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Chapter 11 (part 2) Regulation of Glycolysis

Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

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Page 1: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Chapter 11 (part 2)

Regulation of Glycolysis

Page 2: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation
Page 3: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Lactate formation

  

H3C C C

OO

O

NADH NAD

NADH NAD

H3C CH

C

OHO

O

Page 4: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Cori Cycle

Page 5: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Alcohol Fermentation

Page 6: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Free Energy Change in Glycolysis

HexokinasePhosphofructokinase-1

Pyruvate kinase

Page 7: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Control Points in Glycolysis

Page 8: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Insulin Induced Exocytosis of Glucose Transporter

Page 9: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Effect of ATP on PFK-1 Activity

Page 10: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Effect of ADP and AMP on PFK-1 Activity

Page 11: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Regulation of PFK by Fructose-2,6-bisphosphate

Page 12: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Glucagon Regulation of PFK-1 in Liver

Page 13: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Pyruvate Kinase Regulation

Page 14: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

Other Sugars can

enter glycolysis

Page 15: Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation

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