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present, but it’s inadequate,”
he says. “Could that be because
mammals don’t have enough
[heart] stem cells? We need to
understand what is holding the
system back so that we can devise
a strategy to turn that brake off.”
But Kenneth Chien of the
Massachusetts General Hospital
in Boston isn’t convinced. “The
most important question now is:
can you identify that new pool?
Are they pre-existing immature
cardiac muscle cells? Or are they
[stem cells] from the heart or
elsewhere in the body?”
remained the same, suggesting
that adult mice don’t normally
make new heart muscle cells.
When the team induced heart
attacks in the mice, the number
of stained cells dropped to 70 per
cent, while the overall number of
heart cells remained about the
same, suggesting that new muscle
cells can form in response to
injury (Nature Medicine, DOI:
10.1038/nm1618).
Lee thinks that the adult
mouse heart has a limited ability
to repair itself. “The mechanism
to activate cardiac regeneration is
TATOOINE, eat your heart out. The
fictional planet in Star Wars that orbits two suns stands to be
upstaged by a quadruple star
system 150 light years from Earth
that may host a planet.
The system, called HD 98800,
consists of two pairs of stars in
which the partners in each pair
orbit one another and the pairs in
turn travel around each other.
Observations by the Spitzer Space
Telescope show two concentric
rings of dust around one of the
pairs, which suggests a planet
may be circling there.
Elise Furlan of the University
of California, Los Angeles, and
colleagues say the empty space
between the two rings might have
been cleared out by the gravity of
a planet orbiting there. One ring
lies about twice as far as the Earth
lies from the sun, while the other,
which is denser, lies about six
times the Earth-sun distance.
Since any coalescence in the
dust is not expected to be stable
at the location of the inner ring,
Furlan says if there is a planet, it
is more likely to be found near the
outer ring. However, it is possible
the region between the rings
could simply have been cleared by
the gravity of the four stars.
Four-star lodgings
for a planet
MOTORISTS are not the only ones to
benefit from high-speed roads. Life
in the fast lane also helps plant seeds
travel far from home. So say Moritz
von der Lippe and Ingo Kowarik of
the Technical University of Berlin,
Germany, who have shown that
traffic may account for up to half of
seed dispersal near motorways.
Seeds may stick to vehicles or be
swept along in the airflow created by
traffic. To find out how common this
is, the researchers left seed traps deep
within several long road tunnels,
ensuring that the seeds collected were
transported by vehicles rather than
the wind. Over a year, they trapped
more than 6000 seeds, from which
they calculated that vehicle transport
is responsible for between 635 and
1579 seed falls per square metre
per year. That is roughly the level
of natural seed fall in sparsely
vegetated areas, suggesting that
vehicle transport could double
the effectiveness of seed dispersal
if such areas are near busy roads
(Conservation Biology, DOI: 10.1111/
j.1523-1739.2007.00722.x).
Among their samples, von der
Lippe and Kowarik found seeds from
39 problematic invasive species that
are damaging biodiversity in some
parts of the world. “Many countries,
including the US, spray roadsides with
herbicides,” says von der Lippe.
DO YOU remember life’s highs and
lows? If not, perhaps you can blame
your genes. It looks as if a gene that
influences how brains respond to
neurotransmitters may affect our
ability to recall emotional events.
Such incidents trigger the release
of noradrenalin, which stimulates
memory storage, says Dominique de
Quervain at the University of Zurich
in Switzerland. Since the ability to
recall emotional events varies from
person to person, he wondered if
a variant of ADRA2B, the gene that
codes for the noradrenalin receptor,
could be involved.
To find out, his team selected
photos of various events, some
unlikely to rouse emotions, others
with a strong emotional charge,
positive or negative. Then they
showed the pictures to two large
groups of people and later asked
them which ones they remembered.
One group comprised traumatised
survivors of the Rwandan genocide,
the other healthy Swiss citizens. In
both groups, people with the ADRA2B
variant were “substantially more
likely” to remember both positive
and negative images than people
with other forms of the gene (Nature Neuroscience, DOI: 10.1038/nn1945).
However, the Rwandans with the
variant had far higher recall of the
negative emotional events in the
experiment than the Europeans who
carried it. The variant is carried by
30 per cent of Caucasians and 12 per
cent of Africans.
THE discovery of heart stem cells
in 2006 raised hopes that new
treatments for heart disease
would soon follow. Now, it seems
heart stem cells may already help
to repair the damage after a heart
attack, if only to a limited degree.
Richard Lee of the Harvard
Medical School and colleagues
genetically engineered mice so
that their heart muscle cells could
be stained with a fluorescent
protein. Only 80 per cent of the
heart muscle cells in young mice
picked up the stain. However,
as the mice aged, this level
PUNC
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The heart can repair itself – up to a pointMemories are made of this
Beware invasion by hitch-hiking seeds
www.newscientist.com 4 August 2007 | NewScientist | 17
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