COST - MODERNET | Monitoring Occupational … Report... · Web viewOur argument, presented at the EU conference in Brussels in December 2013 and reinforced in our publications, is

COSTDomain Committee

"Domain Individuals, Societies, Cultures and Health"

COST Action IS1002Start Date 09-11-2010

MODERNET: A network for development of new techniques for discovering trends in occupational and work-related diseases and tracing new and emerging risks

MONITORING PROGRESS REPORT

Reporting Period: from 9-11-2010 to 08-11-2014

This Report is presented to the relevant Domain Committee.It contains three parts:

I. Management Report prepared by the COST Office/Grant HolderII. Scientific Report prepared by the Chair of the Management Committee of the ActionIII. Previous versions of the Scientific Report; i.e., part II of past reporting periodsIV. Evaluation Report prepared by the “ad hoc” Evaluation Panel, established by the Domain Committee, and edited by the COST Office. V. DC General Assessment prepared by the Domain Committee

Appendices: Annex 1 –Impact of networking Annex 2 –Dissemination Annex 3 –Workshops and Final conference abstracts Annex 4 –WGs reports

Confidentiality: the documents will be made available to the public via the COST Action web page except for chapter II.D. Self-evaluation and IV. DC General Assessment.

Executive summary (max.250 words): MODERNET is a network for the development of new techniques for studying trends in occupational and work-related diseases and for discovering new or emerging risks. The two main drivers for the concept were: [a] The realisation that the EU did not have reliable enough means of measuring trends in occupational disease (OD). [b] The need for the collective and early identification of new OD and health risks. The four Working Groups in this Action therefore addressed: 1. Quality of data collection; 2. Improving methods for the analysis of trends; 3.Developing techniques for tracing newly occurring OD, and 4. Dissemination of new knowledge on OD. The Action surveyed existent data sources for monitoring the frequency of OD in the EU and developed recommendations for OD registration. It undertook a Cochrane Review on “Interventions to increase the reporting of OD by physicians”. It analysed multinational trends in a range of OD. It developed and applied methodology for analysing national changes in incidence of OD as well as demonstrating the impact of national and EU level interventions to prevent OD. The Action developed and used a tool based on a sentinel clinical system to detect new work related diseases (OccWatch project). An interactive website was established (http://www.costmodernet.org) as well as using scientific journals and social media for dissemination. The network eventually comprised 17 countries and 2 institutions from non-COST countries, and has trained 14 researchers through Short Term Scientific Missions and supported about 65 more in its scientific workshops and conferences.

I. Management Report prepared by the COST Office/Grant Holder

I.A. COST Action Fact Sheet

COST Action IS1002 Modernet, a network for development of new techniques for discovering trends in occupational and work-related diseases and tracing new and emerging risks

Domain Individuals, Societies, Cultures and Health (ICSH)

Action details:

CSO Approval: 25/05/2010 End date: 08/11/2014Entry into force: 20/08/2010 Extension:(day/month/year)

ObjectivesOccupational diseases (ODs) impose a heavy burden on both workers and employers and represent enormous economic costs. In general, the information on incidence and prevalence of occupational diseases is rather poor and inconsistent between countries, and there is an urgent need for new methods and instruments to trace new and emerging occupational health (OH) risks. This Action’s objectives are to develop a network for exchange of knowledge on, and setting the basis for comparative evaluation and development of new techniques to enhance the information on trends in ODs, on discovering and validating new OH risks more quickly (data mining, workers’ and physicians’ reporting coupled with novel statistical techniques) and use of modern techniques to discuss and disseminate information (platforms, social media).

Parties: list of countries and date of acceptance

Belgium 30-09-2010 Germany 14-09-2010 Portugal 13-10-2010Bosnia and Herzegovina 05/12/2012 Iceland 11-01-2011 Romania 20-08-2010Croatia 04-05-2011 Ireland 07-02-2011 Spain 04-11-2010Czech Rep. 23-09-2010 Italy 10-09-2010 Switzerland, 24-9-2013Finland 20-08-2010 Malta 29-7-2013 United Kingdom 20-08-2010France 20-08-2010 Netherlands 20-08-2010FYR of Macedonia 22-11-2011 Norway 16-09-2010

Intentions to accept: Membership of Turkey was in principle accepted by mail by the MC members in March 2013. Membership required approval by the National Coordinator of Turkey. Approval was denied, so Turkey does not participate in the Action.

Other participants: Participating Institutions from Non-COST countries: Australia, Monash University; and Albania, Institute of Public Health

Chair: Professor Raymond Agius The University of Manchester, Centre for Occupational & Environmental Health, M13 9PL Manchester United Kingdom [email protected]

DC Rapporteur: Prof. Rita ZUKAUSKIENE DC Rapporteur of IS1002 ISCH Mykolas Romeris University Ateities 20 LT08303 Vilnius Lithuania [email protected]

Science Officer: Dr Luule MIZERA , [email protected]

Administrative Officer: Leo Guilfoyle, [email protected]

Action Web site: Grant Holder Representativehttp://www.costmodernet.org Eugenie Quartier, [email protected]

Gwendoleyn Pinas, [email protected] Lenderink, [email protected]

mailto:[email protected]



http://www.costmodernet.org/



http://www.cost.eu/about_cost/who/(type)/5/(wid)/36569



Working Groups (names and affiliations)

WG 1 Quality of data

Stefano Mattioli (University of Bologna, Italy; WG leader), Dick Spreeuwers (Sanecon, Netherlands), Yogi Samant (Labour Inspectorate, Norway), Melanie Carder (University of Manchester, UK), Antoon de Schrijver (University of Antwerp, IDEWE, Belgium), Viorel Lefter (The Academy of Economic Studies in Bucharest, Romania), Riita Sauni (Finnish Institute of Occupational Health, Finland), Kieran Sludds (Health and Safety Authority, Ireland), Giuseppe Campo (INAIL, Italy), Peter Noone (HSE, Ireland), Stefan Scholz (Suva, Switzerland), Elisaveta Stikova (Institute of Public Health, FYROM), Daniela Pelclova (Charles University in Prague, Czech Republic), Tore Tynes (National Institute of Occupational Health, Norway), Malcolm Sim (Monash University, Melbourne Australia), Pavel Urban (National Institute of Public Health, Czech Republic), Madeleine Valenty (INVS, France), Axel Wannag (Labour Inspectorate, Norway), Stefania Curti (University of Bologna, Italy), Stéphanie Rivière (InVS, France), MaylisTelle-Lamberton (ANSES, France ), Kirsi Karvala (Finish Institute of Occupational Health, Finland), Julian Mamo (University of Malta, Medical School, Malta), David Miedinger (SUVA, Switzerland), Nurka Pranjic (University of Tuzla, Bosnia), Naum Veslievski (Worker's Health Center Ramazzini-Strumica, FYROM), Neville Callega (University of Malta, Medical School Malta), Mounia El-Yamani (InVS, France)

WG 2 Trends Analysis Roseanne McNamee (University of Manchester, UK) (WG leader), Jill Stocks (University of Manchester, UK), Teake Pal (NCvB/Coronel Institute, AMC, University of Amsterdam, Netherlands), Christophe Paris (CHU Nancy, Nancy, France), Stefan Gravemeyer (Deutsche Gesetzliche Unfallversicherung (DGUV), Germany), Henk van der Molen (NCvB/Coronel Institute, AMC, University of Amsterdam, Netherlands), Lynda Bensefa-Colas (Hôpital Cochin, France), Serge Faye (ANSES, France), Melina Lebarbier (ANSES, France), Martijn Schouteden (IDEWE, Belgium), Joseph Ngatchou-Wandii (University of Lorraine, France), Yurika Iwatsubo (InVS, France), Sabira Smaili (InVS, France)

WG 3 Newly occurring occupational diseases

Vincent Bonneterre (CHU Grenoble (Grenoble Teaching Hospital), France, WG leader), Dominique Bicout (CHU Grenoble (Grenoble Teaching Hospital), France), Pierluigi Cocco (University of Cagliari, Italy), Jorge Costa-David (European Union), Regis de Gaudemaris (CHU Grenoble (Grenoble Teaching Hospital), France), Lode Godderis (KULeuven, IDEWE, Belgium), Begoña Martinez (University of Zaragoza, Spain), Stephan Keirsbilck (KULeuven, IDEWE, Belgium), Nicole Palmen (RIVM, Netherlands), Consol Serra (Univeritat Pompeu Fabra, Barcelona, Spain), Erik Tielemans (TNO, Netherlands), Hilde Cnossen (TNO, Netherlands), Catherine Buisson (INVS, France), Dirk Pallapies (Institute for Prevention and Occupational Medicine - German Social Accident Insurance, Germany), Natasa Janev (University of Zagreb, Croatia), Gert van der Laan (NCvB/Coronel Institute, AMC, University of Amsterdam, Netherlands), Raymond Agius (University of Manchester, UK), Martin Seed (University of Manchester, UK)Andrea Lastovkova (Charles University in Prague, Czech Republic), Godewina Mylle (IDEWE, Belgium), Tonje Strömholm (Labour Inspectorate, Norway), Gerald Wanka (DGUV, Germany), Adriano Papale (INAIL, Italy), Arben Luzati (Institute of Public Health, Albania), Delphine Rieutort (CHU Grenoble (Grenoble Teaching Hospital), France)

WG 4 Dissemination

Claudio Colosio (University of Milan, Italy, WG leader), Annet Lenderink (NCvB/Coronel Institute, AMC, University of Amsterdam, Netherlands), Hans Magne Gravseth (National Institute of Occupational Health, Norway), Annemarie Money (University of Manchester, UK), Gerard Lasfargues (ANSES, France), Ari Kaukiainen (LocalTapiola General Mutual Insurance Company, Finland), Jadranka Mustajbegovic (University of Zagreb, Croatia), Stefan Mandic-Rajcevic (University of Milan, Italy), Ecaterina Gica (The Academy of Economic Studies in Bucharest, Romania), Louise Hussey (University of Manchester, UK), Elena Bottoli (University of Bologna, Italy)

I.B. Management Committee member list

Name Country E-mail

Prof. Arben Luzati Albania (non-COST) [email protected] Prof. Malcolm Sim Australia (non-COST) [email protected] Prof.Antoon de Schryver Belgium [email protected] Lode Godderis Belgium [email protected]. Sofie Vandenbroeck Belgium (sub) [email protected]. Nurka Pranjic Bosnia and Herzegovina [email protected] Prof.Jadranka Mustajbegovic Croatia [email protected] Janev Croatia (sub) [email protected] Urban Czech Republic [email protected] Bittner Czech Republic [email protected] Sauni Finland [email protected] Kaukianinen Finland [email protected] Dr.Kirsi Karvala Finland (sub) [email protected] Stikova Former Yugoslav Republic

of [email protected]

Dr. Naum VESLIEVSKI Former Yugoslav Republic of Macedonia (sub)

[email protected]

Dr Vincent Bonneterre France [email protected] Maylis Telle-Lamberton France [email protected] Prof Regis de Gaudemaris France (sub) [email protected] Dr Dirk Pallapies Germany [email protected] Gravemeyer Germany [email protected] Wanka Germany (sub) [email protected] Bruening Germany (sub) [email protected] Asta Snorradottir Iceland [email protected] Sludds Ireland [email protected]. Peter Noone Ireland [email protected] Dr.Claudio Colosio Italy [email protected] Mattioli Italy [email protected]. Neville Callega Malta [email protected]. Julian Mamo Malta [email protected] Gert van der Laan Netherlands [email protected] Annet Lenderink Netherlands [email protected] van der Molen Netherlands (sub) [email protected] Samant Norway [email protected] Magne Gravseth Norway [email protected] Wannag Norway (sub) [email protected]. Tonje Stromholm Norway (sub) [email protected]* Portugal * left after one meetingProf.Viorel Lefter Romania [email protected] Viorica Petreanu Romania [email protected] Ecaterina Gica Romania (sub) [email protected]. Begoña Martinez Jarreta Spain [email protected]. Consol Serra Pujadas Spain [email protected] Rafael Pinilla Pallejà Spain (sub) [email protected] David MIEDINGER Switzerland [email protected] Dr Stefan SCHOLZ Switzerland [email protected]. Roseanne McNamee United Kingdom [email protected]. Raymond AGIUS United Kingdom [email protected]. Jill Stocks United Kingdom [email protected]














































I.C. Overview activities and expenditure 1 April 2014 to 14 October 2014

Total Action Budget: € 407.135,00

Year 1 (€) Year 2 (€) Year 3 (€) Year (4) Total (€)

Grant Budget 70.000,0

0

96.570,00 111.565,0

0

129.000,0

0

407.135,00

Science Expenditure 40.523,6

6

72.546,36 83.620,61 110.519,9

0

307.210,53

Meetings 35.630,99 66.463,36 75.450,61 101.816,90 279.361,86

STSMs 0,00 4.500,00 6.660,00 7.100,00 18.260,00

Training school 0,00 0,00 0,00 0,00 0,00

Dissemination 4.892,67 1.583,00 1.502,00 1603,00 9.580,67

OERSA 0,00 0,00 0,00 0,00 0,00

Management 6.078,22 9.797,34 12.259,49 16.578,00 44.713,05

Total eligible 46.601,8

8

82.343,70 95.880,10 127.097,9

0

351.923,58

Meetings

Type of meeting Place Dates P (TR) COST (€) Total (€)

MC + WGs Amsterdam 6 April 2011 44 (27) 14.320,51

MC + WGs Manchester 17-18 Nov. 2011 51 (24) 21.310,48

WG1 (Cochrane) Paris 13-15 Feb. 2012 7 (6) 3.224,83

MC + WGs Leuven 12-14 June 2012 61(41) 31.668,05

MC + WGs Rome 7-9 Nov. 2012 57(40) 31.570,48

WG1 (Cochrane) Tampere 5-7 Feb. 2013 8(5) 3.590,57

MC + WGs Bucharest 29-31 May 2013 64(48) 41.434,59

MC + WGs Paris 16-18 Oct. 2013 76(39) 30.425,45

MC + WGs Zaragoza 8-11 April 2013 68(50) 46.107,08

WGs (Signal detection) Paris 17-7-2014 13(4) 943,80

Final Action meeting Bologna 13-14 Oct. 2014 77(73) 54.765,90

STSM

Beneficiary Date Place Cost (€) Total (€)

Dr. Andrea Zavadilova 14-21 June 2012 Manchester 1000,00

Mrs. Annet Lenderink 1-5 Oct. 2012 Trondheim/Oslo 1000,00

Dr. Vincent Bonneterre 1 Oct. – 30 Nov. 2012 Manchester 2500,00

Dr. Nataša Janev-Holcer 4-8 March 2013 Helsinki 1200,00

Dr. Stefania Curti 1-14 Sep. 2013 Manchester 1600,00

Dr. Stefan Mandic-Rajcevic 19-26 Oct. 2013 Grenoble 1100,00

Dr. Lynda Bensefa-Colas 21-30 Oct. 2013 Manchester 1400,00

Dr. Gaia Varischi 4-10 Nov. 2013 Amsterdam 1360,00

Dr. Jill Stocks 19-26 May 2014 Paris 1000,00

Dr. Madeleine Valenty 2-6 June 2014 Manchester 800,00

Dr. Yuriko Iwatsubo 2-6 June 2014 Manchester 800,00

Ms. Sabira Smaili 2-20 June 2014 Manchester 2400,00

Begoña Martinez-Jarreta 19-26 Aug. 2014 Manchester 1000,00

Martijn Schouteden 29 Sep.- 3 Oct. 2014 Grenoble 1100,00

Dissemination

Title Date Organization COST (€) Total (€)

Web development and maintenance 2011 NCOD/AMC 4.892,67

Website maintenance 2012 NCOD/AMC 1.502,00

Posters (2, printing) 2012 Univ. of Manchester 81,00

Website maintenance 2013 NCOD/AMC 1510,00

Website maintenance 2014 NCOD/AMC 1548,00

Modernet Poster printing 2014 Univ. of Manchester 55,00

Administration and coordination (FSAC)Date COST (€) Total (€)

From To

Administrative and financial support AMC 1-12-2010 30-11-2011 6.078,22




II. Scientific Report II.A Innovative networking

COST Modernet’s position in the EU environment

The first achievement in the 'process' of the network was in setting up, for the first time in the EU, a collaborative network of researchers in the areas of measuring temporal trends in occupational diseases (ODs) and in detecting new and emerging occupational health risks.

In terms of a collective conclusion by the network of the needs within the EU, it was deemed essential for all stakeholders including policy makers, occupational health professionals as well as employees, employers and the public to have reliable information on the trends in incidence of work related disease so as to be better able to intervene and achieve reductions in risk through legislation, enforcement and education. The network also concluded that interventions ought also to be evaluated using corresponding reliable measurements of incidence. The challenges that hinder such reliable measurements had prompted EUROSTAT to effectively stop prioritising and to curtail publication of data on occupational disease (OD) frequency in the member states. Nevertheless, as outlined hereunder the innovative networking of this COST Action permitted it to successfully achieve these important needs. Therefore, while the current EUROSTAT position is that the diversity of data systems makes it hard to compare incidence across countries, our group has reached the conclusion that comparisons of temporal trends is possible from these systems. Furthermore, these comparisons offer the opportunity to evaluate the impact of policy interventions – at EU or national level - on workers’ health. The network recognised the equally important necessity to identify rarer or newer OD and work related health risks. It is heartening to note that the European Agency for Safety and Health at Work has also perceived the same need (as exemplified by its recent publication of a "Scoping study for a foresight on new and emerging occupational safety and health (OSH) risks and challenges"). Moreover the work of the Action is complementary to that of the European Agency as the network addressed the need (as yet unmet in the EU) to have collective international sentinel reporting schemes to trace novel diseases or discover new circumstances of exposure leading to disease. Looking to the future the innovative networking of the Action realises that the biggest challenge relates to ‘ideal prevention’ which would require the capacity to predict, and thence pre-empt, hazards to health even before they become manifest as disease in workers.

In this report a more detailed description of the achievements of the innovative networking is given in the sections below dealing with each of the four Working Groups respectively. However the paragraphs below summarise shared principles and outlooks.

COST Modernet’s innovative activities

Firstly Modernet, resourced by the EU COST Action funding, established a baseline of the knowledge of the type and quality of relevant extant information amongst the participating states. Then it developed, disseminated and eventually applied scientific methods in several domains for measuring trends, evaluating interventions, and detecting risks amongst the member states. Part of the innovation consisted of the search, testing, and assessment of the relevance for Modernet objectives of the methods used in other scientific fields. These include methods for policy evaluation as used in social sciences and methods for detecting new risks.

From innovation to practiceThese methods have been put into practice: for example 10 countries collaborated, for the first time, in sharing data from their national systems to evaluate and compare trends in work-related disease in the EU from 2000 to 2012. Our published methods evaluating interventions to prevent WRDs were initially developed in one country but as a result of the network they are being applied collaboratively - with corroborated findings in other EU states

From practice in innovative networking to disseminationSubjectively it was a pleasure to see members greet each other at meetings, to experience a common 'buzz' at what was being achieved and to carry on this interaction through social media and other electronic means in between the face to face meetings. The more difficult task was to extend this to the wider community. As described in more detail in the report of WG4, the network has not only used the conventional peer-reviewed but relatively passive means of dissemination but it has gone on to adopt a wide range of modern media to achieve dissemination and two way interaction with its stakeholders.

