I'IHlTlIBlR UNIVERSITY

OF SCIEITCE Fll'lD TECHNOLOGY

FACULTY OF HEALTH AND APPLIED SCIENCES

DEPARTMENT OF HEALTH SCIENCES

QUALIFICATION: BACHELOR OF HEALTH INFORMATION SYSTEM MANAGEMENT

QUALIFICATION CODE: 08BHIS LEVEL: 5

COURSE CODE: BPP5215 COURSE NAME: BASIC PATHOPHYSIOLOGY

SESSION: JANUARY 2018 PAPER: THEORY

DURATION: 3 HOURS MARKS: 100

SECOND OPPORTUNITY EXAMINATION QUESTION PAPER

EXAMINER MR. .IOMIN GEORGE

MODERATOR:MS. JANSEN CHARMAINE

INSTRUCTIONS

PWP!‘Answer ALL the questions.

Write clearly and neatly.

Number the answers clearly.Write all answers in the answer booklet provided.

1. NONE.

PERMISSIBLE MATERIALS

THIS QUESTION PAPER CONSISTS OF 6 PAGES (Including this front page)

QUESTION 1

SECTION A [40 MARKS]

[15 MARKS]

1. Evaluate the statements in each numbered section and select the most appropriate Answer or

phrase from the given possibilities. Write the appropriate letter next to the number ofthe

statement/phrase in the ANSWER BOOK.

1.1

1.2

1.3

1.4

1.5

Outpouching or localized dilation of a vessel wall or cardiac chamber is best

known as which of the following terms:

A. Thrombus

B. Aneurysm

C. Embolism

D. Edema

Which of the following conditions refers to decrease in both systolic and diastolic

BP on standing; accompanied by dizziness, blurred or loss of vision, or syncope:

A. Otrthostatic Postural Hypotension

B. Chronic Hypotension

C. Idiopathic Hypotension

D. Portal Hypertension

An objective indication of disease that is obvious to an observer is referred to as a:

A. SufferingB. Sign

C. SyndromeD. Symptom

Smoking causes:

A. Bronchodilatation

B. Bronchoconstriction

C. Swelling ofthe lungsD. Atrial fibrillation

The observation of tissues with the naked eye to study disease is called:

A. Molecular pathologyB. Experimental PathologyC. Gross PathologyD. Clinical Pathology

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1.6

1.7

1.8

1.9

1.10

1.11

1.12

Pyelonephritis relates to inflammation of the:

A. Parenchyma and the pelvis of the kidney

B. Pelvis and the urinary bladder

C. Parenchyma and the urinary bladder

D. Renal system

Rheumatoid arthritis is:

A. An inflammatory condition

B. An infectious disease

C. A condition that only affects women

D. A condition that only affects men

The death of tissue as a result of ischaemia is caused by:A. Apoptosis

B. Infarction

C. Vasculitis

D. Shock

Virchow's triad refers to:

A. Alpha, beta and gamma granules

B. Myocardial infarction, cerebral infarction and pulmonary embolism

C. Fibrin, Fibrinogen, and Fibronectin

D. Changes in intimal vessel surface, pattern of blood flow, and blood

constituents

Which ofthe following cell states is an example of irreversible cell injury:

A. Calcification

B. Aging

C. Necrosis

D. Injury

Peptic ulcer mainly occurs in the:

A. Large intestine

B. Mouth

C. Stomach

D. Spleen

Which of the following is not a clinical feature of inflammation:

A. Calor

B. Rubor

C. Tumor

D. Dalor

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1.13 The alternating bands of white platelets and red blood cells in thrombi are known as: [1]

A. Lines of Sam

B. Lines of Zorh

C. Lines of Zane

D. Lines of Zahn

1.14 Cystitis is inflammation of the: [1]

A. Gall bladder

B. Stomach

C. Liver

D. Urinary bladder

1.15 The development of a disease is known as : [1]

A. EtiologyB. MorphologyC. PathogenesisD. Pathology

QUESTION 2 [15 MARKS]

2. Assess the following statements and decide whether they are true or false. Write only the

number of the question and next to it true for a true statement and false for a false statement

next to the number of the question in the ANSWER BOOK.

2.1 In oliguria, urine output is more than 400ml/day. [1]

2.2 Cigarette smoking is a common etiology for Emphysema. [1]

2.3 Staphylococcus aureus is the common causative agent in Pneumonia. [1]

2.4 MI occur due to narrowing of one or more choroid plexus. [1]

2.5 Stress can increases the risk of acid production. [1]

2.6 Tuberculosis can be transmitted by drinking no pasteurized milk. [1]

2.7 Endocrine stimulation can inhibits hyperplasia. [1]

2.8 Enteric fever is caused by salmonella typhi. [1]

2.9 Peak bone mass can achieved between 35 and 45 years of age. [1]

2.10 lschemic stroke is also known as mini stroke. [1]

2.11 Inflammation of bone marrow is known as osteoporosis. [1]

2.12 Koch’s disease is also known as COPD. [1]

2.13 Incidence of Urinary tract infection is most common in men. [1]

2.14 Helicobacter pylori are the causative agent for peptic ulcer. [1]

2.15 Splenomegaly is a common complication in cirrhosis of Liver. [1]

QUESTION 3 [10 MARKS]

3. You are required to select the description in column B that best matches the term in column A.

Write only the letter of column A and next to it the matching number in column B in your

answer booklet (Each correct answer earn 1 mark)

Column A Column B

3.1 Hemorrhage A. Pleural effusion

3.2 Pancreatitis B. Atherosclerosis

3.3 Centriloble C. Arthritis

3.4 Gallbladder D. Cholelithiasis

3.5 Jaundice E. Emphysema

3.6 Hypovolemia F. Shock

3.7 Hyperlipidaemia G. Stroke

3.8. Anti-citrullinated protein antibodies H. Bilirubin

3.9 Pleurisy |. Gallstones

3.10. Breath test J. Peptic ulcer

SECTION B [20 MARKS]

QUESTION 4

4.1 Enumerate various stages in the fate of the Thrombus.

4.2 Define and describe the various types of necrosis.

4.3 Write short note on TB’s diagnosis and symptoms.

4.4 Briefly discuss the Gouty Arthritis.

SECTION 9140 MARK51

QUESTION 5

5.1 Draw and label the parts of a cell cycle.

Elaborate the stages of Mitosis in eukaryotic cells.

5.2 Describe Rheumatoid arthritis including the following

Types.

Risk factors.

Complication.

Diagnosis.

Clinical manifestation.W909”?

GOOD LUCK!!!!

[20 MARKS]

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[40 MARKS]

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