ASSESSING READINESS TO OFFER NEW DEGREE PROGRAMS

Master of Science in Biomedical Engineering, 09/08/2011Assessing Readiness to Offer New Degree Programs is a supplemental campus-based document that will

a) Inform the academic program development process and b) Illustrate the unit’s readiness to offer the proposed degree program.

The proposing unit is expected to a) Submit the assessing readiness document with the proposed program’s planning document and b) Update the assessing readiness document as unit conditions change for submission with the proposed

program’s request to establish.

Part One: Assessing Need for the Program

Need for the ProgramAs the population ages, the need for advanced medical tools, devices and diagnostics increases along with a need to improve our understanding of disease states. Thus as this need increases so does the demand for biomedical engineers. Due to their unique background, biomedical engineers have one foot grounded in the medical field and one foot grounded in engineering principles. By straddling these fields, biomedical engineers form a bridge upon which medical need, clinical practice, creativity, collaboration and research can travel freely from one side to the other. Our students will have a direct impact on the lives and health of those living in eastern North Carolina.

According to the Bureau of Labor Statistics, the employment growth for biomedical engineering will increase by 72% over the next ten years illustrating an increasing demand for people in this field. In addition the Labor Market Information Division of the Employment Security Commission of North Carolina predicts a 38% increase in biomedical engineering jobs from 2006-2016. Thus there is a demand within the state of North Carolina for biomedical engineers.

Table 1: BLS Growth Projections (in thousands) for Biomedical Engineering and Related Occupations http://www.bls.gov/oco/ocos027.htm

Occupational title SOC Code

Employment, 2008

Projected employment,

2018

Change, 2008-18Number Percent

Biomedical Engineer 17-2031 16,000 27,600 11,600 72

Graduates of the program will be highly qualified candidates and prepared for the Brody School of Medicine (BSOM), the School of Dental Medicine, current PhD programs offered in the BSOM and positions in industry. In addition, this program will prepare our students to compete in PhD, medical and dental programs at other UNC constituent institutions. Upon completion of this program students may enter the education profession, improving the STEM teaching pool for eastern North Carolina. Students will be qualified to compete for programs and fellowships in government sponsored research laboratories.

Fit with Strategic PlanThis unique program, which targets an emerging and advanced technological field, integrates with key components of the ECU mission statement: to serve through education, to serve through research and creative activity, and to serve through leadership and partnership. The proposed MS in biomedical engineering is consistent with and supports these components. This MS program:

Offers a unique graduate education option preparing engineers and scientists to meet the challenges of biomedical discovery and applications of engineering to medicine in service to the people of North Carolina, their health and their welfare.

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Provides opportunities for partnership with the Brody School of Medicine, School of Dental Medicine, College of Allied Health Sciences, industry, government, and defense system organizations.

Enhances new and emerging research opportunities for faculty in the Brody School of Medicine, School of Dental Medicine, College of Allied Health Sciences and the Department of Engineering to form partnerships in an emerging field.

Focuses on development of technology professionals in a key field and promotes development of strong linkages and interactions with the industrial, business, and public sector organizations of eastern North Carolina.

Advances the art of biomedical engineering.

The proposed MS program specifically addresses the following ECU Strategic Directions and related sub elements as presented in ECU Tomorrow:

Education for a new century: We will be responsive to the changing demands of the economy, offering excellent undergraduate and graduate programs that provide the global skills and knowledge necessary for success in the twenty-first century.

Economic Prosperity in the East: We will invest in academic programs that give individuals the right skills and tools needed to compete and thrive in a twenty-first-century workplace. We will invest in programs that improve access to our resources for communities and individuals. We will provide ongoing educational and learning opportunities to support the continued development of a competitive workforce for North Carolina.

Biomedical engineering is a twenty-first century career field which meets the demands of the economy for excellent graduate programs which allow ECU graduates to compete in the global economy. In addition, this degree has the potential to provide a substantial positive impact, improving the resources for the regional community to improve health care and jobs. Globalization of both engineering and the overall field of healthcare has been increasing over the past 10-20 years and is continuing to increase. Graduates of the proposed program will have a strong background in both fields and will be able to compete and contribute to this growing global economy.

Since 2004, the ECU BS in engineering program has had a positive impact on industry and economic development in eastern North Carolina. Faculty from the biomedical and bioprocess undergraduate concentrations work regularly with industry and economic development professionals from across the region. The Department of Engineering’s active Engineering Advisory Board (EAB) includes two economic development professionals, one from Pitt County and one from the East Region. The time and effort spent by the 40+ members of the EAB are testament to the fact that local industry cares very much about the program. A number of the EAB members are from healthcare-related industries, providing internships and senior capstone project opportunities. Members of the EAB are strong contributors to the department.

ECU will increase investment in innovation and research: We will be the third-largest research university in the University of North Carolina system, exceeding $100 million in external support for our programs. We will lead in innovation in health sciences and information technology and seek to develop products that compete in the growing knowledge-based economy. We will invest in interdisciplinary research centers that will support the region’s growth in health care, tourism, education, marine trades, and biotechnology. We will focus on developing applied, translational, and externally focused research that emphasizes the economic and physical health of our citizens.

Health Care and Medical Innovation: ECU will save lives, cure diseases, and positively transform the quality of health care for the region and state. ECU will expand our research in health sciences with a particular emphasis on the health concerns of the region and state. We will expand biomedical and health-related research funding to $75 million annually.

The MS in biomedical engineering will have a positive impact on the research productivity of the university, support innovation in health sciences, support interdisciplinary research improving health care and biotechnology, and support overall improvement of the health of the citizens of North Carolina. By emphasizing the application of engineering and mathematics to medical research, the proposed program advances the university’s focus on improving student STEM proficiency.

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Impact on other Unit ProgramsThe proposed program does not compete with any program either within the Engineering Department, or within the College of Technology and Computer Science generally. This program will be the first engineering graduate program available at ECU.

More broadly, the proposed MS in biomedical engineering complements many programs in a variety of colleges across both campuses of ECU. For example, the new graduate engineering program integrates well with the MS in biomedical sciences, offered by the BSOM. The biomedical science program emphasizes basic science, medical, pharmaceutical, and biotechnology research.

In addition, the proposed program integrates very well with the interdisciplinary doctoral program in biological sciences (IDPBS). This program currently offers graduate curricula and research in the areas of biology, chemistry and biomedical sciences. The proposed program will complement these research areas, and will expand course selection for graduate students both in engineering and in the above disciplines. Drs. Bossetti and George have been accepted as participants in the IDPBS. The experience gained in advising students in the IDPBS will translate well to advising students in the proposed MS in biomedical engineering.

The average enrollment over the next five years is estimated to be approximately 10 students per year although this number may increase when additional faculty are hired. The five year cumulative enrollment target is 25 students. This program will attract quality students from the Department of Engineering’s BS program, Thomas Harriot College of Arts and Sciences, pre-med students with quantitative research interests, and basic science and engineering students from across the state. Comparison to Similar Programs in Other UniversitiesWithin North Carolina, there are five universities offering masters in biomedical engineering (NCA&T, UNC/NCSU Joint Department of Biomedical Engineering (2), Wake Forest (joint program with Virginia Tech) (10), and Duke (17)), two of which are private universities. The numbers in parentheses indicate the number of MS degrees awarded in AY 2008-09 (source is ASEE Profiles). Therefore there is still a need to be fulfilled within the state of North Carolina for the training of biomedical engineers. East Carolina University has an advantage, both nationally and regionally, as the only university within the University of North Carolina that offers academic programs in engineering, medicine, dentistry, business and allied health on one campus. This proximity of complementary programs provides an unequaled opportunity for collaboration and professional growth of faculty, staff, and students.

This program will expand research and competitive, externally funded grant opportunities for faculty in engineering and other collaborating departments. The curriculum development team will design an innovative research intensive curriculum founded on engineering education research. Such an innovative curriculum would be competitive for extramural funding and national recognition.

Accreditation StandardsThere are no standard accrediting bodies for graduate programs in biomedical engineering.

Part Two: Assessing Readiness of Current Faculty

Complete the Faculty Information Sheet (attached, with instructions for downloading from Sedona) for each individual who will serve as a core faculty member, actively involved in delivering the proposed program.

Please see attached.

Provide a summary of faculty readiness in the unit to include the cumulative totals of the following:

Faculty Readiness Summary (with emphasis on the last five years)Number of core faculty at each rank who will be actively engaged in this program

Professor 1Associate Professor 3Assistant Professor 3

Number of core faculty with experience directing theses/dissertations 5

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Number of scholarly and professional activities related to proposed degree (with emphasis on the past 5 years):Number of publications related to proposed degree 39Number of grants & contracts submitted and awarded related to proposed degree 38Invited research presentations outside ECU 89Patents/disclosures/copyrights 12Participation in scholarly collaborations with other universities, laboratories, & centers:Number of faculty

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Service on related national/international boards or committees: Number of faculty 7

Part Three: Assessing Adequacy of Instructional/Research Facilities and Personnel to Support the Program

Instructional and Research Facilities Implementation of the proposed degree program will require additional laboratory and office space beyond the facilities employed by the BS in biomedical engineering, the BSOM, and the dental school. Future growth or expansion will be funded based on university and UNC-GA models as is currently the case.

The faculty associated with the proposed program will mentor graduate research using the equipment and facilities described below. This equipment, and the associated laboratory space, are already in place, and are actively used in current research.

The Department of Engineering supports a number of laboratories across several engineering disciplines.Within biomedical engineering, there are several lab spaces housing a variety of equipment. Room 350 (1200 sq. ft.) in the Science and Technology Building houses a complement of advanced electronics fabrication and test equipment. This equipment includes an MSO4054B 500 MHz mixed-signal oscilloscope; a Tektronix AFG3022B 25 MHz, dual-output arbitrary waveform generator; Tektronix P5205 high-voltage differential probe and ADA400 differential preamplifier; a TCP0030 current probe; and an Agilent 34410A digital multimeter. Room 243 in the Science and Technology Building is predominantly a teaching laboratory space. Within that space are several fully stocked electronics test benches, including Agilent E3631A triple-output power supplies; Agilent 34410A digital multimeters; Agilent 33220A, 20 MHz arbitrary waveform generators; and Agilent 5000 series oscilloscopes.

Additional high-end electronic measurement and test equipment is available in the Biosensors Research Lab. Specific equipment includes Agilent MSO6034A oscilloscope, 1682A logic analyzer, 6622A power supply, 34410A digital multimeter, 33220A function generator, Cadence P-SPICE, Electronics Workbench Multisim, soldering stations, wireless communication modules (Bluetooth, Zigbee) and development tools, medical sensors, personal computers, LPKF print circuit board rapid-prototype machine, Microchip Integrated Development Tools, software licenses for LabVIEW, MATLAB, Solidworks, and NI-ELVIS.

The Bioprocess Engineering Laboratory (1100 sq. ft.) is a teaching and predominantly research laboratory, located in room 131 of the Science and Technology Building.  Current courses in upstream bioprocessing (wet-lab techniques, bacterial cultures in both shaker flasks and benchtop bioreactors, and cell harvesting) and downstream processing (distillation, extraction, affinity chromatography) are taught in this laboratory each semester.  The major equipment housed in the laboratory that is available for teaching and research includes two 5L and two 2L benchtop bioreactors (Sartorius BioStat Aplus), GE AKTA Purifier system, centrifuge (Beckman Coulter Avanti J-E), top loading autoclave for the bioreactors (Hirayama HICLAVE), front loading autoclave (Tuttnauer Brinkmann 2540E), table-top shaker/incubator, pH meter (Thermo Orions Star series), sonic dismembrator (Fisher Model 100), spectrophotometer (Perkin Elmer Lambda 45 UV/VIS), bath sonicator, analytical balance (Mettler Toledo), stir/hot plates, lyophilizer (Labconco Freeze Zone 4.5), luminometer (Promega Glomax 20/20), fluorometer (Promega, Modulus), three-door chromatography

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cabinet, protein and DNA electrophoresis equipment, thermal cycler, and small equipment and tools to conduct molecular biology research (micropipettes, table-top centrifuge, etc.).

In addition, this facility houses a TA Instruments AR-2000 stress-controlled Rheometer, an Olympus BX-51 reflected light microscope with a 12MP digital camera and bright field/dark field/fluorescence, and a ramé-hart Model 250 Standard Contact Angle Goniometer/Tensiometer for contact angle and surface tension measurements.

The Engineering Department maintains a variety of industrial quality fabrication and mechanical engineering instrumentation equipment, including (but not limited to) lathes, milling machines, a variety of welders, a band saw, workbenches, vices, a wide assortment of hand tools, a phototachometer, an extensometer, a shear test fixture, durometers, and hardness testers.

East Carolina University maintains and supports shared research facilities and services.Shared equipment available on ECU’s main campus includes an Accelerator Laboratory, Acoustic Laboratory, Biomedical Laser Laboratory, Biomedical Optics Laboratory, Genomics and Bioinformatics Laboratory, High Performance Computing Facility, Nuclear Magnetic Resonance Spectroscopy Laboratory and Mass Spectrometry Facility.

The computing needs of biomedical engineering graduate students will be supported by the department, High performance computing laboratory and Information Technology and Computing Services (ITCS).

The laboratories listed above, and any office space, are equipped with the computers needed to perform data analysis or other research related tasks. ITCS supports additional student computing needs through two unique services: high performance computing and the Virtual Computing Lab. The high performance computing capabilities offered by ITCS are optimized for solving some of the advanced computational problems that arise in engineering research. The Virtual Computing Lab, located at NC State University, provides remote access to a variety of advanced software packages. ITCS provides this access through ECU’s network.

In addition, the College of Technology and Computer Science will provide an array of support that will include software, hardware, and technical services support. Examples of support include desktops on demand, virtual servers on demand and network attached storage space. In addition, TECS technical services can provide support for cluster computing and remote display of graphically intensive applications.

Research facilities supported by the Brody School of Medicine include:Major laboratory equipment is available in the Brody Medical Sciences Building (3S-16, 400 sq. ft), including a laminar flow hood, chemical hood, three CO2 water-jacketed incubators, centrifuge with rotors, laboratory refrigerator and freezer; an inverted microscope, upright microscope and dissecting microscope; distilled water source, balance, and pH meter.

The Brody School of Medicine also offers core facilities to support east and west campus research efforts. These facilities include a flow cytometry/confocal microscopy facility, an electron microscope lab, a histology lab, and a phosphor-imaging/fluorescence imaging lab. Shared resources include (but are not limited to) centrifuges, electrophoresis equipment, various imaging systems, chromatography systems, an ultrasound machine, microscopes, and spectrophotometers.

The Tissue Culture Facility located in room 279 Warren Life Science Building (LSB 279, 800 sq ft) offers additional lab space. Major equipment includes four bench top work areas with adjacent laminar flow hoods, one chemical hood, two CO2 water-jacketed incubators, tabletop centrifuge with rotors, laboratory refrigerator, two laboratory freezers (-20° C, -80° C), a Dewar liquid nitrogen cell storage system, inverted and upright light microscopes, a digital camera with C-mount, and distilled water source.

● How will assignment of this space to the proposed program impact existing programs?The spaces proposed are currently available for use by our faculty and will not impact existing program utilization of the space.

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● Describe additional facilities or specialized equipment that would be needed over the next five years.With the growth of the program additional space will be needed for graduate student desk space and for new faculty members.

● Describe current holdings in library resources in the proposed program and projected library resources needed to support the proposed program.

Current journal subscriptions and books are sufficient to start the proposed program including the Journal of Biomechanics, the Journal of Magnetic Resonance Imaging, Medical and Biological Engineering and Computing, several IEEE Transactions series, and the Journal of Neural Engineering. A few additional subscriptions (for example, Journal of Biomechanical Engineering) may need to be added over the first five years.

● Provide e-mail verification of consultation with Office of Space Management about the feasibility of new or additional space needs for the proposed program.

Please see attached email.

Personnel● What additional personnel would be needed to make the proposed program successful for growth and

development over a five-year period? - Faculty – 1 additional position in Year 3- Two post-doctoral associates, one research technician, and one additional position to oversee

research and graduate lab courses- Graduate assistants – 10 by Year 5- Other staff – 0.5 additional position to oversee graduate program paperwork

● What will be needed to recruit such individuals and what is the recruitment market like? To recruit the one additional faculty member a start-up package will be needed to attract highly qualified individuals. Graduate assistantships will be needed to attract quality graduate students. As biomedical engineering is a specialized field most industry jobs require at least an MS degree illustrating a high demand for the program.

Part Four: Assessing Financial Resources to Support the Program

● Describe existing financial resources to be devoted to the proposed program.The Department of Engineering currently has 17.5 FTE faculty positions, with seven of the current faculty supporting the biomedical engineering concentration indirectly. Allocation of two additional positions has been made for the coming year, and a portion of 1.5 FTE of those positions will support biomedical engineering. Faculty resources are sufficient for initiation of the program.

● Describe what additional financial resources would be needed over the next five years and their proposed sources of funding.

- Ten graduate assistantships at $15,000 each- Five out of state tuition remissions, phased in over five years- One additional faculty member in Year 3 of the MS Program- Two postdoctoral associates to support the research and educational objectives of the program

● What new financial resources will come to the university based on the projected increase in enrollment?At our projected enrollment of 25 MS students, taking 18 credits of engineering courses during the course of their program, the additional student credit hours will justify one additional faculty position. In addition, the students will be involved in performance of externally-funded research programs, which will result in additional funding for ECU, along with indirect costs. Additional scholarship will also result from the program.

We believe there is considerable potential for patents to result from the research and development conducted as part of this program. As an example, Dr. Jason Yao of Engineering and Dr. Greg Givens of

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Communication Sciences and Disorders have filed a patent for “Internet-based Multi-user Diagnostic Hearing Assessment Systems Having Client-server Architecture with User-based Access Levels for Secure Data Exchange,” provisional patent, 2009-2010; currently filing PCT (Patent Cooperation Treaty) to protect intellectual property rights worldwide. The university share of the royalties would generate financial resources.

● Will the program students contribute to the financing of the program through teaching, research, and clinical practice?

The students will contribute by serving as teaching assistants in the undergraduate program and performing externally funded research.

● What are your plans for the program if the financial resources anticipated for the program (enrollment, external support, etc.) are 25% lower and 50% lower than expected?

Considering the current strength of the program and the growth in the related networking jobs forecasted by the Bureau of Labor Statistics, a decline in program enrollment is unlikely. Current employment and labor projections in biomedical engineering related areas are very strong. If the decision was made to cut resources at the University or College level, possibly by refusing the graduate assistantships or the additional faculty line in Year 3, the program would still be viable. Reduction of the number of assistantships would effectively reduce the “quality” of the students in the program since the best students would find assistantships at other universities and our program would be forced to admit students who are not able to find assistantships elsewhere. If the additional faculty position were refused, the projected size of the program might be reduced. In addition, the potential for research efforts in bioengineering would be reduced overall if faculty numbers are lower.

Part Five: Assessing External Support and Collaboration

● List of active grants/contracts specifically related to the proposed program.

Award No. TitleFaculty Member Sponsor Award

Primary Biomedical Engineering Faculty

R01-HL091348 

Mechanisms for stem cell differentiation into cardiac myocytes (co-investigation with Duke University)

Muller-Borer (co-

investigator)

National Heart, Lung, and Blood Institute

$357,612

R01-HL081720 

NO-independent cGMP regulation of vascular remodeling

Muller-Borer (co-

investigator)

National Heart, Lung, and Blood Institute

$252,325

 Assessment of myocardial cellular transplantation via multiple delivery modes

Muller-Borer (Co-PI)

The Eastern Carolina

Cardiovascular Institute &

BSOM

$125,000

 

Role of thymosin B4 in stem cell engraftment and myocardial tissue regeneration

Muller-Borer (PI)

East Carolina University Division of

Research and Graduate Studies

$40,000

  Effects of cardiopulmonary bypass

Muller-Borer (co-

East Carolina University $25,000

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on adult stem cell transplantation investigator)

Division of Research and

Graduate Studies

Associated Engineering Faculty

A11-0048-001

Engineering photoreceptor-controlled aggregation and disaggregation of nanoparticles

Limberis (PI)NC

Biotechnology Center

$75,000

A10-0176-001

Integration of hands-on short course into a bioprocess engineering curriculum

Williams (PI)NC

Biotechnology Center

$40,480

A10-0043-0001

Portable cyber-laboratories: virtual instruments and affordable prototyping kits to enhance learning and improve access to electrical engineering education

Yao (PI) NSF $88,100

A08-0053-0001

Design and development of educational modules for bioprocess engineering

Williams (PI) NSF $136,480

● Describe existing collaborative efforts related to the proposed program with community or state agencies, other institutions of higher education, federal laboratories or agencies, national centers, or other external organizations.

The Engineering Department maintains a collaborative relationship with the following industry partners, who are members of the Engineering Advisory Board:

- Becton Dickenson Medical- Pitt County Memorial Hospital- Glaxo SmithKline, Inc.- Pharmaceutical Calibrations and Instrumentation- Pioneer Surgical Orthobiologic, Inc.- DSM Pharmaceutical Products, Inc.- DSM-Dyneema, LLC- Triangle Biosystems Inc.- Wyeth Vaccines- NC Biotechnology Center- Pfizer- NASA Langley Research Center- NAACO Materials Handling Group- PCS Phosphate- Metrics, Inc.- Avoca

The Engineering Advisory Board is comprised of approximately 40 members from industry, consulting firms, academia, and government laboratories. The board meets twice per year to review current and planned programs, review student achievement, and to provide guidance on future directions of the

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program. The board is extremely active, and the department chair maintains contact with the board throughout the year. A number of these organizations participate in the department’s Senior Capstone Design Project, and offer collaborations for graduate level research projects. The faculty is continuously pursuing industry and government partners. A new partner for 2011 is the Centers for Disease Control who is sponsoring a Senior Capstone Project.

● How do you plan to use external funding to support the proposed program? To what agencies or programs would proposals be submitted and with what timeframe?

The following external agencies support academic biomedical engineering research, both nationally and regionally:

- The National Institutes of Health. One of the stated goals of the NIH is to foster creative discoveries, innovative research strategies, and their applications as a basis for protecting and improving health. The NIH realizes this goal by supporting a wide range of research activities, through the 27 Institutes and centers that comprise this federal organization. Specific institutes that are pertinent to the proposed program include the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of General Medical Sciences (NIGMS), and the National Heart, Lung, and Blood Institute (NHLBI).

The NIH also funds research projects at less-established research universities through several grant mechanisms. One such mechanism is the Academic Research Enhancement Award (AREA) grant, which is specifically designed to stimulate biomedical research at institutions that provide baccalaureate and advanced degrees.

- The National Science Foundation. A well-established federal agency created “to promote the progress of science; to advance the national health, prosperity and welfare; to secure the national defense…” This organization has a long-standing history as a major source of federal funding for a wide assortment of cutting-edge STEM research.

- Department of Defense. The DoD provides a number of grant mechanisms through the Defense Advanced Research Projects Agency (DARPA), Office of Naval Research (ONR), Air Force Office of Scientific Research (OSR), and the Multidisciplinary University Research Initiative (MURI). A popular graduate fellowship program offered by the DoD, is the National Defense Science and Engineering Graduate Fellowship. This program provides three years of support for studies in biosciences, electrical engineering, and cognitive, neural, and behavioral sciences.

