GCB Symposium 2020 Thursday, January 30, 2020, 08h30‒17h00, followed by an Apéro Department of Chemistry and Biochemistry, Freiestrasse 3, 3012 Bern, and Department of Physiology, Bühlplatz 5, 3012 Bern (Morning Sessions)

08h30–09h45 Talks I & Poster Flash I 09h45–10h15 Coffee Break 10h15–11h30 Talks II & Poster Flash II

11h30–13h00 Poster Session A 12h30–14h00 Lunch Break (two groups)

13h30–15h00 Poster Session B 15h00–15h30 Coffee Break 15h30–16h00 GCB Award for Best PhD Thesis 16h00–17h00 Keynote Lecture:

Prof. Dr. Sylviane Muller School of Biotechnology, University of Strasbourg, France «Mechanism-Guided Novel Therapies for Treating Inflammatory Diseases»

17h00– Closing Remarks Apéro

Guests welcome

https://www.gcb.unibe.ch/gcbsymp/

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Talks I:Biological SystemsLocation:PYL, Seminar Room 258, 2nd floor Chair: Prof. Dr. Hildegard TannerPresentations T-001 to T-004

Talks I:Biomedical EngineeringLocation:DCB, S379, 3rd floor, SouthChair: Prof. Dr. Dominik ObristPresentations T-005 to T-008

Talks I:Biomedical SciencesLocation:DCB, S481, 4th floor, SouthChair: Prof. Dr. Frank StüberPresentations T-009 to T-012

Talks I:Cell BiologyLocation:DCB, EG16, ground floor, NorthChair: Prof. Dr. Mario P. TschanPresentations T-013 to T-016

Talks I:Molecular Biology & BiochemistryLocation:DCB, U113, basementChair: Prof. Dr. Torsten OchsenreiterPresentations T-017 to T-020

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Poster Flash I:Biological SystemsLocation:PYL, Seminar Room 258, 2nd floor

Poster Flash I:Biomedical EngineeringLocation:DCB, S379, 3rd floor, South

Poster Flash I:Biomedical SciencesLocation:DCB, S481, 4th floor, South

Poster Flash I:Cell BiologyLocation:DCB, EG16, ground floor, North

Poster Flash I:Molecular Biology & BiochemistryLocation:DCB, U113, basement

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Talks II:Biological SystemsLocation:PYL, Seminar Room 258, 2nd floor Chair: Prof. Dr. Volker EnzmannPresentations T-021 to T-024

Talks II:Biomedical EngineeringLocation:DCB, S379, 3rd floor, SouthChair: Prof. Dr. Stavroula MougiakakouPresentations T-025 to T-028

Talks II:Biomedical SciencesLocation:DCB, S481, 4th floor, SouthChair: Prof. Dr. Nicola LowPresentations T-029 to T-032

Talks II:Cell BiologyLocation:DCB, EG16, ground floor, NorthChair: Prof. Dr. Thomas KaufmannPresentations T-033 to T-036

Talks II:Molecular Biology & BiochemistryLocation:DCB, U113, basementChair: Prof. Dr. Sebastian LeidelPresentations T-037 to T-040

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Poster Flash II:Biological SystemsLocation:PYL, Seminar Room 258, 2nd floor

Poster Flash II:Biomedical EngineeringLocation:DCB, S379, 3rd floor, South

Poster Flash II:Biomedical SciencesLocation:DCB, S481, 4th floor, South

Poster Flash II:Cell BiologyLocation:DCB, EG16, ground floor, North

Poster Flash II:Molecular Biology & BiochemistryLocation:DCB, U113, basement

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Keynote LectureLocation: DCB, U113, basementProf. Dr. Sylviane Muller, School of Biotechnology, University of Strasbourg, France:«Mechanism-Guided Novel Therapies for Treating Inflammatory Diseases»Chair: PD Dr. Monica Schaller, Coordinator GCB

Closing Remarks, followed by the ApéroLocation: DCB, U113 & Foyer, basementProf. Dr. Frank Stüber, President GCBJoin the Apéro!

IMPORTANT. Due to limited space in the Mensa Bühlplatz, lunch breaks and poster sessions are overlapping. Participants are encouraged to spend part of the breaks for poster viewing in the DCB Foyer.Presenting authors are requested to follw the color codes for their lunch break: Blue = Lunch A for «Blue Groups», Green = Lunch B for «Green Groups». Thank you for your consideration.

GCB Award for Best PhD ThesisLocation: DCB, U113, basementChair: Prof. Dr. Frank Stüber, President GCB

Poster Session ALocation: DCB, Foyer to Room U113 & Cafeteria (basement)Posters: Biological Systems A-001 to A-023; Biomedical Engineering A-024 to A-045; Biomedical Sciences A-046 to A-061;Cell Biology A-062 to A-090; Molecular Biology & Biochemistry A-091 to A-121Poster ExchangeLocation: DCB, Foyer to Room U113 & Cafeteria (basement)Removal of Session A Posters & Display of Session B Posters.

Poster Session BLocation: DCB, Foyer to Room U113 & Cafeteria (basement)Posters: Biological Systems B-122 to A-144; Biomedical Engineering B-145 to A-166; Biomedical Sciences B-167 to A-181;Cell Biology B-182 to A-210; Molecular Biology & Biochemistry B-211 to A-242

Lunch A («Blue Groups») & Poster ViewingLocations: Mensa Bühlplatz (Lunch) & DCB, Foyer & Cafeteria (Posters)Due to limited space, participants are requested to have lunch in 2 groups.Lunch B («Green Groups») & Poster ViewingLocations: Mensa Bühlplatz (Lunch) & DCB, Foyer & Cafeteria (Posters)Due to limited space, participants are requested to have lunch in 2 groups.

Mensa services not available for participants (lunch clearing)

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Coffee Break & Poster Viewing/Poster RemovalLocations: Mensa Bühlplatz (Coffee) & DCB, Foyer & Cafeteria (Poster Viewing/Poster Removal)Removal of Session B Posters: Posters must be removed to allow set-up of the Apéro in the DCB Foyer.

Coffee Break & Poster ViewingLocations: Mensa Bühlplatz (Coffee) & DCB, Foyer & Cafeteria (Posters)

Mensa services not available for participants (lunch preparation)

GCB Symposium 2020 | Program Overview

Check-in of Presenting Authors & Poster DisplayLocation: DCB, Foyer to Room U113, basementDistribution of name tags to presenting authors and chairpersons. Display of Session A Posters.

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O n l i n e A c c e s s | 2

GCB Symposium 2020 | Online Access

As a most comfortable tool for planning and organizing your participation in the GCB Symposium 2020, a direct online access to the GCB Symposium Conference Agenda Session Overview, the full abstract texts, as well as a list of all authors, is provided via the ConfTool Platform. Registration/login authentication is not required.

Link: https://www.conftool.net/gcb-symp/sessions.php/

QR code for your mobile device:

On the GCB Symposium Conference Agenda Session Overview, please select a single session by clicking on the title of the session for a detailed view with full abstract texts. Select a location to show only sessions at that location. Browse the list of authors by selecting «Authors» in the toolbar at the top left, or search for an individual author or presentation title, using the input box in the toolbar at the top right.

Please note that an internet connection/WiFi is required, and that the agenda output is only partly optimized for mobile devices/smartphones. To this effect, click on «Mobile View» at the bottom right on the GCB Symposium Conference Agenda Session Overview.

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GCB Symposium 2020 | Location Map

K e y n o t e L e c t u r e | 4

GCB Symposium 2020 | Keynote Lecture

Mechanism-Guided Novel Therapies for Treating Inflammatory Diseases

Prof. Dr. Sylviane Muller

School of Biotechnology, University of Strasbourg, France

Nowadays, pharmacologic treatments of inflammatory and autoimmune diseases are largely palliative rather than curative. They result in non-specific immunosuppression, which can be associated with disruption of natural and induced immunity with significant, sometimes dramatic, adverse effects. Among the novel strategies that are under development, tools that target specific molecular pathways and cells, and more precisely modulate the immune system to restore normal tolerance mechanisms, are central. In these approaches, peptide therapeutics represent a class of agents that display many physicochemical advantages. Among them, the phosphopeptide P140 is very promising for treating patients with systemic lupus, and probably more largely patients with chronic inflammatory diseases. P140/Lupuzor is currently evaluated in phase III-clinical studies worldwide. This peptide targets key elements of chaperone-mediated autophagy, which are hyperactivated in lupus. The «correcting» effect of P140 on autophagy results in a weaker signaling of autoreactive T and B cells, leading to a significant improvement of physiopathological conditions. These findings open novel avenues of therapeutic intervention in pathological conditions in which reduction of autophagy activity is desired. Promising data have been obtained in animal models mimicking Sjögren’s syndrome and neurological autoimmune diseases. After the era of drugs classified as «disease-modifying» therapeutics, a new type of «mechanism-guided» therapies starts to emerge for treating inflammatory diseases.

P r o g r a m • T a l k s I & P o s t e r F l a s h I | 5

GCB Symposium 2020 | Program: Morning Sessions

08h30–09h45 | Talks I & Poster Flash I

«Biological Systems» | Department of Physiology, Room 258, 2nd floor

Chair: Prof. Dr. Hildegard Tanner, Department for BioMedical Research, University of Bern, and Department of Cardiology, Inselspital, Bern University Hospital

Talks I «Biological Systems» | T-001 to T-004

08h30 Samuel Buntschu, Department of Physiology T-001 Spinal Cord Circuit Reorganization Induced by Stem Cell Transplantation and

Activity-Dependent Plasticity in an in vitro Model of Spinal Cord Injury

08h45 Carolina Herrera, Clinic of Reproductive Medicine, Department for Farm Animals, Vetsuisse Faculty Zurich

T-002 Detection of Exosomes in Blastocoele Fluid of in vitro Produced BovineEmbryos

09h00 Larissa Kernen, Centre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

T-003 Estrogen Regulation of Thymus Development and Function in Zebrafish

09h15 Jasmin Walter, Clinic of Reproductive Medicine, Department for Farm Animals, Vetsuisse Faculty Zurich

T-004 The Equine «Cumulome» Is Highly Influenced by Maturation Condition

Poster Flash I «Biological Systems»

09h30 Presenters and Poster Numbers: A-004 Sidar AydinA-007 Julia BruggisserA-008 Hang BuiA-009 Emanuele BullaA-010 Martina CalióA-014 Melanie Michaela HierwegerA-018 Konstantinos KoukoutselosA-023 Eleonora Lupi

For titles of presentations, see Poster Session A, pp. 17-18.

6 | G C B S y m p o s i u m 2 0 2 0

«Biomedical Engineering» | DCB, Room S379, 3rd floor South

Chair: Prof. Dr. Dominik Obrist, Cardiovascular Engineering (CVE), ARTORG Center for Biomedical Engineering Research, University of Bern

Talks I «Biomedical Engineering» | T-005 to T-008

08h30 Thomas Leonardo Gian-Luca Zanchin, Department of Cardiology, Inselspital, Bern University Hospital

T-005 Predictive Value of the Shear Stress Distribution Estimated in Three Dimensional Quantitative Coronary Angiography Models in Detecting Vulnerable Plaques

08h45 Pauline Zamprogno, Organs-on-Chip Technologies, ARTORG Center for Biomedical Engineering Research

T-006 Second Generation of Lung Alveoli-on-Chip: New Air-Blood Barrier in-vitro Model

09h00 Soheila Zeinali, Organs-on-Chip Technologies, ARTORG Center for Biomedical Engineering Research

T-007 Functional Microvasculature-on-Chip: Vascular Remolding Upon Cyclic Stretch

09h15 Romy Sweda, sitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, and Swiss Cardiovascular Center, Department of Cardiology, Inselspital, Bern University Hospital

T-008 Semi-Invasive Esophageal Mapping System—First in Man Experience

Poster Flash I «Biomedical Engineering»

09h30 Presenters and Poster Numbers: A-025 Fabian Balsiger A-029 Benjamin Eigl A-033 Tom Gawliczek A-035 Jan Hermann A-036 Suyi Hu A-041 Michael Künzler A-042 Thomas Kevin Kurmann A-043 Bastien Le Gars Santoni A-045 Ya Lu

For titles of presentations, see Poster Session A, pp. 18-20.

P r o g r a m • T a l k s I & P o s t e r F l a s h I | 7

«Biomedical Sciences» | DCB, Room S481, 4th floor South

Chair: Prof. Dr. Frank Stüber, Department for BioMedical Research, University of Bern, and Department of Anaesthesiology and Pain Therapy, Inselspital, Bern University Hospital

Talks I «Biomedical Sciences» | T-009 to T-012

08h30 Nanina Anderegg, Institute of Social and Preventive Medicine T-009 Using Multistate Models to Disentangle Mortality and Loss to Follow-Up in

HIV+ Patients

08h45 Sarah Farag, Department of Medical Oncology, Inselspital, Bern University Hospital

T-010 High Incidence of Reversible Renal Toxicity of Dose-Intensified Bendamustine-Based High-Dose Chemotherapy in Lymphoma and Myeloma Patients

09h00 Christina Schindera, Institute of Social and Preventive Medicine, University of Bern, and Division of Pediatric Hematology and Oncology, University Childrenʹs Hospital Basel

T-011 Cardiovascular Risk Factors in Adult Childhood Cancer Survivors—Baseline Results from the SURfit Study

09h15 Katayoun Taghavi, Institute of Social and Preventive Medicine T-012 Cascades to Assess the Cervical Cancer Screening Program in a

Zimbabwean ART Clinic

Poster Flash I «Biomedical Sciences»

09h30 Presenters and Poster Numbers: A-047 Maud Bagnoud A-048 Katrin Melanie Beckmann A-053 Gion Fränkl A-054 Bettina S. Frauchiger A-056 Anthony Hauser A-059 Louise Françoise Martin A-060 Alja Mazzini A-061 Gaia Alessandra Moore-Jones

For titles of presentations, see Poster Session A, pp. 20-21.

8 | G C B S y m p o s i u m 2 0 2 0

«Cell Biology» | DCB, Room EG16, ground floor North

Chair: Prof. Dr. Mario P. Tschan, Division of Experimental Pathology, Institute of Pathology, University of Bern

Talks I «Cell Biology» | T-013 to T-016

08h30 Matteo Rossi Sebastiano, Institute of Pharmacology T-013 ACSL3 Controls Desmoplasia in Pancreatic Cancer

08h45 Pascal Ender, Institute of Cell Biology T-014 ERK Signaling Dynamics Control the Normal and Oncogenic Development of

Breast Epithelial Organoids

09h00 Kim Klapan, Institute of Pharmacology T-015 The Role of the p73-ATG5 Axis in Regulating Autophagy in Atopic Dermatitis

and Psoriasis

09h15 Andrea M. Spiri, Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty Zurich

T-016 An Independent Analysis of Feline Calicivirus Vaccine Immunity

Poster Flash I «Cell Biology»

09h30 Presenters and Poster Numbers: A-065 Güliz Tuba BarutA-066 Johanna BaumgartnerA-068 Hervé BesançonA-069 Verena M. BetzlerA-071 Loïc BorcardA-072 Melanie BrüggerA-075 Elena de MartinA-076 Haibin DengA-079 Martin Erhardt

For titles of presentations, see Poster Session A, pp. 22-24.

P r o g r a m • T a l k s I & P o s t e r F l a s h I | 9

«Molecular Biology & Biochemistry» | DCB, Room U113, basement

Chair: Prof. Dr. Torsten Ochsenreiter, Institute of Cell Biology, University of Bern

Talks I «Molecular Biology & Biochemistry» | T-017 to T-020

08h30 Simona Amodeo, Institute of Cell Biology T-017 Characterization of TAP110, a Protein Associated with the Mitochondrial

Genome Segregation Machinery in Trypanosoma brucei

08h45 Efstathios Katharopoulos, Division of Endocrinology, Diabetology & Metabolism, Department of Pediatrics, Inselspital, Bern University Hospital, and Endocrinology/Diabetology/Metabolism (Paediatrics), Department for BioMedical Research, University of Bern

T-018 In vitro Characterisation of Two Novel Mutations in the STAR Gene Identified in a Girl with Adrenal Insufficiency

09h00 Anca Liliana Cismaru, Department of Clinical Chemistry, Inselspital, Bern University Hospital

T-019 Genetic Case-Control Association Study of Metamizole-Induced Agranulocytosis

09h15 Dominique Brunßen, Institute of Cell Biology T-020 Phenylalanine-tRNA Synthetase Activity in Regulating Feeding and Starvation

Poster Flash I «Molecular Biology & Biochemistry»

09h30 Presenters and Poster Numbers: A-094 Sebastian Toni Bechara A-096 Sara Bonetti A-098 Oliver Caliaro A-099 Lara Contu A-100 Sabina Deutschmann A-104 Ana Belén García-Martín A-107 Nina Gillis-Germitsch A-112 Jan Henkel A-113 Dominic Ritler

For titles of presentations, see Poster Session A, pp. 24-26.

1 0 | G C B S y m p o s i u m 2 0 2 0

09h45–10h15 | Coffee Break (Mensa Bühlplatz) & Poster Viewing

P r o g r a m • T a l k s I I & P o s t e r F l a s h I I | 1 1

10h15–11h30 | Talks II & Poster Flash II

«Biological Systems» | Department of Physiology, Room 258, 2nd floor

Chair: Prof. Dr. Volker Enzmann, Department for BioMedical Research, University of Bern, and Department of Ophthalmology, Inselspital, Bern University Hospital

Talks II «Biological Systems» | T-021 to T-024 10h15 Noëlle Dommann, Visceral and Transplantation Surgery, Department for

BioMedical Research T-021 LIM Protein Ajuba Promotes Cancer Cell Proliferation and Survival in

Colorectal Cancer

10h30 Alexander Ernst, Institute of Anatomy T-022 Actin Dynamics and the Bmp Pathway Drive Apical Extrusion of Proepicardial

Cells

10h45 Yanyun Gao, Thoracic Surgery, Department for BioMedical Research, University of Bern, and Division of General Thoracic Surgery, Inselspital, Bern University Hospital

T-023 Pemetrexed/Cisplatin Therapy Increases Cytidine Deaminase (CDA) and Thymidine Phosphorylase (TYMP) Expression Thereby Inducing Sensitivity to 5'-Deoxy-5-Fluorocytidine (5’-DFCR) in Non-Small-Cell Lung Cancer Cells

11h00 Duo Xu, Department of Thoracic Surgery, Inselspital, Bern University Hospital, and Thoracic Surgery, Department for BioMedical Research, University of Bern

T-024 CRISPR Screening Identifies WEE1 as a Combination Target for Standard Chemotherapy in Malignant Pleural Mesothelioma

Poster Flash II «Biological Systems»

11h15 Presenters and Poster Numbers: B-124 Josep Maria Monné Rodríguez B-125 Arrigo Moro B-135 Raphaela Isabelle Marianne Seeger B-136 Anita Senk B-138 Lotte Johanna Elisabeth Spierenburg B-139 Beatrice Lisa Steiner B-141 Verdiana Trappetti B-143 Emmanouela Volitaki

For titles of presentations, see Poster Session B, pp. 27-28.

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«Biomedical Engineering» | DCB, Room S379, 3rd floor South

Chair: Prof. Dr. Stavroula Mougiakakou, AI in Health and Nutrition, ARTORG Center for Biomedical Engineering Research, University of Bern

Talks II «Biomedical Engineering» | T-025 to T-028

10h15 Alberto Mantegazza, Cardiovascular Engineering (CVE), ARTORG Center for Biomedical Engineering Research

T-025 Microfluidic Investigations of Red Blood Cell Phase Separation in Complex Microchannel Network

10h30 Tatiana Fountoukidou, Artificial Intelligence in Medical Imaging, ARTORG Center for Biomedical Engineering Research

T-026 Concept-Centric Visual Turing Tests for Method Validation

10h45 Daniele Casari, Swiss Federal Laboratories for Materials Science and Technology (Empa), Thun

T-027 Exploring Bone's Basic Building Blocks Microtensile Properties and Toughening Mechanisms on the Lamellar Level

11h00 Laurent Lejeune, Artificial Intelligence in Medical Imaging, ARTORG Center for Biomedical Engineering Research

T-028 A Tracking Approach for Gaze-Based Ground Truth Annotation of Medical Sequences

Poster Flash II «Biomedical Engineering»

11h15 Presenters and Poster Numbers: B-147 Marzieh Ovesy B-149 Iwan Paolucci B-154 Raluca Maria Sandu B-156 Florian Schmaranzer B-157 Daniel Schneider B-160 Yannick Raphael Suter B-161 Maximilien Tholl B-165 Christian Zanchin

For titles of presentations, see Poster Session B, pp. 29-30.

