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8/12/2019 cefoxitin and ketorolac edited!!.docx
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DRUG STUDY
Patient : Palao, Apple Age: 19
Diagnosis: open cholecystectomy Admission date: January 24, 2014
GenericName(BrandName)
Dosage andFrequency
Action Classification
Indication Contraindication
Adversereaction
Nursing Responsibilities
Genericname:Cefoxitin
Brandname:Mefoxin
Dosage:
IMIV(Adults)1-2g (6-8hr)(Infants)80-160mg/kg/dayIM
&IV dividedoses q 4-6hr. Do notexceed12g/day
Prescribed1g, TIV,1hour prior toOR and Q6was given to
the client.
Bactericidal:Inhibitssynthesisof bacterial cellwall, causingcell death.
Antibiotic Perioperativeprophylaxis,intra- abdominalinfections
Contraindicatedwith allergy tocephalosporins
or penicillins.Use cautiouslywith renal failure,lactation, pregna
ncy
CNS:headache,dizziness,lethargy, parasthesisGI: Nausea,vomitting,diarrhea,
anorexia,abdominal pain,flatulenceGU: NephrotoxicityHEMATOLOGIC: Bone marrows,depressions,decreased WBC,decreasedplatelets,
deacreased Hct.LOCAL
: Pain, abscess atinjections site,inflammation at IVsite
Inform patient to Avoid alcoholwhile taking this drug andfor 3days after because severereactions often occur. You mayexperience these side effects:stomach upset, diarrhea.Report severe diarrhea,
difficulty breathing, unusualtiredness or fatigue, pain atinjection site
Inform the patient that he/shehas the right to refuse therapyprovided that she sign a waiver
Evaluate patient response totherapy/ medication
Document date, time, ofadmission
Assess for sensitivity test ofthe patient to drug
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GenericName:Ketorolac
Brand
name:Toradol
30mg, IM/IV,to amaximum of120mg/day
Prescribed:Dosage:30mgFrequency:
Q6Route:
IVT
Inhibitsprostaglandinsynthesis bydecreasing theactivity of the
enzyme,cyclooxygenase,which results indecreasedformation ofprostaglandinprecursors,chemicals thatcellsof the immune
system makethatcause theredness,fever, and painofinflammationandthat also arebelieved to beimportant in the
production ofnoninflammatorypain.
Nonsteroidal
Anti-inflammatory
Drugs(NSAIDs)
Non opiodanalgesics
Short termmanagement ofpain ( up o 5days)
Hypersensitivityto ketorolac,aspirin, otherNSAIDs, or anycomponent
of theformulation;patients whohave developednasal polyps,angioedema, orbronchospasticreactions toother NSAIDs;active orhistory of peptic
ulcerdisease; recentor history ofGI bleeding orperforation;patients withadvanced renaldisease or risk ofrenalfailure; labor anddelivery;
nursing mothers;prophylaxisbefore majorsurgery.
Rash
Ringing in theears
Headaches
Dizziness
Drowsiness
Abdominal
Pain
Nausea
Diarrhea
Constipation
Heartburn
FluidRetention
Assess for rhinitis, asthma, andurticaria.
Assess pain (note type,location, and intensity) prior toand 1-2 hr following
administration.Ketorolac therapy should
always be given initially by theIM or IV route.
Inform patient to avoidconcurrent use of alcohol,aspirin, NSAIDs,acetaminophen, or other OTCmedications without consultinghealth care professional.
Advise patient to consult if
rash, itching, visualdisturbances, tinnitus, weightgain, edema, black stools,persistent headche, orinfluenza-like syndromes(chills,fever,muscles aches,pain) occur.
Effectiveness of therapy can bedemonstrated by decrease inseverity of pain. Patients whodo not respond to one NSAIDs
may respond to another.Inform the patient that she has
the right to refuse therapy/medication provided that shesign the waiver
Evaluate patient response tomedicine after 30 minutes.
Document date and time of timeof admission
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