Modernet’s legacy and future funding opportunitiesModernet started as a network about 4 years before the award of funding for the COST Action. It is carrying on beyond the conclusion of COST support. Various research collaborations (some funded by national sources) are continuing as are the means of dissemination. Some aspects of the activity of the network have formed the basis of an application to Horizon 2020 (“ANTICIPATE” – Anticipation and Prevention of Occupational and Environmental Health Issues in EU citizens) although the outcome of this application is still awaited.

II.B. Inter-disciplinary networking

Nature of inter-disciplinarityOne of the main accomplishments and assets of COST Modernet has been its inter-disciplinarily. It generated a very collegial and integrated platform for intellectual exchanges between all its members of different disciplines and experience. This built trust as well as mutual understanding and respect for the perspectives and varied potential contributions of all its members many of whom had not known each other before this COST Action. The output of the network has relied on close multidimensional working between occupational physicians, occupational hygienists, safety engineers, toxicologists, epidemiologists and statisticians and other disciplines. The interactions were dynamic and changing for example with migrations and cross-fertilisations of ideas between the various groupings. They enabled common needs to be agreed by collective negotiation, and concepts to be tested challenged and to evolve.

How inter-disciplinarity has been put into practiceA good example of this is how the quality criteria determined by Working Group 1 (WG1) addressed various issues from medical ones of diagnosis and attribution to statistical ones. The work WG1 on quality of data relied on close working between physicians, epidemiologists and statisticians amongst others. Thus the quality criteria determined by this WG addressed various issues from medical ones of diagnosis and attribution to statistical ones, and hence in turn underpinned the work of the other WGs. In this manner WG1 proposed ideas on how to specify the “ideal” register of data regarding ODs, how to promote and perform evaluation of effectiveness of interventions to increase OD reporting (new laws or surveillance systems), and how to prepare search-strings to explore the

literature regarding occupational aetiology of diseases (a useful tool to execute systematic reviews in the field of aetiology of ODs).

Correspondingly Working Group 2 (WG2) dealing with national trends in WRDs and methods for evaluating interventions, was led by statisticians and epidemiologists, but also included physicians and other occupational health specialists closely involved in ‘generating’ the data (i.e. diagnoses, and ancillary demographic and occupational ‘fields’) or managing data systems. In the collection of data, this inter-disciplinarity was also manifest with sources from a wide range of agencies – some closely linked with insurance schemes, others linked to national health care provision, while other schemes were totally voluntary.

In detecting new hazards, besides medical and toxicology expertise, epidemiology, computer science and occupational hygiene within MODERNET, networking with other groups was especially valuable in Working Group 3 (WG3). Thus WG3 welcomed experts with skills in text mining from the TNO institute (NL) who had previously developed an Emerging Risk Identification Support Service in the field of food safety. The experience of EFSA and their Emrisk unit, dedicated to the detection and expertise of new risks related to food, was also a source of inspiration, as well as other vigilance methods (e.g. pharmacovigilance). Other output relied on collaboration with experts in Geographic Information Systems (GIS) or in Quantitative Structure Activity Relationships – important tools in identifying or predicting new OD hazards.

Close links with national institutions in charge of health and safety was also essential, notably with ANSES in France which continues to offer a support for the Modernet OccWatch project offering the opportunity for clinicians to share detailed information about cases thought to be sentinel of new ODs/WRDs.

Another example of collaborative work between the working groups is the work of WG1 and WG3 on the issue of the “convincing evidence” that has to be reached to conclude that a certain disease, in specified occupational exposure conditions, could be considered work-related. Such judgements are based on interdisciplinary discussions between experts ranging from physicians to statisticians.

The whole Action worked very coherently both in achieving the above goals and in their final dissemination through Working Group 4. An incipient special issue of the peer-reviewed journal “Occupational Medicine” will tangibly demonstrate both the outputs mentioned in the previous section, and the inter-disciplinarity addressed in this section. It is anticipated that the authoritative findings, validated methods and generalisable recommendations that will result should therefore besides scientific impacts, also have socio-economic impacts. These impacts are particularly relevant for policy makers wishing to determine the burden of ODs, the value of interventions, and the likely emergent threats.

II.C. New networking

ParticipantsDuring the life of the Action from its first launch in November 2010 about sixty additional new members joined. The total number of individual participants involved in the Action work was about 70 at any one time. Of the current 85, there are 36 females (42%) and 25 (29%) Early Stage Researcher (ESR) participants

ESR and trainingEarly Stage Researchers (ESRs) continue to be intimately involved both in the processes such as networking activities, and in the output including presentations at COST Modernet meetings as well as at other conferences such as the EU meeting on Occupational Diseases in Brussels in 2013. A number of STSM participants (an overview at the end of this report) including ESRs took datasets with them to analyse with the help of staff and methods in the host centre – thus fostering new collaborations which are being translated into scientific publications. Moreover the biannual Action conferences and workshops strongly encouraged and featured presentations by the ESRs guided by their mentors. Therefore in spite of the fact that the budget precluded the organisation of a Training School as such, extensive and very customised and detailed practical training was given to the ESRs.

COST Modernet websiteThe comprehensive project website with user-interactive functions which was set up early in the COST Action has continued to grow: http://www.costmodernet.org/The website informs both participants and the wider public about the aims, structure, composition and outputs of the project. It also continues to provide a secure forum for online information sharing, communication and debate between the MODERNET consortium network members. Among other useful information, summaries of STSM can be found there. It is also worth mentioning that the Consortium is actively present in the most important social networks (LinkedIn, Facebook, Twitter, and Research Gate). Plans have been made to continue these activities as far as possible as a legacy of this COST Action.

Over the last year two Management Committee meetings combined with conferences / workshops have been undertaken (Paris - October 2013, and Zaragoza April 2014) and the third meeting will be the final Action meeting on 13-14 October 2014 in Bologna (Italy), back to back with the yearly Congress of the Italian Society of Occupational Health and Safety (SIMLII) and a meeting of two Scientific Committees of the International Commission on Occupational health (ICOH) on Occupational Health Surveillance (15-16 October 2012).

The meetings already conducted, have resulted in tangible interdisciplinary work towards this Cost Action’s dissemination of its scientific results programme in the peer reviewed literature, and the forthcoming one is being developed in the same line. The activities of passive dissemination conducted by the Consortium will culminate in the publication of a special edition of the peer-reviewed journal ‘Occupational Medicine’: Ten publications have been prompted by the Action so far, with a further 14 anticipated in the special edition, and more than other 20 elsewhere. However besides these network-specific publications, more than a further hundred works relevant to the Action’s objectives of identifying new OD or measuring trends in OD incidence have been published by MODERNET members. The list of publications and other outreach activities that resulted from COST networking through the Action is given in the Annex). This COST Action was either an essential feature (as in the Cochrane project, or the Occwatch sentinel clinical system) or an adjuvant asset in members raising research funds; such as €1.8M from UK and IE governmental agencies for measuring trends in OD in those countries. A mentioned there was also collaboration with various national agencies especially the French Institution (ANSES) supporting the national network for work related disease vigilance and prevention (RNV3P).


Networking with other groupsAt a more strategic level networking links have been forged with another COST Action: ISCH COST Action TD1206 Standerm, whose Chair (Professor Swen John) has been invited to address our final COST Action meeting in Bologna in October 2014, as well as with public health colleagues with whose wider environmental remit there is a common interface. Similarly contacts were made with the US AOEC (Association of Occupational & Environmental Clinics) in order to launch collaborations regarding new Work Related Diseases.

II.D. Self-evaluation

The consensus of opinion of the management committee (MC) is that the main successes of the Action were:

• The establishment of a very collegial international and inter-disciplinary network which included Early Stage Researchers as peers, fostered their enthusiasm and supported their training needs within the common purposes mentioned below:

• The development of recommendations on the best means of motivating physicians and others to recognise and report OD, suitable means of data collection, taking account of national feasibility, and the standards of the quality of data essential to measure and track trends in the burden of occupational disease in the EU

• The sharing and application of methodology to estimate the true temporal trends in the reported incidence of occupational diseases (OD) in Europe, as well as the development and application of methods to evaluate national or EU level interventions aimed at reducing the risks of OD

• The development and international application of methods to identify new ‘signals’ of emerging work related diseases and to help predict new hazards. Most notable is the launch of a European sentinel clinical watch system (OccWatch project), designed to capture case-reports of potentially new work related diseases, to look for similar cases in other countries, to ensure a common expertise was applied to the cases, and finally to disseminate information to stakeholders when relevant for preventive purposes.

• The utilisation of a variety of methods (from peer review literature to the Web, and social media) for the continuing dissemination of the above.

Arguably a drawback of the COST Action has remained the effort and time involved in the work, especially with Universities often place emphasis on primary hypothesis driven fully externally funded research. Nevertheless we still believe that this COST Action has been an invaluable collaborative opportunity acting as a stepping stone to further international and interdisciplinary collaborations with scientific as well as socio-economic impact.

One hopeful expectation had been that the Horizon 2020 document in the year preceding the December 2013 identified the following EU needs of “… improving surveillance and preparedness…. &… improving scientific tools and methods to support policy making and regulatory needs ….” which mapped out remarkably well with the agenda, activity and output of the MODERNET COST Action. However since these terms were no longer featured in the official H2020 call of December 2013, the scope of the application of a number of the Modernet partners to H2020 does not cover the whole of the Modernet agenda.

WG1: quality in data collection

Leader: 2011, Dick Spreeuwers; 2012-2014, Stefano Mattioli

Since the first meeting of the COST Action-Modernet, Working Group 1 (WG1) was

established with the aim of promoting the quality of the data collected regarding

occupational diseases in the different EU Countries,.

In 2012 our aims were reformulated as follows:

1. To evaluate the effect of interventions aimed at increasing the reporting of

occupational diseases through a Cochrane review (substituting the originally

proposed Delphi study)

2. To study the differences in the classification systems of occupational diseases

used in different European countries

3. To increase quality in the collection of literature data on occupational diseases,

promoting the use of efficient search strings

4. To define the level of evidence needed to scientifically define a disease as a

new work-related disease

5. To study the nomenclature utilised in the different databases of occupational

diseases

Regarding the goals that the WG1 had to achieve, on the quality of work-related diseases

data, we obtained valuable results, during the fruitful meetings held during these years.

Result 1

A Cochrane review on interventions to increase the reporting of occupational diseases,

whose Protocol won an award as the best 2012 proposal, is in its final step, after the last

review. Seven members of our WG1, coming from 5 different countries, contributed to the

Cochrane review, demonstrating the usefulness of the meetings (and of two extra-

meetings) that permitted us to work together effectively and efficiently.

The review showed that we need interventions to increase the number of notified

occupational diseases and that the effectiveness of some interventions (e.g. new

surveillance systems) has yet to be studied.

Result 2 (aim 2 + aim 5)

Some other members of our WG1, cooperating with colleagues of WG2, explored the way

in which the European Countries classify work-related diseases, also identifying the

different nomenclatures adopted. This survey demonstrated differences and shortcomings

of the various European systems, providing conclusions regarding the “ideal” data-base in

the field of occupational diseases. The results of this experience were used to prepare a

paper, since submitted for publication.

Result 3

A way of preparing search-strings to explore the literature has been obtained from the

experience of the last published paper on the strategies for detecting articles on

agricultural workers’ diseases. Researches on occupational origin of disease could be

facilitated by the use of such kind of tools.

Result 4a

The concept of “occupational diseases” versus “work-related health problems” has been

debated in a report produced by a WG1 sub-group, posing the basis for a paper to be

published on a scientific journal.

Result 4b

In collaboration with colleagues of WG3, a WG1 sub-group worked on a review of the

articles reporting proposals on the issue of the “convincing evidence” that has to be

reached to say that a specific disease, in certain occupational exposure conditions, could

be considered work-related. After having planned the search strategies, we retrieved

information from the literature and presented the results during the final meeting in

Bologna. This issue will be useful also in the next future, considering the increased

relevance of correctly executed aetiological reviews concerning diseases of putative

occupational origin.

STSMs

One member of WG1 executed an STSM, to exchange and learn about methods to permit

an increase in the number of occupational diseases notified by general practitioners.

Broader achievements

The MODERNET WG1 collaboration has led to:

Increased understanding of the relevance of interventions aimed to increase the reporting

of occupational diseases;

Increased understanding of strengths and differences in surveillance systems in Europe;

Dissemination of efficient search strings to retrieve papers on occupational diseases;

Increased understanding of the importance to execute - correctly – systematic reviews on

occupational aetiology of diseases.

We believe that our work on data quality directly contributes to the key strategic objective

of the EU Strategic Framework on Health and Safety at Work 2014-2020 to improve

statistical data collection and analysis. Moreover, it contributes to facilitate the evidence-

based evaluation of occupational origin of diseases

WG2: application of new techniques and methods for analysis of trends in occupational diseases

Leaders: R McNamee, J Stocks

In 2010, WG2 consisted of members from only three countries which collected data on

incident cases of work-related diseases, including occupational diseases, diagnosed by

physicians. It became clear that there was a great diversity of methodologies for collection

of data within these purpose-built surveillance schemes. By the end of the Action, there

were participants from 10 European countries revealing further diversification of methods.

The 2013 EU report on the current situation in relation to occupational diseases’ systems

in EU Member States noted that “The diversity …makes it hard to compare the statistics

between countries”. An initial but ongoing task for WG2 was therefore to clarify whether

any valid international comparisons could be made. Our argument, presented at the EU

conference in Brussels in December 2013 and reinforced in our publications, is that while

the diversity of approaches to surveillance might invalidate comparisons of absolute

incidence, this would not necessarily be a problem for comparisons of within-country

change in incidence, i.e. ‘time trends’.

Our first methodological goal thereafter was to describe how best to estimate temporal

trends in true incidence of Work-Related Disease in each country from surveillance data.

The critical issue is temporal biases – either structural changes in the surveillance scheme

or external factors such as changes in awareness -which could lead to artefactual changes

in the number of cases captured by surveillance schemes. To be valid, any statistical

analysis of ‘trends’ would need to account for these biases. Our discussions revealed that

the nature of these biases also varied between countries. Nevertheless we agreed on a

flexible form of statistical analysis, carried out separately for each country and taking

account of local factors. Our second goal, related to the first, was to implement this

methodology to compare temporal trends in as many EU countries as is feasible.

Results 1: Both agreed methods and application are described in our paper (Stocks,

McNamee al. Trends in incidence of occupational diseases in 10 European Countries

2000-2012, accepted for publication by Occupational and Environmental Medicine, Dec

2014). We believe that this is the first such comparison of time trends in work-related

diseases between European countries

As explained by WHO, surveillance schemes should also allow evaluation of the impact of

public health interventions, including the impact on incidence of work-related diseases of

legislative interventions to control exposures at national or EU level, to control exposures.

The third and fourth objectives of WG2, outlined in our application were to show how one

might evaluate the impact of such interventions using data from occupational surveillance

schemes using three ‘case studies’.

For a comparison of incidence ‘before and after’ an intervention to be valid, surveillance

scheme data should be free from temporal bias. As this cannot be guaranteed, we

proposed a better design comparing ‘before and after’ change for the targeted disease(s)

and for a control disease from the same surveillance scheme. We implemented this design

in several studies.

Results 2: During the course of the COST action, this design was implemented to

evaluate 10 interventions in the UK (see Stocks et al, Turner et al). A collaboration

between France and UK developed during the Action has resulted in a publication led by

Bensefa-Colas, submitted in December 2014 to Occupational and Environmental

Medicine: "Effectiveness of preventative actions on occupational dermatitis to chromate in

cement in France: comparison with UK.".

STSMs: Four visits were made to exchange and learn about methods for trends estimation

and intervention evaluation in different countries



Increased understanding of strengths and differences in surveillance systems in Europe

Increased understanding of potential biases (for trends) and how they might be dealt with

Dissemination of ‘best’ practice in analysing trends and interventions

Renewed enthusiasm for collection of European statistics

We believe that our work on trends directly contributes to the key strategic objective of the

EU Strategic Framework on Health and Safety at Work 2014-2020 to improve statistical

data collection and analysis. Our work on evaluation of legislative interventions can also

inform national and EU policy both now, and in the future by showing how best to do this.

WG3: “New techniques for tracing newly occurring work-related diseases”

Leader: Vincent Bonneterre

Context

It is a societal challenge to detect early New Work-Related Diseases (WRD) in order to

take appropriate actions in due time. If efforts have already been made to identify

potential “drivers” of new occupational risks (Emerging Risk Observatory relying on

expert focus set up EU-OSHA), occupational health surveillance, relying on medical

data, is currently not adapted to this purpose, as most of the surveillance systems are

dedicated to monitor already well characterized occupational diseases. Regarding the

detection of new issues, the occupational health field is showing an important delay

contrarily to other medical fields already covered by vigilance systems (toxicovigilance,

pharmacovigilance, nutrivigilance in some countries, …). Convinced that a strong and

structured cooperation between EU centres specialized in WRD clinical and research

activities could strongly intensify their ability to detect early newly occurring WRD,

investigate, disseminate and monitor them, we dedicated one Modernet WG to this

topic with the following specific identified aims.

Aims

1. Exchange of information on possible newly occurring occupational diseases

(sharing of clinical cases)

2. Development of a defined procedure for signal tracing and follow up

3. Explore quantitative methods for signal tracing and refine them

4. Progress on alert systems

Result 1 (aims 1)

First of all, we proposed a common definition of what has to be considered as new

work-related diseases. Briefly, we defined them as either “new couples” between a

disease and an occupational agent, or as “new triads” “disease x agent x circumstance

of exposure” (which means a disease already reported to an agent, but occurring in a

new occupational context). We built a common template in order to share our cases

within a structured way, and many case-reports / new issues were shared and discuss

at the different meetings (cf minutes).

Result 2 (aims 2 & 4)

Initiatives have been developed at national level by Modernet partners for capturing

potentially new WRD (ex: French RNV3P approach for detection and investigation of

new WRD, NL and Be SIGNAAL tool). An alert system (graded actions according to an

algorithm) has been created at French level, and is now operational from 2014 (cf

RNV3P scientific report 2014, available on ANSES website).

We also developed a common web-tool to share the case-reports related to new issues

at trans-national EU level (currently within Modernet partners). This sentinel clinical

watch system is named « OccWatch » (for Occupational Watch), available (secured) at

https://occwatch.anses.fr/. Its aim is to 1) Capture case-reports of potentially new

WRD, 2) Gather comments of experts on each case [challenge diagnosis, exposure,

work-relatedness, hypotheses on causative agents, physiopathology and prevention

issues], seek similar cases in the different databases (French RNV3P, UK THOR, NL

NCOV, Italian Malprof, Belgian Precube, etc. ) in order to analyse the relevance of

clinical signals, 3) Produce a common expertise (conclusion and summary of

discussions), 4) Realize a briefing note, regarding medical data but also including first

information on risk assessment (population potentially exposed, severity), and

proposals for actions to be taken if necessary. Later on, the goal of this briefing note

could be to share the information with institutions concerned: national agencies, EU-

OSHA. This tool has been successfully tested for the 3 first steps.

