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Department of Pharmaceutics
Courses Specifications
2017-2018
1 | P a g e
Contents
Orientation to pharmacy .................................................................................... 2
Pharmaceutical calculations ............................................................................... 6
Pharmaceutics-1 ................................................................................................ 10
Pharmaceutics-2 ................................................................................................ 16
Physical pharmacy ............................................................................................ 22
Biopharmaceutics and Pharmacokinetics ....................................................... 27
Drug Delivery Systems and Targeting ............................................................ 33
Pharmaceutical Technology-1 .......................................................................... 37
Pharmaceutical Technology-2 .......................................................................... 42
Radiopharmaceutics .......................................................................................... 48
Fundamentals of Cosmetology ......................................................................... 53
Dosage form design ........................................................................................... 56
2 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Orientation to pharmacy
Course Code: PH 101
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Fall Semester 2017/2018 Level one
Prerequisite: None
Credit hours: Lecture: 1 Practical: 0 Total: 1
2. Course Aims:
To provide student with knowledge about the principles of basics and ethics of pharmacy
practice; recognize the different types of pharmaceutical dosage forms and drug delivery
systems. In addition to knowledge about different types of prescriptions. Describe the
different pharmacy careers and the role of pharmacist in each. Recognize international and
national pharmaceutical organizations. Know simple idea about history and development of
pharmacy profession.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A21
a1. Describe the principles of basics and ethics of pharmacy practice
a2.
Identify the different pharmacy careers and role of pharmacist as a member
in health care team in community, hospital, governmental, military
pharmacies and pharmaceutical industries.
a3. Summarize the different pharmaceutical dosage forms and drug delivery
systems, routes of drug administration and different types of prescriptions.
a4. Recognize international and national pharmaceutical organizations.
a5. Outline the history and development of pharmacy profession.
b. Intellectual Skills:
At the end of this course, student should be able to:
B1 b1. Specify the role of pharmacist in different pharmaceutical organizations
B4 b2. Assess different types of prescriptions and how to deal with each type.
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C1 c1. Utilize pharmaceutical and medical terms properly
3 | P a g e
c2 Collect pharmaceutical data about drugs from reliable information sources
d. General and Transferable Skills:
At the end of this course, student should be able to
D3 d1. Work effectively as a part of a team
D9 d2 Manage time effectively
4. Contents:
4.1. Lectures:
4.2. Practical: N/A.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. LMS
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
3. Oral exam To assess knowledge, understanding, intellectual skills, and general
skills.
Study
week Topics
No. of
Credit Hours
1. Introduction for pharmacy ethics and pharmacy career 1
2. International and local pharmaceutical organizations 1
3. Role of pharmacist in different pharmaceutical work areas 1
4. Types and properties of oral dosage forms + Quiz 1 1
5. Types and properties topical dosage forms 1
6. Types and properties of sterile dosage forms 1
7. Primary and secondary sources of pharmaceutical
information 1
8. Quiz 2
9. Types of prescriptions 1
10. Narcotic prescriptions 1
11. Routes of administrations 1
12. History of pharmacy profession 1
13. History of pharmacy profession 1
14. Final Exam
Total:
1 credit hours 15.
4 | P a g e
4. Quizzes To assess knowledge, understanding and intellectual skills.
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity all over the term
Assessment 4 Oral exam 14th &15th weeks
Assessment 5 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (research) 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
7. List of References:
No. Reference Type
1.
Allen, Loyd, and Howard C. Ansel's pharmaceutical dosage forms
and drug delivery systems. Lippincott Williams & Wilkins,
Philadelphia, 2013.
textbook
2.
Aulton, Michael E., and Kevin MG Taylor, eds. Aulton's
Pharmaceutics E-Book: The Design and Manufacture of
Medicines. Elsevier Health Sciences, 2017.
textbook
3. https://aihp.org/historical-resources/teaching-the-history-of-
pharmacy website
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction for pharmacy ethics and
pharmacy career a1,a4 -- c1 --
2. International and local
pharmaceutical organizations a4 -- c1 --
3. Role of pharmacist in different
pharmaceutical work areas a2 -- c1, c2 d1, d2
4. Types and properties of oral dosage
forms a3 b1 c1 d1, d2
5 | P a g e
5. Types and properties topical dosage
forms a3 b1 c1 d1, d2
6. Types and properties of sterile dosage
forms a3 b1 c1 d1, d2
7. Primary and secondary sources of
pharmaceutical information a3 -- c2 d1, d2
9. Types of prescriptions a1, a2,a3 b2 c1, c2 d1, d2
10. Narcotic prescriptions a1, a2,a3 b2 c1, c2 d1, d2
11. Routes of administrations a3 b2 c1 d1, d2
12. History of pharmacy profession a4 -- -- d1, d2
13. History of pharmacy profession a4 -- -- d1, d2
Name Signature
Course Coordinator: Dr. Enas Ibrahim El Zahaby
Head of Department: Prof. Dr. Ahmed Talaat Nouh
Approval Date 29/8/2017
6 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmaceutical calculations
Course Code: PH 211
Program on which the course is given: B. Pharm.
Department offering the course: pharmaceutics
Academic year/ level: Fall Semester 2017/2018 Level two
Prerequisite: Mathematics (PC 101)
Credit hours: Lecture:2 Practical: 0 Total:2
2. Course Aims:
To provide the student with the knowledge and skills required of pharmaceutical calculations
to perform different mathematical treatments required for dose calculations and preparation
of different dosage forms.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A17
a1. Define the different measuring systems used in pharmacy
a2. Outline the different methods of calculations involved in preparation of
pharmaceutical products
a3. State equivalent measures between the international system of units and
other systems of measure used in pharmacy practice
a4. Describe different approaches for calculation of pediatric and adult doses
a5. Illustrate the bases of dose adjustment
b. Intellectual Skills:
At the end of this course, student should be able to:
B10
b1. Convert measures between the international system and other systems of
measure used in pharmacy
b2. Calculate the proper dose of drugs for adults and pediatrics
b3. Calculate the proper dose of chemotherapeutic agents
b4. Specify the bases of dose adjustment
7 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C3
c1. Apply the international system of units correctly in calculations
c2. Perform basic calculations for preparation of different pharmaceutical
formulations
c3 Perform calculations for the preparation and use of stock solutions.
c4 Apply alligation medial and alligation alternate in problem-solving
d. General and Transferable Skills:
At the end of this course, student should be able to:
D1 d1. Communicate effectively with other health care professionals
D3 d2. Work effectively as a part of a team
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1. Fundamentals of pharmaceutical measurements and
calculations 2
2. Metric and common system 2
3.
Interpretation of prescription or medication order
1) The apothecariesˋ
2) Avoirdupois measures
3) Household measures
Reducing and enlarging formulas
2
4. Density, specific gravity and specific volume + Quiz 1 2
5. Weight and volume of liquids and percentage preparation 2
6. Ratio strength
Simple conversion from percentage to ratio strength 2
7. Dilution and concentration 2
8. Quiz 2
9. Stock solution
Dilution of alcohol 2
10. Allegation medial 2
11. Allegation alternate 2
12. Calculation of pediatric dose according to body weight, age
and body surface area 2
13. Calculation of chemotherapeutic dose according to body
weight, age and body surface area 2
14. Final Exam
Total:
2 credit hours 15.
8 | P a g e
4.2. Practical: N/A
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Home work
5.3 LMS
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
3. Quizzes To assess knowledge, understanding and intellectual skills.
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (make a summary of the
course problems and solving examples) all over the term
Assessment 4 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (make a summary of the
course problems and solving examples) 5
2. Final-Term Exam 75
Total 100%
7. List of References:
No. Reference Type
1.
Allen, Loyd, and Howard C. Ansel's pharmaceutical dosage forms
and drug delivery systems. Lippincott Williams & Wilkins,
China, 2013.
textbook
2. Robert M. Fulcher and Eugenia M. Fulcher. Pharmaceutical
Calculations. Elsevier, First Edition, China, (2014), textbook
9 | P a g e
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Fundamentals of pharmaceutical
measurements and calculations a1, a2 b1 c1 --
2. Metric and common system a3 b1, b2 c1 --
3.
Interpretation of prescription or
medication order
4) The apothecariesˋ
5) Avoirdupois measures
6) Household measures
Reducing and enlarging formulas
a2, a3 b1, b2 c1 d1, d2
4. Density, specific gravity and specific
volume a1, a2 b1 c1 d1, d2
5. Weight and volume of liquids and
percentage preparation a2, a3 b1 c1 d1, d2
6.
