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Cristian Gheorghe, MD, PhD, FASGE
Personal Information:
Date of birth: 31 august 1959
Birthplace: Bucharest
Citizenship: Romanian
Adress
(hospital):
Center for Digestive Diseases and Liver Transplantation
Fundeni Clinical Institute
Sos Fundeni nr. 258
72437 Bucharest, Romania
Phone: +40212750500;
Fax : +40213180455(secretary)
e-mail: [email protected]
Adress
Str. Sf. Niceta nr. 18, sector 2, Bucharest, România
Current Position:
Professor of Gastroenterology, University of Medicine and Pharmacy "Carol Davila" Bucharest,
Romania;
Chief of the 1st Gastroenterology Department of Center for Digestive Disease and Liver
Transplantation
Coordinator of Diagnostic and Therapeutic Digestive Endoscopy Laboratory, Fundeni Clinical
Institute, Bucharest, Romania
Education:
Graduated medicine at the “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
in 1984, then specialized in internal medicine and gastroenterology
1994 : Assistant Professor
1997: Senior physician in gastroenterology.
1996: PhD degree with the PhD Thesis: “Portal .hypertensive gastropathy”
2005: Associate Professor
2011: Full Profesor of Gastroenterology at the ”Carol Davila“ University of Medicine and Pharmacy,
Bucharest
2013: Habilitation Thesis: ”Perspectives in diagnosis and therapeutic digestive endoscopy”
2017:Fellow of the American Society for Gastrointestinal Endoscopy (FASGE)
Training abroad:
Diagnostic& Therapeutic Digestive Endoscopy
- Academic Medical Center Amsterdam, Netherlands (Prof. Kees Huibregtse, Prof. Paul
Fockens) 1993, 1997-1998, 2005
- Mainz, Germany (Prof. Ralf Kiesslich) 2007
- MUSC Charleston, South Carolina, SUA (Prof Robert Hawes) 2008
Administrative positions:
1999-present Member of the American Society for Gastrointestinal Endoscopy (ASGE)
1999-present Member of the American Society for Gastrointestinal Endoscopy (ASGE)
2004-2005 Vice-president of the Gastroenterology Comission of Romanian College of
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Physicians
2001-2009 Secretary General of the Romanian Society of Digestive Endoscopy
(SRED)
2002-2010 Member of the International Committee of American College of
Gastroenterology (ACG)
2006 – 2010 Councillor of the Board of the European Society for Gastrointestinal
Endoscopy (ESGE) , 2006-2010
2009-2011 President elect of the Romanian Society for Digestive Endoscopy (SRED)
2009- 2012 ESGE delegate in European Union of Medical Specialties in (UEMS) /
United European Gastroenterology Federation (UEGF) for Continuous
Medical Education (CME)
July 2010-currently
2012-2014
President of the Gastroenterology Expert Comission of Romanian College
of Physician
President of the Assocation of Romanian Pancreatic Pathology (APPR)
October 2014 – June
2015
2017-2019
President of the Gastroenterology Comission of Romanian Ministry of
Health
Future President elect of Romanian Society of Gastrointestinal Endoscopy
Prizes, Decorations, National & International Recognition :
2010 ; The “Sanitary Order Merit as rank of Knight”
2012 :The “TopMedici 2012” Prize for outstanding contribution to the Romanian medicine
Main research interests:
Therapeutic endoscopy
Early diagnosis and prophylaxis of gastrointestinal cancers and pancreatic cancers
New endoscopic techniques
Portal hypertension
Inflammatory bowel disease
Editorial position:
Co-editor: Archives of the Balkan Medical Union (1997-present)
Member of the Editorial Board: Journal of Gastrointestinal and Liver Diseases (1998-present)
Expert review in gastroenterology (2001-present)
Hepatogastroenterology (2001-2011)
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Membership of Scientific Societies:
Member of the Romanian Society of Gastroenterology & Hepatology (SRGH)
Member of the Romanian Society of Digestive Endoscopy (SRED)
Member of the European Association for the Study of the Liver (EASL)
Member of the Balkan Medical Union (BMU)
Member of the American Society for Gastrointestinal Endoscopy (ASGE)
Member of the European Society of Gastrointestinal Endoscopy (ESGE)
Member of the Romanian Society of Parenteral and Enteral Nutrition (ROSPEN)
Member of the European Society for Parenteral and Enteral Nutrition (ESPEN)
Member of the American College of Gastroenterology (ACG)
Member of the Romanian Society of Endoscopic Surgery and Other Interventional Techniques
(ARCE)
Member of the European Association for Endoscopic Surgery (EAES)
Member of the American Gastroenterological Association (AGA)
Member of the European Pancreatic Club (European Pancreatic Club)
Member of Romanian Club of Crohn and Colitis (RCCC)
