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Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology VA Eastern Colorado Health Care System Associate Professor of Medicine University of Colorado, Denver

Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

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Page 1: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case-Based Practical ECG Interpretation for the Generalist

Paul D. Varosy, MD, FACC, FAHA, FHRSDirector of Cardiac Electrophysiology

VA Eastern Colorado Health Care System

Associate Professor of Medicine

University of Colorado, Denver

Page 2: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Disclosures

None

Page 3: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Overview

ECG Basics – Methodological Approach to Reading ECGs

Differentiation of Supraventricular Arrhythmias

SVT classification

Atrial Fibrillation vs. Atrial Flutter

WPW Syndrome

Recognition and management of a long QT interval

Review

Page 4: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 5: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 6: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 7: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

Page 8: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

Page 9: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

II

Page 10: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

II III

Page 11: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

II III

aVR

Page 12: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

II III

aVRaVL

Page 13: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

II III

aVRaVL

aVF

Page 14: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

RA LA

LL

I

II III

aVRaVL

aVF

Einthoven’s Triangle

Page 15: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 16: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 17: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 18: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

The Modern 12-Lead ECG

Page 19: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

The Modern 12-Lead ECG

One of the quintessential tools of Cardiology

Page 20: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Approach to the 12-Lead ECG

Rate

Rhythm

Intervals

Axis

QRS Morphology (Infarction, Hypertrophy)

ST Segment and T Waves

Page 21: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Measuring ECG Intervals

At 25 mm/sec paper speed:

Large boxes are 0.2 sec (200 msec)Small boxes are 0.04 sec (40 msec)

Page 22: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 23: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 24: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 25: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 26: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 27: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Supraventricular Tachycardia (SVT)

SVT is commonPrevalence of ~1/500

Incidence of ~90,000 new cases per year

AVNRT accounts for 50-60% of all SVT

Dual AV Node PhysiologyPresent in as many as 30-40%

Only a small percentage have clinical SVT

Page 28: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

SVT: Differential Diagnosis

Sinus tachycardia

Atrial tachycardia

Atrial flutter

Atrioventricular nodal reentrant tachycardia (AVNRT)

Orthodromic atrioventricular reentrant tachycardia (AVRT)

Junctional tachycardia

Paroxysmal form of junctional reciprocating tachycardia (PJRT)

Page 29: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Subcategorizing SVT: P wave

No P or P-in-QRS

Short RP

Long RP

Page 30: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Subcategorizing SVT: P wave

No P or P-in-QRS

Short RP

Long RP

Helps to focus the differential diagnosis!!

Page 31: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

No P or P in QRS

R R

Page 32: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

No P or P in QRS

Differential diagnosis:AVNRT

Atrial flutter

AT with 1st degree AV block

JT

Much less likely AVRT

Page 33: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 34: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 35: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

AVNRT: Atrioventricular Nodal Reentrant Tachycardia

Page 36: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Short RP

R RP

RP interval

Page 37: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Short RP

Differential diagnosis:AVRT

AVNRT

AT with 1st degree AV conduction delay

JT

Page 38: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 39: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 40: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

AVRT: Atrioventricular Reentrant Tachycardia

• .

Page 41: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Long RP

R RP

RP interval

Page 42: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Long RP

Differential diagnosis:Sinus tachycardia

Atrial tachycardia

AVNRT (atypical form)

Junctional tachycardia

AVRT

Page 43: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 44: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Atrial Tachycardia

Focal arrhythmia arising in either right or left atrium

Several arrhythmia mechanisms are possibleAutomatic

Triggered

Micro-reentrant

Most common site is the right atrial crista terminalis near the sinus node

Page 45: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 46: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Differentiating Atrial Fibrillation from Flutter

Atrial Fibrillation

• Disorganized atrial activity

• Irregularly-irregular ventricular response

Atrial Flutter

• Organized atrial activity – intra-atrial macro-reentry

• Often regular rapid ventricular response (2:1 conduction ~150 bpm)

Page 47: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Differentiating Atrial Fibrillation from Flutter

Atrial Fibrillation

• Rate control generally possible

• Ablation is sometimes successful (improves symptoms in 50-60%)

• Moderate risk of complications (5-10%)

Atrial Flutter

• Rate is difficult to control

• Ablation is highly successful (>95% cure)

• Ablation is low risk (<2%)

Page 48: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 49: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 50: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 51: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 52: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 53: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 1

30 yo man awoke on a Saturday morning with sudden onset palpitations, dyspnea, and presyncope.

