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Drug Action Indication Contraindication Side-Effects/AdverseReactions

Nursing Co

Haloperidol- Typical

antipsychotic

Unknown. A butyrophenoneprobably exerts antipsychoticeffects by blockingpostsynaptic dopaminereceptors in the brain.

Psycotic disordersChronic psychosis requiringprolong therapyTourette Syndrome

Patients hypersensitive to drugPatients with parkinsonism, incoma, and CNS depressionUse cautiously in elderly anddeliberated patients; in patientswith history of seizures; severeCV disorders, allergy, glaucoma,and urine retention, and thosetaking anticonvulsants,antiparkinsonians, or lithium.

CNS: Severe extrapyramidalreactions, tardive dyskinesia,seizuressedation, drowsiness,lethargy, headache, insomnia,confusion,

CV: Tachycardia,hypotension,

EEG: Blurred vision

GI: Dry mouth, anorexia,constipation, diarrhea,nausea, vomiting

GU: Urine retention, menstrualirregularities,

Warn patieactivities thalertness acoordinatiothe drugs a

Educate padrowsinessusually subweeks.

Tell patientmouth withor hard can

Warn patiealcohol dur

Drug Action Indication Contraindication Side-Effects/Advese Effects Nursing Re

Akineton- Anticholinergic- Anti parkinsonian

It is a weak peripheralanticholinergic agent withnicotinolytic activity. Thebeneficial effects inParkinson disease andNeuroleptic-inducedextrapyramidal symptomsare believed to be due tothe inhibition of the striatalcholinergic receptors.

Treatment for ParkinsonsdiseaseImprove the parkinsoniansigns and symptoms relatedto antipsychotic drugtherapy.Relieves muscle rigidity,reduces abnormal sweatingand salivation

Hypersensitivity to Biperiden orany component of theformulation.Narrow-angle glaucomaBpwel obstruction, megacolonCaution in patients withobstructive diseases of theurogenital tract; patients withknown history of seizures, andthose with dangeroustachycardia

Side-Effects:CNS: Drowsiness, vertigo,headache, dizziness

Peripheral: Blurred vision, drymouth, impaired sweating,abdominal discomfort,obstipation, tachycardia

Eyes: Mydriasis, photophobia

Adverse-Effects:

Remind paalcohol camay increaand dizzin

Remind clbeing overmay causesweating.

Educate cldrug with a

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CV: Ortho hypotension,bradycardia

CNS: Drowsiness, euphoria,disorientation, agitation,sleep disorder

EEG: Blurred vision

GI: constipation, dry throat,nasal dryness

GU: urinary retention

Take it afteupsets the

Remind totemperatumoisture a

Instruct to

with dentahave reguups.

Drug Action Indication Contraindication Side-Effects/Advese Effects Nursing Re

Chlorpromazine- Typical

Antipsychotic

Unknown. A piperidinephenothiazine that probablyblocks postsynapticdopamine receptors in thebrain.

Psychosis, maniaNausea, VomitingTetanus

Patients hypersensitive todrug, in those with CNSdepression, and those in comaUse cautiously in elderly anddeliberated patients and inpatients with hepatic or renaldisease, severe CV disease,respiratory disorders,hypocalcemia,Use cautiously in acutely ill, ordehydrated children.

Side-Effects:CNS: extrapyramidalreactions, sedation, tardivedyskinesia,pseudoparkinsonism

CV: orthostatic hypotension

GI: dry mouth, constipation

GU: urine retention

Skin: mild photosensitivityreactions

Adverse Effects:CNS: Seizures, NMS

Hema: Leukopenia,

Obtain basmeasuremestarting themonitor regorthostatic

Monitor for dyskinesia

Warn to avrequire alercoordinatiodrug are kn

Advise not or break excapsule forswallowing

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agranulocytosis,thrombocytopenia, anemia Educate to

while taking

Drug Action Indication Contraindication Side-Effects/Advese Effects Nursing Re

DiphenhydramineAntihistamine

Competes with histamine forH1-receptorsites. Prevents, but doesntreverse,histamine-mediatedresponses, particularly thoseof the bronchial tubes, GItract, uterus,and blood vessels.Structurally related tolocal anesthetics, drugprovides local anesthesiaand suppresses cough reflex

Rhinitis, allergy symptoms,motion sickness, Parkinsonsdisease

Contraindicated in patientshypersensitiveto drug Avoid use in patients takingMAOinhibitors. Use with caution in patientswith prostatichyperplasia, asthma, COPD,increasedintraocular pressure,hyperthyroidism, CVdisease, and hypertension.

Children younger than age 12should usedrug only as directed byprescriber.

CNS: drowsiness, sedation,sleepiness,dizziness, seizures, confusion,insomnia, headache, vertigo,fatigue,restlessness, tremor,nervousness.CV: palpitations, hypotension,tachycardia.EENT: diplopia, blurred vision,nasalcongestion, tinnitus.GI: dry mouth, nausea,

epigastric distress,vomiting, diarrhea,constipation, anorexia.GU: dysuria, urine retention,urinary frequency.Hematologic:thrombocytopenia,agranulocytosis,hemolytic anemia.Skin: urticaria,photosensitivity, rash

Stop drug 4diagnostic testing. Injection fI.M. adminonly. Dizzinesssedation, sytoxicity, pastimulationhypotensioare more likelderly

patients.food or milkdistress.Warn patiealcohol andactivities thalertness uCNS effectknown.