Genitourinary Block (2)

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    ONNAZLI0910

    GENITOURINARY BLOCK

    CASE 1

    A 60 years old man presents to the clinic with cola-coloured urine and flank pain. After taking a

    careful history, you learn that the man has a low-grade fever and has lost 10 pounds over pastmonth. He is a chronic smoker. PE reveals a large mass in the left kidney and lab findings suggest

    secondary polycythaemia.

    1. State your provisional diagnosis2. State 1 condition associated with your provisional diagnosis3. Explain pathophysiology of cola-coloured urine4. Relate polycythaemia with your diagnosis5. State pathological findings in the left kidney

    CASE 2

    A 65 years old malay man with 20 years history of type 2 DM presents for a nephrology consult after

    his primary care physician found a progressive increase of proteinuria in recent lab studies. The lab

    studies also revelas hyperlipidaemia and hypercholestrolaemia. Through physical investigation, there

    are bilateral retinopathy and oedema in both leg. He was diagnosed to have diabetic nephropathy

    1. Explain briefly the metabolism of glucose2. State the pathogenesis of diabetic nephropathy3.

    List HPE findings that can be found in this patients glomeruli

    4. What do you understand by diabetic triopathy5. Explain principle of management for the patient with diabetic nephropathy

    CASE 3

    A 25 years old man presents with blood in his urine. Further history reveals that his father had died

    of kidney in his late 30s and the patient is very concerned about having same fate. PE reveals a blood

    pressure of 170/110 mmHg and bilateral palpable renal masses. He was sent to CT scan and he was

    diagnosed to have polycystic kidney disease

    1. Classify polycystic kidney disease2. State mode of inheritance of both disease above3. List the pathology of polycystic kidney disease4. List expected findings in patients CT scan5. patient is very concerned about having same fate, describe concept of truth telling and

    state 1 other ethical issue involve in this kind of situation

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    RAPID KL QUESTION

    1. With the aid of diagram, briefly describe congenital abnormalities of kidney:a) Horse-shoe kidneyb) Right pelvic kidneyc) Discoid kidneyd) Left supernumerary kidney

    2. With the aid of diagram, briefly describe congenital abnormalities of ureter:a) Complete double ureterb) Bifid ureter with double kidneyc) Partial double ureterd) Bifid ureter with divided kidney

    3. With the aid of diagram, briefly describe congenital abnormalities of allatois:a) Urachal fistulab) Urachal cystc) Urachal sinus

    4. Define glomerulonephritis5. Explain the pathogenesis of glomerulonephritis6. List 10 manifestations of uraemia

    CASE 4

    A 15 years old Chinese presents to emergency room frightened by his red-colored urine. Upon taking

    a complete history, you learn that he is suffering from a strange flu-like syndrome that began 2 days

    earlier consisting of vomiting, myalgias, athralgia and fever. Serum studies reveal increase serum IgA

    levels and normal serum complement levels

    1. State your provisional diagnosis2. State the pathogenesis of the disease you stated above3. State 4 theories of autoimmunity4. State 1 treatment in this patient

    CASE 5

    A 40 years woman presents to emergency room due to colicky abdominal pain and flank pain

    radiating toward her groin. History reveals that she has seen large amounts of blood in her urine and

    that she had history of recurrent UTI. She was diagnose to have urinary stone

    1. State further history you would like to ask to support your diagnosis2. State 4 types of stone and the related illness3. What do you mean by colicky abdominal pain? State the pathogenesis4. List complications that arise from this condition5. What are the theories of formation of urinary stones?

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