Member of the European Society of Crohn and Colitis (European Crohn's and colitis Organization)
(ECCO)
Founding member of the Romanian Society of Colo-Proctology
Contributions to education in endoscopy on the international and national level:
Coordinator of the National Program of Digestive Diagnosis Endoscopy in Romania: 2002-
2005
Coordinator of the National Program of Digestive Therapeutic Endoscopy in Romania: 2005 -
present
Course director for Digestive Endoscopy of the 17th World Congress of the International
Association of Surgeons and Gastroenterologists ( IASGO), Bucharest, Romania, September 5-8,
2007
ESGE Director for ESGE Live Endoscopy Workshop Cluj-Napoca Romania,15-16 October
2009
Director of pre-Congress Digestive Endoscopy course (UptoDate in GI Therapeutic
Endoscopy in 2013) of the 23rd World Congress of IASGO, Bucharest, Romania, 18-21 September
2013
Director of Digestive pre-Congress Endoscopy course (Clinical impact of new endoscopic
techniques in gastroenterology) of the 35th Romanian Congress of Gastroenterology,Hepatology and
Digestive Endoscopy Iasi, Romania, June 11-13 2015
Director of Pancreatic Disease Course of Annual Course for Pancreatic Diseases 2013-2014
Scientific Coordinator of Bucharest PancreaticFest Bucharest, Romania, September 2015,
2016
Coordinator for the 1st National Course for PEG Training for Parkinson disease in
multidisciplinary team Bucharest Romania 7-10 November 2016
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Significant scientific contribution contribution to the field of endoscopy:
First endoscopic mucosal resection in Romania for early gastric cancer (published in 2002)
First argon plama coagulation case series for radiation proctitis in Romania (published
in 2003)
First case series of primary prophylaxis of variceal bleeding in cirrhotics awaiting
liver transplantation. (published in 2002, 2006)
First systematic use of EUS and EUS-FNA with my team for staging esophageal
cancer and pancreatic masses in Romania (published in 2004, 2006, 2011)
First electroincision of anastomotic stricture after curative resection for gastric cancer
in Romania (2009)
First use of NBI endoscopy for diagnosis of malignant and premalignant
gastrointestinal lesions in Romania (published in 2006)
First use of confocal endomicroscopy for in vivo microscopic analysis of upper
gastrointestinal tract premalignant and malignant lesions and for assessing mucosal healing
in patients with ulcerative colitis (published in 2008, 2011)
Scientific and professional activity:
Original articles published in ISI indexed journals: 100
Publications presented as posters or oral presentations with abstracts published in ISBN
indexed volumes: more than 400
Books and book chapters: 50
Participation as director in national research programs: 8
Participation as researcher in national research programs:10
Participation in clinical national and international studies: 20
h-index Google Scholar: 21
ORIGINAL PAPERS PUBLISHED IN INDEXED INTERNATIONAL JOURNALS
1. L. Gheorghe, I. Popescu, C. Gheorghe, G. Aposteanu, C. Popescu, Al. Oproiu. Fatal
intestinal hemorrhage complicating ileal lymphoma after Cyclosporine for unresponsive
celiac disease. Hepato-Gastroenterology 1997; 44: 1342-1345
2. M. Manuc, C. Oproiu, M. Ionescu, D. Popovici, R. Dutu, C. Popescu, C. Gheorghe, Al.
Oproiu. Esophageal tumor with an unusual histological appearance: Hepato-
Gastroenterology 1998; 45: 109-113
3. C. Gheorghe, G. Aposteanu, C. Popescu, L. Gheorghe, A. Oproiu, I. Popescu. Long
esophageal stricture in Crohn’s disease. Hepato-Gastroenterology 1998; 45: 738-741
4. Ionescu M, Tomulescu V, Gheorghe C, Popescu I. Post-caustic esophageal stenosis.
Chirurgia 2000; 95 (1): 23-28
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5. G. Becheanu, R. Stoia, C. Gheorghe, B. Stamm. Disseminated infection of the digestive
tract caused by cytomegalic virus in a patient with Hodgkin’s disease. J Cellular and
Molecular Medicine 2001; 5: 436-437
6. I. Popescu, D. Tulbure, M. Ionescu, R. Vasile, S. Baila, S. Ciurea, D. Hrehoret, V.
Brasoveanu, D. Pietrareanu, P. Boeti, L. Dumitru, G. Droc, D. Enescu, C. Gheorghe, M.
Boros, V. Herlea, M. Mihaila. Liver transplantation - considerations over 8 cases operated in
the year 2000; Chirurgia 2001; 96 (5): 453-467
7. C. Gheorghe, I. Sporea, G. Becheanu, L. Gheorghe. Endoscopic mucosal resection for
early gastric cancer. Romanian J Gastroenterology 2002; 11: 33-38
8. L. Gheorghe, I. Bancilă, C. Gheorghe, V. Herlea, C. Vasilescu, G. Aposteanu. Antro-
duodenal tuberculosis causing gastric outlet obstruction – a rare presentation of a protean
