Did sex with Neanderthals and

Denisovans shape our immune system?

A12Erin McCaskey

Mackenzie WilliamsPeyton AiringtonArturo Salmeron

Dongeun Kim

Our Immune Systems Resulted from Multiregional Admixture

Pinna 2011

Abi-Rached et al. 2011

Abi-Rached et al. 2011

Abi-Rached et al. 2011

Abi-Rached et al. 2011

Discussion & Conclusion

• Take-Home Message: Modern Human immune systems are possibly a result of breeding with Neanderthals many years ago.

Pinna 2011

Work CitedAbi-Rached, L.; Jobin, M.J.; Kulkami, S.; McWhinnie, A.; Dalva, K.; Gragert, L; Babrzadeh, F.; Gharizadeh, B.; Luo, M.;

Plummer, F.A.; Kimani, J.; Carrington, M.; Middleton, D.; Rajalingam, R.; Beksac, M.; Marsh, S.G.E.; Maiers, M.; Guethlein, L.A.; Tavoularis, S.; Little, A.; Green, R.E.; Norman, P.J.; and P. Parham. 2011. The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans. Science 334: 89-94.

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Pinna, S., 2011. Neanderthals Boost Our Immune System. <http://drpinna.com/neanderthal-genes-boosts-our-immune-system-23305>

Yong, E., 2011. Did sex with Neandethals and Denisovans shape our immune systems? The jury's still out. Discover Magazine.