Ratio strength
Simple conversion from percentage to
ratio strength
a1, a2,
a3 b1, b2 c1, c2 d1, d2
7. Dilution and concentration a2, a3 b1, b2 c1, c2 d1, d2
9. Stock solution
Dilution of alcohol a2, a3 b1, b2
c1, c2,
c3 d1, d2
10. Allegation medial a1, a2,
a3 b1, b2
c1, c2,
c4 d1, d2
11. Allegation alternate a1, a2,
a3 b1, b2
c1, c2,
c4 d1, d2
12.
Calculation of pediatric dose according
to body weight, age and body surface
area
a4, a5 b2, b3,
b4 c1 d1, d2
13.
Calculation of chemotherapeutic dose
according to body weight, age and body
surface area
a2, a4,
a5
b2, b3,
b4 c1 d1, d2
Name Signature
Course Coordinator: Dr. Enas Ibrahim
Head of Department: Prof. Dr. Ahmed Talaat Nouh
Approval Date 29/8/2017
11 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmaceutics-1
Course Code: PH 212
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Spring Semester 2017/2018 Level one
Prerequisite: Orientation to Pharmacy (PH 101)
Credit hours: Lecture: 2 Practical: 1 Total: 3
2. Course Aims:
To provides the students with the basic physicochemical principles in the formulation and
preparation of liquid dosage forms used via the different routes of administration. Methods of
preparation and evaluation of solution and suspension and emulsions, creams and ointments.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A2 a1. Define the properties of different types of liquid and semisolid dosage forms
A6
a2. Describe the different types of solutions, suspension, emulsion, colloids and
semisolids.
a3. Recognize the differences between solution, suspensions and emulsions as
an example for dispersed system.
A22 a4. Summarize the proper pharmaceutical terminology and abbreviations used in
formulation of liquid and semisolid dosage forms.
b. Intellectual Skills:
At the end of this course, student should be able to:
B4
b1. Apply Stoke, s law and theory of sedimentation in formulation and stability
of suspension and emulsion
b2. Select the proper excipients for formulations for solution; suspensions,
emulsions and semisolids.
b3. Predict the stability of various dispersed systems.
b4. Evaluate solutions, suspensions, emulsions and semisolid dosage forms
11 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C3
c1. Design and prepare different liquid dosage forms (solution, suspension,
emulsions) and semisolid dosage forms
c2.
Resolve drug-related problems during formulation of liquid dosage forms
(solution, suspension, emulsions) and semisolid dosage forms
c3. Perform different quality control testing of liquid dosage forms (solution,
suspension, emulsions) and semisolid dosage forms
c4 Perform experiments to differentiate between different type of emulsion
d. General and Transferable Skills:
At the end of this course, student should be able to:
D10 d1. Write a report concerning topics of the course.
d2. Present reports, in the class, related to the course topics.
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction to solution as an oral dosage form. Approaches
to improve drug aqueous solubility 2
2. Non-aqueous solutions, properties of non-aqueous vehicles 2
3. Types of solution, manufacture of solutions and stability 2
4. Pharmaceutical applications of suspensions, Formulation and
stability of suspensions + Quiz 1 2
5. Electrical double layer and Nernst and Zeta potentials and
suspension formulation and stability 2
6. Promotion of flocculation and flocculating agents 2
7. Suspending agents. Problem of using suspending agents and
Formulation additives 2
8. Quiz 2
9. Pharmaceutical application of emulsions, types of emulsion 2
10. Tests for identification of emulsion type. Formulation of
emulsions and formulation additives, Stability of emulsions 2
11. Micro-emulsions 2
12. Creams 2
13. Ointments 2
14. Final Exam
Total:
2 credit hours 15.
12 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Introduction preparation of aromatic water 1
2. Preparation of cough syrup 1
3. Preparation of strong Iodine solution 1
4. Preparation of calamine lotion 1
5. Preparation of suspensions
(black wash and Mist alba suspension) 1
6. Effect of electrolyte onto sedimentation volume of suspension
containing a positive drug 1
7. Emulsion (differentiating between w/o and o/w emulsion ) 1
8. Quiz 2
9. Castor oil emulsion (wet method and Dry Method) 1
10. Olive oil emulsion (Wet method and Dry method) 1
11. Ointment bases (absorption bases) and White field ointment
and (Oleaginous base) Zinc oxide ointment 1
12 Vanishing Cream and Cold Cream 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Class discussions and brain storming
5.3. Laboratories
5.4 LMS
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
13 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (research) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th &15th weeks
Assessment 6 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (research) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1.
Allen, Loyd, and Howard C. Ansel's pharmaceutical dosage forms
and drug delivery systems. Lippincott Williams & Wilkins,
Philadelphia, 2013.
textbook
2.
Aulton, Michael E., and Kevin MG Taylor, eds. Aulton's
Pharmaceutics E-Book: The Design and Manufacture of
Medicines. Elsevier Health Sciences, 2017.
textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures
Study
week Lectures
ILOs
K&U IS P&PS G&TS
1.
Introduction to solution as an oral
dosage form. Approaches to improve
drug aqueous solubility
a1 b2 c1, c2 --
2. Non-aqueous solutions, properties of
non-aqueous vehicles a1, a2 b2 c1, c2 --
3. Types of solution, manufacture of
solutions and stability a1, a2 b4 c1, c2 d1
14 | P a g e
4.
Pharmaceutical applications of
suspensions, formulation and stability
of suspensions
a1, a2, a4 b1, b2,
b3 c1, c2, c3 d2
5.
Electrical double layer and Nernst
and Zeta potentials and suspension
formulation and stability
a2 b2, b3 c1, c2 d1, d2
6. Promotion of flocculation and
flocculating agents a1, a2
b1, b2,
b3, b4 c1, c2, c3 d1, d2
7.
Suspending agents. Problem of using
suspending agents and Formulation
additives
a1, a2, b1, b2,
b3, b4 c1, c2 d1, d2
9. Pharmaceutical application of
emulsions, types of emulsion a1, a2, a3 b1, b2 c1, c2, c4 d1, d2
10.
Tests for identification of emulsion
type. Formulation of emulsions and
formulation additives, Stability of
emulsions
a1, a2, a3,
a4 b3, b4
c1, c2, c3,
c4 d1, d2
11. Micro-emulsions a1, a2, a3 b2, b4 c1, c2 d1, d2
12. Creams a1, a2, a4 b2, b4 c1, c2, C3 d1, d2
13. Ointments a1, a2, a4 b2, b4 c1, c2, C3 d1, d2
8.2. Practical
Study
week Practical
ILOs
K&U IS P&PS G&TS
1. Introduction and preparation of
aromatic water a1 b1 c1 d1, d2
2. Preparation of cough syrup a1, a2 b1, b2 c1, c2 d1, d2
3. Preparation of strong Iodine solution a1, a2 b1, b2 c1, c2 d1, d2
4. Preparation of calamine lotion a1, a2 b1, b2 c1, c2 d1, d2
5. Preparation of suspensions (black wash
and Mist alba suspension) a1, a2 b1, b2 c1, c2 d1, d2
6.
Effect of electrolyte onto sedimentation
volume of suspension containing a
positive drug
a1, a2 b2 c1, c2 d1, d2
7. Emulsion (differentiating between w/o
and o/w emulsion ) a1, a2 b1, b2 c1, c2, c4 d1, d2
9. Castor oil emulsion (wet method and
Dry Method) a1, a2 b2 c1, c2, c4 d1, d2
10. Olive oil emulsion (Wet method and
Dry method) a1, a2 b2 c1, c2, c4 d1, d2
15 | P a g e
11.
Ointment bases (absorption bases) and
White field ointment and (Oleaginous
base) Zinc oxide ointment
a1, a2 b2 c1, c2 d1, d2
12. Vanishing Cream and Cold Cream a1, a2 b2 c1, c2 d1, d2
Name Signature
Course Coordinator: Dr. Osama Amin
Head of Department: Prof. Dr. Ahmed Talat Nouh
Approval Date 29/8/2017
16 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmaceutics-2
Course Code: PH 213
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Fall Semester 2017/2018 Level two
Prerequisite: Pharmaceutics-1 (PH 212)
Credit hours: Lecture: 2 Practical: 1 Total: 3
2. Course Aims:
To provide the students with the basic physicochemical principles in the formulation and
preparation of rectal, vaginal suppositories, aerosols, sterile parenteral and ophthalmic dosage
forms. It also covers the different sterilization methods as well as the quality control of the
finished products.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A2
a1. Define the properties of different types of suppositories, aerosols, sterile
parenteral and ophthalmic dosage forms
a2. Describe and explain the different types of suppositories, aerosols, sterile
parenteral and ophthalmic dosage forms
A6 a3. Understands the principles of sterilization of parenteral and ophthalmic
preparations.
