Carboxylic amidesQ 0490 DOI: 10.1002/chin.201238060

Synthesis and Fungicidal Activity of New Fluorine-Containing Mandelic Acid Amide Compounds. — A series of title compounds is synthesized in which the methyl group of catecholamine is replaced by a trifluoromethyl moiety. The fungicidal activity of the novel compounds has close relation to the degree of unsaturation of the substi-tuent introduced in the trifluoromethoxyphenyl moiety. Compounds possessing either benzyl or propargyl at this position, cf. (XId), (XIe), and (XIII) have good fungicidal activities against P.cubensis, whereas compounds (XIa)—(XIc) are inactive. — (LI, S.; CUI, C.; WANG, M.-Y.; YU, S.-J.; SHI, Y.-X.; ZHANG, X.; LI, Z.-M.; ZHAO*, W.-G.; LI, B.-J.; J. Fluorine Chem. 137 (2012) 108-112, http://dx.doi.org/10.1016/j.jfluchem.2012.02.011 ; State Key Lab. Elem.-Org. Chem., Nankai Univ., Tianjin 300071, Peop. Rep. China; Eng.) — H. Hoennerscheid

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ChemInform 2012, 43, issue 01 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim