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Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

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Page 1: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea

Sexually Transmitted Disease Surveillance 2007

Division of STD Prevention

Page 2: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Rates: United States, 1941–2007 and the Healthy People 2010 target

Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000 population.

0

100

200

300

400

500

1941 46 51 56 61 66 71 76 81 86 91 96 2001 06

Rate (per 100,000 population)

Gonorrhea2010 Target

Page 3: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Rates: Total and by sex: United States, 1988–2007 and the Healthy People 2010 target

Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000 population.

Rate (per 100,000 population)

MaleFemaleTotal2010 Target

0

80

160

240

320

400

1988 90 92 94 96 98 2000 02 04 06

Page 4: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Rates by region: United States, 1998–2007 and theHealthy People 2010 target

Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000 population.

Rate (per 100,000 population)

WestMidwestNortheastSouth2010 Target

0

60

120

180

240

300

1998 99 2000 01 02 03 04 05 06 07

Page 5: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Rate per 100,000population

Guam 82.4

Puerto Rico 8.2

Virgin Is. 63.5

<=19.0

19.1-100.0

>100

(n= 8)

(n= 25)

(n= 21)

VT 10.3NH 10.5MA 41.9RI 37.7CT 66.4NJ 69.6DE 151.5MD 120.5DC 408.1

236.7

86.4

82.1148.3

85.8 71.0

129.0

190.5

51.3

18.3

162.2 139.2

64.7

82.682.0

259.7

8.9

153.4

66.9

285.7

169.0

12.9

81.194.4

91.9

91.7

188.2

18.2

183.5

134.9

33.4

102.1

239.0

33.4

158.4

136.4

32.282.0

57.1

51.1

121.5

15.7

Gonorrhea — Rates by state: United States and outlying areas, 2007

Note: The total rate of gonorrhea for the United States and outlying areas (Guam, Puerto Rico and Virgin Islands) was 117.4 per 100,000 population. The Healthy People 2010 target is 19.0 cases per 100,000 population.

Page 6: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Rates by county: United States, 2007

Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000 population.

Rate per 100,000population

<=19.0 (n= 1,305)

19.1-100.0 (n= 1,099)

>100.0 (n= 736)

Page 7: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Age- and sex-specific rates: United States, 2007

Men Rate (per 100,000 population) Women

Age750 600 450 300 150 0 0 150 300 450 600 750

5.9 33.110-14286.0 647.915-19

450.1 614.520-24305.1 287.125-29

181.5 125.230-34119.5 60.535-39

86.6 30.840-4450.2 12.145-54

17.7 3.055-644.0 0.465+

113.9 123.8Total

Page 8: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Age-specific rates among women 15 to 44 years of age:United States, 1998–2007

Rate (per 100,000 population)

15-19 20-2425-29 30-3435-39 40-44

0

200

400

600

800

1,000

1998 99 2000 01 02 03 04 05 06 07

Page 9: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Age-specific rates among men 15 to 44 years of age:United States, 1998–2007

Rate (per 100,000 population)

15-19 20-2425-29 30-3435-39 40-44

0

150

300

450

600

750

1998 99 2000 01 02 03 04 05 06 07

Page 10: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Rates by race/ethnicity: United States, 1998–2007

0

180

360

540

720

900

1998 99 2000 01 02 03 04 05 06 07

Rate (per 100,000 population)

American Indian/AK NativeAsian/Pacific IslanderBlackHispanicWhite

Page 11: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonorrhea — Cases by reporting source and sex: United States, 1998–2007

Cases (in thousands)

non-STD Clinic Malenon-STD Clinic FemaleSTD Clinic MaleSTD Clinic Female

0

40

80

120

160

200

1998 99 2000 01 02 03 04 05 06 07

Page 12: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Positivity (%)

Puerto Rico 0.1

Virgin Is. 3.6

See*

<1.0

1.0-1.9

>=2.0

(n= 8)

(n= 24)

(n= 12)

(n= 9)