Result 3

https://occwatch.anses.fr/

First of all, Data mining tools already used in pharmacovigilance (disproportionality

metrics), have been validated on French RNV3P database and it has been decided to

use them on a routine basis there. They have also been tested on UK THOR data,

showing an interest on these data also (cf extensive STSM report of V Bonneterre on

MODERNET website). One of their limitations is that these methods consider

occupational exposures separately.

For that reason, other methods have been developed (« Exposome » and

« Observational surveillance »), taking into consideration “multi-exposure” (as recorded

into existing databases). These methods have been presented within Modernet

sessions, and also been the subject of STSMs.

Several teams also assessed the interest of GIS (Geographical Information Systems)

in order to combine and analyse occupational health data for surveillance purposes.

One common article is to be submitted, highlighting their interest from “macro” level

(different scales, the biggest one currently being the state’s one) to the micro one

(within companies).

Finally, the Manchester team presented to other partners the value of QSARs for

highlighting Occupational Asthmagens, and conversely, the usefulness of clinical data

to improve QSARs

STSMs

3 STSMs were conducted to help achieve WG3 aims: Stefan Mandic from Milano

(2013) as well as Martin Schouteden from Leuven (2014) went one week in Grenoble

in order to study methods develop their for detecting new emerging issues. Vincent

Bonneterre went 3 months in Manchester (2 months as STSM; 2012) in order to test

disproportionality metrics on UK THOR database, and learn more about as well as

apply QSARs developed by the Manchester team.



- Increase awareness of EU stakeholders of the interest and potential of “alert

systems” relying on medical data (“disease-first approach”) to detect early new

WRD. Especially because we disseminated our achievements not only in scientific

congresses (such as EPICOH Utrecht 2013), but also through EU institution, as for

example at the OccDis conference in Brussels Dec 2013, organised by DG

employment from the EU Commission, or the workshop organised by EU-OSHA in

Oct 2014 in Brussels.

- A proposal for an integrated system of occupational health vigilance inspired from

what is done in Food Safety (EFSA)

WG4: dissemination and implementation of new knowledge on occupational diseases

Leader: Claudio Colosio

Dissemination of the results of the project has been achieved by several passive and active means

Methods The first very important project outcome in the field of active dissemination has been the creation of a project website, at the address: http://www.costmodernet.org/

In the website, two main areas have been created. The first is restricted to the Consortium members for internal users. The second is open to the public to promote the access of a significant number of public and private sector experts, occupational health personnel and stakeholders to the most relevant information regarding the project and its activities as well as to the updated information regarding techniques and practical experiences carried out in the field of research and detection of new and emerging occupational risks and diseases. This project website has been also a unique tool in promoting networking, bridging among different institutions, finding partners for projects as well as for public debates and ‘round tables’.


The website has been such an important and successful experience that it has been decided to maintain it active after the end of the COST action, under the responsibility of the action members.

It is worth underlining that, before the creation of the project’s website and the subsequent opening of the request of registration, this potential large network, strongly linked with timely and urgent EU priorities, did not exist at all. Their registration and the website visits suggest that, around the “first circle” of active subjects (mainly MODERNET consortium members), there is also a larger “second circle” of people interested in the topic and willing to continuously collect updated information on trends of occupational diseases and new and emerging risks and diseases in the European Union.

A second component of active dissemination has been the use of new internet techniques in the enhancement of a rapid exchange of research knowledge and collaboration in research projects through the use of social media. In fact, the Consortium is currently actively present in the most important social networks (Linkedin, Facebook, Twitter, and Research Gate).

Active dissemination has been carried out also through the delivery by senior Action members of specific outreach activities about MODERNET. Such activities have been carried out for non-members of the Action in various countries in particular by the Chairman in Barcelona - November 2012, Rome - November 2012, Bucharest - May 2013, Paris -October 2013.

A more passive dissemination has been carried out through the publication on peer review journals of papers addressing the main aims and objectives of Modernet, for example as a follow up to reported cases of occupational disease developed, delivered and evaluated by Action members (references in added literature list).To make the results of the Action manageable for the practice of prevention, the development of scenarios for monitoring occupational diseases on several levels is necessary. Verma et al. (2002)1 stated that the development of control strategies for occupational hazards takes place at the societal and the local workplace level. These two levels have differing information needs. At the societal level, control measures are usually through regulatory actions on the national level or the industrial sector level. Information is then needed on possible exposure-effect relationships as well as on workplace demographics. At the local workplace level, information is needed on the nature of the hazard, where it is likely to be encountered and the available options for risk reduction. Development of scenarios on three levels is necessary: a national scenario, a scenario for branch or sector approaches, and a scenario for the company level. The basic idea is that monitoring should be linked to preventive measures.

The experiences of passive dissemination of the Consortium will culminate in the realization of two collated sets of publications (besides various individual peer-reviewed articles):

The first, will be a special issue of the peer-reviewed journal “Occupational Medicine” which will tangibly demonstrate both the outputs mentioned in the previous section, and the interdisciplinarity addressed in this section, and mentioned in the Chair’s contribution above.

1 Verma DK, Purdham JT, Roels HA. Translating evidence about occupational conditions into strategies for prevention

Occup Environ Med. 2002 Mar;59(3):205-13; quiz 214.

The second will be the publication of a volume addressed at the main activities and objectives of the network, to realize in the frame of the activities supported by the COST office. It is anticipated that the authoritative findings, validated methods and generalisable recommendations that will result should therefore besides scientific impacts, also have socio-economic impacts – for policy makers wishing to determine the burden of OD, the value of interventions, and the likely emergent threats.

STSMs in the COST Action “MODERNET”

Short-Term Scientific Missions aim at strengthening the Modernet COST Action by

allowing scientists to go to an institution in another COST country to foster collaboration or

to learn new techniques (e.g. trend analysis, GIS,…) for discovering trends in occupational

and work-related diseases and tracing new and emerging risks. In Modernet, STSM’s are

particularly intended for Early Stage Researchers and 2 to 3 times per year a call for

application is launched through the Modernet website. The definition of the term “Early

Stage Researcher” (ESR) is based on the time that elapses between the date of the

PhD/Doctorate (or similar experience) and the date of involvement in the COST Action. If

this time span is less than 8 years, a person fits the definition of an ESR. Periods of career

leave, if any, are added to the 8 year time span. Applications are assessed by the chair,

vice-chair and STSM coordinator.

In the first year (2011) no STSMs took place, although there were two workplace visits by

ESR to one of the participating centres without applying for short term scientific mission.

In 2012, three STSMs have been carried out. The reports are published on the website

under STSMs.

- Andrea Zavadilová (CZ) to Manchester (UK) from 14-06 to 21-06-2012 (Euro 1000): Developing a system of tracing new occupational diseases in the Czech Republic

- Annet Lenderink (Nl) to Trondheim (Norway) from 01-10 to 05-10-2012 (Euro 1000): The use of registries of work-related diseases as sentinel event system to discover new OH risk

- Vincent Bonneterre (Fr) to Manchester (UK) from 02-10 to 30-11-2012 (Euro 2500): Studying the synergies between RNV3P and THOR, and their complementary approaches and methods

In 2013, we reserved a budget for 2 long and 4 short STSMs. A call was launched in

December 2012, June and October 2013. We received 7 applications of which 5 went

through.

- Nataša Janev Holcer (Croatia) to Helsinki (Fi) from 04-03 to 08-03-2013 (Euro 1200): Study the system of diagnostics of occupational diseases, registrations, notification and follow-up of occupational diseases

- Stefan Mandic (It) to Grenoble from 19-10 till 26-10-2013 (Euro 1100): Implementation of the RNV3P methodology for the detection of new risks and diseases in Agriculture

- Gaia Varischi (It) to Amsterdam from 04-11 till 10-11-2013 (Euro 1360): The SIGNAAL system: from the Dutch and Belgian scenario to the Italian agricultural sector

- Stefania Curti (It) to Manchester (UK) from 18-11 to 23-11-2013 (Euro 1600): Application of THOR-GP scheme in other countries

- Lynda Bensefa (Fr) to Manchester from 19-11 till 27-11-2013 (Euro 1400): Comparison of prevention effectiveness of actions in British and French occupational diseases

2 STSMs of Sofie and Michelia have been postponed due to personal reasons.

- Michelia Pilleri (It) to Manchester from 04-03 to 03-06-2013 (Euro 1500): Modify the Thor network to evaluate the real incidence of work related exposure

- Sofie Vandenbroeck (Be) to Grenoble from 13-10 to 26-10-2013 (Euro 2500): Detection of new emerging occupational diseases by using exposome technique

In 2014, we launched a call in January. We received and approved 6 applications. The

following STSMs went through.

- Jill Stocks (UK) to Paris (Fr) from 19-05 to 26-05-2013 (Euro 1000): identify and rank the most frequent OD/exposure combinations occurring within each of the THOR and RNVP3N datasets.

- Madeleine Valenty (Fr) to Manchester (UK) from 02-06 to 06-06-2014 (Euro 800): compare time trends for MSD and work-related mental ill-health in two countries (UK and France), with different occupational health organizations.

- Yuriko Iwatsubo (Fr) to Manchester (UK) from 02-06 to 06-06-2014 (Euro 800): compare the French occupational asthma surveillance programme and the UK THOR programs (SWORD, OPRA).

- Sabira Smaili (Fr) to Manchester (UK) from 02-06 to 20-06-2014 (Euro 2400): analyze time trends of work related mental ill-health and skin diseases reported in the French WRD surveillance programme, according to two statistical approaches: Logistic regression or Poisson regression

- Begoña Martinez-Jarreta (Sp) to Manchester UK from from 19-08 to 26-08-2013 (Euro 1000): study the application of the thor system in the Spanish context to encourage physicians especially GPs (General Practitioners) to report occupational disease voluntarily.

- Martijn Schouteden (Be) to Grenoble (Fr) from 29-09 to 03-10-2014 (Euro: 1100): application of the exposome technique to mine health surveillance data for occupational related diseases.

III Previous scientific reports

Previous Scientific Report extracted from report of period from 9-11-2010 to 30-03-2014

II.A Innovative networking

This COST Action succeeded in setting up, for the first time in the EU, a collaborative network of researchers in the areas of measuring trends in occupational diseases (OD) and in detecting emerging occupational health risks. It established a baseline of the knowledge of the type and quality of relevant extant information amongst the participating states. Furthermore it shared, developed and jointly applied scientific methods for measuring trends, evaluating interventions, and detecting risks amongst the member states.

These methods have been put into practice: 10 countries collaborated, for the first time, in sharing data from their national systems to evaluate and compare trends in the EU. Two countries implemented a common method to evaluate an EU directive on chromate in cement. The evidence demonstrated trends in risks of OD, the value of interventions (including EU directives) on reducing the burden of OD. In these ways and in identifying emerging risks the Action will therefore contribute in achieving socio-economic impact, through providing the knowledge needed to prevent, or at least reduce the risk of, OD. This knowledge has been disseminated (for example most recently at the OccDis conference in Brussels 2013) and is being further disseminated in the peer reviewed literature

Working Group 1 undertook a Cochrane Review entitled “Interventions to increase the reporting of occupational diseases by physicians” which was executed as a direct result of the COST-Action Modernet. The Protocol was published and since then the Review has been submitted to the Cochrane Collaboration. There are no previously published reviews that have evaluated the effect of interventions for increasing the reporting (or reducing the under-reporting) of OD. We expect that effective interventions could be applied to increase the reporting of occupational diseases in different contexts and countries. We are disseminating the information on how this can be done, in the belief that this will strengthen the quality of EU statistics, and will inform policy makers and others on the need to reduce risks.

In spite of early indications that ‘Horizon 2020’ would map out to the COST Action agenda, this has not been evident in the call so far. However other EU funding opportunities and national programme proposals / projects have been pursued.


One of the strengths of MODERNET has been its inter-disciplinarity. Thus for example the work or the 1st working group (WG) on quality of data has relied on close working between physicians, epidemiologists and statisticians amongst others. Thus the quality criteria determined by this WG addressed various issues from medical ones of diagnosis and attribution to statistical ones, and hence in turn underpinned the work of the other WGs. In such a way, WG1 proposed ideas on how to specify the “ideal” register of data regarding OD, how to promote and perform evaluation of effectiveness of interventions to increase OD reporting (new laws or surveillance systems) and how to execute systematic reviews in

the field of aetiology of OD.

Correspondingly WG2 dealing with national trends in WRD and methods for evaluating interventions, was led by statisticians and epidemiologists, but also involved physicians and other occupational health specialists closely involved in ‘making’ the data (i.e. diagnosis) or managing data systems. The data used by this group came from a wide range of agencies – some closely linked with insurance schemes, others linked to national health care provision, while other schemes were totally voluntary. In detecting new hazards, besides medical and toxicology expertise, epidemiology, computer science and occupational hygiene inter-disciplinarity was especially valuable in WG3. Thus WG3 included experts with skills in text mining from the TNO institute (NL) who had previously developed an Emerging Risk Identification Support Service in the field of food safety. The experience of EFSA and their Emrisk unit, dedicated to the detection and expertise of new risks related to food, was also a source of inspiration, as well as other vigilance methods (pharmacovigilance, nutrivigilance). Other output relied on collaboration with experts in Geographic Information Systems or in Quantitative Structure Activity Relationships – important tools in identifying or predicting new OD hazards. Close links with national institutions in charge of health and safety was also essential, notably with ANSES in France who offered a support for the Modernet OccWatch project (mentioned below).

The whole Action worked very coherently both in achieving the above goals and in their final dissemination through working group 4. An incipient special issue of the peer-reviewed journal “Occupational Medicine” will tangibly demonstrate both the outputs mentioned in the previous section, and the inter-disciplinarity addressed in this section. It is anticipated that the authoritative findings, validated methods and generalisable recommendations that will result should therefore besides scientific impacts, also have socio-economic impacts – for policy makers wishing to determine the burden of OD, the value of interventions, and the likely emergent threats.


During the life of the Action from its first launch in November 2010 about fifty additional new members joined. The total number of individual participants involved in the Action work was about 70 at any one time. Of the current 83, there are 35 females (42%) and 24 (29%) Early Stage Researcher (ESR) participants

A key feature of the Action was the active involvement of Early Stage Researchers (ESRs) both in the processes such as networking activities, and in the output including presentations at COST Modernet meetings as well as at other conferences such as the OccDis EU meeting in Brussels in 2013 (the special publication will also demonstrate this). Although none took place in the first year, a total of fourteen STSMs took place during the Action thereafter. A number of STSM participants including ESRs took datasets with them to analyse with the help of staff and methods in the host centre – thus fostering new collaborations which are being translated into scientific publications. Moreover the biannual Action conferences and workshops strongly encouraged and featured presentations by the ESRs guided by their mentors. Therefore in spite of the fact that the budget precluded the organisation of a Training School as such, extensive and very customised and detailed practical training was given to the ESRs.

There were participants from two non-COST Countries approved by the CSO. One from Australia (Prof Malcolm Sim) gave important keynote presentations and engaged in joint

publications (see annex) with Action members. The participant from Albania illustrated the value of the Action in disseminating good practice beyond the EU and eventually presented his surveys at one of the Action conference workshops.

A comprehensive project website with user-interactive functions was set up early in the COST Action: http://www.costmodernet.org/It informed both participants and the wider public about the aims, structure, composition and outputs of the project. It also provided a secure forum for online information sharing, communication and debate between the MODERNET consortium network members. The website was a first very important project outcome, because registration within it collected and made easily accessible a significant number of public and private sector experts, occupational health personnel and stakeholders who have shown interest in our main aims and objectives and are interested in networking. Before the creation of the project’s website and the subsequent opening of the request of registration, this potential large network, strongly linked with timely and urgent EU priorities, did not exist at all. Their registration and the website visits suggest that, around the “first circle” of active subjects (mainly MODERNET consortium members), there is also a larger “second circle” of people interested in the topic and willing to continuously collect updated information on trends of occupational diseases and new and emerging risks and diseases in the Union.

It is also worth mentioning that the Consortium is actively present in the most important social networks (LinkedIn, Facebook, Twitter, and Research Gate). Moreover, specific outreach activities about MODERNET by senior Action members were delivered to non-members of the Action in various countries (e.g. by the Chairman in Barcelona - November 2012, Rome - November 2012, Bucharest - May 2013, Paris -October 2013).

Since the last annual report two Management Committee meetings combined with conferences / workshops have been undertaken (Bucharest - May 2013, Paris -October 2013). They have resulted in tangible interdisciplinary work towards this Cost Action’s dissemination of its scientific results programme in the peer reviewed literature. Thus a special edition of the peer-reviewed journal ‘Occupational Medicine’ will feature this COST Action’s output. Ten publications have been prompted by the Action so far, with a further 12 anticipated in the special edition or elsewhere, although besides these more than a further hundred relevant to the Action’s objectives of identifying new OD or measuring trends in OD incidence have been published by MODERNET members. The list of publications and other outreach activities that resulted from COST networking through the Action is given in the Annex).

Besides the aforementioned activities, various projects have developed between COST network colleagues such as collaborative work between FR-UK, IE-UK, BE-FR-NL, as will be illustrated in the publications and presentations at conferences. Besides the STSMs, further exchanges were fostered especially of ESRs funded by ERASMUS and other sources.

Participation in the Action was either an essential feature (as in the Cochrane project) or an adjuvant asset in members raising research funds; such as €1.8M from UK and IE governmental agencies for measuring trends in OD in those countries. There was also collaboration with various national agencies especially the French Institution (ANSES) supporting the national network for work related disease vigilance and prevention (RNV3P).



In the opinion of the management committee (MC), the main successes of the Action were:

The establishment of a very collegial international and inter-disciplinary network which included Early Stage Researchers as peers, fostered their enthusiasm and supported their training needs within the common purposes mentioned below:

It established and made recommendations on the best means of data collection, taking account of national feasibility, and the standards of the quality of data essential to measure and track trends in the burden of occupational disease in the EU

The Action developed, shared and jointly applied methods to show trends temporal trends in the reported incidence of occupational disease (OD) in Europe

It developed methods to evaluate national or EU level interventions aimed at reducing the risks of OD

MODERNET demonstrated collaboratively and internationally the extent to which interventions (such as EU directives) have been associated with a reduction in the reported incidence of specific occupational disease

It developed and internationally applied methods to identify new ‘signals’ of emerging work related diseases and to help predict new hazards.

It launched a European sentinel clinical watch system (OccWatch project), designed to capture case-reports of potentially new work related diseases, to look for similar cases in other countries, to ensure a common expertise was applied to the cases, and finally to disseminate information to stakeholders when relevant for preventive purposes.

The Action applied a variety of methods (from peer review literature to the Web, and social media) for the continuing dissemination of the above

It identified and made reachable a large network of experts and stakeholders interested in OD trends and new and emerging risks and diseases.

Arguably a drawback of the COST Action is the effort and time involved in the work, especially with Universities often place emphasis on primary hypothesis driven fully externally funded research. Nevertheless we in the MC believe that this COST Action has been an invaluable collaborative opportunity acting as a stepping stone to further international and interdisciplinary collaborations with scientific as well as socio-economic impact.

One hopeful expectation was that the Horizon 2020 document in the year preceding the December 2013 identified the following EU needs of “… improving surveillance and preparedness…. &… improving scientific tools and methods to support policy making and regulatory needs ….” which mapped out remarkably well with the agenda, activity and output of the MODERNET COST Action. However we were frustrated and disappointed, when these terms were not featured in the official H2020 call of December 2013, and hence we are exploring other avenues for further support of the MODERNET agenda. For example the extension of the promising tool “OccWatch” tool beyond Modernet would need support and resources.


II.A. Innovative networking

Innovative knowledge resulting from COST networking through the Action. (Specific examples of Results vs. Objectives)The main results of the previous years are mentioned in the reports underneath.

A comprehensive survey of all members was undertaken to collect information relevant to the overall aims of the Action as well as those of the individual WGs, thus achieving maximal response efficiently and without undue overlap

There has been further improvement and development of the website as an e-platform for exchanges between members, as well as other advances in dissemination [further detailed in Annex 2 below]

In 2012 work commenced in WG1 on a funded Cochrane collaboration with networking of several COST Modernet members towards the aim of determining the best quality methodology for reporting for health surveillance purposes.

Similarly for WG2 a survey collated information in respect of national data collection for compensation purposes, with international collaboration in developing methods to study trends in occupational disease incidence

Networking on methods for identifying new diseases permitted WG3 to develop and pilot a strategy for a Sentinel Clinical Watch System. Moreover in this WG as well, methods developed in one country have been applied to data generated in other countries.

Significant scientific breakthroughs as part of the COST Action. (Specific examples) A joint publication between French and UK teams has been published. It concerns new

methodologies to highlight trends in occupational diseases. (Paris et al. Work-related asthma in France)

Approaches have been developed and applied to investigate in a controlled manner through interrupted time series methods whether interventions at a national level have an influence on occupational disease incidence (Stocks et al, Occupational & Environmental Medicine)

Moreover other presentations at Modernet meetings since then (Manchester, Leuven and Rome have formed the basis of peer reviewed publications in international journals as listed elsewhere in this report]

Tangible medium term socio-economic impacts achieved or expected. (Specific examples) In general: Results, such as measurable effects of preventive measures on

occupational diseases incidence will also deliver important information from a socio-economic point of view. Exchanges on potential new occupational diseases, and identification of new causes of, or circumstances leading to disease should be followed by social benefit following preventive action

Specific Examples: Results presented in WG2 and since published showed how favourable downward trends in occupational disease incidence (asthma and dermatitis) can be demonstrated at a national level following statutory intervention (e.g., following the EU directive on CrVI) or other control measures. Other results accepted for publication and now in press in international journals are addressing whether ’ market forces’ may have an effect on trends in occupational disease incidence (Stocks et al, Occupational & Environmental Medicine).

Spin off of new EC RTD Framework Programme proposals/projects. (List) The Dutch group has acquired research funding from the EU to participate in an

European project on occupational diseases (Occupational Disease Systems in Europe).

The participation in the COST/Modernet Action was a strong decisive factor for acquiring the subsidy. The report of this “Progress project” is published in April 2013: 'Report on the current situation in relation to occupational diseases' systems in EU Member States and EFTA/EEA countries, in particular relative to Commission Recommendation 2003/670/EC concerning the European Schedule of Occupational Diseases and gathering of data on relevant related aspects’ http://ec.europa.eu/social/main.jsp?catId=716&langId=en It is available under 'related documents' in the right-hand side column of the page.

Spin off of new National Programme proposals/projects. (List) UK: Participation in the COST Modernet Action has been cited as an enhancing factor

in the awarding of research funds to support The Health and Occupation Research network (THOR) in the UK [2012-2016] and in the Republic of Ireland [2012-2013]

Netherlands: A pilot project to develop an online tool for reporting new occupational health risks by occupational physicians is funded by the Ministry of Social Affairs and Employment. The project started January 2013 and will be evaluated in 2014. The online tool should be launched in July 2013. In the project there is strong collaboration with Belgium and involvement of COST Action WG3 regarding the Sentinel Clinical Watch System.

Finland: Involvement in the COST Modernet Action has co-influenced some national initiatives such as COPD being proposed to be added to the list of occupational diseases as a compensable disease and set up of a working group on occupational cancer to prepare a recommendation of the most important occupational carcinogens and conditions on which the cancer cases can be accepted as occupational diseases

Czech Republic: Czech participation in COST Action IS1002 gave strong impetus to the Czech national project aimed at the development of the system for detection of new occupational diseases in the Czech Republic. Andrea Zavadilová, M.D., who is in charge of the project, used the advantage of her STSM in Manchester, UK, to learn from experience of UK and France in that matter. Currently, an on-line questionnaire inspired by information from some countries involved in the COST Action is under preparation. The questionnaire is to be filled by general practitioners and other physicians when a patient suspected of new exposure-disease association is presented in their office. The awareness of the reporting physicians will be raised using publication in the journal “General Practitioner” and by oral presentations at various scientific meetings.

Albania: Albanian participation focused on asbestos, with the preparation of a questionnaire addressed at the identification of asbestos contaminated sites in the Country and the asbestos related diseases.

Belgium: Precube project; building a data warehouse for the detection and evaluation of trends of occupational diseases


Additional knowledge obtained from working with other disciplines within the COST framework. (Specific examples) The output exemplified by the publications mentioned in the previous section and these

and others cited in Annex 1 below have all relied upon, and would have not been possible without interdisciplinary working between physicians, epidemiologists, statisticians and others expertise such as hygienists and qualitative research workers. Of note have been the papers on trends in disease incidence, on the evaluation of interventions and in identifying signals suggesting new diseases or new circumstances causing disease

Evaluation of whether the level of inter-disciplinarity is sufficient to potentially provide scientific impacts. (Specific examples)

http://ec.europa.eu/social/main.jsp?catId=716&langId=en

Publication in international journals such as ‘Occupational and Environmental Medicine’ as well as citation of these papers by other scientists confirms the scientific impact of this work

Evaluation of whether the level of inter-disciplinarity is sufficient to potentially provide socio-economic impacts. (Specific examples) In this respect we acknowledge that we have so far inferred a likely impact. We have

however begun liaising with potential partners (whether currently EU funded or not)with disciplinary strengths that are complementary to ours such as risk assessment, health economics etc so as to achieve this aim in the longer term


Additional new members joined the Action during its life:o Ireland, Iceland and FYR of Macedonia joined the Action in 2011; the Institute of

Public Health of Tirana (Albania) was approved as a Non-COST member in 2012.o An expression of interest from a Turkish academic was warmly welcomed by the MC.

This membership is now being pursued through the Turkish national COST representative

o In view of the previous withdrawal of the Spanish MC Representative, extensive consultation within the MC reached a MC consensus on two Spanish academics [in different institutions] who were to be encouraged to seek membership through their national representative. Both Spanish nominees have enthusiastically accepted the opportunity to seek membership.

Total number of individual participants involved in the Action work.o The total number of individual participants involved in the Action work is 63 persons

(36 men (57%) and 27 women (43%)).

Involvement of Early Stage Researchers in the Action, in particular with respect to STSMs, networking activities, and Training Schools. In addition, justification should be provided if less than 4 STSMs were carried out during the year.

o Seventeen early stage researchers are involved in the Action. They actively participate and present orally the work they are involved in by themselves

o Short-Term Scientific Missions aim at strengthening the Modernet COST Action by allowing scientists to go to an institution in another COST country to foster collaboration or to learn new techniques (e.g. trend analysis, GIS,…) for discovering trends in occupational and work-related diseases and tracing new and emerging risks. In Modernet, STSMs are particularly intended for Early Stage Researchers and 2 times per year a call for application is launched. Applications are assessed by the chair, vice-chair and STSM coordinator. So far 3 calls have been launched.

o In 2012, three STSMs have been carried out, all three by Early Stage Researchers (ESR). In brief, Andrea Zavadilová from the Charles University Prague (Czech Republic) visited the Centre for Occupational & Environmental Health In Manchester (United Kingdom). Annet Lenderink (Coronel Institute on Work and Health, Amsterdam, Netherlands) visited the Norwegian Labour Inspection Authority (Trondheim) and the National Institute on Occupational Health (Oslo ) Vincent Bonneterre (Centre of Occupational and Environmental Diseases, Grenoble, France) spend almost three months at the Centre for Occupational & Environmental Health in Manchester (United Kingdom). For additional information Annex 2.

o For 2013, we reserved a budget for 2 long and 4 short STSMs. A call was launched in December, 2012. We received 5 applications of which 4 have been approved (1 long STSM). In the meantime, one STSM has been completed. Dr Nataša Janev Holcer (Department for Occupational and Environmental Health, Zagreb, Croatia) visited the Finnish Institute of Occupational Health in Helsinki Finland. The other 3 STSMs are planned in the second and third trimester of 2013. A new call for STSM will be

launched May 2013.

Involvement of researchers from outside of COST Countries. o Australia and Albania participate in the Action as non-COST country. So, the

percentage of participants from countries with reciprocal agreements is 3%. The representative of Australia is a member of WG1, the representative from Albania is a member of WG3.

Advancement and promotion of scientific knowledge through publications and other outreach activities.

o See Annex 1 for the publications resulting from COST networking through the Action. Furthermore the network promotes its activities by the website of the network. (http://www.costmodernet.org/ and the network started a LinkedIn Group COST Action IS1002 Modernet http://www.linkedin.com/groups?gid=3879948&trk=hb_side_g.

Activities and projects with COST network colleagues.o See Annex 2 for comprehensive the details of the activities and projects in the

Working Groups

The capacity of the Action members to raise research funds.o In 2013 the network will be making plans to raise research funds from Horizon 2020

or other research funding sources.


The main successes of the Action since the start of the third year were:o Modest expansion in membership, but more importantly an active engagement in one

way or another encompassing the whole range of membershipo A significant increase in STSMs and development of young researcherso High quality international peer reviewed papers – some bridging the national

membershipso A comprehensive survey of all members to collect information relevant to the overall

aims of the Action as well as those of the individual WGs Commencing a funded Cochrane collaboration as part of the quality driven agenda of WG1

o A survey on the availability of national data regarding occupational disease compensation, and how these data may be influenced by legislation.

o Further methodological enhancements in evaluating the influence of interventions on trends in incidence of occupational disease (WG2)

o Development and piloting of a strategy for a Sentinel Clinical Watch System for the purposes of picking up early signals of new disease or circumstances causing disease

o Application of methods developed in one country for identifying new disease signals to data collected in other countries

o Further development of the website with public and restricted area for members www.costmodernet.org, and development of other dissemination media such as a Facebook page, LinkedIn group for members and other interested researchers and twitter account @costmodernet

o Developing a strategy for dissemination of joint publications (WG4).

Drawbacks of the Action in 2012:o A drawback identified continues to be to manage the inflating number of participating

countries, when the research input of some/many of them is not so strong. If all expressed interest in Occupational health vigilance, some do not have a research background, and/or did not initiate projects at a national level. This is partly due to


http://www.linkedin.com/groups?gid=3879948&trk=hb_side_g


COST rules (nominations at a national level). However we have begun to be more pro-active in identifying key individuals or active teams in eligible countries whose participation would be of benefit to them as well as strengthening the Modernet collaboration

o Although significant increase in STSMs was evident in the last year when compared to the previous one, effort continues to be needed to encourage STSMs from a wide range of countries especially from younger researchers

o Another remark concerns the administrative duty of COST project that has often distracted the attention of the Grant holder. This administrative burden was probably underestimated.



Innovative knowledge resulting from COST networking through the Action. (Specific examples of Results vs. Objectives)The main results of the 1st year are mentioned in the report hereunder:

To have achieved inter-disciplinary working e.g. between statisticians, epidemiologists and occupational physicians(see below)

Launching of a website with an e-platform for exchanges between members In the aftermath of the international congress “Tracing new occupational diseases” in

April 2011 in Amsterdam, the proceedings were published in an International peer reviewed journal: SH@W Vol. 3, No. 1, Mar. 2012

Significant scientific outputs as part of the COST Action. (Specific examples below) Tangible medium term socio-economic impacts achieved or expected. (Specific examples) Spin off of new EC RTD Framework Programme proposals/projects. (List)

o The Dutch group has acquired research funding from the EU to participate in an European project on occupational diseases (Occupational Disease Systems in Europe). The participation in the COST/Modernet Action was a strong decisive factor for acquiring the subsidy. The report of this “PROGRESS report on the evaluation of Recommendation 2003/670/EC2 concerning the EU schedule of Occupational Diseases” will be presented to the EU in May 2012. in this report there is a Chapter on New occupational health hazards in which the MODERNET COST approach is elucidated. Dr Christa Sedlatschek, the new director of the European Agency in Bilbao reacted very positive when Gert van der Laan presented OHS-vigilance with the MODERNET COST activities in Paris on 15 March 2012 at the conference 'Identifying and recognising occupational diseases in Europe' organized by EUROGIP.

o Unfortunately, an application for a Marie Curie Intra European Fellowship in 2012-2013:” Advanced training & mentorship in Epidemiology and Geographical Information Systems: towards a trans-European GIS application to improve knowledge from Occupational Disease Surveillance Schemes” won’t finally be funded despite its good scientific evaluation (note: 80/100 > cut off 70; one fourth of the eligible projects have been funded)

Spin off of new National Programme proposals/projects. (List)o A project has been submitted at the French level to increase level of information

of all haematopoietic diseases recorded in the RNV3P and apply specific analyses to this database. If not successful, the analyses will be done on the existing data


Additional knowledge obtained from working with other disciplines within the COST framework. (Specific examples in earlier report below)

Evaluation of whether the level of inter-disciplinarity is sufficient to potentially provide scientific impacts. (Specific examples in earlier report below)

Evaluation of whether the level of inter-disciplinarity is sufficient to potentially provide socio-economic impacts. (Specific examples in earlier report below)


Additional new members joining the Action during its life:

o Ireland, Iceland and FYR of Macedonia joined the Action in 2011o The application from the Institute of Public Health of Tirana has not yet been

approved by DC ISCH. The application will be considered for approval by DC ISCH with electronic procedure in the period from April, 20th to May, 4th 2012

o Interest was shown from institutes in Sweden and Slovakia, which we provided with information on how to join the action.

Total number of individual participants involved in the Action work.o The total number of individual participants involved in the Action work is 53 persons

(28 men (53%) and 25 women (47%)). Involvement of Early Stage Researchers in the Action, in particular with respect to

STSMs, networking activities, and Training Schools. In addition, justification should be provided if less than 4 STSMs were carried out during the year.

o Seven early stage researchers are involved in the Action. Two workplace visits have been performed by early stage researchers to one of the participating centres. As a result of starting up the work in 2011, no STSM’s have been carried out. To stimulate STSM’s in 2012, the network has appointed an STSM-coordinator (Prof. Lode Godderis) and WG’s have been asked to provide concrete suggestions for STSM’s in 2012.

o At the latest round of COST Action Workgroup and plenary discussions in Manchester the following STSM expressions of interest were raised and discussed:

2 researchers to go from France to the UK to share experiences on sophisticated statistical methods to analyse trends

1 researcher from the Czech Republic to go to Belgium and the UK to learn methodology on data collection for trends in occupational diseases and identifying new diseases

1 researcher from Italy to go to the UK to undertake a study of occupational disease incidence in specific high risk sectors using comparative data from more than one EU country

Involvement of researchers from outside of COST Countries. o Australia participates in the Action as non-COST country. So, the percentage of

participants from countries with reciprocal agreements is 2%. The representative of Australia is a member of WG1.

Involvement of Early Stage Researchers:o Within the frame of the Modernet activities (as part of collaborations arising from

networking) a junior doctor from the University of Milan will partly be associated, for a six month period, with the activities of the Grenoble’s team.


o See Annex 1 for the publications resulting from COST networking through the Action. Furthermore the network promotes its activities by the website of the network. (http://www.costmodernet.org/ and the network started a linkedin Group COST Action IS1002 Modernet http://www.linkedin.com/groups?gid=3879948&trk=hb_side_g.

Activities and projects with COST network colleagues.o See Annex 2 for the activities and projects in the Working Groups

The capacity of the Action members to raise research funds.o For 2012 the network has the ambition to raise research funds from FP7 or other

research funds.

II.D. Self evaluation

The main successes of the Action since the start of the second year were:o Installation of new Chair (Raymond Agius) and Vice Chair (Annet Lenderink) and

appointment of a STSM coordinator (Lode Godderis) and a new WG leader for WG1 (Stefano Mattioli) to keep the Action moving.

o Meeting of members of WG1 in Paris, writing a Cochrane proposal on the spot.


o Launch of website in January 2012 with public and restricted area for members www.costmodernet.org

o Create LinkedIn group for members and other interested researchers.o Presenting COST Modernet and some of our research in a special session at the 30th

ICOH congress in Cancun Mexico on 20 March 2012o Publishing proceedings and articles presented at the international congress Tracing

New Occupational Diseases in SH@Wo Peer-reviewed publications in other journals (e.g. Occup Env Med) which already

begin to fulfill some of the output targets of COST Modernet Drawbacks of the Action in 2011/2012:

o The main drawback identified is probably to manage the inflating number of participating countries, when the research input of some/many of them is not obvious. Whereas all expressed interest in Occupational health vigilance, some do not have a research background, and/or did not initiate projects at a national level. This is partly due to COST rules (nominations at a national level), but also, we should admit, due to our lack of active “lobbying” on active teams in other countries we would have like to work with. We are working to overcome this shortcoming.





Innovative knowledge resulting from COST networking through the Action. (Specific examples of Results vs. Objectives)

The main results of the 1st year are:1) to have gathered so many different EU partners with interest in occupational diseases around the same focus of occupational vigilance and to understand more deeply what are the specificities and expectations of each member2) to have shared many experiences around this focus, such as, high quality methodological issues designed by some of the participating teams to address occupational vigilance, but also information on potentially new occupational diseases (a more systematic inventory of databases of interest in all participating countries has also started)3) to have built an e-platform for exchanges between members4) to have fixed the work plan of the different groups and the participation of each member in at least one of them. 5) to have organised under the auspices of the Dutch team, an international congress attended by more than hundred international experts on occupational diseases, where the work of Modernet members and other researchers have been presented “Tracing new occupational diseases” in April 2011 in Amsterdam. The scientific quality of the event is confirmed by the publication of the proceeding of the Event in an International peer reviewed journal (in progress at the time of the delivery of this report).

