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Chapter 10: The Endocrine System © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill

Chapter 10: The Endocrine System © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill

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Page 1: Chapter 10: The Endocrine System © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill

Chapter 10: The Endocrine System

© 2013 by The McGraw-Hill Companies, Inc. All rights reserved.

McGraw-Hill

Page 2: Chapter 10: The Endocrine System © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill

McGraw-Hill

Learning Outcomes

10-2

Recall the parts/function of endocrine systemDefine combining forms used in building

words that relate to the endocrine system.Recall the common diagnoses, laboratory

tests, and clinical procedures used in treating disorders of the endocrine system.

Define the major pathological conditions of the endocrine system.

Define surgical terms related to the endocrine system.

Recognize common pharmacological agents used in treating disorders of the endocrine system.

Page 3: Chapter 10: The Endocrine System © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill

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Structure/ FunctionGroup of glands act as body’s master

regulator of chemicals that affect the entire body

Hormones secretion

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Endocrine System

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Secretions and FunctionsHypothalamuspituitary-regulating hormones ,either

stimulate or inhibit pituitary secretionsNeurohypophysis  antidiuretic hormone (ADH), vasopressin

oxytocin ,melanocyte-stimulating hormone (MSH),increase water reabsorption ,stimulates uterine contractions and lactation ,stimulates the production of melanin

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Secretions and FunctionsAdenohypophysisGrowth, somatotrophic, thyroid-stimulating,

adrenocortictropic, follicle-stimulating, and luteinizing and prolactin hormones

bone and muscle growth; regulate metabolic functions, stimulates thyroid gland, stimulates adrenal cortex development of ova and production of female hormones, breast development and milk production

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Secretions and FunctionsThyroidthyroxine ; triiodothyronine , calcitonin,regulates metabolism; stimulates growth,

lowers blood calcium as necessary to maintain

homeostasisParathyroid parathormone, parathyroid hormone

(PTH), increase blood calcium as necessary to maintain homeostasis

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Secretions and FunctionsAdrenal MedullaEpinephrine and norepinephrine  React to stressAdrenal Cortexglucocorticoids , mineralocorticoids ,

gonadocorticoids  affect metabolism, growth, and aid in

electrolyte and fluid balances

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Secretions and FunctionsPancreas insulin, glucagons, maintains blood glucose

concentrationPineal Gland Melatonin, affects sexual functions and sleep

cycles

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Secretions and Functions OvariesEstrogen and progesterone, female sex

characteristics, menstrual cycle, reproductive functions

Testes Androgen, testosterone, male sex

characteristics, sperm production

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Secretions and FunctionsThymus gland thymosin, thymic humoral factor , factor

thymic serum , T cells and some B cells development; function not well understood

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Combining Forms aden(o) glandadren(o), adrenal(o) adrenal

glandsgluc(o) glucoseglyc(o) glycogengonad(o) sex glandspancreat(o) pancreasparathyroid(o) parathyroidthyr(o), thyroid(o) thyroid

gland

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Hypothalamus/Pituitary

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Hypothalamus, Pineal, Pituitary Gland Hypothalamus = stimulates / inhibits

secretionsPineal gland = sexual function / sleep cyclesPituitary gland = growth and metabolism

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Thyroid ,Parathyroid, Thymus, AdrenalThyroid affects= metabolismThymus gland = aids in T and B cellsAdrenal glands= metabolism, growth, fluid

and electrolyte balance

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Thyroid gland

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Parathyroid glands

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Adrenal glands

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Pancreas, Ovaries, TestesPancreas = insulin = maintain glucose levels Ovaries= estrogen and progesterone Testes = testosterone

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Pancreas

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Diagnostic, Procedural, Lab TermAssist in diagnosing medical conditionsOften used in combination, Lead to a final diagnosis and treatment

planning

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Programmed Reviewfasting blood sugarglucose tolerance

test (GTT)blood sugarblood glucose

postprandialblood sugarurine sugarglycated hemoglobin

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Pathological TermsDisorders of the pituitary, thyroid,

parathyroid and adrenal glands can affect many functions within the body.

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Cretinism

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Grave’s disease

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Iodine Deficiency

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Pancreas DisordersPancreatic disorders frequently lead to

diabetes. Diabetes can impact many other systems

within the body. pancreatitishypoglycemiadiabetes mellitusdiabetes

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Pancreas Disorders (cont.)Type I diabetes

(insulin-dependent diabetes mellitus or IDDM)

Type II diabetes(non insulin dependent diabetes mellitus or NIDDM)

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Pancreas Disorders (cont.)glucosuriadiabetic

nephropathydiabetic neuropathy

diabetic retinopathyacidosisketoacidosisketosis

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Endocrine System and CancerCancers occur commonly in the endocrine

systemThyroid cancer= remove gland +replace

hormonePancreatic cancer= fatal = No good

treatments

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Surgical TermsEndocrine glands that become diseased can

be surgically removed. Synthetic hormones replacementadenectomyadrenalectomyhypophysectomy

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Surgical Terms (cont.) pancreatectomyparathyroidectomythymectomyThyroidectomyhormone replacement therapy (HRT)antiphypoglycemicantihyperglycemic

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Surgical Terms (cont.)hypoglycemichuman growth hormonesteroidsradioactive iodine therapy

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Page 34: Chapter 10: The Endocrine System © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill

McGraw-Hill

Chapter ReviewRecall the parts/function of endocrine systemDefine combining forms used in building words

that relate to the endocrine system.Recall the common diagnoses, laboratory tests,

and clinical procedures used in treating disorders of the endocrine system.

Define the major pathological conditions of the endocrine system.

Define surgical terms related to the endocrine system.

Recognize common pharmacological agents used in treating disorders of the endocrine system.

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