P r o g r a m • T a l k s I I & P o s t e r F l a s h I I | 1 3

«Biomedical Sciences» | DCB, Room S481, 4th floor South

Chair: Prof. Dr. Nicola Low, Institute of Social and Preventive Medicine, University of Bern

Talks II «Biomedical Sciences» | T-029 to T-032

10h15 Annika Bremhorst (Huber), Division of Animal Welfare, VPH Institute, Vetsuisse Faculty Bern, and Animal Behaviour, Cognition and Welfare Group, School of Life Sciences, University of Lincoln, United Kingdom

T-029 Facial Expressions of Positive Anticipation and Frustration in Dogs

10h30 Mattea Sophie Durst, Division of Surgical Research, University Hospital Zurich

T-030 Investigating Pain and Analgesia in the Acute Cerulein-Induced PancreatitisMouse Model

10h45 Matthieu Guichard, Swiss Bee Research Center, Agroscope, Switzerland T-031 Genetic Parameters of Two Swiss Apis mellifera Populations and Their

Implication for Selection

11h00 Shengchen Liu, Department of Intensive Care Medicine, Inselspital, Bern University Hospital

T-032 Effects of ICU Routine Nursing Procedures on Hepatic Hemodynamics in aFecal Peritonitis Porcine Model

Poster Flash II «Biomedical Sciences»

11h15 Presenters and Poster Numbers: B-169 Rebeca MozunB-170 Peter J. NeyerB-171 Maria OtthB-172 Ranya ÖzcelikB-173 Julia K. PrümmerB-177 Andras Laszlo SotiB-178 Meng TianB-179 Nicolas Waespe

For titles of presentations, see Poster Session B, pp. 31-32.

1 4 | G C B S y m p o s i u m 2 0 2 0

«Cell Biology» | DCB, Room EG16, ground floor North

Chair: Prof. Dr. Thomas Kaufmann, Institute of Pharmacology, University of Bern

Talks II «Cell Biology» | T-033 to T-036

10h15 Pascal Näf, Tumor-Immunology, Department for BioMedical Research T-033 IL-33/ST2 Signaling Promotes Hematopoietic Reconstitution After Sub-Lethal

Irradiation

10h30 Pablo Arnold Winzer, Institute of Parasitology, Vetsuisse Faculty Bern T-034 Treatment with Bumped Kinase Inhibitor 1294 Alters Neospora caninum

Protein Expression Which Lead to a Diversified Humoral Immune Response in N. caninum Infected Mice

10h45 Coralie Dessauges, Institute of Cell Biology T-035 A High Throughput Optogenetic System to Interrogate MAPK Signaling

Network Dynamics at the Single Cell Level

11h00 Haitang Yang, Thoracic Surgery, Department for BioMedical Research, University of Bern, and Division of General Thoracic Surgery, Inselspital, Bern University Hospital

T-036 DNA-PKcs as a Potential Targeted Therapy for KRAS-Mutant Cancer

Poster Flash II «Cell Biology»

11h15 Presenters and Poster Numbers: B-184 Mirjam KienerB-187 Nathan LeborgneB-188 Marta LewandowskaB-193 Samara NaimB-194 Nicolas Jan NiklausB-201 Guerric P. B. SamsonB-203 Olivier Pascal SchärenB-207 Tommaso VirgilioA-090 Anna S. Wenning

For titles of presentations, see Poster Sessions B, pp. 32-34, and A, p. 24.

P r o g r a m • T a l k s I I & P o s t e r F l a s h I I | 1 5

«Molecular Biology & Biochemistry» | DCB, Room U113, basement

Chair: Prof. Dr. Sebastian Leidel, Department of Chemistry and Biochemistry, University of Bern

Talks II «Molecular Biology & Biochemistry» | T-037 to T-040

10h15 Michael Brilhante, Institute of Veterinary Bacteriology, Vetsuisse Faculty Bern

T-037 Clinical Contamination with High-Risk Clones of Carbapenemase-Producing Klebsiella pneumoniae Causing Infection in Pets in Switzerland

10h30 Seid Hamzic, Department of Clinical Chemistry, Inselspital, Bern University Hospital

T-038 Evaluating the Role of ENOSF1 and TYMS Variants as Predictors in Fluoropyrimidine-Related Toxicities: An IPD Meta-Analysis

10h45 Nuria Bosch-Guiteras, RNA & Cancer, Department for BioMedical Research, University of Bern, and Department of Medical Oncology, Inselspital, Bern University Hospital

T-039 Improving the Efficiency of Genomic Deletion by CRISPR-Cas9

11h00 Martin Liptay, Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

T-040 Depletion of H2AX Counteracts Replication Fork Degradation and Promotes PARPi Resistance in BRCA-Deficient Mouse Mammary Tumors

Poster Flash II «Molecular Biology & Biochemistry»

11h15 Presenters and Poster Numbers: B-211 Iris Hug B-212 Advaitha Iyer B-213 Aurelio Leandro Jenni B-214 Nicole Patrizia Kadzioch B-216 Alessio Loffreda B-220 Merve Mutlu B-222 Jaime Osuna Luque B-224 Taisia Polidori B-225 Carlos Pulido Quetglas

For titles of presentations, see Poster Session B, pp. 34-36.

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11h30–13h00 & 13h30–15h00 | Poster Sessions

11h30–13h00 | Poster Session A

Posters | A-001 to A-121 DCB, Foyer to Room U113 & Cafeteria, basement

12h30–13h15 | Lunch A (Mensa Bühlplatz) 13h15–14h00 | Lunch B (Mensa Bühlplatz) Presenting authors: Please follow color codes on Program Overview for your lunch time.

13h00–13h30 | Poster exchange Posters of Session A will be removed & Posters of Session B will be displayed.

13h30–15h00 | Poster Session B

Posters | B-122 to B-242 DCB, Foyer to Room U113 & Cafeteria, basement

List of posters: See following pages.

P r o g r a m • P o s t e r S e s s i o n A | 1 7

11h30–13h00 | Poster Session A

Posters | A-001 to A-121 Posters with an asterisk (*) are presented in Poster Flash I and II (see pp. 5-9 and 14).

«Biological Systems» | A-001 to A-023

A-001 Nicoleta Anghel, Institute of Parasitology, Vetsuisse Faculty Bern Ruthenium Complexes for the Treatment of Protozoan Diseases of Medical and

Veterinary Importance A-002 Simon L. April-Monn, Institute of Pathology PanNET Tumoroids: A Novel Promising Preclinical 3D Culture Model for Pancreatic

Neuroendocrine Tumors (PanNETs) A-003 Prakash Arullampalam, Institute of Biochemistry and Molecular Medicine Deletion of Trpm4 Alters the Function and Expression of NaV1.5 Channel in Mouse

Cardiac Myocytes A-004* Sidar Aydin, Theodor Kocher Institute Endothelial Antigen-Presentation Stops the Migration of CD8+T Cells Across the

Blood-Brain Barrier in Neuroinflammation A-005 Stefano Bagatella, Division of Experimental Clinical Research, Department of

Clinical Research and Veterinary Public Health (DCR-VPH), Vetsuisse Faculty Bern Bovine Neutrophil Chemotaxis to and Interaction with Listeria monocytogenes A-006 Ida Boccalaro, Center for Experimental Neurology, Department of Neurology,

Inselspital, Bern University Hospital, and Neurology, Department for BioMedical Research, University of Bern

Modulation of Brain Circuits for Sensory Processing During Sleep States A-007* Julia Bruggisser, Institute of Animal Pathology, Department of Infectious Diseases

and Pathobiology, Vetsuisse Faculty Bern Cell-Specific Targeting by Clostridium perfringens β-Toxin Unraveled: The Role of

CD31 as the Toxin Receptor A-008* Hang Bui, Institute of Pathology Cell Type-Specific Regulation of Interleukin-1-Driven Inflammation A-009* Emanuele Bulla, Ophthalmology, Department for BioMedical Research Nuclear Receptor Corepressors in Murine Photoreceptor Development A-010* Martina Calió, Institute of Medical Engineering, Lucerne University of Applied

Sciences and Arts, Horw, and Tissue Engineering for Orthopaedics & Mechanobiology, Department for BioMedical Research, University of Bern

Mechanical Unloading and in vitro Culture of Articular Chondrocytes A-011 Carlo Cerquetella, Department of Physiology Neural Circuits for Emotional Conflicts and Decision Making in the Ventral CA1

Hippocampus A-012 Gabriele Chiffi, Institute for Infectious Diseases Sleep-Wake Disturbances Following Tick-Borne Encephalitis (TBE) A-013 Federica Angela Franciosa, Department of Physiology Peripheral Inflammation Causes Hyperexcitability of the L5 Pyramidal Neurons in the

Anterior Cingulate Cortex upon Continuos Noxious Stimulation

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A-014* Melanie Michaela Hierweger, NeuroCenter, Division of Neurological Sciences, Vetsuisse Faculty Bern

Parainfluenza Virus 5 Infection in Neurological Disease and Encephalitis of Cattle A-015 Daniela Ivan, Theodor Kocher Institute Mechanisms of Myeloid Cell Invasion and Polarization in Autoimmune CNS

Inflammation A-016 Andrea Karolin, Nephrology and Hypertension, Department for BioMedical Research A Single Nucleotide Polymorphism of TWEAK Predicts Arterio- and

Arteriolohyalinosis in Kidney Transplants and Is Associated with Allograft Survival A-017 Alicia Michelle Kemble, Theodor Kocher Institute, University of Bern, and