Significant scientific breakthroughs as part of the COST Action. (Specific examples)o A first joint publication between French and UK teams is accepted. It concerns

new methodologies to highlight trends in occupational diseases. Paris et al. Work-related asthma in France: recent trends for the period 2001-2009. The Journal of Allergy and Clinical Immunology

Tangible medium term socio-economic impacts achieved or expected. (Specific examples)o In general: Results, such as measurable effects of preventive measures on

occupational diseases incidence will bear important information also from a socio-economic point of view. Exchanges on potential new occupational diseases, and search of new cases also may bring such information

o Specific Example: Results presented in WG2 showed how favourable downward trends in occupational disease incidence (asthma and dermatitis) can be demonstrated at a national level following statutory intervention (e.g., following EU directive on CrVI) or other control measures

Spin off of new EC RTD Framework Programme proposals/projects. (List)o The Dutch group has acquired research funding from the EU to participate in an

European project on occupational diseases (Occupational Disease Systems in Europe). The participation in the COST/Modernet Action was a strong decisive factor for acquiring the subsidy.

o Eligible Application for a Marie Curie Intra European Fellowship in 2012-2013: Project O2DS” Advanced training & mentorship in Epidemiology and Geographical Information Systems: towards a trans-European GIS application to improve knowledge from Occupational Disease Surveillance Schemes” (note: 80/100 > cut off 70; final Decision not known at the time being. About one fourth of the eligible projects will be funded)

Spin off of new National Programme proposals/projects. (List)o A project has been submitted at the French level to increase level of information

of all haematopoietic diseases recorded in the RNV3P and apply specific

analyses to this database. If not successful, the analyses will be done on the existing data


Additional knowledge obtained from working with other disciplines within the COST framework. (Specific examples)

o Most of the Modernet forces come from disciplines with interest in occupational health (Occupational Diseases specialists, OD researchers especially epidemiologists, hygienists and labour inspectors), enriched with some scientists with fundamental background in statistics, mathematics or modelisation especially. This allows studying the opportunity of more complex techniques. Some of us notably the French workers also develop expertise in Geographical Information Systems.

o Finally one of our member is a policy maker (J Costa David, EU commission), and The Netherlands and Spain have skills in IT-technologies (web)

Evaluation of whether the level of inter-disciplinarity is sufficient to potentially provide scientific impacts. (Specific examples)

o As shown by the first publications, inter-disciplinarity is one of the key points that allows scientific breakthroughs (multi exposure analyses, QSARs, new methodologies for trends, GIS). This inter-disciplinarity is maybe not sufficiently represented and shared, as few participating teams benefit from researchers with this backgroundNote: QSAR (Quantitative Structure Activity Relationship) development in occupational diseases (notably occupational asthma) can be limited since data for the ‘learning set’ can only arise out of actual occupational disease cases (as the data cannot be generated in experimental animals nor volunteers). The COST action (especially working group 3) has presented a platform for such new case data originating from the participating EU states to be provided to chemists, immunologists and clinicians working on QSAR development and evaluation (e.g. Seed et al from the UK team)

Evaluation of whether the level of inter-disciplinarity is sufficient to potentially provide socio-economic impacts. (Specific examples)

o On the other hand, we think our level of inter-disciplinarity focused on diagnosing, taking care and preventing occupational diseases, is sufficient to help provide information with socio economic impacts


Additional new members joining the Action during its life:o Ireland, Iceland, and Macedonia entered the network after its start in November 2011.

Albania has applied for membership. Total number of individual participants involved in the Action work.

o The total number of individual participants involved in the Action work is 49 persons (25 men (51%) and 24 women (49%)).

Involvement of Early Stage Researchers in the Action, in particular with respect to STSMs, networking activities, and Training Schools. In addition, justification should be provided if less than 4 STSMs were carried out during the year.

o Five early stage researchers are involved in the Action. Two workplace visits have been performed by early stage researchers to one of the participating centres. As a result of starting up the work in 2011, no STSM’s have been carried out. To stimulate STSM’s in 2012, the network will appoint an STSM-coordinator and WG’s have been asked to provide concrete suggestions for STSM’s in 2012.

o At the latest round of COST Action Workgroup and plenary discussions in

Manchester the following STSM expressions of interest were raised and discussed: 2 researchers to go from France to the UK to share experiences on

sophisticated statistical methods to analyse trends 1 researcher from the Czech Republic to go to Belgium and the UK to learn

methodology on data collection for trends in occupational diseases and identifying new diseases

1 researcher from Italy to go to the UK to undertake a study of occupational disease incidence in specific high risk sectors using comparative data from more than one EU country

Involvement of researchers from outside of COST Countries. o Australia participates in the Action as non-COST country. So, the percentage of

participants from countries with reciprocal agreements is 2%. The representative of Australia is a member of WG1.

Involvement of Early Stage Researchers:o In the frame of the Modernet activities it has been organized a stage of a junior doctor

of the University of Milan who will partly be associated, for a six month period, to activities of the Grenoble’s team.


o See Annex 1 for the publications resulting from COST networking through the Action. Furthermore the network promotes its activities by the website of the network. (http://demo2.costmodernet.org/ and the network started a linkedin Group COST Action IS1002 Modernet http://www.linkedin.com/groups?gid=3879948&trk=hb_side_g.

Activities and projects with COST network colleagues.o See Annex 2 for the activities and projects in the Working Groups

The capacity of the Action members to raise research funds.o For 2012 the network has the ambition to raise research funds from FP7 or other

research funds.

II.D. Self evaluation

The main successes of the Action in 2011 were:o The establishment of a group of nearly 50 persons with expertise on occupational

diseases, which generated very interesting discussions on how to improve monitoring occupational diseases, analyzing trends, tracing new occupational risks and distribution of knowledge on the issue. Furthermore getting acquainted with the work of colleagues by the presentations during the meetings in Amsterdam and Manchester has been very stimulating scientifically.

o The activities of the WGs are described in annex 2. Working plans have been made for 2012.

o Finally the development (officially launched January 2012) of an own network website and a LinkedIn group is a success.

Drawbacks of the Action in 2011:o The main drawback identified is probably to manage the inflating number of

participating countries, when the research input of some/many of them is not obvious. If all expressed interest in Occupational health vigilance, some do not have a research background, and/or did not initiate projects at a national level. This is partly due to COST rules (nominations at a national level), but also, we should admit, due to our lack of active “lobbying” on active teams in other countries we would have like to work with.




Annex of COST Action references 1.

Papers which the Action helped significantly in / which might not have happened without the action (including any provisionally accepted)

Agius R, Bonneterre V, Sim M. What do surveillance schemes tell us about occupational diseases? Chapter 11 p131-141 in Current Topics in Occupational Epidemiology. 288p. Editeur Katherine Venables. Oxford University Press. Oxford, August 2013 ISBN: 9780199683901 Current Topics in Occupational Epidemiology

Le Barbier M, Bonneterre V, Ameille J, Telle Lamberton M, Lasfargues G. (2012) Le Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (rnv3p) : structure du réseau et organisation de l’émergence clinique. Arch. Mal. Prof. Env 73(3), 413-415

Bonneterre V, Telle Lamberton M. (2012) Surveillance épidémiologique et vigilance en milieu professionnel : place du réseau Européen MODERNET (Occupational health vigilance: role of the European Network MODERNET). Arch. Mal. Prof. Env 73(3), 419-421

Bonneterre V. (2013) “What really stands beyond the numbers?”: Diseases and the social construction of Disease. Occup Environ Med 70, 437–438. (Invited Commentary related to Carder M et al. (2013) Time trends in the incidence of work-related mental ill-health and musculoskeletal disorders in the UK. Occup Environ Med 70, 317–24)

Carder M, Mattioli S, Bensefa-Colas L, Stikova E, Noone P, Samant Y, Sludds K, Valenty M, Wannag A, Telle-Lamberton M. A review of the occupational disease monitoring systems in the Modernet consortium. (In preparation)

Curti S, Sauni R, Spreeuwers D, De Schryver A, Valenty M, Riviere S, Mattioli S. Interventions to increase the reporting of occupational diseases by physicians. Cochrane review (submitted).

Mattioli S, Sauni R, Spreeuwers D, De Schryver A, Valenty M, Rivière S, Curti S. Interventions to increase the reporting of occupational diseases by physicians (Protocol). Cochrane Database Syst Rev. 2013;(1):CD010305.

Mattioli S, Gori D, Di Gregori V, Ricotta L, Baldasseroni A, Farioli A, Zanardi F, Galletti S, Colosio C, Curti S, Violante FS. (2013) PubMed search strings for the study of agricultural workers' diseases. Am J Ind Med 56(12), 1473-81.

Money A, Carder M, Noone P, Bourke J, Hayes J, Turner S, Agius R, Work-related ill-health: Republic of Ireland, Northern Ireland, Great Britain 2005–2012 Occupational Medicine Advance Access published October 16, 2014

Paris C, Ngatchou-Wandji J, Luc A, McNamee R, Bensefa-Colas L, Larabi L, Telle-Lamberton M, Herin F, Bergeret A, Bonneterre V, Brochard P, Choudat D, Dupas D, Garnier R, Pairon JC, Agius R , Ameille J, the members of the RNV3P. (2012) Work-related asthma in France: recent trends for the period 2001-2009. Occup Environ Med 69(6), 391-397.

Stocks SJ, McNamee R et al. Trends in incidence of occupational diseases across 10

https://webmail.chu-grenoble.fr/owa/redir.aspx?C=d17dbf41c46a4e2590191976031b82c7&URL=http%3A%2F%2Fukcatalogue.oup.com%2Fproduct%2Facademic%2Fmedicine%2F9780199683901.do%23.UW_Hff9wZQs

European Countries (2000-2012). Under review (Occup Environ Med)

2. Other papers that are related to the Modernet agenda (including any provisionally accepted)

Aalto-Korte K, Henriks-Eckerman ML, Kuuliala O, Jolanki R. (2010) Occupational methacrylate and acrylate allergy - cross-reactions and possible screening allergens. Contact Dermatitis 63(6), 301-312.

Aalto-Korte K, Pesonen M, Kuuliala O, Alanko K, Jolanki R. (2010) Contact allergy to aliphatic polyisocyanates based on hexamethylene-1,6-diisocyanate (HDI). Contact Dermatitis 63(6), 357-63.

Aalto-Korte K, Suuronen K, Kuuliala O, Henriks-Eckerman M, Jolanki R. (2012) Occupational contact allergy to monomeric isocyanates. Contact Dermatitis 67(2), 78-88.

Aalto-Korte K. (2013) Contact allergy from metal-working fluid traced to tall oil fatty acids monoethanolamide. Contact Dermatitis 69(5), 261-322.

Aalto-Korte K. (2013) Occupational contact allergy to the epoxy methacrylate 2,2-bis[4-(2-methacryloxyethoxy)phenyl] propane in an anaerobic glue. Contact Dermatitis 68(5), 314-315.

Ackermann L, Aalto-Korte K, Alanko K, Hasan T, Jolanki R, Lammintausta K, Lauerma A, Laukkanen A, Liippo J, Riekki R, Vuorela AM, Rantanen T. (2011) Contact sensitization to methylisothiazolinone in Finland - a multicentre study. Contact Dermatitis 64(1), 49-53.

Airaksinen L, Pallasaho P, Voutilainen R, Pesonen M. (2013) Occupational rhinitis, asthma, and contact urticaria caused by hydrolyzed wheat protein in hairdressers [letter]. Ann Allergy Asthma Immunol 111(6),577-9.

Barbieri MT, Cocco ME, Cocco P. (2013) Prevalence of atopy in occupational allergic contact dermatitis: comparison of diagnostic techniques. Med Lav 104, 460-466. [in Italian]

Bensefa-Colas L, Telle-Lamberton M, Paris C, Faye S, Stocks JS, Luc A, Bourrain J_L, M.-N. Crépy, D. Dupas, P. Frimat, R. Garnier, M.-P. Lehucher-Michel, J.-C. Pairon, J.-M. Soulat, G.Lasfargues, D. Choudat, the members of the RNV3P and I. Momas. Occupational allergic contact dermatitis and major allergens in France: temporal trends for the period 2001-2010. BDJ 2014.

Béranger R, Hoffman P, Christin-Maitre S, Bonneterre V. (2012) Occupational exposures to chemicals as a possible etiology in premature ovarian failure: a critical analysis of the literature. Reprod Toxicol 33(3), 269-279.

Bonneterre V, Bicout DJ, de Gaudemaris R, on behalf of the RNV3P. (2012) Application of Pharmacovigilance methods in Occupational Health Surveillance. Safety and Health at Work (SH@W) 3(2), 92-100.

Bonneterre V, Faisandier L, Bicout DJ, Bernardet C, Piollat J, Ameille J, De Clavière C, Aptel M, Lasfargues G, de Gaudemaris R, RNV3P. (2010) Programmed health surveillance and detection of emerging diseases in occupational health: contribution of the French national occupational disease surveillance and prevention network (RNV3P).

Occup Environ med 67(3), 178-186

Brandi G, Di Girolamo S, Farioli A, de Rosa F, Curti S, Pinna AD, Ercolani G, Violante FS, Biasco G, Mattioli S. (2013) Asbestos: a hidden player behind the cholangiocarcinoma increase? Findings from a case-control analysis. Cancer Causes Control 24(5), 911-8.

Campagna M, Satta G, Flore V, Ibba A, Meloni M, Tocco MG, Atzeri S, Avataneo G, Flore C, Campo L, Fustinoni S, Bertazzi P, Cocco P. (2011) Use of urinary benzene in biomonitoring low level environmental exposure. G Ital Med Lav Ergon 33(3 suppl), 39-42. [in Italian]

Campagna M, Virgola P, Tamponi M, Casu A, Piquereddu C, Doro M, Manconi D, Demurtas A, Setzu D, DelRio A, Cocco P, Flore C, Meloni M. (2011) Health surveillance among hospital workers exposed to biological agents transmissible via blood in three Italian hospitals. G Ital Med Lav Ergon 33 (3 suppl)1:282. [in Italian]

Campagna M, Satta G, Campo L, Flore V, Ibba A, Meloni M, Tocco MG, Avataneo G, Flore C, Fustinoni S, Cocco P. (2012) Biological monitoring of low-level exposure to benzene. Med Lav 103, 338-46.

Carder M, Money A, Turner S and Agius RM. Estimated incidence rates of work-related illness for GB occupational physicians. Occup Med. In press

Carder M, McNamee R, Turner S, Hodgson J, Holland F, Agius RM. (2013) Time trends in the incidence of work-related mental ill-health and musculoskeletal disorders in the UK. Occup Environ Med 70, 317-324.

Carder M, McNamee R, Turner S, Hussey L, Money A and Agius RM. (2011) Improving estimates of incidence of specialist diagnosed, work-related respiratory and skin disease in Great Britain. Occupational Medicine 61(1), 33-39

Cocco P. (2011) Retrospective assessment of occupational exposures: principles and methods. G Ital Med Lav Ergon 32(4 Suppl), 292-4. [in Italian]

Cocco P. (2011) Silica and lung cancer: state of the art, practical implications and future research. Foreword. Med Lav 102:307-9.

Cocco P. (2011) Silica and lung cancer. What next? Med Lav 102, 368-9.

Cocco ME, Scanu V, Barbieri MT, Cocco P. (2011) Occupational respiratory allergy: a descriptive analysis and agreement between diagnostic tests. G Ital Med Lav Ergon 33/3suppl, 1-299. [in Italian]

Cocco P, Satta G, D'Andrea I, Nonne T, Udas G, Zucca M, Mannetje AT, Becker N, Sanjosé SD, Foretova L, Staines A, Maynadié M, Nieters A, Brennan P, Ennas MG, Boffetta P. (2013) Lymphoma risk in livestock farmers: Results of the Epilymph study. Int J Cancer 132, 2613-8

Cocco P, Satta G, Dubois S, Pili C, Pilleri M, Zucca M, 't Mannetje AM, Becker N, Benavente Y, de Sanjosé S, Foretova L, Staines A, Maynadié M, Nieters A, Brennan P, Miligi L, Ennas MG, Boffetta P. (2013) Lymphoma risk and occupational exposure to pesticides: results of the Epilymph study. Occup Environ Med 70, 91-8.

Cocco P, Vermeulen R, Flore V, Nonne T, Campagna M, Purdue M, Blair A, Monnereau A, Orsi L, Clavel J, Becker N, de Sanjosé S, Foretova L, Staines A, Maynadié M, Nieters A, Miligi L, 't Mannetje A, Kricker A, Brennan P, Boffetta P, Lan Q, Rothman N. (2013) Occupational exposure to trichloroethylene and risk of non-Hodgkin lymphoma and its major subtypes: a pooled InterLymph analysis. Occup Environ Med 70, 795-802

Curti S, Coggon D, Baldasseroni A, Cooke RM, Fresina M, Campos EC, Semeraro F, Zanardi F, Farioli A, Violante FS, Mattioli S. (2014) Incidence rates of surgically treated rhegmatogenous retinal detachment among manual workers, non-manual workers and housewives in Tuscany, Italy. Int Arch Occup Environ Health 87(5), 539-45

Désiron HA, Donceel P, Godderis L, Van Hoof E, de Rijk A. What is the value ofoccupational therapy in return to work for breast cancer patients? A qualitative inquiry among experts. Eur J Cancer Care (Engl). 2014 Jun 25. doi:10.1111/ecc.12209. [Epub ahead of print] PubMed PMID: 24961966.

Dik, S., Scheepers, P., Godderis, L. (2012). Effects of environmental stressors on histone modifications and their relevance to carcinogenesis: A systematic review. Critical Reviews in Toxicology 42(6), 491-500.

Ding Hebo, Solovieva S, Vehmas T, Takala E, Leino-Arjas P. (2010) Hand osteoarthritis and pinch grip strength among middle-aged female dentists and teachers. Scandinavian Journal of Rheumatology 39(1), 84-7.

Erren TC, Morfeld P, Glende CB, Piekarski C, Cocco P. (2011) Meta-analyses of published epidemiological studies, 1979-2006, point to open causal questions in silica-silicosis-lung cancer research. Med Lav 102, 321-35.

Espinosa A, Zock JP, Benavente Y, Boffetta P, Becker N, Brennan P, Cocco P, Foretova L, Maynadié M, Staines A, Nieters A, Kogevinas M, de Sanjose S. (2013) Occupational exposure to immunologically active agents and risk for lymphoma: The European Epilymph case-control study. Cancer Epidemiol 37, 378-84.

Faisandier L, Bonneterre V, de Gaudemaris R, Bicout DJ. (2011) A network-based approach for surveillance of occupational health exposures. J Biomed Inform 44(4), 545-52.

Farioli A, Mattioli S, Quaglieri A, Curti S, Violante FS, Coggon D. (2014) Musculoskeletal pain in Europe: the role of personal, occupational, and social risk factors. Scand J Work Environ Health 40(1):36-46.

Fenclová, Z., Urban, P., Brhel, P. (2010). Occupational Diseases in the Czech Republic in 2009 (in Czech), Pracovní lékařství 62, 74-78

Fenclová, Z., Urban, P., Pelclová, D., Havlová, D., Čerstvá M. (2011). Occupational Diseases in the Czech Republic in 2010 (in Czech), Praktický lékař 91, 263-268

Fenclová, Z., Urban. P., Pelclová, D., Voříšková, M., Havlová, D. (2012). Occupational Diseases in the Czech Republic in 2011 (in Czech), Praktický lékař 92, 214-220

Fenclová Z., Urban P., Pelclová D., Voříšková M., Havlová D. (2013) Occupational

Diseases in the Czech Republic in 2012 (in Czech), Praktický lékař 93, 93-99

Ferri GM, GuastadisegnoCM, Romano GF, Schiavulli N, Palma M, Martino T, Buononato V, Specchia G, Giordano AM, Perrone T, Romano R, Intranuovo G, Musti M, Vimercati L, Mazza P, Strusi M, Antonucci R, Palumbo N, Bertetti V, Satta G, Zucca M, Cocco P. (2011) Occupational exposure to solvents as a risk factor for Diffuse large B-cell lympyhoma. G Ital Med Lav Ergon 33/3suppl 1, 57-58. [in Italian]

Furu H, Sainio M, Hyvärinen H, Akila R, Bäck B, Uuksulainen S, Kaukiainen A. (2012) Detecting chronic solvent encephalopathy in occupations at risk. Neurotoxicology 33(4), 734-41.