disease. Romanian J Gastroenterology 2002; 11: 149-152
9. C. Gheorghe, L. Gheorghe, A. Mihalcea, S. Georgescu. TIPS pentru HDS variceale severe
la un pacient cu ciroză hepatică Romanian J Gastroenterology 2002; 11: 65-67
10. C. Preda, L. Gheorghe, C. Gheorghe, M. Diculescu, A. Mihalcea, S. Georgescu, I.
Popescu. Pancreatită cronică complicată cu tromboză de venă portă, hipertensiune portală
segmentară şi HDS prin ruptură de varice de fornix gastric Romanian J Gastroenterology
2002; 11: 159-161
11. L. Gheorghe, C. Gheorghe, A. Mihalcea, M. Grasu, S. Georgescu. Chemoembolization
for hepatocellular carcinoma Romanian J Gastroenterology 2002; 11: 255-257
12. L. Gheorghe, A. Croitoru, A. Stoicescu, C. Gheorghe, G. Becheanu. Kruckenberg tumor
secondary to colorectal carcinoma Romanian J Gastroenterology 2002; 11: 255-257
13. L. Gheorghe, C. Gheorghe, M. Badea, R. Vadan, I. Parvulescu, C. Toader, L. Tugui, O.
Papuc, R. Ionescu, C. Preda, I. Calin, M. Diculescu. Infliximab for Crohn’s disease in
clinical practice: the experience of a single center in Romania. Romanian J Gastroenterology
2003; 12: 7-13
14. C. Gheorghe, L. Gheorghe, R. Iacob, S. Iacob, I. Simionov, I. Bancilă. Argon plama
coagulation for radiation proctitis. Romanian J Gastroenterology 2003; 12: 107-112
15. R. Vadan, L. Gheorghe, G. Becheanu, R. Iacob, S. Iacob, C. Gheorghe. Predictive
factors for the severity of liver fibrosis in patients with chronic hepatitis C and moderate
alcohol consumption. Romanian J Gastroenterology 2003; 12: 183-188
16. I. Popescu, M. Ionescu, S. Ciurea, C. Stănescu, C. Gheorghe, R. Anghel, A. Croitoru.
Neoadjuvant radiochemotherapy for the treatment of epidermoid oesophageal carcinoma:
preliminary results on 15 patients. Chirurgia 2003; 98 (6): 499-508
17. L. Gheorghe, C. Gheorghe, G. Becheanu. Non-alcoholic steato-hepatitis (NASH)
Romanian J Gastroenterology 2003; 12: 65-67
18. L. Gheorghe, R. Vadan, V. Herlea, C. Gheorghe, I. Popescu. Chronic recurrent hepatitis
C after liver transplantations Romanian J Gastroenterology 2003; 12: 156-158
19. A. Ionescu, L. Gheorghe, C. Gheorghe, S. Iacob. Budd-Chiari syndrome Romanian J
Gastroententerology 2003; 12: 247-249
20. M. Jinga, C. Gheorghe, M. Dumitrescu, L. Gheorghe, T. Nicolaie. Endoscopic
ultrasound guided fine needle aspiration biopsy in the diagnosis of pancreatic masses.
Romanian J Gastroenterology 2004; 13: 49-54
21. L. Gheorghe, S. Iacob, C. Gheorghe, R. Iacob, I. Simionov, R. Vadan, G. Becheanu, I.
Parvulescu, C. Toader. Frequency and predictive factors for overlap syndrome between
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autoimmune hepatitis and cholestatic liver disease. European J Gastroenterology Hepatolgy
2004; 16: 585-592
22. C. Gheorghe, I. Bancila, R. Stoia, L. Gheorghe, G. Becheanu, C. Dobre, R. Brescan.
Regression of gastric MALT-lymphoma under specific therapy may be predicted by
endoscopic ultrasound. Romanian J Gastroenterology 2004; 13: 129-134
23. L. Gheorghe, I. Popescu, S. Iacob, C. Gheorghe, R. Vadan, A. Constantinescu, R. Iacob,
G. Becheanu, C. Angelescu, M. Diculescu. Wilson’s disease: a challenge of diagnosis. The
5-years experience of a tertiary centre. Romanian J Gastroenterology 2004; 13: 179-185
24. C. Gheorghe, O. Pascu, L. Gheorghe, R. Iacob, E. Dumitru, M. Tantau, R, Vadan, A.
Goldis, G. Balan, S. Iacob, D. Dobru, A. Saftoiu. Epidemiology of inflammatory bowel
disease in adults who refer to gastroenterology care in Romania: a multicentric study.
European J Gastroenterology Hepatology 2004; 16: 1153-1161
25. Balan C, Balut C, Gheorghe L, Gheorghe C, Gheorghiu E, Ursu G. Experimental
determination of blood permittivity and conductivity in simple shear flow. Clinical
Hemorheology Microcirculation 2004; 30 (3-4): 359-364
26. D. Dobru, O. Pascu, M. Tantau, C. Gheorghe, A. Goldis, G. Balan, F. Coman, A.
Fraticiu, E. Dumitru, E. Miutescu, A. Saftoiu, V. Bacarea. An epidemiological study of
gastric cancer in the adult population referred to gastroenterology medical services in
Romania – a multicentric study. Romanian J Gastroenterology 2004; 13:275-280
27. D. Cacovean, C. Gheorghe, D. David, O. Stanciulea, V. Herlea, C. Vasilescu. Hemoragia
digestiva superioara de cauza rara: schwanom benign duodenal. Chirurgia 2004; 99: 571-578