- The North Carolina Biotechnology Center. The NC Biotech center is a state-funded, privately held non-profit organization dedicated entirely to biotechnology development. The mission of this center is to provide long-term economic and societal benefits to North Carolina by supporting biotechnology research, commercialization, collaboration, and education. The NCBC funds biotechnology research in areas such as nanobiotechnology and combination medical devices. The center also funds multidisciplinary research, for projects consisting of scientists from at least three distinct fields.

The engineering faculty supporting the proposed program has experience applying for, and receiving, external funding from the above organizations. The stated goals of each grant agency, and the funding programs offered, align with the research background of the faculty. Specifically, the proposed biomedical engineering graduate program will foster research in the following areas: neural and cardiac electrophysiology, cardiac stem cell therapies, computational hemodynamics, blood flow analysis using MRI, medical imaging, and medical device design and MRI compatibility.

Research efforts in these areas are either ongoing through existing grants (listed above), or are already in development. Faculty members in the proposed program are currently preparing competitive grant applications for initial submission in the 2010-2011 and 2011-2012 academic years.

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As mentioned in the personnel requirements, the program can be started with current faculty personnel and resources, however to initiate research momentum, funding for graduate assistants may be needed during the start-up period. This will allow for preliminary research to be conducted preparing the core engineering and collaborating faculty to compete for external funding.

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Faculty Information SheetName: Odis Hayden Griffin, Jr., Ph.D., P.E.1. Rank: Professor and Chair, Department of Engineering at East Carolina University

2. Degrees: Virginia Polytechnic Institute & State University, Blacksburg, Virginia

Doctor of Philosophy in Engineering Mechanics, June, 1980. Course work primarily in area of solid mechanics. Dissertation “Three Dimensional Inelastic Finite Element Analysis of Laminated Composites.” Use of finite element method with a modified Hill-type yield criterion and flow rule to study interlaminar stresses in laminates subject to thermal and mechanical loading.

Texas Tech University, Lubbock, TexasMaster of Science in Mechanical Engineering, May 1971. Course work primarily in thermodynamics and heat transfer. Thesis, “A New Theory of Protoplasmic Streaming.” Application of nonequilibrium thermodynamic principles to living cells.

Bachelor of Science in Mechanical Engineering, August 1970. Course work in thermodynamics, heat transfer, machine design, fluid dynamics, strength of materials, and metallurgy.

3.Teaching Experience related to proposed degree (with emphasis on the past five years)Workload assignment: 15% teaching, 85% administrative

July 2010 to present, Professor and Chair, Department of Engineering, East Carolina University, Greenville, North Carolina 27858

Leading the faculty of the East Carolina University Department of Engineering. Serve as chief administrative officer, reporting to the Dean of the College, responsible for department’s resources, staff, and budgets. Provide leadership for the department in accomplishing departmental mission and setting and achieving goals. Promote excellence in teaching and advising, scholarship, research productivity, economic development, and professional service. Serve as principal advocate for the department within the College, serving on the Administrative Council. Ensure proper application of tenure and promotion policies set forth in the East Carolina University Faculty Manual. Conduct annual faculty activity planning and evaluation. Working to evaluate possible new concentrations in the BS in Engineering program and working with a faculty group to develop a MS in biomedical engineering degree program.

May 2004 – June 2010, Professor and Head, Department of Engineering Education (departmental name change), College of Engineering, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0218

Planned and led changes in the department from a primarily teaching-only, freshman engineering program to a degree-granting, research-oriented department, increasing external research funding from near zero in 2003 to several million dollars at the present time, including three NSF CAREER Awards (Borrego, Paretti, and Johri) and one PECASE (Borrego). Added new faculty in the area of academic assessment, technical communications, engineering design, and learning sciences. Led and participated in research proposals in the area of engineering education. Diversified the faculty from all white males (1997) to a department in which half (9 of 18) of the faculty are women, with good ethnic and disciplinary diversity as well. Tenure outcomes for faculty hired since 1997 were good, and newer hires are progressing well toward tenure due to continuous attention to faculty development, assessment, and feedback.

Beginning in 2004, I led the effort to create a graduate program from scratch, culminating in a Ph.D. in Engineering Education, which accepted students in January 2008 and currently has 15 Ph.D. candidates. Have developed and taught or co-taught five new engineering education graduate courses: “Preparing for the Engineering Professoriate,” “Teaching Engineering,” “Practicum in the Engineering Classroom,” “Training System Design,” and “Foundations of Engineering Education.” Led the development of a Graduate Certificate in Engineering Education which is in place and has approximately 20 students

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participating. Presented the new courses and degree programs at all committees and commissions reviewing it for approval and also presented at the Board of Visitors and State Council of Higher Education for Virginia. Served as Graduate Program Director from January 2008 to February 2009. Presented information on engineering education and our graduate program to a Virginia General Assembly subcommittee considering creation of K-12 level standards of learning and other programs in Virginia public schools.

In 2006 my department was one of two university departments designated as a University Exemplary Department for developing and sustaining innovative and effective departmental approaches to introductory courses at the graduate and undergraduate levels. These awards are highly competitive and result in a $20,000 award to the department. As a group the faculty decided to spend the award on new office furniture as we moved into newly renovated space that I spent approximately two years working with the Provost and the Dean to obtain for the department. I am currently on the team that is providing design information for a new engineering building.

Worked with college development office personnel to gain gifts for laboratory renovation, facility maintenance, support for academic programs, and overall department support from both alumni and industry. Have obtained gifts in the form of cash, stock, hardware, and shop equipment.

Overall management of departmental budget of approximately $2M. In 11 years as department head, was never over budget, even though considerable resources were directed toward development of new courses, supporting the success of new faculty, creation of spaces for hands-on learning, and development of a PhD program. Department typically teaches 7,000-8,000 student credit hours annually.

Serving on the Program Assessment Committee of the Advisory Board for the University of Texas at El Paso College of Engineering. Regularly review papers for JEE, AEE, ASEE, ASME, iNEER. Served on NSF grant review panels twice for CCLI grants. Served on numerous College and University level committees. Most recently served on search committees for Director of Academic Assessment, Assistant Director of Academic Assessment, and Director of the Center for Excellence in Undergraduate Teaching. Served on the VT-Science Museum of Western Virginia Partnership Task Force and the Organizing Committee for the Governor’s Conference on STEM Education.

August 1997 – May 2004, Professor and Director, Division of Engineering Fundamentals (renamed as Department of Engineering Education in 2004), College of Engineering, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0218

In addition to regular duties of a faculty member in the College of Engineering, oversee the efforts of the Engineering Fundamentals faculty and staff. The faculty currently has 14 members, including two part-time professional advisors. There are three full-time classified staff. Managing the Joseph F. Ware, Jr. Advanced Engineering Laboratory, an undergraduate student project laboratory with projects spanning numerous departments in the College of Engineering, Pamplin College of Business, and the College of Arts & Sciences. Leading the review and revision of the freshman engineering curriculum. Teaching courses in Engineering Fundamentals (problem solving, programming, introduction to design, and engineering graphics) and Mechanical Engineering (Advised Mini Baja Team, which is the capstone design project for some students, from August 1995 to May 2001).

Instituted policies for common syllabi, common tests, and common final exams in introductory engineering courses. Currently responsible for managing enrollments, assigning faculty teaching loads, and overseeing development of EF teaching schedule. Have encouraged, with success, EF faculty to write grant proposals, leading to several faculty who buy out of courses with project money. Scholarly production is also increasing steadily.

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July 1993 – August 1997, Associate Dean for Academic Affairs, College of Engineering, July 1994 – August 1997, Professor of Engineering Science & Mechanics, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0217

In addition to regular duties of a faculty member in the College of Engineering, have responsibility for the undergraduate program of the College. Responsible for preparing ABET materials for College and coordinating departmental packages for Fall 1995 visit, with highly successful outcome. Serve on numerous College- and University-level task forces, commissions, and committees. Responsible for assembling departmental offerings for summer school and overseeing College summer school budget ($725K-$825K). Advise students on major changes, approve exceptions to University and College policies for undergraduates. Working on evaluation of curriculum and curriculum reform including course overlap between departments, cross-listing common courses. Chairing college-level committee assigned to review the undergraduate curriculum and revise from the beginning courses. Work with College Curriculum Committee for review of all proposed course modifications and inclusion of Engineering courses in the University Core Curriculum. Visit community colleges to recruit students, assist with in-house recruitment and retention programs. Proposed a new category for students wanting engineering who had previously been offered a general studies curriculum so that they are now students in Engineering and are able to take Engineering courses without difficulty. The first class of these students was admitted in the Fall 1994, and we are currently evaluating their performance. General response from students and parents has been overwhelmingly positive. Work with Admissions, Provost’s Office, Registrar’s Office, and other Associate Deans across the University in dealing with student admissions, appeals for academic exceptions, and resolving graduation problems.

During the period 1996-1998 I was the leader of the team that designed, oversaw the renovation, and directed the operations of the Joseph F. Ware, Jr. Advanced Engineering Laboratory. The Ware Lab, as it is popularly known, is one of a few such facilities in the country dedicated to undergraduate engineering projects. The Ware Lab (http://www.eng.vt.edu/warelab/) is a 10,000 square foot facility with a machine shop, welding shop, design studio, and work bays for student projects. Opened in September 1998, the Ware Lab has been a great success.

Courses taught include: ESM 1000, Statics; ESM 4044, Mechanics of Composite Materials; ESM 4734/AOE 4024, Introduction to the Finite Element Method; ESM 3074 (now 2074), Computational Methods; ESM 2004, Mechanics of Deformable Bodies; ESM 5184, Special Study (Scientific Visual Analysis); ESM 5734, Introduction to the Finite Element Method; ESM 6734, Finite Element Method; ME 4014, Design Studies in Mechanical Engineering (Mini-Baja car project); ME 4016, Engineering Design and Project (Mini-Baja car project); EF 1005, Introduction to Engineering. Have modernized several courses, including Computational Methods. To date have advised ten M.S. theses and seven Ph.D. dissertations.

September 1985 - June 1994, Associate Professor of Engineering Science & Mechanics, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0219

Involved in teaching, advising students, and performing research in mechanics of composite materials. Primary research interests include development of analytical and design tools for composites, including laminates and textile composites. Current efforts include designing crashworthy composite airframe components, analysis techniques for textile composites, and developing design and analysis tools for smart, damage tolerant/compensating composite structural components.

Co-investigator, NASA-Virginia Tech Composites Program, an ongoing program with NASA Langley Research Center. Primary activity was with Impact Dynamics Branch, involving analytical and experimental work in the dynamic response and failure of composite frames such as those used in aircraft primary structures and with the Mechanics of Materials Branch, developing analytical models for predicting stiffness, strength, and residual strength in textile composites.

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Co-investigator of a University Research Initiative on mechanics of smart materials and structures, funded by the Army Research Office. Responsibility for developing models for designing active control mechanisms for detecting and preventing growth of delaminations in composite laminates.

Graduate student supervisory experience (theses/dissertations):10 M.S. (with thesis) graduates, 7 Ph.D. completed.

Mark D. Sensmeier (co-advised with E. R. Johnson of AOE), M.S. Thesis, “Static and Dynamic Large Deflection Response of Graphite-Epoxy Beams,” June, 1987.

Marco A. Vidussoni, M.S. Thesis, “Global-Local Finite Element Analysis of Laminated Composites,” July 1988.

Gajanan V. Gandhe, M.S. Thesis, “Impact Response of Interleaved Composite Materials,” November 1988.

Shih Y. Lin, M.S. Thesis, “Investigation of the Use of Composite Materials in Highway Bridge Deck Modules,” December 1988.

David E. Bowles, Ph.D., “Micromechanics Analysis of Space Simulated Thermal Deformations and Stresses in Continuous Fiber Reinforced Composites,” December, 1989.

Danniella M. Thompson, M.S. Thesis, “Two-Dimensional to Three-Dimensional Global/Local Finite Element Analysis of Laminated Composites in Compression,” May 1990.

Dong K. Shin (co-advised with Z. Gurdal of ESM), Ph.D., “Minimum-Weight Design of Symmetrically Laminated Composite Plates for Postbuckling Performance Under In-plane Compression Loads,” September 1990.

Nicole Breivik (co-advised with Z. Gurdal of ESM), M.S. Thesis, “Compression of Thick Laminated Composite Beams with Initial Impact-Like Damage,” February 1992.

David H. Mollenhauer, M.S. Thesis, “Induced Strain of Actuation of Surface Bonded and Embedded Piezoceramic Patches,” April 1992.

Seshu R. Yalamanchili (co-advised with M. W. Hyer of ESM), M.S. Thesis, “Response of Multiple Fastener Composite Joints: Numerical and Experimental Results,” May 1992.

Jae Lee (co-advised with Z. Gurdal of ESM), Ph.D., “Vibration, Buckling and Postbuckling of Laminated Composites with Delaminations,” May 1992.

Elissa E. Carapella (co-advised with M. W. Hyer of ESM), M.S. Thesis, “Micromechanics of Crenulated Fibers in Carbon/Carbon Composites,” October 1992.

Su-Yuen Hsu, Ph.D., “Finite Element Micromechanics Modeling of Inelastic Deformation of Unidirectionally Fiber-Reinforced Composites,” July 1992.

Lucie M. H. Parietti, M.S. Thesis, “Micromechanical Finite Element Model for Constitutive Elastoplastic Analysis of Unidirectional Fiber-Reinforced Composites,” August 1994.

Eduardo Moas, Jr., Ph.D., “Progressive Failure Analysis of Laminated Composite Structures,” April 1996.

Edward H. Glaessgen, Ph.D., “Modeling of Textile Based Composite Materials, June 1996. Mark D. Sensmeier, Ph.D., “Optimum Crashworthiness Design of Grid-Stiffened Composite

Fuselage Structures,” September 1996.Served on advisory committees of numerous students in Departments of Engineering Science and Mechanics, Aerospace and Ocean Engineering, Civil Engineering, and Mechanical Engineering. Served on the examining committee for one MS student in Technology Education. Serving on PhD committees of one student in Technology Education, one student in Computer Engineering, and several students in Engineering Education.

Recent and Current Graduate Student AdvisingServed on Ph.D. advisory committees of Jennifer Mullin (Ph.D., Engineering Education, Virginia Tech, May 2010) and Ricky Castles (Ph.D., Computer Engineering, Virginia Tech, May 2010). Currently serving on Ph.D. committee of Parhum Delgoshaei (Ph.D. Candidate, Engineering Education, Virginia Tech, anticipated completion May 2012).

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4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years):a. Publications/Scholarly Activity related to proposed degree:

Benson, Lisa, Kurt Becker, Hayden Griffin, and Karl Smith, 2010. “Engineering Education: Departments, Degrees and Directions,” International Journal of Engineering Education, Special Edition on Applications of Engineering Education Research, Vol 5.

Lohani, V., Castles, R., Lo, J., and Griffin, H., 2008. “Tablet PC Applications in a Large Engineering Program,” Computers in Education Journal, Vol XVIII, No. 1, April-June 2008, pp 52-63.

Snook, J., Lohani, V.K., Lo, J.L., Sirvole, K., Mullin, J.S., Kaeli, J.K., and Griffin, O.H., “Incorporation of a 3-D Interactive Graphics Programming Language into an Introductory Engineering Course,” Computers in Education Journal, Vol XVI, No. 3, July-September 2006, pp 63-72.

Lee, J., Gurdal, Z., and Griffin, O. H., Jr., “Buckling and Postbuckling of Circular Plates Containing Concentric Penny-Shaped Delaminations,” Computers & Structures, vol. 58, No. 5, 1996, pp. 1045-1054.

S. Y. Hsu and O. H. Griffin, Jr., “Algorithmic tangent matrix approach for mixed hardening model of endochronic plasticity,” Computer Methods in Applied Mechanics and Engineering, Vol 133, 1996, pp 1-14.

E. H. Glaessgen, C. M. Pastore, O. H. Griffin, Jr., and A. Birger, “Geometrical and finite element modeling of textile composites,” Composites: Part B, Vol 27B, No 1, 1996, pp 43-50.

E. H. Glaessgen and O. H. Griffin, Jr., “Micromechanical Analysis of Thermal Response in Textile-Based Composites,” AIAA Progress in Aeronautics and Astronautics, Earl A. Thornton, Editor, Volume 168, 1995, pp 204-217.

J. Lee, Z. Gurdal, and O. H. Griffin, Jr. “Postbuckling of Laminated Composites with Delaminations,” AIAA Journal, Vol 33, No 10, October 1995, pp 1963-1970.

D. Cohen, M. W. Hyer, O. H. Griffin, Jr., S. R. Yalamanchili, M. J. Shuart, and C. Prasad, “Failure Criterion for Thick Multi-Fastener Graphite-Epoxy Composite Joints,” Journal of Composites Technology and Research, Vol 17, No 3, 1995, pp 237-248.

L. M. Parietti, S. Y. Hsu, and O. H. Griffin, Jr., “Mini Constitutive Finite Element Model for Plastic Response of Unidirectional Fiber Composites,” Computers and Structures, Vol 55, No 3, May 1995, pp 463-470.

E. Moas, R. L. Boitnott, and O. H. Griffin, Jr., “An Analytical and Experimental Investigation of the Response of Curved, Composite Frame/Skin Specimens,” Journal of the American Helicopter Society, July, 1994, pp. 58-66.

J. Lee, R. T. Haftka, O. H. Griffin, Jr., L. T. Watson, and M. D. Sensmeier, “Detecting Delaminations in a Composite Beam using Anti-optimization,” Structural Optimization, Vol 8 (2/3), October 1994, pp 93-100.

E. E. Carapella, M. W. Hyer, O. H. Griffin, Jr., and H. G. Maahs, “Micromechanics of Crenulated Fibers,” Journal of Composite Materials, Vol 28, No 14, 1994, pp 1322-1346.

D. H. Mollenhauer and O. H. Griffin, Jr., “Induced Strain of Actuation of Surface Bonded Piezoceramic Patches: A Numerical and Experimental Study,” Journal of Intelligent Material Systems and Structures, Vol 5, No 3, May 1994, pp 355-362.

O. H. Griffin, Jr., M. W. Hyer, S. R. Yalamanchili, M. J. Shuart, C. B. Prasad and D. Cohen, “Analysis of Multi-Fastener Composite Joints,” Journal of Spacecraft and Rockets, Vol 31, No 2, March-April 1994, pp 278-284.

David H. Mollenhauer, Danniella Muheim Thompson, and O. Hayden Griffin, Jr., “Finite Element Analysis of Smart Structures,” Advances in Engineering Software, Vol 17, No 1, 1993, pp 7-12.

N. L. Breivik, Z. Gurdal, and O. H. Griffin, Jr., “Compression of Laminated Composite Beams with Initial Damage,” Journal of Reinforced Plastics and Composites, Vol 12, No 7, July 1993, pp 813-824.

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D. M. Thompson and O. H. Griffin, Jr., “Finite Element Predictions of Active Buckling Control of Stiffened Panels,” Journal of Intelligent Material Systems and Structures, Vol 4, No 2, April, 1993, pp 243-247.

O. H. Griffin, Jr., E. R. Johnson, and M. D. Sensmeier, “Nonlinear Response of Graphite-Epoxy Wide Columns Subject to Eccentric Load,” Journal of Applied Mechanics, Vol 60, No 1, March 1993, pp 101-108.

D. K. Shin, O. H. Griffin, Jr., and Z. Gurdal, “Postbuckling Response of Laminated Plates Under Uniaxial Compression,” International Journal of Nonlinear Mechanics, Vol 28, No 1, Jan 1993, pp 95-115.

S. Y. Hsu and O. H. Griffin, Jr., “On Stability and Efficiency of Numerical Integration of Endochronic Constitutive Equations,” Computers and Structures, Vol. 44, No. 3, 1992, pp 657-665.

D. M. Thompson and O. H. Griffin, Jr., “Verification of a 2-D to 3-D Global/Local Finite Element Method for Symmetric Laminates,” Journal of Reinforced Plastics and Composites, Vol 11, No 8, August 1992, pp 910-931.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “Minimum-Weight Design of Laminated Composite Plates for Postbuckling Performance,” Applied Mechanics Reviews, Vol 44, No 11, part 2, Nov 1991, pp S219-S231.

D. E. Bowles and O. H. Griffin, Jr. “Micromechanics Analysis of Space Simulated Thermal Stresses in Composites. Part II: Multidirectional Laminates and Failure Predictions,” Journal of Reinforced Plastics and Composites, Vol 10, No 5, September 1991, pp 522-539.

D. E. Bowles and O. H. Griffin, Jr. “Micromechanics Analysis of Space Simulated Thermal Stresses in Composites. Part I: Theory and Unidirectional Laminates,” Journal of Reinforced Plastics and Composites, Vol 10, No 5, September 1991, pp 504-521.

N. F. Knight, Jr., J. B. Ransom, O. H. Griffin, Jr., and D. Muheim Thompson, “Global/Local Methods Research Using a Common Structural Analysis Framework,” Finite Elements in Analysis and Design, Vol 9, No 2, June 1991, pp 91-112.

S. S. Lane, R. H. Moore, H. P. Groger, G. V. Gandhe, and O. H. Griffin, Jr., “Eddy Current Inspection of Graphite/Epoxy Laminates,” Journal of Reinforced Plastics and Composites, Vol 10, No 2, March 1991, pp 158-166.

S. Y. Hsu, S. K. Jain, and O. Hayden Griffin, Jr., “Verification of Endochronic Theory for Nonproportional Loading Paths,” ASCE Journal of Engineering Mechanics, Vol 117, No 1, January 1991, pp 110-131.

D. Muheim Thompson, O. H. Griffin, Jr., and M. A. Vidussoni, “Global/Local Finite Element Analysis of Cross-Ply Composite Laminates,” Journal of Composites Technology and Research, Vol 12, No 4, December 1990, pp 209-216.

D. Muheim Thompson and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Cross-ply Composite Laminates,” Journal of Reinforced Plastics and Composites, Vol 9, No 5, September 1990, pp 492-502.

J. L. Sevart, O. H. Griffin, Jr., Z. Gurdal, and G. A. Warner, “Flammability and Toxicity of Composite Materials for Marine Vehicles,” Naval Engineers Journal, Vol 102, No 4, September, 1990, pp 45-54.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “A Penalty Approach for Nonlinear Optimization with Discrete Design Variables,” Engineering Optimization, Vol 16, No 1, July, 1990, pp 29-42.

G. V. Gandhe and O. H. Griffin, Jr., “Post-Impact Characterization of Interleaved Composite Materials,” SAMPE Quarterly, Vol 20, No 4, July 1989, pp 55-58.

Mark D. Sensmeier, O. Hayden Griffin, Jr., and Eric R. Johnson, “Effect of Axial Impact on the Static Flexure of Graphite/Epoxy Beams,” Journal of Reinforced Plastics and Composites, Vol 8, No 3, May 1989, pp 299-309.

