1
income (p 0.012). Conclusion: We concluded that there is a low level of knowledge among caregivers of children 13 years old in reference to child car seat safety laws and guidelines in PR. Future efforts should be directed towards improving population knowledge about the correct use of child car safety seats. e HYPOGLYCEMIA, AN UNCOMMON BUT REAL COMPLICATION OF STANDARD HYPERKALMIA TREATMENT. Y.C. Huang, Department of Emergency Med- icine, Chiayi Christian Hospital, Chiayi City, TAIWAN. Introduction: Hyperkalemia is life-threatening and requires im- mediate treatment. A combination of 25 g glucose and 10 units regular insulin given intravenously over 15–30 min is suggested as part of the standard treatment for hyperkalemia in Advanced Cardiac Life Support (ACLS); however, no precaution has been mentioned for potential side effects. Some patients became hypo- glycemic after treatment. We thus investigated our hyperkalemic patients and their response to treatment with insulin and glucose. Methods: This is a tertiary transfer hospital serving over 90,000 emergency visits annually. We treat hyperkalemic patients based on ACLS recommendations. A cross-sectional, cohort, observa- tion study was undertaken from May 2004 to April 2009. We collected data on hyperkalemic patients treated to review their demographics and co-morbidities that may predispose to hypogly- cemia. We used multivariable analysis to check potential risks that may predispose to hypoglycemia. Results: There were 160 pa- tients treated for hyperkalemia. Seven cases were excluded and 153 patients were enrolled. There were 76 men and 77 women, with ages ranging from 41 to 96 years (median: 74, interquartile range 6582). About their hyperkalemia: 56 (36.6%) were mild, 63 (41.2%) were moderate, and 34 (22.2%) were severe. Most had multiple systemic illnesses, and renal diseases were the leading co-morbidity: 21(13.7%) received replacemental dialysis, another 86 (56.2%) had documented chronic kidney diseases. Emergency department studies revealed elevated serum creatinine in 133 (86.9%) patients, including 4 (2.6%) with acute renal failure. Seven (4.6%) patients were hypoglycemic 49 –240 (median 79) min after insulin treatment, and 5/7 were symptomatic. No risk factor could be identified that predisposed to the hypoglycemia after insulin and glucose treatment. Conclusion: The risk of hy- poglycemia is real after standard ACLS treatment of hyperkalemia with insulin and glucose. Most instances happened 1–2 h after insulin treatment and were symptomatic. We should pay attention to potential hypoglycemia in hyperkalemic patients who receives insulin treatment, especially when their sensorium is impaired. e A RANDOMIZED, BLINDED, CONTROLLED CLIN- ICAL TRIAL OF 1000 CC VERSUS 500 CC ORAL CON- TRAST IN ADULTS UNDERGOING ABDOMINAL CT SCANS. L. Moreno-Walton, Department of Emergency Medi- cine, Louisiana State University Health Sciences Center, New Orleans, LA; F. Azubiuke, Mt. Sinai Medical Center, Miami, FL; M.S. Radeos, New York Hospital, Queens, NY; A. Baquero, M.T. Ryan, Lincoln Medical and Mental Health Center, Bronx, NY. Objective: To determine if reducing oral contrast volume to 500 cc results in more rapid oral contrast administration with- out increasing the percentage of technically inadequate com- puted tomography (CT) scans of the abdomen. Methods: Pro- spective randomized blinded study at an urban Level I trauma center. We enrolled subjects 18 years of age presenting to the emergency department (ED) who had an abdominal CT scan ordered. Subjects were excluded if they were pregnant or unstable. They were randomized into two groups using num- bered envelopes. We diluted 30 cc of oral contrast (diatrizoate meglumine and diatrizoate sodium) in 500 cc (study group) or 1000 cc water (control group). Data were collected by physi- cian questionnaire. Radiologists were blinded to study alloca- tion. Analysis was by chi-squared for categorical and Kruskal- Wallis for non-parametric data. Results: There were 139 patients randomized to each group; 160 (58%) were males. There was no statistical significance between the control and study groups in the median patient age (45 vs. 41 years, p 0.12), number of CT scans that answered the clinical question (94% vs. 91%, p 0.41), number read as acceptable by radiology (87% vs. 85%, p 0.55), number who required subsequent studies (14% vs. 16%, p 0.74), total time from beginning contrast to completing CT scan (146 vs. 140 min, p 0.70), number of patients who vomited (9.5% vs. 5.7%, p 0.26), and number who underwent surgery (8.7% vs. 10.4%, p 0.64). The time to consume the 500 cc was significantly less (20 min) than time to consume the 1000 cc (30 min), p 0.0001. Patients were more likely to complete the 500-cc volume than the 1000-cc volume (91.2% vs. 73.6%), p 0.001; odds ratio 1.41 (95% confidence interval 1.2–1.7) even after adjusting for gender and age. Conclusions: Patients consume the 500-cc solution faster and the resulting CT scans have similar technical acceptability compared with the 1000-cc solution. Future studies should focus on even smaller amounts of oral contrast volume for abdominal CT scans. e SENSITIVITY OF A NEW DIAGNOSTIC SCALE FOR PULMONARY THROMBOEMBOLISM IN TWO UNIVERSITY-AFFILIATED HOSPITALS. O. Palla ´s, M.T. Martı ´nez, Department of Emergency Medicine, Hospital del Mar, Barcelona, Catalunya, SPAIN; M. Marin ˜osa, M. Paye ´s, Hospital Parc Taulı ´, Sabadell, SPAIN; F. Del Ban ˜o, A. Super- via, E. Skaf, Department of Emergency Medicine, Hospital del Mar, Barcelona, Catalunya, SPAIN; M.L. Iglesias, Hospital Parc Taulı ´, Sabadell, SPAIN; J.L. Echarte, Department of Emergency Medicine, Hospital del Mar, Barcelona, Catalunya, SPAIN. Introduction: Validated scales for grading the clinical suspicion of pulmonary thromboembolism (PT) are used in the emergency department setting. The Wells (WS) and the Ginebra (GS) scales have been prospectively validated but have limitations in our environment. Objectives: To compare the sensitivity of a new scale of clinical prediction of PT (Catalan scale) with WS and GS in two hospitals. Methods: There were 194 patients diagnosed with PT between 2004 and 2006. Diagnosis was confirmed by computed chest angiotomography or high-probability ventilation- perfusion (V/P) lung scanning. Hospital discharge records and imaging studies were reviewed. The WS, GS, and the Catalan scale (CS), were applied. Data were analyzed with SPSS 13.0 234 The Journal of Emergency Medicine