28. R. Vadan, L. Gheorghe, C. Gheorghe, M. Ghinea, S. Georgescu. Chronic pancreatitis
requiring nutritional support. Romanian J Gastroenterology 2004; 13: 64-65
29. M. Badea, L. Gheorghe, G. Becheanu, C. Gheorghe, I. Lupescu, S. Georgescu, C.
Stanescu, L. Popescu. Carcinoid syndrome. Bronchic carcinoid with extensive metastasis
involving the liver, lymph nodes, and bones successfully treated with lanreotid . Romanian J
Gastroenterology 2004; 13: 147-149
30. C. Gheorghe, L.Gheorghe, G. Becheanu, R. Iacob, S. Iacob. Peptic esophagitis.
Romanian J Gastroenterology2004; 13: 349-350
31. Popescu I, Ionescu M, Tulbure D, Ciurea S, Baila S, Brasoveanu V, Hrehoret D, Sarbu-
Boeti P, Pietrareanu D, Alexandrescu S, Dorobantu B, Gheorghe L, Gheorghe C, Mihaila M,
Boros M, Croitoru M, Herlea V. Transplantul hepatic ortotopic de la donator cadavru la
adult. Experienta Centrului de Chirurgie Generala si Transplant Hepatic Fundeni. Chirurgia
2005; 100: 13-26
32. L. Gheorghe, I. Popescu, R. Iacob, S. Iacob, C. Gheorghe. Predictors of death on the
waiting list for liver transplantation characterized by a long waiting time. Transplant
International 2005; 18: 572-576
33. C. Gheorghe. Endoscopic clipping focused on “triclip”for bleeding Dieulafoy’s lesion in
the colon. Romanian J Gastroenterology 2005; 14: 79-82
34. L. Gheorghe, S. Iacob, C. Gheorghe. Liver biopsy under ultrasound control for diffuse
liver disease – toward a faster, safer, cost-effective and easy acceptable procedure. Romanian
J Gastroenterology 2005; 14: 97-98
35. L. Gheorghe, M. Grigorescu, S. Iacob, D. Damian, C. Gheorghe, R. Iacob, I. Simionov,
R. Vadan, I. Parvulescu, I. Bancila. Effectiveness and tolerability of pegylated interferon -
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2A and ribavirin combination therapy in Romanian patients with chronic hepatitis C: from
clinical trials to clinical practice. Romanian J Gastroenterology 2005; 14: 109-115
36. L. Gheorghe, R. Iacob, R. Vadan, S. Iacob, C. Gheorghe. Improvement of hepatic
encephalopathy using a modified high-calorie high-protein diet. Romanian J
Gastroenterology 2005; 14: 231-238
37. L. Gheorghe, S. Iacob, I Simionov, R Vadan, C Gheorghe, R Iacob, I Parvulescu, I
Constantinescu. Natural history of compensated hepatitis B and D viruses cirrhosis.
Romanian J Gastroenterology 2005; 14: 329-336
38. R Iacob, S Iacob, L Gheorghe, C Gheorghe, M Diculescu. The use of IT in the medical
system has economic and research advantages – the experience of Fundeni Gastroenterology
and Hepatology Center. Romanian J Gastroenterology 2005; 14: 426-429
39. L.Gheorghe, S. Iacob, C. Gheorghe, G. Becheanu. Antiviral therapy for AgHBe-negative
chronic hepatitis . Romanian J Gastroenterology 2005; 13: 90-91
32. R. Vadan, G. Becheanu, C. Gheorghe. Colita pseudomembranoasa. Romanian J
Gastroenterology 2005; 14: 190-191
33. L Gheorghe, S Iacob, C Gheorghe. Profilaxia infectiei cu virus hepatitic B Romanian J
Gastroenterology 2005; 14: 308-309
34. L Gheorghe, C Gheorghe, M Fleancu, I Popescu. Rezectia hepatica pentru carcinomul
hepatocelular . Romanian J Gastroenterology 2005; 14: 412-414
35. C Gheorghe. Narrow-band imaging endoscopy for diagnosis of malignant and
premalignant gastrointestinal lesions. J Gastrointestinal and Liver Diseases 2006; 15: 77-82
36. C Gheorghe, L Gheorghe, S Iacob, R Iacob, I Popescu. Primary prophylaxis of variceal
bleeding in cirrhotics awaiting liver transplantation. Hepato-Gastroenterology 2006; 53: 552-
557
37. C Gheorghe, C Stanescu, L Gheorghe, I Bancila, V Herlea, G Becheanu, DVoinea, I
Lupescu, R Anghel, A Croitoru, and I Popescu. The preoperative noninvasive EUS
evaluation in patients with esophageal cancer considered for esophagectomy. J
Gastrointestinal and Liver Diseases 2006; 15:137-141
38. Vasilescu C, Herlea V, Tudor S, Ivanov B, Stanciulea O, Manuc M, Gheorghe C,
Ionescu M, Diculescu M, Popescu I. Limfadenectomia D2 in chirurgia cancerului gastric.
