Closing the cancer divide for women: An opportunity of lifetimes

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    Closing the cancer divide

    for women:

    An opportunity of lifetimes

    Womens Cancer InitiativePan American Health Organization (PAHO)

    February 5th, 2013

    Felicia Marie Knaul, PhDHarvard Global Equity Initiative, Global Task Force on Expanded Access to

    Cancer Care and Control in LMICs

    Union for International Cancer Control

    Tmatelo a Pecho A:C. MxicoMexican Health Foundation

    WORLD

    CANCER

    DAY

    Seminar

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    January, 2008

    June, 2007

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    Breast cancer champions

    Abish Romeo,

    Mxico, patient Seguro Popular

    Drew G. Faust

    President of Harvard University22+ year BC survivor

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    From anecdote

    to evidence

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    GTF.CCCMembers

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    GTF.CCC:

    Mission and Vision design, participate in implementation, and

    evaluate innovative strategies for expandingaccess to cancer prevention, detection and carethat provide local and cross-country evidence for

    scaling up access to cancer care and control, andstrengthening health systems in LMICs.

    facilitate action through the production of newknowledge and through multi-stakeholder

    frameworks and partnerships that demonstrateeffective models of care that can be replicated andscaled up in LMICs.

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    Global Task Force on Expanded

    Access to Cancer Care and

    Control in Developing Countries

    = global health + cancer care

    WHO, 2012

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    Applies a diagonal

    approach to managechronicity and avoid

    the false dilemmasbetween disease silos

    -CD/NCD- that

    continue to plague

    global health

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    Closing the Cancer Divide:An Equity Imperative

    I: Shouldbe done

    II: Couldbe doneIII: Can be done

    M1. Unnecessary

    M2. Unaffordable

    M3. Impossible

    M4: Inappropriate

    Expanding access to cancer care and control in LMICs:

    1: Innovative Delivery

    2: Access: Affordable Meds, Vaccines & Techs3: Innovative Financing: Domestic and Global

    4: Evidence for Decision-Making

    5: Stewardship and Leadership

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    Cancer is a disease of both rich and poor but

    the poor suffer even more:

    1. Exposure to risk factors

    2. Preventable cancers (infection)

    3. Treatable cancer death and disability4. Stigma and discrimination

    5. Avoidable pain and suffering

    Closing the Cancer Divide

    is an Equity Imperative

    Face

    ts

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    Adults

    Leukaemia

    All cancers

    Source: Knaul, Arreola, Mendez. estimates based on IARC, Globocan, 2010.

    Children

    LOW

    INCOME

    HIGH

    INCOME

    Sur

    vival

    inequa

    lity

    gap

    LOW

    INCOME

    HIGH

    INCOME

    100%

    Facet 3: The Opportunity to Survive

    Should Not, but Is Defined by Income

    In Canada, almost 90% of children with

    leukemia survive.

    In the poorest countries only 10%.

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    Facet 5: The most insidious injustice

    is lack of access to pain controlNon-methadone, Morphine Equivalent opioidconsumption per death from HIV or cancer in pain:

    Poorest 10%: 54 mg per death

    Richest 10%: 97,400 mg per death

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    Mirrors the epidemiological transition

    LMICs increasingly face both infection-

    associated cancers, and all other cancers.

    The Cancer Transition

    Cancers increasingly only of the poor, are

    not the only cancers affecting the poor

    Double burden for health systems.

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    LMICs account for

    >90% of cervicalcancer deaths and

    >60% of breast

    cancer deaths. Bothare leading killers

    especially of young

    women.

    Did you know?????

    The second or third most common

    cause of death, especially among

    young women?

    In LAC, BC is:The cancer transition:

    women

    0

    4

    8

    12

    16

    20101955

    Mexico: cervical cancer.

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    Women and mothers in LMICs

    face many risks through the life cycle

    Women 15-59, annual deaths

    Diabetes

    120,889

    Breast

    cancer

    166,577

    Source: Estimates based on data from WHO: Global Health Observatory, 2008 and Murray et al Lancet 2011.