Godderis L, Johannik K, Mylle G, Bulterys S, Moens G. Epidemiological andperformance indicators for occupational health services: a feasibility study inBelgium. BMC Health Serv Res. 2014 Sep 19;14:410. doi: 10.1186/1472-6963-14-410. PubMed PMID: 25236590.

Godderis, L., Thomas, R., Hubbard, A., Tabish, A., Hoet, P., Zhang, L., Smith, M., Veulemans, H., McHale, C. (2012). Effect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cells. PLoS One, 7 (6), art.nr. e39205.

Godderis, L., Maertens, N., de Gelder, V., De Lamper, A., De Ruyck, K., Vernimmen, M., Bulterys, S., Moens, G., thierens, H., Viaene, M. (2010). Genetic susceptibility in solvent induced neurobehavioral effects. Neurotoxicity Research 17 (3), 268-278.

Godderis, L., De Raedt, K., Tabish, A., Poels, K., Maertens, N., De Ruyck, K., Bulterys, S., Thierens, H., Viaene, M. (2012). Epigenetic changes in lymphocytes of solvent-exposed individuals. Epigenomics 4(3), 269-277.

Godderis, L., Dours, G., Laire, G., Viaene, M. (2011). Sleep apnoeas and neurobehavioral effects in solvent exposed workers. International Journal of Hygiene and Environmental Health 214(1), 66-70.

Hannu T, Piirila Päivi, Riihimäki Vesa. (2012) Reactive airways dysfunction syndrome from acute inhalation of a dishwasher detergent powder. Canadian Respiratory Journal 19(3), e25-8.

Hannu T, Riihimäki V, Piirilä P. (2009) Reactive airway dysfunction syndrome (RADS) in a chemistry teacher induced by fumes of mixed iodine compounds. Ind Health 47(6), 681-4.

Hannu T, Suuronen K, Aalto-Korte K, Alanko K, Luukkonen R, Järvelä M, Jolanki R, Jaakkola M. (2013) Occupational respiratory and skin diseases among Finnish machinists: findings of a large clinical study. Int Arch Occup Environ Health 86(2), 189-97.

Helaskoski E, Suojalehto H, Virtanen H, Airaksinen L, Kuuliala O, Aalto-Korte K, Pesonen M. (2014) Occupational asthma, rhinitis, and contact urticaria caused by oxidative hair dyes in hairdressers. Annals of Allergy, Asthma & Immunology 112(1), 46-52.

Hussey L, Carder M, Money A, Turner S and Agius RM. (2013) Comparison of work-related ill-health data from different GB sources Occup Med 63(1), 30-37

Hussey L, Turner S, Thorley K, McNamee R and Agius RM. (2012) Work-related sickness

absence as reported by general practitioners in the UK. Occupational Medicine 62(2): 105-11

Hussey L, Turner S, Thorley K, McNamee R and Agius RM. (2010) Survellance of work-related ill-health; a comparison of occupational physicians and general practitioners. Occupational Medicine 60(4), 294-300

Kauppi P, Hannu T, Helaskoski E, Toivio P, Sauni R. (2011) Short-term outcome of occupational asthma in a Finnish population. Clinical Respiratory Journal 5(3), 143-9.

Karvala K, Nordman H, Luukkonen R, Uitti J. (2014) Asthma related to workplace dampness and impaired work ability. Int Arch Occup Environ Health 87(1), 1-11.

Karvala K, Toskala E, Luukkonen R, Lappalainen S, Uitti J, Nordman H. (2010) New-onset adult asthma in relation to damp and moldy workplaces. Int Arch Occup Environ Health 83(8):11.

Karvala K, Toskala E, Luukkonen R, Uitti J, Lappalainen S, Nordman H. (2011) Prolonged exposure to damp and moldy workplaces and new-onset asthma. Int Arch Occup Environ Health 84(7):713-21.

Karvala K, Uitti J, Luukkonen R, Nordman H. (2013) Quality of life of patients with asthma related to damp and moldy work environments. Scand J Work Environ Health 39(1), 96-105.

Keski-Säntti P, Kaukiainen A, Hyvärinen HK, Sainio M. (2010) Occupational chronic solvent encephalopathy in Finland 1995-2007: incidence and exposure. Int Arch Occup Environ Health 83(6), 703-12.

Ketterer F, Symons L, Lambrechts MC, Mairiaux P, Godderis L, Peremans L,Remmen R, Vanmeerbeek M. What factors determine Belgian general practitioners'approaches to detecting and managing substance abuse? A qualitative study basedon the I-Change Model. BMC Fam Pract. 2014 Jun 14;15:119. doi:10.1186/1471-2296-15-119. PubMed PMID: 24927958; PubMed Central PMCID:PMC4064261.

Klasan, Antonio; Madžarac, Goran; Milošević, Milan; Mustajbegović, Jadranka; Keleuva, Slobodanka. (2013) Predictors of lower work ability among emergency medicine employees: the Croatian experience. Emergency medicine journal 30(4), 275-280

Kuijer PPFM, Molen HFvd, Schop A, Moeijes F, Frings-Dresen MHW, Hulshof CTJ. Annual incidence of non-specific low back pain as an occupational disease attributed to whole body vibration according the National Dutch Register 2005-2012. Under review.

Kukkonen MK, Hämäläinen S, Kaleva S, Vehmas T, Huuskonen MS, Oksa P, Vainio H, Piirilä P, Hirvonen A. (2011) Genetic susceptibility to asbestos related fibrotic pleuropulmonary changes. European Respiratory Journal 38(3), 672-678.

Kukkonen MK, Vehmas T, Piirilä P, Hirvonen A. (2014) Genes involved in innate immunity associated with asbestos-related fibrotic changes. Occup Environ Med 71(1), 48-54.

Kwok C, Money A, Carder M, Turner S, Agius RM, Orton D, and Wilkinson M.

Occupational disease in Beauticians reported to The Health and Occupation Research (THOR) network from 1996 to 2011. Clinical and Experimental Dermatology. In press

Janev Holcer, Nataša; Maričević, Marija; Miočić-Juran, Anamarija. (2012)The Use of Mercury-Based Metric Devices Across Croatian Healthcare Facilities. Arhiv za higijenu rada I toksikologiju 63(1), 41-47

Janssen, B., Godderis, L., Pieters, N., Poels, K., Kicinski, M., Cuypers, A., Fierens, F., Penders, J., Plusquin, M., Gyselaers, W., Nawrot, T. (2013). Placental DNA hypomethylation in association with particulate air pollution in early life. Particle and Fibre Toxicology 10(22), 1-11

Laan G van der. (2011) Tracing new occupational diseases in nano-workers. Journal of biomedical nanotechnology 7(1), 18

Laan G van der. (2012) Tracing new occupational diseases, an introduction. Saf Health Work 3(1), 50-1

Laan G van der et al. Chapter 6 New Occupational Hazards in: European Commission 'Report on the current situation in relation to occupational diseases' systems in EU Member States and EFTA/EEA countries’ March 2013.

Laštovková A, Fenclová Z, Bonneterre V Pelclová D. Asthma caused by potassium aluminum tetrafluoride. Manuscript ready to be sent asap to Industrial Health.

Lauby-Secretan B, Loomis D, Grosse Y, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Baan R, Mattock H, Straif K, Cogliano VJ, Aronson K, Tryphonas H, Guo YL, Machala M, Bonefeld-Jørgensen EC, Vorkamp K, Cravedi JP, Le Bizec B, Narbonne JF, Esch H, Cocco P, Merletti F, Vermeulen R, Agudo A, Johansson N, Fiedler H, Hopf N, Glauert HP, Herbert RA, James MO, Ludewig G, Robertson L, Ruder A, Walker N. (2013) Carcinogenicity of polychlorinated biphenyls and polybrominated biphenyls. Lancet Oncol 14, 287-8.

Lehto M, Airaksinen L, Puustinen A, Tillander S, Hannula S, Nyman T, Toskala E, Alenius H,. (2010) Thaumatin-like protein and baker's respiratory allergy. Ann Allergy Asthma Immunol 104(2), 139-46. Leivo-Korpela S, Lehtimäki L, Nieminen R, Oksa P, Vierikko T, Järvenpää R, Uitti J, Moilanen E. (2012) Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers. Respiratory Medicine 106(10), 1435-40.

Annet F Lenderink, Ilona Zoer, Henk F van der Molen, Dick Spreeuwers, Monique H W Frings-Dresen, Frank J H van Dijk (2011) Review on the validity of self-report to assess work-related diseases. International Archives of Occupational and Environmental Health 85(3), 229-51.

Lindström I, Suojalehto H, Henriks-Eckerman M, Suuronen K. (2013) Occupational asthma and rhinitis caused by cyanoacrylate based eyelash extension glues. Occupational Medicine 63(4), 294-7.

Mäkelä R, Kauppi Paula, Suuronen K, Tuppurainen M, Hannu T. (2011) Occupational asthma in professional cleaning work: clinical study. Occupational Medicine 61, 121–126.

Mattioli S, Curti S, De Fazio R, Cooke RMT, Zanardi F, Bonfiglioli R, Farioli A, Violante FS. (2012) Occupational lifting tasks and retinal detachment in non-myopics and myopics: extended analysis of a case-control study. Saf Health Work 3(1), 52-7.

Mattioli S, Zanardi F, Baldasseroni A, Schaafsma F, Cooke RM, Mancini G, Fierro M, Santangelo C, Farioli A, Fucksia S, Curti S, Violante FS, Verbeek J. (2010) Search strings for the study of putative occupational determinants of disease. Occup Environ Med 67(7), 436-43.

McNamee R, Chen Y, Hussey L, and Agius RM. (2010) Randomised Controlled Trial comparing time-sampled versus continuous time reporting for measuring incidence. Epidemiology 21(3), 376-378

Meloni M, Setzu D, Del Rio A, Campagna M, Cocco P. (2013) QTc interval and electrocardiographic changes by type of shift work. Am J Ind Med 56, 1174-9.

Meloni M, Setzu D, Del Rio A, Cocco P. Continuous vocational training and its effects on work ability. In: Nygard C-H, Savinainen M, Kirsi T, Lumme-Sandt K (eds). Age management during the Life Course. Proceedings of the 4 th Symposium on Work Ability. Tampere, Finland: Tampere University press, 2011, pp 336-341.

Meloni M, Daga F, Del Rio A, Setzu D, Campagna M, Miazzi G, Cocco P. (2011) The work capacity index and its applciation in hospital workers. G Ital Med Lav Ergon 33/3suppl 1:294. [in Italian]

Meloni M, Miazzi G, Campagna M, Del Rio A, Daga F, Setzu D, Pilleri M, Cocco P. (2011) Shiftwork: effects on human health and work organization in various industries. G Ital Med Lav Ergon 33/3suppl 1:376. [in Italian].

Miligi L, Benvenuti A, Mattioli S, Salvan A, Tozzi GA, Ranucci A, Legittimo P, Rondelli R, Bisanti L, Zambon P, Cannizzaro S, Kirchmayer U, Cocco P, Celentano E, Assennato G, Merlo DF, Mosciatti P, Minelli L, Cuttini M, Torregrossa V, Lagorio S, Haupt R, Risica S, Polichetti A; SETIL Working Group, Magnani C (2013). Risk of childhood leukaemia and non-Hodgkin's lymphoma after parental occupational exposure to solvents and other agents: the SETIL Study. Occupational and Environmental Medicine. 70(9), 648-55

Miedema HS, Molen HFvd, Kuijer PPFM, Koes BW, Burdorf A. Incidence of low back pain related occupational diseases in the Netherlands. European Journal of Pain, published online. doi:10.1002/j.1532-2149.2013.00430.x

Miranda H, Kaila-Kangas L, Heliövaara M, Leino-Arjas P, Haukka E, Liira J, Viikari-Juntura E. (2010) Musculoskeletal pain at multiple sites and its effects on work ability in a general working population. Occupational and Environmental Medicine 67(7), 449-455.

Molen HFvd, Kuijer PPFM, Smits PBA, Schop A, Moeijes F, Spreeuwers D, Frings-Dresen MHW (2012). Annual incidence of occupational diseases in economic sectors in the Netherlands. Occupational and Environmental Medicine 69(7), 519-521.

Money A, Carder M, Turner S and Agius RM. (2011) Incidence of work-related occupational hearing loss in the UK: OSSA. Occupational Medicine 61(4), 226-233

Money A, Hussey L, Thorley K, Turner S and Agius RM. (2010) Work-related sickness

absence negotiations: general practitioners' qualitative perspective. British Journal of General Practice 60(579), 721-8.

Mullie, P., Godderis, L., Clarys, P. (2012). Determinants and nutritional implications associated with low-fat food consumption. Appetite 58(1), 34-38.

Nakládalová, M., Ehler, E., Urban, P. (2010). Occupational Damage to the Ulnar Nerve at the Elbow Region (in Czech), Čs. Neurol. Neurochir. 73/106: S93

Nakládalová, M., Ehler, E., Pelclová, D., Urban, P. et al. (2013). Low Back Pain as an Occupational Disease (in Czech), Čs. Neurol. Neurochir. 76/109: S44-45

Pelclová, D., Fenclová, Z., Urban, P. (2011). Occupational cancer in the Czech Republic – The tip of the iceberg? Eur. J. Oncol. 16: 149-161

Perrotta C, Staines A, Codd M, Kleefeld S, Crowley D, T Mannetje A, Becker N, Brennan P, Sanjosé S, Foretova L, Maynadié M, Nieters A, Boffetta P, Cocco P. (2012) Multiple Myeloma and lifetime occupation: results from the EPILYMPH study. J Occup Med Toxicol 7:25. Perrotta C, Kleefeld S, Staines A, Tewari P, De Roos AJ, Baris D, Birmann B, Chiu B, Cozen W, Becker N, Foretova L, Maynadié M, Nieters A, de Sanjosé S, Miligi L, Seniori Costantini A, Purdue M, Spinelli J, Cocco P. (2013) Multiple myeloma and occupation: A pooled analysis by the International Multiple Myeloma Consortium. Cancer Epidemiol 37, 300-5.

Pesonen M, Kuuliala O, Henriks-Eckerman M, Aalto-Korte K. (2012) Occupational allergic contact dermatitis caused by eye-lash extension glues. Contact Dermatitis 67(5), 247-320.

Pirodda A, Ferri GG, Mattioli S, Violante FS. (2013) Perilymphatic Fistula: An often Unrecognized Occupational Handicap? A Review of the Literature and Some Consequent Remarks. J Int Adv Otol 9(3), 383-6.

Pralong JA, Seed MJ, Cartier A, Agius RM, Labrecque M. (2012) Is there a place for a computer based asthma hazard prediction model in clinical practice? Occup Environ Med 69(10), 771-2.

Puligheddu M, Conti S, Campagna M, Meloni M, Pau M, Marrosu F, Cocco P. (2012) Cancer risk among shiftworkers: review of the literature . G Ital Med Lav Ergon 3/suppl:624-626 [in Italian]

Rice C, Jin N, Cocco P, Dosemeci M, Buncher CR. (2011) The exposure metric: does including time since exposure in the calculation of working lifetime exposure provide a better understanding of disease risk than the cumulative exposure? Med Lav 102, 343-9

Satta G, Dubois S, Perrotta C, Pilleri M, D’Andrea I, Ennas MG, Lecca M, Nonne T, Zucca M, ‘t Mannetje A, Becker N, de Sanjosé S, Foretova L, Staines A, Maynadié M, Nieters A, Brennan P, Boffetta P, Cocco P. (2011) Risk of multiple myeloma and agricultural exposures. G Ital Med Lav Ergon 33/suppl 3:106-107. [in Italian]

Satta G, D’Andrea I, Ursi M, Nonne T, Avataneo G, Campagna M, Cocco P. (2012) Risk of the most prevalent lymphoma subtypes associate with use of mobile phones. G Ital Med

Lav Ergon 3/suppl:621-623 [in Italian]

Sauni R, Linna A, Oksa P, Nordman H, Tuppurainen M, Uitti J. (2010) Cobalt asthma - a case series from a cobalt plant. Occup Med (London) 60(5), 369-75.

Seed M, Agius RM. (2011) Further corroboration of the asthmagenicity of 5-aminosalicylic acid. Occup Environ Med 68(5) 386.

Stocks SJ, McNamee R, Turner S, Carder M, Agius RM. (2013) Assessing the impact of national level interventions on workplace respiratory disease in the UK: part 1 - changes in workplace exposure legislation and market forces. Occup Environ Med 70(7), 476-82

Stocks SJ, McNamee R, Turner S, Carder M, Agius RM. (2013) Assessing the impact of national level interventions on workplace respiratory disease in the UK: part 2 - regulatory activity by the Health and Safety Executive. Occup Environ Med 70(7), 483-90

Stocks SJ, McNamee R, Turner S, Carder M, Agius RM. (2012) Has EU legislation to reduce exposure to chromate reduced allergic contact dermatitis (UK)? Occup Environ Med 69, 150-152.

Stocks SJ, Turner S, McNamee R, Carder M, Hussey L and Agius RM. (2011) Occupation and work-related ill-health in UK construction workers. Occupational Medicine 61, 407-415

Stocks SJ, Turner S, Carder M, Hussey L, McNamee R, Agius RM. (2010) The incidence of medically reported work-related ill-health in the UK agricultural sector. Occupational Medicine 60(5), 340-7.Stocks SJ, McNamee R, Turner S, Carder M, Agius R. (2010) The incidence of medically reported work-related ill-health in the construction industry. Short report to Occupational and Environmental Medicine 67, 574-576

Suojalehto H, Lindström I, Henriks-Eckerman M, Jungewelter S, Suuronen K. (2011) Occupational Asthma Related to Low Levels of Airborne Methylen Diphenyl Diisocyanate (MDI) in Orthopedic Casting Work. Am. J. Ind. Med 54(12), 906-910.

Suuronen K, Pesonen M, Aalto-Korte K. (2012) Occupational contact allergy to cocamidopropyl betaine and its impurities. Contact Dermatitis 66(5), 286-292.

Suuronen K, Pesonen M, Henriks-Eckerman M, Aalto-Korte K. (2013) Triphenyl phosphite, a new allergen in polyvinylchloride gloves. Contact Dermatitis 68(1), 1-64.

Tooker BC, Newman LS, Bowler RP, Karjalainen A, Oksa P, Vainio H, Pukkala E, Brandt-Rauf PW. (2011) Proteomic detection of cancer in asbestosis patients using SELDI-TOF discovered serum protein biomarkers. Biomarkers 16(2), 181-91.