Rezultate pe termen lung dupa analiza unei experiente de 227 de cazuri. Chirurgia 2006; 101:
375-384
39. C Gheorghe, L Gheorghe, G Becheanu, I Popescu. Tumora stromala gastrica: diagnostic
si tratament . J Gastrointestinal and Liver Diseases 2006; 15: 83-85
40. C Gheorghe, I Bancila, L Gheorghe, A Pitrop. Optiuni terapeutice in achalasie. J
Gastrointestinal and Liver Diseases 2006; 15: 195-197
41. L Gheorghe, S Iacob, C Gheorghe, I Lupescu. Upper gastrointestinal bleeding caused by
extrahepatic portal vein obstruction J Gastrointestinal and Liver Diseases 2006; 15: 280-282
42. C Angelescu, C Gheorghe, L Gheorghe, I Lupescu, VHerlea, M Ionescu. Pancreatic
neuroendocrine tumor . J Gastrointestinal and Liver Diseases 2006; 15: 403-405
43. L Gheorghe, S Iacob, I. Sporea, M. Grigorescu, R Sirli, D Damian, C. Gheorghe, R.
Iacob. Efficacy, tolerability and predictive factors for early and sustained virological
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response in patients treated with weight-based dosing regimen of PegIFN -2b and ribavirin
in real-life healthcare setting. J Gastrointestinal and Liver Diseases 2007; 16: 23-30
44. R Vadan, C. Gheorghe Pattern of relapses in Romanian patients with ulcerative colitis.
JGastrointestinal and Liver Diseases 2007; 16: 121-122
45. I Lupescu, M. Grasu, Mirela Boros, C. Gheorghe, M. Ionescu, I. Popescu, V. Herlea, S.
Georgescu. Gastrointestinal stromal tumors: retrospective analysis of the computer
tomographic aspects. JGastrointestinal and Liver Diseases 2007; 16: 147-152
46. C Gheorghe, R Iacob, I Bancila. Olympus capsule endoscopy for small bowel
examination. J Gastrointestinal and Liver Diseases 2007; 16: 309-314
47. L Gheorghe, S Iacob, R Iacob, C Gheorghe, I Popescu. Variation of MELD score as
predictor of death on the waiting list for liver transplantation. J Gastrointestinal and Liver
Diseases 2007; 16: 267-272
48. L Gheorghe, C Gheorghe, B Cotruta, A Carabela Computer Tomographic Aspects of
Gastrointestinal Stromal Tumors: Adding EUS and EUS Elastography to the diagnostic
tools. J Gastrointestinal and Liver Diseases 2007; 16: 346-347
49. I Lupescu, M. Grasu, G. Goldis, G. Popa, C. Gheorghe, C. Vasilescu. Computer
tomographic evaluation of digestive tract non-Hodgkin lymphoma. J Gastrointestinal and
Liver Diseases 2007; 16: 315-320
50. L Gheorghe, G. Becheanu, C. Gheorghe, A. Carabela, M Vasilica. An unusual cause of
hepatosplenomegaly and malabsorbtion J Gastrointestinal and Liver Diseases 2007; 16: 75-
76
51. C. Gheorghe, R. Iacob, I. Bancila, Doina Hrehoret. Ampullary bleeding diagnosed using
CCD high resolution and real time viewer capsule endoscope system J Gastrointestinal and
Liver Diseases 2007; 16: 187
52. C. Gheorghe, B. Cotruta, V. Trifu, M. Grasu, Liana Gheorghe. Perineal abscesses and
fistulas – always a mark of Crohn’s disease?. J Gastrointestinal and Liver Diseases 2007; 16:
307-308
53. S. Bataga, M. Tantau, C. Gheorghe, C. Stanciu, G. Constantinescu, A. Goldis, M. Strain,
E. D, A. Fraticiu, A. Saftoiu, C.J.J. Mulder. ERCP in Romania in 2006: a National
Programme seems mandatory. J Gastrointestinal and Liver Diseases 2007; 16: 431-436
54. C. Gheorghe, R. Iacob, G. Becheanu, M. Dumbrava. Confocal endomicroscopy for in
vivo microscopic analysis of upper gastrointestinal tract premalignant and malignant lesions.
J Gastrointestinal and Liver Diseases 2008; 17:95-100
55. C. Gheorghe, R. Iacob, L. Gheorghe. Projected Dynamics of Colonoscopic Screening
and Surveillance for Colorectal Cancer. Hepato-Gastroenterology 2008; 55: 1568-1572
56. Liana Gheorghe, Bogdan Cotruta, Viorel Trifu, Cristina Cotruta, Gabriel Becheanu,
Cristian Gheorghe. Drug-induced Sweet’s syndrome secondary to hepatitis C antiviral
therapy. International Journal of Dermatology 2008; 47: 957-959
57. Liana Gheorghe, Speranta Iacob, Cristian Gheorghe. Real-time Sonoelastography – a
New Application in the Field of Liver Disease. J Gastrointestin Liver Dis 2008; 17:469-474
58. A. Tonea, S. Andrei, D. Andronesi, M. Ionescu, C. Gheorghe, V. Herlea, Monica
Hortopan, Adriana Andrei, Andreea Andronesi, C. Popa, I. Popescu. Dificultati de diagnostic
si tratament chirurgical in angiodisplaziile tractului gastrointestinal. Chirurgia 2008; 103:
513-528
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59. S. Iacob, L. Gheorghe, R. Iacob, C. Gheorghe, D. Hrehoret, I. Popescu. Exceptiile
scorului MELD si un nou scor predictiv al decesului pe listele cu perioade lungi de asteptare
