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Delaware Membrane Protein Symposium http://www.che.udel.edu/cobre/symposium.html John M. Clayton Hall, University of Delaware, Newark, Delaware Monday, October 6, 2008 AGENDA 8:30 - 8:40 am Welcome Brian Bahnson Presiding 8:40 - 9:20 am David Cafiso (University of Virginia) “Solutes and Membrane Environment Modify Membrane Protein Structure and Dynamics” 9:20 - 10:00 am Wonhwa Cho (University of Illinois at Chicago) “Spatiotemporal Regulation of Cellular Processes by Lipids and Lipid-Binding Proteins: Proteomics and Single Molecule Studies” 10:00 - 10:20 am Coffee Break Tatyana Polenova Presiding 10:20 - 11:00 am Judith Klein-Seetharaman (University of Pittsburgh) “Anthocyanins and Chlorophylls – Modulators of the Dynamics, Stability and Function of the Prototypic G Protein Coupled Receptor Rhodopsin” 11:00 - 11:40 am Chuck Sanders (University of Virginia) “Structure of the Transmembrane Amyloid Precursor Protein - Is APP a Cholesterol Sensor” 11:40 - 12:20 pm Emad Tajkhorshid (University of Illinois) “Dynamics of Active Transport Across Cellular Membranes at Full Atomic Resolution” 12:20 - 1:10 pm Lunch 1:10 - 2:30 pm Poster Session Sharon Rozovsky Presiding 2:30 - 3:10 pm Erin Sheets (Penn State University) “Imaging Membrane Dynamics Participating in Immunoreceptor Signaling” 3:10 - 3:50 pm Lukas Tamm (University of Virginia) “Domain Coupling in Asymmetric Lipid Bilayers” 3:50 - 4:10 pm Coffee Break 4:10 - 5:00 pm Keynote Lecture - Zoshua Zimmerberg (National Institutes of Health) Exocytotic and Viral Membrane Fusion, Fission, and Assembly: What do Proteins do and When do Lipids Matter?

Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

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Page 1: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

Delaware Membrane Protein Symposium http://www.che.udel.edu/cobre/symposium.html John M. Clayton Hall, University of Delaware, Newark, Delaware Monday, October 6, 2008

AGENDA

8:30 - 8:40 am Welcome

Brian Bahnson Presiding

8:40 - 9:20 am David Cafiso (University of Virginia) “Solutes and Membrane Environment Modify Membrane Protein Structure and Dynamics”

9:20 - 10:00 am Wonhwa Cho (University of Illinois at Chicago)

“Spatiotemporal Regulation of Cellular Processes by Lipids and Lipid-Binding Proteins: Proteomics and Single Molecule Studies”

10:00 - 10:20 am Coffee Break

Tatyana Polenova Presiding

10:20 - 11:00 am Judith Klein-Seetharaman (University of Pittsburgh)

“Anthocyanins and Chlorophylls – Modulators of the Dynamics, Stability and Function of the Prototypic G Protein Coupled Receptor Rhodopsin”

11:00 - 11:40 am Chuck Sanders (University of Virginia)

“Structure of the Transmembrane Amyloid Precursor Protein - Is APP a Cholesterol Sensor”

11:40 - 12:20 pm Emad Tajkhorshid (University of Illinois) “Dynamics of Active Transport Across Cellular Membranes at Full Atomic Resolution”

12:20 - 1:10 pm Lunch

1:10 - 2:30 pm Poster Session

Sharon Rozovsky Presiding

2:30 - 3:10 pm Erin Sheets (Penn State University)

“Imaging Membrane Dynamics Participating in Immunoreceptor Signaling”

3:10 - 3:50 pm Lukas Tamm (University of Virginia) “Domain Coupling in Asymmetric Lipid Bilayers”

3:50 - 4:10 pm Coffee Break

4:10 - 5:00 pm Keynote Lecture - Zoshua Zimmerberg (National Institutes of Health)

Exocytotic and Viral Membrane Fusion, Fission, and Assembly: What do Proteins do and When do Lipids Matter?

Page 2: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

University of Delaware Membrane Protein Symposium

Date: Wednesday, November 11, 2009 – 8:30 a.m.

