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GEMSS: Grid-Enabled Medical Simulation Services
Healthgrid Cluster Meeting
Project Overview:
Profile from CORDISConsortiumProject Goals / ObjectivesGEMSS System DesignMedical ApplicationsClustering
IST-2001-37153
GEMSS Project Profile (Cordis)Project Acronym: GEMSSTitle: GRID-enabled Medical Simul. ServicesSubject Index : Policies; Legislation, Regulations;Information Processing,
Information Systems; Electronics, Microelectronics
Start Date: 2002-09-01 End Date: 2005-02-28 Duration: 30 MsProject Status: Accepted
Project Cost: 3.59 million € Funding: 2.63 million €
Programme Type: 5th FWP (Fifth Framework Programme)Programme Acronym : ISTSubprogramme Area: Cross Programme Actions (CPA) –
CPA9: Grid test beds, deployment and technologies
Project Reference: IST-2001-37153Contract Type: CSC (Cost-sharing contracts)
GEMSS ConsortiumNo Partner Role Country Specific Expertise
1 NEC CC&C R.L.
UK (Germany)
2 MPI P Germany
3 ISS P Austria
4 USFD P
STH S
UK
5 AEA P UK
6 IT- PInnovation
UK
7 CRID P Belgium
8 ASD A Germany
9 IDAC A Ireland
10 IBMTP A Austria
Simulation/Imaging SW
Grid Software /solutions
Bio-numeric modelling
Medical Expertise
Legal Aspects
Legend: C – Co-ordinator P – Principal Contractor S – Subcontractor A – Associate Contractor
1. Install an extendible, interoperable and collaborative
testbed for GRID-enabled medical application
services,
2. Demonstrate the medical significance of the GEMSS
models,
3. Demonstrate the functionality of the GRID-
infrastructure,
4. Open a business model for future commercial
exploitation.
The main goals of GEMSS are :
Simulation portal
Medical simulation service Portal + networked compute resources
Pre- & Post-processing
User-site (SW installed)
GRID SW
GRID SW (interface)
Applications SW
GRID SW (service use)
Internetor Intranet
Internetor Intranet
Could also be movedto the services portal
Simulation Service System
A general overview / A general overview / possible scenariopossible scenario
GEMSS Project Objectives
GEMSS will demonstrate that the Grid can be used to provide medical practitioners and researchers with access to advanced simulation and image processing services for improved pre-operative planning and near real-time surgical support.
The GEMSS will build on top of existing Grid technologies, maintaining compliance with standards thereby ensuring future extensibility and interoperability, to provide support for authorisation, workflow, security, error detection and recovery.
Test-bed to evaluate & validate the GEMSS environment, including its integration into the end-users working environments.
GEMSS aims to anticipate privacy, security and other legal concerns by examining and incorporating into its Grid services the latest laws and EU regulations related to providing medical services over the Internet.
GEMSS System Design
Generic GRID-services: build on existing GRID and WEB technologies like OGSA, Web services, Jini and Corba, service interaction models, protocols & interfaces, QoS (time critical services), security models compliant with European legal issues, fail-over and recovery from errors, workflow and service orchestration techniques for time-critical processes, medical GRID portals, PSEs, application servers.
Collaborative tools: tele-support, tele-consulting.
Medical service applications: Numerical modelling, based on existing software packages such as CFX and EASA, High Performance Computing (HPC) simulation, FE analysis, Advanced image processing.
Application Layer
CollectiveLayer
Resource Layer
FabricLayer
Grid ArchitectureGrid Architecture
Applications, Portals, Environments
Higher Services, APIs, Protocols
APIs, Protocols, SDKs
Computers, Networks, Devices
Application Layer
CollectiveLayer
Resource Layer
FabricLayer
Grid ArchitectureGrid Architecture
Applications, Portals, Environments
Higher Services, APIs, Protocols
APIs, Protocols, SDKs
Computers, Networks, DevicesGlobus toolkit
Application Layer
CollectiveLayer
Resource Layer
FabricLayer
Grid ArchitectureGrid Architecture
Applications, Portals, Environments
Higher Services, APIs, Protocols
APIs, Protocols, SDKs
Computers, Networks, Devices
Condor
Application Layer
CollectiveLayer
Resource Layer
FabricLayer
Grid ArchitectureGrid Architecture
Applications, Portals, Environments
Higher Services, APIs, Protocols
APIs, Protocols, SDKs
Computers, Networks, Devices
Legion
Application Layer
CollectiveLayer
Resource Layer
FabricLayer
Grid ArchitectureGrid Architecture
Applications, Portals, Environments
Higher Services, APIs, Protocols
APIs, Protocols, SDKs
Computers, Networks, Devices
UNICORE
Application Layer
CollectiveLayer
Resource Layer
FabricLayer
Grid ArchitectureGrid Architecture
Applications, Portals, Environments
Higher Services, APIs, Protocols
APIs, Protocols, SDKs
Computers, Networks, Devices
CondorUNICORE
Which one to use?Which one to use?
Legion
Globus toolkit
GEMSS: Medical Applications
Test-bed Applications
(1) Maxillo-facial surgery simulation.
(2) Neuro-surgery support.
(3) Radio-surgery simulation.
(4) Inhaled drug-delivery simulation.
(5) Cardio-vascular system simulation.
(6) Advanced image reconstruction.