Turner S, McNamee R, Agius R, Wilkinson SM, Carder M, Stocks SJ. (2012) Evaluating interventions aimed at reducing occupational exposure to latex and rubber glove allergens Occup Environ Med 69, 925-931

Turner S, McNamee R, Roberts C, Bradshaw L, Curran A, Francis M, Fishwick D, Agius RM. (2010) Agreement in diagnosing occupational asthma by occupational and respiratory physicians who report to surveillance schemes for work-related ill-health. Occupational and Environmental Medicine 67, 471-478.

Urban, P., Pelclová, D. (2010). Information about Up-Date of the Czech List of Occupational Diseases (in Czech), Pracovní lékařství 62, 202-203

Vandersmissen GJ, Verhoogen RA, Van Cauwenbergh AF, Godderis L. Determinantsof maximal oxygen uptake (VO2 max) in fire fighter testing. Appl Ergon. 2014Jul;45(4):1063-6. doi: 10.1016/j.apergo.2014.01.001. Epub 2014 Jan 21. PubMedPMID: 24456897.

Van Landuyt, K., Nawrot, T., Geebelen, B., De Munck, J., Snauwaert, J., Yoshihara, K., Scheers, H., Godderis, L., Hoet, P., Van Meerbeek, B. (2011). How much do resin-based dental materials release? A meta-analytical approach. Dental Materials 27(8), 723-747.

Van Landuyt KL, Yoshihara K, Geebelen B, Peumans M, Godderis L, Hoet P, VanMeerbeek B. Should we be concerned about composite (nano-)dust? Dent Mater. 2012 Nov;28(11):1162-70. doi: 10.1016/j.dental.2012.08.011. Epub 2012 Sep 20. PubMedPMID: 22999371.

Van Royen K, Remmen R, Vanmeerbeek M, Godderis L, Mairiaux P, Peremans L. Areview of guidelines for collaboration in substance misuse management. Occup Med (Lond). 2013 Sep;63(6):445-7. doi: 10.1093/occmed/kqt089. Epub 2013 Jul 23.Review. PubMed PMID: 23881120.

Vehmas T, Oksa P, Kivisaari L. (2012) Lung and pleural CT signs predict deaths: 10-year follow-up after lung cancer screening of asbestos-exposed workers. International Archives of Occupational and Environmental Health 85(2), 207-13.

Verhaert N, Moyaert N, Godderis L, Debruyne F, Desloovere C, Luts H. Noiseexposure of care providers during otosurgical procedures. B-ENT. 2013;9(1):3-8.PubMed PMID: 23641584.

Vierikko T, Järvenpää R, Toivio P, Uitti J, Oksa P, Lindholm T, Vehmas T. (2010) Clinical and HRCT screening of heavily asbestos-exposed workers. Int Arch Occup Environ Health. 83(1), 47-54.

Zanardi F, Salvarani R, Cooke RM, Pirastu R, Baccini M, Christiani D, Curti S, Risi A, Barbieri A, Barbieri G, Mattioli S, Violante FS (2013) Carcinoma of the Pharynx and Tonsils in an Occupational Cohort of Asphalt Workers. Epidemiology 24(1), 100-3.

Zanardi F, Cooke RM, Maiorana A, Curti S, Farioli A, Bonfiglioli R, Violante FS, Mattioli S. (2011) Is this case of a very rare disease work-related? A review of reported cases of Pacinian neuroma. Scand J Work Environ Health 37(3), 253-8.

3. Presentations / conference precedings directly relevant to the Modernet agenda AND BASED ON MODERNET collaborations at meetings other than Modernet

Aalto-Korte K. Methylisothiazolinone allergy in patients with occupational allergic contact dermatitis [abstract]. Contact Dermatitis. 2012;66 Suppl 2S1-92. 11th Congress of the European Society of Contact Dermatitis (ESCD), 13–16 June 2012, Malmö, Sweden

Aalto-Korte K. Occupational contact allergy to isocyanates [abstract]. Contact Dermatitis. 2012;66 Suppl 2S92. 11th Congress of the European Society of Contact Dermatitis (ESCD), 13–16 June 2012, Malmö, Sweden

Le Barbier M, Bonneterre V, Ameille J, Telle Lamberton M. Le Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (rnv3p): structure du réseau et organisation de l’émergence clinique. 32e congrès de médecine et santé au travail, Clermont Ferrand 5-8 juin 2012 (related article in Arch. Mal. Prof. Env cited above)

Bonneterre V on behalf of Modernet and RNV3P. New techniques for tracing newly occurring work-related diseases – sentinel and alert systems. Workshop on Occupational Burden of Disease organized by EU-OSHA, Brussels, 10 October 2014

Bonneterre V, Faye S, Le Barbier M on behalf of Modernet WG3. The Occupational Diseases sentinel Clinical Watch System project (OccWatch): a model to be generalised? EU commission’s launched Conference “Occupational Diseases in the EU, The system(s) and their role, “together for disease-free workers”, Brussels, 3rd & 4th December 2013

Bonneterre V, Telle Lamberton M. Surveillance épidémiologique et vigilance en milieu professionnel : place du réseau Européen MODERNET. 32e congrès de médecine et santé au travail, Clermont Ferrand 5-8 juin 2012 (related article in Arch. Mal. Prof. Env cited above)

Bonneterre V, pour le RNV3P. RNV3P : vers une dimension européenne : Modernet. Symposium AFSSET lors du 31e congrès de national de médecine et santé au Travail, Toulouse, 1-4 Juin 2010. Invitation

Bonneterre V. “Collaboration between RNV3P and THOR: An Entente Cordiale”. Lane Symposium, Centre of Occupational and Environmental Health, the Manchester University. Novembre 2012

Bonneterre V, Lagrange E. Amyotrophic Lateral Sclerosis: Looking for environmental risk factors. Centre for Occupational and Environmental Health Seminars. The University of Manchester, 1st Novembre 2012.

Bonneterre V, Pontin F, Bicout DJ, Agius R, de Gaudemaris R, on behalf of rnv3p, THOR, and MODERNET networks. Searching for signals of potentially new disease-exposure associations: Interest of screening work-related diseases surveillance databases with Data Mining approaches? EPICOH 2013, Utrecht. Com. Orale in Mini-symposium « improving the impact of occupational diseases surveillance »

Carder M, Bensefa L, Estikova E, Mattioli S, Noone P, Rivière S, Samant Y, Sludds K, Telle-Lamberton M, Valenty M, Wannag A. EU existing systems recording OD/WRD. EU commission’s launched Conference “Occupational Diseases in the EU, The system(s) and

their role, “together for disease-free workers”, Brussels, 3rd & 4th December 2013

Cocco P. Retrospective assessment of occupational exposures: translational applications to the occupational health practice. ICOH Conference on Education and Training in Occupational Health: Healthy Working Lives for All: Crossing the OH Multidisciplinary Interface. 8th International Conference on Education and Training in Occupational Health, Glasgow 10-12 April, 2008.

Cocco P. Cesare Cappio Borlino, Carlo Manca, Giorgio Marracini. An ICT application for real time surveillance and prompt discovery of emerging new occupational health hazards.

International Congress on Tracing New Occupational Diseases: methodology, recent findings, and implications for OHS policy. Amsterdam, 7-8 April 2011

Curti S, Mattioli S, Baldasseroni A, Zanardi F, Cooke RMT, Farioli A, Violante FS, Coggon D. Distacco di retina e lavoro: incidenza della patologia tra addetti ad attività manuale o non manuale (Toscana, 1997-2005). Convegno Nazionale delle Scuole Italiane di Medicina del Lavoro. Taormina, 10-12 ottobre 2010. Abstracts Book, p. 45.

Curti S, Mattioli S, Baldasseroni A, Cooke RMT, Zanardi F, Farioli A, Violante FS, Coggon D. Incidence rates of surgically treated rhegmatogenous retinal detachment among manual workers, non-manual workers and housewives in Tuscany, Italy. 22nd International Conference on Epidemiology in Occupational Health. EPICOH 2011. Oxford, UK, 7-9 September 2011. Abstracts book, p. 54.

Delaunay M, Godard V, Faye S, Bicout DJ, de Gaudemaris R, Bonneterre V, on behalf of rnv3p. How using Geographical Information Systems (GIS) could allow us to improve Occupational Diseases (OD) surveillance? EPICOH 2013, Utrecht. Com. Orale in Mini-symposium « improving the impact of occupational diseases surveillance »

Dik S, Hoet P, De Smet K, Van Der Straeten C, Scheepers P, Godderis L. (2011). The role of chromium in pseudotumor induction and survival. 41st European Mutagen Annual Meeting. Barcelona, 4-7 Jyly 2011.

Dik A, Tabish A, Scheepers P, Godderis L. (2011). Effects of Environmental Stressors on Histone Modifications: A Systematic Review. Trends in Metals Toxicity and Ecotoxicity. Mechelen, 8 December 2011.

Farioli A, Mattioli S, Zanardi F, Baldasseroni A, Schaafsma F, Cooke RMT, Mancini G, Fierro M, Santangelo C, Fucksia S, Curti S, Violante FS, Verbeek J. Eziologia professionale di una malattia: proposta di stringhe di ricerca per la consultazione di PubMed. Convegno Nazionale delle Scuole Italiane di Medicina del Lavoro. Taormina, 10-12 ottobre 2010. Abstracts Book, p. 29.

Godderis L. (2013). Impact of Environment on the Epigenome. LBMCC seminar. Kirchberg hospital Luxemburg, 29 January 2013.

Godderis L. (2013). Assessing the exposome in occupational cancer. Arbeidshygiëne: van driewieler tot rotator. Woudschoten Zeist, 17-18 April 2013.

Godderis L, De Raedt K, Tabish A, Hoet P. (2012). Gene-environment interaction in the induction of epigenetic alterations in workers. International Congress on Occupational

Health. Cancun, Mexico, 18-23 March 2012.

Godderis L, De Raedt K, Tabish A, Maertens N, Bulterys S, Viaene M, Viaene M. (2012). Do epigenetic changes play a role in the development of chronic toxic encephalopathy?. International Congress on Occupational Health. Cancun, Mexico, 18-23 March 2012.

Godderis L, De Raedt K, Tabish A, Poels K, Maertens N, De Ruyck K, Bulterys S, Thierens H, Viaene M. (2011). Epigenetic alterations induced by solvents. 41st European Mutagen Annual Meeting. Barcelona, 4-7 July 2011.

Godderis L. (2010). Epigenetic Effects in Workers Exposed to Carcinogenic Agents. Epicoh-Medichem Conference. Taipei (Taiwan), 20-25 April 2010.

Godderis L. (2012). The characterization of the exposome and its impact on cancer. Occupational Toxicology - Worker Safety and (Geno)toxicity Considerations. Beerse (Belgium), 23 November 2012.

Godderis L. (2012). How to determine the exposome and its impact on human disease. Biomonitoring of air quality. Antwerpen, 12- 14 November 2012.

Godderis L. (2012). Voorstelling van de visienota voor de toekomst van de arbeidsgeneeskunde in België. 51ste Interprovinciaal Congres Welzijn op het Werk. 51ste Interprovinciaal Congres Welzijn op het Werk. Hotel Stiemerheide Genk, 11 May 2012.

Kuuliala O. Occupational allergic dermatitis from oxidized D-limonene [abstract]. Contact Dermatitis. 2012;66 Suppl 2S48. 11th Congress of the European Society of Contact Dermatitis (ESCD), 13–16 June 2012, Malmö, Sweden

Lenderink A. Occupational physicians’ views on barriers and facilitators in occupational disease reporting in the Netherlands, 30th ICOH Congress Cancun 2012

Lucas Luijckx NB, Van de Brug FJ, Cnossen HJ, Houben GF, Tielemans E. Emerging Risk Identification - The case of food safety and occupational health. Presentation at the 5th iNTeg-Risk congress held in Stuttgart (Germany), 21-22 May 2013.

Mattioli S, Gori D, Di Gregori V, Farioli A, Pia Fantini M, Christiani D, Curti S, Violante F. 0408 PubMed search strings for the study of putative environmental determinants of disease. Occup Environ Med. 2014 Jun;71 Suppl (EPICOH 2014 Chicago Proceedings)

Mattioli S. Diagnostic criteria, Data & Statistics. Occupational Diseases in the EU - The system(s) and their role / Way forward. EU commission’s launched Conference “Occupational Diseases in the EU, The system(s) and their role, “together for disease-free workers”, Brussels, 3rd & 4th December 2013.

Mattioli S, Sauni R, Spreeuwers D, De Schryver A, Valenty M, Rivière S, Curti S. Interventions for reducing the underreporting of occupational diseases –Minisymposium 'Improving the impact of occupational disease surveillance'. 23rd International Conference on Epidemiology in Occupational Health. EPICOH 2013. Utrecht, 18-21 June 2013. Abstracts book, n. 277.

Mattioli S, Delaj L, Gori D, Baldasseroni A, Ricotta L, Curti S, Farioli A, Zanardi F, Violante FS. Evidence-based search strings for the study of farmers’ occupational diseases. 22nd

International Conference on Epidemiology in Occupational Health. EPICOH 2011. Oxford, UK, 7-9 September 2011. Abstracts book, p. 106.

Mattioli S, Gori D, Di Gregori V, Ricotta L, Baldasseroni A, Colosio C, Galletti S, Curti S, Farioli A, Zanardi F, Violante FS. Evidence-based search strings for the study of farmers’ occupational diseases. The IEA-EEF Congress of Epidemiology 2012: Epidemiology for a Fair and Healthy Society. Porto, 5-8 September 2012. Eur J Epidemiol. 2012;27(Suppl 1):S98.

Mattioli S, Baldasseroni A, Curti S, Zanardi F, Cooke R, Farioli A, Violante F, Coggon D. Incidence rates of surgically treated rhegmatogenous retinal detachment in manual workers, non-manual workers and housewives of Tuscany, Italy. International Congress on Tracing New Occupational Diseases. Amsterdam, 7-8 April 2011. Abstracts book, n. 08.

Mattioli S, De Fazio R, Buiatti E, Truffelli D, Zanardi F, Miglietta B, Curti S, Baldasseroni A, Tassinari G, Violante F. Relevance of repeated lifting tasks and high body weight in retinal detachment: results of a case-control study in myopics. International Congress on Tracing New Occupational Diseases. Amsterdam, 7-8 April 2011. Abstracts book, n. 06.

Mattioli S, Zanardi F, Apostoli P, Semeraro F, Curti S, Farioli A, Baldasseroni A, Violante FS. Stringhe di ricerca per lo studio di determinanti professionali di malattia: un esempio di utilizzo pratico [Search strings for study of putative occupational determinants of disease: an example for practice]. 73° Congresso Nazionale SIMLII. Roma, 1-4 dicembre 2010. G Ital Med Lav Erg 2010; 32(Suppl 2):191-2.

Mattioli S, Baldasseroni A, Curti S, Zanardi F, Cooke RMT, Farioli A, Violante FS, Coggon D. Incidence rates of surgically treated rhegmatogenous retinal detachment in manual workers, non-manual workers and housewives of Tuscany, Italy. XXXIV Congresso dell’Associazione Italiana di Epidemiologia. L’epidemiologia e la sanità pubblica nell’Europa che cambia. Firenze, 9 novembre 2010. Abstracts Book, p. 210.

Mattioli S, Zanardi F, Baldasseroni A, Schaafsma F, Cooke RMT, Mancini G, Fierro M, Santangelo C, Farioli A, Fucksia S, Curti S, Violante FS, Verbeek J. Search strings for study of putative occupational determinants of disease. International Congress on Rural Health in Mediterranean and Balkan Countries. Rural Health 2010. Tirana, 22-25 September 2010. Abstracts book, pp. 100-1.

Mehlum IS, Gravseth HM. Registry of outpatients examined by the Norwegian occupational medicine departments. Abstract for ICOHSCOM (International Congress on Tracing New Occupational Diseases) 2011 in Amsterdam, April 2011.

McNamee R. Dec 2013. Trends over time in incidence of selected Occupational Diseases in the EU (2000-2012). EU Commission conference on occupational diseases. December 2013

Mylle G, Godderis L, Verbeke G. (2012). The impact of occupational noise exposure on blood pressure. International Congress on Occupational Health. Cancun, 18-23 March 2012.

Nakládalová M, Ehler E, Pelclová D, Urban P, Hlávková J, Ridzoň P, Fenclová Z, Richter M. Spine Disorders as an Occupational Disease (in Czech). 27th Czech and Slovak Congress of Neurology and Danube Symposium 2013. Praha, 20. – 23. 11 2013. Česk.

Slov. Neurol. 2013, 76/109, Suppl. 2, 44-45

Pal TM. Health surveillance at the production of a new synthetic fiber. The Aramid experience. International workshop Nanolinen. Berlin May 2011 (Relevant to Modernet agenda but not based on Modernet Collaboration)

Pal TM. New work-related risks and then? ( Nieuwe arbeidsrisico’s en dan?). Meeting Contact Group Chemistry ( Contact Groep Chemie). ‘s Hertogenbosch The Netherlands March 2010. (Relevant to Modernet agenda but not based on Modernet Collaboration)

Pelclová D, Zavadilová A, Fenclová Z, Urban P. Update of Czech List of Occupational Diseases, does it reflect the reality? Poster at the 30th International Congress on Occupational Health ICOH, 18-23 March 2012, Cancun, Mexico

Pesonen M. Allergies to protective gloves [abstract]. Contact Dermatitis. 2012;66 Suppl 2S24. 11th Congress of the European Society of Contact Dermatitis (ESCD), 13–16 June 2012, Malmö, SwedenPongprueksa P, Van Landuyt K, Janssens H, De Munck J, Godderis L, Van Meerbeek B. (2013). Effect of photo-initiators on elution and conversion of adhesives. CED-IADR 2013. Florence, Italy, 4-7 September 2013, Abstract No.S0019.

Rivière S, Chevalier A, Penven E, Cadéac-Birman H, Roquelaure Y, Valenty M. Estimation of underreporting of musculoskeletal diseases (MSDs) in France. International Congress on Occupational Health, Mexico 2012

Rivière S, Chevalier A, Penven E, Cadéac-Birman H, Roquelaure Y, Valenty V. Estimation of under-reporting of work-related musculoskeletal diseases (MSDs) in France. 22nd International Conference on Epidemiology in Occupational Health. EPICOH 2011. Oxford, UK, 7-9 September 2011.

Santonen T. Occupational cancer burden – approaches to diagnosis and prevention. EU commission’s launched Conference “Occupational Diseases in the EU, The system(s) and their role, “together for disease-free workers”, Brussels, 3rd & 4th December 2013

Suomela S. Incidence of work-related dermatitis in Finland during 2005-2009 [abstract]. Contact Dermatitis. 2012;66 Suppl 2S24. 11th Congress of the European Society of Contact Dermatitis (ESCD), 13–16 June 2012, Malmö, Sweden

Tabish A, Verwilst J, Hoet P, Godderis L. (2011). Genetic and Epigenetic Effects of Mobile Phone Radiation. Trends in Metals Toxicity and Ecotoxicity. Mechelen, 8 December 2011.

Vandenbroeck S, Moerenhout E, Sercu M, De Man H, De Witte H, Vanbelle E, Godderis L. (2013). Burnout a substantial problem in hospital physicians: a multicenter study on its prevalence, determinants and consequences in 37 Belgian hospitals. Epicoh Conference: "improving the impact". Utrecht, 18-21 June 2013.