O. Hayden Griffin, Jr., “Three Dimensional Thermal Stresses in Angle-Ply Composite Laminates,” Journal of Composite Materials, Vol 22, No 1, January 1988, pp 53-70.

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O. H. Griffin, Jr., “The Use of Proper Shear Moduli in the Analysis of Composite Materials,” Composites Technology Review, Vol 6, No 1, Spring 1984, pp 22-24.

O. H. Griffin, Jr. and J. C. Roberts, “Numerical/Experimental Correlation of Three Dimensional Thermal Stress Distributions in Graphite/Epoxy Laminates,” Journal of Composite Materials, Vol 17, Nov 1983, pp 539-548.

J. C. Roberts and O. H. Griffin, Jr., “Numerical/Experimental Heat Transfer in Dry Sliding of Polymeric Composites,” ASLE Transactions, Vol 26, No 4, 1983, pp 493-500.

O. H. Griffin, Jr. “Three Dimensional Curing Stresses in Symmetric Cross-ply Laminates with Temperature Dependent Properties,” Journal of Composite Materials, Vol 17, Sept 1983, pp 449-463.

O. H. Griffin, Jr. and C. R. Wilson, “Finite Element Analysis on a Microprocessor Based Personal Workstation,” Computers and Structures, Vol 17, No 4, 1983, pp 617-619.

O. H. Griffin, Jr., “Evaluation of Finite Element Software Packages for Stress Analysis of Laminated Composites,” Composites Technology Review, Vol 4, No 4, Winter 1982, p 136.

O. H. Griffin, Jr., M. P. Kamat, and C. T. Herakovich, “Three Dimensional Inelastic Finite Element Analysis of Laminated Composites,” Journal of Composite Materials, Vol 15, Nov 1981, pp 543-560.

b. Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners): “A National Symposium to Develop and Present a Case for the Establishment of Engineering

Education Academic Programs (SEEAP),” NSF Engineering Education and Centers unsolicited proposal, Kurt Becker (Utah State), Kamyar Haghighi (Purdue), Esin Gulari (Clemson), Hayden Griffin (Virginia Tech), ($99,548 for 1 year)

“Building Connections Within the Engineering Education Research Community,” NSF Engineering Education and Centers unsolicited proposal, Hayden Griffin (PI), Lisa McNair, Jenny Lo, Lisa McNair, and Marie Paretti ($153,691 for 1 year)

“Building Connections Within the Engineering Education Research Community,” NSF Engineering Education and Centers unsolicited proposal, Hayden Griffin (PI), Lisa McNair, Marie Paretti, Aditya Johri, and Christopher Williams ($307,468 for 2 years)

“International Network for Engineering Studies Workshop #1: Engineers and Education,”, NSF Office of International Science & Engineering, Gary Downey, Joe Pitt, Hayden Griffin ($32,820)

In 1993-94, I was the Principal Investigator at VPI&SU of SUCCEED Coalition, an eight-university consortium funded by NSF to conduct engineering education research. As a part of this research, I was responsible for monitoring all of the VPI&SU projects, control of the $100,000 plus administrative budget, and had authority and responsibility for determination of how to use the six FTE’s (approximate value $330,000 per year) associated with SUCCEED. I passed the SUCCEED responsibility along to an assistant dean because the demands on my time were too much considering my responsibilities to the undergraduate program.

“Bridges for Engineering Education – Virginia Tech,” $100,000, National Science Foundation, 8/1/2004 – 7/31/2006. One of many faculty involved.

“The NASA-Virginia Tech Composites Program”NASA Langley Research Center1974 - 1997Total funding - 1986 - 1997 - $4,300,000 (approximate)Principal investigators:O. H. Griffin, Jr., Z. Gurdal, M. W. Hyer, E. R. Johnson, A. C. Loos, D. H. Morris

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My share of the responsibility was for planning and conducting a portion of the work done with the Landing and Impact Dynamics Branch, Mechanics of Materials Branch, Aircraft Structures Branch, and the Applied Materials Branch. In addition, I worked with the Program Director one year in reviewing student applications, and was involved in the management of the Program during the year when we had an Interim Director.My share of the project funding is as follows:1985 - 1986: $11,000, 1986 - 1987: $50,000, 1987 - 1988: $48,500, 1989: $58,500, 1990: $46,000, 1991: $108,000, 1992: $138,035, 1993: $104,895, 1994: $95,000, 1995: $50,000My portion of funding, 1985 - 1995 was $709,930.

“Smart Materials, Structures and Mathematical Issues for Active Damage Control”Army Research Office University Research InitiativeTotal funding - $400,000July 1, 1992 - June 30, 1994 (years 1 and 2 of three years)Principal Investigators: C. A. Rogers, H. H. Robertshaw, R. T. Haftka, and O. Hayden Griffin, Jr.The responsibility was equally divided between the four investigatorsMy share of the project funding for 92-93 was $100,000 ($79,909 directly, plus $20,091 in educational and visiting scholar programs) and for 93-94 was $65,000.

“Development and Verification of Global/Local Analysis Techniques for Laminated Composites”NASA Langley Research CenterJune 16, 1986 - December 31, 1992Total funding - $183,194I was totally responsible for this project. The total funding, $183,194, was my responsibility.

“Thick Composite Joint Failure Analysis”Hercules Aerospace CompanyTotal funding - $70,048April 20, 1989 - December 31, 1991Principal Investigators: M. W. Hyer and O. Hayden Griffin, Jr.The responsibility of this project was equally divided between myself and Dr. Hyer.My share of the project funding was $35,024.

“Design of Stiffened Composite Plates for Postbuckling Performance”Newport News Shipbuilding & Dry Dock CompanyOctober 7, 1988 - September 30,1990Total funding - $40,052 (plus 70% overhead returned to project)Principal Investigators: Z. Gurdal and O. Hayden Griffin, Jr.The responsibility of this project is equally divided between myself and Dr. GurdalMy share of the project funding was $20,026.

“Virginia Institute for Material Systems”Commonwealth of VirginiaJuly 1, 1988 - July 1, 1990Total funding 1988-89 - $353,208, 1989-1990 - $518,061, 1990-1991 - $487,871, 1991-1992 - $479,563 (excluding overhead)Principal Investigators: J. McGrath, K. L. Reifsnider, G. Wilkes, T. Ward, W. W. Stinchcomb, A. C. Loos, H. F. Brinson, O. H. Griffin, Jr., D. Baird.My share of the responsibility has been to serve as an Associate Director of VIMS and conduct research into the mechanical behavior of composite materials.My share of the project funding was: 1988-89 - $34,000, 1989-90 - $40,000, 1990-91 - $30,000, 1991-92 - $35,000, 1992-93, $18,843, 1993-94, $17,000 ($174,843 total).

“Automated Design of Composite Plates for Marine Applications”

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Virginia Center for Innovative Technology / Institute of Material Science and EngineeringNov 20, 1987 - Nov 19, 1988Total Funding - $34,543Principal Investigators: Z. Gurdal and O. Hayden Griffin, Jr.The responsibility of this project was equally divided between myself and Dr. GurdalMy share of the project funding was $17,271.

“Design of Composite Plates for Marine Vehicles”Newport News Shipbuilding & Dry Dock CompanyNov 20, 1987 - Nov 19, 1988Total funding - $37,997Principal Investigators: Z. Gurdal and O. Hayden Griffin, Jr.The responsibility of this project was equally divided between myself and Dr. GurdalMy share of the project funding was $18,998.

“Application of Composite Materials to Rail Transit Systems”NASA Langley Research Center and U.S. Department of TransportationMay 1, 1986 - April 30, 1987Total funding - $39,998Principal Investigators: C. T. Herakovich, O. H. Griffin, Jr., and Z. Gurdal.My portion of the project was to conduct a survey of the current uses and near-term planned uses of composite materials in urban mass transit systems. I also took the lead in writing the final report to the sponsors.My share of the funding was $18,000.

c. Invited research presentations outside ECU: Griffin, H., “Capturing Recent and Near Future Advances in Engineering Education,” Invited

presentation at The Ohio State University, January 2008. Griffin, H., “Innovation, Research, and Outreach in Engineering Education,” Invited presentation at

The Ohio State University, September 2007. Lohani, V. and Griffin, H., “A New Department of Engineering Education- Accomplishments in First

Year and Near-Term Goals,” Invited paper, International Conference on Engineering Education (iCEE 05), Gliwice, Poland, July 25-29, 2005.

Muffo, J., Lohani, V.K., Mullin, J., Backert, R., and Griffin, H., 2005, ‘From Engineering Fundamentals to Engineering Education –What’s in a Name?’, Invited Paper, International Conference on Engineering Education, February 28-March 5, 2005, Tainan, Taiwan.

Aning, A. O., Lohani, V.K., Griffin, H., Kampe, J.C.M., and Aref, H., ‘An Interdisciplinary Graduate Program in Engineering Education,’ Invited Paper, International Conference on Engineering Education, February 28-March 5, 2005, Tainan, Taiwan.

O. Hayden Griffin, Jr., “The Virginia Tech Department of Engineering Education: Present and Future,” presented at Purdue University, May 3, 2004.

O. H. Griffin, Jr., “Computational Structural Mechanics Needs Assessment,” presented at the Computational Structural Mechanics Branch Grant Review, October 23-24, 1991, NASA Langley Research Center, Hampton, Virginia.

O. H. Griffin, Jr., “Computational Mechanics Applied to Modern Materials and Structures,” invited lecture at the National Center for Supercomputing Applications, The Beckman Institute, University of Illinois, July 25, 1991.

O. H. Griffin, Jr. and D. M. Thompson, “2-D to 3-D Global/Local Finite Element Analysis of Laminated Composites,” invited presentation at the First U. S. National Congress on Computational Mechanics, Chicago, July 21-24, 1991.

O. H. Griffin, Jr., “The Use of Computers in the Evaluation of Three Dimensional Stress Effects in Composite Materials Products,” invited Keynote Address, presented at the Second International

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Conference on Computer Aided Design in Composite Material Technology, Brussels, Belgium, April 25-27, 1990, pp 171-187.

O. H. Griffin, Jr., “Development and Verification of Local/Global Analysis Techniques for Laminated Composites II,” invited presentation at the LaRC Grant Review/ACT Review, NASA Langley Research Center, Hampton, Virginia, May 16-19, 1989.

O. H. Griffin, Jr., “Development and Verification of Local/Global Analysis Techniques for Laminated Composites I,” invited presentation at the NASA Workshop on Computational Structural Mechanics, NASA Langley Research Center, Hampton, Virginia, 18-20 November, 1987, NASA Conference Proceeding 10012, N. P. Sykes, Editor, February 1989, pp 683-732.

d. Chapters of Books, Editor of Proceedings, Instructional Movies, Manuals Wrote article on “Composites” for Encyclopedia of Science and Technology, 1998. Wrote articles on “Simple Machines,” “Lever,” “Wheel and Axle,” “Pulley,” “Inclined Plane,” for

1998 and 1999 versions of Microsoft Encarta electronic encyclopedia. Computer Aided Design in Composite Material Technology III, S. G. Advani, W. R. Blain, W. P. de

Wilde, J. W. Gillespie, and O. H. Griffin, Jr., Editors, Computational Mechanics Publications and Elsevier Applied Science, Publishers, 1992.

e. Refereed Papers Presented at Major International or National Technical Meetings Prashanth Jayaraman, Vinod Lohani, Garrett Bradley, Hayden Griffin, and John Dooley 2008.

“Enhancement of an Engineering Curriculum Through International Experiences,” Proceedings of the 2008 ASEE Annual Conference and Exposition, Pittsburgh, PA, June 22-25, 2008.

Vinod Lohani, Ricky Castles, Jenny Lo, and Hayden Griffin, 2007. “Tablet PC Applications in a Large Engineering Program,” Proceedings of the 2007 ASEE Annual Conference and Exposition, Honolulu, HI, June 24-27, 2007.

Odis Hayden Griffin, Jr. and Susan Cortes, “A Learning Space Of, By, And For Engineers: Virginia Tech’s Joseph F. Ware, Jr. Advanced Engineering Laboratory,” Paper DETC2006-99205, Proceedings of IDETC/CIE 2006: 3rd Symposium on International Design and Design Education, September 10-13, 2006, Philadelphia, Pennsylvania

Jennifer Mullin, Hayden Griffin, Jenny Lo, Vinod Lohani, “Co-teaching a Freshman Engineering Course: A Collaboration Between Experienced Faculty and Novice Graduate Students,” 2006 ASEE Conference, Chicago, June 19-21, 2006

Sharnnia Artis, Glenda Scales, Hayden Griffin, “From the Classroom to the Boardroom: The Use of Role Play in Graduate Education,” 2006 ASEE Conference, Chicago, June 19-21, 2006

Jenny Lo, Vinod Lohani, Hayden Griffin, “Full Implementation of a New Format for Freshman Engineering Course at Virginia Tech,” 2006 ASEE Conference, Chicago, June 19-21, 2006

Jennifer Mullin, Hayden Griffin, Jenny Lo, Vinod Lohani, “Sustainable Development Design Projects for Engineering Freshmen,” 2006 ASEE Conference, Chicago, June 19-21, 2006.

Lohani, V. K., Lo, J., Mullin, J., Muffo, J., Backert, R., and Griffin, H., 2005. “Transformation of a Freshman Year Engineering Course,” International Conference on Engineering Education, July 25-29, 2005, Gilwice, Poland.

Lohani, V. K., Wildman, T., Connor, J., Mallikarjunan, K., Wolfe, M. L., Muffo, J., Knott, T.W., Lo, J., Loganathan, G.V., Goff, R., Gregg, M., Chang, M., Cundiff, J., Adel, G., Agblevor, F., Vaughan, D., Fox, E., Griffin, H., Mostaghimi, S., 2005. “Spiral Curriculum Approach to Reformulate Engineering Curriculum,” Work-in-progress paper, Frontiers in Education Conference, Indianapolis, IN, 18-21 October 2005.

Griffin, O. H. and T. Walker, “Faculty and Student Response to a Laptop Computer Requirement for Engineering Freshmen,” 2005 ASEE Annual Conference, Portland, Oregon.

Griffin, H., Aning, A., Lohani, V.K., Kampe, J., Goff, R., Paretti, M., Alley, M., Lo, J., Terpenny, J., Walker, T., Aref, H., Magliaro, S., and Sanders, M. 2005. “Designing and Implementing Graduate Programs in Engineering Education.” 2005 ASEE Annual Conference, Portland, Oregon.

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Lo, J., Goff, R., Lohani, V., Walker, T., Knott, T., and Griffin, H., 2005. “New Paradigm for Foundational Engineering Education.” 2005 ASEE Annual Conference, Portland, Oregon.

Knott, M., Lohani, V.K., Griffin, H., Loganathan, G.V., Adel, G., Paretti, M., Wolfe, M., Mallikajunan, K., and Wildman, T., 2005, “Using e-portfolios in a large engineering program.” 2005 ASEE Annual Conference, Portland, Oregon.

Snook, J., Lohani, V.K., Lo, J., Sirvole, K., Mullins, J., Kaeli, J., and Griffin, H., 2005. “Incorporation of a 3-D Interactive Graphics Programming Language into an Introductory Engineering Course.” 2005 ASEE Annual Conference, Portland, Oregon.

Lohani, V.K., Sanders, M., Wildman, T., Connor, J., Mallikarjunan, K., Dillaha, T., Muffo, J., Knott, T.W., Lo, J., Loganathan, G.V., Adel, G., Wolfe, M.L., Goff, R., Gregg, M., Chang, M., Agblevor, F., Vaughan, D., Cundiff, J., Fox, E., Griffin, H., and Magliaro, S., 2005, “From BEEVT to DLR NSF Supported Engineering Education Projects at Virginia Tech,” 2005 ASEE Annual Conference, June 12-15, Portland, Oregon.

O. Hayden Griffin, Jr., Edward A. Fox, Calvin J. Ribbens, Thomas D. L. Walker, Nathaniel J. Davis IV, Richard M. Goff, Jenny L. Lo, Vinod K. Lohani, Michael H. Gregg, and Dwight Barnette, “Work in Progress – A Freshman Course for Engineering and Computer Science Students,” presented at the IEEE/ASEE Frontiers in Education Conference, October 2004, Savannah, GA.

Snook, J.S., Lohani, V. K., Lo, J., Sirvole, K., Mullins, J., Kaeli, J., Griffin, H. 2005 “Use of a Graphical Programming Language in an Introductory Engineering Course.” Poster presented at ACM SIGCSE 2005, St. Louis, MO, February 23-27, 2005.

Lohani, V. K., Sanders, M., Knott, T., Griffin, H., Bull, E., McIntyre, S., Connor, J., Loganathan, G. V., Wildman, T., Adel, G., and Magliaro, S. 2004, “Engineering-Education Collaboration - Virginia Tech,” Proc. Int. Conference on Engineering Education, Gainesville, FL. Oct. 2004.

O. H. Griffin, Jr., “Hands On, 24/7 – Virginia Tech’s Joseph F. Ware Jr. Advanced Engineering Laboratory,” Proceedings of the 2004 ASEE Conference, Salt Lake City, UT.

J.B. Connor, V.K. Lohani, E. Bull, T.M. Wildman, S.G. Magliaro, T.W. Knott, O.H. Griffin, Jr, and J.A. Muffo, “An Analysis of Freshman Engineering: A Cross-College Perspective”, Proceedings of the 2004 ASEE Conference, Salt Lake City, UT.

T. W. Knott, V. K. Lohani, O.H. Griffin, Jr., G.V. Loganathan, G. T. , Adel, and T. M. Wildman, “Bridges for Engineering Education: Exploring ePortfolios in Engineering Education at Virginia Tech”, Proceedings of the 2004 ASEE Conference, Salt Lake City, UT.

E. Moas and O.H. Griffin, Jr., “Progressive Failure Analysis of Laminated Composite Structures,” 37th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials (SDM) Conference, April 1996, pp 2246-2256.

M. D. Sensmeier, P. K. Sensharma, R. T. Haftka, O. H. Griffin, Jr., and L. T. Watson, “Experimental Validation of Anti-optimization Approach for Detecting Delamination Damage,” Proceedings of the 36th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials (SDM) Conference, New Orleans, LA, April 1995, p 3717.

E.H. Glaessgen and O. H. Griffin, Jr., “Effect of Applied Boundary Condition on the Analysis of Composites Based on Woven Preforms,” Proceedings of the 36th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials (SDM) Conference, New Orleans, LA, April 1995, p 38.

D. Cohen, M. W. Hyer, O. H. Griffin, Jr., S. R. Yalamanchili, M. J. Shuart, and C. Prasad, “Strength Predictions for Thick Multi-Fastener Graphite-Epoxy Composite Joints,” ASTM Symposium on Bolted and Bonded Joints in Composite Materials, November 16-17, 1993, Fort Worth, Texas.

J. Lee, O. H. Griffin, Jr., and Z. Gurdal, “Postbuckling of Laminated Composites with Delaminations,” presented at the AIAA/ASME/ASCE/AHS/ASC 34th Structures, Structural Dynamics, and Materials Conference, La Jolla, California, April 1993.

E. E. Carapella, M. W. Hyer, and O. H. Griffin, Jr., “Micromechanics of Noncircular Fibers,” presented at the American Society for Composites 7th Technical Conference on Composite Materials, State College, PA, October 1992.

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N. L. Breivik, Z. Gurdal, and O. H. Griffin, Jr., “Compression of Laminated Composite Beams with Initial Damage,” presented at the American Society for Composites 7th Technical Conference on Composite Materials, State College, PA, October 1992.

D. Cohen, L. Q. Do, M. W. Hyer, O. H. Griffin, S. R. Yalamanchili, M. J. Shuart, and C. B. Prasad, “Failure Criterion for Thick Multi-Fastener Graphite/Epoxy Composite Joints,” Proceedings of the 6th Japan-U.S. Conference on Composite Materials, Orlando, Florida, 22-24 June, 1992.

Danniella Muheim Thompson, David H. Mollenhauer, O. Hayden Griffin, Jr., “Finite Element Analysis of Smart Structures,” in Computer Aided Design in Composite Material Technology III, S. G. Advani, W. R. Blain, W. P. de Wilde, J. W. Gillespie, and O. H. Griffin, Jr., Editors, Computational Mechanics Publications and Elsevier Applied Science, Publishers, 1992, pp 419-429.

D. M. Thompson and O. H. Griffin, Jr., “Finite Element Predictions of Active Buckling Control of Stiffened Panels,” Proceedings of the Conference on Recent Advances in Adaptive and Sensory Materials, Blacksburg, Virginia, April 27-29, 1992, pp 377-384.

O. H. Griffin, Jr., M. W. Hyer, S. R. Yalamanchili, M. J. Shuart, C. B. Prasad and D. Cohen, “Analysis of MultiFastener Composite Joints,” Proceedings of the AIAA/ASME/ASCE/AHS/ASC 33rd Structures, Structural Dynamics, and Materials Conference, Dallas, April 13-15, 1992, pp 745-753.

J. Lee, Z. Gurdal, and O. H. Griffin, Jr., “A Layer-wise Approach for the Bifurcation Problem in Laminated Composites with Delaminations,” Proceedings of the AIAA/ASME/ASCE/AHS/ASC 33rd Structures, Structural Dynamics, and Materials Conference, Dallas, April 13-15, 1992, pp 10-20.

E. Moas, R. L. Boitnott, and O. H. Griffin, “An Experimental and Analytical Investigation of the Failure of Gr/Ep Composite I-Frames,” Proceedings of the 1991 American Helicopter Society (AHS) National Technical Specialists’ Meeting on Rotorcraft Structures Technology for the 1990’s and Beyond, Williamsburg, VA, October 28-31, 1991.

D. M. Thompson and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Symmetric Composite Laminates with Holes,” Proceedings of the Thirteenth Canadian Congress of Applied Mechanics, University of Manitoba, Winnipeg, Manitoba, June 2 - June 6, 1991, pp 200-201.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “Minimum Weight Design of Composite Plates for Postbuckling Performance,” Proceedings of the AIAA/ASME/ASCE/AHS/ASC 32nd Structures, Structural Dynamics, and Materials Conference, April 8-10, 1991, Baltimore, Maryland, pp 257-267.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “Minimum Weight Design of Laminated Composite Plates for Postbuckling Performance,” Proceedings of the Second Pan American Congress of Applied Mechanics, Vina del Mar, Chile, January 1991, pp 580-583.

O. H. Griffin, Jr., “The Use of Computers in the Evaluation of Three Dimensional Stress Effects in Composite Materials Products,” invited Keynote Address, in Composite Materials Design and Analysis, Proceedings of the Second International Conference on Computer Aided Design in Composite Material Technology, Brussels, Belgium, April 25-27, 1990, Springer Verlag, New York, pp 171-187.

D. M. Thompson and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Composite Laminates,” Proceedings of the 4th Technical Conference of the American Society for Composites, Blacksburg, Virginia, October 3-6, 1989.

S. S. Lane, R. H. Moore, G. V. Gandhe, and O. H. Griffin, Jr., “Eddy Current Inspection of Graphite/Epoxy Laminates,” Proceedings of the 4th Technical Conference of the American Society for Composites, Blacksburg, Virginia, October 3-6, 1989.