A10 a4. Summarize the advantage and disadvantages of suppositories, aerosols,
sterile parenteral and ophthalmic dosage forms
b. Intellectual Skills:
At the end of this course, student should be able to:
B4
b1.
Design different formulations of suppositories, aerosols, sterile parenteral
and ophthalmic dosage forms
b2. Utilize the basic requirements for preparation of sterile products
b3. Predict the required essential additives for preparation of sterile parenteral
and ophthalmic dosage forms
17 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C3
c1. Design and prepare different dosage forms of rectal and vaginal suppositories
c2. Resolve drug-related problems during formulation of sterile dosage forms,
pharmaceutical aerosol and suppositories.
c3. Perform different quality control testing of sterile dosage forms,
pharmaceutical aerosol and suppositories.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D10 d1. Write a report concerning topics of the course.
d2. Discuss and present reports, in the class, related to the course topics.
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit
Hours
1 Anatomy and physiology of the rectum
Types of Suppository Bases (Fatty Bases, Cocoa Butter) 2
2 Cocoa butter Substitute: Synthetic Bases 2
3 Water miscible bases 2
4 Specific problems in formulating suppositories + (quiz 1) 2
5 Quality control of suppositories 2
6 The advantages and disadvantages parenteral preparations, 2
7 Formulations of parenteral preparations (Components, vehicles and
added substances) 2
8 Quiz 2
9 Containers for parenteral preparations (Glass; Plastics and Rubber
closures; sealing of ampoules. Production facilities and sterilization 2
10 Ophthalmic Preparation (Routes of ocular drug delivery
Factors affecting the bioavailability of topically drugs) 2
11 Formulation and manufacturing of ocular inserts and contact lenses 2
12 Pharmaceutical aerosol (advantages and disadvantages,
components of aerosols. + Types of aerosols) 2
13 Quality control of aerosols package 2
14. Final exams
Total:
2 credit hours 15.
18 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit
Hours
1. Suppository bases (Determination of the displacement value) 1
2. Determination of water number of suppository base 1
3. Cocao butter suppositoires 1
4. Cocao butter suppositoires + Quiz 1 1
5. Glycerogelatin suppositories 1
6. Zinc oxide pessaries 1
7. Soap glycerin suppositories 1
8. Quiz 2
9. Polyethylene glycol suppositories 1
10. Sterile parenteral preparations (Group presentation) 1
11. Ophthalmic preparations Group presentation) 1
12. Pharmaceutical aerosol (Group presentation) 1
13. Practical exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Class discussions (Indirect learning)
5.3. Laboratories
5.4. LMS
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
19 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (research) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th &15th weeks
Assessment 6 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (research) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1.
Allen, Loyd, and Howard C. Ansel. Ansel's pharmaceutical dosage
forms and drug delivery systems. Lippincott Williams & Wilkins,
2013.
textbook
2.
Aulton, Michael E., and Kevin MG Taylor, eds. Aulton's
Pharmaceutics E-Book: The Design and Manufacture of
Medicines. Elsevier Health Sciences, 2017.
textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures and practical:
Study
week Lectures
ILOs
K&U IS P&PS G&TS
1.
Anatomy and physiology of the rectum
Types of Suppository Bases (Fatty Bases,
Cocoa Butter)
a1, a2 b1 c1, c2 --
2. Cocoa butter Substitute: Synthetic Bases a1, a2 b1 c1, c2 --
3. Water miscible bases a1, a2 b1 c1, c2 d1, d2
4. Specific problems in formulating
suppositories + (quiz 1) a1, a2 b1 c1, c2 d1, d2
5. Quality control of suppositories a1, a2,
a4 b1
c1, c2,
c3 d1, d2
21 | P a g e
6. The advantages and disadvantages parenteral
preparations, a1, a2 b1, b2 c1, c2 d1, d2
7. Formulations of parenteral preparations
(Components, vehicles and added substances)
a1, a2,
a3
b1, b2,
b3 c2 d1, d2
9.
Containers for parenteral preparations (Glass;
Plastics and Rubber closures; Sealing of
ampoules, production facilities and
Sterilization
a1, a2,
a3, a4
b1, b2,
b3 c2 d1, d2
10.
Ophthalmic Preparation (Routes of ocular
drug delivery
Factors affecting the bioavailability of
topically drugs)
a1, a2,
a3, a4
b1, b2,
b3 c2 d1, d2
11. Formulation and manufacturing of ocular
inserts and contact lenses
a1, a2,
a3
b1, b2,
b3
c2 d1, d2
12.
Pharmaceutical aerosol (advantages and
disadvantages, components of aerosols. +
Types of aerosols)
a1, a2,
a4 b1 c2, c3 d1, d2
13. Quality control of aerosols package a1, a2,
a4 b1 c2, c3
d1, d2
8.2. Practical
Study
week
Practical
ILOs
K&U IS P&PS G&TS
1. Suppository bases (Determination of the
displacement value) a1, a2 b1 c1, c2 d1, d2
2. Determination of water number of suppository
base a1, a2 b1 c1, c2 d1, d2
3. Cocao butter suppositoires a1, a2 b1 c1, c2,
c3 d1, d2
4. Cocao butter suppositoires a1, a2 b1 c1, c2,
c3 d1, d2
5. Glycerogelatin suppositories a1, a2 b1 c1, c2,
c3 d1, d2
6. Zinc oxide pessaries a1, a2 b1 c1, c2,
c3 d1, d2
7. Soap glycerin suppositories a1, a2 b1 c1, c2,
c3 d1, d2
9. Polyethylene glycol suppositories a1, a2 b1 c1, c2,
c3 d1, d2
21 | P a g e
10. Sterile parenteral preparations
(Group presentation) a1, a2
b1,
b2, b3 c2, c3 d1, d2
11. Ophthalmic preparations
(Group presentation) a1, a2
b1,
b2, b3
c2, c3 d1, d2
12. Pharmaceutical aerosol
(Group presentation) a1, a2 b1, b2 c2, c3 d1, d2
Name Signature
Course Coordinator: Dr. Osama Amin
Head of Department: Prof. Dr. Ahmed Talat Nouh
Approval Date 29/8/2017
22 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Physical pharmacy
Course Code: PH 314
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Fall Semester 2017/2018 Level three
Prerequisite: Physical chemistry (PC 102)
Credit hours: Lecture: 2 Practical: 1 Total: 3
2. Course Aims:
To recognize the physic-chemical properties of drugs (solubility, properties of solutions,
isotonic solutions, viscosity, surface tension and interfacial tensions, adsorption, buffering
systems) and their applications in medicine and pharmacy.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A2 a1. Recognize the importance of physicochemical properties of solid and liquid
drugs
A6
a2. Identify the impact of physicochemical properties of drugs on drugs in their
final dosage forms.
a3. Introduce the basic concepts of the different physicochemical properties and
how they affect the stability and efficacy of the drug.
b. Intellectual Skills:
At the end of this course, student should be able to:
B4
b1. Suggest a suitable method to improve water solubility of different drugs
b2. Utilize the principles of surface phenomena in enhancing solubility of
insoluble drugs
b3. Determine appropriate method for characterization of different surfactants
for proper applications.
B20 b4. Specify a suitable equipment for viscosity measurement
23 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C3
c1. Determine the rheological properties of different dosage forms.
c2. Utilize the surface tension, interfacial tension and critical micelle
concentration.
C13
c3. Assess the solubility of pharmaceutical materials
c4. Prepare isotonic solutions and measure their tonicity.
c5. Select the proper buffer system in pharmaceuticals preparation
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3. d1. Work effectively in a team
D4 d2. Present data to group
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1. Solutions and their properties 2
2.
Solubility and dissolution rate (Solubility, factors affecting
solubility, phase equilibria, phase rule and critical solution
temperature)
2
3. Colligative properties of solutions 2
4. Buffers + Quiz 1 2
5.
Rheology and flow of fluids (rheological behaviour of
different liquids, factors affecting rheology, techniques used
in measuring rheology)
2
6.
Determination of rheological properties of different
pharmaceutical dosage forms. 2
7. Surface and interfacial phenomena 2
8. Quiz 2
9. Measurement of surface and interfacial tensions 2
10.
Surfactants, micellar solubilization and its application in
pharmacy 2
11. Adsorption at solid liquid interface 2
12. Adsorption at liquid-liquid interface 2
13. Application of adsorption 2
14. Final Exam
Total:
2 credit hours 15.
