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EUROACTION A model for secondary and primary preventive care to achieve ‘25 by 25’ Professor David A Wood Garfield Weston Professor of Cardiovascular Medicine International Centre for Circulatory Health Imperial College London United Kingdom

EUROACTION A model for secondary and primary preventive ...€¦ · A model for secondary and primary preventive care to ... Centro de Salud de San Pau. ... • Fruits and vegetables:

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EUROACTIONA model for secondary and primary preventive care to

achieve ‘25 by 25’

Professor David A WoodGarfield Weston

Professor of Cardiovascular MedicineInternational Centre for Circulatory Health

Imperial College London United Kingdom

Cardiopulmonary rehabilitation

“Cardiac rehabilitation is a branch of rehabilitation medicine dealing with

optimizing physical function in patients with cardiac disease”

Wickipedia September 2nd 2013

Cardiac rehab §°

95% CI Secondary prevention ¶

95% CI

Total mortality 0.80 0.68, 0.93 0.85 0.77, 0.94

CHD mortality 0.74 0.61, 0.90 - -

Myocardial re-infarction 0.79 0.57, 1.09 0.83 0.74, 0.94

§ Taylor R et al, Am J Med 2004; 116:682-692 ¶ Clark A M et al Annals of Internal Medicine 2005;143:659-672. °Heran B S, et al Cochrane Database of Systematic Reviews 2011

Randomised controlled trials of cardiac rehabilitation and secondary

prevention

Secondary preventionAll cause mortality

Secondary preventionAll cause mortality

Treatment Control Relative Risk

95% CI

Programmewith no exercise

4598 4604 0.87 0.76, 0.99

Programmewith exercise

2404 2251 0.88 0.74, 1.04

Exercise only 1165 1120 0.72 0.54, 0.95

Overall* 8167 7975 0.85 0.77, 0.94

*p=0.001

Clark A M et al Annals of Internal Medicine 2005;143:659-672

Secondary PreventionRecurrent myocardial infarction

Secondary PreventionRecurrent myocardial infarction

Treatment Control Relative Risk

95% CI

Programmewith no exercise

2787 2742 0.86 0.72, 1.03

Programmewith exercise

2075 1922 0.62 0.44, 0.87

Exercise only 1124 1073 0.76 0.57, 1.01

Overall* 5986 5737 0.83 0.74, 0.94*p=0.002

Clark A M et al Annals of Internal Medicine 2005;143:659-672

Cardiac rehabilitation+

Secondary prevention

Cardiac rehabilitation is a branch of rehabilitation medicine dealing with

optimizing physical function in patients with cardiac disease.

While the ‘glue’ of cardiac rehabilitation is exercise, programmes are evolving to

become comprehensive prevention centerswhere all aspects of

care are delivered.

Wickipedia September 2nd 2013

Comprehensive prevention centers where all aspects of care are

delivered.

Wickipedia September 2nd 2013

Lifestyle (smoking cessation, diet, physical activity) intervention, taking account of

psycho-social factors, and using a behavioural approach

Measuring, monitoring and managing other risk factors (blood pressure, lipids and

glucose) to target Understanding of, and adherence with,

cardioprotective drug therapies for life

SCORE: the European Risk Prediction SystemSCORE: the European Risk Prediction System

1994199820033rd Joint European Societies Task Force

2004European Society of Cardiology

Score enabled HeartScore, an interactive tool

• 12 European cohort studies• wide geographic spread of

countries at different levels of cardiovascular risks

• 3-million person-years of observation

• 7,934 fatal cardiovascular events

Data from:

SCORE

SCORE: the European Risk Prediction SystemSCORE: the European Risk Prediction System

1994199820033rd Joint European Societies Task Force

2004European Society of Cardiology

Score enabled HeartScore, an interactive tool

• 12 European cohort studies• wide geographic spread of

countries at different levels of cardiovascular risks

• 3-million person-years of observation

• 7,934 fatal cardiovascular events

Data from:

SCORE

Total risk assessment

SCORE

SCORE: the European Risk Prediction SystemSCORE: the European Risk Prediction System

1994199820033rd Joint European Societies Task Force

2004European Society of Cardiology

Score enabled HeartScore, an interactive tool

• 12 European cohort studies• wide geographic spread of

countries at different levels of cardiovascular risks

• 3-million person-years of observation

• 7,934 fatal cardiovascular events

Data from:

SCORE

Total risk assessment

Total risk management

Lifestyle (smoking cessation, diet, physical activity) intervention, taking account of

psycho-social factors, and using a behavioural approach

Measuring, monitoring and managing other risk factors (blood pressure, lipids and

glucose) to target Understanding of, and adherence with,

cardioprotective drug therapies for life

Primary

Prevention

Secondary

Prevention

Wood D A, et al Lancet 2008; 371: 1999-2012

EUROACTIONA European Society of Cardiology demonstration project:8 countries and 24 hospital and general practice centres

General hospitals and general practices

Dr Antonio Salvador, Cristina Buigues, Ana Bonet, Arancha Ruescas and Rosario Cuevas