Venue: Clayton Hall, University of Delaware, Newark, Delaware

Session Time Speaker Opening 8:30 – 8:35 am Opening Remarks (Symposium Organizers) Symposium 8:35 – 9:20 am Toby Allen (University of California - Davis)

Membrane Ion Permeability and Channel Function Explored with Atomistic Simulation

9:20 – 10:05 am Francesco Tombola (University of California - Irvine) The Voltage-Sensing Domain (VSD) and VSD-Containing Proteins

Coffee Break 10:05 – 10:25 am Symposium 10:25 – 11:10 am Joanne Yeh (University of Pittsburgh)

Structural Studies of Glycerol-3-Phosphate Dehydrogenase: A Monotopic Membrane Enzyme Functioning at the Junction Between Essential Metabolic Pathways and Respiration

11:05 – 11:50 am Barbara Baird (Cornell University) Plasma Membrane Heterogeneity and Receptor Mediated Signaling

Lunch 11:50 – 12:50 pm Poster session 12:30 – 1:45 pm Symposium 1:45 – 2:30 pm Bridget Wilson (University of New Mexico)

Insights into the Spatiotemporal Regulation of Receptor Signaling via Combined High Resolution Imaging Techniques

2:30 – 3:15 pm Thomas Sakmar (Rockefeller University) Heptahelical Receptors: Ligand Recognition and Conformational Dynamics in Bilayers

Break 3:15 – 3:30 pm 3:30 – 4:15 pm Peter Tieleman (University of Calgary)

Computer Simulations of Transmembrane Helices Plenary (Keynote)

4:15 – 5:15 pm Donald Engelman (Yale University) From Folding to pHLIP: a Voyage of Discovery

Adjourn 5:15 pm

Page 3: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR

Meeting Agenda

Time Speaker Room

8:30 – 8:35 am Opening Remarks 101-B

8:35 – 9:15 am Vinzenz Unger – Northwestern University

“When Structures Talk – A Tale About Trimers, Threesomes and A Slippery Surface”

101-B

9:15 – 9:55 am Debra A. Kendall – University of Connecticut “A Tale of Two Philicities: The Cannabinoid Receptor Caroxyl-Terminus”

101-B

9:55 – 10:15 am Break Lobby

10:15 – 10:55 am Tamas Balla – National Institutes of Health

“Detection and Rapid Manipulation of Phosphoinositides with Engineered Molecular Tools”

101-B

10:55 – 11:35 am A. Alia – University of Leiden “Direct Access to the Heart of Photosystem II Protein Complex by Photo-CIDNP Solid-State NMR”

101-B

11:35 am – 12:15 pm Petra Fromme – Arizona State University “Femtosecond Nanocrystallography of Membrane Proteins”

101-B

12:15 – 2:00 pm Lunch 101-A

12:45 – 2:00 pm Poster Session Lobby

2:00 – 2:40 pm Michael Brown – University of Arizona “Solid-State 2H NMR Relaxation Establishes Functional Dynamics of Retinal in Activation Mechanism of Membrane-Bound Rhodopsin”

101-B

2:40 – 3:20 pm Tobias Walther – Yale University “The Phase of Fat: the Cell Biology of Lipid Droplets”

101-B

3:20 – 4:00 pm Joerg Matysik – University of Leiden “The Solid-State Photo-CIDNP Effect”

101-B

4:00 – 4:15 pm Break Lobby

4:15 - 5:15 pm KEYNOTE SPEAKER George Vann Bennett – Duke University “A Conserved Ankyrin-Based Mechanism for Assembly of Diverse Specialized Membrane Domains”

101-B

Delaware Membrane Protein Symposium May 4, 2011

8:30 a.m.

Clayton Hall

Newark, DE

Page 4: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

Delaware Membrane Protein Symposium

Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

Time Speaker Room

8:30 – 8:35 am Opening Remarks 101-B

8:35 – 9:15 am Vinzenz Unger – Northwestern University

“When Structures Talk – A Tale About Trimers, Threesomes and A Slippery Surface”

101-B

9:15 – 9:55 am Debra A. Kendall – University of Connecticut “A Tale of Two Philicities: The Cannabinoid Receptor Caroxyl-Terminus”

101-B

9:55 – 10:15 am Break Lobby

10:15 – 10:55 am Tamas Balla – National Institutes of Health

“Detection and Rapid Manipulation of Phosphoinositides with Engineered Molecular Tools”

101-B

10:55 – 11:35 am A. Alia – University of Leiden “Direct Access to the Heart of Photosystem II Protein Complex by Photo-CIDNP Solid-State NMR”

