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Interdisciplinary meeting

“Bone and Soft Tissue Sarcomas: State of the Art and Perspectives 2015”

Friday and Saturday, 17th and 18th of April 2015 Klinikum rechts der Isar, Lecture Hall B

Klinikum rechts der Isar Technische Universität München

13 CME pointsWilhelm Sander Unit for Bone and Soft Tissue Sarcomas Orthopedic Department, Klinikum rechts der Isar Technische Universität München

Wilhelm Sander-StiftungRoman-Herzog-KrebszentrumComprehensive Cancer Center

The Symposium is supported by:

For registration please contact the secretary Ms Dagmar Kluge Telephone 0049 89 4140-2283 Fax 0049 89 4140-7644 E-Mail dagmar.kluge@mri.tum.de

Registration fee 50,00 Euro Bank Bayerische Landesbank Bank code 700 500 00 Account 20 272 IBAN DE82700500000000020272 BIC BYLADEMM

Reason for Payment 881 000 1317 (absolutely necessary)

Location:Klinikum rechts der Isar Technische Universität MünchenIsmaninger Straße 22, 81675 München, Lecture Hall B

Please use public transportation. There is a shortage in parking.

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Speakers

Prof. Dr. Stefan Bielack Ärztlicher Direktor Klinik Pädiatrie 5 Klinikum Stuttgart

Prof. Dr. Stefan Burdach Direktor Klinik und Poliklinik für Kinder und Jugendmedizin Klinikum rechts der Isar TU München

Prof. Dr. Stefanie E. Combs Direktorin Klinik für RadioOnkologie und Strahlentherapie Klinikum rechts der Isar TU München

Prof. Dr. Jürgen Dunst Direktor Klinik für Strahlentherapie Universitätsklinikum Schleswig-Hol-stein, Lübeck

Prof. Dr. Rüdiger von Eisenhart-RotheDirektor Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar TU München

Prof. Dr. Jürgen Freyschmidt Beratungsstelle und Referenz-zentrum für Osteoradiologie Klinikum Bremen Mitte

Priv. Doz. Dr. Hans Gollwitzer Oberarzt Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar TU München

Prof. Dr. Reiner Gradinger Ärztlicher Direktor Klinikum rechts der Isar TU München

Prof. Dr. Jendrik Hardes Sektionsleiter Tumororthopädie und Revisionschirurgie Klinik für Allgemeine Orthopädie und Tumororthopädie Universitätsklinikum Münster

Dr. Matthias Hauschild Leitender Oberarzt Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar TU München

Lee J. Helman, M.D. Senior Investigator Pediatric Oncology Branch Scientific Director for Clinical Re-search, Center for Cancer Research National Cancer Institute Bethesda, Maryland, USA

Dr. Martin Henninger Nuklearmedizinische Klinik Klinikum rechts der Isar TU München

Priv. Doz. Dr. Konstantin Holzapfel Oberarzt Institut für Radiologie Klinikum rechts der Isar TU München

Prof. Dr. Ewa Koscielniak Leitende Oberärztin Klinik Pädiatrie 5 Klinikum Stuttgart

Prof. Dr. Laszlo Kovacs Ltd. Oberarzt Klinik für Plastische Chirurgie und Handchirurgie Klinikum rechts der Isar TU München

Priv.-Doz. Dr. Andreas Heinrich Krieg Leitender Arzt Abteilung für Kinderorthopädie – Tumoren und Korrekturen Universitäts-Kinderspital beider Basel, Schweiz

Priv. Doz. Dr. Kuhlencordt Stellvertr. Leiter Sektion Angiologie Medizinische Klinik u. Poliklinik IV Klinikum der Universität München Campus Innenstadt

Dr. B. Lehner Leiter Sektion Orthopädische Onkologie Klinik für Orthopädie und Unfallchirurgie Universitätsklinikum Heidelberg

Univ. Prof. Dr. Andreas Leithner Klinikvorstand Klinik für Orthopädie und Orthopädische Chirurgie Medizinische Universität Graz, Österreich

Dr. Ulrich Lenze Abteilung für Kinderorthopädie Universitäts-Kinderspital beider Basel, Schweiz

