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PLAGUES IN MAN CHOLERA

CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

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Page 1: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PLAGUES IN MAN

CHOLERA

Page 2: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

John Snow & his famous map (1854)

Page 3: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Page 4: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Vibrio cholera

1 X 4 µm

Bent rods: “comma bacillus”

With polar flagella

The Agent

Page 5: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

The Agent

Page 6: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Transmission

Page 7: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Transmission

Page 8: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Colonization

Page 9: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Colonization

Attachment fimbriae

Page 10: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

ToxinosisSTRUCTURE OF TOXIN

Page 11: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

ToxinosisACTION OF TOXIN

Page 12: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

SYMPTOMS

Page 13: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PREVENTION & TREATMENTComposition of an E. coli cell

Page 14: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PREVENTION & TREATMENT

Page 15: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PREVENTION & TREATMENT

Page 16: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PREVENTION & TREATMENT

Page 17: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PANDEMICS

The seventh (current)

Page 18: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PANDEMICS

The seventh (current)

Page 19: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PANDEMICS

History

King Cholera

Page 20: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Pandemics

History

Cholera posters - 1831 The 2nd Pandemic

Page 21: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

PandemicsHistory

Jonh Snow’s map The 3rd Pandemic

Page 22: CHOLERA - Florida State Universityreeves/ISC2937/Lectures/Cholera.pdf · Cholera Vaccine Oral. des Voyageurs et Cholera Or" and Cholera: Building a Better / Vaccine

Pandemics

History

Sixth Pandemic - 1899-1923

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