Neuroscience, Research & Development, F. Hoffman La-Roche Ltd, Basel Efficacy of Angpt2 Inhibition in EAE (Experimental Autoimmune Encephalomyelitis)

Mouse Models of Multiple Sclerosis A-018* Konstantinos Koukoutselos, Department of Physiology Neural Correlates for Anxiety and Its Prediction in the Ventral CA1 Hippocampus A-019 Jakub Králik, Department of Physiology Opto-mGluR6 Optogenetic Toolbox: Functional Comparison of ON-Bipolar Cell

Targeted Gene Therapy in Murine Blind Retinas Using Multi-Electrode Arrays A-020 Philipp Andreas Kronenberg, Institute of Parasitology, Vetsuisse and Medical

Faculty, University of Zurich Early Serological Diagnosis of Human Alveolar Echinococcosis A-021 Patrycja Kucharczyk, Department of Nephrology and Hypertension, Inselspital, Bern

University Hospital, and Nephrology and Hypertension, Department for BioMedical Research, University of Bern

Carbonic Anhydrase Is a Molecular Target of Thiazide-Induced Glucose Intolerance A-022 Michelle A. Küffer, Urology, Department for BioMedical Research Up-Regulation of the Inflammatory Gene Expression in Mouse Models of Obstructive

and Neurogenic Bladder Dysfunction A-023* Eleonora Lupi, Institute of Anatomy, University of Bern, and ACQUIFER, a Division

of DITABIS, Digital Biomedical Imaging Systems AG, Pforzheim, Germany High Content Screening Assay for the Identification of Compounds Enhancing

Epicardium Formation

«Biomedical Engineering» | A-024 to A-045

A-024 Philipp Aebischer, Hearing Research Laboratory, ARTORG Center for Biomedical Engineering Research, and Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital

Analysis of Insertion Angles of Lateral Wall Cochlear Implant Electrode Arrays in Computed Tomography Images

A-025* Fabian Balsiger, Insel Data Science Center, Inselspital, Bern University Hospital; NMR Laboratory, Institute of Myology, Neuromuscular Investigation Center, France; NMR Laboratory, CEA, DRF, IBFJ, MIRCen, France

Quantification of Fat Fraction and Water T1 in Neuromuscular Diseases Using Deep Learning-Based Magnetic Resonance Fingerprinting

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A-026 Angela Amira Botros, Gerontechnology and Rehabilitation, ARTORG Center for Biomedical Engineering Research

At-Home Motor Symptom Monitoring of Parkinson’s Disease Patients—Results from a Pilot Study

A-027 Dominik Brügger, Department of Ophthalmology, Inselspital, Bern University Hospital

Low Latency EEG Phase Estimation for Real-Time EEG Phase-Locked Stimulus Presentation in Humans

A-028 Martyna Dziadosz, Magnetic Resonance Spectroscopy and Methodology (AMSM), Department for BioMedical Research, University of Bern, and Department of Radiology, Inselspital, Bern University Hospital

A Novel Non-Water-Excitation Magnetic Resonance Spectroscopy Sequence to Detect Metabolites with Exchangeable Protons in the Human Brain at 3T

A-029* Benjamin Eigl, Chair for Image-Guided Therapy, ARTORG Center for Biomedical Engineering Research, University of Bern, and CAScination AG, Bern

Registration Techniques for Computer-Aided Endopancreatic Surgery A-030 Dario Ferrari, Organs-on-Chip Technologies Laboratory, ARTORG Center for

Biomedical Engineering Research Development of a Fibrosis-on-Chip Tool for Drug Efficacy Testing A-031 Tim Fischer, Department of Otorhinolaryngology, Head and Neck Surgery,

Inselspital, Bern University Hospital, and Hearing Research Laboratory, ARTORG Center for Biomedical Engineering Research, University of Bern

Spatial Hearing Benefits with a Temporal Fine Structure Preserved Coding Strategy Are Not Transferable to Realistic Listening Scenarios

A-032 Nicolas Franzina, sitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, and Department of Cardiology, Inselspital, Bern University Hospital

A Miniaturized Endocardial Electromagnetic Energy Harvester for Leadless Cardiac Pacemakers

A-033* Tom Gawliczek, Hearing Research Laboratory, ARTORG Center for Biomedical Engineering Research, University of Bern, and Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital

Influence of Maximum Power Output on Speech Understanding with Bone Conduction Hearing Devices

A-034 Camille Gontier, Department of Physiology Identifiability and Optimal Experiment Design for Synaptic Transmission A-035* Jan Hermann, Chair for Image-Guided Therapy, ARTORG Center for Biomedical

Engineering Research Towards Robotic Embedding of Cochlear Implants in the Temporal Bone A-036* Suyi Hu, Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital,

Bern University Hospital, and Hearing Research Laboratory, ARTORG Center for Biomedical Engineering Research, University of Bern

Characteristics and Reproducibility of Residual Inhibition After Repeated Acoustic Stimulation

A-037 Michael Indermaur, Musculoskeletal Biomechanics, ARTORG Center for Biomedical Engineering Research

Compressive Strength of Bone ECM in Fixed Iliac Crest Biopsies from OI Patients Increases with Degree of Mineralization

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A-038 Alain Jungo, Insel Data Science Center, Inselspital, Bern University Hospital, andARTORG Center for Biomedical Engineering Research, University of Bern Assessing Reliability and Challenges of Uncertainty Estimations for Medical Image Segmentation

A-039 Sergej Kasavica, Department of PhysiologyLong Range Cortical Circuits in Sensory Association and Perception

A-040 Tatiana Kochetkova, Laboratory for Mechanics of Materials & Nanostructures, SwissFederal Laboratories for Materials Science and Technology (Empa), Thun Polarized Raman Spectroscopy as a Method for Quantitative Analysis of Bone Fibril Orientation

A-041* Michael Künzler, Department of Orthopaedic Surgery and Traumatology, Inselspital,Bern University Hospital; VA Long Beach Healthcare System, Long Beach, CA, USA; Musculoskeletal Research Unit (MSRU), Department of Molecular Mechanisms of Disease, Vetsuisse Faculty Zurich The Effect of PARP-1 Inhibition on Rotator Cuff Healing—A Feasibility Study Using Veliparib in a Rat Model of Acute Rotator Cuff Repair

A-042* Thomas Kevin Kurmann, Artificial Intelligence in Medical Imaging, ARTORG Centerfor Biomedical Engineering Research Expert-Level Automated Biomarker Identification in Optical Coherence Tomography Scans

A-043* Bastien Le Gars Santoni, Bone Biology and Orthopaedic Research, Department forBioMedical Research, University of Bern, and Bioceramics and Biocompatibility Group, RMS Foundation, Bettlach Effect of the Ca/P Molar Ratio on the Osteoclastic Resorption of Pure Beta-TCP Cylinders

A-044 Deming Liang, sitem Center for Translational Medicine and BiomedicalEntrepreneurship, and Translational Electrophysiology, Cardiovascular Engineering, ARTORG Center for Biomedical Engineering Research Combining Deep Learning Method with Optical Coherence Tomography for Ablation Lesion Assessment

A-045* Ya Lu, AI in Health and Nutrition, ARTORG Center for Biomedical EngineeringResearch AI for Dietary Assessment: goFOOD

«Biomedical Sciences» | A-046 to A-061

A-046 Serra Lem Asangbeh, Institute of Social and Preventive MedicineIndicators and Targets for Cervical Cancer Prevention Programmes in Countries with the Highest HIV Burden: A Policy Review

A-047* Maud Bagnoud, Department of Neurology, Inselspital, Bern University HospitalMechanisms to Improve Glucocorticosteroid Efficacy in Multiple Sclerosis

A-048* Katrin Melanie Beckmann, Clinic for Small Animal Surgery, Department for SmallAnimals, Vetsuisse Faculty Zurich Putative Resting State of the Canine Brain

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A-049 Johanna Karin Bernhard, Clinic for Ruminants, Department of Clinical VeterinaryMedicine, Vetsuisse Faculty Bern Lame Cows in Tie Stalls Behave Differently Than Their Non-Lame Controls

A-050 Marius Reto Bigler, Department of Cardiology, Inselspital, Bern University HospitalFunctional Assessment of Myocardial Ischemia by Intracoronary Electrocardiogram

A-051 Eric Buffle, Department of Cardiology, Inselspital, Bern University HospitalAddition of Passive Leg Raise to Low-Dose Dobutamine Stress Echocardiography in the Diagnosis of Low-Flow, Low-Gradient Aortic Stenosis

A-052 Tafadzwa Gladys Dhokotera, Institute of Social and Preventive Medicine, Universityof Bern, and National Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa Cervical Cancer Risk in Women Living with HIV, Results from the South African HIV Cancer Match Study

A-053* Gion Fränkl, SCI Population Biobanking & Translational Medicine, Swiss ParaplegicResearch, Nottwil Psychological Distress and Accelerated Aging in SCI Patients—A Longitudinal Pilot Feasibility Study

A-054* Bettina S. Frauchiger, Pediatric Respiratory Medicine, Department of Pediatrics,Inselspital, Bern University Hospital Longitudinal Tracking Ability of LCI in Children with Cystic Fibrosis

A-055 Manuela Gerber, Clinic for Ruminants, Department of Clinical Veterinary Medicine,Vetsuisse Faculty Bern Decision-Making Process of Farmers Regarding Antimicrobial Reduction and the Role of the Veterinarian in This Process

A-056* Anthony Hauser, Institute of Social and Preventive MedicineThe Impact of Scaling up Dolutegravir on Antiretroviral Resistance in South Africa

A-057 Jasmine Léa Jendoubi, Department of Neurology, Inselspital, Bern UniversityHospital A Multi-Disciplinary Approach to the Assessment of the Impact of Stroke Characteristics on Sleep and Selected Cognitive Functions

A-058 Sarah Kaiser-Thom, Swiss Institute of Equine Medicine (ISME), Department ofClinical Veterinary Medicine, Vetsuisse Faculty Bern, University of Bern, and Agroscope, Switzerland Investigation of the Bacterial Skin Microbiome and Resistance Patterns of Staphylococcal Species in Equine Pastern Dermatitis Affected Horses

