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Gerard Francis D. Santos

Pain Reliever: Facts and FallaciesA Medical Students Perspective

Ang heartache kakayanin o. Sa sakit na !di o kaya. . . Me"ena ic Acid#Dol"enal$% &hese 'ere the last 'ords in the () inute co ercial *y +nila* aired on,-(,. &he & ad "eatured a *roken)hearted an 'ho caught his girl"riend cheating. Asthe e ories ca e "lashing *ack/ his e otional pain caused hi to al ost end his li"e.0ventually/ he learned to overco e his agony *y "inding another partner.

1 'ould like to point out three points "ro the video. First/ can Me"ena ic Acid#Dol"enal$ truly relieve severe pain2one 'ith a pain scale o" (- over (- or si ply sakitna !di o kaya% as the & ad clai s3

According to Guyton/ physical pain starts 'ith the transduction o" no4ius sti uliinto nociceptive i pulses such as *radykinin/ and hista ine a ong others.Prostaglandins enhance sensitivity o" the nociceptors/ 'hich are responsi*le "or thetrans ission o" i pulses "ro the peripheral nervous syste to the dorsal horn/ 'here

odulation can take place. 1 pulses 'ill then *e sent to the thala us and corte4 'here pain is perceived. &his is 'here Me"ena ic Acid co es into play. 1t 'orks *y *locking

the e""ect o" cyclo)o4ygenase #567$ en8y es/ 'hich are necessary "or prostaglandin production. 9ence/ stopping the chain o" events at its very onset. 9o'ever/ this

edication is not a*le to target the higher center *ut only a inute part o" the process.&his akes it a 'eak edication only suita*le "or ild to oderate pain/ unlike

edications like opiods/ 'hich target alpha/ delta and kappa receptors/ *oth in the spinaland supraspinal level and are/ thus/ a*le to relieve severe pain. &his akes the state entin the & advertise ent a ere "allacy.

Secondly/ ho'ever/ the state ent Sa sakit na !di o kaya% also has goodi plications. 5o e to think o" it/ the co ercial does not pro ote the use o" theanalgesic negligently i" the pain is still tolera*le. hile Me"ena ic Acid is indeede""ective in controlling pain/ it has dra'*acks 'hen used in long ter . Suchdisadvantages include increased tolerance to such edications and decreased painthreshold. Put si ply/ 'hile individuals perception o" pain vary/ the longer ti e you usean analgesic/ the sooner and "aster you 'ill "eel the pain even at a ini al sti ulus#decreased pain threshold$. &his 'ill then result in a need "or higher dosage o" the

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edication to decrease the pain #drug tolerance$. And the vicious cycle continues. &he& ad/ then/ gives us a re inder that a o ent o" satis"action ay cause a li"eti e o" regrets.

;ast is the co parison *et'een e otional and physical pain. Ang heartache/kakayanin o. Sa sakit na !di o kaya. . . Me"ena ic Acid #Dol"enal$%/ he said. ou survive. 1t "ades. 0 otional pain/on the other hand/ can o"ten *e so intense that it causes physical pain and other sy pto s. >our *ody "ree8es? your knees tre *le? your heart hurts. ;ike in the &co ercial/ the pain lingers and re ains. 0ven i" you "eel like its over/ the e ories'ill haunt you. 1t sho's up in your night ares. 1t cripples you and takes a'ay the littlehope you have le"t. Ang heartache/ kakayanin o/% he said.