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Data ManagementData Management andand
Biostatistics FacilitiesBiostatistics Facilitiesby
Ammarin Thakkinstian
Data ManagementData ManagementSection for Clinical Epidemiology and BiostatisticsSection for Clinical Epidemiology and Biostatistics,
Faculty of Medicine Ramathibodi Hospital (CEB-RAMA)
AND
Center of Excellence for Biomedical and Public HealthCenter of Excellence for Biomedical and Public Health
Informatics (BIOPHICS)
Faculty of Tropical Medicine
Mahidol University y
Roles & ResponsibilitiesRoles & Responsibilities• Study PreparationsStudy Preparations
Modify questionnaire format to comply with the DataFax softwareSetup databasesSetup databases Construct data-quality checking program for data quality-control
• Quality AssuranceQuality AssuranceEnter data to DataFax system
Validate data to source documentValidate data to source documentCheck quality of entered dataGenerate quality control reportq y pTransfer data for analysisLock database for data submission
TimelinesTimelinesD t C ll ti @ 4 EGAT it• Data Collection @ 4 EGAT sites
July – Oct 2013• Data Management @ BIOPHICS & CEB-Rama
Aug 2013 – Jan 2014Aug 2013 Jan 2014• EGAT Web-databases
F b A il 2014Feb – April 2014
EGAT Data Work FlowQuestionnaire
Questionnaire
Questionnaire Checking
Questionnaire sequencingRama-CEB &
BIOPHIC
Data delivery
Scan individual binder
DataFaxServer
Data Validation in DataFax System
Import to DataFax system
Insert DataFaxbarcode & save as pdf
Save as pdf
Data Validation Work Flow for DataFax Systemfor DataFax System
New questionnaires in DataFax format are in place
Final data validation & QC @ BIOPHICS & CEB-RAMA
Initial data validation @ BIOPHICS
QC @ BIOPHICS & CEB-RAMA
Data are validated until
Data verification
Data exportation
they are cleaned
Sites are able to view/enter/edit questionnaires online
verification @ site
DataFaxServer
Web-database
sDi
Sites are able to view/enter/edit questionnaires online
ssDisc Storage
Tape Backup
CEB-RamaCEB-RamaC• 3 Clinical Epidemiologists
• 7 Biostatisticians• 7 Biostatisticians• 1 Programmer
FacilitiesFacilities • Data management
– EGAT-Webdatabases– Retrieve data
R t f d t• Request for data– WWW.ceb-rama.org
• Lodge application form• Lodge application form – Contact
• Dittapol Muntham• Dittapol Muntham– Email: [email protected]– Tel: 022011269, 022011284Tel: 022011269, 022011284
Numbers of subject for EGAT2-2013
Site Expected Actual pN N
Bang Kruay 1438 1428Bang Kruay 1438 1428Srinagarind Dam 250 214Vajiralongkorn Dam 130 116Bh ibh l D 250 259Bhumibhol Dam 250 259Total 2068 2017
Data QC
FacilitiesFacilities • Data analysis
– Linear regressionLinear regression – Fractional polynomial regression – Logistic regression
Survival analysis– Survival analysis – Longitudinal data analysis – Survey data analysis
M t l i– Meta-analysis – Analysis for genetic association studies
• Request for data analysis – Contact
• Wipada Purawat– Email: [email protected]– Tel: 022011269, 022011284
Thank you