A-059* Louise Françoise Martin, Clinic for Zoo Animals, Exotic Pets and Wildlife, VetsuisseFaculty Zurich Short Term Feeding Preferences in Rabbits Exposed to Diets Varying in Grit Content

A-060* Alja Mazzini, Division of Animal Welfare, VPH Institute, Vetsuisse Faculty BernDevelopment of «The Big Play and Motivation Questionnaire for Dogs»

A-061* Gaia Alessandra Moore-Jones, Centre for Fish and Wildlife Health, Department ofInfectious Diseases and Pathobiology, Vetsuisse Faculty Bern Epidemiological Study of Dichelobacter nodosus in Free Ranging Alpine Ibex (Capra ibex ibex) and Other Potential Hosts: Identifying Maintenance Hosts and Risk Factors of Infection

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«Cell Biology» | A-062 to A-090

A-062 Christina Andronikou, Institute of Animal Pathology, Department of InfectiousDiseases and Pathobiology, Vetsuisse Faculty Bern Targeting PARG Loss-Mediated PARP Inhibitor Resistance in BRCA2-Deficient Tumors

A-063 Marc Artinger, Biotechnology Institute Thurgau (BITg), at the University of Konstanz,Kreuzlingen The CCR7 Glycocalyx Shape in Controlling Receptor Function and Ligand Recognition

A-064 Chantal Lea Bachmann, Tumor-Immunology, Department for BioMedical ResearchImmune-Checkpoints in the Regulation of Leukemia and Cancer Stem Cells

A-065* Güliz Tuba Barut, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern,and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern Response of Bovine Peripheral Blood Dendritic Cells (DCs) and Monocytes to Toll-Like Receptor (TLR) Stimulation

A-066* Johanna Baumgartner, Institute of PathologyImpact of Oxidized Phospholipid/Nrf2 Signaling on Macrophage Differentiation and Functionality in Health and Disease

A-067 Cecilia Bazzini, Dermatology, Department for BioMedical Research, University ofBern, and Department of Dermatology, Inselspital, Bern University Hospital Simple and Sensitive Assays to Detect Autoantibodies Against Alpha 2 Macroglobulin-Like 1 in Paraneoplastic Pemphigus Sera

A-068* Hervé Besançon, Institute of AnatomyTailored Liposomal Nanotraps for the Treatment of Streptococcal Infections

A-069* Verena M. Betzler, Biotechnology Institute Thurgau (BITg) at the University ofKonstanz, Kreuzlingen Investigating Forces at the Immunological Synapse

A-070 Annina Bindschedler, Institute of Cell BiologyHost Cell Nrf2 Signaling in Plasmodium berghei-Infected Liver Cells

A-071* Loïc Borcard, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern,and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern Assessing the Importance of Influenza A Virus Neuraminidase in Viral Propagation

A-072* Melanie Brügger, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern,and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern Respiratory Syncytial Virus Is Altering the Properties of Lung Mesenchymal Stem/Stromal Cells

A-073 Francis Brühlmann, Institute of Animal Pathology, Department of InfectiousDiseases and Pathobiology, Vetsuisse Faculty Bern Targeting Theileria Effector Proteins at the Schizont Membrane

A-074 Xinyue Chang, Division of Immunology, Department of Rheumatology, Immunologyand Allergology (RIA), Inselspital, Bern University Hospital Low-Affinity but High-Avidity Interactions Explain Allergen Cross-Reactivity

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A-075* Elena de Martin, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern, and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

When Viruses and the Innate Immune System Meet: Comparison of Different Pestiviral Erns in Evasion of Innate Immunity

A-076* Haibin Deng, Department of Thoracic Surgery, Inselspital, Bern University Hospital, and Thoracic Surgery, Department for BioMedical Research, University of Bern

Lung Cancer Tumor Initiation Capacity Is Dependent on Lactate Metabolism A-077 Carmen Disler, Institute of Animal Pathology, Department of Infectious Diseases and

Pathobiology, Vetsuisse Faculty Bern Complementary in vivo and in vitro Approaches Identify LRRC8A, LRRC8D and

NAA60 as Major Determinants of Platinum Drug Sensitivity A-078 Dzhangar Dzhumashev, Department of Pediatric Hematology and Oncology,

Inselspital, Bern University Hospital, and Hematology/Oncology, Department for BioMedical Research, University of Bern

Screening of Peptide Ligands for Targeted Drug Delivery to Rhabdomyosarcoma Cells

A-079* Martin Erhardt, Institute of Pharmacology Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to

Migration and Invasion by Activation of PI3-Kinase and Akt A-080 Pascal Gasser, Immunology Research, Rheumatology, Department for BioMedical

Research, University of Bern, and Division of Immunology, Department of Rheumatology, Immunology and Allergology (RIA), Inselspital, Bern University Hospital

Molecular, Structural and Mechanistic Insight into Ligelizumab Mediated Suppression of IgE Dependent Allergic Responses

A-081 Eleftheria Girousi, Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern

The Role of IRF6, GRHL3 and KLF4 in Cleft Lip and Palate, Wound Healing and Cancer

A-082 Martín González Fernández, Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

Chemogenetic Interactions to Elucidate Response Mechanisms to Taxane Anti-Cancer Therapy

A-083 Vaiva Gradauskaite, Division of Experimental Clinical Research, DCR-VPH, Vetsuisse Faculty Bern

Towards NextGen Precision Cancer Immunotherapy A-084 Mitra Gultom, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern;

Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern; Institute for Infectious Diseases

Establishment of Camelid Airway Cultures for the Molecular Characterization of Middle East Respiratory Syndrome Coronavirus

A-085 Silvan Rolf Heeb, Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, and Hematology, Department for BioMedical Research, University of Bern

Anti-ADAMTS13 Autoantibody-Specific Anti-Idiotypic Antibodies Restore ADAMTS13 Activity in Immune-Mediated Thrombotic Thrombocytopenic Purpura (iTTP) Patients

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A-086 Melle Holwerda, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern;Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern; Institute for Infectious Diseases Establishment of a Reverse Genetic System for the Cattle Associated Influenza D Virus

A-087 Marc-Antoine Jacques, Institute of Cell BiologyUnraveling Complex Biological Dynamics with Interpretable Convolutional Neural Networks

A-088 Cristina Kalbermatter, Gastroenterology/Mucosal Immunology, Department forBioMedical Research The Role of Maternal Microbiota in Durably Shaping Intestinal Immunity and Gene Expression in the Offspring Through Epigenetic Mechanisms

A-089 Mirela Kremenovic, Institute of PathologyInvestigating the Role of Dendritic Cell Subsets in Regulating the Immune Response to Cancer Immunotherapy

A-090* Anna S. Wenning, Gastroenterology/Mucosal Immunology, Department forBioMedical Research Neonatal Skin Barrier Is Shaped by Embryonic Exposure to Maternal Microbiota

«Molecular Biology & Biochemistry» | A-091 to A-121

A-091 Salome Aeschlimann, Department of Chemistry and BiochemistryFunctional Analysis of the TAC Complex in Trypanosoma brucei

A-092 Joyce Odeke Akello, Institute for Infectious Diseases, University of Bern, and SpiezLaboratory, Federal Office for Civil Protection (FOCP), Spiez Development of a Sample Preparation Pipeline for Identification of Emerging Viral Pathogens from Vectors: An Efficient and Reproducible Method for Vector-Enabled NGS Analysis

A-093 Mengjing Bao, Institute of Cell BiologyFunction of Glutamylation of α-Tubulin in Regulating Protein/RNA Transport in Drosophila Ovary

A-094* Sebastian Toni Bechara, Institute of Cell BiologyInvestigating the Nowa Protein Family and lncRNAs in Paramecium tetraurelia

A-095 Shubha Bevkal Subramanyaswamy, Institute of Cell BiologyStage-Specific Function of Alba3 in Trypanosoma brucei

A-096* Sara Bonetti, Institute of Biochemistry and Molecular Medicine, and Swiss NationalCentre of Competence in Research (NCCR) TransCure First Structure of an MCT1 (SLC16A1) and MCT4 (SLC16A3) L-Lactate Transporter Homologue: Insights into Substrate Binding and Transport

A-097 Rebecca Brogli, Department of Chemistry and BiochemistryA tRNA Half Modulates Translation as Stress Response in Trypanosoma brucei

A-098* Oliver Caliaro, Department of Chemistry and BiochemistryIntracellular Trafficking and Uncoating of Human Parvovirus B19

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A-099* Lara Contu, Department of Chemistry and Biochemistry Investigating the Relationship Between Semliki Forest Virus (SFV) Infection and the

NMD Pathway A-100* Sabina Deutschmann, Department of Chemistry and Biochemistry Importance of Lateral Enzyme Distance on Proton Coupling of Terminal Respiratory

Oxidase and ATP Synthase A-101 Luca Dick, Institute of Biochemistry and Molecular Medicine Development of Positron-Emission Tomography and Fluorescent Tracers for the

Imaging of Calcium Sensing Receptors (CaSR) in Parathyroid Glands A-102 Nicolas Dolder, Department of Chemistry and Biochemistry A Novel Probe Consisting of a pH-Sensitive Dye Coupled to Lipophilic DNA to

Measure Membrane Protein Function in Unilamellar Vesicles A-103 Michel Fasnacht, Department of Chemistry and Biochemistry Function of 5-OH-C2501 in the Peptidyl Transferase Centre A-104* Ana Belén García-Martín, Institute of Veterinary Bacteriology, Vetsuisse Faculty

Bern Whole-Genome Sequence of the Predominant Brachyspira hyodysenteriae in Pigs in

Switzerland A-105 Matthieu Marc Gast, Division of Neurological Sciences, DCR-VPH, Vetsuisse

Faculty Bern Does Oligomerization of Canine Distemper Virus (CDV) Matrix Protein Control

Membrane Budding Activity? A-106 Tim Johan Gelmi, Forensic Toxicology and Chemistry, Institute of Forensic Medicine Cannabinoid Concentrations in Confiscated Cannabis Samples and in Whole Blood

and Urine After Smoking CBD-Rich Cannabis as a «Tobacco Substitute»

