From Science to Innovation to Wellbeing

– Why am I here

– What matters to healthcare

– What matters to MNEs selling to healthcare

– Canadian platform for accelerated product development in digital health

– Case Study: Neurotech

Agenda

3. Board Director: Health Quality Innovation Collaborative, SensoryTech, ICFITT/Russia-Canada Tech Transfer

4. Entrepreneur: Cogniciti, Konona Health Tech

1. Researcher: Moscow University, Livermore National Lab, California

2. Investor: GATX Capital, San Francisco, MaRS Venture Group, Toronto

Build great companies Develop a vibrant innovation hub

Strengthen Canada’s global innovation brand

Because the future matters

VENTURES

Accelerate and grow entrepreneur-driven,

high-impact ventures

from startup to

scale/impact.

SYSTEMS

Scale and diffuse innovation through

collaborative initiatives

that open markets and

create new solutions.

TALENT

Attract and develop Canadian innovators,

and equip them with the

skills, tools, intelligence

and networks they need

to thrive in the

innovation economy.

Pg 5

Transform clinical “know-how” of the leading Memory Research center into a consumer

health web app

Konona Health Tech’s mission is to lower health care costs by investing in innovative, consumer-centered solutions

WHAT MATTERS TO HEALTHCARE Not a technology fix, change in practice!

9

The value of devices no longer resides only in the product itself. Today the value is in medtech companies’ ability to provide information and services to customers, to solve larger problems such as improving outcomes, operating room efficiency, reducing length of hospital stays, and avoiding unnecessary readmissions

Challenge:

Pre-Diagnosis

Interventions

Treatment Decision

Parameters

Health Outcomes

Patient – Physician Dialogue

How to Achieve Shared Accountability Along Patient Journey?

New models of care are focusing on “staying left” Technology helps healthcare professional to target attention

Market Appetite For

• Digital devices that capture clinically valuable data for improving healthcare workflows

• Connect into existing IT ecosystem

• “Accountable Tech”, pay for itself based on diagnostic, therapeutic, or other outcomes

• De-skilling, not a technology fix but expanding access to care or scope of services

WHAT MATTERS TO MNE SELLING TO HEALTHCARE

New Business Models

The market is demanding a new approach to innovation in medtech

The value of devices no longer resides only in the product itself. Today the value is in medtech companies’ ability to provide information and services to customers, to solve larger problems such as improving outcomes, operating room efficiency, reducing length of hospital stays, and avoiding unnecessary readmissions. Source: PWC Global Medtech

CEO survey, 2013

Lessons from innovation practitioners: successful innovations involve at least 4 types of innovation

Source: Larry Kelley, Monitor

Nimble innovative teams create massive value for large players in the healthcare sector

Canada: innovation launch pad

• Living Lab

• Single Payer System

• R&D incentives

Canada

• Dynamic market

• New payment models

United States

Health Transformation

2020

EU

BRIC

A start-up is a temporary organization designed to search for a sustainable business model. Steve Blank

Research

Applied University Chairs

R&D clusters

Imaging, Neurotech etc.

Innovation

Federal SR&D tax credits

Health Sciences Centres

MaRS

EXCITE

Development

IRAP funding to companies

Canada Infoway and eHealth Funding for local implementations

Thought Leadership in Clinical Evaluative Science

Nurturing entrepreneurial

ventures in health is a key

focus of Federal and Provincial

governments in Canada

Entrepreneur

18

Neuroimaging

Clinical

Genomics

Proteomics

Other

Ce

reb

ral P

alsy

Au

tism

AD

HD

Epile

psy

Oth

er

Bra

in D

iso

rde

rs

Dat

a M

od

alit

ies

Disease-themed, multidisciplinary collaborations collecting multiple modalities of

data and integrating into clinic

VitaSound Audio Inc

Patented Neuro-Compensator is a ‘best-in-class’ technology, which significantly improves the listening experience by improving the clarity, crispness and naturalness of sound.

NeuroVox Inc Uses electroencephalography (EEG) to measure brain response relevant to mental functions of concern in brain injury/concussion.

Avertus Epilepsy Technologies Inc The SMART Headset (Seizure Monitoring at the Right Time) is a monitoring and detection system, provide an objective measure of seizure occurrence to assess drug efficacy.

Neurotech Cluster

Konona Health designed as Corporate Garage

Healthcare is increasingly shifting away from hospitals

and providers with consumers and patients taking more

responsibility and interest for their own care. We build

companies that support this transition.

– Products that keep consumers healthy and

self-sufficient. Focus on devices and software

promoting cognitive and sensory health, and

providing for self-regulation and the

convenience of connected care.

– Products for both payers and providers that

help them direct attention to at-risk populations

and allocate resources wisely. Focus on data

visualization, analytics, and solutions that

expand revenue opportunities and reach into

the community.

• Target 25% IRR

• Investment horizon: 5 years

19

Strategic Location Hamilton-Niagara, ON, Canada healthcare community (pop. 1.2 million) has a track record of pioneering Health IT implementations and has already deployed an integrated IT system across the region. Leadership of the local health authority is enthusiastic about working together with innovators to generate the evidence necessary to support clinical and business process re-design and to create feasible revenue models.

A company’s choice of markets and M&A is 4x more important that outperforming in its markets.

McKinsey &Co, 2007

ISO 13485:2003

Design, Innovation, Med-tech acceleration firm: multidisciplinary team: Strategists, Engineering, Industrial Design, QA RA, Prototyping, Manufacturing, ISO 13485, Med-Tech startup savvy Integrated set of services and infrastructure designed to identify and bridge gaps, incubate and accelerate Med-tech companies by focusing on building their technology and product to commercial grade and market readiness Core knowledge: Strategy; increasing valuation, managing risk. Execution; Med device development, Industrial Design. Manufacturing; NPI and design for scale-ability

Konona Health Tech Capabilities

EXCITE moves the Health Technology Assessment and Comparative evaluation from a punitive gate to a product optimization tool in partnership with a leading healthcare

customer, Ontario health system.

Provides medtech companies with valuable evidence and business requirements — key information for regulatory reviews, reimbursement reviews and

competitive positioning

My values guide me: intellectual curiosity,

hard work, honesty, humility, empathy and

transparency

Veronika Litinski

Chief Executive Officer

Konona Health Tech

M: 647.309.9043

W: www.kononahealth.com

E: veronika@kononahealth.com

@VL_MaRS

BLOG:http://www.marsdd.com/tag/veronika-litinski/