    Cervical

    cancer

    142,744

    Mortality

    in

    childbirth

    342,900

    - 35%in 30

    years

    = 430, 210 deaths

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    Investing In CCC:

    We Cannot Afford Not ToTotal economic cost of cancer, 2010: 2-4% of global GDP

    Tobacco is a huge economic risk: 3.6% lower GDP

    Inaction reduces efficacy of health and social investments

    Prevention and treatment offers potential

    world savings of $ US 130-940 billion

    1/3-1/2 of cancer deaths are avoidable:

    2.4-3.7 million deaths,

    of which 80% are in LIMCs and women

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    The Diagonal Approach to

    Health System StrengtheningRather than focusing on either disease-specific

    vertical or horizontal-systemic programs, harness

    synergies that provide opportunities to tackle disease-

    specific priorities while addressing systemic gaps andoptimize available resources

    Diagonal strategies: X = > parts

    Bridge disease divides: respond to patient needs, lifecycle

    Generate positive externalities: e.g. womens cancer

    programs also combat gender discrimination

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    The costs to close the cancer divide

    may be less than many fear:

    All but 3 of 29 LMIC priority cancer agents are off-patentPain medication is cheap

    Prices drop: HepB and HPV vaccines

    Delivery & financing platforms & innovations areunderutilized, undeveloped, purchasing is fragmented,

    procurement is unstable

    Pink Ribbon Red Ribbon- a diagonal initiative

    Global Paediatric Financing Entity

    PAHO Strategic Fund: includes NCDs, 2012

    Pink Ribbon Red Ribbon: diagonal partnership

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    Diagonalizing Domestic

    Financing:Integrate cancer care and control into

    national insurance and social security

    programs to express previously suppresseddemand beginning with cancers of women

    and children:

    Mexico, Colombia, Dom Rep, PeruChina, India, Thailand

    Rwanda, Ghana, South Africa

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    Universal Health Coverage in Mexico

    through Seguro Popular

    Horizontal Coverage:

    > 54.6 million Beneficiaries

    VerticalCoverage

    Diseasesa

    nd

    Interventions:

    Expanded

    BenefitPackage

    S P l

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    Seguro Popular: cancer

    Accelerated, universal, vertical coverage by disease

    with an effective package of interventions2005: Cervical cancer

    2006: ALL in children

    2007: All pediatric cancers; Breast cancer2011: Testicular and Prostate cancer and NHL

    2012: Colorectal cancer

    Evidence of impact:Breast cancer adherence to treatment:INCAN:

    2005: 200/600

    2010: 10/900

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    % diagnosed in Stage 4 by state

    # 2 killer of women 30-54

    Only 5-10% of cases in Mexico are

    detected in Stage 1 or in situ

    Poor municipalites: 50% Stage 4; 5x rich

    Delivery failure: Breast Cancer

    Juanita

    Poor/Marginalized

    ec ve nanc a coverage requ res

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    ec ve nanc a coverage requ resattention to the chronicity of illness

    Breast cancer and Seguro Popular

    Primary prevention

    Secondary prevention (early detection)

    Diagnosis

    Treatment

    Survivorship care

    Palliative care

    Large and exemplary investment in treatment

    for women and the health system, yet low

    survival. By applying a diagonal approach,

    this can and is bein remedied.

    S l ti

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    Harness platforms by integrating breast and

    cervical cancer prevention, screening and

    survivorship care into MCH, SRH, HIV/AIDS,

    social welfare and anti-poverty programs.

    Solution:

    Diagonalizing Delivery

    Examples:

    Integration of breast

    and cervical cancerawareness and screening

    into the national anti-

    poverty program

    Oportunidades Results: 000s promoters, nurses, doctors

    Harnessing the primary level of care

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    Where are the opportunities?

    LMICsnot months but whole lifetimes to be gained Focus on prevention but do not stop there!

    No prevent/treat dichotomization

    Do not take prices as fixed or givenprice permeability

    Harness global and national health system and financingplatforms

    Redefine and reformulate health systems to manage chronicity

    Innovate in implementation, delivery and financing Evaluate, replicate and scale up

    Leapfrog and give forward

    Harness cancer to strengthen health and social systems

    Recognize LMICs as part of a global solution:

    investment in learning, research and human beings

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    Be anoptimist

    optimalist

    Expanding access to cancer care and control in

    LMICs: Should, Could, and Can be done

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    From anecdote

    t id