.11.2010

Next Meeting in Dresden

CLIB2021 Cluster Industrielle Biotechnologie e.V.

CLIB2021

Partnering Excellence

in Science, Production

and Commercialization

is Key to Success