A-107* Nina Gillis-Germitsch, Institute of Parasitology, Vetsuisse Faculty Zurich Characterization of Angiostrongylus vasorum Proteins and Their Role in Host Blood

Coagulation Using Rotational Thromboelastometry A-108 Sandra Glasmacher, Institute of Biochemistry and Molecular Medicine Biochemical and Analytical Characterization of Peptide Endocannabinoids A-109 Carole Salome Grädel, Institute for Infectious Diseases Application of Nanopore Sequencing to Genotyping of Human Enterovirus Cases in

Bern A-110 Irene Monika Häfliger, Institute of Genetics, Vetsuisse Faculty Bern Exploiting Massive Genome-Wide Genotyping and Sequencing Data to Improve

Fertility and Rearing Success in the Local Brown Swiss Cattle Population A-111 Alexander Christoph Haindrich, Institute of Plant Sciences Characterization of Proline Transporters in Trypanosoma brucei A-112* Jan Henkel, Institute of Genetics, Vetsuisse Faculty Bern, and DermFocus,

University of Bern Selection Signatures in Goats Reveal Copy Number Variants Underlying Breed-

Defining Coat Color Phenotypes A-113* Dominic Ritler, Institute of Parasitology, Vetsuisse Faculty Bern Identification of Novel Drug Targets in Echinococcus multilocularis by Metabolomics

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A-114 Damian Hertig, Departments for BioMedical Research and Radiology, University ofBern, and Department of Clinical Chemistry, Inselspital, Bern University Hospital Life Monitoring of Cellular Metabolism and Mitochondrial Respiration in 3D Cell Culture System Using NMR Spectroscopy

A-115 Virginia Laura Hill, Institute of Veterinary Bacteriology, Vetsuisse Faculty BernIdentification and Characterization of Different Toxin-Antitoxin (TA) Systems in Mycoplasma mycoides subsp. capri

A-116 Yoandry Hinojosa, Institute of Virology and Immunology (IVI), Vetsuisse FacultyBern, University of Bern; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern, University of Bern; Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba Identification of Virulence Factors of Classical Swine Fever Virus Using a Pair of Evolutionary Related High and Low Virulent Isolates

A-117 Bolaji Nafisat Isiaka, Institute of Cell BiologyTranscription Dynamics at the Single Molecule Level in Individual Promoters

A-118 Lyna Kabbani, Institute of Cell BiologyDNA:RNA Hybrids and Their Role During Genomic Rearrangements in Paramecium tetraurelia

A-119 Satish Kantipudi, Institute of Biochemistry and Molecular MedicineFunction of the Human Heteromeric Amino Acid Transporter 4F2hc-LAT2

A-120 Elham Kashani, Institute of PathologyPP2A-Regulated Temozolomide (TMZ) Resistance in Glioblastoma

A-121 Annika Kratzel, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern,and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern Susceptibility of Human and Camelid Airway Epithelium to Coronaviruses

Note: Please remove posters of Session A and display posters of Session B during the Lunch Break, between 13h00 and 13h30.

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13h30–15h00 | Poster Session B

Posters | B-122 to B-242 Posters with an asterisk (*) are presented in Poster Flash II (see pp. 11-15).

«Biological Systems» | B-122 to B-144

B-122 Josephine Angelo Mapunda, Theodor Kocher Institute Imaging the Central Nervous System Immune Privilege: The Role of Brain Barriers in

Regulating Trafficking of Immune Cells and Immune Mediators in the Central Nervous System

B-123 Joana Mendes Duarte, Department of Physiology Untangling Ventral Hippocampus Dynamics During Contextual Emotional Memory B-124* Josep Maria Monné Rodríguez, Institute of Veterinary Pathology, Vetsuisse Faculty

Zurich Remodelling in Feline HCM B-125* Arrigo Moro, Institute of Bee Health, DCR-VPH, Vetsuisse Faculty Bern Keep Your Enemy Even Closer: Local Adaptation of Naturally Surviving Bees to Their

Sympatric Mites B-126 Mohana Mukherjee, Institute for Infectious Diseases Direct and Microbiota Mediated Effects of Arsenic on the Mammalian Host B-127 Matheus Notter Dias, Institute for Infectious Diseases Effect of Benzoxazinoid Metabolites on the Gut Microbiota and Host Health B-128 Carla Pernaci, Center for Experimental Neurology, Department of Neurology,

Inselspital, Bern University Hospital, and Neurology, Department for BioMedical Research, University of Bern

Investigating the Role of Cerebellar Circuitry in Spinocerebellar Ataxia-1 (SCA1) Pathology

B-129 Federica Pilotto, Neurology, Department for BioMedical Research, University of Bern, and Center for Experimental Neurology, Department of Neurology, Inselspital, Bern University Hospital

Maintaining ER- Mitochondria Contacts Is Neuroprotective in Preclinical Models of ALS

B-130 William Robert Pownall, Division of Surgery, Small Animal Clinic, Department of Clinical Veterinary Science, Vetsuisse Faculty Bern, and Department of Clinical Research and Veterinary Public Health, Vetsuisse Faculty Bern

Generation of a Listeria monocytogenes Vaccine Vector Platform for Canine Brain Cancer Therapy

B-131 Constanze Raltschev, Department of Physiology Sensory Association and Mismatch in the Posterior Parietal Cortex B-132 Patricia Renz, Prenatal Medicine, Department for BioMedical Research, University of

Bern, and Department of Obstetrics and Feto-Maternal Medicine, Inselspital, Bern University Hospital

Astrocyte Polarization in Perinatal White Matter Injury and Its Contribution to Disease Outcomes

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B-133 Maria Saliakoura, Institute of Pharmacology ACSL3 Mediates the KRAS-Dependent Prostaglandin Production and Tumorigenesis

in Non-Small Cell Lung Cancer B-134 Raquel Adaia Sandoval Ortega, Department of Physiology, and Interfaculty

Research Cooperation, «Decoding Sleep: From Neurons to Health & Mind», University of Bern

Thalamic Gating of Painful Stimuli During Sleep and Wake B-135* Raphaela Isabelle Marianne Seeger, Institute of Anatomy Time-Resolved Synaptic Cytomatrix and Exocytosis Architecture B-136* Anita Senk, Institute of Anatomy «Vascular Mimicry»-Like Mechanism of Angiogenesis During the Zebrafish Fin

Regeneration B-137 Patcharamon Seubnooch, Hepatology, Department for BioMedical Research Mass Spectrometry Imaging: The Molecular Diagnostic Tool for Non-Alcoholic Fatty

Liver Disease B-138* Lotte Johanna Elisabeth Spierenburg, Department of Physiology Plasticity Mechanisms in Layer 5 Pyramidal Neurons of the Anterior Cingulate Cortex B-139* Beatrice Lisa Steiner, Department of Ophthalmology, Inselspital, Bern University

Hospital, and Ophthalmology, Department for BioMedical Research, University of Bern

Molecular Mechanisms of NR2E3-Linked Hereditary Retinal Degenerations B-140 Leticia Tavares Gomes, Division of Experimental Clinical Research, Division of

Neurological Diseases, DCR-VPH, Vetsuisse Faculty Bern Dissecting the Infection Cycle of Listeria monocytogenes in Microglia B-141* Verdiana Trappetti, Institute of Anatomy Synchrotron Microbeam Radiotherapy Induces Robust Immunomodulatory Response

in a Mouse Model of Melanoma B-142 Luca Gabriele Valente, Institute for Infectious Diseases, University of Bern, and

Department of Intensive Care Medicine, Inselspital, Bern University Hospital Isolation and Characterization of Novel Staphylococcus epidermidis Bacteriophages

with Therapeutic Potential B-143* Emmanouela Volitaki, Department of Physiology Neural Circuit Dynamics in the Ventral CA1 Hippocampus During Anxiety B-144 Vivian Pham Vu, Institute of Pathology The Role of IL-33 for MPN Progression

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«Biomedical Engineering» | B-145 to B-166

B-145 Anjani K. Maurya, Center for X-ray Analytics, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen, and Laboratory for Biomimetic Membranes and Textiles, Swiss Federal Laboratories for Materials Science and Technology (Empa), St. Gallen

Nucleation and Growth Study of Iron Oxide Nanoparticles from Solution for Biomedical Application

B-146 Fabian Mueller, Chair for Image-Guided Therapy, ARTORG Center for Biomedical Engineering Research

Refined Process Model for Robotic Inner Ear Access B-147* Marzieh Ovesy, Musculoskeletal Biomechanics, ARTORG Center for Biomedical

Engineering Research Nonlinear Explicit µFE Simulation of Dental Implant Insertion in Trabecular Bone B-148 Özhan Özen, Motor Learning and Neurorehabilitation, ARTORG Center for

Biomedical Engineering Research It Is Your Move: Robotic Assistance That Promotes Trainee's Movement Exploration B-149* Iwan Paolucci, Chair for Image-Guided Therapy, ARTORG Center for Biomedical

Engineering Research Ex-vivo Evaluation of an Ultrasound-Based Planning and Navigation Method for Non-

Anatomical Liver Resections B-150 Joaquin Penalver-Andres, Motor Learning and Neurorehabilitation, ARTORG

Center for Biomedical Engineering Research Monitoring Cognitive Status During Motor Learning: Effects of Explicitness of Task

Instruction on Recruited Brain Networks and Motor Performance B-151 Leonardo Pietrasanta, Cardiovascular Engineering, ARTORG Center for Biomedical

Engineering Research Flow Patterns in the Aortic Root: A Comparative in-vitro Study Between a

Bioprosthetic Valve, Bi-Leaflet Mechanical Valve and a Tri-Leaflet Mechanical Valve B-152 Michael Rebsamen, Support Center for Advanced Neuroimaging (SCAN),

Department of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital

Outcome-Based Evaluation of Brain Morphometry Methods B-153 Christoffer Roepstorff, Equine Sports Medicine Unit, Equine Department, Vetsuisse

Faculty Zurich An Approach to Reliable and Clinically Applicable Step Detection in Trotting and

Walking Horses B-154* Raluca Maria Sandu, Chair for Image-Guided Therapy, ARTORG Center for

Biomedical Engineering Research Quantitative Assessment of Liver Microwave Ablation Outcomes in Patients with

Colorectal Liver Metastases B-155 Denis Schenk, Musculoskeletal Biomechanics, ARTORG Center for Biomedical

Engineering Research Clinical Reproducibility of Homogenized Finite Element Bone Strength Estimated

Based on Multiple Section HR-pQCT Reconstructions

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B-156* Florian Schmaranzer, Department of Orthopaedic Surgery and Traumatology, Inselspital, Bern University Hospital

Automatic MRI-Based 3D Models of Hip Cartilage Using a 3D U-Net-Like Fully Convolutional Network for Improved Morphologic and Biochemical Analysis

B-157* Daniel Schneider, Chair for Image-Guided Therapy, ARTORG Center for Biomedical Engineering Research

Life-Like Rendering of Inner Ear Anatomy B-158 Narayan Schütz, Gerontechnology and Rehabilitation, ARTORG Center for

Biomedical Engineering Research Identification and Validation of Digital Biomarkers in Community-Dwelling Older

Adults: Can We Gain Health Relevant Insights Out of Sensorized Home Care Systems?