101-B

11:35 am – 12:15 pm

Petra Fromme – Arizona State University “Femtosecond Nanocrystallography of Membrane Proteins”

101-B

12:15 – 2:00 pm Lunch 101-A

12:45 – 2:00 pm Poster Session Lobby

2:00 – 2:40 pm Michael Brown – University of Arizona “Solid-State 2H NMR Relaxation Establishes Functional Dynamics of Retinal in Activation Mechanism of Membrane-Bound Rhodopsin”

101-B

2:40 – 3:20 pm Tobias Walther – Yale University “The Phase of Fat: the Cell Biology of Lipid Droplets”

101-B

3:20 – 4:00 pm Joerg Matysik – University of Leiden “The Solid-State Photo-CIDNP Effect”

101-B

4:00 – 4:15 pm Break Lobby

4:15 - 5:15 pm KEYNOTE SPEAKER George Vann Bennett – Duke University “A Conserved Ankyrin-Based Mechanism for Assembly of Diverse Specialized Membrane Domains”

101-B

May 4, 2011 8:30 a.m. Clayton Hall Newark, DE

Page 5: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

Sponsored by the COBRE on Membrane Protein Production & Characterization

Supported by NIGMS

Meeting Agenda Monday, April 29, 2013

Time Speaker Room

8:00 – 8:55 Registration, Breakfast, and Poster Set-Up Lobby

9:00 – 9:10 am Opening Remarks 101-B

9:10 – 9:50 am Tamir Gonen – Howard Hughes Medical Institute

“The Influence of Lipids on Membrane Protein Structure and Function”

101-B

9:50 – 10:30 am Jack Freed – Cornell University

“Electron-Spin Resonance in the Study of Membranes and Membrane

Proteins”

101-B

10:30 – 10:50 am Break & Poster Session Lobby

10:50 – 11:30 am Sarah Veatch – University of Michigan

“Lipid Rafts Reach a Critical Point”

101-B

11:30 am – 12:10 pm Michael Wolfe – Harvard Medical School

“Proteolytic Functions of Gamma-Secretase and Implications for Alzheimer’s

Disease”

101-B

12:10 – 1:30 pm Lunch 101-A

12:30 – 2:00 pm Poster Session Lobby

2:00 – 2:40 pm Hidde Ploegh – Massachusetts Institute of Technology

“Bacteria and Viruses as a Source of Tools for the Biochemist”

101-B

2:40 – 3:20 pm Alan Grossfield – University of Rochester Medical Center

“Multiscale Modeling of G Protein-Coupled Receptors”

101-B

3:20 – 4:00 pm Brian Fox – University of Wisconsin-Madison

“Membrane Proteins from Cell-Free Translation”

101-B

4:00 – 4:15 pm Break & Poster Session Lobby

4:15 - 5:15 pm KEYNOTE SPEAKER

Ann McDermott – Columbia University

“Ion Binding, Dynamics and Allostery in K+ Channels: NMR Studies of KcsA”

101-B

Delaware Membrane Protein Symposium

Page 6: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by the National Institute of General Medical Sciences (NIGMS), NIH

Meeting Agenda Monday, May 4, 2015

Time Speaker Room

8:00 – 8:55 am Registration, Breakfast, and Poster Set-Up Lobby

9:00 – 9:10 am Opening Remarks 101-B

9:10 – 9:50 am Ilya Levental – The University of Texas Health Science Center at

Houston

"What’s in a Raft? The Composition and Function of Plasma

Membrane Domains"

101-B

9:50 – 10:30 am Paulo Almeida – University of North Carolina Wilmington

"Lipid Interactions in Membranes" 101-B

10:30 – 10:50 am Break & Poster Session Lobby

10:50 – 11:30 am Suzanne Scarlata – Stony Brook University Medical Center

"Regulation of Cell Function through Membrane Domains Called

Caveolae"

101-B

11:30 am – 12:10 pm Elina Ikonen – University of Helsinki

“LAPTM4B Facilitates Late Endosomal Ceramide Export to Control

Sphingolipid Mediated Cell Death Pathways"

