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For Toxic Samples:. . For Non-Toxic Samples:. . Ceriodaphnia dubia Reproduction. Ceriodaphnia dubia Reproduction. - PowerPoint PPT Presentation
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Replicate Control 6% 12% 25% 50% 100%
#1 X X X X X X
#2 X X X X X X
#3 X X X X X X
#4 X X X X X X
#5 X X X X X X
#6 X X X X X X
#7 X X X X X X
#8 X X X X X X
#9 X X X X X X
#10 X X X X X X
Average - - - - - -
For Toxic Samples:
0% 6% 12% 25% 50% 100%
For Non-Toxic Samples:
0% 6% 12% 25% 50% 100%
DMR-QAStudy
# ofLabs
MedianValue
2.5th
Percentile97.5th
Percentile
#12 103 20.0 1.60 50.0
#13 124 25.0 6.25 50.0
#14 147 25.0 6.25 50.0
#15 147 25.0 6.25 50.0
#16 140 25.0 6.25 50.0
Ceriodaphnia dubia Reproduction
Test NOEC IC-25 Result1 25 31.9 Fail2 100 100 Pass3 100 100 Pass4 100 100 Pass5 50 37.9 Fail6 100 100 Pass7 100 100 Pass8 100 12.1 Fail9 100 100 Pass10 100 100 Pass11 50 100 Fail12 100 100 Pass13 n/a n/a Invalid14 25 50.8 Fail15 n/a n/a Invalid16 6.25 36.7 Fail
REFERENCE TOXICANT
METHOD BLANK
TEST FAILS
Accurate:True Positive
Inaccurate: False Positive
TEST PASSES
Inaccurate: False Negative
Accurate: True Negative
# of Type-1 Errors Observed in 80
Statistical Analyses
Probability of ObservingEXACTLY as many
Type-1 Errors
Probability of ObservingAT LEAST as many
Type-1 Errors
0 in 300 .00002% ---
1 in 300 .0003% 99.99998%
2 in 300 .003% 99.9997%
3 in 300 .01% 99.997%
4 in 300 0.1% 99.98%
5 in 300 0.2% 99.93%
6 in 300 0.4% 99.77%
7 in 300 0.9% 99.34%
8 in 300 1.8% 98.4%
9 in 300 3.1% 96.6%
10 in 300 4.7% 93.5%
11 in 300 6.6% 88.8%
12 in 300 8.3% 82.2%
13 in 300 9.7% 73.9%
14 in 300 10.5% 64.2%
15 in 300 10.5% 53.7%
16 in 300 9.9% 43.2%
17 in 300 8.7% 33.3%
18 in 300 7.1% 24.7%
19 in 300 5.6% 17.5%
20 in 300 4.1% 11.9%
21+ in 300 --- 7.8%
Ceriodaphnia dubia Reproduction
Test NOEC IC25 Status
1 100 100 Pass
2 100 100 Pass
3 100 100 Pass
4 100 100 Pass
5 100 100 Pass
6 100 100 Pass
7 100 100 Pass
8 100 100 Pass
9 100 100 Pass
10 100 100 Pass
11 100 100 Pass
12 100 100 Pass
13 100 100 Pass
Test NOEC IC25 Status
14 25 31.9 Fail
15 50 69.8 Fail
16 50 46.5 Fail
17 50 37.9 Fail
18 50 100 Fail
19 25 50.8 Fail
20 6.25 36.7 Fail
21 100 11.6 Fail
22 100 12.1 Fail
23 6.25 3.3 Invalid
24 100 43.9 Invalid