VT 0.1NH 0.1MARICT 0.6NJ 1.4DE 1.1MDDC

3.8

0.4

0.8 2.0

1.1 0.6

1.5

2.7

0.8

0.2

1.6 1.6

0.6

0.90.7

2.2

0.1

1.7

0.5

3.3

1.3

0.8

0.90.8

0.9

0.5

1.5

1.8

0.8

0.9

2.40.9

2.8

1.11.2

0.5

4.9

0.2

Gonorrhea — Positivity among 15- to 24-year-old women tested in family planning

clinics by state: United States and outlying areas, 2007

*States/areas not meeting minimum inclusion criteria.Note: Includes states and outlying areas that reported positivity data on at least 500 women aged 15-24 years screened during 2007.

SOURCE: Gonorrhea Prevalence Monitoring Project (Regional Infertility Prevention Projects); Office of Population Affairs; Local and State STD Control Programs; Centers for Disease Control and Prevention

Page 13: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonococcal Isolate Surveillance Project (GISP) — Prevalence of ciprofloxacin resistant Neisseria gonorrhoeae by GISP site, 2004-2007

Note: Not all clinics participated in GISP for the last 4 years. Sites include: ALB=Albuquerque, NM; ATL=Atlanta, GA; BAL=Baltimore, MD; BHM=Birmingham, AL; CHI=Chicago, IL; CIN=Cincinnati, OH; CLE=Cleveland, OH; DAL=Dallas, TX; DEN=Denver, CO; DTR=Detroit, MI; GRB=Greensboro, NC; HON=Honolulu, HI; KCY=Kansas City, MO; LAX=Los Angeles, CA; LBC=Long Beach, CA; LVG=Las Vegas, NV; MIA=Miami, FL; MIN=Minneapolis, MN; NOR=New Orleans, LA; NYC=New York City, NY; OKC=Oklahoma City, OK; ORA=Orange County, CA; PHI=Philadelphia, PA; PHX=Phoenix, AZ; POR=Portland, OR; SDG=San Diego, CA; SEA=Seattle, WA; SFO=San Francisco, CA; and TRP=Tripler Army Medical Center, HI

0%

25%

50%

'04 '05 '06 '07

QRNG Prevalence

BHM PHX

LBC LAX

ORA

SDG

SFO DEN

MIA

ATL

HON TRP

CHI

NOR

BAL

DTR MIN

KCY LVG

ALB

NYC

GRB

CIN

CLE

OKC

POR

PHI

DAL

RIC

SEA

Page 14: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonococcal Isolate Surveillance Project (GISP) — Penicillin, tetracycline, and ciprofloxacin resistance among GISP isolates, 2007

Note: PenR=penicillinase producing N. gonorrhoeae and chromosomally mediated penicillin-resistant N. gonorrhoeae; TetR=chromosomally and plasmid mediated tetracycline-resistant N. gonorrhoeae; QRNG=ciprofloxacin resistant N. gonorrhoeae.

Page 15: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonococcal Isolate Surveillance Project (GISP) — Percent of Neisseria gonorrhoeae isolates with resistance or intermediate resistance to ciprofloxacin,

1990–2007

Note: Resistant isolates have ciprofloxacin MICs ≥ 1 µg/ml. Isolates with intermediate resistance have ciprofloxacin MICs of 0.125 - 0.5 µg/ml. Susceptibility to ciprofloxacin was first measured in GISP in 1990.

Percent

ResistanceIntermediate resistance

0

4

8

12

16

1990 91 92 93 94 95 96 97 98 99 2000 01 02 03 04 05 06 07

Page 16: Gonorrhea Sexually Transmitted Disease Surveillance 2007 Division of STD Prevention

Gonococcal Isolate Surveillance Project (GISP) — Percent of Neisseria gonorrhoeae isolates with resistance to ciprofloxacin by sexual behavior,

2001–2007

Percent

Heterosexual menMen who have sex with men (MSM)

0

8

16

24

32

40

2001 2002 2003 2004 2005 2006 2007