24 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Concentration expression 1
2. Problems on isotonisty 1
3. Buffers 1
4. Buffers problems 1
5. Rheology 1
6. Determination of partition coefficient 1
7. Surface tension 1
8. QUIZ 2
9. Critical micelle concentration 1
10. Hydrophilic lipophilic balance 1
11. Problems on HLB 1
12. Adsorption 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Discussion sessions and problem solving
5.3. Experimental work and laboratories
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
25 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (A written report
about physical properties of a drug) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th &15th weeks
Assessment 6 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (A written report about
physical properties of a drug) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1. Singh, Yashveer. "Martin’s physical pharmacy and pharmaceutical
sciences." Rutgers, The State University of New Jersey (2012). textbook
2.
Aulton, Michael E., and Kevin MG Taylor, eds. Aulton's
Pharmaceutics E-Book: The Design and Manufacture of Medicines.
Elsevier Health Sciences, 2017
textbook
3. Aulton, Michael E., and Diana M. Collet. Pharmaceutical practice.
Churchill Livingstone, 2001. textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Solutions and their properties a1 b3 c2 --
2. Solubility and dissolution rate a1, a2,
a3 b1,b3 c2 --
3. Colligative properties of solutions a1, a2,
a3 b3 c 2 --
4. Buffers a1, a2,
a3 b3 c2 d1, d2
26 | P a g e
5. Rheology and flow of fluids a2, a3 b2 c1 d1, d2
6. Determination of rheological properties of
different pharmaceutical dosage forms. a1, a2 B2 c1 d1, d2
7. Surface and interfacial phenomena a1 ,a3 b1 c1 d1, d2
9.
Measurement of surface and interfacial
tensions a1, a3 b1, b4 c1 d1, d2
10.
Surfactants, micellar solubilization and
its application in pharmacy a1, a2 b1, b4 c5 d1, d2
11. Adsorption at solid liquid interface a1, a2,
a3 b1, b4 c5 d1, d2
12. Adsorption at liquid-liquid interface a1, a3 b1, b4 c3 d1, d2
13. Application of adsorption a1, a3 b1, b4 c3 d1, d2
8.2. Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Concentration expression a1,a2, b3 -- --
2. Problems on isotonisty a1, a3 b3 c4 --
3. Buffers a3 -- c5 --
4. Buffers problems a3 -- c5 d1, d2
5. Rheology a2,a3 b2 c1 d1, d2
6. Determination of partition coefficient a1 b2 c1 d1, d2
7. Surface tension a1,a2 b1 c2 d1, d2
9. Critical micelle concentration a1 b4 c2 d1, d2
10. Hydrophilic lipophilic balance a1,a2 b4 c2 d1, d2
11. Problems on HLB a1,a2 b4 c2 d1, d2
12. Adsorption a2,a3 b4 c2 d1, d2
Name Signature
Course Coordinator: Dr. Osama Amin
Head of Department: Prof. Dr Ahmed Nouh
Approval Date 29.8.2017
27 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Biopharmaceutics and Pharmacokinetics
Course Code: PH 321
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Spring Semester 2017/2018 Level three
Prerequisite: Physical Pharmacy (PH 314)
Credit hours: Lecture: 2 Practical: 1 Total: 3
2. Course Aims:
To provide students with the theoretical basis and basic principles of pharmacokinetics
concerning drug absorption, distribution and elimination in the body. Explore various
parameters affecting bio-availability of drugs to correlate the dosage form of the drug to its
bioavailability.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A8
a1. Define the basics and distinguish the terms biopharmaceutics,
pharmacokinetics and pharmacodynamics.
a2.
Summarize the effects of various physicochemical, biochemical,
physiological and pathological processes on the kinetics and extent of drug
absorption, distribution, and elimination.
A9
a3. Illustrate pharmacokinetic parameters used in clinical pharmacokinetics
using plasma and urine drug level data.
a4. Recognize empirical pharmacokinetic models used to devise and optimize
dosage regimens.
b. Intellectual Skills:
At the end of this course, student should be able to:
B9 b1. Investigate the ways of drug absorption, distribution and elimination of some
selected drugs
B10 b2. Estimate dosage and dosage regimen based on pharmacokinetic principles
b3. Predict time of administration regarding time of eating.
B20 b4. Calculate pharmacokinetic parameters regarding bioavailability and
bioequivalence according to different pharmacokinetic models.
28 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C11
c1. Monitoring patient` medical conditions with his medications based on basic
pharmacokinetics
c2. Determine patient` dose according to his pathological state
c3. Conduct effectively with the patient to find out his problem with the
medication adherence.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work effectively as a part of a team.
D4 d2. Collect and evaluate data in accordance with standard mathematical
methods
D11 d3. Use reasonable solutions for solving problems.
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction to Pharmacokinetics. 2
2. Order of reaction and reaction rate. 2
3. Drug Kinetics Following an Intravenous bolus dose. 2
4. Drug Kinetics following a Single Oral Dose.+ Quiz 1 2
5. Bioavailability and Bioequivalence. 2
6. Steady State Principle and Drug Kinetics during Constant-
Rate Infusion. 2
7. Introduction to Bio-pharmaceutics
Factors affecting drug absorption after oral administration 2
8. Quiz 2
9. Mechanisms of drug absorption and absorption window 2
10. Physiological factors affecting drug absorption
Drug transporters 2
11.
Physicochemical factors affecting drug absorption
Drug dissolution techniques
Dosage form factors affecting drug absorption
2
12. Factors affecting Distribution 2
13. Kinetics of plasma protein binding and its importance 2
14. Final Exam
Total:
2 credit hours 15.
29 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Introduction to bio pharmaceutics and Pharmacokinetics 1
2. Order of elimination kinetics and elimination rate.
First order versus zero order kinetics 1
3. Problems using Cartesian and semi log papers 1
4. Drug Kinetics Following an Intravenous bolus dose 1
5. Drug Kinetics Following an Intravenous bolus dose (Problems
one compartment) 1
6. Drug Kinetics following a Single Oral Dose. 1
7. Introduction to bio pharmaceutics and Pharmacokinetics 1
8. Quiz 2
9. Order of elimination kinetics and elimination rate.
First order versus zero order kinetics 1
10. Problems using Cartesian and semi log papers 1
11. Drug Kinetics Following an Intravenous bolus dose 1
12. Drug Kinetics Following an Intravenous bolus dose (Problems
one compartment) 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Class discussions through brain storming
5.3. Practical classes
5.4. Moodle
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
31 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3
Assignment/activity (A report about
pharmacokinetics of some drugs) each 5
students write one report
all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th &15th weeks
Assessment 6 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (A report about
pharmacokinetics of some drugs) each 5
students write one report (problems)
5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1.
Shargel L, Wu-Pong S, Yu A B C. Applied Biopharmaceutics and
Pharmacokinetics,New York: Appleton & Lange Reviews/McGraw-
Hill. (2005).
Textbook
2. Winter M E. Basic Clinical Pharmacokinetics, 4th ed. Philadelphia:
Lippincott Williams and Wilkins. (2003) Textbook
3. Hedaya, Mohsen A. Basic pharmacokinetics. CRC Press, 2012. Textbook
4.
Ritschel, Wolfgang A., and Gregory L. Kearns. Handbook of basic
pharmacokinetics--including clinical applications. Washington, DC:
American Pharmacists Association, 2004.
Textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction to Pharmacokinetics. a1, a2 b1,b2 c1,c3 -
Order of reaction and reaction rate. a3, a4 b1, b4 c1,c2 -
2. Drug Kinetics Following an
Intravenous a1, a3 b3 c2 d2,d3
31 | P a g e
3. Drug Kinetics following a Single Oral
Dose. a1, a4 b1,b3 c1-c3 d1,d2,d3
4. Bioavailability and Bioequivalence. a1 b1,b2,b3 c1,c2 d2
5. Steady State Principle and Drug
Kinetics during Constant-Rate Infusion. a1 b2,b3 c1,c3 d2,d3
6.
Multiple Dosing and Dosage Regimens.
Metabolite and Urinary Excretion
Kinetics.
Measurement of kidney function
a1,a3,a4 b2,b4 c1 d1,d2
7.
Introduction to Bio-pharmaceutics
Factors affecting drug absorption after
oral administration
a1,a2 b1,b2,b3 c1,c3 d1,d3
9. Mechanism of drug absorption and
absorption window a3 b3 c1,c2 d1,d3
10. Physiological factors affecting drug
absorption. Drug transporters a2 b2 c3 d1,d2,d3
11.
Physicochemical factors affecting drug
absorption
Drug dissolution techniques
Dosage form factors affecting drug
absorption
a1,a2,a3 b1,b4 c3 d2,d3
12. Factors affecting Distribution
a1,a2 b1,b2,b3 c2,c3 d1, d3
13. Kinetics of plasma protein binding and
its importance
8.2. Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction to bio pharmaceutics and
Pharmacokinetics
a1, a2,
a3 b1 c1, c3 --
2.