pentru transplantul hepatic. Chirurgia 2009; 104: 267-274
60. R. Iacob, P. Sarbu-Boeti, S. Iacob, S. Dima, C. Gheorghe, L. Gheorghe, I. Popescu.
Terapii cu celule stem in bolile hepatice si in afectiunile tubului digestiv. Chirurgia 2009;
104: 131-140
61. V. Tomulescu, O. Stanciulea, I. Balescu, S. Vasile, St. Tudor, C. Gheorghe, C.
Vasilescu, I. Popescu. Experienta primului an de chirurgie robotica – 153 de cazuri intr-un
departament de chirurgie generala: indicatii, tehnica si rezultate. Chirurgia 2009; 104: 141-
150
62. R. Vadan, L. Gheorghe, C. Gheorghe. Low prevalence and mild course of inflammatory
bowel diseases in South Eastern Europe. J Gastrointest Liver Dis 2009; 18: 385
63. C. Gheorghe, G. Becheanu, B. Cotruta, S. Suciu.: Endoscopic esophageal resection for
esophageal carcinoma as a complication of achalasia. J Gastrointest Liver Dis 2009; 18: 83
64. L. Gheorghe, S. Iacob, M. Grigorescu, I. Sporea, R. Sirli, D. Damian, C. Gheorghe, R.
Iacob. Therapy in genotype-1 patients with histologically mild hepatitis C. J Gastrointest
Liver Dis 2009; 18: 51-56
65. C. Gheorghe. Electroincision of anastomotic stricture after curative resection for gastric
cancer. J Gastrointest Liver Dis 2009; 18: 214
66. B. Cotruta, C. Gheorghe, I. Bancila. Magnifying endoscopy with narrow-band imaging
or confocal laser endomicroscopy for in vivo rapid diagnosis of Barrett’s esophagus. J
Gastrointest Liver Dis 2009; 18: 258
67. L. Gheorghe, S. Iacob, R. Iacob, M. Dumbrava, G. Becheanu, V. Herlea, C. Gheorghe, I.
Lupescu, I. Popescu. Real-time elastography – a non-invasive diagnostic method of small
hepatocellular carcinoma in cirrhosis. J Gastrointest Liver Dis 2009; 18 (4): 439-447
68. D. Andronesi, A. Andronesi, A. Tonea, S. Andrei, V. Herlea, I. Lupescu, C. Ionescu-
Targoviste, M. Coculescu, S. Fica, M. Ionescu, C. Gheorghe, I. Popescu. Insulinomul
pancreatic – analiza unei serii clinice de 30 de cazuri. Chirurgia 2009; 104: 675-685
69. G. Smira, L. Gheorghe, S. Iacob, D. Coriu, C. Gheorghe. Budd Chiari syndrome and
V617/JAK 2 mutation linked with mieloproliferative disorders. J Gastrointest Liver Dis
2010; 19 (1): 108-109
70. G. Smira, L. Gheorghe, C. Gheorghe, G. Becheanu, A. Croitoru . Multicentric
carcinomas of the gastrointestinal tract. J Gastrointest Liver Dis 2010; 19 (2): 204
71. V. Tomulescu, C. Gheorghe, D. Pitigoi, A. Cosa, M. Ciocirlan, D. Pietrareanu, F. Turcu,
C. Copaescu, G. Droc, H. Popescu, B. Grigorescu, O. Stanciulea, V. Herlea, I. Popescu.
Stabilirea modelului experimental de ooforectomie trnasgastrica pe model suin. Chirurgia
2010; 105: 331-337
72. I. Popescu, M. Ionescu, V. Brasoveanu, D. Hrehoret, E. Matei, B. Dorobantu, R. Zamfir,
S. Alexandrescu, M. Grigorie, D. Tulbure, L. Popa, M. Ungureanu, D. Tomescu, G. Droc, H.
Popescu, A. Cristea, L. Gheorghe, S. Iacob, C. Gheorghe, M. Boros, I. Lupescu, L. Vlad, V.
