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Child and Adolescent Psychiatry & Mind-body Approaches in Traditional Chinese Medicine : Suggestions over Treatments and Prevention What Occidental Psychiatry can learn about Traditional Chinese Medicine ? Dr Marie Ducloy, Child and Adolescent Psychiatrist 30/11/2017

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  • Child and Adolescent Psychiatry& Mind-body Approachesin Traditional Chinese Medicine : Suggestions over Treatments and PreventionWhat Occidental Psychiatry can learn about Traditional Chinese Medicine ?

    Dr Marie Ducloy, Child and Adolescent Psychiatrist

    30/11/2017

  • Acknowlegment

    •  Thanks to

    •  Pr Baumelou,

    •  Dr Bingkai Liu

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • About me [1]

    •  Child and Adolescent Psychiatrist :

    •  in medical office in Paris

    •  Attached Practitioner in Sainte-Anne Psychiatric Hospital in Paris : research field/Virtual Medicine

    •  DUPRAC (2016-2017), DUMETRAC (2017-2018), La Pitié University

    •  Hospital works : Sainte-Anne hospital, Robert Debré hospital

    •  Research works : Pasteur Institute

    •  Personal practicing in meditation and yoga

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • On-going work

    •  Present work during last year

    •  Extract from a manuscript

    •  Using Medical Research criteria,

    •  Medical Literature systematic Review

    •  Not a conclusive study or document, but on-going work

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • Table of content

    •  1. Health and Disease over Occidental Medicine and Traditional Chinese Medicine

    •  2. Child development in Child and Adolescent Psychiatry and Traditional Chinese Medicine

    •  3. Main Child and Adolescent psychiatric troubles

    •  4. Diagnosis over Child and Adolescent Psychiatry and TCM

    •  5. Evidence-based Medicine and Mind-body approaches in TCM

    •  6. Discussion, Conclusion

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • 1. Health and disease

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • •  Health [2] :

    •  a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.

    •  But Occidental Medicine defines disease first

    •  Hippocratis (460-370 BC) :

    •  defines disease instead of health

    •  Time considered as linear

    1. Health and Disease in Occidental Medicine (OM)

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    Organ as basic unit, Disease due to organic damage,

    but lack of brain knowledge

  • 1. Health and Disease in Traditional Chinese Medicine (TCM)•  ⻩黄帝内经 Huangdi Neijing [3] :

    •  during Han dynasty (206 BC-220 AD)

    •  Health as natural inner and outer balance [4]

    •  道德經 Daodejing [5] : ⽼老老⼦子 Laozi (200 BC)

    •  origins of 道 Dao

    •  Time considered as circular

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    氣 Qi as basic element, Diseases due to Qi imbalance

  • 1. Child and Adolescent Psychiatry and TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    Interest of TCM Mind-body approaches in Child and Adolescent Psychiatry ?

    •  Traditional Chinese Medicine :

    •  Use of Traditional Pharmacology

    •  Use of Mind-Body approaches

    •  Child and Adolescent Psychiatry :

    •  Recent Occidental Medicine issue (1929-1945) [6]

    •  Use of limited Pharmacology

    •  Use of Psychological approaches

    •  Use of few Mind-Body approaches

  • 2. Child development

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  From in utero to birth :

    2. Child development : Embryology

    Sensory organs development [7]

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    2. Child development in Child and Adolescent Psychiatry

    Sensorimotor development

    [8]

    Fine Motor skills

    Global Motor skills

    Langage

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    2. Child development in Child and Adolescent Psychiatry

    Emotional development : Attachement

    theory[9]

    Reactions to emotional

    needs

    Inner emotional security /

    Possibility to explore

    Inner emotional insecurity / Symptoms

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    2. Child development in Child and Adolescent Psychiatry

    Cognitive development

    [10]

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    2. Child development in Child and Adolescent Psychiatry

    Social development

    [11]

    Social interactions

    Non-verbal communication

    Verbal communication

    Behaviors

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    2. Child development in Child and Adolescent Psychiatry

    Emotional development : Attachement

    theory

    Cognitive development

    Social development

    [9]

    [10]

    [11]

    Sensorimotor development

    [8]

  • Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    2. Child 氣 Qi developmentin TCM

    Progressive process

  • 3. Main Child and Adolescent psychiatric troubles

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • 3. Main Child and Adolescent psychiatric troubles

    •  Autism Spectrum Disorders [12]:

    •  Impairement in social communication

    •  Restricted and repetitive patterns of behavior, interests

    •  during early childhood

    •  clinically significant

    •  frequently associated with physical and genetic troubles

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  TCM : 五迟 Wu Chi as developmental delay including [13] :