Order of elimination kinetics and
elimination rate.
First order versus zero order kinetics
a1, a2 b3 c1, c2 --
3. Problems using Cartesian and semi-log
papers a1 b1, b2 c2 d1, d3
4. Drug Kinetics Following an
Intravenous bolus dose a1, a2 b2 c1-c3 d3
5.
Drug Kinetics Following an
Intravenous bolus dose (Problems one
compartment)
a1, a2 b2, b3 c1, c2 d1,d2
6. Drug Kinetics following a Single Oral
Dose. a1, a2 b2, b3 c1, c3 d1, d2
7. Introduction to bio pharmaceutics and
Pharmacokinetics a1, a2 b1 c1 d2,d3
32 | P a g e
9.
Order of elimination kinetics and
elimination rate.
First order versus zero order kinetics
a1, a2 b3, b4 c1, c2 d1,d2,d3
10. Problems using Cartesian and semilog
papers a1 ,a2 b1 c3 d2, d3
11. Drug Kinetics Following an
Intravenous bolus dose a1, a2 b2, b3 c3
d1, d2,
d3
12.
Drug Kinetics Following an
Intravenous bolus dose (Problems one
compartment)
a1, a2 b3, b4 c2, c3 d2, d3
Name Signature
Course Coordinator: Prof. Dr. Mohamed Nasr
Head of Department: Prof. Dr. Ahmed Nouh
Approval Date 10/2/2018
33 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Drug Delivery Systems and Targeting
Course Code: PH 422
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Fall Semester 2017/2018 Level four
Prerequisite: Pharmaceutics-1 (PH 212)
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
To provide students with knowledge about importance of drug delivery systems in improving
therapeutic activity of drugs. Formulation and characterization of sustained, controlled and
targeted release drug delivery systems.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A6
a1. Illustrate the prosperities of active and inactive ingredients on the design of
different dosage forms
a2. Describe the properties of pharmaceutical dosage forms
a3. Identify the different routes of drug administration
a4. Describe the advantages and disadvantages of different drug delivery system
b. Intellectual Skills:
At the end of this course, student should be able to:
B1
b1. Estimate the differences between methods of formulations for various
controlled release preparations
b2. Design of safe and effective drug delivery systems.
b3. Formulate and evaluate controlled and targeted drug delivery system
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C15
c1. Illustrate the basic concepts of controlled drug delivery and targeting
c2. Monitor the methods of development of colloidal carriers for targeting of
drugs
34 | P a g e
d. General and Transferable Skills:
At the end of this course, student should be able to:
D1 d1. Communicate effectively with patients and health care professionals
D3 d2. Work effectively as a part of a team
D4 d3. Collect and present data clearly in oral or written reports
4. Contents:
4.1. Lectures:
4.2. Practical: N/A
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Home works
5.3. LMS
Study
week Topics
No. of
Credit Hours
1. Controlled and modulated release drug delivery systems
(definition, advantages, disadvantages, theory, methods) 2
2. Colloidal drug delivery systems (Liposomes) 2
3. Therapeutic applications of liposomes. 2
4. Advantages of proliposomes as a controlled release drug
delivery systems + Quiz 1 2
5. Colloidal drug delivery systems (Niosomes) 2
6. Therapeutic applications of niosomes. 2
7. Advantages of niosomes as controlled drug delivery systems. 2
8. Quiz 2
9. Different controlled release drug delivery systems. 2
10. Nanoparticles as controlled drug delivery systems. 2
11. Microemulsions. 2
12.
Controlled drug delivery systems" coated beads,
microencapsulation, complex formation, resonated
drugs,.etc"
2
13. Microspheres and microcapsules.
Different types of microspheres. 2
14. Final Exam
Total:
2 credit hours 15.
35 | P a g e
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
3. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
4. Quizzes To assess knowledge, understanding and intellectual skills.
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (Scientific reports) all over the term
Assessment 4 Oral exam 14th &15th weeks
Assessment 5 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (Scientific reports) 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
7. List of References:
No. Reference Type
1. Wilson, Clive G., and Patrick J. Crowley, eds. Controlled release in
oral drug delivery. Springer Science & Business Media, 2011. textbook
2. Li, Xiaoling. Design of controlled release drug delivery systems.
McGraw Hill Professional, 2005. textbook
3.
Rathbone, Michael J., Jonathan Hadgraft, Michael S. Roberts, and
Majella E. Lane. Modified-release drug delivery technology. CRC
Press, 2008.
textbook
4.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951594/
https://www.sciencedirect.com/book/9780444820273/advances-in-
drug-delivery-systems-6
Periodicals and
website
36 | P a g e
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Controlled and modulated release drug
delivery systems (definition,
advantages, disadvantages, theory,
methods)
a1, a2,
a3 b1 c1 --
2. Colloidal drug delivery systems(
Liposomes )
a1, a2,
a4 b2 c1-c2 --
3. Therapeutic applications of liposomes. a1, a2,
a4 b3 c2 d3
4.
Advantages of proliposomes as a
controlled release drug delivery
systems.
a4 b1, b3 c1,c2 d1-d3
5. Colloidal drug delivery systems
(Niosomes ) a1,a2 b1, b3 c2 d2
6.
Therapeutic applications of niosomes.
Advantages of proniosomes as
controlled drug delivery systems.
a2 b1, b2,
b3 c1 d3
7. Advantages of niosomes as controlled
drug delivery systems. a1 b1 c1, c2 d1
9. Different controlled release drug
delivery systems. a2, a3 c1, c2 d1-d3
10. Nanoparticles as controlled drug
delivery systems. a1 b1 c1 ,c2 d1
11. Micro-emulsions. a2 b1 c1, c2 d1, d2
12.
Controlled drug delivery systems"
coated beads, microencapsulation,
complex formation, resonated
drugs,.etc"
a2 b1 c1,c2 d1-d3
13. Microspheres and microcapsule-
Different types of microspheres. a1, a2 b1 c1,c2 d2
Name Signature
Course Coordinator: Dr: Yasser Abdelalim
Head of Department: Prof. Dr. Ahmed Talat Nouh
Approval Date 29/8/2017
37 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmaceutical Technology-1
Course Code: PH 431
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Spring Semester 2017/2018 Level four
Prerequisite: None
Credit hours: Lecture:2 Practical:1 Total:3
2. Course Aims:
To provides the students with the basic principles, concepts, and theories of various unit
operations related to pharmaceutical technology and energy consumption. The course covers
most of the equipment utilized in heat transfer, evaporation, drying and crystallization to
achieve the maximum outcomes and proper manufacturing. The course also covers how to
select the most suitable equipment for manufacturing certain drugs.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A7
a1. Describe the theory behind different pharmaceutical operations
(Crystallization, Drying, evaporation and heat transfer).
a2. Acquire knowledge about different types of machinery used for different unit
operation.
a3. Enumerate factors affecting the different operation process.
a4. Define different industrial operations involved in the production of
pharmaceutical products.
b. Intellectual Skills:
At the end of this course, student should be able to:
B2
b1. Interpret the concept and theory of different unit operations for
Crystallization, Drying, evaporation and heat transfer
b2. Select the most suitable equipment for certain operations.
b3. Design the appropriate protocol for manufacturing different dosage forms
b4. Integrate the equipment to improve the performance of certain operation.
38 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C4 c1. Utilize the studied equipment for different unit operations.
C8 c2.
Analyze and perform experiment for certain unit operations to find out the
proper technique for pharmaceutically accepted production.
c3. Analyze the results obtained from each unit operation.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work in team
D4 d2. Present data to group
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1. Introduction and definitions.
Layouts for manufacture of pharmaceutical products. 2
2. Heat Transfer (Concept and Heat transfer equipment) 2
3. Single pass heater and Multiple pass heater
Liquid-Liquid Heat Exchanger 2
4. Evaporation + Quiz 1
(Concept and applications) 2
5. Evaporation (Forced Circulation and Film evaporators) 2
6. Evaporation Accessories 2
7. Drying (Concept and Equilibrium Moisture Contents)
Drying behavior for materials 2
8. Quiz 2
9 Equipment for solid and liquid drying 2
10 Crystallization (Fundamentals and Theories) 2
11. Factors affecting crystallization process, - Fractional
Crystallization 2
12 Equipment (Cooler Crystallizers and evaporative crystallizers 2
13 Vacuum Crystallizers 2
14. Final Exam
Total:
2 credit hours 15.