B-159 Kadir Şimşek, Magnetic Resonance Spectroscopy and Methodology (AMSM), Department for BioMedical Research, University of Bern, and Department of Radiology, Inselspital, Bern University Hospital

Diffusion-Weighted MR Spectroscopy at Short TE with Ultrastrong Gradients to Investigate the Human Brain Microstructure and Macromolecular Signals

B-160* Yannick Raphael Suter, Insel Data Science Center, Inselspital, Bern University Hospital, and ARTORG Center for Biomedical Engineering Research, University of Bern

Radiomics for Glioblastoma Survival Analysis in Pre-Operative MRI: Exploring Feature Robustness, Class Boundaries, and Machine Learning Techniques

B-161* Maximilien Tholl, sitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, and Department of Cardiology, Inselspital, Bern University Hospital

Subdermal Solar Energy Harvesting for Electronic Implants B-162 Maria F. Vasiloglou, AI in Health and Nutrition, ARTORG Center for Biomedical

Engineering Research Nutrition and Diet Apps: A Preliminary Analysis of a Survey Between Medical Doctors

and Nurses B-163 Benjamin Voumard, Musculoskeletal Biomechanics, ARTORG Center for Biomedical

Engineering Research Automated Computation of a Femoral Anatomical Coordinate System Based on

Proximal Landmarks B-164 Siqing Yu, Department of Ophthalmology, Inselspital, Bern University Hospital Neuroprotective Efficacy and Safety of Rasagiline in Patients with Macula-Off Retinal

Detachment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial B-165* Christian Zanchin, Department of Cardiology, Inselspital, Bern University Hospital Acute Coronary Syndrome in Young Patients: Prevalence, Mechanisms and Clinical

Outcomes Following Percutaneous Coronary Intervention B-166 Guodong Zeng, ARTORG Center for Biomedical Engineering Research, and sitem

Center for Translational Medicine and Biomedical Entrepreneurship Hybrid Generative Adversarial Networks for Deep MR to CT Synthesis Using

Unpaired Data

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«Biomedical Sciences» | B-167 to B-181

B-167 Christa König, Division of Pediatric Hematology/Oncology, Department of Pediatrics,Inselspital, Bern University Hospital, and Centre for Reviews and Dissemination, University of York, UK Time to Antibiotics and Clinical Outcomes in Fever and Neutropenia During Chemotherapy for Cancer, a Systematic Review

B-168 Gregory Lepeu, Center for Experimental Neurology, Department of Neurology,Inselspital, Bern University Hospital Cortical Excitability as a Marker of Epileptic Seizures Susceptibility in the Mouse Hippocampus

B-169* Rebeca Mozun, Institute of Social and Preventive MedicineSmoking Behaviour in Swiss Adolescent

B-170* Peter J. Neyer, Department of Clinical Chemistry, Inselspital, Bern UniversityHospital, and Institute of Laboratory Medicine, Kantonsspital Aarau Understanding the Function of Erythroferrone in Human Iron Metabolism

B-171* Maria Otth, Institute of Social and Preventive MedicinePulmonary Late Effects in Swiss Childhood Cancer Survivors After Hematopoietic Stem Cell Transplantation—A Report from the Swiss Childhood Cancer Survivor Study

B-172* Ranya Özcelik, Veterinary Public Health Institute, DCR-VPH, Vetsuisse Faculty BernInvestigating Opportunities for Community-Based Surveillance of Equines in Switzerland

B-173* Julia K. Prümmer, Division of Clinical Neurology, Small Animal Clinic, Department ofClinical Veterinary Science, Vetsuisse Faculty Bern Oligoclonal Bands in Dogs with Meningoencephalitis of Unknown Origin (MUO)

B-174 Katrina Rosenberger, Division of Animal Welfare, VPH Institute, Vetsuisse FacultyBern, University of Bern, and Centre for Proper Housing of Ruminants and Pigs, Agroscope, Tänikon Dairy and Dwarf Goats Differ in Their Preference for Familiar and Unfamiliar Humans

B-175 Alba Rudolf Vegas, Clinic of Reproductive Medicine, Department for Farm Animals,Vetsuisse Faculty Zurich Spatial Transcriptome Analysis of the Endometrium During the Period of Maternal Recognition of Pregnancy in the Mare

B-176 Kira Schmitt, Department for Small Animal Medicine, Vetsuisse Faculty ZurichTransmission Dynamics of ESBL, CPE and VRE Between Pets and Humans—Clinical Environment Versus Household

B-177* Andras Laszlo Soti, Department of Pediatric Pulmonology, Inselspital, BernUniversity Hospital Joint Effects of Prenatal Smoke Exposure and Polymorphisms in the MBL2 Gene on Cord Blood Levels of Mannose-Binding Lectin

B-178* Meng Tian, Department of Ophthalmology, Inselspital, Bern University HospitalEvaluation of Vascular Changes in Posterior Uveitis Using Swept-Source Widefield Optical Coherence Tomography Angiography

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B-179* Nicolas Waespe, Institute of Social and Preventive Medicine, University of Bern, and CANSEARCH Research Laboratory, University of Geneva

Incidence and Risk Factors for Early Second Neoplasms in Swiss Childhood Cancer Patients

B-180 Christoph Corin Willers, Division of Pediatric Respiratory Medicine, Department of Pediatrics, Inselspital, Bern University Hospital

New Quantification Method for Ventilation and Perfusion Defects from Functional Lung MRI in Pediatric Patients with Cystic Fibrosis

B-181 Kathrin Zürcher, Institute of Social and Preventive Medicine A Novel Approach to Estimate Tuberculosis Transmission at HIV Care Clinics in

Southern Africa

«Cell Biology» | B-182 to B-210

B-182 Paola Antonello, Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona

The Role of ACKR3 in B Cell Lymphoma Transmigration and Correlation with IgM Expression

B-183 Niccolò Bianchi, Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona

Dissecting miRNA Molecular Networks in Human T Helper Lymphocytes B-184* Mirjam Kiener, Urology, Department for BioMedical Research Characterisation of Bladder Cancer Drug Responses in Organoids and ex vivo

Models B-185 Laura Laloli, Institute for Infectious Diseases; Institute of Virology and Immunology

(IVI), Vetsuisse Faculty Bern; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

Characterization of the Innate Immune System in the Respiratory Epithelium of Human, Swine, and Bovine Origin During Influenza Virus Infection

B-186 Yu Larpin, Institute of Anatomy Bacterial Pore-Forming Toxin Pneumolysin: Cell Membrane Structure and

Microvesicle Shedding Capacity Determines Differential Survival of Immune Cell Types

B-187* Nathan Leborgne, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern, and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

Unrequired Function of the Cytosolic Serpin Serpinb1a in Homeostasis and Activity of Invariant Natural Killer T Cells

B-188* Marta Lewandowska, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern, and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern

Exploring Species Tropism of Zoonotic Flaviviruses in vitro B-189 Lijuan Ma, Endometriosis and Gynaecological Oncology, Department for BioMedical

Research, University of Bern, and Departments of Obstetrics and Gynaecology, Inselspital, Bern University Hospital

The Association Between Epithelial to Mesenchymal Transition and the Expression of Progesterone and Estrogen Receptors in Endometriosis Tissue

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B-190 Nikita Markov, Institute of Pharmacology Altered Polarisation Status of OPA1-Deficient Macrophages Is Mediated by Metabolic

Rewiring of Macrophages B-191 Annelies Müller, Institute for Infectious Diseases Pneumococcal Growth and Capsule Size in Human Cerebrospinal Fluid Depends on

Serotype B-192 Carmen Muñoz-Maldonado, Department of Radiation Oncology, Inselspital, Bern

University Hospital, and Radiation Oncology, Department for BioMedical Research, University of Bern

Screening for Synthetic Interactions in CHK2-Deficient Cancers B-193* Samara Naim, Institute of Pharmacology Non-Apoptotic Roles of the BCL-2 Family Member BOK B-194* Nicolas Jan Niklaus, Institute of Pathology DMTF1β-Induced Autophagy Enhances Migration and Invasion of Breast Cancer Cell

Lines B-195 Shuang Peng, Institute of Pharmacology Discovery of RhoH as a Negative Regulator in Neutrophil Extracellular Trap

Formation B-196 Chiara Pozzato, Institute of Pharmacology The Role of Focal Adhesion Kinase in Lung Cancer Progression B-197 Sreoshee Rafiq, Institute of Pathology Chaperone-Mediated Autophagy and Its Role in Acute Myeloid Leukemia Biology B-198 Pascal Rossatti, Biotechnology Institute Thurgau (BITg) at the University of

Konstanz, Kreuzlingen Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular

Invaginations of the Plasma Membrane B-199 Viviana Rubino, Tumor-Immunology, Department for BioMedical Research,

University of Bern, and Department of Medical Oncology, Inselspital, Bern University Hospital