D. E. Bowles and O. H. Griffin, Jr., “Analysis of Thermal Stresses in Polymer Matrix Composites,” Proceedings of the 34th International SAMPE Symposium, Reno, Nevada, May 8-11, 1989.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “A Penalty Approach for Nonlinear Optimization with Discrete Design Variables,” Proceedings of the Association for Applied Mathematics and Mechanics (GAMM) Seminar on Discretization Methods and Structural Optimization - Procedures and Applications, University of Siegen, Federal Republic of Germany, October 3-5, 1988.

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D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “A Penalty Approach for Nonlinear Optimization with Discrete Design Variables,” Proceedings of the Second NASA/Air Force Symposium on Recent Advances in Multidisciplinary Analysis and Optimization, September 28-30, 1988, Hampton, Virginia.

O. H. Griffin, Jr. and M. A. Vidussoni, “Local/Global Finite Element Analysis of Composite Materials,” in Computer Aided Design in Composite Material Technology, Proceedings of the International Symposium, Southampton, UK, April 13-15, 1988, C. A. Brebbia, W. P. de Wilde, and W. R. Blain, Editors, Springer-Verlag, 1988, pp 513-524.

M. D. Sensmeier, O. H. Griffin, Jr., and E. R. Johnson, “Effect of Axial Impact on the Static Flexure of Graphite/Epoxy Beams,” Proceedings of the Joint ASC/CCM Symposium on Composites Science and Engineering, University of Delaware, Newark, DE, September 1987.

C. R. Wilson and O. H. Griffin, Jr., “An Integrated Multi-computer Network for a Research Center,” Proceedings of the 1983 ASME International Computers in Engineering Conference, Chicago, August, 1983.

J. C. Roberts and O. H. Griffin, Jr., “Analytical/Experimental Heat Transfer in Dry Sliding of Polymeric Composites,” Proceedings of the ASME-ASLE Joint Lubrication Conference, Washington, DC, October 5-7, 1982.

O. H. Griffin and C. M. Blackmon, “Finite Element Stress Analysis of U.S. Navy MARK 83 Base Detonating Fuze Body,” Proceedings of the Army Symposium on Solid Mechanics, Cape Cod, September, 1978.

C. R. Crowe, W. Holt, W. Mock, and O. H. Griffin, “Dynamic Fracture and Fragmentation of Cylinders,” Proceedings of the International Congress on Materials II, Boston, August 16-20, 1976.

f. Formal Reports Printed and Circulated by Agencies of the State or Federal Governments O. H. Griffin, Jr., and E.H. Glaessgen, “Finite Element Based Micro-Mechanics Modeling of Textile

Composites,” in NASA Conference Publication 3311 (Part 2), C. C. Poe, Jr. and C. E. Harris, Editors, NASA, October 1995, pp 555-586.

Lucie Parietti and O. H. Griffin, Jr., “Micromechanical Finite Element Model for Constitutive Elastoplastic Analysis of Unidirectional Fiber-Reinforced Composites,” VPI&SU Center for Composite Materials and Structures report CCMS-94-11), August 1994.

E. E. Carapella, M. W. Hyer, and O. H. Griffin, Jr., “Micromechanics of Crenulated Fibers in Carbon/Carbon Composites,” VPI&SU College of Engineering Report VPI-E-93-01 (CCMS-93-01), January 1993.

S. R. Yalamanchili, M. W. Hyer, O. H. Griffin, Jr., M. J. Shuart, C. B. Prasad and D. Cohen, “Analysis of MultiFastener Composite Joints: Numerical and Experimental Results,” VPI&SU College of Engineering Report VPI-E-92-14 (CCMS-92-15), June 1992.

J. Lee, O. H. Griffin, Jr., and Z. Gurdal, “Vibration, Buckling and Postbuckling of Laminated Composites with Delaminations,” VPI&SU College of Engineering Report VPI-E-92-13 (CCMS-92-13), June 1992.

N. L. Breivik, Z. Gurdal, and O. H. Griffin, Jr., “Compression of Thick Laminated Composite Beams with Initial Impact-Like Damage,” VPI&SU College of Engineering Report VPI-E-92-15 (CCMS-92-16) June 1992.

D. H. Mollenhauer and O. H. Griffin, Jr., “Induced Strain of Actuation of Surface Bonded and Embedded Piezoceramic Patches”, VPI-E-92-09 (CCMS-92-08) April, 1992

S. Y. Hsu and O. H. Griffin, Jr., “Efficient Endochronic Finite Element Analysis: An Example of a Cyclically Loaded Boron/Aluminum Tube,” VPI&SU College of Engineering Report VPI-E-92-8, April 1992.

S. K. Jain, S. Y. Hsu, and O. Hayden Griffin, Jr., “On the Models of Hereditary Evolutions of Plasticity,” VPI&SU Report VPI-E-91-13, June, 1991.

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D. M. Thompson and O. H. Griffin, Jr., “Development and Verification of Global/Local Analysis Techniques for Laminated Composites,” NASA Contractor Report CR-185060, (VPI-E-91-12), June 1991.

D. M. Thompson and O. H. Griffin, Jr., “Two-Dimensional to Three-Dimensional Global/Local Finite Element Analysis of Laminated Composites in Compression,” VPI&SU CCMS Report CCMS-91-14 (VPI-E-91-11), June 1991.

S. Y. Hsu and O. H. Griffin, Jr., “On Stability and Efficiency of Numerical Integration of Endochronic Constitutive Equations,” College of Engineering Report VPI-E-91-06, May 1991.

N. F. Knight, Jr., J. B. Ransom, O. H. Griffin, Jr., and D. Muheim Thompson, “Global/Local Methods Research Using the CSM Testbed,” Proceedings of the Eighth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, compiled by J. H. Starnes, Jr., H. L. Bohon, and S. B. Garzon, NASA Conference Proceeding, CP-3087, Part 1, 1990, pp 281-309.

M. A. Vidussoni and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Cross-ply Composite Laminates,” VPI&SU Report CCMS-90-09, September, 1990.

G. V. Gandhe and O. H. Griffin, Jr., “Impact Response of Interleaved Composites,” VPI&SU Report CCMS-90-01, March, 1990.

S. Y. Hsu, S. K. Jain, and O. Hayden Griffin, Jr., “Numerical Integration of the Constitutive Equations of the Endochronic Theory of Plasticity,” VPI&SU Report VPI-E-90-02, January, 1990.

S. Y. Hsu, S. K. Jain, and O. Hayden Griffin, Jr., “A Procedure for Determining Endochronic Material Functions and Verification of Endochronic Theory for Nonproportional Loading Paths,” VPI&SU Report VPI-E-89-25, June, 1989.

S. Y. Lin, O. H. Griffin, Jr., and R. M. Barker, “Feasibility of Fiber Reinforced Composite Materials Used in Highway Bridge Superstructures,” VPI&SU Report CCMS-89-05, December, 1988.

CCMS Five Year Plan Committee (O. H. Griffin, Jr., Chairman, C. E. Bakis, D. Frederick, Z. Gurdal, J. Morton, D. Post, W. W. Stinchcomb, and R. E. Swanson), “History, Current Status, and a Five-Year Plan for the VPI&SU Center for Composite Materials and Structures,” CCMS Report, April 1988.

O. H. Griffin, Jr., Z. Gurdal, and C. T. Herakovich, “Composite Materials for Rail Transit Systems,” NASA Contractor Report 178401, December, 1987.

J. L. Sevart, O. Hayden Griffin, Jr., and Z. Gurdal, “Flammability and Toxicity of Composite Materials,” VPI&SU Report VPI-E-87-33, December, 1987.

M. D. Sensmeier, O. H. Griffin, Jr., and E. R. Johnson, “Static and Dynamic Large Deflection Flexural Response of Graphite-Epoxy Beams,” VPI&SU Report CCMS-87-07 (VPI-E-87-7), May 1987. Also published as NASA Contractor Report 4118, March 1988.

O. H. Griffin, Jr., M. P. Kamat, and C. T. Herakovich, “Three Dimensional Inelastic Finite Element Analysis of Laminated Composites,” VPI&SU Report VPI-E-80-28, November, 1980. Also published as NASA Contractor Report CR-163712.

Approximately ten U.S. Naval Surface Weapons Center (now Naval Surface Warfare Center) reports, most unclassified, some classified.

I authored portions of “Virginia Institute for Materials Systems (VIMS) Interim Report” and “VIMS Final Report,” 1989 and 1990.

g.Patents/disclosures/copyrights:US Patent No. 5,612,505 “Dual Mode Warhead,” J.S. O’Brasky, A. A. Alexander, O. H. Griffin, Jr., J. S. Foster, M. C. Shamblen, March 18, 1997

5.Other: November 1983 - September 1985, Assistant Supervisor, Engineering Design Group, Johns Hopkins

University/Applied Physics Laboratory, Laurel, Maryland

Responsible for technical activities, primarily in mechanical design area, of Engineering Design Group. This group was in the same Branch as the electrical and mechanical fabrication shops, and definition and

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improvement of communication between these groups was a part of the job. Interfaced with other groups at the Laboratory to obtain projects for Engineering Design Group, which was at that time composed of 50 to 60 personnel including engineers, manual designer/drafters, CAD operators, and CAM programmers. Made both formal and informal presentations on Group capabilities and activities to both technical and management audiences. Prepared time and cost estimates for engineering jobs, supervised work, reviewed reports, and prepared performance appraisals of engineers in the Group. Supervised and participated in design of an all composite center support column for a satellite being designed and fabricated at APL. Played primary role in introducing workstation-based computer aided mechanical engineering tools to APL. Heavily involved in both hardware and software selection during a project to convert all designer/drafters at APL to CAD/CAM/CAE technology.

February 1981 - October 1983, Member, Technical Staff, Bendix Advanced Technology Center, Columbia, Maryland

Responsible for proposing, planning, and executing the composite mechanics portion of a multi-disciplinary applied research project aimed at bringing advanced composites technology into the Bendix Corporation. Areas of research included analysis of environmental and processing-induced stresses in composites, the objective being to determine means of producing laminates with extreme long-term dimensional stability. Also studied the use of micromechanics analysis to predict the thermomechanical properties of hypothetical composites. Unpublished work includes analyses conducted to determine induced stress fields and thus validate a number of non-standard tests used by Bendix personnel to evaluate experimental composite materials. Consulted with Bendix divisional personnel in the area of composite mechanics and design, including both new introduction of these materials and analysis and understanding of in-service behavior. Applications consulted on included composite airplane driveshaft, composite probe arm for precision measurement device, and composite/steel actuators for aircraft. Developed software and conducted studies of feasibility of using microprocessor based personal engineering workstations for performance of small to large scale finite element analysis.

November 1979 - February 1981, Senior Tire Development Engineer, BF Goodrich, Tire Analysis Research, Akron, Ohio

Proposing and conducting numerical research to determine proper techniques for finite element analysis of tires using both the material and geometric nonlinearity capabilities of ADINA. Research in proper application of finite element analysis to orthotropic materials. Investigated using the finite element heat transfer program ADINAT for modeling of the tire curing process. Developed pre-/post-processing and stiffness bandwidth minimization software for ADINA and ADINAT. Utilized a variety of computer tools, including DEC and IBM computers and Versatec, Tektronix, and Ramtek graphics devices.

May 1971 - October 1979, Mechanical Engineer and Aerospace Engineer, U.S. Naval Surface Weapons Center, Dahlgren, Virginia

Structures and materials specialist. Involved in design, analysis, and testing of ordnance hardware. Extensive use of finite element analysis of elastic and elastic-plastic response. Participated in research on heat transfer and loading of large caliber gun barrels and ammunition during firing and several in-service malfunction investigations. Involved in the design, prototype development, and prototype testing of the dual mode warhead for the SMAW weapon. This development was granted a Certificate of Patentability by the U.S. Navy (not patented until 1997 because of security classification). Had responsibility for building, maintaining, and user training for a library of numerical analysis (finite difference and finite element) software. Conducted numerical analysis of jointed projectile response to oblique target impact and inelastic response of composite laminates.

Awards at Virginia Tech- Academy of Teaching Excellence, 2008 Inductee- Alumni Teaching Award – 2008 (two awards per year are made across the University)

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- Diggs Teaching Scholar – 2006 (no more than 3 awards per year are made across the University)- Certificate of Teaching Excellence – Virginia Tech College of Engineering for academic years 1997-

98 and 2004-05 (no more than 4 awards per year made in the College)

Professional RegistrationRegistered Professional Engineer (Certificate 008474) in Virginia since 1976. License is current.

ConsultingHave worked with a number of attorneys in analysis of failure of consumer products and vehicle accident-related investigations.

Professional Societies- Member of American Society for Engineering Education (ASEE)- National Academic Advising Association (NACADA)

EducationFrom 2004-2010 took graduate courses in the Virginia Tech School of Education in the area of Curriculum and Instruction. Courses taken include Advanced Educational Psychology, Principles of Instructional Design, Foundations of Educational Research, Program and Platform Evaluation, Research Assessing Student Achievement and Cognitive Processes & Education.

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Faculty Information SheetName: Barbara Jean Muller-Borer, Ph.D.

1.Rank: Associate Professor - Department of Cardiovascular Sciences, The Brody School of Medicine at East Carolina University 2011-presentAdjunct Professor - Departments of Biology East Carolina University 2007 - presentAdjunct Professor - Department of Engineering, East Carolina University 2010-present

2.Degrees:BS 1979, Tufts University School of Engineering, Medford, MA.

Engineering Psychology, Deflorez Prize in Human Engineering Senior Undergraduate Award, Tau Beta Pi Engineering Honor Society, Magna Cum Laude.

MS 1986, The University of North Carolina at Chapel Hill, Chapel Hill, NC. Biomedical Engineering Thesis: “Control Electronics for an Implantable Hydrocephalic Shunt”.

Ph.D. 1991, The University of North Carolina at Chapel Hill, Chapel Hill, NC. Biomedical Engineering Dissertation: “The Effects of Cellular Uncoupling on Action Potential Propagation in Ventricular Tissue: A Computer Modeling and Simulation Study”.

Postdoctoral Fellowship 1991-1994, The University of North Carolina School of Medicine, Division of Cardiology, Chapel Hill, NC. Cardiovascular Modeling.

NIH Postdoctoral Fellowship 1994–1996, The University of North Carolina School of Medicine, Division of Cardiology Chapel Hill, NC. Cardiovascular Physiology.

Postdoctoral Fellowship 1996-1998, The University of North Carolina School of Medicine, Division of Cardiology Chapel Hill, Cardiovascular Imaging.

3. Teaching Experience related to proposed degree (with emphasis on the past five years):Workload Assignment: 10% teaching, 80% research, 10% serviceLecturer2005 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells and Tissue

Bioengineering”, Fall Semester, 2 lectures and 1 laboratory.2005 Division of Cardiology, Electrophysiology Noon Conference, ”Cardiac Regenerative Cell

Therapy”.2006 Department of Biology, BIOL 6880 Seminar, “Cardiovascular Translational Biology

Laboratories”. Fall Semester.2006 Division of Cardiology Grand Rounds, CME, “Cell-Based Therapy for Cardiovascular Disease”.2006 Department of Biochemistry, Graduate Seminar, “Plasticity of a Liver Adult Stem Cell in a Cardiac

Myocyte Microenvironment”.2007 Department of Biology, BIOL 6880 Seminar, “Cardiovascular Translational Biology

Laboratories”. Fall Semester.2007 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells and Tissue

Bioengineering”, Fall Semester, 2 lectures and 1 laboratory.2007 Division of Cardiology Grand Rounds, CME, “Cell-Based Therapy for Cardiovascular Disease”.2008 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells and Tissue

Bioengineering”, Fall Semester, 2 lectures.2008 Department of Pathology, Grand Rounds, CME, “Stem Cell Differentiation into Cardiac

Myocytes”.2008 Department of Anatomy and Cell Biology, Graduate Seminar, “Stem Cell Differentiation in a

Cardiac Microenvironment”.2009 Department of Engineering, BIME 3000, “Introduction to Biomedical Engineering”, Fall Semester.

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2009 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Laser Capture Microdissection”, Fall Semester, 1 lecture and laboratory.

2009 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Laser Capture Microdissection”, Fall Semester, 1 lecture and laboratory.

2009 Department of Cardiovascular Sciences, Grand Rounds, CME, “Cardiac Regeneration and Cell-Based therapies for Ischemic Heart Disease”.

2010 Department of Engineering, BIME 4040, “Physiological Systems and Modeling for Engineering”, Spring Semester, 2 lectures per week, 15 weeks.

2010 Department of Cardiovascular Sciences, “Overview of Regenerative Medicine Research and Laser Capture Microdissection”. Lecture to NCState Park Fellows.

2010 Department of Physiology, “Gap Junctions: Intercellular Channels”, Lecture to graduate and undergraduate students in Tulis Laboratory.

2010 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells and Tissue Bioengineering”, Fall Semester, 2 lectures and 1 laboratory.

2010 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Laser Capture Microdissection”, Fall Semester, 1 lecture and laboratory.

2010 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Cell Culture Techniques”, Fall Semester, 1 lecture and laboratory.

2010 Department of Engineering, BIME 3000, “Introduction to Biomedical Engineering”, Fall Semester.2010 Department of Biology, BIOL 6880 Seminar, “Cardiovascular Translational Biology

Laboratories”. Fall Semester.2010 Instructor, Brody School of Medicine Personal Professional Leadership Program.

Seminars2004 Department of Physiology, Journal Club, “Stem Cell Trans-Differentiation in a Cardiac Myocyte

Microenvironment”, October 2004.2005 Metabolic Studies Research Group, “Stem Cell Plasticity in the Cardiovascular System”, February

2005.2005 Department of Surgery, “Cardiovascular Translational Biology Laboratories”, Presentation to

visiting professor Frank Selke, MD and surgical residents, October 2005.2006 Division of Endocrinology and Metabolic Studies Group, “Confocal Fluorescence Microscopy”,

January 2006.2007 Stem Cell Interest Group, “Stem Cell Trans-Differentiation in a Cardiac Myocyte

Microenvironment”, February 2007.2007 East Carolina University Brody School of Medicine Confocal Microscopy Symposium, “Gap

Junction Coupling and Calcium Signaling in Live Cell Cultures”, November 2007.2008 Stem Cell Interest Group, “Review of Symposium on Cardiovascular Regenerative Medicine –

October 2007”, February 2008.2008 Metabolic Studies Research Group, “Mechanisms Controlling the Acquisition of a Cardiac

Phenotype by Liver Stem Cells”, March 2008.2009 Stem Cell Interest Group, “Induced Pluripotent Stem Cells”, December 2009.

Course Director2007 Liaison to UNC-Chapel Hill, Fall 2007. Webcast, “Stem Cells and Maturational Lineage Biology:

Relevance in Quiescent, Regenerative and Diseased Tissues and in Clinical/Commercial Programs in Tissue Engineering and Cell Therapies Course # 625”. Collaborated with Lola Reid, PhD, UNC-Chapel Hill to coordinate the webcast of 3 weekly lectures for 16 weeks. This was the first time the course was taught over the internet using the NCREN system.

2010 East Carolina University Department of Engineering, BIME 4040, “Physiological Systems and Modeling for Engineering”, Spring Semester 2010. Developed and taught course, 2 lectures per

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week for 15 weeks. This was the first time the course was offered in the biomedical engineering concentration.

2010 Core Faculty and Research Advisor for Interventional Cardiology Program, Department of Cardiovascular Sciences.

Graduate student supervisory experience (theses/dissertations):Doctoral Student Committee

2008 – 2011 Member of doctoral student committee, Jessica Dries, PhD Candidate, Department of Physiology, “EphrinA1/EphA Receptor Tyrosine Kinase Signaling in Myocardial Infarct Repair”.

Doctoral Student Training2006 Preceptor, Jessica Dries, First year graduate student, Department of Physiology.

Doctoral student laboratory rotation.2008 Preceptor, Di Wu, First year graduate student, Department of Physiology.

Doctoral student laboratory rotation.

Surgical and Internal Medicine Residents2005 - 2006 Co-advisor, George Hart Tyson, MD. Third year Surgical Resident research

project, “Evaluating Microbead Injection Techniques in a Porcine Heart”. 2006 Preceptor, Christopher Karkut, MD, First year Internal Medicine Resident.

Laboratory rotation. 2006 - 2007 Co-advisor, Wes Hudson, MD. Third year Surgical Resident research project,

“Evaluating Stem Cell Delivery Techniques and Analysis in a Porcine Model”. 2006 - 2007 Co-advisor, Dorian deFreitas, MD. Third year Surgical Resident research project,

“Developing a Rodent Bypass Model”. 2008 Preceptor, Jacqueline Carter, MD. Third year Surgical Resident. Laboratory

methods and training.

Masters Students 2006 – 2008 Co-Advisor, Master’s student thesis project, Graham V. Byrum III. Research

project/thesis. “Role of Thymosin Beta-4 in hMSC engraftment and differentiation in myocardial tissue “. Wake Forest Medical School, Class of 2012

2006 - 2008 Advisor, Master’s student thesis project, Yasmeen Midgette, Department of Biology. Research project/thesis, “The Effect of Mechanical Stress on the Differentiation of Mesenchymal Stem Cells into a Cardiac Phenotype in Vitro “.

2007 - 2008 Advisor, Master’s student, Catherine Gouge, Department of Biology.2008 – 2009 Advisor, Master’s student thesis project, Maria C. Collins, Department of

Biology. Research project/thesis “Expression of cardiogenic markers in bone marrow derived hMSC’s using mechanical strain and treatment with growth factors”.

2010 – 2011 Advisor, Master’s student thesis project, Katherine Crifasi, Department of Biology. Research project/thesis “What Degree of Protection does T4 hold for MSCs against Hypoxia Induced Apoptosis?”

Medical Students 2006 Mentor, Christopher Karkut (M4), East Carolina University Brody School of

Medicine. Individually designed selective in Cell-Based Therapy and Tissue Engineering Laboratory, “Evaluating Effects of LPS on Gap Junction Expression in Adult Stem Cells”.

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2007 Research co-advisor, Brian Burrows, “Cellular loss associated with xenographic mesenchymal stem cell cardiomyopathy”. Brody School of Medicine Summer Scholars Research Program.

2009 Research advisor, Joseph B. Padgett, ”Thymosin Beta 4's Wound Healing Propensity and the Heart “. Brody School of Medicine Summer Scholars Research Program.

2010 Research co-advisor, Richard Elliott Overman, Jr,. “Effects of BAY 41-2272 on Connexin 43 Expression in Vascular Smooth Muscle Cells.” Brody School of Medicine Summer Scholars Research Program.

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)a. Publications/Scholarly Activity related to proposed degree:

Muller-Borer BJ, Erdman D, Buchanan JW. "Electrical Coupling and Impulse Propagation in Anatomically Modeled Ventricular Tissue". IEEE Transactions in Biomedical Engineering (IF 1.857) 1994:41(5);445-454.

Muller-Borer BJ, Johnson TA, Gettes LS, Cascio WE. "Directional Differences in Propagation in a Modeled Ischemic Border Zone". Journal of Cardiovascular Electrophysiology (IF 3.703) 1995:6(12);1101-1112.