Hypoglycemia, an Uncommon but Real Complication of Standard Hyperkalmia Treatment

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income (p � 0.012). Conclusion: We concluded that there is a lowlevel of knowledge among caregivers of children � 13 years oldin reference to child car seat safety laws and guidelines in PR.Future efforts should be directed towards improving populationknowledge about the correct use of child car safety seats.

e HYPOGLYCEMIA, AN UNCOMMON BUT REALCOMPLICATION OF STANDARD HYPERKALMIATREATMENT. Y.C. Huang, Department of Emergency Med-icine, Chiayi Christian Hospital, Chiayi City, TAIWAN.

Introduction: Hyperkalemia is life-threatening and requires im-mediate treatment. A combination of 25 g glucose and 10 unitsregular insulin given intravenously over 15–30 min is suggested aspart of the standard treatment for hyperkalemia in AdvancedCardiac Life Support (ACLS); however, no precaution has beenmentioned for potential side effects. Some patients became hypo-glycemic after treatment. We thus investigated our hyperkalemicpatients and their response to treatment with insulin and glucose.Methods: This is a tertiary transfer hospital serving over 90,000emergency visits annually. We treat hyperkalemic patients basedon ACLS recommendations. A cross-sectional, cohort, observa-tion study was undertaken from May 2004 to April 2009. Wecollected data on hyperkalemic patients treated to review theirdemographics and co-morbidities that may predispose to hypogly-cemia. We used multivariable analysis to check potential risks thatmay predispose to hypoglycemia. Results: There were 160 pa-tients treated for hyperkalemia. Seven cases were excluded and153 patients were enrolled. There were 76 men and 77 women,with ages ranging from 41 to 96 years (median: 74, interquartilerange 65�82). About their hyperkalemia: 56 (36.6%) were mild,63 (41.2%) were moderate, and 34 (22.2%) were severe. Most hadmultiple systemic illnesses, and renal diseases were the leadingco-morbidity: 21(13.7%) received replacemental dialysis, another86 (56.2%) had documented chronic kidney diseases. Emergencydepartment studies revealed elevated serum creatinine in 133(86.9%) patients, including 4 (2.6%) with acute renal failure.Seven (4.6%) patients were hypoglycemic 49–240 (median 79)min after insulin treatment, and 5/7 were symptomatic. No riskfactor could be identified that predisposed to the hypoglycemiaafter insulin and glucose treatment. Conclusion: The risk of hy-poglycemia is real after standard ACLS treatment of hyperkalemiawith insulin and glucose. Most instances happened 1–2 h afterinsulin treatment and were symptomatic. We should pay attentionto potential hypoglycemia in hyperkalemic patients who receivesinsulin treatment, especially when their sensorium is impaired.