IL-21 Secreted by CD4 T Cells Reduces Leukemia Stem Cell Function in Human and Murine Acute Myeloid Leukemia

B-200 Fatemeh Safari, Bone Biology & Orthopaedic Research, Department for BioMedical Research

Noggin as a Regulator of Bone Remodelling B-201* Guerric P. B. Samson, Biotechnology Institute Thurgau (BITg) at the University of

Konstanz, Kreuzlingen Flotillin-2 Promotes DC Trafficking to Lymph Nodes B-202 Zahra Sattari, Gastroenterology/Mucosal Immunology, Department for BioMedical

Research, University of Bern, and Agroscope, Bern Polyfermenthealth—Linking Bacterial Diversity in Fermented Food to Metabolic

Health B-203* Olivier Pascal Schären, Institute for Infectious Diseases Muropeptide Auxotrophic Strains Are Efficient Intestinal Colonizers

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B-204 Kristina Seiler, Institute of Pathology, University of Bern, and Department ofImmunology, Scripps Research, La Jolla, USA Role of Hexokinase 2 and 3 in Energy Metabolism, Myeloid Differentiation and Cancer Development

B-205 Basma Tarek, Institute of Animal Pathology, Department of Infectious Diseases andPathobiology, Vetsuisse Faculty Bern Identification of Host Factors Involved in Clostridium perfringens Beta Toxin-Mediated Damage in Endothelial Cells

B-206 Igor Tokarchuk, Institute of PathologyIncreased LAMP2A Levels Are Associated with Increased Breast Cancer Cell Survival and Shorter Disease-Free Survival of Breast Cancer Patients

B-207* Tommaso Virgilio, Institute for Research in Biomedicine, Università della Svizzeraitaliana, Bellinzona In vivo Characterization of Melanoma Dissemination Through the Lymphatic System

B-208 Zhang Yang, Thoracic Surgery, Department for BioMedical ResearchA Kinome CRISPR Screen in FGFR-Amplified Lung Cancer

B-209 Wen Jie Yeoh, Institute of PathologyThe Inositol Phosphatase SHIP Restrains Type 2 Innate Lymphoid Cell-Induced Airway Inflammation

B-210 Xingshuo Zhang, Tissue Engineering for Orthopaedics & Mechanobiology,Orthopaedics, Department for BioMedical Research Spheroid Formation for Cell Expansion of the Angiopoietin Receptor-1(aka Tie2) Positive Cells from the Intervertebral Disc

«Molecular Biology & Biochemistry» | B-211 to B-242

B-211* Iris Hug, Institute of Cell BiologyCharacterisation of Small RNA-Producing DNA Minicircles and Genome Organization in Paramecium tetraurelia

B-212* Advaitha Iyer, Institute of Biochemistry and Molecular MedicineFunctional Analysis of the Endoplasmic Reticulum Membrane Protein Complex (EMC) in T. brucei

B-213* Aurelio Leandro Jenni, Institute of Biochemistry and Molecular MedicineIs GPI2 Required for GPI Anchor Biosynthesis?

B-214* Nicole Patrizia Kadzioch, Division of Neurological Sciences, DCR-VPH, VetsuisseFaculty Bern Lysine Residues of the Canine Distemper Virus Matrix Protein Regulate Membrane Association and Budding Activity

B-215 Yuanzhen Liu, Institute of Bee Health, DCR-VPH, Vetsuisse Faculty BernComparative Analyses of the Odorant Receptor Genes in Small Hive Beetles

B-216* Alessio Loffreda, Institute of Biochemistry and Molecular MedicineCLDP43, a Novel Cardiolipin Synthase-Dependent Protein Affecting Cardiolipin Synthesis and Mitochondrial Integrity in T. brucei

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B-217 Alessandro Marazza, Institute for Research in Biomedicine, Università della Svizzeraitaliana, Bellinzona Endoplasmic Reticulum and Lysosomal Quality Control of Four Nonsense Mutants of Iduronate 2-Sulfatase Linked to Hunter’s Syndrome

B-218 Julia Aline Moor, Institute for Infectious DiseasesCarriage of Extended-Spectrum Cephalosporin and Colistin Resistant Escherichia coli in Pigs Is Transient and Decreases with Increasing Age

B-219 Francis Muchaamba, Institute for Food Safety and Hygiene, Vetsuisse FacultyZurich Listeria monocytogenes Comes in Different Shades: Clinical and Food Associated Strains Vary in Virulence, Stress Resistance, and Carbon Source Metabolism

B-220* Merve Mutlu, Institute of Animal Pathology, Department of Infectious Diseases andPathobiology, Vetsuisse Faculty Bern Loss of ERCC6L2 Restores Homology-Directed DNA Repair and Causes PARPi Resistance in BRCA1-Deficient Mammary Tumor Cells

B-221 Damian Nydegger, Department of Nephrology and Hypertension, Inselspital, BernUniversity Hospital, and Nephrology and Hypertension, Department for BioMedical Research, University of Bern The Role of Mitochondrial SLC Solute Carriers in Colon Cancer Progression

B-222* Jaime Osuna Luque, Institute of Cell Biology, University of Bern, and Institut degénétique et de biologie moléculaire et cellulaire IGBMC, University of Strasbourg, France Analysis of the Transcriptional Basis of Natural Transdifferentiation in C. elegans

B-223 Oluwaseun Oyewole, Institute for Infectious DiseasesPacBio SMRT Amplicon Sequencing for Strain Based Pneumococcal Resolution

B-224* Taisia Polidori, RNA & Cancer, Department for BioMedical Research, University ofBern, and Department of Medical Oncology, Inselspital, Bern University Hospital CRISPR/Cas9 Functional Screens for Long Non-Coding RNAs in Lung Cancer

B-225* Carlos Pulido Quetglas, RNA & Cancer, Department for BioMedical Research,University of Bern, and Department of Medical Oncology, Inselspital, Bern University Hospital Bioinformatics Roadmap to Accurate High Throughout Screens

B-226 Nicole Raad, Department of Chemistry and BiochemistryA Small ncRNA Regulates Fimbriation and Biofilm Formation in Stationary Phase E. coli

B-227 Sandhya Krishnan Radha Krishnan, Institute of Biochemistry and MolecularMedicine Trypanosoma cruzi Serine Hydrolases: A Parasite-Host Lipid Crosstalk

B-228 Thomas Roder, Interfaculty Bioinformatics Unit, Department of Biology, University ofBern, and Agroscope, Federal Department of Economic Affairs, Education and Research EAER, Switzerland Polyfermenthealth

B-229 Lorenz Timo Ryser, Interfaculty Bioinformatics Unit, Department of Biology,University of Bern, and Agroscope, Federal Department of Economic Affairs, Education and Research EAER, Switzerland Biogenic Amine Formation in Morganella morganii Isolated from Cheese—Linking Phenotype to Genomic Data

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B-230 Jonathan Save, Department of Intensive Care Medicine, Inselspital, Bern UniversityHospital, and Department of Fundamental Microbiology, University of Lausanne Controlling Staphylococcus aureus Infection Through Phage Therapy in a Model of Experimental Endocarditis

B-231 Dominic Schärer, Department of Clinical Chemistry, Inselspital, Bern UniversityHospital LC-MS/MS Method for Quantification of Folate Metabolites in Human Plasma

B-232 Jens Alexander Schröder, Institute of Plant SciencesInvestigation of Small RNA Movement Within Arabidopsis Female Ovules

B-233 Therese Solberg, Institute of Cell BiologyCharacterization of the Developmental Piwi Protein Ptiwi08 in Paramecium tetraurelia

B-234 Silvio Steiner, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern,and Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern Investigating the Role of Stress Granules as an Antiviral Defense Mechanism

B-235 Isabel Stürmer, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern;Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern; Institute for Infectious Diseases Genome-Wide CRISPR Inactivator and Activator Screen to Identify Host Determinants Involved in Interactions with Influenza D Virus

B-236 Andrea Timpanaro, Hematology/Oncology, Department for BioMedical ResearchSurfaceome Profiling of Rhabdomyosarcoma for New CAR T Cell-Based Therapy

B-237 Louis Tirot, Institute of Plant SciencesOver-Expression of MET2a and MET2b Affect Arabidopsis thaliana Flowering Time

B-238 Thao Tran, Institute of Virology and Immunology (IVI), Vetsuisse Faculty Bern, andDepartment of Infectious Diseases and Pathobiology, Vetsuisse Faculty Bern Expanding Synthetic Genomics Pipeline to Large RNA Viruses

B-239 Corinne von Känel, Department of Chemistry and BiochemistryElucidating the Motor for Mitochondrial Protein Import in Trypanosoma brucei

B-240 Joseph Wambui, Institute for Food Safety and Hygiene, Vetsuisse Faculty ZurichUncovering New Nisin Resistance Mechanisms in Listeria monocytogenes Through Phenome and Genome-Based Analysis

B-241 Christoph Wenger, Department of Chemistry and BiochemistryThe Protein Translocase in the Inner Mitochondrial Membrane of Trypanosoma brucei

B-242 Tsering Wüthrich, Institute for Infectious DiseasesA Bioinformatic Workflow for Direct Staphylococcus Species Assignment from Metagenetic Sequencing in Nose Swabs of Children with Cystic Fibrosis

Note: Please remove posters of Session B during the afternoon Coffee Break, between 15h00 and 15h30.

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GCB Symposium 2020 | Program: Afternoon Sessions

DCB, Room U113, basement

15h00–15h30 | Coffee Break (Mensa Bühlplatz) & Poster Viewing/ Poster Removal

Posters of Session B will be removed during the afternoon Coffee Break

15h30–16h00 | GCB Award for Best PhD Thesis

Chair: Prof. Dr. Frank Stüber, President GCB

16h00–17h00 | Keynote Lecture

Prof. Dr. Sylviane Muller School of Biotechnology, University of Strasbourg, France «Mechanism-Guided Novel Therapies for Treating Inflammatory Diseases» Abstract: see p. 3

Chair: PD Dr. Monica Schaller, Coordinator GCB

17h00 | Closing Remarks

Prof. Dr. Frank Stüber, President GCB

17h15 | Apéro

Everybody is invited to join in.