Priv. Doz. Dr. Lars Lindner Geschäftsführer SarKUM Medizinische Klinik und Poliklinik III Klinikum der Universität München Campus Großhadern

Prof. Dr. Dr. Hans Rechl Oberarzt Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar, TU München

Priv. Doz. Dr. Ingo Ringshausen Cambridge, United Kingdom

Priv. Doz. Dr. Barbara Röper Ltd. Oberärztin Klinik für RadioOnkologie und Strah-lentherapie Klinikum rechts der Isar, TU München

Prof. Dr. Maximilian Rudert Direktor Orthopädische Klinik König-Ludwig-Haus Universitätsklinikum Würzburg

Prof. Dr. Pietro Ruggieri Head of IV Department of Orthopedics Musculoskeletal Oncology Istituto Rizzoli, Bologna, Italien

Dr. Johannes Schauwecker Oberarzt Klinik für Orthopädie und Sportorthopädie Klinikum rechts der Isar TU München

Priv. Doz. Dr. Katja Specht Oberärztin Institut für Pathologie und Pathologische Anatomie Klinikum rechts der Isar, TU München

Priv. Doz. Dr. Irene Teichert von LüttichauOberärztin Klinik und Poliklinik für Kinder und Jugendmedizin Klinikum rechts der Isar, TU München

Prof. Dr. Reinhard Windhager Direktor Universitätsklinik für Orthopädie Medizinische Universität Wien, Österreich

Prof. Dr. Klaus Wörtler Ltd. Oberarzt Institut für Radiologie Klinikum rechts der Isar, TU München

Dear colleagues, ladies and gentlemen,

The Wilhelm Sander Unit for Bone and Soft Tissue Sar-comas at university hospital Klinikum rechts der Isar, cordially invites you to our interdisciplinary meeting on „Bone and Soft Tissue Sarcomas: State of the Art and Perspectives 2015“. The first day of this two-day-meeting focusses on dia-gnostics, radiotherapy and chemotherapy. The second day covers the surgical treatment. In particular, we add-ress orthopedic surgeons, radiologists, pediatricians, internal oncologists and radiation therapists - reflecting the interdisciplinary approach to this difficult group of diseases.Sarcomas are malignant tumors of the musculoskeletal system and rather rare, counting for about 2000 new cases each year in Germany. Due to this fact and their biological and clinical heterogeneity, diagnosis and treatment remain a challenge for all involved disciplines.We are very pleased that again we can offer a compre-hensive programme with nationally and internationally distinguished speakers and chairpersons and we ex-pect a highly interesting interdisciplinary meeting. Topics include selected issues of histopathological clas-sification, new aspects of staging, but also new opportu-nities of documentation and quality control as an aspect of clinical research. New ways in drug therapy and ra-diation therapy are presented and discussed as well as the significance of patient follow-up.The second day of the meeting focusses on surgical therapy. Special reconstruction techniques as well as their characteristics and results are presented and dis-cussed in depth. The management of complications and possible solutions to them are another focus. We would be very pleased to see you at this meeting and we are looking forward to welcoming you in Munich.

Prof. Dr. Rüdiger Prof. Dr. Dr. von Eisenhart-Rothe Hans Rechl

Friday, 04/17/2015

09:50 a.m. Welcome and Opening Remarks Prof. Dr. Rüdiger von Eisenhart-Rothe (Munich)

I: Diagnosis of Bone and Soft Tissue Sarcomas Chair: Prof. Dr. K. Wörtler (Munich) Prof. Dr. J. Freyschmidt (Bremen)

10:00 a.m. Diagnostic imaging of bone sarcomas Prof. Dr. J. Freyschmidt (Bremen)

10:25 a.m. New aspects of local staging in musculoskeletal tumors Priv. Doz. Dr. K. Holzapfel (Munich)

10:50 a.m. The sarcoma data-base of the musculoskeletal tumor center: A valuable tool for quality control and interdisciplinary clinical studies Dr. U. Lenze (Munich, Basel)

11:15 a.m. Value of PET-MRI and PET-CT of musculoskeletal tumors Dr. M. Henninger (Munich)

11:40 a.m. Classificationofsarcomas:Fromlight microscopy to molecular genetic diagnostics Priv. Doz. Dr. K. Specht (Munich)