    •  ⽴立迟 Li Chi : motor developmental delay,

    •  ⾏行行迟 Xing Chi : intellectual delay

    •  语迟 Yu Chi : langage delay

    •  some Sp like ASD

  • 3. Main Child and Adolescent psychiatric troubles

    •  Attention Deficit Hyperactivity Disorder [14]:

    •  Impulsivity

    •  Attention deficit

    •  +/- Hyperactivity

    •  frequently associated with somatic and genetic troubles

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  TCM : No equivalent

    •  Possible Blader fire

    •  Yin-Yang Dysharmony

    •  Heart-Kidney defect [15]

  • 3. Main Child and Adolescent psychiatric troubles

    •  Disruptive Mood Dysregulation Disorder [16]:

    •  Important and durable Sadness or Anger

    •  Insomnia

    •  Hyperresponsiveness

    •  Tachypsychia

    •  Before 12 yo

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  TCM : Emotions dysregulation [17] :

    •  喜 xi excess : Happiness excess from Heart

    •  怒怒 nù : Anger from Liver fire

    •  悲 béi : Sadness from Lung

    •  Zheng phenotype : depression

  • 3. Main Child and Adolescent psychiatric troubles

    •  Anxiety, Body complains [18]:

    •  Specific phobia

    •  Obsessive Compulsive Disorder

    •  Headache, Stomach/Back Pain

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  TCM :

    •  恐 kông : Fear from Kidney

  • 4. Diagnosis over Child and Adolescent Psychiatry and TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • 4. Diagnosis over Child and Adolescent Psychiatry and TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Psychiatric inventory :

    •  Interview

    •  Examination

    •  Maybe neurologic exam

    •  Specific tests

    •  TCM :

    •  神 Shen Observation

    •  Pulse

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Using Medical Research approach, Literature review

    •  PubMed :

    •  "Traditional Chinese Medicine” : 30 533 articles

    •  “Traditional Chinese Medicine" AND “Psychiatry" : 203 articles

    •  "Traditional Chinese Medicine" AND “Children" : 314 articles

    Evolution of article numbers about TCM on PubMed per year

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Meditation on Child and Adolescent population [19]:

    •  Attention regulation

    •  Emotional and mood regulation

    •  Well-being

    •  Depressive Sp,

    •  Anxiety, Pain

    For schools, patients and parents

    How ?

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Meditation on Child and Adolescent population [20,21,22]:

    How ?

    Decreased Amygdale activity

    Decreased Inner and Medial Brain Structure activity

    Decreased Pre-Frontal Cortex activity

    Decreased insula and singula activity

  • Interaction between meditation and pain-related brain activation in MRI session.

    General linear modeling analyses detected a significant interaction in SI (z=68) between

    meditation and rest in the presence of noxious stimulation. There was a significant activation of the contra lateral SI during heat stimulation while

    subjects were not meditating. Meditation significantly reduced activation in SI during noxious

    heat stimulation. Slice locations correspond to standard stereotaxic space.

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    5. Evidence-based Medicine and Mind-body approaches in TCM

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Tuina Massage in Child and Adolescent population [23]:

    •  Weight increase in Anorexia Nervosa

    •  Pain and Body complains

    •  Needs to be continuous to be effective

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Acupuncture [24]:

    Biological

    effects ?

    •  Qi regulation

    •  Anxiety, Pain

    •  Depression

  • 5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Acupuncture :

    Biological

    issues ?

    MEK1 in hypothalamus and hippocampus

    (ERK)-cAMP-(CREB) signalling modification

    NO, PGE2, iNOS, COX-2, NF-kB, IL-1, IL-6 in hippocampus and PFC

    Primary motor cortex activation

    Interhemispheric inhibition

  • •  Attention regulation

    •  Emotional regulation

    •  Sleep disorder

    •  Anxiety, Pain

    5. Evidence-based Medicine and Mind-body approaches in TCM

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

    •  Taiji Quan in Child and Adolescent population [25]:

    •  Qi Gong in Child and Adolescent population [26]:

    •  Autistic Sp

    •  Self-regulation in ASD

    •  Chronic Headache

  • 6. Discussion, Conclusion

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • 6. Discussion, Conclusion

    •  TCM and Child and Adolescent Psychiatry : interest in global care

    •  Lack of Body-Mind Approaches in Child and Adolescent Psychiatry

    •  No use of Mind-body TCM treatments in Child and Adolescent Psychiatry today

    •  Complementarity of Mind-Body TCM

    •  New prevention and treatment perspectives

    •  And if we (OM) can learn about TCM, maybe TCM can also learn from us

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017

  • The usefulness of a pot comes from its emptiness.Laozi ⽼老老⼦子 , Daodejing 道德經

    Thank you for your attention.

    Dr Marie [email protected]

    Child and Adolescent Psychiatry & TCM : Suggestions over Treatments and Prevention, Dr Ducloy, 30/11/2017