39 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Fundamentals to pharmaceutical technology 1
2. Heat transfer problems 1
3. Heat transfer problems 1
4. Heat transfer problems 1
5. Evaporation problems 1
6. Evaporation problems 1
7. Drying problems 1
8. Quiz 2
9. Evaluation of capsules 1
10. Evaluation of capsules 1
11. Evaluation of tablets 1
12. Evaluation of tablets 1
13. Practical exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Class discussion
5.3. Equipment simulation
5.4. Laboratories
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general &
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
41 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (Drawing sketches) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th &15th weeks
Assessment 6 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (Drawing sketches) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1. Essential books (text books):
Lachman, Leon, Herbert A. Lieberman, and Joseph L. Kanig. The
theory and practice of industrial pharmacy. Philadelphia: Lea &
Febiger, 2015.
Broadhead, Joanne, and Mark Gibson. "Parenteral dosage forms."
Pharmaceutical Preformulation and Formulation: A Practical
Guide from Candidate Drug Selection to Commercial Dosage
Form (2001): 331-354.
Textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Lectures
ILOs
K&U IS P&PS G&TS
1.
Introduction and definitions.
Layouts for manufacture of pharmaceutical
products.
a1 b1 , b2 c1, --
2. Heat Transfer (Concept and Heat transfer
equipment) a2 b1 , b2 c1, c2 ---
3. Single pass heater and Multiple pass heater
Liquid-Liquid Heat Exchanger a2 b1 , b2 c1 d2
4. Evaporation
(Concept and applications) a1 , a2 b1 , b2 c1, c3 d2
41 | P a g e
5. Evaporation (Forced Circulation and Film
evaporators) a1 , a2 b1, b4 c1, c3 d2
6. Evaporation accessories a2 b1, b4 c2, c3 d2
7.
Drying (Concept and Equilibrium Moisture
Contents)
Drying behavior for materials
a2 b1, b2 c1-c3 d1, d2
9. Equipment for solid and liquid drying a1 , a2 b1, b2 c1 d1, d2
10. Crystallization (Fundamentals and Theories) a1 , a2 b1, b2 c1, c2 d1, d2
11. Factors affecting crystallization process, -
Fractional Crystallization a3 , a4 b1, b2 c2, c3 d1, d2
12. Equipment (Cooler Crystallizers and evaporative
crystallizers)- a3 , a4 b1, b3 c2,c3 d1, d2
13. Vacuum Crystallizers a1 , a2 b1, b3 c2,c3 d1, d2
8.2. Practical
Study
week Practical
ILOs
K&U IS P&PS G&TS
1. Fundamentals to pharmaceutical technology part a1 b1, b2 c1, c2 --
2. Heat transfer problems a2 b1, b2 c1, c2 --
3. Heat transfer problems a2 b1, b2 c1, c3 --
4. Heat transfer problems a1, a2 b1, b2 c1, c3 d1 , d2
5. Evaporation problems a1, a2 b1, b4 c1, c3 d1 , d2
6. Evaporation problems a2 b1, b4 c1, c3 d1 , d2
7. Drying problems a2 b1, b2 c1, c2,
c3 d1 , d2
9. Evaluation of capsules a1, a2 b1, b2 c1 d1 , d2
10. Evaluation of capsules a1, a2 b1, b2 c1, c2 d1 , d2
11. Evaluation of Tablets a3, a4 b3, b4 c2, c3 d1 , d2
12. Evaluation of Tablets a3, a4 b3, b4 c3 d1 , d2
Name Signature
Course Coordinator: Prof. Dr. Ahmed Nouh
Head of Department: Prof. Dr. Ahmed Nouh
Approval Date 10/2/2018
42 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Pharmaceutical Technology-2
Course Code: PH 532
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Fall Semester 2017/2018 Level five
Prerequisite: Pharmaceutical Technology-1 (PH 431)
Credit hours: Lecture:2 Practical:1 Total:3
2. Course Aims:
The course provides the students with the basic principles, concepts and equipment of
various unit operations related to particle size reduction, particle size enlargement, solid
mixing, liquid mixing, semisolid mixing, filtration and centrifugation to achieve the
maximum outcomes and proper manufacturing.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A7
a1.
Describe the theory behind different pharmaceutical operations (particle size
reduction, particle size enlargement, solid mixing, liquid mixing, semisolid
mixing, filtration and centrifugation).
a2.
Acquire knowledge about different types of machinery used for particle size
reduction, particle size enlargement, solid mixing, liquid mixing, semisolid
mixing, filtration and centrifugation
a3. Enumerate factors affecting the different operation process.
a4. Describe the importance of each part of the instrument stressing on its
significance and the way of improving its function.
b. Intellectual Skills:
At the end of this course, student should be able to:
B2
b1.
Interpret the concept and theory of different unit operations for particle size
reduction, particle size enlargement, solid mixing, liquid mixing, semisolid
mixing, filtration and centrifugation
b2.
Select the most suitable equipment for particle size reduction, particle size
enlargement, solid mixing, liquid mixing, semisolid mixing, filtration and
centrifugation
b3. Design the appropriate protocol for manufacturing different dosage forms
43 | P a g e
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C4 c1. Recognize the studied equipment for different unit operations.
C8 c2.
Analyze and perform experiments for certain unit operations to find out the
proper technique for pharmaceutically accepted production.
c3. Manage the different instruments of each unit operation.
d. General and Transferable Skills:
At the end of this course, student should be able to:
D3 d1. Work in team
D4 d2. Present data to group
4. Contents:
4.1. Lectures:
Study
week Topics
No. of
Credit Hours
1.
Particle size reduction
Objectives of size reduction
Influence of material products on size reduction
Influence of size reduction on size distribution
Size reduction methods
2
2.
Compression between different methods (Roller mill)
Attrition methods (Roller mill)
Combined Attrition and Impaction methods (Pin mill & Fluid
energy mill)
Colloid mill
Selection of particle size reduction methods
2
3. Theory, concept, reasons and importance of size enlargement 2
4. Equipment for dry and wet granulation + QUIZ 1 2
5. Size separation, importance and equipment 2
6. Theory, concept and importance of mixing
Mixing of liquids (Equipment) 2
7. Mixing of solids and semisolids (Equipment) 2
8. Quiz 2
9. Theory, concept and importance of filtration 2
10. Equipment of filtration 2
11. Theory, concept and importance of centrifugation 2
12. equipment of centrifugation 4
13.
14. Final Exam
Total:
2 credit hours 15.
44 | P a g e
4.2. Practical:
Study
week Topics
No. of
Credit Hours
1. Size reduction theories 1
2. Size reduction by impaction 1
3. Size reduction by compression 1
4. Size reduction by attrition 1
5. Size reduction by impaction and attrition 1
6. Equipment reducing coarse particles 1
7. Equipment reducing intermediate particles 1
8. Quiz 2
9. Equipment reducing fine particles 1
10. Equipment for mixing of solid 1
11. Equipment for mixing of semisolid 1
12. Equipment for pelletizer 1
13. Practical Exam 1
14. Final Exam
Total:
1 credit hour 15.
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Class discussion
5.4. Laboratories
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Practical exam To assess professional and practical skills.
3. Course work To assess knowledge, understanding, intellectual skills, general&
transferable skills.
4. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
5. Quizzes To assess knowledge, understanding and intellectual skills.
45 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (Sketch book) all over the term
Assessment 4 Practical exam 13th week
Assessment 5 Oral exam 14th &15th weeks
Assessment 6 Written exam 14th &15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (sketch book) 5
2. Final-Term Exam 40
3. Oral Exam 10
4. Practical Exam 25
Total 100%
7. List of References:
No. Reference Type
1.
Essential books (text books):
Lachman, Leon, Herbert A. Lieberman, and Joseph L. Kanig. The theory and
practice of industrial pharmacy. Philadelphia: Lea & Febiger, 2013.
Broadhead, Joanne, and Mark Gibson. "Parenteral dosage forms." Pharmaceutical
Preformulation and Formulation: A Practical Guide from Candidate Drug
Selection to Commercial Dosage Form (2001).
textbook
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1.
Particle size reduction
Objectives of size reduction
Influence of material products on size
reduction
Influence of size reduction on size
distribution
Size reduction methods
a1 b1 , b2 c1 , c2 --
46 | P a g e
2.
Compression between different methods
(Roller mill)
Attrition methods (Roller mill)
Combined Attrition and Impaction methods
(Pin mill & Fluid energy mill)
Colloid mill
Selection of particle size reduction methods
a1, a2 b1, b2,
b3 -- --
3. Theory, concept, reasons and importance of
size enlargement a1, a2 b1, b2 c1, c3 d2
4. Equipment for dry and wet granulation a1, a2 b1, b2,
b3 c1, c3 d2
5. Size separation, importance and equipment a1, a2 b1 c1, c3 d2
6. Theory, concept and importance of mixing
Mixing of liquids (Equipment) a1, a3 b1, b3 c1 , c3 d2
7. Mixing of solids and semisolids
(Equipment) a1, a2
b1,
b2,b3
c1, c2,
c3 d1 , d2
9. Theory, concept and importance of filtration a1, a2 b1, b2 c1, c2,
c3 d1 , d2
10. Equipment of filtration a2 b2,b3 c1 d1 , d2
11. Theory, concept and importance of
centrifugation
a1, a2,
a3, a4 b1 , b3 c3 d1 , d2
12. Equipment of centrifugation a2, a3, a4 b1 , b3 c3 d1 , d2
13.