Herlea, M. Croitoru, P. Platon, A. Alloub. Transplantul hepatic – indicatii, tehnica, rezultate
– analiza unei serii clinice de 200 de cazuri. Chirurgia 2010; 105: 177-186
73. Liana Gheorghe, Irma Eva Csiki, Speranta Iacob, Cristian Gheorghe, Gabriela Smira,
Loredana Regep. The prevalence and risk factors of hepatitis C virus infection in adult
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population in Romania: A nationwide survey 2006-2008. J Gastrointestin Liver Dis 2010;
19: 373-380
74. Roxana Vadan, Liliana Simona Gheorghe, Alexandra Constantinescu, Cristian
Gheorghe. The prevalence of malnutrition and the evolution of nutritional status in patients
with moderate to severe forms of Crohn’s disease treated with Infliximab. Clinical Nutrition
2011; 30: 86-91
75. Adrian Saftoiu, Peter Vilmann, Florin Gorunescu, Jan Janssen, Michael Hocke, Michael
Larsen, Julio Iglesias-Garcia, Paolo Arcidiacono, Uwe Will, Marc Giovannini, Cristoph
Dietrich, Roald Havre, Cristian Gheorghe, Colin McKay, Dan Ionut Gheonea, Tudorel
Ciurea, on behalf of the European EUS Elastography Multicentric Study Group. Accuracy of
endoscopic ultrasound elastography used for differential diagnosis of focal pancreatic
masses: a multicentric study. Endoscopy 2011; 43 (7): 596-603
76. Nastase A, Paslaru L, Niculescu AM, Ionescu M, Dumitrascu T, Herlea V, Dima S,
Gheorghe C, Lazar V, Popescu I. Prognostic and predictive potential molecular biomarkers
in colon cancer. Chirurgia 2011; 106 (2): 177-185
77. Adrian Saftoiu, Peter Vilmann, Florin Gorunescu, Jan Janssen, Michael Hocke, Michael
Larsen, Julio Iglesias-Garcia, Paolo Arcidiacono, Uwe Will, Marc Giovannini, Cristoph
Dietrich, Roald Havre, Cristian Gheorghe, Colin McKay, Dan Ionut Gheonea, Tudorel
Ciurea, on behalf of the European EUS Elastography Study Group Efficacy of an Artificial
Neural Network Based Approach to Endoscopic Ultrasound Elastography in Diagnosis of
Focal Pancreatic Masses. Clin Gastroenterol Hepatol 2012; 10:84-90
78. Becheanu G, Gheorghe C, Dumbrava M, Serban-Barbu V, Diculescu M Inflammatory
myoglandular polyps: a series of seven cases and review of literature. Chirurgia
2011;106:613-617
79. Gheorghe C, Cotruta B, Iacob R, Becheanu G, Dumbrava M, Gheorghe L,
Endomicroscopy for assessing mucosal healing in patients with ulcerative colitis. J
Gastrointestin Liver Dis 2011; 20:423-426
80. Gologan S, Iacob R, Preda C, Vadan R, Cotruta B, Catuneanu AM, Iacob S,
Constantinescu I, Gheorghe L, Iobagiu S, Gheorghe C, Diculescu M. Higher titer of anti-
Saccharomyces cerevisiae antibodies IgA and IgG are associated with more aggressive
phenotypes in Romanian patients with Crohn’s disease. J Gastrointestin Liver Dis 2012; 21
(1): 39-44
81. Gheorghe L, Vadan R, Cerban R, Gheorghe C. Clostridium difficile infection in
gastroenterology settings: more frequent or better diagnosed ? J Gastrointestin Liver Dis
2012; 21 (1): 110-111
82. Iacob R, Iacob S, Nastase A, Vagu C, Ene AM, Constantinescu A, Anghel D, Banica C,
Paslaru L, Coriu D, Dima S, Gheorghe C, Ionica E, Gheorghe L. The His1069Gln mutation
in the ATP7B gene in Romanian patients with Wilson’s disease referred to a tertiary
gastroenterology center. J Gastrointestin Liver Dis 2012; 21 (2): 181-185
83. Cerban R, Gheorghe L, Becheanu G, Serban V, Gheorghe C. Primary focal T-cell
lymphoma of the liver: a case report and review of the literature. J Gastrointestin Liver Dis
2012; 21 (2): 213-216
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84. Rugina M, Predescu L, Salagean M, Gheorghe L, Gheorghe C, Tulbure D, Popescu I.
Bubenek-Turconi S. Pre-liver transplantation cardiac assessment. Chirurgia 2012; 107: 283-
290
85. Gheorghe C, Borca A, Gheorghe L. The role of EUS for accurate preoperative
differential diagnosis between GIST and pancreatic rest. J Gastrointestin Liver Dis 2012;
21(4): 442-443
86. Pirvulescu I, Gheorghe L, Csiki IE, Becheanu G, Dumbrava M, Fica S, Martin S, Sarbu
A, Gheorghe C, Diculescu M, Copaescu C. Noninvasive clinical model for the diagnosis of
nonalcoholic steatohepatitis in overweight and morbidly obese patients undergoing bariatric
surgery. Chirurgia 2012; 107(6): 772-779
87. Gheorghe C, Bancila I, Iacob R, Tomulescu V. Predictors of short term treatment
outcome in patients with achalasia following endoscopic surgical therapy.
Hepatogastroenterology 2012; 59 (120): 2503-2507
88. Stoiceascu A, Becheanu G, Dumbrava G, Gheorghe C, Diculescu M. Microscopic colitis
– a missed diagnosis in diarrhea-predominant irritable bowel disease. Maedica (Bucharest)
2012; 7 (1): 3-9
89. Gheorghe L, Csiki IE, Iacob S, Gheorghe C. Epidemiology of hepatitis B virus infection
in general population in Romania: a nationwide survey. Eur J Gastroenterol Hepatol 2013;
25(1): 56-64.