12:05 a.m. Lunch and industrial exhibition

II: Chemotherapy of Bone and Soft Tissue Sarcomas Chair: Prof. Dr. St. Burdach (Munich) Priv. Doz. Dr. I. Ringshausen (Cambridge, UK)

13:00 p.m. Chemotherapy of bone sarcomas - “State of the Art“ (Key-note-lecture) Prof. Dr. St. Burdach (Munich) Lee J. Helman (MD, USA)

13:25 p.m. Chemotherapy of soft tissue sarcomas in adults: indication and current status Priv. Doz. Dr. L. Lindner (Munich)

13:50 p.m. Chemotherapy of soft tissue sarcomas in adolescents Prof. Dr. E. Kościelniak (Stuttgart)

14:15 p.m. The value of follow-up in bone sarcomas Prof. Dr. St. Bielack (Stuttgart)

14:45 p.m. Coffee break, industrial exhibition

III: Radiotherapy Chair: Prof. Dr. St. Combs (Munich) Prof. Dr. J. Dunst (Lübeck)

15:20 p.m. Significanceofparticletherapy in the treatment of sarcomas Prof. Dr. St. Combs (Munich)

15:45 p.m. Radiotherapy in bone sarcomas Prof. Dr. J. Dunst (Lübeck)

16:10 p.m. Pros and Cons of adjuvant and neoadjuvant radiotherapy in soft tissue sarcomas Priv. Doz. Dr. B. Röper (Munich)

16:35 p.m. Closing Remarks and Organization Prof. Dr. Dr. H. Rechl

Saturday, 04/18/2015

08:15 a.m. Opening Remarks Prof. Dr. R. von Eisenhart-Rothe (Munich)

IV: Surgical Treatment Chair: Prof. Dr. R. Windhager (Vienna) Prof. Dr. R. Gradinger (Munich)

08:25 a.m. Biological reconstruction following resection of bone and soft tissue tumors Prof. Dr. R. Windhager (Vienna)

08:50 a.m. Current status in the treatment ofaggressivefibromatosis Prof. Dr. A. Leithner (Graz)

09:15 a.m. Extracorporal irradiation and reimplantation of bone sarcomas Priv. Doz. Dr. A. Krieg (Basel)

09:40 a.m. Pelvic chondrosarcoma: Therapy, results and prognosis Prof. Dr. P. Ruggieri (Bologna)

10:05 a.m. Extendable prosthesis versus rotationplasty Prof. Dr. J. Hardes (Münster)

10:30 a.m. Surgical possibilities in the reconstruction of defects following tumor resection Prof. Dr. L. Kovacs (Munich)

10:55 a.m. Relevance and treatment of tumor associated venous thrombosis Priv. Doz. Dr. P. Kuhlencordt (Munich)

11:20 a.m. Lunch, industrial exhibition

V. Management of Complications in Megaprostheses Chair: Prof. Dr. M. Rudert (Würzburg) Prof. Dr. J. Hardes (Münster)

13:00 p.m. Modes of failure in megaprostheses Prof. Dr. R. v. Eisenhart-Rothe (Munich)

13:25 p.m. Diagnostic algorithm for infected megaimplants Dr. J. Schauwecker (Munich)

13:50 p.m. The infected tumor prosthesis: Ways to solve the problem Dr. B. Lehner (Heidelberg)

14:15 p.m. Reconstruction by individual pelvic replacement in tumor surgery and complex implant loosening Dr. M. Hauschild (Munich)

14:40 p.m. Biofunctionalization of the implant-surface in therapy and prophylaxis of infections Priv. Doz. Dr. H. Gollwitzer (Munich)

15:05 p.m. Closing remarks Prof. Dr. R. von Eisenhart-Rothe (Munich)

15:10 p.m. End of Conference

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Sign up until March, 31th, 2015, addressed to:Wilhelm Sander Unit for Bone and Soft Tissue Sarcomas Klinikum rechts der IsarDagmar Kluge

Phone: 0049 89 4140 2283 Fax: 0049 89 4140 7644 E-Mail: dagmar.kluge@mri.tum.de

Interdisciplinary meeting“Bone and Soft Tissue Sarcomas: State of the Art and Perspectives 2015”

Sign UpWilhelm Sander-Stiftung