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    RINGDOC January 1989 - December 1991 5 of 23

    AN: 91-51472LA: E-EnglishPN: 33 35 46 64AU: Svendsen-U-G; Jorgensen-HJN: Eur.Resp.J. (4, No. 8, 992-99, 1991)TI: Inhaled Nedocromil Sodium as Additional Treatment to High Dose InhaledCorticosteroids in the Management of Bronchial Asthma.AB: A double-blind, randomized, placebo controlled study favored inhalednedocromil Na (NC) over placebo for improvement of symptoms and pulmonaryfunction in 35 bronchial asthmatics using high dose inhaled beclometasonedipropionate or budesonide and inhaled bronchodilators with or withouttheophylline tablets. Additional NC treatment was superior to placebo forreduction in daytime symptoms, increase in morning peak expiratory flow (PEF)and clinical opinion. Side-effects of NC included bitter/bad taste, dizziness,vomiting.

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    AN: 91-50959TG: G

    LA: E-EnglishPN: 29 69AU: Magenheim-B; Benita-SLO: Jerusalem, Isr.CO: 8645MJN: STP-Pharm.Sci. (1, No. 4, 221-41, 1991)TI: Nanoparticle Characterization: A Comprehensive Physicochemical Approach.AB: Nanoparticles (NP) are reviewed with regard to size, surface morphology, charge, polymer molecular weight (MW), turbidity, drug content and release, biodegradation, sterility/apyrogenicity and stability. Incorporated drugs include amikacin, amphotericEX: Scanning electron microscopy (SEM) has been used to study NP size, morphology, surface roughness and porosity, but surfactants can hinder SEM observation of

    NP. The effects of manufacturing parameters on NP size and morphology have been studies usingDepartment of Pharmacy, School of Pharmacy, The Hebrew University of Jerusalem,P.O. Box. 12065, Jerusalem 91120, Israel.PY: 1991AY: 91UD: 9112LT: LT-*01* MAIN-TOPIC; NANOCAPSULE; FORMULATION; QUALITY-CONTROL; PHARM.PREP.;PHARMACEUTICS; OCLT-*02* AMIKACIN-OC; AMPHOTERICIN-B-OC; GENTAMYCIN-OC; INDOMETACIN-OC; AMPICILLIN-OC; PRIMAQUINE-OC; DOXORUBICIN-OC; METRONIDAZOLE-OC; PROPIDIUM-OC; DEXAMETHASONE-OC; ROSE-BENGAL-OC; ADENINE-OC; METHOTREXATE-OC; INSULIN-OC; PILOCARPINE-OC;VIDARABINE-OC; H

    TI: Identification of antimicrobial gingerols from ginger (Zingiber officinaleRoscoe)AU: Yamada-Y; Kikuzaki-H;Nakatani-NAD: Department of Food Science, Doshisha Women's Coll. Liberal Arts,Teramachi-Imadegawa, Kamikyo-ku, Kyoto, JapanSO: J-ANTIBACTERIAL-ANTIFUNGAL-AGENTS-JPN. 20/6 (309-311) 1992CO: BOBODISSN: 0385-5201

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    PY: 1992CP: JapanLA: EnglishLS: EnglishDE: *antimicrobial-activity; bacillus-subtilis;high-preformance-liquid-chromatography; escherichia-coli; drug-isolation;drug-identification; spectroscopy-; nonhuman-; article-; *plant-extract;*ginger-; *8-gingerol-pharmacology; 8-gingerol-drug-analysis;*8-gingerol-drug-development; *10-gingerol-pharmacology;*10-gingerol-drug-analysis; *10-gingerol-drug-developmentRN: 68038-70-0; 68583-22-2EM: bacterium- (762); nonhuman- (777); article- (60);higher-plant (697);plant- (699)TG: 762; 777; 60; 697; 699PT: J (Journal-Article)AN: 92221810