Hyatt CJ, Lemasters JJ, Muller-Borer BJ, Johnson TA, Cascio WE. "A Superfusion System to Study Border Zones in Confluent Cultures of Neonatal Rat Heart Cells". American Journal of Physiology (IF 4.0) 1998:274;H2001-H2008.

Muller-Borer BJ, Yang H, Marzouk SA, Lemasters JJ, Cascio WE. "Measurement of Endocardial and Subendocardial pHi and pHo in Perfused Rabbit Papillary Muscles by Confocal Fluorescent Microscopy". American Journal of Physiology (IF 4.0) 1998:275(6 pt 2);H1937-H1947.

Henriquez AP, Vogel R, Muller-Borer BJ, Henriquez CS, Weingart R, Cascio WE. "Influence of Dynamic Gap Junction Resistance on Impulse Propagation in Ventricular Myocardium: A Computer Simulation Study". Biophysical Journal (IF 4.507) 2001 Oct;81(4):2112-21.

Cascio WE, Yang H, Johnson TA, Muller-Borer BJ, Lemasters JJ. "Electrical Properties and Conduction in Reperfused Papillary Muscle". Circulation Research (IF 9.7) 2001 Oct 26;89(9):807-14.

Muller-Borer BJ, Cascio WE, Anderson PAW, Snowwaert JN, Frye JR, Desai N, Bagnell CR, Coleman WB, Grisham JW, Malouf NN. "Adult Derived Liver Stem Cells Acquire a Cardiac Myocyte Structural and Functional Phenotype in Culture". American Journal of Pathology (IF 6.039) 2004 July;165(1): 135-45.

Cascio WE, Yang H, Muller-Borer BJ, Johnson TA "Ischemia-Induced Arrhythmia: The Role Of Connexins, Gap Junctions, And Attendant Changes In Impulse Propagation”. Journal of Electrocardiology (IF 1.2) 2005 Oct;38(4 Suppl):55-9.

Muller-Borer BJ, Cascio WE, Grisham JW, Anderson PAW, Malouf NN “Acquired Cell-to-Cell Coupling and Cardiac-Like Calcium Oscillations in Adult Stem Cells in a Cardiomyocyte Microenvironment”. Proceedings of the 28th IEEE Engineering in Medicine and Biology Society, 2006;1:576-579.

Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN. “Mechanisms Controlling The Acquisition Of A Cardiac Phenotype By Liver Stem Cells”. Proceedings of the National Academy of Sciences (IF 10.231) 2007 March; 104(10): 3877-3882.

Hudson W, Collins MC, Dorian deFreitas D, Sun, YS, Muller-Borer BJ, Kypson AP. “Beating And Arrested Intramyocardial Injections Are Associated With Significant Mechanical Loss: Implications For Cardiac Cell Transplantation”, Journal of Surgical Research (IF 2.087) 2007 Oct;142(2):263-7.

Anderson PAW, Muller-Borer BJ, Esch GK, Coleman WB, Grisham JW, Malouf NN. “Calcium Signals Induce Liver Stem Cells to Acquire a Cardiac Phenotype”. Cell Cycle (IF 4.087). 2007 Jul;6(13):1565-9.

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Muller-Borer BJ, Collins MC, Gunst PR, Cascio WE, Kypson AP. “Quantum Dot Labeling of Mesenchymal Stem Cells”. Journal of Nanobiotechnology (IF 5.09) 2007 Nov. 7, 5-9.

b. Book Chapters Gettes LS, Cascio WE, Johnson TA, Muller-Borer BJ, and the Experimental Cardiology Group.

Characteristics and causes of conduction changes associated with 1a and 1b arrhythmias in acute ischemia. In: Discontinuous Conduction in the Heart. Spooner PM, Joyner RW, Jalife J, editors. American Heart Association Monograph Series. Futura Publishing Company, Inc., Armonk, New York, 1997, pp 441-452.

Lemasters JJ, Qian T, Trollinger DR, Muller-Borer BJ, Elmore SP, Cascio WE. Laser Scanning Confocal Microscopy Applied to Living Cells and Tissue. In: Methods in Cellular Imaging. Periasamy A, editor. Published for the American Physiological Society by Oxford University Press, New York, NY, 2001, Chapter 5 (pp 66-87).

c. Abstracts Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Lemasters JJ, Anderson PAW, Grisham JW,

Malouf NN. “Cardiac-Like Calcium Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”, Proceedings of the Gordon Research Conference in Cardiac Arrhythmia Mechanisms, February 2005.

Graff DW, Cascio WE, Muller-Borer BJ, Aghajanian A,. Sama P, Yan GX,. Devlin RB. "Zinc Produces a Transmural Voltage Gradient and Disruption of Intercellular Communication in the Heart”. Society of Toxicology, March 2005.

BJ Muller-Borer, WE Cascio, GL Esch, DW Graff , JJ Lemasters, PAW Anderson, JW Grisham, NN Malouf. “Cardiac-Like Calcium Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”. Proceedings of the 2005 BSOM Department of Internal Medicine Research Day, May 2005.

Lindsey CW, Muller-Borer BJ, Yang H, Cascio WE. "BAYK8644 Enhances Longitudinal Conduction Velocity in Depolarized Ischemic Myocardium: Possible Role for ICa in Impulse Propagation". Proceedings of the 2005 BSOM Department of Internal Medicine Research Day, May 2005.

Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Aghajanian A, Kim HS, Lemasters JJ, Kim JS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN, “Calcium Driven Transcription of a Cardiac Specifying Gene Program in Liver Stem Cells”. Circulation, 2005:112(17); II-266.

Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Kim HS, Lemasters JJ, Kim JS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN, “Cardiac-Like Oscillations in Liver Stem Cells Induce Their Acquisition of a Cardiac Phenotype”. Proceedings of the American Society of Cell Biology, Dec. 2005.

Tyson GH, Muller-Borer BJ, Cascio WE, Chitwood WR, Kypson AP, “Cell Therapy Infusion Device”. Proceedings of the 9th Annual NewEra Cardiac Care Meeting, January 2006.

Burrows BJ, Gunst PR, Muller-Borer BJ, Cascio WE, Johnson TA, “Identification Of Border Zones In Swine Cardiac Tissue With The Use Of A Typhoon Variable Mode Imaging System”. Proceedings of the 2006 BSOM Department of Internal Medicine Research Day, May 2006.

Gunst PR, Collins M, Burrows BJ, Kypson AP, Muller-Borer BJ, “Viability Of Mesenchymal Stem Cells Labeled With Quantum Dot Nano Particles”. Proceedings of the 2006 BSOM Department of Internal Medicine Research Day, May 2006.

Muller-Borer BJ, Gunst PR, Collins MC Cascio WE, Kypson AP, “Long-Term Labeling of Mesenchymal Stem Cells Using Quantum Dot Bioconjugates”. Circulation, 2006:114(18); II-662.

Kypson A, Tyson H, Collins M, Sun Y, Nifong W, Muller-Borer B. “Significant Mechanical Loss Is Associated With Direct Intramyocardial Injection For Cellular Cardiomyoplasty”. Journal of Surgical Research, 2007:137(2);.295.

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Collins MC, Hudson W, deFreitas D, Sun YS, Muller-Borer BJ, Kypson AP. “Beating And Arrested Intramyocardial Injections Are Associated With Significant Mechanical Loss: Implications For Cardiac Cell Transplantation”, Proceedings of the 2007 BSOM Department of Internal Medicine Research Day, May 2007.

Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN, Mechanisms Controlling the Acquisition of a Cardiac Phenotype by Liver Stem Cells”. Proceedings of the 2007 BSOM Department of Internal Medicine Research Day, May 2007.

Burrows BJ, Collins MC, Muller-Borer BJ, Kypson AP.”Cellular Cardiomyoplasty: Results of Injected Human Mesenchymal Stem Cell Survival Rates in a Beating Rat Heart Model”. Journal of Surgical Research, 2008: 144(2);274-5

Carter JJ, Manwaring ML, Salleng KJ, Muller-Borer BJ, Collins MC, Stoner MC.” Paralysis and Cell Death from Thoracic Aortic Stenting Ameliorated by Peroxynitrite Decomposition Catalyst”. Journal of the American College of Surgeons 2008; 207(3 sup.):22.

Collins MC, Gunst PR, Virag JI, Muller-Borer BJ. “Thymosin-4 Treatment of Human Mesenchymal Stem Cells and Cardiomyocytes”. Proceedings of the 2008 BSOM Department of Internal Medicine Research Day, May 2008.

Byrum GV, Collins MC, Muller-Borer BJ, Virag JI. “ Role of Thymosin-4 in Human Mesenchymal Stem Cell Engraftment, survival and Differentiation in Murine Myocardium”. Proceedings of the 2008 BSOM Department of Internal Medicine Research Day, May 2008.

Midgette YA, Collins MC, Gunst PR, Muller-Borer BJ, “The Effects of Mechanical Strain on the Differentiation of Mesenchymal Stem Cells into a Cardiac Phenotype In Vitro”. Proceedings of the 2008 BSOM Department of Internal Medicine Research Day, May 2008.

Collins MC, Muller-Borer BJ, “Expression of Cardiogenic Markers in Bone Marrow Derived hMSC’s using Mechanical Strain and Treatment with Growth Factors”. Proceedings of the 2009 BSOM Department of Internal Medicine Research Day, April 2009.

Collins MC, Gunst PR, Byrum G, Virag JI, Muller-Borer BJ, “Thymosin β4 Pretreatment of Human Mesenchymal Stem Cells and Rat Neonatal Cardiomyocytes”, Proceedings of the Keystone Symposia on Molecular and Cellular Biology. Cardiac Disease: Development, Regeneration and Repair (D1), June 2009.

Moore JL ,Collins MC, Virag, JI, Muller-Borer BJ, ”Exploring Intramyocardial Stem Cell Engraftment with Laser Capture Microscopy”. Proceedings of the 2010 BSOM Department of Internal Medicine Research Day, May 2010.

Collins MC, Gunst PR, Moore JL, Virag JI, Muller-Borer BJ, ” Thymosin Beta-4 Provides Enhanced Environment for Human Stem Cell Transplantation”, Proceedings of the International Society for Stem Cell Research, 2010.

Collins MC, Midgette YA, Gunst PR, Muller-Borer BJ, ” Simulated Cardiac Micromechanical Environment Increases Cx43 Expression and Proliferation in Human Mesenchymal Stem Cells”, Proceedings of the International Society for Stem Cell Research, 2010.

Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners):

a.Active Extramural Research Gr ants PI of ECU Subaward (Sole ECU Investigator ), “Mechanisms For Stem Cell Differentiation Into

Cardiac Myocytes” National Heart, Lung and Blood Institute R01 (PI: Margaret Kirby, PhD, Duke University), Annual Direct Costs $357,612 (07/2009 - 06/2011).

Collaborating Investigator , “NO-independent cGMP Regulation of Vascular Remodeling”. National Heart, Lung and Blood Institute R01 (PI: Dave Tulis, PhD, ECU Department of Physiology), Annual Direct Costs $252,325 (04/2010 – 04/2012).

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b. Pending Extramural Research Grants Co-PI , “EphrinA1 Reduces Myocardial Injury”. National Heart, Lung and Blood Institute R21,

(PI: Jitka I. Virag, PhD, ECU Department of Physiology). $275,000. Submitted 07/2011, in review.

c. Funded Intramural Research Grants Principal Investigator, “Stem Cell Engraftment And Trans-Differentiation In A Cardiac Cell

Microenvironment”. University Research Council Grant, The University of North Carolina at Chapel Hill. $4,000 (05/2003 – 04/2005).

Principal Investigator, “A Proteomic Study of Stem Cell Engraftment and Trans-differentiation to a Cardiac Phenotype”. Junior Faculty Development Award, The University of North Carolina at Chapel Hill, Committee on Faculty Research. $5,000 (01/2004 – 12/2004).

Co-PI, “Assessment of Myocardial Cellular Transplantation via Multiple Delivery Modes”, Murray and Sydell Rosenberg Foundation, A Joint Project of The Eastern Carolina Cardiovascular Institute & East Carolina University Brody School of Medicine. $125,000 (01/2005).

Principal I nvestigator, “Role of Thymosin β4 in Stem Cell Engraftment and Myocardial Tissue Regeneration”. Research Development Grant, East Carolina University Division of Research and Graduate Studies. $40,000 (07/2006 – 06/2007).

Collaborating Investigator, “Effects of Cardiopulmonary Bypass on Adult Stem Cell Transplantation”. Research Development Grant, East Carolina University Division of Research and Graduate Studies (PI: Alan P. Kypson, MD, Department of Surgery). $25,000 (07/2006 – 06/2007).

d. Funded Extramural Equipment and Other Grants Co-PI, “Laser Capture Microdissection: Advanced Technology for Biomedical Research”. North

Carolina Biotechnology Center Institutional Development Grant. $163,539 (01/2007). Co-Chair, “Laser Technologies and Applications Group (Laser TAG”). North Carolina

Biotechnology Center (NCBC), NCBC Science & Technology Development Program, Intellectual Exchange Group. Total funding support: $3000 per year, Awarded September 2009, Renewed September 2010.

e. Pending Extramural Development Grants Co-Director, Preparing Biomedical Engineers for Careers in Biotechnology: Developing Outreach

and Collaborative Partnerships. North Carolina Biotechnology Center, $20,000 (08/2011).

Invited research presentations outside ECU: Living Proof: Senior Faces of Research: Documentary video about the benefits of biomedical

research. North Carolina Association for Biomedical Research. October 2005 (interview). Gordon Research Conference in Cardiac Arrhythmia Mechanisms. “Cardiac-Like Calcium

Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”. Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Lemasters JJ, Anderson PAW, Grisham JW, Malouf NN. Beullton, CA, February 2005.

2005 BSOM Department of Internal Medicine Research Day, “Cardiac-Like Calcium Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”. BJ Muller-Borer, WE Cascio, GL Esch, DW Graff , JJ Lemasters, PAW Anderson, JW Grisham, NN Malouf. May 2005 (oral presentation).

78th Scientific Sessions of the American Heart Association. "Calcium-Driven Transcription of a Cardiac Specifying Gene Program in Liver Stem Cells ", Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Aghajanian A, Kim HS, Lemasters JJ, Kim JS, Coleman WB, Grisham JW, Anderson PA, Malouf NN. Dallas, TX, November 16, 2005.

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2006 BSOM Department of Internal Medicine Research Day. “Viability Of Mesenchymal Stem Cells Labeled With Quantum Dot Nano Particles”. Gunst PR, Collins M, Burrows BJ, Kypson AP, Muller-Borer BJ. Greenville, NC, May 2006.

28th IEEE EMBS Annual International Conference. Invited Speaker. Muller-Borer BJ, Cascio WE, Grisham JW, Anderson PAW, Malouf NN, “Acquired Cell-to-Cell Coupling and Cardiac-Like Calcium Oscillations in Adult Stem Cells in a Cardiomyocyte Microenvironment”. New York City, NY, August 2006 (oral presentation).

2006 Scientific Sessions of the American Heart Association. “Long-Term Labeling of Mesenchymal Stem Cells Using Quantum Dot Bioconjugates”. Muller-Borer BJ, Gunst PR, Collins MC, Cascio WE, Kypson AP, Chicago, IL, November 2006 (oral presentation).

2007 BSOM Department of Internal Medicine Research Day, “Mechanisms Controlling the Acquisition of a Cardiac Phenotype by Liver Stem Cells”. Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, NN Malouf. May 2007 (oral presentation).

Sigma Xi – ECU Chapter, Awards Banquet, Invited Speaker, “Mechanisms Controlling the Acquisition of a Cardiac Phenotype by Liver Stem Cells”. Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, NN Malouf. January 2008 (oral presentation).

2008 BSOM Department of Internal Medicine Research Day. “Thymosin 4 Treatment of Human Mesenchymal Stem Cells and Cardiomyocytes”, Collins MC, Gunst, PR, Virag JI, Muller-Borer BJ. Greenville, NC, May 2008.

2009 BSOM Department of Internal Medicine Research Day. “Expression of Cardiogenic Markers in Bone Marrow Derived hMSC’s using Mechanical Strain and Treatment with Growth Factors”, Collins MC, Muller-Borer BJ. Greenville, NC, April 2009.

Keystone Symposia on Molecular and Cellular Biology, Cardiac Disease: Development, Regeneration and Repair (D1). “Thymosin β4 Pretreatment of Human Mesenchymal Stem Cells and Rat Neonatal Cardiomyocytes”. Collins MC, Gunst PR, Byrum G, Virag JI, Muller-Borer BJ, March 17, 2009.

2009 BSOM Department of Internal Medicine Research Day, “Expression of Cardiogenic Markers in Bone Marrow Derived hMSC’s using Mechanical Strain and Treatment with Growth Factors”. Collins MC, Muller-Borer, Greenville, NC, April 2009.

2010 BSOM Department of Internal Medicine Research Day, ”Exploring Intramyocardial Stem Cell Engraftment with Laser Capture Microscopy”, Moore JL ,Collins MC, Virag, JI, Muller-Borer BJ, Greenville, NC, April 2010.

International Society for Stem Cell Research ” Thymosin Beta-4 Provides Enhanced Environment for Human Stem Cell Transplantation”. Collins MC, Gunst PR, Moore JL, Virag JI, Muller-Borer BJ, June 2010.

International Society for Stem Cell Research. “Simulated Cardiac Micromechanical Environment Increases Cx43 Expression and Proliferation in Human Mesenchymal Stem Cells”. Collins MC, Midgette YA, Gunst PR, Muller-Borer BJ, June 2010.

Patents/disclosures/copyrights: Report of Invention -Cell Therapy Infusion Device, GH Tyson, MD, Co-Advisors Alan P.

Kypson, MD, Barbara J. Muller-Borer, Ph.D. Submitted and presented to the East Carolina University’s Office of Technology Transfer and the University Committee on Intellectual Property/Patents, January 2006.

Participation in scholarly collaborations with other universities, laboratories, & centers: PI of ECU Subaward (Sole ECU Investigator ), “Mechanisms For Stem Cell Differentiation Into

Cardiac Myocytes”. National Heart, Lung and Blood Institute R01 (PI: Margaret Kirby, PhD, Duke University), Annual Direct Costs $357,612 (07/2009 - 06/2011).

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Service on related state/national/international boards or committees:Grant Peer Review

American Institute of Biological Sciences, New York State Department of Health and the Empire State Board NYSTEM Program, October 2008

Ad Hoc Peer Review er 1992-1994 IEEE Transactions Engineering in Medicine and Biology 2005 Cardiovascular Research 2005 Journal of Cardiac Electrophysiology2006 - present Engineering in Medicine and Biology Society 2008 – 2009 Molecular Vision 2009 – 2010 Connective Tissue Research

Sigma Xi, Scientific Research Society – East Carolina University Chapter2006 – 2008 Membership Committee2009-2011 Executive Committee Secretary2009 - present Science Café, Steering Committee Member

5.Other:Employment History1979-1982 Human Factors Engineer, New Product Development, Eastman Kodak Co., Rochester, NY. 1985-1986 Masters Candidate and Research Assistant, Curriculum in Biomedical Engineering and

Mathematics, The University of North Carolina at Chapel Hill, Chapel Hill, NC. 1988-1991 Predoctoral Fellow Duke/North Carolina National Science Foundation, Engineering Research

Center for Emerging Cardiovascular Technologies, Curriculum in Biomedical Engineering and Mathematics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1991-1994 Postdoctoral Research Fellow, Department of Internal Medicine/Division of Cardiology, UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1994-1996 NIH Postdoctoral Research Fellow, Department of Internal Medicine/Division of Cardiology, UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1996-1998 Postdoctoral Research Assistant, Department of Internal Medicine/Division of Cardiology, UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1998-2001 Research Associate, Department of Internal Medicine/Division of Cardiology UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

Professional Honors and Awards2009 East Carolina University Chancellor’s Leadership Academy.2009 Bridges Academic Leadership for Women, William and Ida Friday Center for Continuing

Education, The University of North Carolina at Chapel Hill.Professional Societies1997 – present Tau Beta Pi, Engineering Honor Society1990 – present Biomedical Engineering Society1990 – present Institute of Electrical and Electronics Engineers (IEEE)1993 – present American Heart Association1997 – present Cardiac Electrophysiology Society1999 – present Sigma Xi, Scientific Research Society

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2005 – present International Society for Stem Cell Research2005 – present Society of Women Engineers2009 – present International Society for Heart Research

University Committees and Service2005 – present Member, Course Committee, Physiological Proteo-Genomics (PHLY-7704).2006 – present Member, Engineering Advisory Board, Department of Engineering.2006 – present Member, Biomedical Engineering Concentration Planning Committee, Department of

Engineering.2006 – present Member, Brody Women Faculty Committee.2006 – present Program Committee Co-Chair, Stem Cell Interest Group. Co-organize and arrange

monthly meetings and speakers.2006 – present Member, Brody School of Medicine Laser Capture Microdissection Advisory Board.2008 Member, Senior Design Capstone Project Review and Evaluation Committee,

Department of Engineering.2009 Member, Senior Design Capstone Project Review and Evaluation Committee,

Department of Engineering.2009 – 2010 Program Committee Co-Chair, Brody Women Faculty Committee. Co-organized and

arranged monthly meetings and speakers. Co-organized Women in Science and Medicine Conference with the BSOM Office of Academic and Faculty Development, ECU Brody School of Medicine, March 2009.

2009 – 2010 Member, Faculty Search Committee, College of Health and Human Performance, Department of Exercise and Sport Science.

2009 – present Member, Biomedical Engineering Master’s Program Committee, Department of Engineering.

2009 – present Member, Industrial Outreach Committee, Department of Engineering.2009 – present Steering Committee Vice Chair, North Carolina Biotechnology Center Intellectual

Exchange Group for Laser Capture Microdissection (Laser TAG). 2009 – 2011 Elected Member, ECU Faculty Senate Faculty Information Technology Review

Committee, East Carolina University.2010 – 2011 Member, Brody School of Medicine Graduate Studies Committee. 2010 – 2011 Chair Brody Women Faculty Committee.2011 – present Co-Program Director for Interdisciplinary Studies Program in Biological Sciences,

Biomedical Science Graduate Program

Undergraduate Student Advising2008-2009 Instructor, Megan Watkins, Independent Study, “Analysis of Cardiac Calcium

Signaling”, Department of Engineering undergraduate student, ECU College of Technology and Computer Sciences.

2010 – present Mentor/research advisor, Arun Ajmera, recipient of ECU Early Assurance Award 2010, ECU Department of Biology.

Other Teaching Activities2005 Preceptor, Undergraduate, 3 month laboratory rotation. Freshman undergraduate, Amherst

University, Amherst, MA.. 2006 Preceptor, Undergraduate, 3 month laboratory rotation. Park Fellow undergraduate student,

North Carolina State University, Raleigh, NC.2006 Preceptor, Undergraduate, 1 month laboratory rotation. Senior undergraduate in Biomedical

Sciences, University of South Florida, Tampa, FL.2006 Preceptor, High school student, 3 month laboratory rotation. Senior, JH Rose High School,

Greenville, NC.

