Upload
tony-chunn
View
223
Download
0
Embed Size (px)
Citation preview
What is Hyperplasia?What is Hyperplasia?
Hyperplasia is a fancy way of saying Hyperplasia is a fancy way of saying
abnormal increase in cell numbers or cell abnormal increase in cell numbers or cell
numbers "gone wild" leading to a size numbers "gone wild" leading to a size
increase of the affected tissue or organ; it increase of the affected tissue or organ; it
can also be used as another term for can also be used as another term for
benign growth, or tumor.benign growth, or tumor.
Case HistoryCase History
Person requested help on koi forum Person requested help on koi forum for fish that had abnormal growthsfor fish that had abnormal growths Pond is 400 gallonsPond is 400 gallons Problem started 3 years ago with Problem started 3 years ago with
fish #1fish #1 Tumor grew, then fell offTumor grew, then fell off
Additional DetailsAdditional Details
Other Koi and goldfish started to Other Koi and goldfish started to develop growths develop growths
Small amount of algae on rocksSmall amount of algae on rocks Water analysis:Water analysis:
pH is normal, pH is normal, KH 120, KH 120, Nitrite 0, Nitrite 0, Nitrate 20Nitrate 20
ObservationsObservations
Fish eat and act normalFish eat and act normal
Pond owner originally thought it Pond owner originally thought it
was parasite relatedwas parasite related
Bumps are hardBumps are hard
My SuggestionsMy Suggestions
Pond is over crowded, more water changesPond is over crowded, more water changes
Possibility of Acriflavine for LymphocystisPossibility of Acriflavine for Lymphocystis Lymphocystis is a viral disorderLymphocystis is a viral disorder
Acriflavine (surface bactericide)Acriflavine (surface bactericide)
This treatment wouldn’t work on cancers or This treatment wouldn’t work on cancers or
hyperplasiahyperplasia
Lymphocystis CellsLymphocystis Cells on a Slideon a Slide
((Picture from KoivetPicture from Koivet))
Hyperplasia can be confused for Hyperplasia can be confused for lymphocystis (increase in cell size), and lymphocystis (increase in cell size), and various bacterial or fungal infections. various bacterial or fungal infections.
Lymphocystis usually appears whitish in Lymphocystis usually appears whitish in color, and distinct clusters of enlarged cells color, and distinct clusters of enlarged cells can be easily seen which have a visibly can be easily seen which have a visibly enlarged blood supply system supporting enlarged blood supply system supporting the rapidly expanding lymphocystis cellsthe rapidly expanding lymphocystis cells
Hyperplasia or Lymphocystis?
Many irritants can cause hyperplasiaMany irritants can cause hyperplasia Chemical irritantsChemical irritants
Toxic pollutantsToxic pollutants
Pond decoration or structures Pond decoration or structures
Aerosol spraysAerosol sprays
Open wound from injury, abrasions etc.Open wound from injury, abrasions etc.
Suspended particles in the waterSuspended particles in the water
Causes of Hyperplasia
Cure and preventionCure and prevention
Hyperplasia, will not be "cured" by Hyperplasia, will not be "cured" by
antibiotics or other treatments. In fact, antibiotics or other treatments. In fact,
the application of such medications the application of such medications
may have caused the hyperplasia to may have caused the hyperplasia to
begin with, or even stimulated more begin with, or even stimulated more
such growth.such growth.
Transmission to Humans?Transmission to Humans?
Researcher handled experimentally Researcher handled experimentally
infected fishinfected fish
Developed multiple warts on handsDeveloped multiple warts on hands
No viral cell comparison doneNo viral cell comparison done
Warts disappeared after working Warts disappeared after working
mixing concrete. Cause - basic pH?mixing concrete. Cause - basic pH?
Case UpdateCase Update
Koi have worsenedKoi have worsened
PO has not tried AcriflavinePO has not tried Acriflavine
Fish still act normal, have appetitesFish still act normal, have appetites
If I have further contact, I’ll If I have further contact, I’ll
recommend removing any sharp recommend removing any sharp
objects in addition to water changesobjects in addition to water changes
Lessons LearnedLessons Learned
Don't assume lesions are LymphocystisDon't assume lesions are Lymphocystis
Cause may be viral or environmentalCause may be viral or environmental
Not all skin growths are treatableNot all skin growths are treatable
Wear gloves to protect yourself Wear gloves to protect yourself
CreditsCredits
http://www.aquarticles.com/http://www.aquarticles.com/
Dr. Adrian Lawler,Dr. Adrian Lawler,P.O. Box 48,P.O. Box 48,
Ocean Springs.Ocean Springs.MS 39566MS 39566
U.S.A. U.S.A.