This episode followed an evening of drinking substantially more than usual with friends.

No known medical problems.

Came to the ED for medical attention.

Page 54: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 55: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 56: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 1

30 yo man awakened with palpitations, dyspnea, and presyncope

Tachycardic, irregular, but otherwise normal exam

Abnormal ECG

Normal Echocardiogram

Page 57: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 1

30 yo man awakened with palpitations, dyspnea, and presyncope

Wolff-Parkinson-White Syndrome

with preexcited atrial fibrillation

Page 58: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Accessory Pathway

Page 59: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Wolff-Parkinson-White Syndrome

Sinus ECG shows evidence of pre-excitation

Typical episodes of tachycardiaOrthodromic AVRT

Antidromic AVRT

SVT with pre-excitation (most commonly atrial fibrillation with pre-excitation)

Page 60: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Tachycardias with Accessory Pathways

Atrioventricular Reentrant Tachycardia (AVRT)A reentrant arrhythmia involving

AtriumAV Node/His-Purkinje systemVentricleAccessory Pathway

Orthodromic: down the conduction system(Narrow complex)

Antidromic: up the conduction system(Wide complex)

SVT with pre-excitation

Page 61: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 62: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 63: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Treatment of Accessory Pathway-Mediated TachycardiasMedical:

AVRT:AV nodal blockers (adenosine, etc)

Atrial fibrillation with pre-excitation:NO AV BLOCKERS: Risk of V Fib!!!

Procainamide – slows conduction in pathway

Electrical: cardioversion if unstable

Radiofrequency ablationAlmost always curative!

Page 64: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 65: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 66: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 1

30 yo man awakened with palpitations, dyspnea, and presyncope

Underwent successful RF catheter ablation

of a posteroseptal accessory pathway

Page 67: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 68: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 2

60 yo man with multiple episodes of syncope, all occurring in the setting of urination.

Katz JAMA Internal Med 2013;173:1543-1544

Page 69: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 2

60 yo man with multiple episodes of syncope, all occurring in the setting of urination.

He has a history of IV drug use currently in remission on methadone therapy.

Katz JAMA Internal Med 2013;173:1543-1544

Page 70: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 71: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

ECG Recognition of a prolonged QT Interval

All 12 leads can be used, V2 and V3 may be best to exclude U waves

Rule of thumb: If the QT interval is more than half the RR, it’s probably too long

QT correction – several approaches to account for changes with HR

Bazett QTc = 𝑄𝑇

𝑅𝑅

Fridericia

Nomogram

Page 72: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 73: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Acquired Long QT

Prolonged QTc found in up to 1% of hospitalized patients

Risk Factors:Electrolyte disturbances (K, Mg, Ca)

Hypothyroidism

Anorexia

Bradycardia

Structural heart issues (LVH, reduced LVEF)

Medications (antiarrhythmics, psychotropic drugs, antibiotics, etc.)

Page 74: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

www.crediblemeds.org

Page 75: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Case 3

19 yo woman with palpitations and lightheadedness. Her mother died suddenly at age 25.

Page 76: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

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Page 77: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

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Page 78: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Congenital Long QT Syndrome

Much less common than acquired QT prolongation – 1/2000

Clinical syndromes:Romano-Ward (Autosomal dominant, cardiac only)

Jervell and Lange-Nielsen (Autosomal recessive, sensorineural deafness)

300+ mutations in ~20 genes identified

PhenotypesLQT1 – events with exercise (especially swimming) (35%)

LQT2 – events with auditory stimuli (25%)

LQT2 and LQT3 – events during sleep (10%)

Page 79: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 80: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Please see slide at presentation

Page 81: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

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Page 82: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

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Page 83: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Congenital Long QT Syndrome - Management

Avoid exacerbating factors (medications, etc.)

Beta Blockers (especially LQT1) – propranolol, nadolol preferred

Pacing and/or ICD if symptoms/events on beta blocker

Sports – debate about restriction

Page 84: Case-Based Practical ECG Interpretation for the Generalist · Case-Based Practical ECG Interpretation for the Generalist Paul D. Varosy, MD, FACC, FAHA, FHRS Director of Cardiac Electrophysiology

Review

ECG Basics – Methodological Approach to Reading ECGs

Differentiation of Supraventricular Arrhythmias

SVT classification

Atrial Fibrillation vs. Atrial Flutter

WPW Syndrome

Recognition and management of a long QT interval

Review