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2006- 2007 Preceptor, Senior, JH Rose High School Medical Honors program. Greenville, NC.2008 Member, Review Committee, Senior Capstone Project, Department of Engineering, ECU

College of Technology and Computer Sciences.2009 Member, Review Committee, Senior Capstone Project, Department of Engineering, ECU

College of Technology and Computer Sciences.2010 Judge, Graduate Student Oral Presentation, 2010 Department of Internal Medicine Research

Day.2010 Preceptor, High school student ,1 month laboratory rotation. Junior, Chantilly HS, Chantilly,

VA. 2010 – 2011 Preceptor, Senior, D.H. Conley High School Medical Honors program, Greenville, NC.Professional Development

MATLAB Fundamentals and Programming Techniques, Raleigh, NC. April 2003 Lecture and Presentation Skills, Office of Academic and Faculty Development , ECU Brody School

of Medicine. October 2004. Virtual Cell Short Course, University of Connecticut Health Center, Farmington, CT. June 2006. Basic Statistical Skills and Advanced Statistical Skills, Summer Workshop, Center for Faculty

Development, East Carolina University. June 2006. NIH Regional Seminar on Grant Preparation, Research Triangle Park, NC. April 24-26, 2007. International Society of Computerized Electrocardiography, Riverside, CA. May 1 – 5, 2008. Integrative Computational Modeling of the Cardiac Myocyte, NHLBI-JHU T15 Short course on

Myocyte Modeling, Baltimore, MD. August 18 – 22, 2008. East Carolina University Chancellor’s Leadership Academy, Office of Academic Affairs Special

Projects. Jan – May 2009. 9th Annual Coherent – Zeiss Workshop and Multiphoton Users Group Meeting, David H. Murdock

Research Institute, Kannapolis, NC. August, 27-28, 2009. Bridges Academic Leadership for Women, William and Ida Friday Center for Continuing Education,

The University of North Carolina at Chapel Hill, September – November 2009. Medical Education Grand Rounds, Blackboard, BSOM Office of Academic and Faculty

Development, ECU Brody School of Medicine. November 2009. Preparing a Personnel Action Dossier, BSOM Office of Academic and Faculty Development, ECU

Brody School of Medicine, March 2005, October 2009. Accreditation Board for Engineering and Technology (ABET) Faculty Workshop on Sustainable

Assessment Processes – January 2010.Research and Teaching Honors and Awards2005 W. James Metzger, Jr. MD, Brody School of Medicine, Department of Internal Medicine

Research Day, Junior Faculty Presentation Award.2006 Best Drawing Board Invention, “Cell Therapy Infusion Device”, Tyson GH, Co-Mentors Muller-

Borer BJ & Kypson AP. 9th Annual NewEra Cardiac Care Meeting.2007 Best Research Poster, 2007 BSOM Department of Internal Medicine Research Day. “Beating And

Arrested Intramyocardial Injections Are Associated With Significant Mechanical Loss: Implications For Cardiac Cell Transplantation”, Co-Authors Collins MC, Hudson W, deFreitas D, Co-Mentors Muller-Borer BJ & Kypson AP. Greenville, NC.

2006 Faculty Author Recognition Award, East Carolina University, Division of Health Sciences.2007 Faculty Author Recognition Award, East Carolina University, Division of Health Sciences.2008 Sigma Xi, 2008 Helms Award for Faculty Research in Biological Sciences, East Carolina

University Chapter.

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Faculty Information SheetName: Jianchu (Jason) Yao, PhD

1. Rank: Associate Professor - Department of Engineering, East Carolina University (ECU)

2. Degrees: Doctorate of Philosophy Electrical Engineering Dec. 2004

Kansas State University, Manhattan, KS, USA Dissertation: Design of Standards-Based Medical Components and a Plug-and-Play Home Health Monitoring System

Master of Engineering Electrical Engineering July, 1995Shaanxi University of Science and Technology, Shaanxi, China Thesis: On Papermaking Process Expert Control System

Bachelor of Science Electrical Engineering July, 1992Shaanxi University of Science and Technology, Shaanxi, China

3. Teaching Experience related to proposed degree (with emphasis on the past five years)Workload Assignment: 50% teaching, 30% research, 20% service

Associate Professor (Tenured) August 2010Department of Engineering, East Carolina University (ECU), Greenville, NC, 2005 –Present

Develop engineering curriculum, teach electrical engineering related courses, conduct scholarly research, and provide service to the department and the university. Specific duties and accomplishments include:

Started the Department of Engineering (General Engineering) at ECU along with other colleagues, in charge of electrical engineering curriculum and laboratory development. This includes a wide range of duties for structuring new courses from scratch, such as creating course catalog descriptions and course syllabi, identifying course-prerequisites and objectives, developing assessment instruments, planning laboratory space, and researching, purchasing, and maintaining lab equipment;

Develop, teach, and improve four courses, including both lectures and laboratories: ENGR-1014 Introduction to Engineering, ENGR-3014 Circuit Analysis, ENGR-3050 Instrumentation and Controls, and MENG 4350-Electromechanical Systems;

Teach ENGR1012-Engineering Graphics, ENGR 4501-FE Review, COAD 1000-Freshman Seminar; Advised three senior capstone projects; two projects established collaboration with the health science

campus. Started and direct the Bio-Sensors Laboratory (a research lab funded by ECU; currently has two

undergraduate students working in the lab; supported one research associate, one graduate student, and six undergraduate students); conduct technical research in telemedicine, novel application of vital sign signals, and ad-hoc research collaborating with researchers from the ECU medical and health community;

Serve on various committees: Department Assessment Committee, Engineering Core Curriculum Committee, Biomedical Engineering Committee, College International Committee, and University Teaching Grants Committee;

Serve as a reviewer for professional journals, conferences, and federal and local funding agencies Outreach K-12 students to expose them with science, technology, engineering, and mathematics.

Involvements include teaching high school summer programs, leading engineering/technology events, helping with university open houses, etc.

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

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Journal Publications: Crowell, E., Givens, G., Jones, G., Brechtelsbauer, P., & Yao, J. Audiology Telepractice in a

Clinical Environment: A Communication Perspective. Journal of Otology, Rhinology and Laryngology, 120 (7), 441-447.

Howard, E., Williams R., and Yao J. (2010). “Simulations of Carnival Rides and Rube Goldberg Machines for the Visualization of Concepts of Statics and Dynamics,” Engineering Design Graphics Journal, Vol. 74, No. 2.

Yao, J., & Wan, Y. (2010). Improving Computing Efficiency of a Wavelet Method Using ECG as a Biometric Modality. International Journal of Computer and Network Security, 2(1), 15.

Yao, J., Wan, Y., & Givens, G. D. (2009). Using web services to realize remote hearing assessment. Journal of Clinical Monitoring and Computing.

Yao, J., Wan, Y., & Givens, G. (2009a). A Tele-Hearing Diagnosis System Based on Web Services (Abstract). Telemedicine and e-Health, 15(S1), 105.

Yao, J., Sullivan, S., Eckert, C., & Bartlett, E. (2009). An Orthopedic Injection Training Instrument Using Flow Impedance to Indicate Needle Tip Locations. Journal of Clinical Computing and Monitoring, 23( 6).

Yao, J., Givens, G., & Wan, Y. (2009). A Web Services-Based Distributed System with Browser-Client Architecture to Promote tele-audiology Assessment. Telemedicine and e-Health, 15(8,), 777-782.

Yao, J., & Limberis, L. (2009). Coupled-Tanks Level Control: an Effective Course Project and Its Software Design. Computer in Education Journal 19(4).

Yao, J., Limberis, L., Williams, R., & Howard, E. (2009). A Efficient PID Control Teaching Module with LabVIEW Simulation. Computer in Education Journal, 19(2), 30-41.

Yao, J., & Warren, S. (2005a). Applying the ISO/IEEE 11073 Standards to Wearable Home Health Monitoring Systems. Journal of Clinical Monitoring and Computing, 19(6), 427-436.

Yao, J., Schmitz, R., & Warren, S. (2005). A Wearable Point-of-Care System for Home Use that Incorporates Plug-and-Play and Wireless Standards. IEEE Transaction on Information Technology in Biomedicine, 9(3), 363-371.

Warren, S., Yao, J., & Lebak, J. (2005). Applying Emerging Interoperability Standards to Wearable Point-of-Care Systems (Abstract). Telemedicine and e-Health, 11(2), 193.

Yao, J., Ding, X., Zhan, Q., & Zhang, Q. (2000). On Task-based Directional Manipulability of Redundant Robot. Robots (Chinese), 22 (6).

Yao, J. (1999). Application of Single-Chipped Microcomputer on Automatic Package Machine. Machinery and Electronics (Chinese).

Yao, J., & Wang, M. (1998). Boiler Water Lever Control System in Sodium Recycling Process. Journal of Northwest Institute of Light Industry (Chinese).

Sun, Y., Yao, J., Fei, J., & Wang, M. (1998). Application of GENIE on Pulp-Making Process. Journal of Northwest Institute of Light Industry (Chinese).

Refereed Conference Proceedings: Li, Jiting Zheng, Ruoyin Zhang, Yuru Yao, Jianchu. iHandRehab: An interactive hand exoskeleton

for active and passive rehabilitation, presented at the 2011 IEEE International Conference on Rehabilitation Robotics (ICORR), Zurich, Switzerland, June 29 2011-July 1, 2011.

Yao, J., Limberis, L., & Warren, S. (2010). A Ubiquitous Laboratory Model to Enhance Learning in Electronics Courses Offered by Two Universities with Dissimilar Curricula. Presented at the 2010 Frontier in Education, Washington, DC.

Warren, S., & Yao, J. (2010). Updates to a Mobile Circuits-and-Signals Learning Kit that Incorporates a USB Data Acquisition Unit. Presented at the 2010 Frontier in Education, Washington, DC.

Warren, S., & Yao, J. (2010, June 20-23). Portable Cyber-Laboratories for Electrical Engineering Education. Paper presented at the 2010 Annual ASEE Conf., Louisville, KY, USA.

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Howard, W., Williams, R., & Yao, J. (2009, October 12-18). Simulations of Carnival Rides and Rube Goldberg Machines for the Visualization of Concepts of Statics and Dynamics. Paper presented at the ASEE Engineering Design Graphics Division’s Mid Year Conference, Erie, PA.

Yao, J., Wan, Y., & Givens, G. (2009b, Sept. 3-6). Design of a Web Services Based System for Remote Hearing Diagnosis. Paper presented at the the 31st IEEE-EMBS Conf., Minneapolis, MN USA.

Yao, J., & Barttlet, E. (2009, June 14-17). Design and Prototype of an Injection Location Indicator: A Senior Capstone Project and Multi-Party Partnership. Paper presented at the 2009 Annual American Society of Engineering Education Conference, Austin, TX.

Yao, J., & Wan, Y. (2008, June 1-3, 2008). A Wavelet Method for Biometric Identification Using Wearable ECG Sensors. Paper presented at the the 5th International Workshop on Wearable and Implantable Body Sensor Networks (BSN 2008), Hong Kong, China.

Yao, J., & Limberis, L. (2008, June 22-25). A Project-Driven Approach to Teaching Controls in a General Engineering Program. Paper presented at the 2008 Annual American Society of Engineering Education Conference, Pittsburg, MA, USA.

Wan, Y., & Yao, J. (2008, October 22-24). A Neural Network to Identify Human Subjects with Electrocardiogram Signals. Paper presented at the the World Congress on Engineering and Computer Science (WCECS) 2008 of International Association of Engineers (IAENG), San Francisco, CA.

Yao, J., Sun, X., & Wan, Y. (2007). A Pilot Study on Using Derivatives of Photoplethysmographic Signals as a Biometric Identifier. Paper presented at the the 29th IEEE-EMBS Conf., Lyon, France.

Yao, J., Limberis, L., & Kauffman, P. (2007, June 21-24). An Electrical Systems Course in a General Engineering Program: Experience and Lessons. Paper presented at the Annual American Society of Engineering Education Conference, Hawaii, USA.

Wan, Y., Sun, X., & Yao, J. (2007, October 17-20). Design of a Photoplethysmographic Sensor for Biometric Identification,. Paper presented at the 2007 International Conference on Control, Automation and Systems, Seoul, Korea.

Sullivan, S., Williams, R., Howard, E., & Yao, J. (2007, June 21-24). Identifying the Content of a General Engineering Program Using Benchmarking and the Fundamentals of Engineering Examination. Paper presented at the 2007 Annual ASEE Conf, Hawaii, USA.

Yao, J., Warren, S., & Simmons, S. (2006, April, 2-4). Ease of Use Considerations for Point-of-Care Devices in Home Environments. Paper presented at the Conf. of Decentralization of Healthcare via Distributed Diagnosis and Home Healthcare (D2H2), Arlington, VA, USA.

Yao, J., & Lunsford, P. (2006, June 18-21). Laboratory from the First Day: an Efficient Method to Convey Electrical Concepts to Engineering Students. Paper presented at the 2006 Annual American Society of Engineering Education Chicago, IL.

Yao, J., Dieck, G., Dixon, G., Howard, E., McLawhorn, S., Williams, R., et al. (2006). ‘Who is the Biggest Pirate?’ Design, Implementation, and Result of a Robotics Competition for General Engineering Freshmen. Paper presented at the 2006 Annual American Society of Engineering Education Conference, Chicago, IL.

Warren, S., Lebak, J., & Yao, J. (2006, April, 2-4). Lessons Learned from Applying Interoperability and Information Exchange Standards to a Wearable Point-of-Care System. Paper presented at the Conf. of Decentralization of Healthcare via Distributed Diagnosis and Home Healthcare (D2H2), Arlington, VA, USA.

Yao, J., & Warren, S. (2005b, September 1-4). A Short Study to Assess the Potential of Independent Component Analysis for Motion Artifact Separation in Wearable Pulse Oximeter Signals. Paper presented at the the 27th IEEE EMBS Conf, Shanghai, China.

Yao, J., & Warren, S. (2005). Stimulating Student Learning with a Novel ‘In House’ Pulse Oximeter Design. Paper presented at the 2005 Annual Conference and Exposition, American Society for Engineering Education.

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Warren, S., Lebak, J., Yao, J., Creekmore, J., Milenkovic, A., & Jovanov, E. (2005, September 1-4). Interoperability and Security in Wireless Body Area Network Infrastructures. Paper presented at the the 27th IEEE EMBS Conf., Shanghai, China.

Yao, J., & Warren, S. (2004, Sept). A Novel Algorithm to Separate Motion Artifacts from Photoplethysmographic Signal Obtained with a Reflectance Pulse Oximeter. Paper presented at the the 4th Joint EMBS-BMES Conf., San Francisco, CA, USA.

Warren, S., Yao, J., Schmitz, R., & Lebak, J. (2004, Sept). Reconfigurable Point-of-Care Systems Designed with Interoperability Standards. Paper presented at the the 26th IEEE EMBS Conf, San Francisco, CA, USA.

Lebak, J., Yao, J., & Warren, S. (2004). HL7-Compliant Healthcare Information System for Home Monitoring. Paper presented at the the 26th IEEE EMBS Conf., San Francisco, CA, USA.

Yao, J., Schmitz, R., & Warren, S. (2003, Sept). A Wearable Standards-Based Point-of-Care System for Home Use. Paper presented at the the 3rd Joint EMBS-BMES Conf., Cancun, Mexico.

Warren, S., Yao, J., Schmitz, R., & Nagl, L. (2003, Sept.). Wearable Telemonitoring Systems Designed with Interoperability in Mind. Paper presented at the the 25th IEEE EMBS Conf, Cancun, Mexico.

Lebak, J., Yao, J., & Warren, S. (2003, Sept). Implementation of a Standards-Based Pulse Oximeter on a Wearable Embedded Platform. Paper presented at the the 25th IEEE EMBS Conf., Cancun, Mexico.

Yao, J., & Warren, S. (2002). Design of a Plug-and-Play Pulse Oximeter. Paper presented at the Second Joint Meeting of BMES and EMBS.

Warren, S., Yao, J., & Barnes, G. E. (2002, Oct). Wearable Sensors and Component-based design for Home Health Care. Paper presented at the the 2nd Joint EMBS-BMES Conf. , Houston, TX, USA.

Book Chapters Jianchu Yao, Yongbo Wan and Steve. Warren. Biometric Applications of One-Dimensional

Physiological Signals – Electrocardiograms. Recent Application in Biometrics. ISBN 978-953-307-488-7. Editors: Jucheng Yang and Norman Poh. InTech Publisher.

Wan, Y., & Yao, J. (2008). Human Identification with Electrocardiogram Signals: a Neural Network Approach IAENG Transactions on Engineering Technologies Volume II - Special Edition of the World Congress on Engineering and Computer Science 2008. ISBN: 978-0-7354-0663-6. American Institute of Physics, 2009.

Yao, J. (2008). Work Harder and Work Smarter to Land a Faculty Job. In Z. J. Pei (Ed.), Tips on getting an academic position. ISBN: 978-0-557-05363-6, Lulu.com, 2009.

Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners):

National Science Foundation. “Portable Cyber-Laboratories: Virtual Instruments and Affordable Prototyping Kits to Enhance Learning and Improve Access to Electrical Engineering Education”, $88,100. Role: PI. Collaborate with Kansas State University.

North Carolina Department of Transportation, “Fleet Management Criteria: Depreciated Life, Disposal Point & Utilization,” $95,334. Role: Co-PI. PI: Dr. Paul Kauffmann.

East Carolina University Office of Technology Transfer, Development of a Location Identification Device for Orthopedic Injections (Phase II), $1,500. Role: PI.

East Carolina University Office of Technology Transfer, Development of a Location Identification Device for Orthopedic Injections (Phase I), $6,000. Capstone project fund. Role: Faculty Advisor.

East Carolina University College of Allied Health, Development of a Web Services Based Distributed System for Tele-hearing Diagnosis, $25,000.

East Carolina University Start-up Award, Realizing Self-Help Healthcare through Pervasive Sensing and Intelligent Human-Device Interactions, $120,000. Role: PI.

Presentations/Talks

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“A Web Services-based Distributed System with Browser-Client Architecture to Promote Tele-audiology Assessments”, ECU, Business of Healthcare Symposium 2010.

“Conduct Scholar Research in a Developing Undergraduate Program,” East Carolina University Engineering Advisory Board Annual Meeting, October, 27, 2009.

“A Web-services Based Distributed Tele-audiology System,” East Carolina University Innovation Expo, Brody School of Medicine, April 2, 2009.

“A Web-services Based Distributed Tele-audiology System,” East Carolina University International Scholars Symposium, April 1, 2009.

“Design of PnP Home Health Monitoring Systems and Their Standards,” Chinese Academy Sciences, Shenzhen Advanced Technology Institute, Shenzhen, China. June 4, 2008.

“Development of Home Health Monitoring Systems,” Beijing University of Posts and Telecommunications, Beijing, China. May 15, 2008.

“Use a Personal Electronic Nurse to Promote Self Care,” 1st Healthcare Mini Research Symposium, Nursing School, East Carolina University. November 9, 2006.

“Plug-and-Play Home Health Monitoring Systems Using Wearable, Standards-Based Medical Components,” Northwest Polytechnic University and Shaanxi University of Science and Technology, Xi’an, China. June 7, 2006.

“Design and Implementation of Standards-Based Point-of-care System for Home Use,” 8th Research Forum, Kansas State University, April 4, 2003, Manhattan, KS.

“Veterinary Telemonitoring for Disease Prevention in Cattle Herds,” Cattlemen’s Day, Kansas State University, March 7, 2003, Manhattan, KS.

Patents/disclosures/copyrights: “Internet-based Multi-user Diagnostic Hearing Assessment Systems Having Client-server

Architecture with User-based Access Levels for Secure Data Exchange,” Provisional patent, 2009-2010; currently filing PCT (Patent Cooperative Treat) to protect intellectual property rights cross the world. Co-inventor: Gregg Givens

An Online Calculation Toolbox for Health Care,” Disclosed on July 29, 2011. Co-inventor: Zhibin Huang.

“Systems integrating virtual instruments and virtual reality to support ubiquitous laboratory learning,” disclosed on August 8, 2011.

Service on related state/national/international boards or committees: East Carolina University Graduate Faculty East Carolina University Intellectual Property/Patent Committee: ’10 East Carolina University Teaching Grants Committee: ’07-’09. Secretary ’09 College of Technology and Computer Science International Committee: ’08-’09 Department of Engineering: Engineering Core Committee, Biomedical Engineering Concentration

Committee, Assessment Committee North Carolina Summer Ventures in Math and Science (’06-’10) Science Olympia Tournament (’09, ’10) East Carolina University Engineering/Technology Day (’06-’09) East Carolina University Open House (’05-’09) Outreach: Chinese New Year’s Traditionals presentation to 1st graders in W. H. Robinson Elementary

School, 2009

5. Other:PREVIOUS PROFESSIONAL EXPERIENCE:

Research Assistant Medical Component Design Laboratory Kansas State University, Manhattan, KS 2001– 2005

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Designed, developed, and prototyped wearable, standards-based medical sensors and wireless body networks to construct plug-and-play health monitoring systems with an open architecture. Developed and tested a novel motion artifact reduction algorithm for wearable pulse oximeters.Accomplishments/duties include: Designed medical components in three categories (base station, data logger, and sensor unit) by

integrating Bluetooth with the Medical Information Bus; Prototyped a desktop base station with LabVIEW interfaces; a wearable, low-power data logger with

larger memory; two wearable, microcontroller sensor units (pulse oximeter and ECG); and a weight scale with temperature and humidity measuring capability;

Congregated the medical components into a plug-and-play, interoperable, scalable, dynamical health-monitoring system with an open architecture; built Bluetooth wireless body area networks and local area networks; and achieved device plug-and-play performance without human interventions;

Developed and tested a novel bio-signal process algorithm that improves signal-to-noise ratio by separating motion artifacts from desired PPG signal and calculates both venous and arterial oxygen saturation, surpassing its traditional alternatives that can only compute the arterial oxygen saturation.

Research Engineer Robotics Research InstituteBeijing, China 1998–2000

Researched redundant robot kinetic control and tasks-based directional manipulability to maximize path planning with given tasks; built motion control units for modular robots which can work either as a stand-alone controller or under a host controller with commands received over a RS-232 serial port.

Controls Engineer and Group Leader Institute of Microcomputer Applications, Shaanxi, China 1995–1998 Design, developed, and installed SCADA (supervisory control and data acquisition) systems for industrial processes, primarily focusing on manufacturing processes in pulp & paper industry. Managed two projects with 4 members – assigned work to members, planned timelines, and examined daily progress.Responsibilities include:

Analyzed target processes and documented system specifications; Evaluated, selected, and integrated components (sensors, controllers, and actuators); Designed control algorithms and human-machine interfaces; Tuned control parameters (e.g., PID); Performed field installation, debugging, and testing; Oversaw two contract projects valued at $150,000.

Representative projects: Designed and developed SCADA systems for the following pulp & paper processes:

Sodium recycling, Linqing Pulp & Paper Inc. Shangdong, Jan.1997–July, 1998Pulp plant, Zhongwei Pulp & Paper Inc. Ningxia, Sep.1996–Apr. 1997 Paper basis weight & moisture, Dongying Papermaking Co., Shangdong, Jan. 1995–Sep. 1996Pressurized Headbox, Shouguang Pulp & Paper Inc., Shangdong, July 1995–Feb.1996

Implemented sequence-control for automatic package machines.