Phase I:Halo positioning
Maxillo-facial Surgery Simulation
During maxillo-facial surgery a steel device is tightly fixed to the head by special screws. These screws deform the skull which becomes clearly visible as a result of a parallel finite element analysis. The goal is to provide a virtual planning space for the optimisation the fixation and distraction procedures.
Partners: NEC MPI
Phase II:Distraction Procedure
Test-bed Applications
(1) Maxillo-facial surgery simulation.
(2) Neuro-surgery support.
(3) Radio-surgery simulation.
(4) Inhaled drug-delivery simulation.
(5) Cardio-vascular system simulation.
(6) Advanced image reconstruction.
Neuro Surgery Support
Prediction of the brain shift during neurosurgery is important to provide co-ordinates for the surgical navigation. In GEMSS a robust and precise approach based on non-linear image registration will be implemented in a Grid environment.
Partner(s): MPI
GEMSS: Medical Applications
Test-bed Applications
(1) Maxillo-facial surgery simulation.
(2) Neuro-surgery support.
(3) Radio-surgery simulation.
(4) Inhaled drug-delivery simulation.
(5) Cardio-vascular system simulation.
(6) Advanced image reconstruction.
Radio-surgery simulation
Revised treatment plan simulated - different beam weighting and orientationRAPT simulation now shows better coverage - differs from conventional treatment analysisNew treatment more likely to be successful.
Partner(s): IT-Innovation, USFD
GEMSS: Medical Applications
Test-bed Applications
(1) Maxillo-facial surgery simulation.
(2) Neuro-surgery support.
(3) Radio-surgery simulation.
(4) Inhaled drug-delivery simulation.
(5) Cardio-vascular system simulation.
(6) Advanced image reconstruction.
Inhaled Drug-Delivery Simulation
Take-up of the Cophit project –
A combination of computational fluid dynamics and 1-dimensional models to optimise delivery of inhaled drugs to the lung.
Partner(s): USFD, AEA, ASD
GEMSS: Medical Applications
Test-bed Applications
(1) Maxillo-facial surgery simulation.
(2) Neuro-surgery support.
(3) Radio-surgery simulation.
(4) Inhaled drug-delivery simulation.
(5) Cardio-vascular system simulation.
(6) Advanced image reconstruction.
Cardio-vascular System Simulation
A compartmental approach and coupled structural mechanics and fluid dynamics will be applied to simulate the entire cardio-vascular system.
Partner(s): USFD, AEA, ASD, IDAC
GEMSS: Medical Applications
Heart-valve example kindly provided by the BLOODSIM project.
Advanced Image Reconstruction
Entropy-based parallel Projection Image Reconstruction for SPECT.
The medical image reconstruction system is based on a service oriented architecture to provide clients with advanced fully 3D image reconstruction services running transparently on remote parallel computers.
Partner(s): ISS, IBMTP
Test-bed Applications
(1) Maxillo-facial surgery simulation.
(2) Neuro-surgery support.
(3) Radio-surgery simulation.
(4) Inhaled drug-delivery simulation.
(5) Cardio-vascular system simulation.
(6) Advanced image reconstruction.
GEMSS: Medical Applications
Hospital A
Internet
Agent
Reconstruction Service
Reconstruction Service
...
GRID
...
Hospital Z
Healthgrid Cluster Activities
GEMSS contributions:• Participation in the GGF.• Participation in GridStart.• Establish contact with related projects to
identify common interests and synergies.• Consolidation of technical developments.• Identification of possible tool sharing.• Interoperability and standardisation efforts.• Common dissemination in health-related
events.
Suggestions for Clustering
• CROSSGRID
As the first application, a Grid-based prototype system for pre-treatment planning in vascular interventional and surgical procedures will be developed through real-time interactive simulation of vascular structure and flow. The system consists of a distributed real-time simulation environment, in which a user interacts in Virtual Reality (VR). A 3D model of the arteries, derived using medical imaging techniques, will serve as input to a real-time simulation environment for blood flow calculations. The user will be allowed to change the structure of the arteries, thus mimicking a surgical procedure and the effects of this adaptation will be analysed in real time while the results are presented to the user in a virtual environment.
Suggestions for Clustering
• CROSSGRID + GEMSS
common interests:
Simulation/visualisation,Medical LBA(Lattice Boltzmann for scan data)
Suggestions for Clustering
• EUROGRID (Bio/Meteo/CAE-GRID)The objectives of the EUROGRID project are:
• To establish a European GRID network of leading High Performance Computing centres from different European countries.
• To operate and support the EUROGRID software infrastructure. The EUROGRID software will use the existing Internet network and will offer seamless and secure access for the EUROGRID users.
• To develop important GRID software components and to integrate them into EUROGRID (fast file transfer, resource broker, interface for coupled applications and interactive access).
• To demonstrate distributed simulation codes from different application areas (Biomolecular simulations, Weather prediction, Coupled CAE simulations, Structural analysis, Real-time data processing).
• To contribute to the international GRID development and to liase with the leading international GRID projects.
• To productise the EUROGRID software components. After project end the EUROGRID software will be available as supported product.
Suggestions for Clustering
• EUROGRID + GEMSS
common interests:
UNICOREBio-GRIDHPC GRID
GEMSS: Contact & Info
Contact: [email protected]
Dr. Jochen Fingberg
C&C Research Laboratories
NEC Europe Ltd.
Tel. +49 2241 92520
Project site:http://www.gemss.de
Cordis: http://dbs.cordis.lu