Van der Laan G. 22 september 2010. Tirana ICOH SC rural health Conference. Tracing New Occupational Diseases in Agriculture

Van der Laan G. 2 februari 2011. Lucknow, India. Congress Safe Use of Nanomaterials (SUN 2011). Tracing New Occupational Diseases in Nano-workers

Van der Laan G. 7 april 2011, AMC Amsterdam ICOHSCOM Congres. Tracing New Occupational Diseases, an introduction to the theme

Van der Laan G. 19 oktober 2011. Porto, Portugal. International Congress on Biomarkers and Human Exposure to Nanoparticles. Medical surveillance of nanoworkers, an early warning system?Van der Laan G. 19 maart 2012. Cancun, Mexico. International Conference on Occupational Diseases (ICOH) Tracing New Occupational Diseases.

Van der Laan G. 28 august 2012. Ystad, Sweden. Nordic Meeting on OHS in Agriculture. Tracing new occupational diseases in agriculture.

Van der Laan G. 4 september 2013. Brescia, Italy. Summer School Occupational & Environmental Medicine. Tracing new occupational diseases; OHS vigilance.

Van der Laan G. 24 september 2013. Vienna, Austria World Congress of Neurology. Occupational Neurology: from nose to brain (Solvents and Nanomaterials)

Van Landuyt K, Yoshihara K, Geebelen B, De Munck J, Godderis L, Hoet P, Van Meerbeek B. (2011). Contemporary Composites May Release Nano-dust: vol. 521. DIV/CED/2011. Theoretical Building of the Semmelweis University, 03-09-2011.

Van Landuyt K, Yoshihara K, Geebelen B, De Munck J, Peumans M, Godderis L, Hoet P, Van Meerbeek B. (2011). Contemporary composites may release nano-dust. 45th Meeting of the Continental European Division (CED) of IADR, organized together with the Scandinavian Division (NOF). Budapest, Hungary, 31 Aug-3 Sept 2011.

Zavadilová A. Progress in the search after new occupational diseases in the Czech Republic (in Czech). Seminar at the Dept. for Occupational Medicine, 1st Medical School, Charles University, Prague 22. 3. 2013

Zavadilová A. Detection of New Occupational Diseases in European Countries (in Czech). Seminar at the Dept. for Occupational Medicine, 1st Medical School, Charles University, Prague, 22. 6. 2012

4. Presentations / conference precedings directly relevant to the Modernet agenda AND BASED ON MODERNET collaborations at Modernet meetings

Adams E. Non-specific Interstitial Pneumonia: A case report of a flooring worker exposed to isocyanate fumes. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Agius R. Occupational diseases-old and new. How can they be traced? Conference MALPROF system and networks for the monitoring of occupational diseases. Cost-Auditorium INAIL. Rome, 9 Novembre 2012.

Agius RM, Carder M, Hussey L, Stocks SJ, Money A, Turner S, McNamee R. Triangulated and targeted data collection. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Agius RM, Hussey L, Thorley K, Zarin N. Using health surveillance data for online peer-benchmarking as an educational tool to motivate participation in reporting. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bakker JG. COST : Action StanDerm (TD 1206) and Modernet. Results meeting Berlin COST-MODERNET Conference, Paris, 16-18 October 2013.

Carder M, McNamee R, Hussey L, Agius RM. Best national estimates of trends in incidence of occupational and work related disease through multiple reporting schemes. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Le Barbier M. A new national thesaurus on occupational exposures. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Le Barbier M, Christophe Paris and the rnv3p members. French National Network for Vigilance and Prevention of Occupational Diseases- New Information system. COST-MODERNET Conference, Paris, 16-18 October 2013.

Bensefa L. Allergic occupational dermatitis in France: major allergens and temporal trends for period 2001-2009 in the RNV3P (first session). COST-MODERNET Conference, Leuven, 12-14 June 2012.

Bensefa L. A new cause of occupational asthma induced by Chrysonilia sitophila in workers exposed to coffee grounds. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Bonneterre V, Bicout DJ, De Gaudemaris R. Application of pharmacovigilance methods in OHS. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Ameille J, Telle Lamberton M. Tracing newly occurring occupational diseases with a sentinel clinical approach: from detection to alert. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V. Searching for new occupational diseases with a dual approach: clinical watch system and data mining analyses conducted on suitable databases. Conference MALPROF system and networks for the monitoring of occupational diseases. Auditorium INAIL. Rome, 9 Novembre 2012.

Bonneterre V, Ameille J, Telle Lamberton M. Tracing newly occurring occupational diseases with a sentinel clinical approach: from detection to alert. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Lacroix M, Focant JF. 3 cases of Non Hodgkin Lymphoma among welders exposed more than 10 years to a spray containing methylene chloride (dichloromethane). COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Charles J, Salameire D, Bourrain JL, Templier I, Beani JC, Leccia MT. Case-report: precancerous and cancerous skin lesions limited to area in contact with epoxy resin in a man applying epoxy resin on floors. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Pradat PF, Buisson C, Lagrange E, Bicout D, Boumediene F, Catinon M, Corona C, Elbaz A, Garnier R and the French collaborative network for ALS clusters detection and investigation. Occupational and Environmental clusters of Amyotrophic Lateral Sclerosis (ALS) with exposure to metals polishing dusts. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Bon F, Bru JP, Bland S. A case of pulmonary infection to Mycobacterium fortuitum in a house painter involved in water-damaged buildings remediation. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Persoons R, Hamm B, de Gaudemaris R. Extrinsic Allergic Alveolitis in a manicurist with ethyl methacrylate: first case report. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Bonneterre V, Gallot C, Bicout DJ, de Gaudemaris R, on behalf of the RNV3P. Could Geographic Information Systems (GIS) be of interest for analysing the data of our occupational diseases surveillance scheme (ODSS)? Example with RNV3P. Part I : Numerator and Denominator assessment. COST-MODERNET Conference, Manchester, 22-24 November 2011

Brandi G, Di Girolamo S, Farioli A, de Rosa F, Curti S, Pinna AD, Ercolani G, Violante FS, Biasco G, Mattioli S. Findings from an explorative case-control analysis on the association between occupational exposure to asbestos and cholangiocarcinoma risk. COST-MODERNET Conference, Manchester, 22-24 November 2011

Carder M. Voluntary medical reporting of work-related illness in the Republic of Ireland: the challenges of reporting and UK data comparisons. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Carder M, Bensefa L, Estikova E, Mattioli S, Noone P, Rivière S, Samant Y, Sludds K, Telle-Lamberton M, Valenty M, Wannag A. EU existing systems recording OD/WRD. COST-MODERNET Conference, Paris, 16-18 October 2013.

Cocco P. Lymphoma as an occupational diseases. COST-MODERNET Conference, Bucharest 29–31 May 2013

Cocco P, Silke Kleefeld. Advances in the retrospective assessment of occupational exposures: results from the multicentre European case-control study Epilymph. COST-MODERNET Conference, Manchester, 22-24 November 2011

Cocco P. Role of occupational exposures in the etiology of non-Hodgkin lymphoma: recent findings from the Epilymph and Interlymph studies. COST-MODERNET Meeting, Bucharest, 29-31 May 2013Colosio C. Exposure and risk profiles for retrospective pesticide exposure assessment in epidemiological studies. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Colosio C. Special issue Occupational Medicine (London). COST-MODERNET Conference, Paris, 16-18 October 2013.

Costa David J. EU Commission and OD/WRD; issues and progress of December conference on OD. COST-MODERNET Conference, Paris, 16-18 October 2013.

Cnossen HJ, Van de Brug FJ, Voogd E, Spaan S, Tielemans E. Early signals for emerging risks in occupational safety and health. COST-MODERNET Conference, Paris, 16-18 October 2013..

De Schryver A, Van Winckel M, Van Hooste W, Wullepit G, Cornelis K, Charlier A,

Colemonts K. Helicobacter pylori in healthcare workers: a new occupational infection? COST-MODERNET Conference, Manchester, 22-24 November 2011.

De Schryver A. Reporting and registration of occupational diseases in Belgium – an overview. COST-MODERNET Conference, Leuven, 12-14 June 2012.

De Vocht F, Kromhout H, Van Tongeren M, Cherrie J, Tielemans E, Agius R. Role of occupational hygiene/exposure assessment. COST-MODERNET Conference, Paris, 16-18 October 2013..

Faye S. Applying count data models to visualize temporal trends in the rnv3p network. COST-MODERNET Conference, Bucharest 29–31 May 2013

Faye S, Le Barbier M, Delaunay M, Telle-Lamberton M. Paris area’s Occupational Disease centres and the RNV3P members. COST-MODERNET Conference, Paris, 16-18 October 2013.

Faye S. Indicators of data quality for health databases: the example of the rnv3p network. COST-MODERNET Conference, Bucharest 29–31 May 2013

Forman SD, Turner S, McNamee R, Carder M, Agius R. Investigating the attribution of work to Skin Cancer case reporting to The Health and Occupation research (THOR) network. COST-MODERNET Conference, Manchester, 22-24 November 2011.

Gallagher F, Carder M, Money A, Hussey L, Turner S, McNamee R, Agius R. Development of guidance for reporting cases to work related ill health surveillance schemes. COST-MODERNET Conference, Manchester, 22-24 November 2011.

Godderis L, Schouteden M, Mylle G, Vandenbroek S. Precube: data warehouse for detection and evaluation of trends of occupational diseases. COST-MODERNET Conference, Bucharest 29–31 May 2013.

Godderis L, Mylle G, Vandenbroek S. Precube: a data warehouse for the detection and evaluation of trends of occupational diseases. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Godderis L, Vandenbroek S, Faisandier L, Bonneterre V. (2011). Detection of emerging diseases in occupational health. COST-MODERNET Conference, Manchester, 22-24 November 2011.

Hussey L, Turner S, McNamee R, Agius R. Work-related ill-health reporting from General Practice-illuminating the blind spot. COST-MODERNET Conference, Manchester, 22-24 November 2011.

Hussey L, Turner S, McNamee R, Agius R. Calculating incidence rates of work-related ill-health from General Practice – establishing the THOR-GP denominator. COST-MODERNET Conference, Manchester, 22-24 November 2011.

Hussey L. Using multiple data sources to triangulate work-related ill-health incidence estimates. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Lenderink A, Braam I, Moeijes F, Van der Molen H, Smits P, Kuijer P, Bakker J, Sorgdrager B, Spreeuwers D. Occupational physicians’ views on barriers and facilitators in

occupational disease reporting in the Netherlands. COST-MODERNET Conference, Manchester, 22-24 November 2011.Lenderink A. Review on the validity of self-report to measure work-related illness. COST-MODERNET Conference, Amsterdam, 7-8 April 2011

Lenderink A. SIGNAAL: COST-MODERNET Conference, Bucharest 29–31 May 2013Luzati A. Presenting the national asbestos-related policy in Albania. COST-MODERNET Conference, Bucharest 29–31 May 2013

Mattioli S. Could Occupational Exposure to n-Hexane and Other Solvents Precipitate Visual Failure in Leber Hereditary Optic Neuropathy. COST-MODERNET Conference, Leuven, 12-14 June 2012.

McNamee R, Chen Y, Hussey L, Agius R. Reporting frequency and behaviour in voluntary surveillance schemes. COST-MODERNET Conference, Manchester, 22-24 November 2011.

McNamee R. Influence of ‘zero case’ reports when estimating incidence and trends in work-related (WR) disease. An investigation in the GB EPIDERM scheme 1996-2010. COST-MODERNET Conference, Leuven, 12-14 June 2012.

McNamee R. Using surveillance data to describe national trends and evaluate interventions. Conference MALPROF system and networks for the monitoring of occupational diseases. Auditorium INAIL. Rome, 9 Novembre 2012.

McNamee R. New issues emerging from WG2 work Cost Modernet Conference, Paris, France, 16-18 October 2013.

McNamee R. Design of studies to evaluate effect of national interventions to reduce work-related diseases. COST-MODERNET Conference, Zaragoza 9-11 April 2014.

McNamee R. Influence of ‘zero cases’ reports when estimating time trends in Work-related Disease: new results. COST-MODERNET Conference, Zaragoza 9-11 April 2014.

Miller P. Role of Health Economics. COST-MODERNET Conference, Paris, 16-18 October 2013.Mylle G. The impact of occupational noise exposure on blood pressure. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Nerrière-Catelinois. Use of adjusted ROR as association indicators between diseases and activity sectors on rnv3p data from OD centres and occupational health services. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Palmen N. Emerging Risk Identification Support service (ERIS) that identifies new and unexpected hazards and helps stakeholders make well-considered decisions at an early stage. COST-MODERNET Conference, Bucharest 29–31 May 2013

Papale/Campo. Cervical hernia: occupational disease? COST-MODERNET Conference, Bucharest 29–31 May 2013

Pelclová D, Nakládalová M, Urban P, Ridzoň P, Hlávková J, Fenclová Z, Ehler E, Richter M, Zavadilová A. Development of an objective method for quantification of the

http://www.tno.nl/content.cfm?context=thema&content=prop_case&laag1=891&laag2=903&laag3=73&item_id=1330&Taal=2

etiologic fraction of the occupational risk factors in the chronic lumbar vertebral column diseases – Presentation of a Project IGA. Paříž: COST-MODERNET Conference, Paris, 16-18 October 2013.

Pilorget C. Classifications of occupations and economic activities used in MODERNET. COST-MODERNET Conference, Paris, 16-18 October 2013.

Pranjić N, Dedić S. Occupational lung cancer risk in Tuzla Canton, Bosnia and Herzegovina. COST-MODERNET Conference, Manchester, 22-24 November 2011

Pranjic N. Presenteeism and consequences of presenteeism to health and work performances among primary health care workers with indirect costs following Levi exact assessment. COST-MODERNET Conference, Bucharest 29–31 May 2013

Rempel D. A presentation on Upper Limb disorders. COST-MODERNET Conference, Bucharest 29–31 May 2013

Rieutort D. Observational Surveillance of Occupational Health Problems. COST-MODERNET Conference, Bucharest 29–31 May 2013

Rivière S, Chevalier A, Penven E, Cadeac-Birman H, Roquelaure Y, Valenty M. Under-reporting of work-related musculoskeletal diseases (MSDs) in France. COST-MODERNET Conference, Manchester, 22-24 November 2011Seed M, Agius RM. Iteration and evaluation of Quantitative Structure Activity Relationships to identify novel occupational allergens. International Congress on Tracing New Occupational Diseases: methodology, recent findings and implications for OHS policy. Amsterdam, 7,8 April 2011.

Seed M, Agius R. Using Quantitative Structure Activity Relationships to help corroborate sentinel case reports of occupational respiratory disease. COST-MODERNET Conference, Manchester, 22-24 November 2011Schneider E. EU-OSHA perspective on recognising new hazards and risks and work-related diseases Cost. COST-MODERNET Conference, Paris, 16-18 October 2013.

Spreeuwers D. The current situation of occupational diseases systems in Europe, in particular relative to Commission Recommendation 2003/670/EC COST-MODERNET meeting. COST-MODERNET Conference, Manchester, 22-24 November 2011

Stocks SJ, Turner S, McNamee R, Carder M, Agius R. Evaluating interventions to reduce allergic contact dermatitis due to occupational latex and chromate exposure. COST-MODERNET Conference, Amsterdam, 7-8 April 2011.

Stocks SJ, Carder M, Agius R. Evaluating the impact of health and safety interventions and market forces on the incidence of work-related asthma. COST-MODERNET Conference, Manchester, 22-24 November 2011

Stocks SJ, Carder M, Agius R. Using standardised incidence rate ratios to identify occupations and industries at increased risk of medically-reported work-related ill-health. COST-MODERNET meeting. COST-MODERNET Conference, Manchester, 22-24 November 2011

Stocks SJ. Changes in the incidence of short latency work-related respiratory disease

concurrent with changes in legislation for workplace exposure limits. COST-MODERNET Conference, Leuven, 12-14 June 2012.

Stocks SJ. Results of survey: trends in allergic contact dermatitis and the chromate directive. COST-MODERNET Conference, Bucharest 29–31 May 2013

Stocks SJ and McNamee R. Trends in incidence of some WRD across EU participating countries. COST-MODERNET Conference, Paris, 16-18 October 2013.

Stocks SJ and WG2 collaborators. A comparison of trends in incidence of occupational diseases across 10 European Countries (2000-2012). COST-MODERNET Conference, Zaragoza, 9-11 April 2014

Telle-Lamberton M, Paris C, Bensefa-Colas L, Faye S, Larabi L, Le Barbier M, Lasfargues G, Luc A, Ngatchou-Wandji J, and the RNV3P members. Trends in work related diseases in France between 2001 and 2009: examples of contributions from the French National Network for Vigilance and Prevention of Occupational Diseases. COST-MODERNET Conference, Manchester, 22-24 November 2011

Urban P, Fenclová Z, Bittner Z, Zavadilová A. Occupational Diseases in the Czech Republic in 2012. COST-MODERNET Conference, Bucharest 29–31 May 2013

Urban P, Fenclová Z, Zavadilová A, Pelclová D. Occupational Diseases in the Czech Republic in 2011. COST-MODERNET Conference, Leuven, 12-14 June 2012

Urban P, Bittner Z. How Can Czech Republic Contribute to the MODERNET? COST-MODERNET Conference, Amsterdam, 7-8 April 2011

Urban P, Zavadilová A, Pelclová D. Latest Developments Concerning the Czech List of Occupational Diseases. COST-MODERNET Conference, Manchester, 22-24 November 2011

Valenty M, Boutou-Kempf O, Jarchand J, Imbernon E. The French national epidemiological surveillance system of nanoworkers. COST-MODERNET Conference, Manchester, 22-24 November 2011

Van der Laan G. Reconstructing the EU Recommendation on Occupational Diseases? COST-MODERNET Conference, Leuven. 12-14 June 2012.

Van der Laan G, Pal T, Van Broekhuijzen P. An early warning system for workers with Nanomaterials? COST-MODERNET Conference, Manchester, 22-24 November 2011

Van der Laan G. A case of Leu-enkephalin intoxication? COST-MODERNET meeting. COST-MODERNET Conference, Manchester, 22-24 November 2011

Van der Laan G. Progress report. COST-MODERNET Conference, Bucharest 29–31 May 2013

Van der Molen H. Interrupted time series for evaluation of preventive interventions? - experiences from a review on injuries in construction work. COST-MODERNET Conference, Bucharest 29–31 May 2013

Van der Molen H. Facilitators for prevention of occupational diseases -A qualitative study. COST-MODERNET Conference, Bucharest 29–31 May 2013

Wannag A. Coding systems. Changing the general practitioners ICPC disease codes to the ICD-10 system. Easier use of exposure codes. COST-MODERNET Conference, Manchester, 22-24 November 2011.

Zavadilová A: NEEDS and BARRIERS in tracing new occupational diseases and data collection in the Czech Republic. COST-MODERNET Conference, Leuven, 12-14 June 2012

Documents

COST - MODERNET | Monitoring Occupational … Report... · Web viewOur argument, presented at the EU conference in Brussels in December 2013 and reinforced in our publications, is