HONORS AND AWARDS The Oppenheimer Award: 64th ASEE Engineering Design Graphics Division’s Mid Year Conference,

2009 (coauthor: William Howard, Rick Williams) Treasured Pirate Award 2009 for Display of Creativity and Initiative, East Carolina University International Travel Award to present papers at Hong Kong and Shenzhen, China, ECU International

Affairs Office, 2008.

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Best Paper Nominee, Experimentation and Laboratory-Oriented Studies, ASEE 2008, (coauthor: Loren Limberis)

Elevated to IEEE Senior Member in 2007 New Faculty Research Award, 2006. East Carolina University Graduate Travel Award, Kansas NSF EPSCoR, 2004 Graduate Travel Award, Kansas State University Graduate Student Council, 2003

REVIEWER: IEEE Transactions on Instrumentation and Measurement Sensors China National Science Foundation proposal review, 2011 National Science Foundation proposal review panelist, twice in 2006 Technology Interface Journal International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’07-’09) American Society of Engineering Education Annual Conference (ASEE ’06-’09) International IEEE Conference on Industrial Informatics (INDIN 2006) International IEEE Conference on Control, Automation and Systems (ICCAS 2007)

PROFESSIONAL DEVELOPMENT: “Conducting Rigorous Research in Engineering Research” Workshop, Golden, CO (4 days, August,

2010) ABET Accreditation Assessment Training Workshop, Baltimore, MD (one day, February, 2007) MIT Leadership Skill Workshop, Boston, MT (two days, July, 2007) VaNTH ERC “How People Learn Engineering” Workshop, Nashville, Tennessee (two days, April,

2006)

MEMBERSHIPS

2001 – Present Institute of Electrical and Electronics Engineers (IEEE) (S’01-M’05-S’07)2009 – Present American Telemedicine Association 2002 – Present IEEE Engineering in Medicine and Biology Society2005 – Present American Society of Engineering Education2003 IEEE Instrumentation and Measurement Society

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Faculty Information SheetName: Loren Limberis

1. Rank: Assistant Professor of Engineering - East Carolina University

2. Degrees: University of Utah, Department of Bioengineering, 2006 Ph.D. in BioengineeringDissertation title: Toward Kinesin-Powered Chemomechanical Devices

University of Utah, Department of Electrical and Computer Engineering, 1992 B.S. Electrical Engineering

3.Teaching Experience: Workload Assignment: 45% teaching, 30% research, 25% service

Assistant Professor of Engineering Fall 2006—present East Carolina University

Assistant Professor of Electrical and Biomedical Engineering Fall 2002 – Spring 2006The College of New Jersey

Teaching Assistant, Department of Bioengineering Fall 1998Biopolymer CharacterizationUniversity of Utah

Teaching Assistant, Department of Biology Fall 1993Human PhysiologyUniversity of Utah

Courses:BIOE 3000 Bioprocess Engineering Systems (with laboratory)BIOE 3016 Engineering Applications in MicrobiologyBIOE 4010 Bioprocess Separation Engineering (Developed and delivered 4-week laboratory)BIOE 4020 Bioprocess Plant Design, Simulation, and AnalysisBIOL 7345 Cell Motility (Guest lecturer)COAD 1000 Engineering Freshmen ExperienceENGR 1014 Introduction to Engineering (with laboratory)ENGR 3014 Circuit Analysis (with laboratory)ENGR 3050 Instrumentation and Control Systems (with laboratory)ENGR 3902 Undergraduate Research in EngineeringENGR 3903 Undergraduate Research in Engineering ENGR 4010 and 4020 Senior Capstone (Faculty advisor)ITEC 2010 Introduction to Industry and Technology (Guest lecturer)

4.Scholarly & Professional Activities related to proposed degree (with emphasis on the past five

years)Publications/Scholarly Activity related to proposed degree:

Yao, J. and Limberis, L. (2009) Coupled-Tanks Level Control: An Effective Course Project and Its Software Design. Computers in Education Journal. 19(4):53-62.

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Yao, J, Limberis, L, Williams, R, Howard, E. (2009) An Efficient PID Control Teaching Module with LabVIEW Simulation. Computers in Education Journal. 19(2):30-41.

Limberis, L., Magda, J.J., and Stewart, R.J. (2001) Polarized alignment and surface immobilization of microtubules for kinesin-powered nanodevices. Nano Letters 1:277-280.

Limberis, L. and Stewart, R.J. (2000) Toward kinesin-powered microdevices. Nanotechnology 11:47-51.

Ho, C-H., Limberis, L., Caldwell, K.D., and Stewart, R.J. (1998) A metal-chelating pluronic for immobilization of histidine-tagged proteins at interfaces: immobilization of firefly luciferase on polystyrene beads. Langmuir 14:3889-3894.

Invited Book Chapters:Stewart, R.J. and Limberis, L., (2007) Engineering a Molecular Railroad, In: NanoBioTechnology: BioInspired device materials of the future; Editors: Oded Shoseyov and Ilan Levy, Humana Press, NJ.

Professional Employment:Research Assistant, Biomolecular Engineering Laboratory 1995 – 2001 University of Utah, Department of Bioengineering

Research Associate 2000 – 2001 Allvivo of Birmingham, Alabama, University of Utah

Research Analyst 1994 – 1995Southwest Research InstituteHill Air Force Base, Clearfield, Utah

Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners):

2010 – Limberis, L. (PI) & Hu, X-H. “Engineering photoreceptor-controlled aggregation and disaggregation of nanoparticle suspensions as a platform for biotechnology devices,” North Carolina Biotechnology Center Biotechnology Research Grant (BRG), ($82,500).

2009 – Williams, R. (PI), Aswell, J., Limberis, L., Amico, L., Picard, G., Umphlett, R., Yarley, D., “Integration of Hands‐on Short Courses into a Bioprocess Engineering Curriculum,” North Carolina Biotechnology Center Education Enhancement Grant (EEG), ($59,533).

2009 – Limberis, L. (PI) & Millard, S., “Project Photo-Link: Photoreversible Control of Nanoparticle Aggregation and Disaggregation as a Platform for Biotechnology Devices,” Office of Technology Transfer, East Carolina University, ($5,000).

2008 - Limberis, L. (PI), Stellwag, E., Bier, M., & Hu, X., "Development of a Biohybrid DNA Separation Device Featuring Fast and Linear Separation with Single Base Pair Resolution," Research Development Award (RDA) Program at ECU, ECU Research Development Award (RDA) Program, ( $19,820).

2008 - Williams, R. (PI), Klein, S., Limberis, L., & Sullivan, S., "Design and Development of Educational Modules for Bioprocess Engineering," GOV-National Science Foundation (NSF), ( $136,480).

Small Grants VaNTH – “How People Learn Engineering” Workshop Scholarship 2007The College of New Jersey – Support of Scholarly Activity 2006

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3 credit course releaseThe College of New Jersey – Support of Scholarly Activity 2005 3 credit course releaseBiobased Engineering Fellowship, The Whitaker Foundation 1996National Institutes of Health Research Training Grant 1995

Invited research presentations outside ECU: Nanoengineering with Motor Proteins, Guest Lecturer BIOL 7345 Cell Motility (Spring 2010) Introduction to Biotechnology, Guest Lecturer ITEC 2010 Introduction to Industry and Technology

(Fall 2007; Spring 2008) Nanosystem Engineering with Kinesin Motor Proteins. Invited presentation at Science at the

Starlight; North Carolina Biotechnology Center and Sigma Xi The Scientific Research Society, Greenville, North Carolina, December 2007.

Nanoengineering with Motor Proteins, Professional Engineers of North Carolina, Greenville, NC, February 2007

Nanoengineering with Motor Proteins, The College of New Jersey, Ewing, NJ, March 2005 Introduction to Biotechnology, The College of New Jersey, Ewing, NJ, March 2005 Ultrasonic Bioinstrumentation, The College of New Jersey, Ewing, NJ, March 2005 Review of Mathematics (Fundamentals of Engineering Review Course) The College of New Jersey,

Ewing, NJ, February 2005 Review of Chemistry (Fundamentals of Engineering Review Course) The College of New Jersey,

Ewing, NJ, February 2005 What is Bioengineering?, The College of New Jersey, Ewing, NJ, October 2004 Toward Kinesin-Powered Chemomechanical Devices, The College of New Jersey, Ewing, NJ,

December 2003 The Emerging Field of Biomedical Engineering: Opportunities for all Engineering Disciplines The

College of New Jersey, Ewing, NJ, October 2003 Toward Kinesin-Powered Chemomechanical Devices, The College of New Jersey, Ewing, NJ,

October 2002 Kinesin-Based Active Microdevices, Department of Bioengineering, University of Utah, Salt Lake

City, UT, October 2000 Overview of Microtubule Motor Proteins; In Vitro Kinesin Motility, Department of Bioengineering,

University of Utah, Salt Lake City, UT, November 1999

Patents/disclosures/copyrights:Metal-Chelating Surfactant. U.S. Patent 6,087,452—July 11, 2000. Inventors Russell Stewart, Karin D. Caldwell, Chih-hu Ho, and Loren Limberis

Service on related state/national/international boards or committees:Reviewer

IEEE Transactions on Advanced PackagingSpecial section on Packaging for Micro/Nano-Scale Systems

ASEE Annual Conference ProceedingsNSF Career AwardsECU Undergraduate Research and Creative Activities grant reviewer

Faculty Advisor 2009 – presentISPE ECU Student Chapter

Student Activities Coordinator 2002 – 2006IEEE Princeton/Central New Jersey Section (Region 1)

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Includes Princeton University, The College of New Jersey, Rutgers University, Middlesex County College, and DeVry University

East Carolina University and Engineering Department Committees:Departmental Bioprocess Engineering Committee (Chairman) (2006-present)Departmental Assessment Committee (2006-present)Departmental Biomedical Engineering Curriculum Committee (2006-2009)Departmental Capstone Committee (2008-present)University Undergraduate Research and Creative Activities Committee (2006-present)

5. Other:AffiliationsInternational Society for Pharmaceutical Engineering (ISPE)American Society Engineering Education (ASEE)

Graduate Research Committee MembershipTess Byers (2008-2009) Master’s Thesis Committee Member (Paul Gemperline Chair) – Research involves slurry sampling, measurement, and chemometric methods of evaluation.

Undergraduate Research Projects and Senior Theses Supervised:DSM Water Conservation (2010-2011) Faculty AdvisorDesign and Optimization of Firefly Luciferase Production, Purification, and Characterization at the

Benchtop Bioreactor Scale (2008-2009) Faculty AdvisorIEEE Micro-mouse (2004-2006) Co-advisorThe 2005-2006 team won first place in the 2006 IEEE Region 1 Micro-mouse competition in Maine and was awarded $700The 2004-2005 team won first place in the 2005 IEEE Region 1 Micro-mouse competition in Buffalo, NY and was awarded $1000.Home Theater Calibration System (2003-04) Principal AdvisorProsthetic Hand (2002-2004) Co-advisorUse of emerging technologies for a distributed HVAC system in Armstrong Hall (2002-03) Co-

Advisor

Professional Workshops Attended that are Related to Teaching: VaNTH workshop on “How People Learn Engineering”, February 2007, Vanderbilt University

Council on Undergraduate Research workshop titled “Institutionalizing Undergraduate Research”, October 2004, The College of New Jersey

Week-long NSF sponsored workshop titled “How to Engineer Engineering Education”, July 2004, Bucknell University

AwardsCentennial Award for Excellence (Spirit) – East Carolina University 2010

Refereed Conference Proceedings:

Yao, J., Limberis, L., and Warren, S., (2010) Work in Progress – A ubiquitous laboratory model to enhance learning in electronics courses offered by two universities with dissimilar curricula. Frontiers in Education Annual Conference.

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Williams, R., Klein, S., Limberis, L., and Sullivan, S., (2009) Design and Development of Educational Modules for Bioprocess Engineering. American Society for Engineering Education (ASEE) Annual Conference Proceedings.

Klein, S., Williams, R., Limberis, L., and Sullivan, S., (2009) Bioprocess Engineering Curriculum Development and Assessment. American Society for Engineering Education (ASEE) Annual Conference Proceedings.

Yao, J, Limberis, L. (2008) A Project-Driven Approach to Teaching Controls in a General Engineering Program. American Society for Engineering Education (ASEE) Annual Conference Proceedings.

Yao, J., Limberis L., and Kauffmann, P. (2007) An Electrical Systems Course in a General Engineering Program; American Society for Engineering Education (ASEE) Annual Conference Proceeding.

Sepahpour, B. Clark, E. and Limberis, L. (2004) Modular Lumped Mass Experiment, Experimentation & Laboratory Oriented Studies; American Society for Engineering Education (ASEE) Annual Conference Proceedings. Limberis, L. and Stewart, R.J. (1998) Biological transport in a microfabricated device: active immunochromatography with motorized antibodies; in Microfluidic Devices and Systems, A. Bruno Frazier, Chong Hyuk Ahn, Editors, Proceedings of SPIE Vol. 3515, 66-75.

Conference Abstracts and Presentations:Klein, S., Williams, R., Limberis, L., and Sullivan, S., (2009) Bioprocess Engineering Curriculum Development and Assessment—ASEE Annual National Conference, June 2009, Austin, TX.

Sepahpour, B. Clark, E. and Limberis, L. Modular Lumped Mass Experiment. Experimentation & Laboratory Oriented Studies—ASEE Annual National Conference, June 2004, Salt Lake City, UT.

Limberis, L., Ho, C-H., and Stewart, R.J. Kinesin-powered microchemomechanical systems(MCMS). Seventh Foresight Conference on Molecular Nanotechnology, October 1999, SantaClara, CA.

Limberis, L. and Stewart R.J. Biological transport in a microfabricated device: active immunochromatography with motorized antibodies. Microfluidic Devices and Systems—SPIE Proceedings Conference September 1998, Santa Clara, CA.

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Faculty Information SheetName: RICHARD R. WILLIAMS

1. Rank: Associate Professor, Engineering East Carolina University

2. Degrees:Ph.D. Mechanical Engineering, Auburn University, 2002M.S. Mechanical Engineering, Georgia Institute of Technology, 1983B. Mechanical Engineering, Georgia Institute of Technology, 1982

3. Teaching Experience related to proposed degree (with emphasis on the past five years)Workload Assignment: 60% teaching, 20% research, 20% service

East Carolina University, Greenville, NC Assistant Professor, Engineering, 2005-Present

Auburn University, Auburn, AL Associate Director, Materials Processing Center, 2003-2005 Auburn University, Associate Research Professor, 2002-2005 Auburn University, Graduate Research Assistant, 1999-2002

United States Navy US Naval Academy, Instructor, Naval Systems Engineering, 1987 - 1989 Submarine Officer, 1983-1989

Courses:East Carolina UniversityCOAD 1000, Freshman SeminarICEE 1010, Integrated Collaborative Engineering I (course coordinator)ICEE 1020, Integrated Collaborative Engineering IIENGR 1012, Engineering Graphics (course coordinator)ENGR 1014, Introduction to Engineering (course coordinator)ENGR 2010, Computer Applications in EngineeringENGR 2070, Materials and ProcessesENGR 3024, Mechanics of MaterialsENGR 4010, Capstone DesignBIOE 4010, Bioprocess Separations Engineering (course coordinator)ENGR 4503, Special Topics: Advanced Thermal SystemsENGR 4503, Special Topics: Mechanics of MaterialsENGR 4503, Special Topics: RoboticsENGR 4503, Special Topics: Robotic SensorsSummer Ventures (NC School of Science and Mathematics)

Auburn UniversityMECH 4250, Comprehensive Design IIMECH 3030, Fluid MechanicsENGR 2200, Introduction to Thermodynamics, Fluids, and Heat Transfer

United States Naval AcademyEN 100, Naval Propulsion Systems

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Georgia Institute of TechnologyME 3055, Mechanical Measurements (Lab TA)

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

Publications/Scholarly Activity related to proposed degree:Journal Articles Williams, R., Howard, W., & Martin, S. (accepted 2010). Composite Sandwich Structures with

Rapid Prototyped Cores. Rapid Prototyping Journal. Howard, W., Williams, R., & Yao, J. (accepted 2010). Simulations of Carnival Rides and Rube

Goldberg Machines for the Visualization of Concepts of Statics and Dynamics. Engineering Design Graphics Journal.

Yao, J., Limberis, L., Williams, R., & Howard, W. (2009). An Efficient PID Control Teaching Module with Labview Simulation. Computers in Education Journal, 19(2), 30-41.

Williams, R., Shao, R., & Overfelt, R. (2008). The Flowability of Fine Powders in Reduced Gravity Conditions. Granular Matter, 10(2), 139 - 144.

Shao, R., Williams, R., & Overfelt, R. (2006). The Fluidization Behavior of Fine Powders in Reduced Gravity Conditions. Journal of Thermophysics and Heat Transfer, 20(3), 371-375.

Williams, R. & Harris, D. (2006). A Device and Technique to Measure the Heat Transfer Limit of a Planar Heat Pipe Wick. Experimental Thermal and Fluid Science, 30(3), 277-284.

Williams, R. & Harris, D. (2005). Heat Transfer Limit of Step Graded Metal Felt Heat Pipe Wicks. Int. Nat. J. of Heat and Mass Transfer, 48(2), 293-305.

Williams, R. & Harris, D. (2003). Cross-Plane and In-Plane Porous Properties Measurements of Thin Metal Felts: Applications in Heat Pipes. Experimental Thermal and Fluid Science, 27(3), 227-235.

BooksMusto, J. Howard, W., & Williams, R. (2009). Engineering Computations: An Introduction Using MATLAB and Excel. Boston: McGraw-Hill, 2009.

Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners): Williams, R. (PI), Aswell, M., & Limberis L. (2010). Integration of Hands-on Short Courses into a

Bioprocess Engineering Curriculum, North Carolina Biotechnology Center, $40,323, awarded. Williams, R. (PI), Limberis, L., Klein, S., and Sullivan, S. (2008). The Design and Development of

Educational Modules for Bioprocess Engineering. NSF CCLI, $136,480, awarded. Howard, W., (PI), Bosse, M., & Williams, R. (2008). Engineering Explorations: A Course Using

Engineering Methods and Tools for Math and Science Education Majors. NSF CCLI, $105,630, rejected.

Howard, W., (PI), Bosse, M., Williams, R, & James, L. (2007). Engineering Explorations: A Course for Education Majors to Model the Application of Mathematics and Science in Engineering. NSF CCLI, $148,891, rejected.

Howard, W., (PI), Micklow, G., Dixon, E., & Williams, R. (2006). Acquisition of Rapid Prototyping Equipment for Basic Research and Integration into the New Undergraduate Systems Engineering Program. NSF MRI, $400,000, rejected at the University level.

Williams, R. & Howard, W. (2006). Composites Innovation. ECU Division of Research and Graduate Studies, $130,145, awarded.

Williams, R. (2005). Rapid Prototyping Vacuum Casting. ECU Faculty Senate Research/Creative Activities Grant, $22,218, rejected.

Williams, R. (2005). Auburn University Equipment Transfer: $150,000, transferred capital equipment from Auburn University to ECU to maintain research collaboration.

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Invited research presentations outside ECU: Williams, R. & Howard, W. (2010). The Assessment Driven Evolution of a First-Year Program.

Proceedings of the 2010 ASEE Annual Conference and Exposition, Louisville, KY. Howard, W., Williams, R., & Yao, J. (2009). Simulations of Carnival Rides and Rube Goldberg

Machines for the Visualization of Concepts of Statics and Dynamics. 64th Annual Midyear Conference of the Engineering Graphics Division of ASEE, Erie. PA.

Williams, R., Klein, S., Limberis, L., & Sullivan, S. (2009). Design and Development of Educational Modules for Bioprocess Engineering. Proceedings of the 2009 ASEE Annual Conference and Exposition, Austin, TX.

Klein, S., Williams, R., Limberis, L., & Sullivan, S. (2009). Bioprocess Engineering Curriculum Development and Assessment. Proceedings of the 2009 ASEE Annual Conference and Exposition, Austin, TX.

Howard, W., Williams, R., & Agarwala, R. (2008). Solid Modeling as a Visualization Tool for High School Math and Science Topics. Proceedings of ASEE EDGD 63rd Mid-Year Conference, San Diego, CA.

Brown, E., Williams, R., & Bedenbaugh. P. (2008). An Example of Vertical Integration in and Engineering Curriculum. Proceedings of the 2008 ASEE Southeast Section Conference, Memphis, TN.

Williams, R.& Howard, W. (2007). A Versatile and Economical Apparatus for Experiments in Statics,” Proceedings of the 2007 ASEE Annual Conference and Exposition, Honolulu, HI.

Howard, W. & Williams, R. (2007). An Introductory Engineering Design Project Using Finite Element Analysis and Rapid Prototyping. Proceedings of the 2007 ASEE Annual Conference and Exposition, Honolulu, HI.

Sullivan, S., Williams, R., Howard, W., Yao, J., & Kauffmann, P. (2007). Identifying the Content of an Engineering Program using Benchmarking and the Fundamentals of Engineering Examination. Proceedings of the 2007 ASEE Annual Conference and Exposition, Honolulu, HI.

Howard, E., Williams, R., & Prantil, V. (2007). Work-in-Progress - Incorporating Realistic Problems into a Finite Element Analysis Course. Proceedings of the 2007 IEEE Frontiers in Education Conference, Milwaukee, WI.

Yao, J., Dixon, E., Howard, W., Williams, R., Williamson, K., Dieck, G., & McLawhorn, S. (2006). “Who is the Biggest Pirate?” Design, Implementation and Result of a Robotics Competition for General Engineering Freshman. Proceedings of the 2006 ASEE Annual Conference and Exposition, Chicago, IL.

Williams, R., Shao, R., & Overfelt, R. (2006). The Flowability of Fine Powders in Reduced Gravity Conditions. Proceedings of the Fifth World Congress on Particle Technology, Orlando, FL.

Williams, R., Shao, R., & Overfelt, R. (2005). The Fluidization of Cohesive Powders in Reduced Gravity Conditions. Workshop on Granular Materials in Lunar and Martian Exploration, NASA, JFK Space Center, FL.

Overfelt, R., Williams, R., Bakhtiyarov, S., & Wang, D. (2003). Future Needs and Opportunities in Thermophysics from a Materials Engineer's Perspective. Proceedings of the 27th International Thermal Conductivity Conference, Knoxville, TN.

Williams, R., Flenniken, J., & Harris, D., (2002). The Characterization of Micro-fibrous Materials for the Use as Heat Pipe Wicks. Proceedings of SECTAM XXI Conference, Orlando, FL.

Overfelt, R., Crumpler, M., Cobb, H., Langley, R., Strom, B., & Williams, R. (2001). Vulcan-TP: Industrial Thermophysical Property Measurements in Space. Proceedings of the International Space Station Utilization Conference, Titusville, FL.