8.2. Practical:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Size reduction theories a1 , a2 b1 , b2 c1 --
2. Size reduction by impaction a1 , a2 b1 , b2 c1 --
3. Size reduction by compression a1 , a2 b1 , b2 c1 d1
4. Size reduction by attrition a1 , a2 b1 , b2 c1, c3 d1, d2
5. Size reduction by impaction and
attrition a1 , a2 b1 , b2 c1 d2
6. Equipment reducing coarse particles a1 , a2 b1 , b2 c1, c3 d1, d2
47 | P a g e
7. Equipment reducing intermediate
particles a1 , a2 b2 , b3
c1, c2,
c3 d1, d2
9. Equipment reducing fine particles a1 , a2 , b2, b3 c2, c3 d1, d2
10. Equipment for mixing of solid a3 , a4 b2, b3 c3 d1, d2
11. Equipment for mixing of semisolid a3 , a4 b2, b3 c3 d1, d2
12. Equipment for pelletizer a3 , a4 b2, b3 c3 d1, d2
Name Signature
Course Coordinator: Prof. Dr. Ahmed Nouh
Head of Department: Prof. Dr. Ahmed Nouh
Approval Date 29/8/2017
48 | P a g e
Delta University for Science and Technology
Quality Assurance Center
Course Specifications
1. Basic Information:
Course Title: Radiopharmaceutics
Course Code: PH 521
Program on which the course is given: B. Pharm.
Department offering the course: Pharmaceutics
Academic year/ level: Spring Semester 2017/2018 Level five
Prerequisite: None
Credit hours: Lecture: 2 Practical: 0 Total: 2
2. Course Aims:
Providing students with fundamentals, uses and danger of radiopharmaceuticals. In addition,
increasing the skills required for pharmacists to deal with radiopharmaceuticals dosage form.
Preparation and characterization of radiopharmaceuticals used in treatment and diagnosis of
some diseases.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding:
At the end of this course, student should be able to:
A2
a1. Identify the radioisotopes and radiopharmaceuticals
a2. Define the characteristics of ideal isotopes in medical field and how they
are produced
A6 a3. Describe the different aseptic manufacturing processes for
radiopharmaceuticals.
b. Intellectual Skills:
At the end of this course, student should be able to:
B1 b1. Design and plan for quality control in Nuclear Medicine Department.
B4 b2. Formulate guidelines for nuclear pharmacy practice.
B20 b3. Evaluate guidelines for proper sewage disposal in a nuclear facilaties
c. Professional and Practical Skills:
At the end of this course, student should be able to:
C2 c1. Validate and conduct quality control tests of sterile dosage forms.
c2. Perform experiments to differentiate between different types preparations.
C13 c3. Utilize different methods for preparation of sterile radiopharmaceuticals
49 | P a g e
d. General and Transferable Skills:
At the end of this course, student should be able to:
D10 d1. Write a report concerning topics of the course
d2. Discuss and present reports in the class related to the course topics.
4. Contents:
4.1. Lectures:
4.2. Practical: N/A
5. Teaching and Learning Methods:
5.1. Lectures
5.2. Class discussion and brain storming
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam To assess knowledge, understanding, intellectual and professional
skills.
2. Course work To assess knowledge, understanding, intellectual skills, general &
transferable skills.
3. Oral exam To assess knowledge, understanding, intellectual skills, general skills
and confidence.
4. Quizzes To assess knowledge, understanding and intellectual skills.
Study
week Topics
No. of
Credit Hours
1. Introduction to atom and radioisotopes 2
2. Factors affecting formulation of radiopharmaceuticals 2
3. Production of and types of official radiopharmaceuticals 2
4. Types of radioactivity + Quiz 1 2
5. Radioactive decay 2
6. Generators for radiopharmaceuticals 2
7. Pharmaceutical uses of generators 2
8. Quiz 2
9. Quality control of radiopharmaceuticals 2
10. Applications of radiopharmaceutical in treatments 2
11. Applications of radiopharmaceutical in diagnosis 2
12. Official examples of radiopharmaceuticals for treatments 2
13. Official examples of radiopharmaceuticals for diagnosis 2
14. Final Exam
Total:
2 credit hours 15.
51 | P a g e
6.2. Assessment schedule:
Assessment 1 Quiz 1 4th week
Assessment 2 Quiz 2 8th week
Assessment 3 Assignment/activity (Written reports
prepared groups of students) all over the term
Assessment 4 Oral exam 14th & 15th weeks
Assessment 5 Written exam 14th & 15th weeks
6.3. Weighing of Assessments:
1. Course work:
- Quiz 1 10
- Quiz 2 10
- Assignment/activity (Written reports prepared
groups of students) 5
2. Final-Term Exam 65
3. Oral Exam 10
Total 100%
7. List of References:
No. Reference Type
1.
Taylor, Andrew, David M. Schuster, and Naomi P. Alazraki. A
clinician's guide to nuclear medicine. Society of Nuclear Medicine,
Incorporated, 2006.
textbook
2.
Allen, Loyd, and Howard C. Ansel. Ansel's pharmaceutical dosage
forms and drug delivery systems. Lippincott Williams & Wilkins,
2013.
textbook
3.
Joseph, Usha A. "A Clinician's Guide to Nuclear Oncology: Practical
Molecular Imaging and Radionuclide Therapies." The Journal of
Nuclear Medicine 51, no. 3 (2010): 492.
Periodical
8. Matrix of course contents versus ILOs:
8.1. Lectures:
Study
week Course Contents
ILOs
K&U IS P&PS G&TS
1. Introduction to atom and radioisotopes a1, a2 b1 c1 --
2. Factors affecting formulation of
radiopharmaceuticals a3 b2 c2 --
3. Production of and types of official
radiopharmaceuticals a1, a2 b1 c2 d1
4. Types of radioactivity a3 b3 c3 d1
51 | P a g e
5. Radioactive decay a1 b3 c3 d1
6. Generators for radiopharmaceuticals a2 b2 c1, c3 --
7. Pharmaceutical uses of generators a2 b2 c3 d1
9. Quality control of radiopharmaceuticals a1, a2 b2 c3 d2
10. Applications of radiopharmaceutical in
treatments a2,a3 b2 c3 d2
11. Applications of radiopharmaceutical in
diagnosis a2,a3 b2 c3 d2
12. Official examples of
radiopharmaceuticals for treatments a2, a3 b2 c3 d2
13. Official examples of
radiopharmaceuticals for diagnosis a2,a3 b2 c3 d2
Name Signature
Course Coordinator: Dr. Osama Amin
Head of Department: Prof. Dr. Ahmed Nouh
Approval Date 10-2-2018
52 | P a g e
Other Courses Not Opened for Registration
at Academic Year (2017-2018)
Final Approval 2016-2017
53 | P a g e
1. Basic Information:
Course title: Fundamentals of Cosmetology
Course code: PH 415
Program on which the course is given: B. Pharm.
Department: Pharmaceutics
Academic level: Faculty Elective
Prerequisite: None
Credit hours: Lecture: 2 Practical: - Total: 2
2. Course aims:
Define different cosmetic preparations, mention ideal characters of different active and
inactive excipients used in cosmetic preparations, describe the ideal properties of different
dosage forms as cleansing creams, cold, vanish and foundation creams, hair preparations,
cosmetic posers, nail lacquers and polishers, dental pastes…. Etc., and demonstrate different
methods for preparation of cosmetic preparations.
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding: At the end of this course, student should be able to:
A6
a1 Describe preparations properties and Mention Ideal characters of each
cosmetic preparations.
a2 Describe the ideal properties of excipients used in cosmetics.
a3 Mention the advantages and disadvantages of cosmetic preparations.
A17 a4 Describe the procedures used for the preparation of cosmetics.
b. Intellectual Skills: At the end of this course, student should be able to:
B1
b1 Compare between different methods of formulations for different cosmetic
preparations
b2 Design appropriate formulations for cleansing creams; lipsticks, toilet powder,
shampoos, tooth pastes and depilatories.
c. Professional and Practical Skills: At the end of this course, student should be able to:
C3 c1 Utilize appropriate excipient properties to enhance cosmetic formulation.