Hospital General de Dr. Peset

Dr Jorge Navarro and Gemma Medez Perez

Centro de Salud de San Pau

Ambulatory nurse-coordinated multidisciplinary approach

The EUROACTION team in Boldrini Hospital, Thiene, Italy The EUROACTION nurse and

the lead GP in Hoensbroek, The Netherlands

Lifestyle change in families• No smoking• Saturated Fat: <10% total

Energy• Fruits and vegetables:

>400g/day• Fish: >20g/day• Oily Fish: >3 times/week• 30-45 minutes of physical

activity at 60–75% of the average maximum heart rate on four-five days of the week

• Weight reduction ≥ 5%• Waist <94 cm in men and

<80 cm in women

Smoking cessation

IncreasingPhysical activity

Healthy eating,Weight

management

Family based lifestyle programme

Sweden

Poland

Health promotion workshops

Gemona, Italy Valencia, Spain

Thiene, Italy

Halmstad, Sweden Valencia, Spain

Supervised hospital and home based physical activity

programme

One year assessment

Identification

Intervention

Randomisation

INT

PROGRAMME16 week hospital

1 year primary care

1965PATIENTS

UC

A CLUSTER RANDOMISED CONTROLLED TRIAL

Initial assessment

580SUB-SAMPLE

2179PATIENTS

2778PATIENTS

1632PARTNERS

910PARTNERS

626PARTNERS

2613PATIENTS

1999PATIENTS

1634PARTNERS

698PARTNERS

EUROACTION: HospitalSmoking cessation at one year in coronary patients who were smokers in the month

prior to their event

p = 0.06

+ 10% ( - 0.3% to + 21%)

EUROACTION: Hospitals Smoking status at baseline, 16 weeks and one year 

(validated breath CO) in coronary patients

Proportions of patients achieving the European targets for a

healthy dietHospital General Practice

Intervention Usual Care

p = 0.005

p = 0.26

p = 0.13

p = 0.009

p = 0.004

p = 0.91

p = 0.04

Proportions of partners achieving the European targets for a

healthy dietHospital General Practice

p = 0.002

p = 0.42

p = 0.09

p = 0.31 p = 0.002

p = 0.98

p = 0.77

Intervention Usual Care

P = 0.002

General Practice+ 29% ( + 11% to + 48%)

Hospital+ 36% (+20% to + 51%)

P = 0.001

Proportion of patients achieving European Guidelines for physical

activity

Proportion of partners achieving European Guidelines for physical

activity

P = 0.06

General PracticeHospital

p = 0.03

+ 19% (- 0.6% to + 38%) + 27% (+ 4% to + 50%)

Proportion of patients achieving the European target for

blood pressure

P = 0.04

General PracticeHospital

p = 0.03

+ 17% (+ 2% to + 32%)+ 10% (+ 0.6% to + 20%)

Intervention Usual Care

Proportion of patients achieving European target for blood pressure

p = 0.04*

+ 17% (+ 0.5% to + 33%)

* random effects modelling

%

+ 19% (+ 1% to + 37%)

p = 0.04*

Patients without diabetes

Patients with diabetes

Proportion of patients on cardiovascular protective drug therapy

General PracticeHospital

Intervention Usual Care

p=0.28

p=0.16

p=0.26

p=0.53

p=0.04

p=0.06

p=0.91p=0.02

p=0.24

p=0.03

0.19

‘EUROACTION set a new standard for preventive

cardiology – in both secondary and primary prevention

TerminologyCardiac rehabilitation

Cardiovascular rehabilitationRehabilitation and secondary

preventionCardiac rehabilitation and

preventionCardiovascular prevention and

rehabilitation

NICE Guideline: MI - secondary prevention

Cardiac rehabilitation programme is defined as:

ExerciseHealth education and information

Psychology and social support

NICE Guideline: MI - secondary prevention

Cardiac rehabilitation does NOT include:Lifestyle changes after MI:

Smoking cessationChanging dietary regimen

Alcohol consumptionWeight managementDrug therapy after MI

TerminologyCardiac rehabilitation

Cardiovascular rehabilitationRehabilitation and secondary

preventionCardiac rehabilitation and

preventionCardiovascular prevention and

rehabilitation

Cardiac rehabilitation and secondary prevention for patients with

established atherosclerotic disease+

Primary prevention for asymptomatic individuals at high risk of developing CVD including patients with diabetes

mellitus, CKD and other high risk diseases

Integrate secondary and primary prevention in one programme

MyAction in public leisure facilities

MyAction is a modern preventive cardiology programmeintegrating secondary

and primary prevention in prevention centres

Victoria Medical Centre

St John & St Elizabeth, St. Johns Wood

Stowe Centre, Harrow Rd

MyAction Westminster: Centres

St Marys

Hospital

Victoria Medical Centre

St John & St Elizabeth, St. Johns Wood

Stowe Centre, Harrow Rd

MyAction Westminster: Prevention Centres

St Marys

Hospital

MyActionCommunity based

Integrates secondary and primary prevention

Nurse led and multidisciplinary:dieticians,

physiotherapists, psychologist, community cardiologist

Family centredProtocol based

Measures outcomes

The MyAction Teams

PreventionRecovery

Well being

Todays service is preventive cardiology

“Prevention, recovery and well being”

Oxford University

Presswww.oup.org

MSc Preventive Cardiology

www.imperial.org