Patents/disclosures/copyrights: Abbott, III, J. & Williams, R., (1999). Method for Coating Fibers. United States Patent 5974837.

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Williams, R. (1999). Vertical Vaporizer for Halide-free, Silicon-containing Compounds. United States Patent 5938853.

Williams, R. (1997). Method of Providing Vaporized Halide-free, Silicon-containing Compounds. United States Patent 5632797.

Amos, L., Chludzinski, P., Leoni, H., Watson, J., & Williams, R. (1994). Method and Apparatus for Coating Optical Waveguide Fibers. United States Patent 5366527.

Service on related state/national/international boards or committees: University Research Council: 2008-2009 College Curriculum Committee: 2009-present College Laboratory Committee: 2005-2008 College Technology Consultant Search Committee: 2006 College Lab Supervisor Search Committee: 2006 Engineering Department Curriculum Committee (chair): 2006-present Engineering Department Admissions Committee: 2006-present Engineering-Math Committee: 2008-present Engineering Department Bioprocess Concentration Committee: 2006-present Engineering Department Mechanical Concentration Committee: 2008-2009 Engineering Department K-12 Outreach Committee: 2006 -2008 Engineering Department Major Grants Committee: 2006-2007 Engineering Department Software Committee: 2005-2006 Engineering Department Chair Search Committee: 2006

5. Other:Professional ExperienceCorning Inc., Wilmington, NC· Section Supervisor, Eagle Engineering, 1995 – 1999· Equipment Engineer/Project Engineer/Sr. Project Engineer, 1989 – 1995

Theses/Dissertations“An Investigation of the Use of Step-Graded Metal Felt Wicks to Improve Heat Pipe Performance,”

Doctor of Philosophy; Supervisor: Dr. Daniel K. Harris

Society Memberships and Professional Honors and AwardsRegistered Professional EngineerAmerican Society of Mechanical EngineersAmerican Society of Engineering EducationReviewer: IEEE Transactions on Electronic Packaging ManufacturingReviewer: Metallurgical and Materials TransactionsReviewer: Journal of Porous MaterialsReviewer: American Society of Engineering EducationFaculty Advisor, Sol of Auburn, Auburn University’s Solar Car TeamTau Beta PiPi Tau SigmaCorning, Inc., Outstanding Contributor Award, Division Cash Award (4 times)

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Faculty Information SheetName: Stephanie M. George

1. Rank: Assistant Professor of Engineering - East Carolina University

2. Degrees: Ph.D. Biomedical Engineering, August 2008 Georgia Institute of Technology, Atlanta, Georgia Emory University, Atlanta, GeorgiaClassification of Portal Hypertension and Cirrhosis using Magnetic Resonance Imaging- Using MRI to classify and quantify the hemodynamics of the portal venous system as relating to portal hypertension and cirrhosis.

Advisor: Don P. Giddens, PhD, Dean of Engineering

B.S. Engineering Science and Mechanics, May 2002 Virginia Polytechnic Institute and State University, Blacksburg, Virginia

3. Teaching Experience related to proposed degree (with emphasis on the past five years):

Workload Assignment: 50% teaching. 40% research, 10% service

Assistant Professor of Engineering, August 2010 to PresentCollege of Technology and Computer ScienceEast Carolina University, Greenville, NC

Teaching undergraduate courses, ENGR 1012 Designing and implementing junior and senior level courses for Biomedical Concentration, BIME 3000 and BIME 4030

Problem Based Learning Across the Curriculum Fellowship, Fall 2007-Spring 2009Center for Science Education, Emory University

Designed, implemented and assessed problem based learning cases at a City of Atlanta High School

Gandy/Diaz Teaching Fellowship, Fall 2007, Spring 2008, Spring 2010, Summer 2010Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech

Designed, implemented and assessed cases in an undergraduate biomedical engineering problem based learning class, BMED 1300

Developed and gave lecture on mathematical modeling Facilitated small groups of students as they solved cases

Engineering Science I, Graduate, Spring 2005Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University

Held review and homework help sessions Graded papers

Problem Based Learning II, Undergraduate BMED 2300, Fall 2004Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech

Facilitated small group of students and assessed research, teamwork, and communication skills

T.A.T.T.O Training, Emory University, Fall 2003

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Teacher Assistant training

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

Publications/Scholarly Activity related to proposed degree: S.M. George, D.R. Martin and D.P. Giddens. Contribution of Superior Mesenteric Vein Flow to

the Right and Left Lobes of the Liver Using CFD. In Preparation. S.M. George, D.R. Martin and D.P. Giddens. Characterizing Normal Portal Vein Hemodynamics

using Magnetic Resonance Imaging and Computational Fluid Dynamics. In Preparation. S.M. George, D.R. Martin and D.P. Giddens. Hemodynamic Changes in Patients with Chronic Liver

Disease Using Magnetic Resonance Imaging and Computational Fluid Dynamics. In Preparation.

S.M. George, D.R. Martin and D.P. Giddens. Portal Vein Contribution to the Right and Left Lobes of the Liver Using MRI and CFD. 6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore, IFMBE Proceedings, 2010, Volume 31, Part 2, 473-476.

Y.Yang, S. George, D. Martin, A. Tannenbaum, and D. Giddens.  3D Modeling ofPatient-Specific Geometries of Portal Veins Using MR Images.   In Proceedings ofthe 28th IEEE EMBS Annual International Conference, pages 5290-5293, 2006.

Invited research presentations outside ECU: S.M. George, B. Fasse and K.S. Lee. Acquiring Experimental Design Skills Through Problem-

Based Learning. 2010 Biomedical Engineering Society Annual Meeting. Austin, Texas. October 2010.

S.M. George, D.R. Martin and D.P. Giddens. Portal Vein Contribution to the Right and Left Lobes of the Liver Using MRI and CFD. 6th World Congress of Biomechanics (WCB 2010). Singapore, August 2010.

S. M. George, D. R. Martin, and D. P. Giddens. Computational Analysis of Flow in the Portal Vein of Normal Subjects and Patients Using MRI and CFD. Electronic Poster Presentation at the International Society for Magnetic Resonance in Medicine 2010 Annual Meeting. Stockholm, Sweden. May 2010.

S.M. George, D.R. Martin, D.P. Giddens. Contribution of Superior Mesenteric Vein Flow to the Right and Left Lobes of the Liver Using CFD. Proceedings of the ASME 2008 Summer Bioengineering Conference, Lake Tahoe, CA. June 2009.

S. M. George, D. R. Martin, and D. P. Giddens. Hemodynamic Investigation of Flow in the Normal Portal Vein. Student Poster Competition. Proceedings of the ASME 2008 Summer Bioengineering Conference. Marco Island, Florida. June 2008.

S. M. George, P. Sharma, D. R. Martin, and D. P. Giddens. Geometry and Flow in the Portal Vein of Normal Subjects and Patients using Magnetic Resonance Imaging. Electronic Poster Presentation at the International Society for Magnetic Resonance in Medicine 2008 Annual Meeting. Toronto, Ontario. May 2008.

S.M. George, P. Sharma, Y. Yang, Y. Gao, D.R. Martin and D.P. Giddens. Investigation Of Geometry And Flow In The Portal Vein Using Magnetic Resonance Imaging Poster Presentation at Biomedical Engineering Society 2007 Annual Meeting. Hollywood, CA. Sept. 2007.

S.M. George, D.R. Martin and D.P. Giddens. A Computational Model of Hemodynamics in the Portal Vein. Poster Presentation at Biomedical Engineering Society 2007 Annual Meeting. Hollywood, CA. Sept. 2007.

S.M. George. Medieval Women Mystics and the Question of Anorexia. Conference on Gender Studies, Radford University, Radford, Virginia, March 2001

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5. Other Research Experience:

Comparison and Statistical Validation of Cerebral Flow Results Obtained Using Phase Contrast MRA and Computational Flow Dynamics in an In Vitro Cerebral Aneurysm Model. August 2009 to Present Frank Tong, M.D., Emory University, Atlanta, GA

Developed computational models of two cerebral aneurysm models Validated and compared the in vitro measurements with computational results

Patient Outcome Assessment Comparative Evaluation: Rabia Balkhi Hospital, Afghanistan, January 2009 to October 2009 (unpaid)Denise Giles, MPH, WHO Collaborating Center in Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia

Comparison of YR2003, YR2005, and YR2008 Patient Outcome Assessment data using epidemiologic and industrial systems engineering methods.

Improvement of maternal and newborn services in a low resource setting. Calculation of risk profiles and modeling of risk through health services areas.

Post-Doctoral Fellowship, August 2008 to August 2010Diego Martin, M.D., PhD and Don Giddens, PhD, Georgia Tech and Emory University, Atlanta, Georgia

Investigated clinical significance of hemodynamic parameters to diagnosis, progression and monitoring of chronic liver disease.

Used CFD to determine source of the right liver lobe’s blood supply

Effect of Problem Based Learning on Undergraduate Students, July 2008 to Present Barbara Fasse, PhD, Dept. of Biomedical Engineering, Georgia Tech, Atlanta, Georgia

Created scoring system for pre- and post-Problem Based Learning assessments Quantitatively measured experimental design knowledge gained from PBL

Doctoral Student, August 2002 to August 2008Don Giddens, PhD, Georgia Tech and Emory University, Atlanta, Georgia

Optimized data acquisition for portal vein geometry and flow measurements using MRI and phase contrast-MR

Analyzed normal subject and patient flow data to determine potential parameters that may change due to disease

Created four computational model of the blood flow within the portal vein

Investigating the Use of Resin, Summer 2003 Robert Taylor, M.D., PhD Emory University, Atlanta, Georgia

Researched different types of resin and tested them as a means of fixing tissues. Constructed polymerization chamber, cut histological sections using microtome and

conducted tissue staining.

Imaging Aortic Wall Compliance using MRI and High Speed Camera Imaging, Spring 2003 John Oshinski, PhD, Emory University, Atlanta, Georgia

Measured the area changes of a phantom model using MRI and high speed camera imaging and compared the results.

Co-op Student, Jan 2000 to May 2000, Aug 2000 to Jan 2001, May 2001 to Aug 2001 DuPont Advanced Fiber Systems- Kevlar, Richmond, Virginia

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Hypothesized and tested design differences in parts to determine potential causes of process instability

Developed and implemented Uptime model for use in monitoring, auditing, and upgrading Kevlar performance

Learned and applied Six Sigma tools and methodology in polymer isolation, pump reliability, and fiber materials handling

Activities:Founding Member of Georgia Tech’s Parent’s Network 2008-2010Graduate Student Representative to Georgia Tech’s Childcare Task Force ’05-‘07Worked with Georgia Tech’s Women’s Resource Center on graduate student issuesCertified Water Aerobics and Pre/Post Natal Fitness Instructor

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Faculty Information Sheet

Name: Chad Bossetti

1. Rank: Assistant Professor - Dept. of Engineering, East Carolina University

2. Degrees:Duke University Ph.D., Dept. of Biomedical EngineeringDurham, NC Experimental Electrophysiology Laboratory, Mar. 2009

Design and Evaluation of a Transcutaneous EnergyTransfer System. Advisor: Patrick D. Wolf, Ph.D.

University of Colorado B.S., Electrical and Computer EngineeringColorado Springs May 2002, Special Honors

3. Teaching Experience related to proposed degree (with emphasis on the past five years):

Workload Assignment: 50% teaching, 40% research, 10% service

Assistant Professor Dept. of Engineering, East Carolina UniversityBiomedical Instrumentation. August 2010-Present

Teacher Dept. of Biomedical Engineering, Duke University.Instructor for Signals and Systems course, Fall 2007.Responsible for all aspects of the course, includingselection of topics, bi-weekly lectures, and supervision of agrader and teaching assistant.

Kaplan, Inc., 2001-2002.Prepared and presented lectures for ACT, SAT, and GREtest preparation courses.

Teaching Assistant Dept. of Biomedical Engineering, Duke University. Biomedical Signals and Measurements, Fall 2002 and Spring

2003. Included lab and project supervision.

Electrophysiology, Spring 2004. Included wet lab supervision.

Mentor Pratt School of Engineering, Duke University.Provided project guidance and technical expertise to a group of three undergraduates enrolled in the Devices for the Disabled course. Spring 2006. Project was a wireless battery-recharging unit.

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

Publications/Scholarly Activity related to proposed degree:Peer-Reviewed Journal PublicationsM. Rizk, C.A. Bossetti, T.A. Jochum, S.H. Callender, M.A.L. Nicolelis, D.A. Turner, and P.D. Wolf, “A fully implantable 96-channel neural data acquisition system.” Journal ofNeural Engineering, vol. 6, no. 2, Apr. 2009.

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C.A. Bossetti, M.J. Birdno, W.M. Grill, “Analysis of the quasi-static approximation forcalculating potentials generated by neural stimulation.” Journal of Neural Engineering, vol. 5, no. 1, pp. 44-53, Mar 2008.

C.A. Bossetti, J.M. Carmena, M.A.L. Nicolelis, P.D. Wolf, “Transmission latencies in a telemetry-linked, brain-machine interface.” IEEE Transactions on BiomedicalEngineering, vol. 51, no. 6, pp. 919-924, Jun 2004.

Conference Papers/AbstractsM.J. Birdno, C.A. Bossetti, W.M. Grill, “Validity of the quasi-static assumption forcalculating potentials generated in neural stimulation.” Neural Interfaces Workshop,National Institute of Neurological Disorders and Stroke, Bethesda, MD, Aug 2006.

C.A. Bossetti, T.A. Jochum, S.H. Callender, P.D. Wolf, “A transcutaneous energytransfer system for brain-machine interface applications.” Biomedical EngineeringSociety, Baltimore, MD, Oct 2005.

J. Morizio, D.S. Won, I. Obeid, C.A. Bossetti, M.A.L. Nicolelis, P.D. Wolf, “16-Channel neural pre-conditioner device,” 1st Int IEEE BMES Conf on Neural Engineering. Capri Island, Italy. Mar 2003.

5. Other: RESEARCH EXPERIENCE

Dissertation Project Switching power supply design for a transcutaneous energy transfer system (wireless power supply). Hardware design and VHDL interface for an implantable thermometry system. FDA compliance testing for tissue temperature rise from an implanted medical device. FCC compliancetesting of specific absorption rate for EM dosimetry.

Neural Stimulation A computational modeling study of the potential developed in a tissue volume conductor as a result of stimulation. A comparison was made between the solution to the inhomogeneous scalar Helmholtz wave equation and classic quasi-static simplifications. Stimulus efficacy was quantified for a model neuron in a frequency-dependent dielectric medium. Dr. Warren Grill, Duke University.

RESEARCH INTERESTS:Transcutaneous Energy Transfer: Design of switch-mode power supplies; coil designand radiated electromagnetic fields; tissue temperature rise and specific absorption rate.

Field Potential Modeling in Tissue: Effects of dielectric tissue properties onelectromagnetic wave propagation.

Implanted Medical Devices: neural recording and stimulation systems; visual and cortical motor prosthesis; and low- and high-voltage implanted cardiac systems.

Electromagnetic Field Measurement and Calibration: Instrumentation for measurementof the high-strength static magnetic fields, low-strength AC magnetic fields, and RFelectromagnetic fields associated with magnetic resonance imaging (MRI).

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PROFESSIONAL EXPERIENCESt. Jude Medical Sylmar, CA, July 2008-July 2010 Senior Hardware Design

Engineer, Cardiac Rhythm Management Division Lead Engineer, characterization and verification of implanted device MRI compatibility.

American Journal Durham, NC, Aug 2006-Jan 2007.Experts Independent contract editor

LSI Logic, Inc. Colorado Springs, CO, 2000Competitive Analysis Group, Summer Internship

U. S. Air Force 90th Space Wing, F.E. Warren AFB, Cheyenne, WY,1995-1998, Honorable Discharge Strategic Communications Maintenance, Electronic computer and switching system specialist Department of Defense Top Secret/Single-Scope Background Investigation, 1995-1998

AWARDS AND HONORS:♦Colorado Scholars Award, 2000-2002♦Outstanding Student Engineer, Colorado Engineering Counsel, 2002♦Eta Kappa Nu

PROFESSIONAL DEVELOPMENT:Introduction to College Teaching, Duke University. A course focusing on approaches to teaching, development of learning objectives, and syllabus and course design.

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Faculty Information Sheet

Name: Stephanie T. Sullivan, PhD, CPIM

1. Rank: Teaching Instructor, Department of Engineering East Carolina University

2. Degrees:B.S.M.E., 1990, Aerospace & Mechanical Engineering, University of Notre Dame, Notre Dame, INM.S., 1996, Chemical Engineering, North Carolina State University, Raleigh, NCDoctoral Student, 2006-Present, Chemical & Biomolecular Engineering, North Carolina State University

3. Teaching Experience related to proposed degree (with emphasis on the past five years):

Workload Assignment: 75% teaching, 15% research, 10% service

Teaching Instructor, Department of Engineering, East Carolina University 2006-present

Courses:BIOE 4000; ENGR 2050; ITEC 3000, 4150, 4250, 4350, 4550; ICEE 1020, 3300

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

Publications/Scholarly Activity related to proposed degree:Yao, J., Sullivan, S. T., Eckert, C., & Bartlett, E., (2009). An Orthopedic Injection Training Instrument Using Flow Impedance to Indicate Needle Tip Locations. Journal of Clinical Monitoring and Computing 23:347-353.

Hall, C., Sullivan, S. T., Kauffmann , P. J., Batts, D. & Long, J., (2009) "Are there Gender Differences in Factors Influencing Career Considerations?" American Journal of Educational Studies vol 2, no1, pp 23-38.

Sullivan, S. T., Eckert, C., Cannon, M. & Khan, S. A., (2009) Functional gels of whey protein and pullulan blends, 2009 Proceedings, The International Symposium on Food Rheology and Structure, Zurich, Switzerland.

Williams, R. R.; Klein, S.; Sullivan, S.; Limberis, L.; (2009) ASEE 2009 Annual Conference, June 2009, Bioprocess Engineering Curriculum Development and Assessment.

Williams, R. R.; Sullivan, S.; Klein, S.; Limberis, L.; (2009) ASEE 2009 Annual Conference, June 2009, Design and Development of Educational Modules for Bioprocess Engineering.

Sullivan, S. T., Khan, S. A., & Eissa, A. S. (2008). Whey Proteins: Functionality and Foaming under Acidic Conditions. In C. Onwulata & P. Huth (Eds.), Whey Processing, Functionality and Health Benefits (Institute of Food Technologists Series) (pp. 99-132). : Wiley-Blackwell.

Sullivan, Stephanie; Hall, Cathy; Kauffmann, Paul; Batts, David; Long, Jeremy; (2008) Influences on Female Interest in Pursuit of STEM Fields in Higher Education, 2008 American Institute of Higher Education Conference Proceedings.

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Sullivan, Stephanie T.; Williams, Rick; Howard, William E.; Yao, Jason; Kauffmann, Paul. (2007) Identifying the content of an Engineering program using benchmarking and the Fundamentals of Engineering examination; 2007 ASEE Annual Conference Proceedings.

Kabin J.A.; Tolstedt S.L.; Sáez A.E.; Grant C.S.; Carbonell R.G. (1998). Removal of Organic Films from Rotating Disks Using Aqueous Solutions of Nonionic Surfactants: Effect of Surfactant Molecular Structure. Journal of Colloid and Interface Science, vol 206, no 1, pp 102-111.

Service on related state/national/international boards or committees:

East Carolina University Service NSF ITEST Grant, Biomechanics Curriculum Coordinator, Spring 2007 – Present. Biomedical Engineering Concentration Curriculum Committee, Fall 2007 – Present. Bioprocess Engineering Concentration Curriculum Committee, Fall 2006 – Present. College of Technology & Computer Science Distance Education Task Force, Spring 2007. Engineering Management Curriculum Committee, Fall 2006 – Spring 2007. Engineering K-12 Outreach Committee, Fall 2006 – Present.

5. Other:Engineering Course Coordinator: ENGR 3300, BIOE 4000, BIME 4030

INDUSTRY EXPERIENCEMerck & Co., Inc., Wilson, NCContract Operations, March - August 2006Operations Planning, August 2003 – March 2006Quality Assurance, Manufacturing Quality Operations, July 2001 – July 2003Engineer/Scientist, Pharmaceutical Technical Operations, September 1998 – July 2001

PCS Phosphate & Co., Inc., Aurora, NC Production Engineer, Diammonium Phosphate Granulation Plants, July 1997 – September 1998Maintenance Engineer, Phosphoric Acid Manufacturing, November 1996 - June 1997

Stone & Webster Engineering Corporation, Houston, TXFluid Systems Engineer, July 1992 – August 1993

Amoco Oil Company, Whiting, IN & Texas City, TXProject Engineer, June 1990 – June 1992

Professional Exams/Certifications American Production and Inventory Control Society (APICS) Certification in Production and Inventory

Management (CPIM), 2006. Engineer-In-Training, (Fundamentals of Engineering) State of Indiana, 1990.

Honors & Awards Nanofibers for the 3rd Millenium: A Summit of the World’s Leaders in Nanofibers. August 2010. 2nd

place in poster competition. NSF CCLI Grant Co-PI, Award No. 0737198, Design and Development of Educational Modules for

Bioprocess Engineering, CCLI-Phase 1. North Carolina Future Program Partner, FoodMASTER, 2008 Science Education Partnership Award,

National Center for Research Resources, National Institutes of Health

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Guest Faculty, UNC Chapel Hill School of Pharmacy graduate level course PPES 180 “Pharmaceutical Research, Development & Marketing,” Pharmaceutical Manufacturing, 2000 – 2004.

National Academy of Engineering Summit on Women in Engineering, Washington D.C., 1999. Duke University Materials Science & Mechanical Engineering Research Fellowship, 1996. Poster Presentation, M.S. thesis research. International Symposium on Surfactants in Solution “Micelles,

Microemulsions and Monolayers: Quarter Century Progress and New Horizons" at University of Florida, (300 researchers from 25 countries in attendance), 1995.

Patricia Roberts Harris Fellow, North Carolina State University, 1994-1995. Glenna R. Joyce Scholar, University of Notre Dame, full 4-year academic scholarship, 1986-1990. National Science Foundation Research Experience for Undergraduates (REU) appointment, University of

Notre Dame, 1989.

American Institute of Chemical Engineers (AIChE) Leadership Societal Impact Operating Council Member, 2003 – 2004. Process Development Division Topical Proceedings Chair, AIChE Annual Meeting, 2003 & 2004 Chair, AIChE Women’s Initiatives Committee (WIC), 2001. Chair, AIChE Annual Meeting WIC technical session, 2001 Co-Chair, AIChE Annual Meeting WIC Inaugural technical session, 2000 Vice Chair, 2000; Secretary, 1999; Visibility Subcommittee Chair, AIChE WIC, 1998.

COLLABORATORSCollaborators: Gerald Micklow, Tarek Abdel-Salam, William Howard, Paul Kauffmann, Tom Fink, Cathy Hall, Melani Duffrin, East Carolina University; Saad Khan, North Carolina State University; G. Donald Allen, Texas A&M University. Graduate Advisors: Saad Khan (PhD), Christine Grant, Ruben Carbonell (MS), North Carolina State University

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