C11 c2 Utilize appropriate information to differentiate between cosmetic preparations.
d. General and Transferable Skills: At the end of this course, student should be able to:
D3 d1 Work efficiently as a part of a team
D4 d2 Collect, evaluate and present data I accordance with standard mathematical
and statistical methods
54 | P a g e
4. Contents
4.1. Lectures
No. of
week Topic No. of credit hours
1 Cosmetic preparations (definition and overview) 2
2 Cleansing creams (Definition, types, and Application) 2
3 Cold and Vanishing cream 2
4 Foundation cream 2
5 Toilet powders “cosmetic Posers”
Quiz 2
6 Deodorants 2
7 Midterm Exam ---
8 Shampoos, and Shaving preparations 2
9 After shave preparation 2
10 Lipstick 2
11 Nail lacquers 2
12 Hair removers (Depilatories and Depilatories) Dental
pastes 2
13 Practical exam 2
14 Final exam 2 credit hours
15
4.2. Practical/Tutorial: N/A
5. Teaching and Learning Methods:
5.1 Lectures
5.2 Class discussions.
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional skills
2. Quizzes to assess knowledge, understanding and intellectual skills
6.2. Assessment schedule:
Assessment 1 Mid-term 7th week
Assessment 2 Quiz 5th week
Assessment 3 Written 14th &15th weeks
55 | P a g e
6.3. Weighing of Assessments:
Mid-Term Exam & course work 25
Final-Term Exam 75
Total 100%
7. List of References:
No. Reference type
1.
H.C. Ansel; Pharmaceutical Dosage Forms and drug
Delivery Systems’ Lea & Febiger; Philadelphia; London
(Latest Edition)
Textbook
2. Milady S Standard Textbook of Cosmetology
by Milady Publishing Company
Textbook
8. Matrix of learning and skills:
Study
week Course contents
ILOs
knowledge
and
understanding
intellectual
skills
professional
and
practical
skills
general and
transferable
skills
1 Cosmetic preparations (definition and overview)
a1-a2 b1 c1, c2 d1- d2
2 Cleansing creams (Definition, types, and Application)
a1-a4 b1, b2 c1, c2 d1- d2
3 Cold and Vanishing cream a1 b1 c1, c2 d1- d2
4 Foundation cream a1-a3 b1 c1, c2 d1- d2
5 Toilet powders “cosmetic Posers” Quiz
a1-a4 b1, b2 c1, c2 d1- d2
6 Deodorants a1-a4 b1 – b2 c1 , c2 d1- d2
8 Shampoos, and Shaving preparations
a1-a4 b1 – b2 c1 , c2 d1- d2
9 After shave preparation a1-a4 b1 – b2 c1 , c2 d1- d2
10 Lipstick a1-a2 b1 – b2 c1 , c2 d1- d2
11 Nail lacquers a1-a3 b1 c1 , c2 d1- d2
12 Hair removers (Depilatories and Depilatories)
a1-a2 b1 – b2 c1 , c2 d1- d2
13 Dental pastes a1-a4 b1 – b2 c1 , c2 d1- d2
Name Signature
Course Coordinator: Dr. Osama Amin Mahmoud
Head of Department: Dr. Ahmed Talat Ibrahim Nouh
Approval Date 11/2/2017
56 | P a g e
1. Basic Information:
Course title: Dosage form design Course code: PH 522
Program on which the course is given: B. Pharm.
Department: Pharmaceutics
Academic level: Faculty Elective
Prerequisite: None
Credit hours: Lecture: 2 Practical:- Total: 2
2. Course Objectives:
Providing students by reasons for the incorporation of drugs into various dosage forms.
Compare and contrast the properties of various drug dosage forms. Categorize various
pharmaceutical ingredients and excipients. Providing students with the information needed in
pre-formulation studies to characterize a drug substance for possible inclusion into a dosage
form. Summarize approaches employed to stabilize drugs in pharmaceutical dosage forms
3. Intended Learning Outcomes (ILOs):
a. Knowledge and understanding: At the end of this course, student should be able to:
A6 a1 Describe the properties of different types of pharmaceutical dosage forms
A8
a2 Define the basics and distinguish the terms biopharmaceutics, pharmacokinetics
and pharmacodynamics.
a3
Summarize the effects of various physicochemical, biochemical, physiological
and pathological processes on the kinetics and extent of drug absorption,
distribution, and elimination.
b. Intellectual Skills: At the end of this course, student should be able to:
B9 b1 Investigate the ways of drug absorption, distribution and elimination of some
selected drugs
B10 b2 Estimate dosage and dosage regimen based on pharmacokinetic principles
c. Professional and Practical Skills: At the end of this course, student should be able to:
C3
c1 Utilize appropriate laboratory techniques in preparing different types of
pharmaceutical dosage forms
c2 Perform experiments to enhance liquid stability
C11 c3 Monitoring patient` medical conditions with his medications based on basic
pharmacokinetics
d. General and Transferable Skills: At the end of this course, student should be able to:
D1 d1. Develop a rational thinking in formulation and production of different types
of pharmaceutical dosage forms
D4 d2. Collect and evaluate data in accordance with standard mathematical methods
D11 d3. Use reasonable solutions for solving problems based on phamakokinetic data.
57 | P a g e
4. Contents 4.1. Lectures
Week
No. Topic No. of credit hours
1 THE NEED FOR DOSAGE FORMS 2
2 GENERAL CONSIDERATIONSIN DOSAGE
FORM DESIGN 2
3 PREFORMULATION STUDIES 2
4 Drug Stability: Mechanismsof Degradation 2
5 Drug and Drug Product Stability:Kinetics and Shelf
Life 2
6 Q10 Method of Shelf Life Estimation 2
7 Midterm Exam --
8 Enhancing Stability of Drug Products 2
9 Standard Curves 2
10 PHARMACEUTICAL INGREDIENTSAND
EXCIPIENTS 2
11 Flavoring Pharmaceuticals 2
12 Sweetening Pharmaceuticals 2
13 Coloring Pharmaceuticals 2
14 Final exam 2 credit hours
15 Final exam
4.2. Practical/Tutorial: N/A
5. Teaching and Learning Methods:
5.1 Lectures
5.2 Class discussions
6. Student Assessment Methods:
6.1. Assessment methods:
1. Written exam to assess knowledge, understanding, intellectual and professional skills
2. Quizzes to assess knowledge, understanding and intellectual skills
6.2. Assessment schedule:
Assessment 1 Quiz 5th week
Assessment 2 Mid-term 7th week
Assessment 3 Written 14th &15th weeks
58 | P a g e
6.3. Weighing of Assessments:
Mid-Term Exam & course work 25
Final-Term Exam 75
Total 100%
7. List of References:
No. Reference type
1. FDA/ICH Regulatory Guidance on Stability. In: Federal Register, vol 63,
Washington: Food & Drug Administration, 1998:9795–9843. Textbook
2. Sheinin EB. ICH Guidelines: History, Present Status, Intent. Athens, GA:
International Good Manufacturing Practices Conference, 1998.
Textbook
8. Matrix of learning and skills:
Study
week Course contents
ILOs
knowledge
and
understanding
intellectual
skills
professional
and
practical
skills
general and
transferable
skills
1 THE NEED FOR DOSAGE FORMS a1-a3 b1,b2 c1-c3 d1-d3
2 GENERAL CONSIDERATIONSIN
DOSAGE FORM DESIGN a1-a3 b1,b2 c1-c3 d1-d3
3 PREFORMULATION STUDIES a1-a3 b1,b2 c1-c3 d1-d3
4 Drug Stability: Mechanismsof
Degradation a1-a3 b1,b2 c1-c3 d1-d3
5
Drug and Drug Product
Stability:Kinetics and Shelf Life a1-a3 b1,b2 c1-c3 d1-d3
6 Q10 Method of Shelf Life Estimation a1-a3 b1,b2 c1-c3 d1-d3
8 Enhancing Stability of Drug Products a1-a3 b1,b2 c1-c3 d1-d3
9 Standard Curves a1-a3 b1,b2 c1-c3 d1-d3
10 PHARMACEUTICAL
INGREDIENTSAND EXCIPIENTS a1-a3 b1,b2 c1-c3 d1-d3
11 Flavoring Pharmaceuticals a1-a3 b1,b2 c1-c3 d1-d3
12 Sweetening Pharmaceuticals a1-a3 b1,b2 c1-c3 d1-d3
13 Coloring Pharmaceuticals a1-a3 b1,b2 c1-c3 d1-d3
Name Signature
Course Coordinator: Dr. Rashad Kaoud
Head of Department: Dr. Ahmed Talat Ibrahim Nouh
Approval Date 11/2/2017