90. Gheorghe C, Pascu O, Iacob R, Vadan R, Iacob S, Goldis A, Tantau M, Dumitru E,
Dobru D, Miutescu E, Saftoiu A, Fraticiu A & Gheorghe L. Nutritional risk screening and
prevalence of malnutrition on admission to gastroenterology departments: a multicentric
study. Chirurgia 2013; 108: 535-541
91. Gheorghe L, Iacob S, Iacob R, Smira G, Pietrareanu C, Hrehoret D, Brasoveanu V,
Gheorghe C, Popescu I. Dynamics of the Romanian waiting list for liver transplantation after
changing organ allocation policy. J Gastrointest Liver Dis 2013; 22: 299-303
92. Iacob R, Iacob S, Gheorghe L, Gheorghe C, Hrehoret D, Brasoveanu V, Croitoru A,
Herlea V, Popescu I. Outcome of liver transplantation for hepatocellular carcinoma – a single
center experience. Chirurgia 2013; 108: 446-450
93. Gologan S, Iacob R, Iancu D, Iacob S, Cotruta B, Vadan R, Catuneanu AM,
Constantinescu I, Barbarii L, Gheorghe C, Diculescu M. Inflammatory gene expression
profile in Crohn’s disease and ulcerative colitis: a comparative analysis using a reverse-
transcriptase multiplex ligation-dependent probe amplification protocol. J Crohns Colitis
2013; 7 (8): 622-630
94. Lucian Negreanu, Simona Bataga, Cristina Cijevschi-Prelipcean, Daniela Dobru, Mircea
Diculescu, Eugen Dumitru, Dan Ionut Gheonea, Liana Gheorghe, Cristian Gheorghe,
Adrian Goldis, Bogdan Mateescu, Marcel Tantau, Anca Trifan. Excellence Centers in
Inflammatory Bowel Disease in Romania: a Measure of the Quality of Care. J Gastrointestin
Liver Dis 2014; 23 (3): 333-337
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95. Dumitrascu D, Chira A, Bataga S, Diculescu M, Drug V, Gheorghe C, Goldis A,
Nedelcu L, Porr PJ, Sporea I for the Romanian Society of Neurogastroenterology. The use of
mebeverine in irritable bowel syndrome. A Position Paper of the Romanian Society of
Neurogastroenterology based on evidence. J Gastrointestin Liver Dis 2014; 23: 431-435
96. Lupu A, Diculescu M, Diaconescu R, Tantau M, Tantau A, Visovan I, Gheorghe C, Lupei
C, Gheorghe L, Cerban R, Vadan R, Goldis A. prevalence of anemia and iron defficiency in
Romanian patients with inflammatory bowel disease: A prospective multicenter study. J
Gastrointestin Liver Dis 2015; 24: 15-20
97. Gheorghe C, Seicean A, Saftoiu A, Tantau M, Dumitru E, Jinga M, Negreanu L,
Mateescu B, Gheorghe L, Ciocirlan M, Cijevschi C, Constantinescu G, Dima S, Diculescu M.
Romanian Guidelines on the diagnosis and treatment of exocrine pancreatic insufficiency. J
Gastrointestin Liver Dis 2015; 24: 117-123
98. Gheorghe L, Csiki IE, Iacob S, Gheorghe C, Trifan A, Grigorescu M, et al. Hepatitis
delta virus infection in Romania: Prevalence and risk factors. J Gastrointestin Liver Dis
2015; 24: 413-422
99. Zaharie R, Tantau A, Zaharie F, Tantau M, Gheorghe L, Gheorghe C, et al, on behalf of
the IBDPROSPECT Study Group.Diadnostic delay in Romanian patients with inflamatory
bowel disease:risk factors and impact on the disease course and need for surgery. JCC 2016;
10 (3): 306-314.
100. Iacob R, Dimitriu A, Stanciulea O, Herlea V, Popescu I, Gheorghe C. Enteroscopic
tattooing for better intraoperative localization of a bleeding jejunal GIST facilitates
minimally invasive laparoscopically-assisted surgery. J Gastrointestin Liver Dis 2016;
25(1):105-108
101. Dimitriu A, Iacob R, Nicula S, Cojocaru M, Gheorghe C, Diculescu M, Gheorghe L.
Causes of hospitalization and characteristics of UC in a population-based cohort in Romania
(2014-2015): Are there any differences in comparison with the Hungarian population? J
Gastrointestin Liver Dis 2016; 25 (1): 121-122.
102. Cotruta B, Becheanu G, Iacob R, Gheorghe C. The orientation of the gastric biopsy
specimen for the gastric atrophy assessment is important. J gastrointestin Liver Dis 2016;
25(1):123-124.
103. Bancila I, Popescu I, Herlea V, Becheanu G, Dumbrava M, Gheorghe C. Menetrier’s
disease: A rare entity which mimics gastric cancer. J Gastrointestin Liver Dis 2016;
25(2)137.
104. Preda CM, Fulger LE, Gheorghe C, Gheorghe L, Manuc M, Negreanu L, Meianu C,
Slavulete BI, Diculescu MM. Tuberculin skin test and Quantiferon TB Gold Test in
Romanian BCG vaccinated, immunosuppressed patients with moderate-to-severe Crohn’s
disease: A comparison with a Hungarian cohort. J Gastrointestin Liver Dis 2016; 25(2): 260-
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