e A RANDOMIZED, BLINDED, CONTROLLED CLIN-ICAL TRIAL OF 1000 CC VERSUS 500 CC ORAL CON-TRAST IN ADULTS UNDERGOING ABDOMINAL CTSCANS. L. Moreno-Walton, Department of Emergency Medi-cine, Louisiana State University Health Sciences Center, NewOrleans, LA; F. Azubiuke, Mt. Sinai Medical Center, Miami, FL;M.S. Radeos, New York Hospital, Queens, NY; A. Baquero, M.T.Ryan, Lincoln Medical and Mental Health Center, Bronx, NY.

Objective: To determine if reducing oral contrast volume to500 cc results in more rapid oral contrast administration with-

out increasing the percentage of technically inadequate com-puted tomography (CT) scans of the abdomen. Methods: Pro-spective randomized blinded study at an urban Level I traumacenter. We enrolled subjects � 18 years of age presenting to theemergency department (ED) who had an abdominal CT scanordered. Subjects were excluded if they were pregnant orunstable. They were randomized into two groups using num-bered envelopes. We diluted 30 cc of oral contrast (diatrizoatemeglumine and diatrizoate sodium) in 500 cc (study group) or1000 cc water (control group). Data were collected by physi-cian questionnaire. Radiologists were blinded to study alloca-tion. Analysis was by chi-squared for categorical and Kruskal-Wallis for non-parametric data. Results: There were 139patients randomized to each group; 160 (58%) were males.There was no statistical significance between the control andstudy groups in the median patient age (45 vs. 41 years, p �0.12), number of CT scans that answered the clinical question(94% vs. 91%, p � 0.41), number read as acceptable byradiology (87% vs. 85%, p � 0.55), number who requiredsubsequent studies (14% vs. 16%, p � 0.74), total time frombeginning contrast to completing CT scan (146 vs. 140 min,p � 0.70), number of patients who vomited (9.5% vs. 5.7%,p � 0.26), and number who underwent surgery (8.7% vs.10.4%, p � 0.64). The time to consume the 500 cc wassignificantly less (20 min) than time to consume the 1000 cc(30 min), p � 0.0001. Patients were more likely to complete the500-cc volume than the 1000-cc volume (91.2% vs. 73.6%),p � 0.001; odds ratio 1.41 (95% confidence interval 1.2–1.7)even after adjusting for gender and age. Conclusions: Patientsconsume the 500-cc solution faster and the resulting CT scanshave similar technical acceptability compared with the 1000-ccsolution. Future studies should focus on even smaller amountsof oral contrast volume for abdominal CT scans.

e SENSITIVITY OF A NEW DIAGNOSTIC SCALEFOR PULMONARY THROMBOEMBOLISM IN TWOUNIVERSITY-AFFILIATED HOSPITALS. O. Pallas, M.T.Martınez, Department of Emergency Medicine, Hospital delMar, Barcelona, Catalunya, SPAIN; M. Marinosa, M. Payes,Hospital Parc Taulı, Sabadell, SPAIN; F. Del Bano, A. Super-via, E. Skaf, Department of Emergency Medicine, Hospital delMar, Barcelona, Catalunya, SPAIN; M.L. Iglesias, HospitalParc Taulı, Sabadell, SPAIN; J.L. Echarte, Department ofEmergency Medicine, Hospital del Mar, Barcelona, Catalunya,SPAIN.

Introduction: Validated scales for grading the clinical suspicionof pulmonary thromboembolism (PT) are used in the emergencydepartment setting. The Wells (WS) and the Ginebra (GS) scaleshave been prospectively validated but have limitations in ourenvironment. Objectives: To compare the sensitivity of a newscale of clinical prediction of PT (Catalan scale) with WS and GSin two hospitals. Methods: There were 194 patients diagnosedwith PT between 2004 and 2006. Diagnosis was confirmed bycomputed chest angiotomography or high-probability ventilation-perfusion (V/P) lung scanning. Hospital discharge records andimaging studies were reviewed. The WS, GS, and the Catalanscale (CS), were applied. Data were analyzed with SPSS 13.0

234 The Journal of Emergency Medicine