101-B

12:10 – 1:30 pm Lunch 101-A

12:30 – 2:00 pm Poster Session Lobby

2:00 – 2:40 pm Maurine Linder – Cornell University

“Mechanism and Function of DHHC Palmitoyltransferases" 101-B

2:40 – 3:20 pm Martin Forstner – Syracuse University

"Structure and Mechano-Biology of the Non-Erythroid Membrane

Skeleton"

101-B

3:20 – 4:00 pm Ron Dror – Stanford University

“Revealing Structural Dynamics of GPCR Signaling through Atomic-

Level Simulation"

101-B

4:00 – 4:15 pm Break & Poster Session Lobby

4:15 - 5:15 pm KEYNOTE SPEAKER: Stephen White – University of California at Irvine

"Membrane Protein Folding: Biology Meets Thermodynamics" 101-B

Delaware Membrane Protein Symposium

Page 7: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

www.che.udel.edu/cobre/symposium

M o n d a y, A p r i l 1 8 , 2 0 1 6

DELAWARE MEMBRANEPROTEIN SYMPOSIUM

CLAYTON HALL CONFERENCE CENTERUniversity of Delaware

INVITED SPEAKERS

Gisela Storz. . . . . . . National Institute of Child Health and Human Development

KEYNOTE SPEAKER

Marius Lemberg Zentrum für Molekulare Biologie der Universität Heidelberg

REGISTRATION & POSTER SUBMISSIONOn-line registration is available on our website at http://sites.udel.edu/cobre/symposia/2016-symposium until April 8, 2016. Admission is free, but registration is required.

Poster submissions are welcomed and can be submitted to Kristi Halberg at [email protected] by April 8, 2016.

Peter Kasson. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . University of Virginia

Chad Rienstra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . University of Illinois

Anne Robinson. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Tulane University

Janice Robertson. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . University of Iowa

Arnd Pralle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . University at Buffalo, SUNY

Filip Van Petegem . . . . . . . . . . . . . . . . . . . . . . . University of British Columbia

Organized by Sharon Rozovsky, Edward Lyman and Karen Fleming

Page 8: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda
Page 9: Delaware Membrane Protein Symposium · Delaware Membrane Protein Symposium Sponsored by the COBRE on Membrane Protein Production & Characterization Supported by NIH/NCRR Meeting Agenda

DELAWARE MEMBRANEPROTEIN SYMPOSIUM

T h e 2 0 1 8 S y m p o s i u m i s d e d i c a t e d t o t h e m e m o r y o f o u r c o l l e a g u e M a h e n d r a J a i n

Monday, April 30, 2018CLAYTON HALL CONFERENCE CENTER

University of DelawareOrganized by Sharon Rozovsky, Edward Lyman and Karen Fleming

KEYNOTE SPEAKERMary RobertsBoston College

SPEAKERSJeffrey Brodsky .......................................................................................................................... University of PittsburghLuke Chao ................................................................. Massachusetts General Hospital, Harvard Medical SchoolJennifer Lee ......................................................................................................... National Institutes of Health, NHLBIPatrick Loll ................................................................................................................................................ Drexel UniversityJeffery Klauda .............................................................................................................................. University of MarylandJoseph Mindell .................................................................................................. National Institutes of Health, NINDSNoah Malmstadt ..................................................................................................... University of Southern California

REGISTRATION & POSTER SUBMISSIONAdmission is free, but registration is required. On-line registration is available on our website until Friday,April 20, 2018: http://www.che.udel.edu/2018_DEMP_Symposium/Poster submissions are welcomed and can be submitted to Kristi Halberg: [email protected] by Friday,April 20, 2018.

http://www.che.udel.edu/2018_DEMP_Symposium/The University of Delaware does not discriminate against any person on the basis of race, color, national origin, sex, gender identity or expression, sexual orientation, genetic information, marital status, disability, religion, age, veteran status or any other characteristic protected by applicable law in its employment, educational programs and activities, admissions policies, and scholarship and loan programs as required by Title IX of the Educational Amendments of 1972, the Americans with Disabilities Act of 1990, Section 504 of the Rehabilitation Act of 1973, Title VII of the Civil Rights Act of 1964, and other applicable statutes and University policies. The University of Delaware also prohibits unlawful harassment including sexual harassment and sexual violence. For inquiries or complaints related to non-discrimination policies, please contact: Susan L. Groff, Ed.D. Director, Institutional Equity & Title IX Coordinator, 305 Hullihen Hall, Newark, DE 19716, (302) 831-8063. [email protected]